Lesson Plan with Technology Integration (DOC download) by nikeborome

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									                                    Lesson Plan for Henrico 21 Awards

Teacher Name:         Robert Sean Pratt
Lesson Title: Human Genome and Genetic disorders
Target Grade/Subject: 10th grade/ Biology I
Length:       90 minutes

Technology Use
Tools and Resources Students will need access to their laptops and the internet. They will use a photo
editing software (Picasa) and a web browser (Internet Explorer/ Firefox with Shockwave) to complete an
online presentation module.

Evaluation Procedure
Essential questions or objectives: Students will identify on which chromosomes common genetic
disorders lie and research one genetic disorder of their choosing. A worksheet will be provided for a portion
of the assignment and a rubric will be used for the research project.

Assessment of objectives: First, students will identify on which human chromosomes several disorders
have been found. They will locate different common disorders on the human chromosomes. (See Gene
Gateway: Exploring Genes and Genetic Disorders) Secondly, they will compile research information related
to one disorder. Rather than write a traditional research paper, students will create an informational Capzle
about an assigned genetic disorder. A Capzle is a storyline made up of individual moments that would
contain information, images to present your material. The audience for this presentation is either someone
who has just been diagnosed as having this genetic disorder or someone who is the parent or child of
someone who has been diagnosed. The Capzle will include a collage of images relevant to the disorder
and answer several key questions about the disorder (See Genetic Disorder Capzle).

Lesson Development
Process/Tasks : Students will go to the class website (mrpratt.com) and navigate to the DNA section.
From there they will choose the human genome project link. Once students have accessed the web site,
they will go through each human chromosome looking for traits or disorders that they are familiar with. The
end of the assignment sheet will give them suggestions as to what traits may be considered and as to how
many times they may be used. Students will also identify how many nucleotide bases are present on each
human chromosome. The second portion of this lesson includes a research project where students will
research one genetic disorder provided by the teacher. They will collect several images that are relevant to
the disorder and create a collage. This collage will be uploaded to an online presentation tool (www.
capzles.com). Students will also have to answer several questions related to their disorder; description of
the disorder, signs and symptoms and treatment and prognosis questions. Students will log into an account
created by the teacher to post their information. Directions for gathering and posting the information will be
given to the students. At the deadline for the project, students will be given the opportunity to present their
research and field questions from the teacher.
                            www.mrpratt.com – anatomy - genetics – human genome project




       Identify five common traits or diseases found on human chromosomes. You may use the list of
       common traits or diseases at the end of this assignment and match them with the correct
       chromosome. Also indicate how many bases are found on each chromosome.
Chromosome    # of bases                                         Traits or diseases
  number


   1
   2
   3
   4
   5
   6
   7
   8
   9
  10
  11
  12
  13
  14
  15
  16
  17
  18
  19
  20
  21
  22
  X
   Y
                                      # of                                               # of
                 Trait                                           Trait
                                     times                                              times

              Albinism                4         Glucose/ galactose malabsorption         1
    Alcoholism, susceptibility to     1                        Goiter                    3
         Alzheimer disease            5            Growth hormone deficiency             1
              Autism                  1                  Hair color, brown               2
          Bladder cancer              3                   Hair color, red                1
           Brain cancer               1                    Hemangioma                    1
           Breast cancer              8                     Hemophilia                   1
     Carpal tunnel syndrome           1                   HIV expression                 1
        Cat eye syndrome              1          HIV susceptibility, resistance to       1
              Cataract                8                      Insomnia                    1
    Cholesterol lowering factor       1                   Leprechaunism                  1
         Chronic infections           1                      Leukemia                   15
           Colon cancer               4                   Limb deformity                 1
    Colorblindness, blue cones        1                    Liver cancer                  1
Colorblindness, blue monochromatic    1                    Lung cancer                   5
 Colorblindness, red cone pigment     1              Malaria, susceptibility to          1
         Colorectal cancer            6               Malignant brain tumors             1
Colorblindness, green cone pigment    1             Maple syrup urine disease            2
       Cri-du-chat syndrome           1              Measles, susceptibility to          1
             Deafness                17                 Mental retardation               1
         Dental anomalies                                    Migraine                    2
         Diabetes insipidus           1                 Muscular dystrophy               5
         Diabetes mellitus           10                 Nicotine addiction               1
     Down syndrome adhesion           1                       Obesity                    7
             Dwarfism                 1                Obesity and red hair              1
              Dyslexia                3                     Oral cancer                  1
            Emphysema                 1           Osteoarthritis, susceptibility to      4
        Enuresis, nocturnal           2                   Ovarian cancer                 7
              Epilepsy                9                  Pancreatic cancer               3
        Esophageal cancer             1                   Prostate cancer                5
         Eye color, brown             1                   Schizophrenia                  5
      Eye color, green/ blue          1                       Scurvy                     1
         Fish-eye disease             1             Sex determining region Y             1
        Fish-odor syndrome            1                    Short stature                 2
   Fragile X mental retardation       1                 Sickle cell anemia               1
           Gastric cancer             1                   Taste receptors                2
             Gigantism                1      UV induced skin damage, vulnerability to    1
 Genetic Disorder Capzle
 Rather than write a traditional research paper, you
 will create an informational Capzle about your assigned genetic disorder.
 Capzles are storylines made up of individual moments that would contain
 information, images, videos, or music, to present your material. Your
 audience for this brochure is either someone who has just been diagnosed
 as having this genetic disorder or someone who is the parent or child of
 someone who has been diagnosed.
 Below is a basic outline as to what your Capzle should include. Remember
 that you are creating this presentation to be read by individuals who know
 NOTHING about this disorder and just found out they have it or someone
 they love has it. Try not to be too wordy or lengthy.
Procedure:
   1. Collect between 5 and 10 images related to your Genetic disorder. Create a collage
      of these images using the appropriate software found on your laptop. (40 pts)
   2. Research the following questions and write a summary of your answers. Your
      summary paragraph should be between 200 and 300 words. It should not exceed
      300 words.

           a. Description of the disorder (20 pts)
                   i. How it is inherited?
                  ii. Is it dominant or recessive? Sex-linked?
                 iii. What chromosome number is affected if any?
                 iv. How many births are affected? – or - What is the rate of occurrence?
           b. Signs & Symptoms (20 pts)
                   i. How is the individual affected? What happens to their body because of
                      the disorder?
                  ii. What are the signs & symptoms? How will you know you have it?
                 iii. List the parts of the body that are affected.
                 iv. How does the disorder progress? Over time, what happens to the
                      person who has the disorder?
           c. Treatment & Prognosis (20 pts)
                   i. Is there a test to see if someone has this disorder?
                  ii. What treatments are available?
                 iii. How long can a person be expected to live with this disorder?
                 iv. Provide the name, phone number and street address of at least TWO
                      organizations that parents can access for support and more
                      information on the disorder

   3.    Once you have gathered your information, log on to www.capzles.com and find the
        capzle for your class.
           a. login: dsf_biology
           b. password: freeman
           c. Once you found your class' capzle, click the button "edit capzle" in the upper
               right hand corner.
           d. The “add content” button allows you to add a "moment". Choose “upload
               directly to my timeline” and upload your collage.
           e. Once your collage has been uploaded, type your disorder and your name in
               the title window and type your research in the description window.
           f. Upon completion of your entry, click the (X) and then "I'm finished" button
               found in the upper right hand corner.
  Present the presentation to the class. (+20 pts)

 Genetic Disorders:
 You may choose a genetic disorder that is not on this list with permission.
 To begin, you will find information at the following web site:

 http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gnd&part=A272



Achondroplasia                                      Thalassemia
Amyotrophic lateral sclerosis                       Testicular feminization
Apert Syndrome                                      syndrome
Alzheimer's disease                                 Thrombocytopenia
Autism                                              Tourette's syndrome
Bipolar disorder                                    von Hippel-Lindau disease
Cerebral Palsy                                      Wilson's disease
Cystic fibrosis                                     Xeroderma pigmentos
Cleft lip and palate
Crohn's disease
Down syndrome
Epilepsy
Fragile X syndrome
Hemochromatosis
Hemophilia
Huntington's disease
Marfan's syndrome
Muscular dystrophy
Neurofibromatosis
Niemann-Pick
Osteogenesis imperfecta
Parkinson's disease
Phenylketonuria
Porphyria
Progeria
Sickle cell anemia
Schizophrenia
Tay-Sachs disease

								
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