Download - Prostate Supporter March 2008 by hjkuiw354


                                                         The newsletter of the Prostate Cancer Support
                                                             and Action Groups of South Australia

 March 2008                                                          in brief...

National conference
                                                                                                      The first Tool Box
                                                                                                      session for the RAH
                                                                                                      men’s health initiaitve is
                                                                                                      on Wednesday, March

outlines 2008 plans
                                                                                                      12, in the RAH Robson
                                                                                                      Lecture Theatre, noon
                                                                                                      to 12.45pm. Cynthia
                                                                                                      Edwards from The
T   HE PCFA Support and
    Advocacy Annual Con-
ference in Sydney on Febru-
                                                                                                      Cancer Council and
                                                                                                      Kathy Pietris from the
ary 20 and 21 was attended by                                                                         National Bowel Cancer
Ian Fisk and Dean Wall from                                                                           Screening Program will
South Australia.                                                                                      talk about Men & Bowel
                                                                                                      Cancer. All are welcome;
 The official minutes are not                                                                          please RSVP by phoning
yet available, though agenda                                                                          8222 5193.
items included a review of the
SAC task list, CEO report by                                                                          Reg Mayes has been
Andrew Giles, a report on the                                                                         home under the care
2008 Ambassador Program by                                                                            of Amy since Feb 6.
Jo Fairbairn, introducing new    Pictured at the national conference: Paul Redman (PCFA               He is still very alert and
PCFFA managers Paul Red-         Support Group Services Manager), Ian Fisk (SA), John Allen           cheeky, is walking with
man (Support Group Services      (NSW), Max Shub (Vic), Karen Rendell (WA), Daryl Hyland              the aid of a stick, but
Manager) and Anne Gilhooly       (Qld), Dr Jim Clough (ACT), Dean Wall (SA), Bill McHugh              has lost considerable
(Communications Manager),        (Qld and Chairman of SAC) and Lionel Foote (Qld).                    weight. A report on
planning for SAC activities      Fact Sheet Draft #2 explained      but eventually all groups in is
in 2008, and a presentation on   by Paul Redman (who spent          Australia will be added.          updated occasionally.
trials by Dr Cleola Anderiesz,   many years in the insurance                                          Contributions to these
                                                                     Reports were presented on
National Manager, Research,      business); outlining the role of                                     newsletters from all
                                                                    the Prostate Cancer Support
Cancer Australia.                State Chapters; and a website                                        Support Groups and
                                                                    Handbook and the DVD librar-
 Bill McHugh was re-elected      demonstration of www.pcfa.         ies, which are both progressing   members are welcomed;
as chairman of the SAC. At present information     well. More outcomes from the      send items and images
 Other topics of interest were
                                 has only been added for the        conference will be published      by email to prostate-
a Support Group Insurance
                                 Queensland support groups,         in coming newsletters.  

New McLaren Vale support group commences
T   HE McLaren Districts
    Prostate Cancer Support
Group held its inaugural meet-
                                 Lovell and Carol Pinnock from
                                 the Repat Hospital. They were
                                 followed by Kathriye Strass-
                                                                    unit at RAH, and Anne Col-
                                                                    lins, who told the group of her
                                                                    story from the perspective of
                                                                                                      ing at 7pm in the hospital ad-
                                                                                                      ministration building. Local
                                                                                                      GP Dr Graham Lovell will
ing on September 6, 2007, in     nick from Cancer Council SA        the partner of a sufferer.        deliver a presentation on diet,
the administration building at   and Jeff Roberts, who spoke         At the previous group meet-      exercise and the importance of
the McLaren Vale & Districts     about prostate cancer support      ing, Dr Denby Steel, Urologist    regular check ups.
War Memorial Hospital.           groups in general.                 was the guest speaker.             Anybody wishing further de-
 Speakers on the first night       Since then the group has been      The next McLaren Districts       tails about this group should
were Brent Frewen from Pros-     addressed by Dr Raghu Gow-         Group meeting is scheduled        contact Bryan Hearn by phon-
tateSA, local GP Dr Graham       da from the Brachytherapy          for Thursday March 20, start-     ing 8323 7924.

      The Prostate Cancer Foundation of Australia freecall hotline is 1800 22 00 99
                      or visit the website
Page 2               
                            Prostate Cancer Action Group

 COMING                    Awareness meetings
                           enjoy further success
 The next Awareness        The Prostate Cancer Action Group has started the new
 Meeting will be held      year with heartening respose to its continuing program
 in the RSL Hall,
 Apex Park, Stirling       of awareness meetings, as Trevor Hunt reports.
 on April 23. Meeting
 details have not yet
 been confirmed,
                           T   HE most recent prostate
                               cancer awareness meet-
                           ing, held at Mt Barker, on
                                                             This was the fourth such
                                                            awareness meeting conducted
                                                            in the Adelaide Hills area, all
                                                                                               foreshore on Sunday, March
                                                                                               16. As with previous years,
                                                                                               the Action Group will present
 though the hall is
                           November 22 last year, was       of which have been sponsored       an information stall stocked
 not available until
                           an encouraging success for       and promoted by the Freema-        with an extensive array of
 7.30pm. Therefore
                           the Prostate Cancer Action       sons Lodges in the Hills.          pamphlets and booklets bear-
 the meeting will have
                           Group.                            These four meetings have at-      ing information about prostate
 to commence from
                            An audience of 79 people at-    tracted a total audience of over   cancer.
 about 7.30pm, which
 is a little later than    tended, coming from a wide       300 people, and the involve-        The Action Group has been
 usual.                    variety of areas throughout      ment of the Freemasons is          represented at every MAN
                           the Adelaide Hills, and cov-     very much appreciated by the       ALIVE! event, and has no-
 MARCH MEETING             ered age groups from 40 to 79    Action Group.                      ticed the increased interest in
 The next Prostate         years.                            The series will continue with     our stall.
 Cancer Action Group         From this audience, 31 eval-   an April Awareness Meeting          This year, we will be part of a
 meeting will be held      uation forms were returned,      in Stirling; see the Coming        new innovation for this event,
 in the upstairs meet-     and of these, only eight men     Events column at left for full     the Man Alive! Trail – a par-
 ing room, Cancer          had been diagnosed with pros-    details.                           ticipatory activity that requires
 Council SA building,      tate cancer.                                                        people to have a free raffle
 202 Greenhill Road,                                                                           entry form stamped by every
                            It was heartening to know       SPEAKING
 Eastwood, at 5.30pm                                                                           Community Agency/Group
                           that the meeting had success-    ENGAGEMENTS
 on Tuesday March                                                                              stall on the Trail. It is expected
                           fully attracted so many inter-
 11. Enter via the back                                     TWO members of the Action          that our stall will be quite busy
                           ested people who have little
 stairs. New members                                        Group involved in the Ambas-       because of our inclusion in
                           awareness or knowledge of
 are most welcome.                                          sadorʼs programme have re-         this activity.
                           the disease.
                                                            cently been involved in more        The Man Alive! event will be
                            Most respondents rated the      speaking engagements – and
 For more information                                                                          hosted by Channel 7ʼs Graeme
                           meeting as “very” or “some-      would like further opportuni-
 about the Action                                                                              Goodings, and its purpose
                           what helpful”, and most          ties to spead the word.
 Group and its                                                                                 is to promote menʼs health
                           thought the information pro-
 activities, visit the                                       If you know of any group or       and well-being, and celebrate
                           vided by our speakers was ex-
 South Australian                                           organisation that is looking for   menʼs contribution to our com-
                           cellent, or good.
 Prostate Cancer                                            guest speakers on the topic of     munity. Other services avail-
 Action Group’s             Most comments were com-         prostate cancer, please let Ian    able to men at the public event
 dedicated website at      plimentary; we noted only        Fisk or Dean Wall know, as         include a Free Health Check at
 http://www.pcagsa.        two adverse comments about       theyʼd be happy to contribue       one stall.                    the length of the meeting. One   their services.
                           comment noted that it was the                                        In addition to the wide range
 The site has detailed
                           women present in the audience                                       of health services and com-
 archives of its
                           that asked the questions!        MAN ALIVE!                         munity groups, the event has
 newsletters, containing
                                                                                               a great, quality entertainment
 many informative           It was notable that a health     The Action Groupʼs next           programme, including Afri-
 articles and published    professional in the audience     major effort will be to run a      can drummers, popular Celtic
 research findings          commented that the meeting       stall at the increasingly popu-    rock band The Borderers, and
 about prostate cancer     had improved his knowledge       lar menʼs health event, MAN        other fun activities. Admission
 and its treatment.        of prostate cancer.              ALIVE!, at the Semaphore           is free.

    The Prostate Cancer Foundation of Australia freecall hotline is 1800 22 00 99
                    or visit the website
                                                                                Page 3
  Prostate Cancer Support and Awareness: ADELAIDE GROUP

FOR 2008
                             A fresh opportunity
The Adelaide Group
usually meets on the
third Monday of each
                             for us to be inspired
month, in the Park           The Adelaide Group’s first meeting for 2008 featured guest
View Room of the             speaker Derrick McManus, who detailed his fight for survival.
Fullarton Park Centre,
411 Fullarton Rd,
Fullarton.                   D    errick McManus, a mem-
                                  ber of the SA Police force
                             for 28 years, was awarded the
                                                               of fire for three hours, while
                                                               the gunfight continued around
                                                               him. Incredibly, he recounts
                                                                                                  and other immediate medical
                                                                                                  assistance which saved him
                                                                                                  from the brink of death. He
                             inaugural SA Police Bravery       that he had many positive          says these medicos were the
Monday March 17th
                             Medal in 1989, and has a long     thoughts about family, friends     true heroes, along with his
Guest speaker will be
                             history of community involve-     and colleagues while laying in     team who risked their lives to
Ms Judy Brookstrom,
                             ment over 20 years, earning       this desperate position, know-     save his.
Therapist with the
                             him an Australia Day Young        ing that they would soon res-       After a lengthy period of re-
Panic Anxiety Disorder
                             Citizen of the Year Award.        cue him.                           habilitation, in every situation
Association. She has
been conducting               However his speech focused        These positive thoughts, es-      returned to work at the STAR
anxiety programs and         on a siege in the Barossa Val-    pecially about his family, pro-    Division.
information sessions for     ley on May 3, 1994. Sergeant      vided him with a fierce deter-       His presentation captivated
many years.                  McManus, then a member of         mination to survive.               members who attended the
                             the STAR Division, was shot        Sergeant McManus empha-           meeting, as he spoke with
Monday April 21st            14 times with a high-pow-         sized that opportunities present   compassion, humor, was in-
Guest speaker will be        ered semi-automatic weapon.       themselves in every situation,     sightful and exhibited an abil-
Ms Belle Mc Caleb,           With broken bones and sev-        and that we need to recognise      ity to easily relate to people.
naturopath, nutritionist     ered arteries, he lay bleeding    and make the most of them.
                             profusely for three hours be-                                         His messages were espe-
and herbalist at the
                             fore he was rescued.               He remains especially grate-      cially valuable to the group,
Cancer Care Centre
                                                               ful to the Royal Adelaide          including “no matter what the
Naturopathy Clinic,           He remained conscious but        Hospital Retrieval Team who        circumstance, plan to win”,
providing nutritional        was unable to move and laid       placed their own lives at risk     and “success is a matter of
medicine for prostate        on open ground in the field        to provide blood (24 units)        choice”.
cancer support.

Monday May 19th
                             Positive outlook expressed by new members
Guest speaker will be        PETER Woodrow and Peter           nosed with an aggressive pros-     the next year until a radical
Dr Mary Brooksbank,          OʼConnor, new members to          tate cancer which appeared to      prostatectomy was performed,
director of the Palliative   the Adelaide group, told the      be contained within the pros-      followed by continuing fluc-
Care Unit at the Royal       February meeting in some de-      tate (T2 ) with a gleason score    tuations in PSA readings and
Adelaide Hospital.           tail about their journeys with    of eight. Peter had a radical      prescribed medicines.
                             prostate cancer – and how         prostatectomy, in December          Peter says he will discuss his
Monday June 16th             through their ordeals they ex-    2007, and his February PSA         illness with anybody who is
A general discussion         ude a sense of well being, hap-   test indicated a reading of .04.   interested, as it may help oth-
evening concerning           piness and the ability to enjoy   His urologist is quite optimis-    ers with similar problems. “We
Prostate Cancer.             and appreciate life.              tic concerning his long term       are all different and what may
                               Peter Woodrow had been re-      prognosis, and Peter is looking    happen to one person may not
For more information,        tired for two years and had a     forward to getting back on the     necessarily have the same ef-
visit the Adelaide           family history of prostate can-   golf course.                       fect or result on another. We
Group’s dedicated            cer, (father and grandfather).     Peter OʼConnorʼs father and       should listen to each other and
website at www.              During a regular check in         five of his seven siblings had      discuss our concerns with our or           2007, his PSA indicated an el-    died of cancer; in June 2003,      doctors.”
contact President Phil       evated reading from 3.7 to 5.7.   Peter had a blood test that in-    • Peter OʼConnorʼs full treat-
Davis; Phone 82632217        He was referred to a urologist    dicated a PSA reading of 8,        ment story will be published       and after a biopsy was diag-      which contined rising through      in the April newsleteer.
    The Prostate Cancer Foundation of Australia freecall hotline is 1800 22 00 99
                    or visit the website
Page 4           
          City of Onkaparinga Prostate Cancer Support Group

FOR 2008                    Making the group
The Support Group’s
next meeting is being
                            known to politicians
held in the boardroom       Group President John Shields reports a good start for 2008
at Noarlunga                – with increased recognition in the southern community.
Community Hospital,
Alexander Kelly
Drive, Noarlunga, on
Wednesday, March 5
                            T   HE CITY of Onkaparinga
                                Prostate Cancer Support
                            Group was fortunate to be in-
                                                               work, live and play. Ann and
                                                               Dolph Young were present,
                                                               representing the Cancer Sup-
                                                                                                 support group meeting, proved
                                                                                                 yet again to be a great experi-
                                                                                                 ence, being able to hear ev-
at 6.30pm. The guest        vited to morning tea at Artie      port Network-Onkaparinga.         eryone sharing their many and
speaker is Pam Lawton       Fergusonʼs to meet Amanda          This meant that cancer support    varied prostate cancer experi-
from Carers Association     Rishworth MP – the new Fed-        interests were extremely well     ences, and at the same time be-
SA, who will talk about     eral Member for the seat of        represented at the meeting,       ing a fount of information for
Caring & Carer Support.     Kingston, which includes the       with the presence of John and     our visitors and new members,
                            Onkaparinga district.              Phyllis Shields, and Malcolm      including Ken and Frank.
APRIL MEETING:                                                 and Beverley Ellis joining
                             Artie invited representatives                                       INFORMATION DAY
Our guest speaker                                              Artie and Juli Ferguson.
                            from various groups in the Mid                                       AT SEAFORD
for the meeting on
                            South Coast Ward – groups          FEBRUARY MEETING                  A PUBLIC information pre-
April 2 will be Graeme
                            that he works very hard for        ANN and Dolph Young also          sentation on prostate cancer
Goodings, Channel 7
                            – to meet Amanda Rishworth,        joined social worker Jules Van    and the support group will
personality and cancer
                            who told us that she would be      Kekem at the Onkaparinga          be conducted in the Seaford
survivor. This meeting
                            happy to attend future Onkapa-     groupʼs February meeting to       Shopping Centre on Wednes-
will be held in a larger
                            ringa Group meetings, to talk      provide an update on work         day, April 30, from 9am to
room behind the
                            about ways that she can be of      in progress and upcoming          5pm, near Chem Mart, which
cafeteria at Noarlunga
                            assistance with such things as     events, including a menʼs sup-    is a particularly busy shopping
Community Hospital.
                            grants.                            port group, a survivors group,    area. If you can help by being
For more information,        Group president John Shields      a resource information centre     present on that day, it will be
visit the City of           will be inviting her to attend     in the region and the launch of   very much appreciated.
Onkaparinga Support         the groupʼs April meeting,         the Fleurieu Cancer Network.       An information day will also
Group’s dedicated           when Graeme Goodings will           We are going to purchase a       be held at Woodcroft Shopping
website at                  be guest speaker.                  display screen, as discussed      Centre later this year, possibly                The morning tea at Artieʼs        at the Association meeting. It    during September.
                            also provided a good opportu-      is hoped that we may be able       The group will also make in-
• Special thanks is         nity for us to meet other mem-     to obtain a significant discount
extended to the City                                                                             quiries at Aldinga and the Hub
                            bers of our community who          if other groups also commit to    Shopping Centre in Aberfoyle
of Onkaparinga Sup-         are giving of themselves to        purchasing screens.
port Group sponsors:                                                                             Park, to see if it is worthwhile
                            help make the City of Onkapa-       The Round Robin discussion,      for us to have a presence there
Southern Primary            ringa a much better place to
Health Woodcroft,                                              which is always a part of our     also.
Port Noarlunga-Chris-
ties Beach RSL Sub          What do you think of the newsletter?
Branch, Thaxted Park
Golf Club Inc, The          YOUR feedback on the new            It is also our intention for     the     many      community
Original Open Market,       combined newsletter would be       the newsletter to become          organisations within the City
and to all who provide      appreciated – and it could be      a valuable resource in the        of Onkaparinga.
valuable support our        valuable for us in our continued   doctorsʼ     waiting     rooms,    Please phone John Shields on
group – especially the      efforts to make the newsletter     hospital information areas,       8382 6671 with your ideas. If
City of Onkaparinga         interesting, eye catching, and     primary health reception areas,   you could offer help to deliver
Council.                    a publication that everyone        libraries and other local group   some of these newsletters, it
                            looks forward to receiving.        meeting facilities, especially    would be greatly appreciated.

    The Prostate Cancer Foundation of Australia freecall hotline is 1800 22 00 99
                    or visit the website
                                                                                 Page 5
                         Mitcham Prostate Cancer Support Group

Aiming to consolidate                                                                                  COMING EVENTS
                                                                                                       Thursday March 27

support for members
                                                                                                       Speaker will be Dr Peter
                                                                                                       Sutherland – Head of
                                                                                                       Urology, Royal Adelaide
                                                                                                       Hospital. His team of

T    HE Annual          General
     Meeting that marked the
groupʼs first gathering for
                                   Pinnock, urologist Dr J. Titus,
                                   physiotherapist Virginia Gill,
                                   counsellor Darren Hosne and
                                                                     Liason/welcoming member
                                                                     - Roland Harris
                                                                                                       researchers offer trials
                                                                                                       of new drugs and new
                                                                                                       techniques. He has a
                                                                     Promotions officer - Jeff
2008, held on February 28,         Ian Fisk, speaking about the      Roberts (temporary)               special interest in male
looked at strategies to increase   PCFA Ambassador Group. At                                           sexual dysfunction, and
and consolidate meeting            meetings without a speaker,        Following the AGM, Ian Fisk
                                                                                                       pioneered use of the
attendances, with the aim of       DVDs on health related issues     showed a DVD of the PCFA
                                                                                                       DaVinci Robotic Surgical
continuing to provide support      were screened.                    Menʼs Health Promotion
                                                                                                       System for prostatectomy
and fellowship to members                                            Forum held in Adelaide on
                                    2007 was the second year                                           surgery at the RAH. He
and their families, and to                                           October 6, 2007, showing the
                                   where we finished the year                                           has particular expertise
provide quality speakers on                                          presentations of John Oliffe
                                   with a social dinner at the                                         in managing prostate
topics of interest.                                                  and Gary Wittert.
                                   RSL, and it looks as though                                         cancer, vasectomy
 During 2007, attendances at       this may occur annually.           Mitcham Group usually meets      reversal, treatment of
meetings varied considerably,                                        on the fourth Thursday of each    kidney stones and laser
                                    Chairman Terry Harbour,          month, in the Colonel Light
from 13 to well over 30, with                                                                          treatment of prostatic
                                   declared all positions for 2008   Gardens RSL Clubrooms, at 4
a few new faces – including                                                                            obstruction.
                                   vacant. Positions were filled as   Prince George Parade, Colonel
Heinz who, after hearing about     follows:                                                            Thursday April 24
our support group, got in a taxi                                     Light Gardens.
                                                                                                       Dr Samantha Pillay
and came from Semaphore to         Chairman - Terry Harbour          • For further information,        - Consultant Urologist,
be part of the August meeting.     Deputy Chairman - not filled       phone Mitcham group chair         Calvary Hospital, will
 Several excellent speakers        Secretary - Graham Bradley        Terry Harbour on 8271             speak on treating
featured at meetings, including                                      0513, Jeff Roberts on 8277        incontinence after
                                   Treasurer - John
clinical researcher Dr Carole                                        3424 or visit our website         prostate surgery.

               Barossa & Gawler Prostate Cancer Support Group

Spirit of cooperation helps group to progress
T   HE first meeting for 2008
    was attended by 19 mem-
bers, a lively informal gather-
                                   group. Max recently learned
                                   that he failed to satisfy the
                                   necessary criteria for brachy-
                                                                     • When possible, proceedings
                                                                     will be relaxed to encourage
                                                                     informal chat.
                                                                                                       COMING EVENT
ing that encouraged plenty of      therapy treatment – a combi-                                        Tuesday April 22
                                                                     • A portable recorder will be     Meeting from 2pm to
social interaction and shared      nation of age (just over 70),     purchased for use during meet-
health news around dinner          prostate size and PSA (11).                                         4pm at the home of
                                                                     ings, supplanting the need for    Margaret and Robert
tables prepared by hosts Tony      Other members were able to        a minutes secretary.
and Jill Woolley.                  reassure him and explain other                                      Reimann, 29 George St,
                                   treatment options.                • An article will be prepared     Greenock. The meeting
 Alan Hall reported on a tele-                                       for publication in local papers   will focus on nutrition.
conference with Prostate SA         The meeting made several         to coincide with State-wide       Members are asked to
and Cancer Council SA, and a       resolutions based on interim      publicity through television      bring a plate of after-
meeting of group leaders with      committee suggestions:            and The Advertiser. It is an-     noon tea.
PR consultant Karyn Foster.        • The number of meetings          ticipated this campaign will
The Prostate Supporter news-                                                                           • For more information
                                   will be reduced, and some day     boost group membership.           about the Barossa
letter was discussed and ap-       meetings will be held.
proval was unanimous.                                                 • Barossa Health has been ap-    & Gawler Group,
                                   • A roster will be prepared for   proached for support and in-      contact Alan Hall at
 New members Max and Rose-         refreshments organisers.          volvement with the group.
mary were welcomed to the
      The Prostate Cancer Foundation of Australia freecall hotline is 1800 22 00 99
                      or visit the website
Page 6               
    Research findings and news items from around the world
                                                                                                    Submitted by Trevor Hunt

edge to
                           Urine tests lead to more
new cancer
                           accurate diagnoses
                           Unravelling prostate-specific gene data is pointing
are road-testing a new     towards better patient test procedures, as
“in your face” national    researchers report from Michigan in the US.
prostate cancer
awareness campaign.
 The campaign
features information
                           A     N      EXPERIMENTAL
                                 biomarker test devel-
                           oped by researchers at the
                                                                  “We want to develop a test
                                                                 to allow physicians to predict
                                                                 whether their patients have
                                                                                                    underwent prostate biopsy at a
                                                                                                    University of Michigan urol-
                                                                                                    ogy clinic. Among this group,
imploring men to           University of Michigan more           prostate cancer that is so accu-   biopsy results confirmed a di-
have a blood test for      accurately detects prostate           rate a biopsy won’t be needed      agnosis of prostate cancer in
prostate cancer, and       cancer than any other screen-         to rule cancer out,” Chinnai-      138 patients.
the information posters    ing method currently in use,          yan said. “No test can do that      Correlating the urine bio-
will sit right above       according to a study published        now.”                              marker test results with the
every toilet in every      in the February 1 issue of             Chinnaiyan and the Michigan       biopsy data, researchers found
hotel in australia.        Cancer Research, a journal of         researchers developed the test     that, in combination, four of
 The new campaign is       the American Association for          based on their recent finding       the seven biomarkers were
the brainchild of the      Cancer Research.                      that gene fusions (pieces of       significant predictors of pros-
EJ Whitten Foundation       The researchers say a simple         chromosomes that trade places      tate cancer: GOLPH2, which
and the Australian         urine test that screens for the       with each other, causing two       is generally over-expressed
Hotels Association.        presence of four different RNA        genes to stick together) are       in prostate cancer; SPlNK1,
 The foundation will       molecules accurately identi-          common in prostate cancer,         over-expressed in a subset of
spread the word by         fied 80 per cent of patients in a      and by overriding molecular        these cancers; the PCA3 tran-
using men’s toilets        study who were later found to         switches that turn off excess      script expression; and TM-
at pubs to relay           have prostate cancer, and was         growth may affect the caus-        PRSS2:ERG fusion status. Of
the message about          61 per cent effective in ruling       ative factor in some forms of      the seven markers, only PCA3
prostate cancer
                           out disease in other study par-       the disease.                       had been previously reported
directly to men.
                           ticipants.                             In 2005 the researchers iden-     as a diagnostic biomarker.
 “You really have to get    This is far more accurate than       tified a prostate-specific gene       When tested as individual
in their faces,” says      the PSA blood test currently in       called TMPRSS2 which fuses         biomarkers, GOLPH2, PCA3,
Ted Whitten Jr, “so        use worldwide, which can ac-          with either ERG or ETV1, two       and SPINK1 each outper-
where better than in
                           curately detect prostate cancer       genes known to be involved in      formed PSA, which had iden-
the inner sanctum of
that most masculine of
                           in men with the disease but           several types of cancer.           tified all of the men in the
venues.”                   which also identifies many              In 2007, they identified an-       study as potentially positive
                           men with enlarged prostate            other five genes that fuse onto     for prostate cancer.
 Urologist Dr Doug
                           glands who do not develop             ERG or ETV1 to cause pros-          The combination of the four
Travis, president of
                           cancer, researchers say.              tate cancer.                       biomarkers achieved a speci-
the Australian Medical
Association’s Victorian
                            Even the newer PCA3 test,             In the current study, research-   ficity and positive predictive
branch, said it was        which screens for a molecule          ers built upon the PCA3 test       value of greater than 75 per
“extremely important       specific to prostate cancer and        by screening for six additional    cent, which they found to be
for men, when they         is now used in the US and Eu-         biomarkers, including TM-          five perc ent better than use of
are 50 to have the         rope is less precise.                 PRSS2:ERG, as well as mole-        a PCA3 test alone.
blood test for prostate     “Relative to what is out there,      cules generally over-expressed      Chinnaiyan believes any tests
cancer... however, men     this is the best test so far,” said   in prostate cancer, and some       developed and widely tested
in their 30s and 40s       the study’s lead author, Arul         which are over-expressed in        would first be used to supple-
should not ignore it       Chlnnaiyan, director of the           specific cancer subtypes.           ment a PSA blood screen.
either.”                   Michigan Center for Transla-           Researchers collected urine       Source: American Association
Source: The Herald Sun,    tional Pathology at the Uni-          samples from 234 men with          for Cancer Research website
December 17, 2007.         versity of Michigan.                  rising PSA levels before they

   The Prostate Cancer Foundation of Australia freecall hotline is 1800 22 00 99
                   or visit the website
                                                                                 Page 7
       ... prostate cancer research news update ...                                       Questions persist
                                                                                          over whether
New resources                                                                             viruses cause
                                                                                          postate cancer

to give patients                                                                          T    HE recent development of a
                                                                                               cervical cancer vaccine by
                                                                                          the 2006 Australian of the Year,
                                                                                          Professor Ian Frazer AM, has raised

more answers                                                                              the question: do viruses also cause
                                                                                          prostate cancer?
                                                                                           Initial research has shown that the
                                                                                          human papillomavirus (HPV) could

      cer Foundation of
Australia, in partnership
                              that can be downloaded
                              au under the resources
                                                           not given information on
                                                           discharge from hospital
                                                           regarding the possibility
                                                                                          play a role in the development
                                                                                          of prostate cancer. Certain
                                                                                          cancercausing HPV types are
with Impotence Austra-        heading, or a booklet        of developing urinary in-      found in close to 100 per cent of all
lia, and with an education    can be ordered through       continence after prostate      cervical cancers. Previous studies
grant from Eli Lilly, has     Impotence Australia by       surgery.                       have also found these HPV types in
produced treatED: Pros-       phoning 1800 800 614,         This new resource has         prostate cancer.
tate Edition – an updated     or phone PCFA on 1800        been developed to edu-          A joint project between the Mazda
resource on erectile dys-     220 099.                     cate men about the inci-       Foundation and the Prostate
function.                                                  dence of urinary inconti-      Cancer Foundation of Australia
 While erectile dysfunc-                                                                  has established a new research
                              A    NOTHER           new    nence following prostate
tionis an unfortunate con-                                 surgery and provides           fellowship to investigate this vital
                                   publication – Con-
sequence of prostate can-                                  practical information to       area. This Fellowship has been
                              tinence and prostate: a
cer treatment, erections                                   assist men before and af-      awarded to Dr Annika Antonsson,
                              guide for men undergoing
can be improved – and                                      ter operations, including      who is based within the Centre for
                              prostate surgery – is also
the best chance of ensur-                                  an emphasis on the im-         Immunology and Cancer Research
                              now available.
ing a future sex life is                                   portance of pelvic floor        under the supervision of Professor
with early intervention.       This resource has been      muscle exercises, diet         Frazer.
                              developed by the Con-        and lifestyle habits, infor-    “We think that undiscovered HPV
 treatED: Prostate Edi-
                              tinence Foundation of        mation about continence        types might be involved in the
tion provides simply
                              Australia in collaboration   products and where to go       development of prostate cancer
written but detailed infor-
                              with PCFA, the Urologi-      for further information.       and will use a new technique to try
mation on the impact of
                              cal Society of Australia                                    and further identify them,” says Dr
the main prostate cancer                                    The free resource is also
                              and New Zealand, the                                        Antonsson.
treatments on erections                                    recommended for health
                              Australian Physiotherapy                                     “We have been able to detect over
and how best to mitigate                                   professionals who are in
                              Association, Australian                                     150 new papillomavirus types with
this side effect.                                          contact with men requir-
                              Nurses for Continence                                       this new method and the previously
 This booklet for men and     and the Australian and       ing prostate surgery, in-
                                                           cluding urologists, urolo-     unknown HPV types will be tested
their partners follows on     New Zealand Urological
                                                           gy nurses, pre-admission       in several different ways to see if
from the original treatED     Nurses Society.
                                                           nurses, discharge plan-        they cause prostate cancer.
resource and provides
                               A recent survey found       ning coordinators and           “Identification of a virus linked
up-to-date information
                              that a year or more after    general practitioners.         to the development of prostate
on the main, proven treat-
                              prostate surgery, 66 per                                    cancer would be a very important
ments for ED.                                               Copies of both resourc-
                              cent of men experienced                                     discovery. We would then be able
 The very successful          urinary      incontinence    es are available at the        to design a test to detect these
original resource is now      which significantly af-       national website www.          HPV types, and this would make it
available in five more         fected their quality of,   from        possible to identify men at risk of
languages – Greek, Ital-      life.                        the National Continence        developing prostate cancer at an
ian, Vietnamese, Chinese                                   Helpline on 1800 33 00         early stage.
                               Significantly, 41 per        66, or the PCFA freecall
and Arabic. treatED:                                                                       “It also opens up the possibility of
                              cent of respondents also     hotline on 1800 22 00
Prostate Edition is avail-                                                                developing a vaccine against this
                              reported that they were      99.
able as a PDF document                                                                    cancer.”

      The Prostate Cancer Foundation of Australia freecall hotline is 1800 22 00 99
                      or visit the website
Page 8                       
       Research findings and news items from around the world
                                                                                                         Submitted by Trevor Hunt

How is it possible to
overcome cancer pain?
Chronic pain is a frequent complaint of oncology patients
and an important aspect of palliative care management,
though focusing on the clinical features of cancer pain can
suggest strategies to address this issue.

C    HRONIC PAIN is a well
     recognised complication
of various forms of cancer,
                                   sions or dysfunction of the pe-
                                   ripheral or central nervous sys-
                                   tems. In cancer, neuropathic
                                                                                                         However, its specific use in
                                                                                                         cancer pain settings is still
                                                                      CANCER PAIN
and it creates substantial bur-    pain is predominantly caused                                           Successful treatment of neu-
                                                                      THE effectiveness of opioids
dens for patients and carers.      by tumour infiltration or com-                                         ropathic pain in cancer patients
                                                                      in the management of intrac-
Pain may include nociceptive,      pression of the peripheral or                                         requires a multidisciplinary
                                                                      table pain such as neuropathic
neuropathic and mixed forms,       central nervous system.                                               approach. Adjuvant analge-
                                                                      pain is controversial. Adjuvant
the latter two creating signifi-     Cancer treatments includ-                                            sics should always be used in
                                                                      analgesics play an essential
cant challenges in cancer pain     ing radiotherapy, surgery and                                         combination with an appro-
                                                                      role in the management of
management.                        chemotherapeutic agents may                                           priate supportive therapeutic
                                                                      neuropathic pain. However,
  Despite its prevalence, little   also contribute to painful         antidepressants       (including   relationship and non-pharma-
data is currently available        neuropathies. In addition, de-     tricyclics) may be associated      cological treatments.
about the extent of the pain       bilitated cancer patients may      with significant side effects
suffered by cancer patients.       be prone to development of         that limit their use.              CONCLUSIONS
 A population-based study          diseases such as herpes zoster                                        CANCER pain management is
                                                                       International and Australian
was recently conducted in the      and subsequent post-herpetic                                          an ongoing challenge in pallia-
                                                                      treatment algorithms in pri-
Netherlands to obtain reliable     neuralgias.                                                           tive and primary care settings.
                                                                      mary care suggest the gabap-
information about the preva-        Patients with cancer may ex-      entinoids such as gabapentin       Neuropathic forms of pain
lence and severity of pain in      perience neuropathic pain as a     (Neurontin) and its structural     are common and frequently
cancer patients (all phases)       continuous burning, shooting       analogue pregabalin (Lyrica)       require additional adjuvant
and clinical predictors of pain.   or electric sensations (contin-    have proven evidence-based         analgesic therapies. Research
A representative sample of         uous dysesthesias), or sudden      efficacy in the treatment of        into neuropathic pain treat-
cancer patients were recruited     episodes of sharp, stabbing,       neuropathic pain and lack seri-    ments is currently ongoing;
from a cancer registry.            shooting, knife-like pain (lan-    ous adverse effects. The theory    however novel agents such
 Pain was assessed by the          cinating or paroxysmal pain).      behind their efficacy is centred    as anticonvulsant treatments
Brief Pain Inventory (BPI)          Neuropathic pain may be           on the reduction of neuronal       have recently shown promise
and adequacy of pain treat-        debilitating, distressing and      hyperexcitability.                 (particularly in the manage-
ment by the Pain Management        generally difficult to treat.                                          ment of diabetic neuropathies
                                                                       Pregabalin would appear to
Index (PMI). This study found      Neuropathic pain syndromes                                            and post-herpetic neuralgias).
                                                                      be superior to gabapentin be-
that 55 per cent of the 1429       are therefore one of the major                                        Medical professionals are
                                                                      cause of its linear pharmaco-
respondents had experienced        problems of cancer pain treat-                                        encouraged to remain up to
                                                                      kinetics, linear dose response,
pain in the past week, and 44      ment. Recognition of appropri-                                        date with emerging therapies
                                                                      faster onset of pain relief and
per cent of these patients re-     ate pain syndromes is essential                                       and ongoing research into the
                                                                      reduction in sleep disturbance
ported moderate to severe pain     for adequate management of                                            management of cancer pain.
                                                                      (within the first week of ther-
(BPI score 4).                     cancer pain. In a recent survey
                                                                      apy), as well as having an ef-
                                   of 593 cancer patients seek-                                          Source: American Society for
 Pain management treatment                                            fective starting dose of 75mg
                                   ing pain relief, 32 presented                                         Therapeutic Radiology and
was inadequate in 42 per cent                                         twice daily.
                                   with neuropathic and 181 had                                          Oncology 49th Annual Meet-
of cancer pain patients.           mixed nociceptive and neuro-        Pregabalin may therefore be       ing, October 28, 2007.
 Neuropathic pain is broadly       pathic pain syndromes.             an effective first line agent for
defined as pain caused by le-                                          managing neuropathic pain.

      The Prostate Cancer Foundation of Australia freecall hotline is 1800 22 00 99
                      or visit the website

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