Marine and botanical lipids as immunomodulatory and therapeutic agents in the treatment of rheumatoid arthritis. DeLuca P, Rothman D, Zurier RB. Rheum Dis Clin North Am. 1995 Aug;21(3):759-77. University of Massachusetts Medical Center, Division of Rheumatology, Worcester 10655, USA. Fish and plant seed fatty acids have antiinflammatory and immunomodulating properties that make them of potential use in the treatment of rheumatoid arthritis. A better understanding of their effects on the immune system ultimately may lead to the development of more benign therapy for rheumatoid arthritis patients.