Science at the heart of medicine Clinical Research Training at Einstein From K30 CTSA Ellie Schoenbaum MD Director CTSA Core Rese

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Science at the heart of medicine Clinical Research Training at Einstein From K30 CTSA Ellie Schoenbaum MD Director CTSA Core Rese Powered By Docstoc
					              Science at the heart of medicine




Clinical Research Training at Einstein:
           From K30 - CTSA

             Ellie Schoenbaum, MD
              Director CTSA Core
Research Education, Training & Career Development
Education and training is a cornerstone of
our CTSA

• Has historically been a strong partnership between
  Einstein and Montefiore
• Intersection between the research and educational
  missions of the medical school and medical center
• Strategic value of “ground-up” approach to building
  clinical and translational research
• Grows out of successful K30 and K12 programs
 THE CRTP (formerly K30)

• BASICS
  > Began 1998, two-year MS program with Einstein
    support
  > Didactic core –parallel mentored research project
  > Thesis is publishable paper, hypothesis driven
  > Small class ~15 Scholars form a cohort
  > Require guarantee of 50% protected time
  > MD-MS started in 2005
The CRTP Curriculum

 > Epidemiology, Biostat, Data Analysis,
   Bioethics
 > Grant Writing
 > Research Seminars
 > Library and data management skills for
   researchers
 > Electives
 > Biostatistical consultation
 > Career Development
Two Models of Training
      Dedicated                   Issues Across
                                     Schools
       Faculty



                        CTSA
                      Resources

                                      CRTP
        CRTP                             +
      Einstein                    School of Public
                                      Health




                                     MPH, PhD
     other Centers,                  Exposure
        Grants
   Medical Specialties of 112 CRTP Graduates
                   2000-2009
Emergency Med                                  11
    Family Med                        5
       Medicine                                                         41
      Neurology           2
        Ob-Gyn                            8
      Oncology        1
 Otolaryngology       1
      Pathology           2
     Pediatrics                                          25
      Pharmacy        1
     Psychiatry                   4
 Radiation Onc        1
      Radiology         2
    Rehab Med         1
        Surgery               3
                  0                       10        20        30   40        50
CRTP transformation in progress

• Mentoring groups
  > More Epidemiologists and Translational mentors

• Intensified grant writing course focuses on
  career dev K23, foundations
• Support for writing R01s
• Focus on orphan dept or small division with
  little or no clinical research
• Enrollment of Scholars in allied professions
Career development in the CTSA

• KL2 program provides an exciting template for
  these activities at Einstein
• Strong connection to our CRTP: most
  awardees have been CRTP students or
  graduates
• Links to other funding streams: K12 (e.g.,
  Child Neurology, Cancer, HIV/Drug Use,
  Nephrology), T32s, K23s, “Empire Clinical
  Research Investigator Program
PhD in Clinical Investigation:
a cultural change
 • Administratively integrated into Grad Div, which offers
   PhD in Biomedical Sciences
    > ICTR provides academic home for students
    > Courses developed to introduce clinical research
      approach
    > Epidemiology, human genetics, overview clinical
      research
 • Recruitment challenging – dismantling silos
 • Core CRTP curriculum serves as basic courses
 • Considering recruiting from med school applicants for
   MD/PhD
Definition of Translational Research*


 Translational     research    fosters  the
   multidirectional integration of basic
   research, patient-oriented research, and
   population-based research, with the
   long-term aim of improving the health of
   the public.
   __________________
   *Rubio DM, Schoenbaum EE, Lee LS et al. An Educational Framework
   for Translational Research. Acad Med. (in press)
Einstein’s Model for Translational Research
Evaluating effectiveness

• Need metrics for educational programs
• Course evaluations need more emphasis on
  competency development than student response
• Outcome metrics could be rethought in context of
  CTSA vision
   > Not just publication, but impact on health
   > Not just PI, but team science
   > Connection to community (inside, outside)
• Looking to link with CTSA national effort in conjunction
  with our internal evaluation services
Thanks to:


•   Paul Marantz, MD and Harry Shamoon, MD
•   Aileen McGinn, MS PhD
•   Ann Marie McCauley
•   Stacey Sodlosky

• And of course the Einstein CTSA

				
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