CELL CYCLE AND CANCER - Cell Division Mitosis • During mitosis, the cell’s nucleus divides into two new nuclei. One copy of the DNA is distributed into each of the two daughter cells. Cell Division The -Cell Cycle - Cell Division Length of the Cell Cycle How long does it take for a cell to go through one cell cycle? It all depends on the cell. A human liver cell, for example, completes one cell cycle in about 22 hours, as shown in the graph. Study the graph and then answer the following questions. - Cell Division Length of the Cell Cycle • Reading Graphs: – What do the three curved arrows outside the circle represent? –The longest curved arrow represents the cell’s interphase; the shortest represents cytokinesis; and the middle one represents mitosis. - Cell Division Length of the Cell Cycle • Reading Graphs: • In what stage of the cell cycle is the wedge representing growth? – Interphase Length of the Cell Cycle • Interpreting Data: – In human liver cells, how long does it take DNA replication to occur? –10 hours - Cell Division Length of the Cell Cycle • Drawing Conclusions: – In human liver cells, what stage in the cell cycle takes the longest time? – Interphase - Cell Division Structure of DNA • The DNA molecule is shaped like a twisted ladder. • How do the Nitrogen bases pair up? • Adenine – Thymine • Cytosine - Guanine - Cell Division • What is it? Replication of DNA • When DNA make exact copy of itself • Do the nitrogen bases have to match up? • YES!! • How? • Adenine – Thymine • Cytosine - Guanine Sequencing Can you name the stages and phases of Cell Cycle? Interphase Cell grows, makes a Mitosis: copy of DNA. Cytokinesis Prophase Chromosomes and Cell pinches in two; each spindle fibers form; daughter cell has same number nuclear envelope breaks of identical chromosomes. down. The Cell Cycle Chromosomes stretch out; Chromosomes line up new nuclear envelope forms Mitosis: across the center and around chromosomes. attach to a spindle fiber. Anaphase Mitosis: Centromeres split; Mitosis: Telophase chromatids separate and Metaphase move to opposite ends. What Is Cancer? • Let’s find out • You will work in groups of 3 • Each group member will learn and then teach specific information about Cancer to the other team mates! • 1st member will teach: WHAT IS CANCER • 2nd member: TREATING CANCER • 3rd member: CANCER PREVENTION • Each member will take notes • Finally everyone will have to answer 3 specific questions – we will review them!! - Cancer What Is Cancer?