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Collaborating Family Cancer Centres - Centres

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					Dear reaDers                                 individually carry only a small risk of breast
                                             cancer. But the risks add up and become
australian researchers and clinicians        very significant in women that happen to
became very excited a few months ago         inherit changes in several of these genes.
about the discovery of five new genes        Some of these genes have been known for
that increase the risk of breast cancer.     years, but until now were not suspected
The work was carried out by a large          of being involved in familial breast cancer.
consortium of international researchers,     Because they each contribute only a
led by Douglas easton and his colleagues     relatively small risk of disease, they are
in Cambridge UK, who used data and           known as polygenes and have individual
DNa samples collected from women             names such as FGFR2, TNRC9, MAP3K1,
in many countries. australia was well        LSP1 and CASP8. Researchers in kConFab
represented. My research group at            who are part of this international research
the Queensland Institute of Medical          investigation are planning experiments
research, Professor John Hopper              to look at the biological and clinical
from the University of Melbourne and         implication of changes in these new
Professor David Bowtell from the Peter       polygenes. We hope that within a few
MacCallum Cancer Centre (using data          years a test will be developed to identify
and biological samples collected by          women in the population at the highest
kConFab, the australian Breast Cancer        risk of breast cancer (regardless of their
Family study and australian Ovarian          family history) and offer more intensive
Cancer study) all contributed to this        screening to detect breast tumours early.
international effort.
                                             We have added a reminder on page 5 about
What are the new findings?                   contacting us if you are having surgery, as
We have known for many years about the       we are still keen to collect donations of all
two major breast cancer genes - BRCA1 and    types of tissue.
BRCA2. About 30% of families with many       Finally, a big-thank you to all kConFab
cases of breast and ovarian cancer carry     participants and family members who
mutations in one or other of these genes.    donated art work for the Friends of
But what causes cancer in the rest of the    kConFab “Breast Cheque” art show which
families? Douglas Easton and colleagues      was held at The Menzies art brand gallery
in Cambridge decided to search the
                                             South Yarra, in September 2007. We have a
human genome for genes that were not
                                             story about this event on page 5 but your
as powerful as BRCA1 or BRCA2 but could
                                             generous support was greatly appreciated
nevertheless contribute to cancer. Because                                                    Published by kConFab,
                                             by the whole kConFab team. An amazing
of knowledge and techniques that have                                                         Peter MacCallum Cancer Centre,
                                             $80,000 was raised. It was a privilege to see
come from the Human Genome Project,
                                             how gifted you all are and how important         St Andrew’s Place East
Doug Easton could compare the genomes
                                             art is to so many of you.                        Melbourne, Vic 3002
of cancer patients with those of people
without cancer. They identified many genes   Yours sincerely                                  Tel: 03 9656 1542
that were different in the two groups.
                                             Georgia Chenevix-Trench                          Website: http://www.kconfab.org
Further work showed that these genes         Chair, kConFab Executive committee
researCH                                             IMPACT uPdATes
UPDaTes                                              - (Identification of Men with a genetic predisposition to ProstAte
                                                     Cancer: Targeted screening in BRCA1 and BRCA2 mutation
Faults (mutations)                                   carriers and controls)
in the breast cancer
gene BrCa2 can                                       Dr. Gillian Mitchell, Peter MacCallum           Melbourne Hospital in Victoria, through
cause prostate                                       Cancer Institute and Dr. Geoff
                                                     Lindeman royal Melbourne Hospital,
                                                                                                     the South Australia Genetics service/
                                                                                                     Repatriation Hospital in South Australia
cancer in men                                        Melbourne.                                      and Westmead Hospital in Sydney. We
kConFab researchers based at The                                                                     have so far recruited over 60 Australian
                                                     You may remember that in the last
Peter MacCallum Cancer Hospital and                                                                  men, which is over a third of the world-
                                                     kConFab newsletter, we highlighted a
The University of Melbourne have                                                                     wide recruitment to date. Two men
                                                     study about prostate cancer screening
demonstrated for the first time that                                                                 have already been found to have early
                                                     that was about to start recruiting. It is
mutations in the BRCA2 gene are                                                                      prostate cancer and have undergone
                                                     called the IMPACT study and its full title
directly responsible for most of the                                                                 the appropriate treatment for this.
                                                     is Identification of Men with a genetic
prostate cancers that arise in male                  predisposition to ProstAte Cancer:              We will be writing to all the men in
mutation carriers. However, there                    Targeted screening in BRCA1 and BRCA2           kConFab who are potentially eligible for
did not appear to be an association                  mutation carriers and controls.                 the study inviting them to take part.
between mutations in BRCA1 and the
development of prostate cancer.                      This is an international study that was set     But if you are interested, you do not
                                                     up because men who are from families            have to wait for the invitation and you
This kConFab study demonstrates the                  where there is a mutation (fault) in            can call Heather Thorne on 1800 221
importance of men’s family cancer                    the BRCA1 or BRCA2 genes causing an             894 or Melbourne 03 9656 1542 or
history, especially if they belong to a              increased risk of breast and/or ovarian         email familial.cancer@petermac.org to
family with a known BRCA2 mutation                   cancer may be at increased risk of prostate     register your interest at any time.
and have cases of breast and/or ovarian              cancer if they have inherited the same
cancer. Future research may provide                  gene change. The risk of prostate cancer

                                                                                                      Upcoming
evidence to support intensified                      for men with the BRCA1 mutation are less
screening of men at increased genetic
risk of prostate (please see IMPACT the
                                                     than for men with a BRCA2 mutation.             This study is looking to
article directly below).
The title and contributing authors of
                                                     This study is looking to see if yearly
                                                     screening with a Psa blood test is a
                                                     useful way to detect prostate cancer in
                                                                                                      Events: test is
                                                                                                       see if yearly screening
                                                                                                     with a PSA blood
this work to be published soon in the                men from these families. To answer this          Familial Cancer 2008:
American Cancer Research journal is:                 question, we are comparing the results of        a useful way to detect
                                                                                                      research and Practice
Loss of heterozygosity at the BrCa2                  PSA tests in men who have been found to
locus detected by MLPa is common                     carry the family BRCA1 or BRCA2 mutation                      cancer in men
                                                                                                     prostate meeting of kConFab,
                                                                                                      a Combined
                                                     against the men who do not carry their
in prostate cancers from men with
a germline BrCa2 mutation. Amber                     family mutation. To take part in the study           from these families.
                                                                                                      australian Ovarian Cancer study
                                                                                                      (aOCs), the Family Cancer Clinics
J. Willems1, Sarah-Jane Dawson2,                     men have to be in a family where there is         of australia and New Zealand
Hema Samaratunga3, Alessandro                        a known alteration the BRCA1 or BRCA2
De Luca4, Yoland C. Antill2, kConFab                 gene. Men who are interested can take             Venue:
Investigators1, John L. Hopper5, and                 part whether or not they know their own
                                                                                                       Couran Cove Island Resort,
Heather J. Thorne1.                                  genetic test result.
                                                                                                       Queensland
                                                     Participation in this study involves a yearly
                                                                                                       Dates:
Kathleen Cuningham Consortium for Research           visit to a study hospital to complete a
into Familial Breast Cancer (kConFab), Research      questionnaire and have a sample of blood          19th – 22nd August 2008
Department Peter MacCallum Cancer Centre,            and urine taken. If the PSA blood test is
Locked Bag 1, A’Beckett St, Victoria, Australia;                                                       Contact:
                                                     higher than the cut off level, then the
2
   Department of Haematology and Medical
Oncology, Peter MacCallum Cancer Centre,             man will be referred to a local urologist          heather.thorne@petermac.org for
Locked Bag 1, A’Beckett St, Victoria, Australia; 3   for further investigation. Subsequent             further details or view the conference
Department of Anatomical Pathology, Sullivan         treatment will depend on the results              updates on the kConFab home page
Nicolaides Pathology, 134 Whitmore Street,
Taringa, Queensland; Australia, 4 Centre for         of the PSA test and any prostate biopsy           at http://www.kconfab.org
Translational and Applied Genomics, British          done by the urologist.
Columbia Cancer Agency, Vancouver, BC,
Canada; 5 Centre for Molecular, Environmental,       We are now in a position to open the
Genetic and Analytic Epidemiology, School of         study throughout the country. So far
Population Health, The University of Melbourne,      we have opened the study at the Peter
Victoria, Australia.
                                                     MacCallum Cancer Centre and Royal
PARPi (PARP inhibitoR) UPdAte                                                                     Around the
By Dr Clare Scott, Royal Melbourne              a member of your family who has a              clinics – updAtes
Hospital and Dr Gillian Mitchell, The Peter     BrCa1 or BrCa2 mutation (fault) and
                                                                                               Westmead Familial Cancer service
MacCallum Cancer Centre, Melbourne.             has breast cancer that has returned
                                                and may need more treatment, then              welcomes a new genetic counsellor,
We would like to give you a brief                                                              Michelle Howson to the team.
                                                they may be able to take part in this
update about the treatment study
                                                trial. If you or a member of your family is    The Familial Cancer Registry of Western
targeting women with breast or
                                                interested in hearing more about this trial,   Australia currently has 517 registrants
ovarian cancer with a mutation in the
                                                then please contact Heather Thorne on          214 who are included in the Registry for
BrCa1 or BrCa2 gene.
                                                1800 221 894 or Melbourne 03 9656 1542,        reasons related to breast cancer, with the
Last year we wrote a short article about        who will put you in touch with the doctors     remaining 303 being registered because
a new drug, an inhibitor of an enzyme           running this trial.                            of hereditary colon or other familial
called PARP, in a tablet form that is now                                                      conditions. The Registry is a voluntary
                                                _________________________________
under investigation for women who have                                                         service that accepts people with known
a BRCA1 or BRCA2 mutation and who have          are there other genes that interact with       mutations or who are from families that
recurrent breast or ovarian cancer. The         BrCa1 and BrCa2 in the development             require high -surveillance.
breast or ovarian cancers in these women        of breast cancer? The answer appears
are expected to be very vulnerable to           to be Yes.                                     The Registry assists with managing
this new type of chemotherapy (PARPi)                                                          surveillance by keeping records of reports
                                                By Dr Georgia Chenevix-Trench,                 and providing a reminder service to those
because of the presence of the BRCA1 or
                                                Queensland Institute for Medical               whose surveillance is overdue. When
BRCA2 mutation. The study is available
                                                Research, Brisbane.                            a report is received, it is scrutinized and
to women whose cancer has recurred
and who require additional therapy.             My laboratory is involved in a large           checked against personal and family
                                                international consortium know as CIMBA         history. As scientific progress is made or
Two international clinical trials were                                                         family circumstances change, surveillance
                                                (Consortium of Investigators of Modifiers of
opened last year, one for women with                                                           recommendations may also change and
                                                BRCA1 and BRCA2). This group has pooled
recurrent ovarian cancer and one for                                                           members are notified.
                                                data on the lifestyle of almost 20,000
women with breast cancer. The ovarian
                                                people from around the world (including        Breast surveillance in Perth is well organised.
cancer study opened and closed within a
                                                participants from 1000 kConFab families),      Those with mutations (or those from high
few months, as there were many women
                                                who are known to carry a BRCA1 or              risk families) are seen annually in a high-
who were eligible for the study. In
                                                BRCA2 mutation. Our research has shown         risk, one-stop-shop clinic conducted
Australia we enrolled 20% of the women
                                                that changes in some of the polygenes          across two major metropolitan teaching
participating in the study worldwide. We
                                                identified by the Breast Cancer Association    hospitals. These clinics offer specialist
are hoping that the results of the study
                                                Consortium (see this edition’s editorial),     care and, if need be, access to imaging
will be very exciting and the early results
                                                when present with a BRCA1 or BRCA2             techniques such as MRI.
will be presented at a large international
                                                mutation appear to increase the likelihood
conference in May this year. We will keep                                                      The Registry works in collaboration with
                                                that breast cancer will develop. In the
you updated about the results in the next                                                      the high risk clinics, Genetic Services of
                                                future, information of this type may help a
edition of the newsletter.                                                                     WA and kConFab to help provide personal,
                                                women decide if and when she wants to
The study for women with breast cancer          have prophylactic surgery to reduce her        appropriate and timely services to those
is still open and available, so if there is     risk of breast cancer.                         with an increased risk of breast cancer.




  Pink Blush…..
  In March 2007 Crystal, the daughter of one of our kConFab families,
  was married in a pink wedding gown to honour the three generations
  of women with breast cancer in her family. The gorgeous gown was
  perfectly matched in colour to the National Breast Cancer Foundations
  Pink Ribbon. Guest donated $2 into a beautiful pink beaded box
  that had been hand made by Crystal’s mother Julie-Anne. The box
  contained a National Breast Cancer Foundation Pink Ribbon that was
  worn by all guests on the night. All proceeds raised were donated
  to the National Breast Cancer Foundation, who distributes funds
  Australia-wide to research projects like kConFab.
  Crystal and Chris on her wedding day
  Photograph generously provided by Jeremy Byrnes:
  jeremy@jeremybyrnes.com www.jeremybyrnes.com
Book Review:
singing the Life – the story of a family
in the shadow of cancer
By elizabeth Bryan; published by
Vermilion
This title alone will probably strike some
chords with kConFab participants, and
the book is likely to be of interest to many.
Elizabeth (Libby) Bryan has known since
she received a letter out of the blue from                                                        The Mothers Day Classic will be held
a cousin in 1975 that her family had many                                                         nationally on sunday 11 May in
cases of ovarian cancer. Even back then,                                                          capital cities and regional areas.
the letter suggested that the women in                                                            Last year, the Mothers Day Classic
the family might want to consider having                                                          attracted more than 50,000 participants
their ovaries removed to reduce their risk                                                        nationwide and raised over $800,000
of cancer, although the writer was not sure                                                       for its beneficiary, the National Breast
whether the susceptibility could be passed                                                        Cancer Foundation. The total raised by
through a male, Libby’s father.                                                                   the event for breast cancer research
For the next decade or so Libby was busy                                                          since 1998 is more than $3 million.
with her professional life as a very successful                                                   Who organises the event?
paediatrician and expert in multiple births,
but her personal life was affected by her         and still no one knows if her cancer was        The events are organised and presented
inability to have children. Her love of           related to her BRCA1 mutation status, or        by Women in Super - a national
children is demonstrated by the many              just incidental. She realised immediately       network of women working in the
references to her 14 godchildren and 16           that the prognosis for this cancer is very      superannuation industry.
grand-godchildren. When Libby finally had         poor, and so the implications very serious,
                                                                                                  The vast majority of the people who help
her ovaries removed to reduce her cancer          and the second half of the book is much
                                                                                                  to put together the Mothers Day Classic
risk, after her sister was diagnosed with         more reflective, as she describes her own
                                                                                                  are volunteers. They give their time each
ovarian cancer, she felt a sense of relief. .     surgery and chemotherapy, and thoughts
                                                                                                  year as a way of actively contributing to
                                                  about life and death.
The first half of the book tells the moving                                                       the fight against breast cancer.
story of her family since that letter in 1975,    Despite the content, and Libby’s uncertain
                                                                                                  This initiative was inspired by the
including one sister’s death from ovarian         future, this book is funny and informative,
                                                                                                  knowledge that research is gradually
cancer, another’s development of breast           as well as of course very sad in parts. Libby
                                                                                                  improving the survival rate of the one
cancer, her father’s death from prostate          discusses the genetics of breast cancer in a
                                                                                                  in 8 women who will be diagnosed with
cancer, the identification of a mutation          very simple way, and leaves open many of
                                                                                                  breast cancer during their life. Improving
in the BRCA1 gene in their family, and in         the ethical issues, particularly about how
                                                                                                  the quality of life of those with breast
Libby herself, and her own prophylactic           to inform the younger members of the
                                                                                                  cancer is a valuable and rewarding
oophorectomy and mastectomy. Libby                family about their risks and options. She
                                                                                                  investment into our community.
describes her sister Bunny’s death and the        also tries to put the cancers in her family
mixed reactions of everyone, particularly         into perspective, not least against the         Where does the money raised go?
Bunny’s young children, to the tragedy.           background of the bipolar disorder which
                                                                                                  All proceeds from the Mothers Day
Despite a professional lifetime of helping        also runs in her family and directly, or
                                                                                                  Classic are donated to the National
grieving parents, Libby found she was ill         indirectly, claimed the lives of her mother
                                                                                                  Breast Cancer Foundation, a not for
equipped to deal with such a personal             and her niece. We recommend this
                                                                                                  profit organisation that promotes and
experience in her young and traumatised           book highly to anyone with a personal or
                                                                                                  supports research into breast cancer
nieces. She also discusses many of the            professional interest in familial cancer.
                                                                                                  prevention and treatment.
practical issues around her mastectomy,
                                                  Editors note: We write with great sadness to
and its ‘minor’ complications that did not                                                        How can I be involved?
                                                  tell you that Libby passed away on Thursday,
seem so minor to her at the time.
                                                  21st February 2008. Despite some very           In Brisbane, Melbourne, Adelaide,
By the time Libby was told that she herself       happy times and superb medical care,            Hobart, Sydney, Perth, Canberra and
was a carrier, having inherited the mutation      she had been going gently downhill for          regional areas you can participate in
from her father, she was so expecting the         some weeks and died peacefully at home          the Mothers Day Classic Walk and Run.
news that it came as little surprise - even       as she had hoped, looking out at the Black      It’s a fun day for everyone involved with
though she knew before the test that              Mountains. We extend our condolences to         food, activities and kids entertainment
she only had a 50% risk of carrying the           her family and close kConFab friends.           available. You can enter as an individual,
mutation. What did come as a surprise,                                                            family or part of a team.
                                                  Available via Amazon or Random
however, was her diagnosis of pancreatic
                                                  House Australia.                                To register visit -
cancer in 2005. Pancreatic cancer is not
                                                                                                  www.mothersdayclassic.org
usually associated with BRCA1 mutations,          http://www.randomhouse.com.au/
                                                •   Please remember that fresh tissue              your help with this.
   Messages                                         specimens, normal and cancer
                                                    of all tissue types, obtained at
                                                                                                   • Please notify kConFab if, at any time,
                                                                                                   you prefer not to have more contact

   from the                                         surgery are extremely valuable
                                                    for our research. In addition to the
                                                    tissue collections, sometimes, in the     •
                                                                                                   with our study
                                                                                                   Please tell your research nurse if you

   kConFab                                          course of breast or ovarian cancer,
                                                    women experience the build up
                                                                                              •
                                                                                                   change your address
                                                                                                   are there other family members

   team:
                                                    of fluid in their abdomen (this fluid
                                                                                                   eligible to join kConFab?
                                                    is called ascites) or lungs (pleural
                                                    effusion). The ovarian or breast               -   Once a family has been
   To keep kConFab running smoothly,                cancer cells in these fluids can be                counselled at a Family
   we would greatly appreciate if you               used in our research studies. If you               Cancer Clinic about a
   would remember the following:                    find yourself needing to have ascites              genetic (fault) mutation in
                                                    or lung fluid drained at any time,                 the family, additional family
                                                    we would greatly appreciate being                  members may become eligible
   •   Because we send information to you           contacted by either yourself or your                for recruitment into the
       by mail, it is very important to keep        medical staff in advance, so that we               kConFab study.
       your contact details up to date.             can arrange to collect any fluid not
       We may even ask you to send                  required for diagnostic use. Our               -   Once a family member, female
       us the name of another contact               team would make all the necessary                  and male turns 18 years of age
       person, in case we are unable to find        arrangements.                                      they may also be eligible to be
       you. Please use the toll free number                                                            recruited into the kConFab study
                                                •   It is very important that we are
       to pass on these updates 1 800 221                                                          Please call one of our research
       894 and speak to Heather or ring             notified of any new cases of cancer
                                                    in your family. Research relies on             nurses (see contact list at the end of
       your local kConFab research nurse to                                                        this newsletter) if you would like to
       inform them of any surgery planned           accurate and up-to date information
                                                    about the cancers in each of our               confirm if other family members are
       for treatment or prevention.                                                                eligible for recruitment.
                                                    participating families. We appreciate




The friends of kConFab
                                                                                                  the artists involved. We hope you enjoyed
                                                                                                  viewing your work in such a wonderful
                                                                                                  venue – we certainly did!
“Breast Cheque” art show, september 2007                                                          If you would like to hold a fundraising
                                                                                                  function for breast cancer research, please
The Friends of kConFab main fundraising         Thank you to the Friends of kConFab for the       contact the kConFab office on 1 800 221
event for 2007, in partnership with the         work they put into organising this event,         894 or 03 9656 1542 as we will be able
National Breast Cancer Foundation,              Rod and Carolyn Menzies for the donation          to assist you with the organisation of your
was an art exhibition and auction               of their gallery, access to their excellent       event and provide copies of the kConFab
in september as a lead up to Breast             staff and for the donation of art works           “Who’s at Risk” information brochure that
Cancer Month.                                   from their personal collection for auction.       describes our national research work
100% of all funds raised will be directed       Thanks also to media personality Ms Suzi          and how our funds are managed by the
towards our national research efforts.          Wilks for making the opening speech.              National Breast Cancer Foundation. all
We were very fortunate in securing the          Finally, there would not have been an art         funds raised by the Friends of kConFab
sensational Menzies art brand gallery from      show without the generous donations of            will be used for research so we can reach
Rod and Carolyn Menzies, Darling Street         artwork, so a special thank you to all of         our long-term goals.
South Yarra, Melbourne for this event.
kConFab wrote to many of our breast
cancer survivors in Australia inviting any
of our artists or art enthusiasts to consider
donating an existing artwork (painting,
photography, sculpture or glass work) for
this exhibition and auction. In addition to
art works, we also included brief stories in
the exhibition catalogue demonstrating
how art has helped women cope with a
diagnosis of breast cancer or with breast
cancer in the family. The response to our
request was amazing. We had on display
and for auction 120 art works from kConFab
family members, clinicians and scientists.
Collaborating Family Cancer Centres
Melbourne                                 st Vincent’s Hospital                       Tasmania
                                          Family Cancer Clinic
Familial Cancer Centre                    Darlinghurst, 2010                          The royal Hobart Hospital
Peter MacCallum Cancer Institute          Contact Dr Robyn Ward or Ms Rachel          The Lauceston General Hospital
St Andrews Place                          Williams                                    The North West regional Hospital,
East Melbourne, 3002                      Phone: 02 8382 3395                         Bernie
Contact: Ms Mary-Anne Young                                                           Contact: Dr Jo Burke
Phone: 03 9656 1199                       The John Hunter Hospital                    Royal Hobart Hospital
kConFab research nurse: Tina Thorpe       Hunter Valley, NSW                          Phone: 03 6222 8296
Phone: 03 9656 1903                       Contact: Dr Tracey Dudding                  kConFab research nurse: Tina Thorpe
                                          Phone: 02 4985 3132                         Phone: 03 9656 1903
royal Melbourne Hospital                  KConFab research nurse: Helen Conlon
Familial Cancer Centre                    Phone: 02 9382 2607                         Auckland – New Zealand
Parkville, 3050
Contact: Dr Geoffrey Lindeman             Brisbane                                    Northern regional Genetics services
Phone: 03 9342 7151                                                                   auckland Hospital
kConFab research nurse: Tina Thorpe       Queensland Clinical Genetics service        Auckland, New Zealand
Phone: 03 9342 4257                       royal Children’s Hospital                   Phone 0800 476 123 ext 7232
                                          Bramston Terrace                            Family Cancer Clinic Staff
Victorian Clinical Genetics service       Herston, 4029                               NZ local call 0800 476 123, international
Monash Medical Centre                     Contact: Dr Michael Gattas                  64 9 307 4949 EXT 5530
Clayton                                   Phone 07 3636 1686
Contact: Dr Marion Harris                 kConFab research nurse: Vicki Fennelly or   Wellington – New Zealand
Phone: 03 9594 2026                       Allison Wicht
kConFab research nurse: Tina Thorpe       Phone : 07 3636 5200                        Central and southern regional
Phone: 03 9656 1903                                                                   Genetics services Wellington Hospital
                                          Adelaide                                    Wellington South
Sydney                                                                                Contact: Dr Alexa Kidd
                                          south australian Clinical Genetics          Phone 64 4 385 5310
Familial Cancer service                   services                                    Phone International 64 9 307 4949 EXT
Westmead Hospital                         Women’s and Children’s Hospital             5530
Westmead, 2145                            North Adelaide, 5006                        NZ local call 0800 476 123
Contact: Assoc. Prof. Judy Kirk           Contact: Dr Graeme Suthers
Phone: 02 9845 6947                       Phone: 08 8161 6995
kConFab research nurse: Rachel Sinclair
                                                                                      kConFab Manager
                                          kConFab research nurse: Meryl Altree        Heather Thorne
Phone: 02 9845 6845                       Phone: 08 8161 6821                         3rd Floor Research Department
                                                                                      Peter MacCallum Cancer Centre
Prince of Wales Hospital                  Perth                                       East Melbourne, 3002
Hereditary Cancer Clinic
                                                                                      Phone: 03 9656 1542
High Street                               Genetic services of Western australia       Toll free through out Australia: 1800 221
Randwick, 2031                            King edward Memorial Hospital               894
Contact: Dr Kathy Tucker                  374 Bagot Road                              Email: heather.thorne@petermac.org
Phone: 02 9382 2577                       Subiaco, 6008
kConFab research nurse: Helen Conlon      Contact: Dr Ian Walpole or Professor Jack   A donation to kConFab from Global
Phone: 02 9382 2607                       Goldblatt                                   Health www.global-health.com has
                                          Phone 08 9340 1525                          assisted with the publication costs of this
st George Community Hospital              kConFab research nurse: Anna Nash           newsletter.
Hereditary Cancer Clinic                  Phone: 08 9340 1610
Kogarah, 2217                                                                         • Graphic Design
Contact: Dr Kathy Tucker                                                                Michael De Lai Design (03) 9386 7242
Phone: 02 9382 2577                                                                   • Preparation • Print • Logistics
kConFab research nurse: Helen Conlon                                                    Mystique (03) 9764 9489
Phone: 02 9382 2607

				
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