For more than 60 years, the Centers for Disease Control and Prevention (CDC) has responded to a broad spectrum of natural and human-caused disasters, including food- and waterborne illnesses, disease outbreaks, chronic health challenges, terrorism incidents, hurricanes, and earthquakes. Until recently, the highly educated professionals who deploy to hot spots around the world received little training on how to deal with the potential mental and emotional effects of the stressors to which they might be exposed. Project leadership in the Office of Safety, Health and Environment (OSHE) reached out to other agencies that put their workforces into potentially dangerous environments to benchmark best practices related to protecting workforce well-being. This enabled CDC to build on the knowledge and expertise of other federal organizations. CDC's OSHE received funding for and awarded a competitively bid contract to Virtually Better Inc (VBI), a Georgia-based organization that pioneered VR in the treatment process for various psychological disorders.