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Biotage Announces New Methods for the Extraction of Key Compounds for Clinical, Environmental and Forensic Applications by staronepr


Biotage introduced a new series of application notes utilizing the industry-standard RapidTrace� SPE Workstation.

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									Biotage Announces New Methods for the Extraction of Key Compounds for
Clinical, Environmental and Forensic Applications

Charlotte, North Carolina USA, January 7, 2011 -- Biotage® (STO: BIOT), a
leading supplier of tools and technology for analytical and medicinal
chemistry, introduced a new series of application notes utilizing the
industry-standard RapidTrace® SPE Workstation. These methods are now
available at New applications include extractions from
plasma, urine and whole blood, typically assayed in clinical and forensic
protocols. Additionally, a new soil analysis method for dioxins and
furans joins the presently available EPH protocols from Biotage.

“By offering SPE methods ready for use on the RapidTrace, labs are better
able to quickly achieve consistent solid phase extraction results that
meet industry needs for low to high throughput applications” says Anna-
Karin Wihlborg, Biotage Product Manager. “These new methods further
strengthen our portfolio of support illustrate that Biotage is committed
to providing the tools our customers need to achieve greater results.”

The RapidTrace Workstation is the gold standard for efficient and
reliable solid phase extraction from low to high throughput applications.
Up to 10 RapidTrace Modules can be controlled simultaneously by one
computer allowing for a scalable solution.

RapidTrace users can receive free software updates with the new methods
pre-loaded by contacting a Biotage Representative. The RapidTrace
utilizes effortless point-and-click software allowing for simple
execution of pre-loaded methods as well as easy custom method set-up and

Newly Released Methods for RapidTrace:

-Extraction of Vitamin D from Plasma Using ISOLUTE - This method allows
extraction of the main active Vitamin D metabolites; 25-hydroxy-vitamin D
and 1a, 25-dihydroxy-vitamin D. Deficiency can result in various
disorders including osteoporosis, liver and kidney problems to increased
risk of various cancers and multiple sclerosis, making this compound
extremely clinically relevant.

-Extraction of the Cocaine Metabolite, Benzoylecgonine from Urine using
ISOLUTE HCX - Due to short half life of cocaine, the screening for the
presence of cocaine in urine is majorly accomplished via the major
metabolite of cocaine; Benzoylecgonine. It allows a profile of use to be
constructed and can be used to determine how long ago from the time of
testing the cocaine was administered.

-Extraction of Tricyclic Antidepressants from Whole Blood Using ISOLUTE
HCX Columns - Except for the use of Tricyclic antidepressants (TCAs) to
treat depressive disorders, TCA’s have been found to have significant
efficacy in the treatment of sleep disorders, ADHD, IBS and pain

-Extraction of Basic Drugs of Abuse from Biological Fluids using ISOLUTE
HCX - The typical range of drugs screened using this generic method are
Cocaine, D3 -Cocaine , Benzoylecgonine-TMS, D3-Benzoylegonine-TMS,
Amphetamine, D5-Amphetamine, Methamphetamine, Codeine, Morphine,
Amitriptyline HCL, Nortriptyline HCL, Imipramine HCL, Desipramine HCL.
These drugs represent a panel of the most significantly abused drugs as
recommended by The National Institute on Drug Abuse (NIDA).

-Extraction of Cyclosporine from Whole Blood Using ISOLUTE Columns -
Cyclosporine is an immunosuppressant used in organ transplants to
overcome rejection. Subsequent to an organ transplant, patients are
tested at regular intervals for the presence of very low levels of the

-Extraction of Environmental Contaminants Including Dioxins and Furans
from Soil and Sediment Samples Using ISOLUTE NH2 – Dioxins and furans are
a family of toxic chemicals. The levels of these chemicals in air, water
and soil are constantly monitored through screening according to EPA
guidelines, typical detection limits for these compounds in soil and
sediments are 0.1 -1.0 parts per billion.

-Extraction of the Opiates, Morphine and Codeine from urine using ISOLUTE
HCX - Morphine and codeine are two of the opiates analyzed in drugs of
abuse testing, they are both on the SAMHSA (Substance Abuse Mental Health
Service Administration) lists as drugs to be tested for workplace drug

For more information regarding the application methods and the complete
line of Biotage products for sample preparation, visit


For further press information at Biotage please contact:
Rob Thompson
Director of Marketing Communications
10430 Harris Oaks Blvd., Suite C,
Charlotte, NC USA 28269
Tel: +1 704 654 4847
Fax: +1 704 654 4917

About Biotage
Biotage offers solutions, knowledge and experience in the areas of
analytical and medicinal chemistry. The customers include the world’s top
pharma and biotech companies, as well as leading academic institutes. The
company is headquartered in Uppsala, Sweden, and has offices in the
United States, United Kingdom and Japan. Biotage has 245 employees and
had sales of SEK 394,1m in 2009. Biotage is listed on the NASDAQ OMX
Nordic Stock Exchange. Website:

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