Page 1 of 7 MATERIAL SAFETY DATA SHEET Section 1 Company and Product Identication Product Name Part Number Product Use Series Name Manufacturer CONTRAD 70 81911 For In Vitro Diagnostic Use. See product literature for details. ACCESS® Beckman Coulter, Inc. 4300 Harbor Blvd. Fullerton, CA 92835-3100, U.S.A. Beckman Coulter Ireland Inc. Mervue Business Park Mervue, Galway, Ireland 353 91 774068 Refer to attached list, Document ID: 472050, for local distributor and emergency phone numbers. Doc. ID: 81911-75 AD . Revised (year/month/day) 2008/03/24 EC REP Address Distributor and Emergency Phone No. Section 2 Hazards Identication Emergency Overview White; Translucent; Liquid; Mild odor Nonammable aqueous solution. Corrosive; eye, skin burns, severe respiratory tract irritant. Physical Hazards Potential Health Effects Summary Potential Environmental Effects Product Hazard Classications No physical hazards were determined from a review of available literature. Exposure may cause irritation or burns to respiratory tract, skin, and eyes. Corrosive effects may be delayed. See Section 11 Toxicological Information for more detailed health information. Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Meets Hazardous Criteria for Preparation/Mixture EU: C;R34 WHMIS: Exempt US OSHA: Hazardous . ©2008 Beckman Coulter, Inc. Global MSDS – English CONTRAD 70 Page 2 of 7 Doc. ID: 81911-75 AD Section 3 Composition and Information on Ingredients Hazardous Ingredients: Chemical Name Potassium Hydroxide Hazard Classication of Pure Ingredients CAS # 1310-58-3 EINECS # 2151813 % by wt. < 5% EU C;R22-35 WHMIS D1B; E US OSHA Corrosive Toxic Water-Reactive See Section 15 Regulatory Information for additional information on hazard classications. See Section 16 for Risk Phrases and WHMIS Classication Description. Section 4 First Aid Measures Inhalation Eye Contact If product is inhaled, move exposed individual to fresh air. If individual is not breathing, begin articial respiration immediately and obtain medical attention. If product enters eyes, wash eyes gently under running water for 15 minutes or longer, making sure that the eyelids are held open. If pain or irritation occur, obtain medical attention. In case of skin contact, ush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. If pain or irritation occur, obtain medical attention. If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical attention. Skin Contact Ingestion Section 5 Fire Fighting Measures Flammable Properties Extinguishing Media Special Fire and Explosion Hazards Hazardous Combustion Products Protective Equipment for Fireghters Nonammable aqueous solution. Use extinguishing media suitable for surrounding re. None identied. Due to the composition and volume of this product, combustion products generated from it are not expected to present a signicant hazard. Self-contained breathing apparatus is recommended for reghters in all chemical re situations. Section 6 Accidental Release Measures Personal Precautions Spill and Leak Procedures Environmental Precautions Avoid skin contact. Use good laboratory procedures. Absorb spilled material with an appropriate inert, non-ammable absorbent and dispose according to local regulations. Contain spill to prevent migration. CONTRAD 70 Page 3 of 7 Doc. ID: 81911-75 AD Section 7 Handling and Storage Handling Precautions Recommended Storage Conditions Avoid inhaling, ingesting, and contact with eyes and skin. Keep away from incompatible material (see Section 10). To maintain efcacy, store according to the instructions in the product labeling. Section 8 Exposure Controls and Personal Protection Exposure Limits US OSHA: ACGIH: Potassium Hydroxide None established 2 mg/m3 Ceiling None established None established None established No special engineering controls are required. Use with good general ventilation. Under normal conditions, the use of this product should not require respiratory protection. If overexposure should occur and ventilation is not adequate to maintain airborne concentrations at acceptable levels, the use of respiratory protection should be evaluated by a qualied professional. Safety glasses or chemical goggles should be worn to prevent eye contact. Impervious gloves, such as Nitrile or equivalent, should be worn to prevent skin contact. DFG MAK: NIOSH Japan Engineering Controls Respiratory Protection Eye Protection Skin Protection Section 9 Physical and Chemical Properties Physical State Color Transparency Odor Odor Threshold pH Freezing Point Boiling Point Flash Point Evaporation Rate Flammability (Solid, Gas) Flammable Limits Liquid White Translucent Mild odor Not applicable 13 Not available >212°C (413.6°F) Not applicable Not available Not applicable Not applicable CONTRAD 70 Page 4 of 7 Doc. ID: 81911-75 AD Section 9 Physical and Chemical Properties (Continued) Vapor Pressure Vapor Density Specic Gravity Solubility Water Organic Coefcient of Water/Oil Distribution Autoignition Temp. Decomposition Temperature Percent Volatiles Miscible Not available Not available Not applicable Not available Not applicable Not available Not available 1.06 @20°C Section 10 Stability and Reactivity Stability Hazardous Incompatibilities Stable under normal temperatures and pressures. Strong acids Strong bases Strong oxidizers When stored as labeled, no known hazardous decomposition products are formed during the shelf-life of this product. Keep away from incompatible material. Hazardous Decomposition Products Conditions to Avoid Section 11 Toxicological Information Toxicity Data for Hazardous Ingredients Potassium Hydroxide Oral LD50 Rat: 214 mg/kg The most likely routes of exposure are skin, eye contact and inhalation. Inhalation of dilute alkaline mists may result in irritation of mucous membranes with sore throat, coughing, difculty in breathing; intense exposure, the lungs may ll with uid. Contact with dilute solutions may cause irritation or skin injury with redness, ssures and white patches. Eye contact may result in severe burns with possible loss of sight, irritation of eyes and eyelids, pain and intense watering. Ingestion may result in burns to the mouth, throat and stomach with burning sensations in the mouth, abdominal pain, vomiting, diarrhea, shock and loss of consciousness. Although its concentration in the product is low, potassium hydroxide is toxic by ingestion. Primary Routes of Exposure Potential Effects of Acute Exposure CONTRAD 70 Page 5 of 7 Doc. ID: 81911-75 AD Section 11 Toxicological Information (Continued) Potential Effects of Chronic Exposure Repeated skin contact with dilute alkaline may cause irritation with redness and swelling or burns. Repeated eye contact may cause conjunctivitis with redness, swelling and watering or burns. Depending upon concentration, repeated ingestion may result in inammatory or ulcerative effects on the mouth with redness, swelling and sores in the mouth. Symptoms may include: coughing, headache, fatigue, nausea, vomiting, dizziness, blurred vision, red and watery eyes, abdominal pain and unconsciousness. No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA or 67/548/EEC Annex I. None identied. Individuals with eye and skin disorders may nd these conditions aggravated by exposure to this product. Symptoms of Overexposure Carcinogenicity Other Effects Conditions Aggravated by Exposure Section 12 Ecological Information Ecotoxicity Potassium Hydroxide 24 Hr LC50 Gambusia afnis: 80.0 mg/L No information available. No information available. No information available. No information available. Biodegradability Bioaccumulation Mobility Other Adverse Effects Section 13 Disposal Considerations Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance with federal, state and local regulations. If unsure of the applicable requirements, contact the authorities for information. Section 14 Transport Information Shipping Information Shipping Name UN/ID Number Packing Group Potassium Hydroxide Solution 1814 II 8 Corrosives None Not applicable 8L 8 Corrosive substances None IATA Hazard Class Subsidiary Risk Special Provisions IATA ERG Code IMDG Hazard Class Subsidiary Risk CONTRAD 70 Page 6 of 7 Doc. ID: 81911-75 AD Section 14 Transport Information (Continued) Special Provisions Marine Pollutant None No ORM-D Consumer Commodity None DOT Exception 153.154(c) (US ground only) 154 8 Corrosive substances C5 None 1814 8 Corrosives None None 154 US DOT Hazard Class Subsidiary Risk Special Provisions NAERG Number European ADR ADR Classication Classication Code/ Subsidiary Risk Canadian TDG PIN TDG Classication Subsidiary Risk Special Provisions NAERG Number Section 15 Regulatory Information US Federal and State Regulations SARA 313 CERCLA RG’s, 40 CFR 302.4 California Proposition 65 Massachusetts MSL New Jersey Dept. of Health RTK List Pennsylvania RTK EU Labeling Classication Classication Corrosive No ingredients listed. Potassium Hydroxide is listed. No ingredients listed. Potassium Hydroxide is listed. Potassium Hydroxide is listed. Potassium Hydroxide is listed. Risk and Safety Phrases R34 Causes burns. S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). Canada This product is exempt from WHMIS label and MSDS requirements. PIN: 1814 CONTRAD 70 Page 7 of 7 Doc. ID: 81911-75 AD Section 15 Regulatory Information (Continued) Ingredients on Ingredient Disclosure List: Ingredients with unknown toxicological properties: Potassium Hydroxide Product is exempt Some hazardous ingredients listed in Section 15 are below OSHAs and WHMIS’ 1.0% w/w (0.1% for carcinogens) or EU’s ingredient specic concentrations required for reporting in Section 3. Section 16 Other Information Beckman Coulter Safety Rating Flammability (Section V): 0 Health (Section XI): 3 Reactivity with Water (Section X): 0 Contact (Section VIII): 3 Code 0=none 1=slight 2=caution 3=severe Revision Changes Risk Phrases and WHMIS Classication Description From Section 3 Reformatted Sections 2, 3, 5, 8, 9, 12, 15, and 16 per ANSI Z400.1-2004 Standard. R22 Harmful if swallowed. R35 Causes severe burns. D1B - Acute Dermal Toxicity D1B - Acute Inhalation Toxicity D1B - Acute Oral Toxicity E - Corrosive Material For further information, please contact your local Beckman Coulter representative. WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS. Printed in U.S.A.
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