Student-Fellowship-Guidelines-June-2007 by lsy121925


									                              STUDENT RESEARCH FELLOWSHIP AWARD


This program offers financial support for students to spend time performing research on topics relevant to
inflammatory bowel disease for a minimum of ten weeks.


To stimulate interest in research careers in inflammatory bowel disease by providing salary support for
research projects.


Candidates may be undergraduate, medical or graduate students (not yet engaged in thesis research) in
accredited institutions within the United States. Candidates may not hold similar salary support from other


Up to 16 Student Research Fellowship Awards per year at $2,500 each will be available for full-time
research with a mentor investigating a subject relevant to inflammatory bowel disease. The duration of the
project is a minimum of ten weeks. Awards are made payable to the institution (not the individual) where the
research will be conducted. No indirect costs are allowed. A complete financial statement and scientific
progress report are due September 1, the completion date of the project. All publications arising from work
funded by this project must acknowledge support of the Crohn's & Colitis Foundation of America Student
Research Fellowship Award.

Grantees who do not fulfill all obligations of the CCFA award are prohibited from applying for
additional CCFA awards.


For this application, "mentor" is defined as the person who is the head of the laboratory where the candidate
will be trained, and who will be responsible for the candidate's research experience. The mentor must be a
faculty member who directs a research project highly relevant to the study of inflammatory bowel disease at
an accredited institution. Mentor may not be a relative of the applicant and may not work in their lab.


Awardees will be selected based on novelty, feasibility and significance of the proposal, attributes of the
candidate, the record of the mentor, evidence of institutional commitment and the laboratory environment.


A committee composed of members of the CCFA Research Training Awards Committee will review the
proposals and select the awardees.

Application deadlines:          March 15
Awards begin:                   on or about June 15


Print or type responses. Attach additional information and provide signatures as requested. Be sure to
include all required information for the award for which you are applying. Attach separate typed pages for all
additional information using one inch margins. Put your full name (last name, first name) and the name of
the award in the upper right hand corner of each page.

Applications should be collated in the following order:

1. Cover page (form provided)

2. Abstract of proposed research and description of project in scientific and lay terms (form provided)


Scientific Summary of Project: Self-explanatory.

Description of Project in Lay Terms: (found in application forms pg. 3) Please provide a statement in
simplified language, no more than one-half page, containing:

        o    What question will this project attempt to answer?
        o    Why is this question important?
        o    What is the study design?

    Check one CCFA scientific priority that is addressed by your project.
    Check sheet of “Challenges in IBD Research” and Pediatric Challenges in IBD” can be found on
     page 3 of forms.

This statement will be evaluated as part of your application as well as used to inform the
foundation's National Board of Trustees and the general public of the nature of this work.

     This section must be written in language that is easily understandable to (6 - 7 grade reading
                                                                                   th  th

     Define all scientific terms. Words like “pathogenesis” or “cytokines” might be common words to you,
        but not necessarily to lay persons.
        Template for writing the lay summary is on page 3

Use separate pages to provide the following items:

3. Research Plan Description: Must include the aims of the research protocols, rationale of the investigation,
   importance of the study and the methods of procedures. Limit to 2-3 pages including one page for

4. Facilities and Equipment: Describe (list laboratory location, equipment, support staff, clinical facilities).
   Limit to one page.

5. Applicant's Curriculum Vitae: The applicant should:
  a) describe previous research experience;
  b) list any publications;
 c) list academic and/or professional awards.

6. Mentor's Statement: The mentor should:
  a) describe the student and the benefits of this experience, including the student's role in the study;
  b) estimate the portion of the study that the student will be able to complete during the period of the
  c) state the number of students who will be in the laboratory, concurrent with this candidate;
  d) describe the mentor's training record. Limit to 1-2 pages.

7. Mentor's curriculum vitae: Limit to two pages (2-page, biosketch format)


The application must be signed and dated by the applicant, the mentor, the sponsor and a financial officer of
the institution. These signatures signify understanding of and compliance with the policies set forth by the
CCFA regarding the Student Research Fellowship Award.

                           TEMPLATE FOR WRITING LAY SUMMARY

Investigator:            Burrill Bernard Crohn, MD
                         Mount Sinai Hospital
Project:                 Gender differences in growth in pediatric patients with Crohn’s disease
Type of Award:           Student Research Fellowship Award

Description: Growth failure is a unique and important problem for children with IBD. The exact
causes of growth failure, and how best to treat them, is a pressing need. In children with Crohn’s
disease, boys and girls differ in disease severity and growth failure. That is, female patients tend to
have more severe clinical disease but don’t suffer from growth failure, while male patients tend to
have less severe clinical disease and suffer from growth failure. Understanding the reasons for
these differences could provide new clues on the reasons for disease severity and growth affects of
IBD, and how better to treat them. This project tests whether sex hormones (estrogen in females,
testosterone in males) act differently on the function of hormones controlling growth (growth
hormone itself, Insulin-like Growth Factor-1 [IGF-1], and the pathway linking them). This project
will study 90 pediatric Crohn’s patients under the age of 17, matched to a control group of patients
with short stature alone (unrelated to Crohn’s disease), and determine whether disease activity
affects growth hormone/IGF-1 levels, and how this affects growth in kids with Crohn’s.

Significance: If successful, this project will establish whether a combination of sex and growth
hormone levels can be used to predict growth failure. This information could help identify children
with different biologic types of growth failure, and guide the development of more targeted
treatments to correct them.

Category: Pediatric Challenges #1 (Growth and Bone Health)


All inventions or intellectual property (“Property”) that results from support, in whole or in part, of research,
training grants or awards from the Crohn’s & Colitis Foundation of America (“CCFA”) must be reported in
writing at the earliest possible time to CCFA. The grantee institution agrees to notify CCFA within a
reasonable time, preferably within 30 days, of receiving an invention disclosure or other notice indicating
existence of a Property and to notify CCFA immediately of the decision to apply for letters of patent or other
legal protection for the Property. Each grantee institution further agrees to seriously consider, in good faith,
any comments, suggestions or objections that CCFA may have concerning such applications or other legal
protection. CCFA agrees to keep all information confidential and not to release any information relating to
such inventions, intellectual property or applications for protection to any third party, except as specifically
set forth below or upon written agreement with the grantee institution, which consent can not be
unreasonable withheld. All patenting expenses or intellectual property application expenses shall be borne
by the grantee institution.

Title to all Property shall reside with the grantee institution to the extent that such title is claimed by the
institution under its institutional patent policy or procedure. If a grantee institution has no established,
institutional patent policy or procedure for administering inventions or intellectual property, or if the
institutional patent policy or procedure does not claim rights for the institution or individual inventor, then
CCFA shall have the right to determine the disposition of the Property rights in accordance with the
provisions set forth below.

Distribution of income derived from any Property, which might include equity disposition, shall be shared by
the grantee institution and CCFA on mutually agreeable terms, such terms to be determined as soon as
practicable, preferably prior to any licensing or commercial exploitation of the Property, and in any event no
later than 6 months after first receipt of income. Such distribution shall be guided by the principle that
CCFA’s proportion of the income shall be reasonably related to CCFA’s proportion of support for the
research leading to the Property. The grantee institution agrees to notify CCFA within a reasonable time of
beginning negotiations with potential licensees and to notify CCFA upon execution of any license or other
agreement to commercialize the Property and provide a copy of the license or other agreement to CCFA.

If any Property is made with or results from the joint support of CCFA and another organization, that
organization, the grantee institution, and CCFA will confer, in good faith, to arrive at a mutually satisfactory
disposition of the Property rights guided by the principle that distributions of income be made in proportion to
each party’s contribution of support for the research leading to the Property.

No patent, patent application or other type of protection for a Property shall be abandoned without first
notifying CCFA and giving CCFA reasonable opportunity to take title to the Property.

The grantee institution agrees that when it licenses a Property, it will obligate the licensees as follows: The
licensee shall agree to exert its best efforts to commercialize or cause to be commercialized the Property as
rapidly as practical, consistent with sound and reasonable business practices and judgment. In the event
the licensee has failed to commercialize the Property within the number of years determined to be
reasonable for that Property, and minimally a three-year period, the grantee institution, upon conferring with
CCFA, shall have the right to convert an exclusive license to a non-exclusive license or terminate an existing
non-exclusive license with such licensee. If the licensee or grantee institution has an ongoing and active
research, development, manufacturing, marketing or licensing program as appropriately directed toward the
production and sale of the Property, the same would be deemed to be sufficient evidence that the licensee
or grantee institution has commercialized the Property.

The grantee institution acknowledges complete responsibility for all aspects of the research,
investigation, funding and administration of and in connection with the grant award. To the extent permitted
under the international, federal, state and local laws which govern the grantee institution, the grantee
institution shall indemnify and hold CCFA harmless from and against
any and all costs, losses or expenses, including reasonable attorneys’ fees, that CCFA may incur by reason
of the grantee institution’s negligence or misconduct or any third-party claim arising out of or in connection
with the project which is the subject of the grant.

Grantee institution shall be required to maintain adequate liability insurance comparable to coverage held by
institutions of similar size and nature, covering the employees, officers and agents of CCFA for the duration

of the project. CCFA may request to be provided certificates evidencing the insurance coverage at any time
during the term of the project.

CCFA reserves the right to public acknowledgment for Property resulting from research supported by CCFA.
However, CCFA’s name and logo may not be used in association with any Property without the prior written
approval of CCFA.

CCFA shall have use of the Property without payment of royalties or license fees solely for the use by CCFA
for its own intramural or public education purposes, but not for any of its grantee institutions.

Awardees and grantee institutions are responsible for ensuring that there are no inconsistencies in their
consulting or business agreements that conflict with this policy.


Send one Master, two hard copies and one copy on a disk or CD in either Microsoft Word (Windows) or PDF
format (note; only the CD or DISK will be distributed to the reviewers and the complete application must be
compiled as one document file – not multiple files.) Paper copies that do not have a disk or CD will be
                                Crohn’s & Colitis Foundation of America
                                Research and Scientific Programs Department
                                386 Park Avenue South – 17 Floor
                                New York, NY 10016-8804

All applications must be received by 5:00pm Eastern Standard Time on the submission deadline. Early
submission is encouraged. Paper copies that do not have a disk or CD will be rejected.

If the deadlines fall on a weekend or national holiday, the submission deadline will be extended to
the next business day.

                            OR FORMAT MAY NOT BE REVIEWED


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