Research Grant Application Form

Project Number For Deanship of Research Use Title Page Date Submitted Day Month Year Jordan University of Science and Technology Research Fund Application Form VISION OF DEANSHIP OF RESEARCH “Outstanding Research and Development University” General Guideline TYPES OF UNIVERSITY FUNDED RESEARCH PROJECTS 1. a. b. The University funds the following types of research: Research related to the interests of the faculty of graduate studies. This type of funded projects includes Master and PhD thesis research. Research related to the interest of faculty members. This type of research includes projects funded by: deanship of research; public and private organizations, and international funding agencies. FUNDING RESEARCH PROJECTS 2. 3. 4. 5. The objective of funding projects is to help researchers among faculty members at the University to conduct their research activities at the Jordan University of Science and Technology. The duration of the project funded by the deanship of research is two years maximum. The principal investigator of the project should be a holder of a PhD degree (or an equivalent degree in his/her specialty). Funding could cover the cost of employing a research assistant, research equipments, research consumables and national travels. It does not cover participation in conferences or purchasing computers except in exceptional cases and subject to the approval of the president of the university. An annual report shall be submitted to the Deanship of Research giving details on the progress of the project. A ceiling for funding research project shall be specified in the light of the annual research budget by the Deanship of Research AIMS OF THE DEANSHIP OF RESEARCH To enhance the University’s national reputation as a leading research university and to establish a higher international profile for its research activities. 9. To drive in and sustain an active research culture that fosters high achievements, encourages innovation and contributes to teaching excellences. 10. To increase the attractiveness and standing of the university as an institution with a reputation for high quality scientific research of practical benefit to stakeholders. 8. 6. 7. Deanship of Research Page 1 of 18 11/22/2007 Title of Proposed Project (Brief descriptive title. Give prominence to keywords.) Programmable CFOA-Based Signal Conditioner for Medical Ultrasound Transducers Type of Fund Being Applied For (Select one) √ Faculty Member Research Grant Thesis Oriented Research Grant Collaborative and Competitive Research Grant √ Collab Are You Applying as Member of a Registered Research Group Yes No Title of Research Group Signature of Group Coordinator…………………….…………………………Date………………… Principal Investigator Academic Rank Associate Professor Dr. Mashhour Bani Amer Faculty of Engineering/ Biomedical Engineering 02-7201000 Ext. 22105 E-mail: m-b-amer@just.edu.jo Full Name and Signature College and Department Telephone, Fax, E-Mail Co- Principal Investigator(s) (Add more names if necessary) Position Full Name and Signature College and Department Telephone, Fax, E-Mail, Position Full Name and Signature College and Department Telephone, Fax, E-Mail, Start Date September 2007 Duration 12 months Deanship of Research Page 2 of 18 11/22/2007 Title of Proposed Project Programmable CFOA-Based Signal Conditioner for Medical Ultrasound Transducers I. STATEMENT OF THE PROBLEM Ultrasound transducers are widely used in medical field for both diagnostic and therapeutic purposes. The ultrasound transducer is a device that converts ac oscillations into acoustical vibrations and converts the reflected back echoes into electrical oscillations. The electrical signals produced by the transducer in response to received echoes are sent to the signal conditioner for processing. It performs amplification, compensation, filteration and other functions on these signals. The ultrasound signal attenuates as it penetrates the biological tissues, so reflections from an object deeper in the tissue is weaker than it would be from the same object closer to the surface. The value of attenuation depends mainly on the acoustical impedance of biological tissues and operating frequency of used transducer. Typical diagnostic ultrasound transducers operate in the frequency range higher than 1 MHz while therapeutic ultrasound transducers used in focused ultrasound use lower frequency than diagnostic ultrasound (from 250 kHz to 2000 kHz), but significantly higher energies. To overcome this problem, the amplifier must have a gain that varies with time (time-gain compensation or depth-gain compensation). The conventional signal conditioners for the available ultrasound transducers have many drawbacks. The first drawback is that they are based on voltage feedback op-amp (VFOA). Thus, they have limited bandwidth (typically about 1 MHz) which is unsuitable for most of medical ultrasound transducers because most of them have operating frequency higher than 1 MHz. Furthermore, the VFOA have small slew rate (typically about 50 V/µs) which is not sufficient for processing high frequency signals. The second drawback is that they are not digitally programmable which makes them suitable only for limited number of transducers (not universal). Accordingly, the need remains for a signal conditioner that overcomes the drawbacks of conventional signal conditioners for ultrasound transducers. To achieve this goal, a programmable current feedback operational amplifier (CFOA) based signal conditioner will be designed and evaluated. The expected features of this conditioner are that it will have better performance than the conventional signal conditioner in terms of power consumption, gain and cut-off frequency and it can be adapted to all commonly used medical ultrasound transducers. Integration of this conditioner on a single chip will minimize its dimensions and make it suitable for portable medical sonographic scanners. II. PROJECT GOALS AND OBJECTIVES The main goal of this project is to design and evaluate a novel programmable CFOA-based signal conditioner for medical ultrasound transducer. The objectives are: 1. Design of a low noise and ultra low power programmable gain CFOA-amplifier 2. Design of a CFOA-filter with digitally tunable cut-off frequency 3. Design of a time gain compensation amplifier. III. INTRODUCTION 1. REVIEW AND ANALYSIS OF RELATED WORK Ultrasound is widely utilized diagnostic and therapeutic medical procedure that uses high frequency sound waves. Diagnostic ultrasound has significant clinical applications in cardiology, endocrinology, gastroenterology, gynecology, obstetrics, ophthalmology, urology, and musculoskeletal tendons [1], [2]. Therapeutic applications use ultrasound to bring heat or agitation into the body. Therapeutic ultrasound may be used to: clean teeth in dental hygiene, generate regional heating in biological tissue (such as occupational therapy, physical therapy and cancer treatment), and generate highly localized energy to treat tumors and break up kidney stones [3], [4]. The most important part of any diagnostic or therapeutic ultrasonic equipment is the transducer. Medical ultrasonography usually use one or more ultrasound transducers to send acoustic pulses into biological tissues and organs where part of this sound wave is reflected back to the transducers and is detected as an echo [5], [6]. The time it takes for the echo to travel back to the transducer is measured and used to calculate the depth of the tissue interface causing the echo. The return sound wave vibrates the transducer and the transducer turns the vibrations into electrical pulses that travel to the signal conditioner Deanship of Research Page 3 of 18 11/22/2007 where they are processed before their digitization and transformation into image. Thus, the analog processing components of the signal conditioner are key elements in determining the overall ultrasound system performance. The performance parameters of the signal conditioner building blocks affect significantly the diagnostic performance of medical ultrasound system. This is because the characteristics of designed blocks define the limits on ultrasound system performance. For example if noise and distortion have been introduced, it will not be easy to remove them which implies that weak design of signal conditioner will result in a weak performance of the ultrasound equipment and in consequence wrong diagnostic performance. Furthermore, in spite of transducer type (single-element transducer or multi-element (linear- or phased- array transducer) it requires programmable signal conditioner concerning power consumption, gain and cut-off frequency. A typical ultrasound system is illustrated in Fig. 1. As shown in this Figure, the signal conditioner is the key part of the ultrasound system, which typically consists of low noise amplifier, time-gain compensation amplifier and high frequency active filters. Fig.1 Block diagram of medical ultrasound system with conventional signal conditioner and multi-element ultrasound transducer. Deanship of Research Page 4 of 18 11/22/2007 Fig.2 Block diagram of medical ultrasound system with the proposed programmable CFOA-based signal conditioner and multi-element ultrasound transducer. Comparing both the conventional and proposed signal conditioners shown in Figures 1 and 2, it can be concluded that the proposed one will have better performance parameters than the conventional one. This is because the proposed conditioner is programmable one concerning gain, cut-off frequency, power consumption and adaptable for different types of ultrasound transducers. The conventional conditioner has fixed gain for each element in the amplifier array and fixed cut-off frequency for each element in the filter array. Furthermore, the proposed signal conditioner will be designed using current feedback operational amplifier (CFOA) instead of VFOA or discrete transistors [7]-[9]. The CFOA offers many advantages over the VFOA such as wide-bandwidth greater than several hundred MHz, high slew rates in the order of 3000V/ µs, high linearity (low distortion with large signals at high frequencies) and high flexibility in adjusting bandwidth and stability [10] – [12]. Thus, due to use of CFOA, the proposed ultrasound conditioner will have also better specifications than the conventional one in terms of bandwidth, slew rate, distortion, and stability. In addition to noise reduction, the CFOA-based filter with digitally programmable cutoff frequency is added at the end stage of the proposed conditioner. Deanship of Research Page 5 of 18 11/22/2007 2. SIGNIFICANCE OF WORK The ultrasound systems have very wide applications in medicine. The signal conditioner is part of almost all ultrasonic systems. Thus, designing a signal conditioner with better performance parameters than the conventional ones, will improve the quality of the available ultrasonic systems and in consequence improves their diagnostic performance. IV. PLAN OF WORK 1. METHODOLOGY: A signal conditioner for processing the ultrasound signals will be developed and experimentally tested taking into consideration the safety requirements of biomedical devices. The main building blocks of this conditioner are low noise digitally programmable gain CFAO-based amplifier, time gain compensation circuit, and digitally tunable CFOA-based active filter. Evaluation of the developed ultrasound conditioner is very important issue. The testing procedure will be started by testing the functionality and parameters of each building block of this conditioner and then, the whole conditioning system will be tested. The signal conditioner will be evaluated using the following criteria: functionality richness, reusability, adaptability, performance, and safety. If these evaluation criteria pass without flaw, the designed conditioner will have met all the performance requirements and will be ready for the next step towards applications. 2. LOCATION AND SAFETY CONSIDERATIONS: The research will be conducted in Amman Private University in Jordan and the safety consideration of medical systems will be considered during the realization of this project. 3. AVAILABLE RESOURCES: Lab. Equipments: Oscilloscope, multimeter and functional generators Educational Data acquisition Card Resources Requirements To conduct this research the following items are required: Ultrasound transducer Water Bath with ultrasound reflector High-resolution data acquisition card Electronic devices (RLC components, CFOA, voltage-mode op-amps, microcontroller, evaluation kit, digital resistances) 4. EXPECTED RESULTS/OUTPUTS: The expected output of this project is a prototype for programmable CFOA-based signal conditioner for ultrasound transducers that has better performance characteristics than the conventional conditioners. Deanship of Research Page 6 of 18 11/22/2007 V. REFERENCES [1]. A. Hossak and B. A. Auld, Improving the characteristics of a transducer using multiple piezoelectric layers, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Vol. 40, pp. 131 – 139, 1993. [2]. C. Kasai et al., Real –time two-dimensional blood flow imaging using an auto-correlation technique, IEEE Transactions on Sonics and Ultrasonics, Vol.7, pp. 458-464, 1985. [3]. J. A. Hossack, Extended focal depth imaging for medical ultrasound, Proceedings of IEEE Ultrasonic Symposium, pp. 1535-1540,1996. [4]. J. U. Kluiwstra, R. J. McGough and C. A. Cain, Therapeutic ultrasound phased arrays: practical consideration and design strategies, IEEE Ultrasonics Symposium, pp. 1277 – 1280, 1997. [5]. D. A. Christensen, Ultrasound Bioinstrumentation, New York: Wiley, 1988 [6]. A. Goldstein, Ultrasonic imaging, in J. G. Webster (ed.), Encyclopedia of Medical Devices and Instrumentation, New York: Wiley, pp.2803-2823, 1988. [7]. E. Brun, A dual current feedback op-amp in CMOS Technology, Analog Integrated Circuits and Signal Processing, Vol. 5, pp. 213 – 217, 1994. [8]. A. Payne, and C. Toumazou, High frequency self-compensation of current-feedback devices, International Symposium on Circuits and Systems, pp. 1376 -1379, 1992 [9]. G. Palmisano and G. Palumbo, High-drive CMOS current amplifier, IEEE Journal of Solid-State Circuits, Vol. 33, No. 2, 1998. [10] C. M. Chang et al., Novel universal current-mode filters using unity gain cells, International Journal of Electronics, Vol. 88, No. 1, pp. 23 – 30, 2001. [11]. S. Franco, Design with operational amplifiers and analog integrated circuits, McGraw- Hill, pp. 162 – 173, 1988 [12]. M. Bani Amer, New High Frequency CFOA-Based Differential Integrator, Third IEEE International Conference on Systems, Signals and Devices (SSD'05), Sousse, March 22-25, 2005. Deanship of Research Page 7 of 18 11/22/2007 VI. DISCUSS ANY RELATED ETHICAL ISSUES The project does not involve using animals, humans, or samples from animals and humans. Thus, no need for special approvals to conduct this research. VII. THE ROLE OF THE INVESTIGATOR(S) Area of Contribution to Project Design and Evaluation of a programmable CFOA-Based Signal Conditioner for Medical Ultrasound Transducers. The main tasks that will realized by the principal investigator are summarized below in the "Project Schedule" No. Name of Investigator Dr. Mashhour Bani Amer 1. 2. 3. 4. VIII. PROJECT SCHEDULE From MM/YY 09/2007 Phases of project implementation No. 1 2 3 4 5 Task Design of a low noise and ultra low power programmable gain CFOA-amplifier Design of a CFOA-filter with digitally tunable cut-off frequency Design of a time gain compensation amplifier 02/2008 Evaluation of the signal conditioning system 04/2008 Documentation and Publication 07/2008 08/2008 2 Months 06/2008 3 Months 03/2008 2 Months To MM/YY 11/2007 Duration (Months) 3 Months 12/2007 01/2008 2 Months Deanship of Research Page 8 of 18 11/22/2007 IX. BUDGET OF THE PROPOSED RESEARCH Priority of Item Item Amount Required 1 = Max Priority 2 = Second Priority 3 = Least Priority 1 Budget should be in Jordanian Dinnars (JD). Personnel (research assistant) 600 Small Equipment (list) Ultrasound transducer High Resolution DAQ Water Bath with ultrasound reflector 700 1500 1000 1 1 1 Testing and Analysis - Consumables (list) Electronic devices (RLC components, CFOA, voltage-mode op-amps, microcontroller, evaluation kit, digital resistances) 600 1 Publications Travel (local) Other Items (Please Details) 100 - Software(s) Total= - 4500 JD Deanship of Research Page 9 of 18 11/22/2007 X. JUSTIFICATION OF BUDGET Item Justification To assist in conducting the experimental work Justify each item listed in the budget in the previous section. Research Assistant Ultrasound transducer High Resolution DAQ Water Bath with ultrasound reflector To provide experimental testing and evaluation of the prototype of proposed CFOAbased signal conditioner Electronic Devices Travel To design the circuitry of the proposed signal conditioner To cover the expenses of local travels that will be needed during the evaluation process of the ultrasound systems and their signal conditioners available in different hospitals and companies. Deanship of Research Page 10 of 18 11/22/2007 XI. ON-GOING FUNDING FROM JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY FOR PRENCIPAL INVESTIGATOR Source of Funds Amount of Funds Time Commitment (Hrs/Week) Please list funded projects No. Project Title No on-going funding projects from Jordan University of Science and Technology Deanship of Research Page 11 of 18 11/22/2007 ‫‪Appendix A‬‬ ‫אن א‬ ‫ﻣﻜﻴﻒ ﺇﺷﺎﺭﺍﺕ ﻗﺎﺑﻞ ﻟﻠﱪﳎﺔ ﻟﻠﻤﺠﺴﺎﺕ ﺍﻟﻄﺒﻴﺔ ﺍﻟﻔﻮﻕ ﺻﻮﺗﻴﺔ‬ ‫:‬ ‫א‬ ‫ﺗﻌﺘﱪ ﺍﻷﺟﻬﺰﺓ ﺍﻟﻄﺒﻴﺔ ﺍﻟﻔﻮﻕ ﺻﻮﺗﻴﺔ ﻣﻦ ﺃﻫﻢ ﺍﻷﺟﻬﺰﺓ ﺍﻟﻌﻼﺟﻴﺔ ﻭﺍﻟﺘﺸﺨﻴﺼﻴﺔ ﰲ ﺍﳌﺴﺘﺸﻔﻴﺎﺕ ﻭﺍﳌﺮﺍﻓﻖ ﺍﻟﺼﺤﻴﺔ ﺍﳌﺨﺘﻠﻔﺔ. ﻫﺬﺍ ﻭﻳﻌﺘﱪ ﳎﺲ ﺍﻹﺷﺎﺭﺍﺕ ﺍﻟﻔﻮﻕ ﺻﻮﺗﻴﺔ ﺃﺣﺪ‬ ‫ﺍﻟﻌﻨﺎﺻﺮ ﺍﻷﺳﺎﺳﻴﺔ ﰲ ﻫﺬﻩ ﺍﻷﺟﻬﺰﺓ، ﻭﺍﻟﺬﻱ ﻳﺮﺗﺒﻂ ﺃﻳﻀﺎ ﻣﻊ ﻣﻜﻴﻒ ﺇﺷﺎﺭﺍﺕ ﺷﺒﻴﻬﺔ ﺧﺎﺹ ﺑﻪ ﻳﻘﻮﻡ ﺑﺘﻀﺨﻴﻢ ﻭﺗﺮﺷﻴﺢ ﺍﻹﺷﺎﺭﺍﺕ ﺍﻟﻌﺎﺋﺪﺓ ﻣﻦ ﺍ‪‬ﺲ.‬ ‫ﺗﻜﻤﻦ ﺳﻴﺌﺔ ﻫﺬﻩ ﺍﳌﻜﻴﻔﺎﺕ ﺑﺄﻥ ﺍﻟﻮﺣﺪﺍﺕ ﺍﻟﺮﺋﻴﺴﻴﺔ ‪‬ﺎ ﻭﻫﻲ: ﺍﳌﻀﺨﺎﺕ ﻭﺍﳌﺮﺷﺤﺎﺕ، ﻏﲑ ﻗﺎﺑﻠﺔ ﻟﻠﱪﳎﺔ ﺭﻗﻤﻴﺎ ﳑﺎ ﻳﺘﻄﻠﺐ ﺗﺼﻤﻴﻢ ﻣﻜﻴﻒ ﺷﺒﻴﻪ ﻟﻜﻞ ﻧﻮﻉ ﻣﻦ ﺃﻧﻮﺍﻉ‬ ‫ﺍ‪‬ﺴﺎﺕ ﺍﻟﻔﻮﻕ ﺻﻮﺗﻴﺔ. ﻭﻋﻠﻴﻪ ﻓﺈﻥ ﻫﺬﺍ ﺍﳌﺸﺮﻭﻉ ﻳﻬﺪﻑ ﻟﺘﺤﺴﲔ ﺍﻟﻌﻨﺎﺻﺮ ﺍﻟﺘﻘﻨﻴﺔ ﳍﺬﻩ ﺍﳌﻜﻴﻔﺎﺕ ﻭﺫﻟﻚ ﻣﻦ ﺧﻼﻝ ﺍﻗﺘﺮﺍﺡ ﺗﺼﻤﻴﻢ ﻗﺎﺑﻞ ﻟﻠﱪﳎﺔ ﺭﻗﻤﻴﺎ ﻗﺎﺋﻢ ﻋﻠﻰ‬ ‫ﺍﺳﺘﺨﺪﺍﻡ ﺍﳌﻀﺨﻢ ﺍﻟﻌﻤﻠﻴﺎﰐ ﺍﻟﺘﻴﺎﺭﻱ ﻭﺍﻟﺬﻱ ﳝﺘﺎﺯ ﺑﺴﻌﺔ ﺍﳌﺪﻯ ﺍﻟﺘﺮﺩﺩﻱ، ﺳﺮﻋﺔ ﺍﻻﺳﺘﺠﺎﺑﺔ، ﺍﺳﺘﻘﺮﺍﺭ ﻋﺎﱄ ﻭﺍﺳﺘﻬﻼﻙ ﻃﺎﻗﺔ ﻗﻠﻴﻞ ﺟﺪﺍ ﺑﺪﻻ ﻣﻦ ﺍﳌﻀﺨﻢ ﺍﻟﻌﻤﻠﻴﺎﰐ‬ ‫ﺍﳉﻬﺪﻱ.‬ ‫‪Deanship of Research‬‬ ‫81 ‪Page 12 of‬‬ ‫7002/22/11‬ Appendix B C.V. Format for Principal Investigator and Co-Investigators (Two pages maximum, material should be related to submitted project.) Title and Name Dr. Mashhour Bani Amer , Associate Professor Specialty Biomedical Engineering Department / College: Biomedical Engineering/ Faculty of Engineering Summary of Experience Associate Professor of Biomedical Eng., Biomedical Eng. Dept., (JUST), Assistant Professor of Biomedical Eng., Biomedical Eng. Dept., (JUST), Assistant Professor of Biomedical Eng., Electrical Eng. Dept., (Al-Isra University), Courses Taught:: o o o o o o o o o o o o o Biomedical Sensors Biomedical Instrumentation 1 Biomedical Systems Analysis Diagnostic Techniques Special Topics in Biomedical Engineering Medical Electronics 1 (For BME Students) Medical Electronics 2 (For BME Students) Digital Electronics Electronics 1 (For EE Students) Electronics 2 (For EE students) Electronics 2 for Computer Engineering Students Biomedical Instrumentation Lab. 1 Electronics Labs. 1 & 2 September 19, 2006 – till now 2000– Sep. 18, 2006 1994 - 2000 List of Publications M. Bani Amer, Mathematical Model of Chloride Concentration in Human Blood, Journal of Medical Engineering and Technology, Vol. 30, No.1, January/February 2006. M. Bani Amer, New High Frequency CFOA-Based Differential Integrator, Third IEEE International Conference on Systems, Signals and Devices (SSD'05), Sousse, March 22-25, 2005. M. Bani Amer, Samer Ammari, Basheer Alshamiri, New Optical Glucose Sensor, IASTED International Conference on Biomedical Engineering (BioMED 2005), February 2005. M. S. Ibbini, M. A. Masadeh, and M. Bani Amer, A Semiclosed- Loop Optimal Control System for Blood Glucose Level in Diabetes, Journal of Medical Engineering and Technology,Vol.28, No.5, pp.189-196, September/ October 2004. M. Bani Amer, Novel Design of Bioelectric Amplifier with Minimized Magnitude and Phase Errors, Journal of Electronics, Vol. 18, No. 3, pp. 242-254, July 2001. M. S. Ibbini, M. S. Masadeh, and M. M. Bani Amer, A Fuzzy Logic Control Technique For blood Glucose Level In Diabetics, International Conference on Biomechanics, pp. 77-80, June 2003, Greece. Deanship of Research Page 13 of 18 11/22/2007 M. Bani Amer, Metrological Assessment of the Analyzers for the Measurement of Blood Gasometric Parameters, CAM’93 Conference on Biomedical Measurements, pp. 113-120, 1993. J. Fraczek, M. Bani Amer and P. Walichiewicz, Analysis of Homogeneity of the Results of Biomedical Measurements in Clinical Laboratories, CAM’93 Conference on Biomedical Measurements, pp. 53-54, 1993. M. Bani Amer, A Reliable and Accurate Capnometer for Medical Use, The 2nd IEEE Conference on Measurement Systems and Networks, Poland, 1992. Appendix C DEPARTMENT EVALUATION AND RECOMENDATION Research Project Evaluation: Evaluation Item Research methodology Research objectives Research originality Research contribution Research applicability and relevance An overall evaluation Excellent Very good Good Weak Chairman of Department Research Committee.................................................................... Signature.................................................................................................................................................. Date...................................................................................................................... Recommendation: _________________________________________________________________________________ Recommendations of the Department Council Approved Disapproved Signature-------------------------------------------------Date-------------------------------------------------------------- Appendix E Deanship of Research Page 14 of 18 11/22/2007 FACULTY RECOMMENDATION _________________________________________________________________________________ Recommendation of the Faculty Research Committee: Chairman of Faculty Research Committee: Signature-----------------------------Date-------------------- _________________________________________________________________________________ Recommendation of the Dean of the Faculty Approved Disapproved Signature--------------------------------------------Date------------------------------------------------------------------- _________________________________________________________________________________ Deanship of Research Page 15 of 18 11/22/2007 Appendix F INSTITUTIONAL RESEARCH BOARD (IRB) APPROVAL _________________________________________________________________________________ University Review Committee for Research on Humans (Any research on humans should be approved by this committee before approving this research work). Approved Approved on conditions (Use an additional sheet for details) Disapproved Chairman of University Review Committee for Research on Humans -------------------------------Signature------------------------Date -----------------------_________________________________________________________________________________ Deanship of Research Page 16 of 18 11/22/2007 Appendix G ANIMAL CARE AND USE COMMITTEE (ACUC) APPROVAL _________________________________________________________________________________ University Review Committee for Research on Animals (Any research on animals should be approved by this committee before approving this research work). Approved Approved on conditions (Use an additional sheet for details) Disapproved Chairman of University Review Committee for Research on Animals -------------------------------Signature------------------------Date -----------------------_________________________________________________________________________________ Deanship of Research Page 17 of 18 11/22/2007 Appendix H UNIVERSITY RESEARCH COMMITTEE RECOMENDATION _________________________________________________________________________________ University Research Committee: Approved & Amount of grant -----------------------------JD Disapproved Postponed Directed to --------------------------------------------------------Dean of Research---------------------------- Signature----------------------Date -------------------------- _________________________________________________________________________________ Deanship of Research Page 18 of 18 11/22/2007