International Conference on Biomedical Engineering and Informatics

							                          3rd Annual Review
                          Agenda

11:30-12:00   Lunch
12:00-12:10   Welcome and Intros
12:10-12:45   Annual Progress Report (Guerlain)
12:45-1:30    Student Presentations (Lesniak, Baumgart)
1:30 - 2:15   Posters (outside health sciences library)
2:15 - 2:45   Diabetes Research Center (Patek)
2:45-3:05     Students and advisory board discussion
              (without exec committee)
3:05-3:25     Advisory Board finalizes recommendations
3:25-3:45     Group discussion (All)
3:45          Adjourn
   The National Library of Medicine supports 18 training centers to train
    scientific investigators and leaders in biomedical computing.
   The areas of training must be in health related domains:
         Health Care Delivery                   Focus of our grant:
         Basic Biomedical Research              “clinical informatics”
         Clinical & Health Services Research    (with some research
         Public Health                          here as well)
         Professional Education

                                                                          2
     Current NLM-funded Biomedical Informatics
                Training Programs
1. University of Colorado Denver/HSC Aurora (Denver, CO) [new in 2007]
2. University of Virginia Charlottesville (Charlottesville, VA) [new in 2007]
3. University of California Irvine (Irvine, CA)
                                                                Strong barrier
4. University of California Los Angeles (Los Angeles, CA)
                                                                to entry.
5. Stanford University (Stanford, CA)
6. Yale University (New Haven, CT)
7. Regenstrief/Indiana University (Indianapolis, IN)            But, once
8. Harvard University (Medical School) (Boston, MA)             funded, quite
9. Johns Hopkins University (Baltimore, MD)                     likely to be
10. University of Missouri-Columbia (Columbia, MO)              renewed over
11. Columbia University Health Sciences (New York, NY)          and over
12. Oregon Health & Science University (Portland, OR)           again.
13. University of Pittsburgh at Pittsburgh (Pittsburgh, PA)      We need to
14. Vanderbilt University (Nashville, TN)                       be in this
15. Rice University (Houston, TX)                               group on the
16. University of Utah (Salt Lake City, UT)                     next go-
17. University of Washington (Seattle, WA)                      around!
18. University of Wisconsin Madison (Madison, WI)
                                                                            3
        UVA T-15 Training Grant:
“A Systems Approach to Medical Informatics”

                        Our program directly addresses the IOM/NAE
                        recommendation for building a better healthcare
                        system by creating a multidisciplinary environment
                        in which systems engineers and healthcare
                        researchers collaboratively mentor trainees in
                        medical informatics.

                ~$3M 5-year renewable grant to fund:
               Short-term minority trainees (~ 4 annually)
                     Ph.D. students* (~ 7 annually)
                      and Postdocs* (~2 annually)
                         in Medical Informatics

    *Full-time trainees earn a degree in Systems & Information Engineering with
         research and mentorship focused on healthcare information topics.
              All trainees must be U.S. citizens or permanent residents.          4
Program broadened in 2009 to include all research
and training at the intersection of systems
engineering and medicine




          (Includes trainees & funding beyond NLM)
                                                     5
           Mission Statement
To train top-notch researchers who:
  1. are able to apply the techniques of systems and
     information engineering and medical informatics to
     address major open problems in medicine and
     healthcare delivery, and
  2. who are qualified for academic, governmental, and
     industry positions in which their technical skills and
     understanding of the biomedical domain will
     advance societal goals.



                                                              6
                       Sub-Goals
1. To recruit and retain high-quality research students
2. To increase collaborative work between engineers and
   clinicians/medical researchers at UVa in areas of biomedical informatics.
3. To disseminate research in three types of venues: a) clinical and
   biomedical, b) engineering, c) traditional medical informatics.
4. To develop and maintain a curriculum that supports careers in
   biomedical and clinical informatics from a Systems Engineering
   perspective
5. To mentor students in the art of conducting academic research
6. To provide trainees with external experiences to meet outside
   researchers and industry contacts and to enable them to make an
   impression on their research community.
7. To transfer technologies, processes, and research artifacts to the
   market, to medical practices, and/or to other researchers
8. To place trainees in academic and research positions around the
   country                                                            7
Introductions!




                 8
•   Name
•   Department
•   Research Interests
•   An interesting fact that (almost) no one in
    the room would know about you, that you’re
    willing to share




                                              9
                           Advisory Board
• Chair
   – Don E. Detmer, M.D., M.A. Professor of Public Health Sciences at UVA,
     Immediate Past President and CEO of the American Medical Informatics
     Association
• Internal
   – Barry Horowitz, Ph.D. Professor and Chair of the UVA SIE Department
   – Bill Knaus, M.D., Professor and Chair of Public Health Sciences
   – Sarah Farrell, Ph.D., APRN, Associate Professor of Nursing and Public
     Health Sciences, Associate Dean for Academic Programs, School of
     Nursing
   – Marshall Ruffin, M.D., M.P.H., M.B.A. Chief Technology and Health
     Information Officer, UVA Health System
• External
   – Richard I. Cook, M.D., Associate Professor of Anesthesiology and
     Director of the Cognitive Technologies Laboratory at the University of
     Chicago.
   – Jack W. Smith, M.D., Ph.D., Professor and Dean, University of Texas
     School of Health Information Sciences
   – Paul Tang, M.D., Chief Medical Information Officer, Palo Alto Medical
     Foundation, Consulting Associate Professor of Medicine (Biomedical
     Informatics), Stanford University

                                                                              10
                Executive Committee
• Chair and Co-Chair
   – Stephanie Guerlain, Ph.D., Associate Professor, Systems and
     Information Engineering
   – Jim Harrison, M.D., Ph.D. Associate Professor of Public Health
     Sciences and Pathology, Director of the Division of Clinical
     Informatics
• Faculty in the Dept of Systems & Information Engineering
   – Ellen Bass, Ph.D., Associate Professor
   – Greg Gerling, Ph.D. Assistant Professor
   – Stephen Patek, Ph.D. Associate Professor
• Faculty in the Dept of Public Health Sciences
   – Wendy Cohn, Ph.D., Associate Professor
   – Jason Lyman, M.D., M.S., Assistant Professor
• Director and Associate Dean, Health Sciences Library
   – Gretchen Arnold, MLS, AHIP



                                                                      11
                Health Care Mentors
•   Peggy Plews-Ogan, M.D. (Internal Medicine)
•   John Voss, M.D. (Internal Medicine)
•   Tracey Krupski, MD, MPH, (Urology)
•   Randy Jones, Ph.D, RN, (Nursing)
•   Reba Childress, MSN, FNP-BC (Nursing)
•   Keith Littlewood, M.D. (Anesthesiology)
•   Mark Kirk, M.D. (Emergency Medicine)
•   Ellen Lumpkin, Ph.D. (Neuroscience)
•   Tracey Hoke MD MSc (Pediatrics)
•   Steve Borowitz MD (Pediatrics)
•   Martha Hellems, M.D., M.S. (Pediatrics)
•   Beth Turrentine, R.N. (Surgery)
•   Jason Lyman, M.D., M.S. (Public Health Sciences)
•   Boris Kovatchev, Ph.D. (Psychiatry & Neurobehavioral Sciences)
•   Marcus Martin, M.D. (Chief Officer for Diversity and Equity, UVa)
                                                                   12
         Postdoctoal Trainees
      Current                    Past

• Sharon Meth, M.D.        • Kwangsik Nho, Ph.D,
• R. Lacey Colligan, M.D.,
  M.Sc.
• Andy Ortiz, M.D.

   Anticipated Openings

• 2 slots, must be hired
  between 7/1/10 - 6/1/11


                                                   13
              Predoctoral Trainees
         Current                   Past
•   Leigh Baumgart, M.S.    •   Barbara Mooney, M.A.
•   Justin DeVoge, M.S.     •   Matthew Wagner, M.S.
•   Collen Hughes, M.S.     •   Dave Bauer, M.S.
•   Akilah Hugine, M.S.     •   Matthew Bolton, Ph.D.
•   Daine Lesniak, M.S.
•   Aaron Williams, M.S.
•   Mark Farrington, M.S.
•   Lu Wang, M.S.*
•   Tipan Verella, M.S.*
    Anticipated Openings
• 2 slots, must be hired between
  7/1/10 - 6/1/11
                                   *Not NLM-funded
                                                        14
                M.S. Trainees*
      Current

•   Kim Brantley
•   Bill Carson
•   Elmer Kim
•   Angie Lee
•   Isabelle Rivest




                         *Not NLM-funded
                                           15
         Short-term Trainees
      Current                    Past
• Petheree Norman           •   Mangwi Atia
                            •   Michael Cary
                            •   Alexandra Coso
                            •   Sherry Springs
                            •   Tipan Verella
                            •   Terlene Romney
 Anticipated Openings       •   Douglas Lewis
• 3 slots, must be hired    •   Ted Perez
  between 7/1/10 - 6/1/11   •   Tashima Lambert



                                                  16
          Year 3 Progress
• Recruited new students
  - Aaron Williams, MS, Mark Farrington, MS, Tashima
    Lambert, Petheree Williams and Douglas Lewis, BA
• Recruited new mentors
  – Tracey Krupski, MD, MPH, Randy Jones, PhD, RN, Keith
    Littlewood, MD, Mark Kirk, MD, Martha Hellems, MD, MS,
    Beth Turrentine PhD, RN
• Other potential mentors
  - Peter Beling, PhD, Bill Knaus, MD, Gerry Learmonth PhD
• First trainee graduated
  - Matthew Bolton, Ph.D.
     • Hired as a research Scientist, NASA Ames/San Jose
       State University                                17
Trainees’ published/accepted manuscripts
1. Bauer D.T. & Guerlain S. (Accepted, 2010). Designing pharmacy-generated intravenous
   medication labels to support the medication use process. International Journal of Industrial
   Ergonomics.
2. Bauer, D.T., Guerlain, S., & Brown, P.J. (In Press). The design and evaluation of a graphical
   laboratory data display. Journal of the American Medical Informatics Association.
3. Baumgart, L.A., Gerling, G.J. & Bass, E.J. (2010). Characterizing the range of simulated
   prostate abnormalities palpable by digital rectal examination. Cancer Epidemiology, 34(1), 79-84.
4. Bolton, M. L., & Bass, E. J. (In Press). Formally verifying human-automation interaction
   as part of a system model: Limitations and tradeoffs. Innovations in Systems and
   Software Engineering: A NASA Journal.
5. Colligan, L., Anderson, J., Potts, H., Berman, J. (2010). Does the process map influence the
   outcome of quality improvement work? A comparison of a sequential flow diagram and a
   hierarchical task analysis diagram. BMC Health Services Research 10:7
6. Dunn Lopez, K., Gerling, G. J., Cary, M. P., Kanak, M. F. (In Press). Cognitive work analysis to
   evaluate the problem of patient falls in an inpatient setting. Journal of the American Medical
   Informatics Association
7. Guerlain, S., Hugine, A. & Wang, L. (2010). A comparison of four epinephrine auto-injector
   delivery systems: Usability and patient preference. Annals of Allergy, Asthma & Immunology
   104,172–177
8. Hughes, C., Patek, S.D., Breton, M. and Kovatchev, B.P. (In Press). Anticipating the next meal
   using meal behavioral profiles: a hybrid model-based stochastic predictive control algorithm for
   T1DM. Computer Methods and Programs in Biomedicine
9. Wellnitz, S.A., Lesniak, D.L., Gerling, G.J., and Lumpkin, E.A. (Accepted) The regularity of
   sustained firing reveals two populations of slowly adapting touch receptors in mouse hairy skin
   Journal of Neurophysiology                                                                     18
                   Posters/Presentations
1. Bass, E, Perez, T, Meth, S, Plews-Ogan, M, Helms, A, Bartelt, L. (2010). Assessing
   the quality of resident sign-out using post-call surveys. Poster presentation at the
   33rd Annual Meeting of the Society of General Internal Medicine, April 28-May 1,
   2010.
2. Baumgart, LA, Gerling, GJ, and Bass, EJ, (2010). Psychophysical detection of
   inclusions with the bare finger amidst softness differentials, Proceedings of the
   2010 IEEE Haptic Interfaces for Virtual Environment and Teleoperator Systems,
   Boston, MA, 17-20.
3. Bolton, M. L., & Bass, E. J. (2009). A method for the formal verification of human
   interactive systems. Proceedings of the 53rd Annual Meeting of the Human Factors and
   Ergonomics Society 764–768.
4. Bolton, M. L., & Bass, E. J. (2009). Enhanced operator function model: A generic human
   task behavior modeling language. Proceedings of the IEEE International Conference on
   Systems Man and Cybernetics, 2983–2990.
5. DeVoge, J.M., Bass, E. J., Atia, M, Bond, M., Waggoner-Fountain, L., & Borowitz, S.M.
   (2009). The development of a web-based resident sign-out training program. IEEE
   International Conference on Systems, Man, and Cybernetics
6. Hughes C. (2009). Information from insulin pumps improves continuous glucose
   monitoring-based detection and prevention of hypoglycemia. Poster Presentation at the
   Ninth Annual Diabetes Technology Meeting
7. S. D. Patek, Hughes C. Breton, M. & Kovatchev, B. P. (2009). Anticipating meals with
   behavioral profiles: towards stochastic model predictive control of T1DM. Seventh IFAC
   Symposium on Biological and Medical Systems.
8. Lesniak, D.R., Wellnitz, S.A., Gerling, G.J., Lumpkin, E.A. (2009). Statistical analysis and
                                                                                             19
        Patent Applications Filed
1. Hughes, C. Patek, S. and Kovatchev B. "Method and System for Improving
   the Accuracy of Continuous Glucose Sensors Using Insulin Delivery
   Observation in Diabetes”
2. Hughes, C. Patek, S. and Kovatchev B. "Method and System for the Safety
   Analysis and Supervision of Insulin Pump Action and other Modes of Insulin
   Delivery”




                                                                           20
              Other Tech Transfer
1. Handoff of care tool (developed by MINDSET trainees Sledd, Devoge,
   Springs, Brantley and Meth and mentors Bass and Borowitz): Used daily
   by the UVa Health System Departments of Pediatrics and Internal Medicine
   and soon, Family Medicine. System helping to inform the requirements for
   the functionality of a similar tool to be integrated into the EPIC EMR
   implementation.
2. New epinephrine auto-injector (developed by Intelliject, Inc. and evaluated
   in two studies by MINDSET trainees Hugine and Wang and mentor
   Guerlain) is in the FDA approval process as a new drug delivery system
3. Virginia Prostate Exam Simulator (developed and evaluated by MINDSET
   trainees Wang, Rigsbee, Lee, Carson, Rivest, and Baumgart and
   mentors Gerling, Martin and Childress) is being licensed.




                                                                            21
       Curriculum Development
Offered SYS 7097: “Systems Engineering and Medical Informatics
Case Study Seminar on Management of Hyperglycemia in the ICU”.
•Designed to be the first in a series of “Case Study”
courses, each of which will:
   – provide a vehicle for bringing researchers in engineering and
     medicine together for in-depth study of a health-related topic,
   – create the opportunity to learn from the diverse perspectives of
     researchers in different fields and
   – foster innovative solutions to challenging problems.


•Formed a student Education Committee:
   – To provide input on educational activities and help with their
     organization, such as invited speakers, case study seminars,
     tours, tutorials, and poster sessions

                                                                        22
      Marketing and Recruiting
• Created a Director of Recruiting:
   – Executive Committee Member (G. Gerling) in charge of tracking
     openings, project opportunities, and managing recruitment of
     trainees
• Formed a student Marketing and Reporting Committee:
   – To design and publish a tri-annual newsletter and to help with
     tracking metrics for the MINDSET program
• Formed a student Website Committee:
   – To design, publish and maintain the MINDSET website




                                                                      23
                       Social Activities
• Formed a student Social Committee:
   – To plan and organize celebrations, get-togethers and side trips
     at meetings




 At the Virginia Tech Highway Test Track, Blacksburg   Annual badminton & barbeque party


                                                                                       24
             Program Tracking
• Created a Director of Budgets:
   – Executive Committee Member (E. Bass) in charge of tracking
     budgets and accounts


• Collecting and formatting data to inform program
  evaluation




                                                                  25
New Funding




              26
   Expanded Role of Division of
       Clinical Informatics
• New faculty lines and support staff
   – Will be hiring in the next year
• Additional space
   – Including workspace for trainees in the health center and a
     usability testing laboratory




                                                                   27
          Summary of Year 3
• Program maturing:
  – Publications
  – Graduations
  – Distributed management structure across students
    and faculty
  – Case Study Seminar
  – Development of Metrics
  – New faculty, students, projects and funding




                                                       28
             Goals for Year 4
• Continue to grow
• Market the program internally and externally
• Write successful renewal to NLM




                                                 29
                          3rd Annual Review
                          Agenda

11:30-12:00   Lunch
12:00-12:10   Welcome and Intros
12:10-12:45   Annual Progress Report (Guerlain)
12:45-1:30    Student Presentations (Lesniak, Baumgart)
1:30 - 2:15   Posters (outside health sciences library)
2:15 - 2:45   Diabetes Research Center (Patek)
2:45-3:05     Students and advisory board discussion
              (without exec committee)
3:05-3:25     Advisory Board finalizes recommendations
3:25-3:45     Group discussion (All)
3:45          Adjourn