Checkpoint Formation

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Checkpoint Formation Powered By Docstoc
					 Broad GO Process


   DNA Damage



  DNA Replication


 GTPase Signaling



 Ion/AA Transport




Macroscopic Cellular
     Response
   OTHER




OTHER (cont.)
Protein/AA modifiction




   RNA Processing




      apoptosis




     biosynthetic




      chromatin



    cytoskeleton
     development




        folding




metabolism & catabolism




        mitosis
    morphogenesis




   phosphorylation




protein localization and
       transport




      proteolysis




  signal transduction




     transcription




      translation


       ubiquitin
vesicle transport
GO Process Terms
DNA damage checkpoint; DNA damage response, detection of DNA damage; DNA damage response, signal transduction; DNA damage
response, signal transduction by p53 class mediator; DNA ligation during DNA repair; DNA recombination; DNA repair; DNA synthesis during
DNA repair; UV protection; base-excision repair; cellular response to UV; double-strand break repair; double-strand break repair via
homologous recombination; double-strand break repair via nonhomologous end joining; nucleotide-excision repair, DNA damage removal;
nucleotide-excision repair, DNA gap filling; positive regulation of DNA repair; response to DNA damage stimulus; response to UV; response to
X-ray; response to gamma radiation; response to oxidative stress; response to radiation; response to reactive oxygen species; DNA damage
response, signal transduction by p53 class mediator resulting in induction of apoptosis; DNA damage response, signal transduction by p53
class mediator resulting in transcription of p21 class mediator; DNA damage response, signal transduction resulting in induction of apoptosis;
DNA Replication; DNA Replication checkpoint; DNA Replication initiation; DNA Replication, removal of RNA primer; DNA strand elongation
during DNA Replication; DNA unwinding during replication; DNA-dependent DNA Replication; mitochondrial DNA Replication; positive
regulation of DNA Replication; regulation of DNA Replication initiation; viral genome replication; negative regulation of DNA Replication;
regulation of DNA Replication; DNA replication; DNA replication initiation; DNA replication, removal of RNA primer; DNA strand elongation
activation of Rho GTPase activity; G-protein coupled receptor protein signaling pathway; Rac protein signal transduction; activation of Rac
GTPase activity; regulation of ARF GTPase activity; regulation of ARF protein signal transduction; regulation of GTPase activity; regulation of
Rab GTPase activity; regulation of Rac GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated
signal transduction; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to cGMP nucleotide
second messenger; activation of adenylate cyclase activity by G-protein signaling pathway; activation of protein kinase C activity by G-protein
ATP synthesis coupled proton transport; L-glutamate transport; anion transport; calcium ion transport; cation transport; cellular calcium ion
homeostasis; chloride transport; ion transport; membrane hyperpolarization; neutral amino acid transport; potassium ion transport; proton
transport; regulation of intracellular pH; response to zinc ion; sequestering of calcium ion; sodium ion transport; ADP transport; ATP synthesis
coupled electron transport; ATP transport; axon transport of mitochondrion; metal ion transport; negative regulation of cholesterol transport;
negative regulation of transport; organic anion transport; positive regulation of calcium ion transport into cytosol; regulation of
nucleocytoplasmic transport; sarcoplasmic reticulum calcium ion transport; zinc ion transport; calcium ion import; carbon dioxide transport; iron
T cell activation; basophil degranulation; behavioral fear response; blood coagulation; blood coagulation, extrinsic pathway; cellular defense
response; cellular response to heat; cellular response to hormone stimulus; cellular response to insulin stimulus; cellular response to nutrient
levels; cellular response to oxidative stress; complement activation, alternative pathway; complement activation, classical pathway; defense
response; eosinophil degranulation; immune response; immune system process; induction of synaptic plasticity by chemical substance;
inflammatory response; innate immune response; leukocyte activation; leukocyte chemotaxis; macrophage chemotaxis; mast cell activation;
mast cell degranulation; negative regulation of coagulation; positive chemotaxis; positive regulation of positive chemotaxis; regulation of T cell
activation; regulation of immune response; regulation of response to food; response to activity; response to amino acid stimulus; response to
antibiotic; response to axon injury; response to cadmium ion; response to calcium ion; response to carbohydrate stimulus; response to
chemical stimulus; response to corticosterone stimulus; response to cytokine stimulus; response to drug; response to electrical stimulus;
response to estradiol stimulus; response to estrogen stimulus; response to ethanol; response to heat; response to hydrogen peroxide;
response to hyperoxia; response to hypoxia; response to inorganic substance; response to insecticide; response to insulin stimulus; response
to interleukin-1; response to light stimulus; response to lipid; response to lipopolysaccharide; response to mechanical stimulus; response to
mercury ion; response to metal ion; response to nicotine; response to nutrient; response to nutrient levels; response to organic cyclic
substance; response to organic nitrogen; response to organic substance; response to peptide hormone stimulus; response to progesterone
stimulus; response to protein stimulus; response to steroid hormone stimulus; response to stimulus; response to stress; response to toxin;
B cell activation; B cell cytokine production; B cell mediated immunity; B cell proliferation; CDP-choline pathway; DNA integration; DNA
ligation; DNA mediated transformation; DNA topological change; ER overload response; Golgi localization; M phase; NAD biosynthesis via
nicotinamide riboside salvage pathway; Notch receptor processing; SMAD protein nuclear translocation; T cell activation during immune
response; T cell proliferation; T cell proliferation during immune response; V(D)J recombination; acetylcholine transport; activation-induced cell
death of T cells; actomyosin structure organization; acute-phase response; adenine salvage; adenine transport; adhesion to symbiont; adult
behavior; adult walking behavior; anagen; angiogenesis involved in wound healing; antigen processing and presentation of peptide antigen via
MHC class I; arachidonic acid secretion; aspartate transport; associative learning; attachment of GPI anchor to protein; auditory receptor cell
fate commitment; auditory receptor cell stereocilium organization; axon target recognition; base conversion or substitution editing; behavior;
beta-amyloid formation; biological_process; biotin transport; blood circulation; blood vessel endothelial cell migration; body fluid secretion;
bone resorption; calcium-dependent cell-cell adhesion; calcium-dependent cell-matrix adhesion; carbohydrate transport; cell aging; cell
chemotaxis; cell fate determination; cell fate specification; cell maturation; cell volume homeostasis; cell-cell adhesion mediated by integrin;
cell-cell signaling; cellular chloride ion homeostasis; cellular extravasation; cellular heat acclimation; cellular homeostasis; cellular process;
cellular protein localization; cellular water homeostasis; centriole replication; centriole-centriole cohesion; centrosome cycle; centrosome
organization; cerebellar cortex formation; cerebral cortex cell migration; chemotaxis; cholesterol homeostasis; cholesterol import; cholesterol
transport; choline transport; chromatin silencing at rDNA; circadian rhythm; cognition; complement activation, lectin pathway; conditioned taste
aversion; convergent extension involved in gastrulation; cytolysis; cytoplasmic transport; cytoskeletal anchoring at plasma membrane;
decidualization; deoxynucleotide transport; detection of lipopolysaccharide; detection of mechanical stimulus involved in sensory perception of
sound; detection of oxygen; detection of visible light; determination of adult lifespan; determination of left/right symmetry; digestion; dopamine
uptake; dorsal/ventral neural tube patterning; dorsal/ventral pattern formation; eating behavior; elevation of cytosolic calcium ion concentration;
elevation of endoplasmic reticulum calcium ion concentration; elevation of mitochondrial calcium ion concentration; embryonic cleavage;
endoplasmic reticulum calcium ion homeostasis; endosomal lumen acidification; endothelial cell proliferation; enzyme active site formation via
L-cysteine persulfide; epithelial cell proliferation; erythrocyte homeostasis; establishment of T cell polarity; establishment of chromatin
silencing; establishment of neuroblast polarity; establishment of planar polarity; establishment or maintenance of apical/basal cell polarity;
establishment or maintenance of cell polarity; excretion; fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty acid homeostasis; fatty
acid oxidation; female pregnancy; fertilization; fibril organization; fibrinolysis; fibroblast migration; forebrain neuroblast division; gas transport;
generation of neurons; glucose transport; glucose-6-phosphate transport; glutamate uptake during transmission of nerve impulse; grooming
behavior; heart contraction; heart looping; heme oxidation; hemolysis by symbiont of host erythrocytes; hemostasis; high-density lipoprotein
particle clearance; high-density lipoprotein particle remodeling; histamine secretion by mast cell; homeostasis of number of cells; homeostatic
process; humoral immune response; induction of an organ; initiation of viral infection; inner ear receptor stereocilium organization; inner
mitochondrial membrane organization; insulin secretion; interaction with symbiont; interleukin-2 secretion; intermediate filament cytoskeleton
organization; intermediate filament organization; interspecies interaction between organisms; intestinal absorption; intracellular transport;
isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; isotype switching to IgG isotypes; keratinization; keratinocyte activation; keratinocyte
migration; keratinocyte proliferation; killing of cells of another organism; lactation; lagging strand elongation; layer formation in the cerebral
cortex; leading strand elongation; learning; learning or memory; leucine import; leukocyte adhesion; lipopolysaccharide transport; locomotion;
macrophage activation; maintenance of DNA repeat elements; maintenance of centrosome location; maintenance of chromatin silencing;
maintenance of mitochondrion location; maintenance of organ identity; maintenance of protein location in nucleus; male meiosis; mannose
transport; mechanosensory behavior; meiotic chromosome segregation; meiotic metaphase I; melanosome transport; membrane to
membrane docking; memory; mevalonate transport; mitochondrial fission; mitochondrial fusion; mitochondrial genome maintenance;
mitochondrial membrane organization; mitochondrion organization; motor axon guidance; muscle atrophy; muscle contraction; muscle filament
sliding; muscle homeostasis; myelin maintenance in the peripheral nervous system; myeloid cell homeostasis; myo-inositol transport; myoblast
fusion; myoblast proliferation; natural killer cell mediated cytotoxicity; necrotic cell death; negative chemotaxis; negative regulation of B cell
regulation of neurotransmitter levels; regulation of organ growth; regulation of respiratory gaseous exchange; regulation of respiratory gaseous
exchange by neurological system process; regulation of resting membrane potential; regulation of smooth muscle contraction; regulation of
striated muscle contraction; regulation of survival gene product expression; regulation of synaptic transmission, GABAergic; regulation of
synaptic transmission, glutamatergic; regulation of synaptogenesis; regulation of the force of heart contraction; regulation of vasoconstriction;
regulation of viral genome replication; relaxation of vascular smooth muscle; release of cytochrome c from mitochondria; removal of
superoxide radicals; reproductive process in a multicellular organism; respiratory burst during acute inflammatory response; respiratory
electron transport chain; retina homeostasis; retinal ganglion cell axon guidance; retroviral genome replication; reverse cholesterol transport;
rhythmic process; ribosomal large subunit biogenesis; ribosomal large subunit export from nucleus; ribosomal small subunit biogenesis;
ribosomal small subunit export from nucleus; ribosome biogenesis; righting reflex; ruffle organization; sarcomere organization; sensory
perception of pain; sensory perception of smell; sensory perception of taste; sensory processing; sequestering of metal ion; single fertilization;
skeletal muscle contraction; skeletal muscle fiber adaptation; smooth endoplasmic reticulum calcium ion homeostasis; smooth muscle cell
migration; smooth muscle contraction; social behavior; somatic cell DNA recombination; somatic diversification of immunoglobulins; somatic
hypermutation of immunoglobulin genes; somatic recombination of immunoglobulin gene segments; sperm capacitation; sperm chromatin
condensation; stem cell maintenance; striated muscle contraction; substrate adhesion-dependent cell spreading; succinyl-CoA pathway;
sulfate assimilation; superoxide anion generation; surfactant homeostasis; susceptibility to T cell mediated cytotoxicity; susceptibility to natural
killer cell mediated cytotoxicity; symbiosis, encompassing mutualism through parasitism; synapsis; synaptic transmission; synaptic
transmission involved in micturition; synaptic transmission, cholinergic; synaptic transmission, dopaminergic; synaptic transmission,
glutamatergic; synaptic vesicle endocytosis; synaptic vesicle targeting; temperature homeostasis; thymic T cell selection; transcytosis;
transmission of nerve impulse; triglyceride homeostasis; triglyceride mobilization; uropod organization; vascular smooth muscle contraction;
vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure; viral envelope fusion with host membrane; virion
attachment, binding of host cell surface coreceptor; virus-host interaction; visual learning; visual perception; voluntary musculoskeletal
movement; wound healing; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; D-aspartate import; DNA mediated transformation;
DNA methylation during gametogenesis; ER overload response; adult heart development; adult walking behavior; antigen processing and
presentation of peptide antigen via MHC class I; arachidonic acid secretion; auditory behavior; axonal fasciculation; beta-amyloid formation;
bicarbonate transport; biological_process; bone remodeling; branchiomotor neuron axon guidance; cardiac muscle cell differentiation; cell
C-terminal protein amino acid methylation; N-terminal protein amino acid acetylation; histone H2A acetylation; histone H3 acetylation; histone
H3-K4 methylation; histone H4-R3 methylation; histone demethylation; histone methylation; internal protein amino acid acetylation;
methylation; negative regulation of histone acetylation; negative regulation of protein amino acid glycosylation; peptidyl-arginine N-methylation;
peptidyl-cysteine methylation; peptidyl-lysine deacetylation; positive regulation of protein sumoylation; protein amino acid C-linked
glycosylation via 2'-alpha-mannosyl-L-tryptophan; protein amino acid N-linked glycosylation; protein amino acid O-linked glycosylation; protein
amino acid demethylation; protein sumoylation; protein amino acid O-linked mannosylation; protein amino acid oxidation; protein
deneddylation; glutamate deamidation; peptidyl-amino acid modification; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;
positive regulationmRNA stabilization; CRD-mediated mRNA stabilization; RNA 3'-end processing; RNA acid ADP-ribosylation; protein amino
3'-UTR-mediated of protein modification process; post-translational protein modification; protein amino export from nucleus; RNA localization;
RNA modification; RNA transport; alternative nuclear mRNA splicing, via spliceosome; cytoplasmic mRNA Processing body assembly;
glutaminyl-tRNA aminoacylation; glutamyl-tRNA aminoacylation; glycyl-tRNA aminoacylation; histone mRNA 3'-end processing; intracellular
mRNA localization; intronless viral mRNA export from host nucleus; isoleucyl-tRNA aminoacylation; lysyl-tRNA aminoacylation; mRNA
capping; mRNA cleavage; mRNA cleavage involved in gene silencing by miRNA; mRNA export from nucleus; mRNA modification; mRNA
polyadenylation; mRNA splice site selection; mRNA stabilization; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S
rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of SSU-rRNA;
methionyl-tRNA aminoacylation; negative regulation of RNA splicing; negative regulation of nuclear mRNA splicing, via spliceosome; poly(A)+
mRNA export from nucleus; positive regulation of RNA elongation from RNA polymerase II promoter; positive regulation of mRNA 3'-end
processing; pre-microRNA Processing; primary microRNA Processing; production of miRNAs involved in gene silencing by miRNA; regulation
apoptotic chromosome condensation; apoptotic mitochondrial changes; mitochondrial fragmentation during apoptosis; neuron apoptosis;
positive regulation of neuron apoptosis; programmed cell death; recognition of apoptotic cell; regulation of anti-apoptosis; regulation of neuron
apoptosis; virus-infected cell apoptosis; negative regulation of caspase activity; DNA fragmentation involved in apoptosis; activation of caspase
activity; activation of caspase activity by cytochrome c; activation of pro-apoptotic gene products; anti-apoptosis; apoptosis; cell death; death;
germ cell programmed cell death; induction of apoptosis; induction of apoptosis by extracellular signals; induction of apoptosis by intracellular
de novo' GDP-L-fucose biosynthetic process; 'de novo' pyrimidine base biosynthetic process; 3'-phosphoadenosine 5'-phosphosulfate
biosynthetic process; 5-phosphoribose 1-diphosphate biosynthetic process; ADP biosynthetic process; CTP biosynthetic process; GDP-
mannose biosynthetic process; GPI anchor biosynthetic process; GTP biosynthetic process; L-serine biosynthetic process; Mo-molybdopterin
cofactor biosynthetic process; S-adenosylmethionine biosynthetic process; UMP biosynthetic process; UTP biosynthetic process; acetyl-CoA
biosynthetic process from pyruvate; androgen biosynthetic process; arginine biosynthetic process via ornithine; cardiolipin biosynthetic
process; carotenoid biosynthetic process; coenzyme A biosynthetic process; cysteine biosynthetic process; dTDP biosynthetic process;
diadenosine tetraphosphate biosynthetic process; extracellular polysaccharide biosynthetic process; folic acid and derivative biosynthetic
process; glycerol biosynthetic process; glycine biosynthetic process from serine; glycosaminoglycan biosynthetic process; heme biosynthetic
process; histidine biosynthetic process; hydrogen peroxide biosynthetic process; hydroxylysine biosynthetic process; hypoxanthine biosynthetic
process; inositol biosynthetic process; inositol phosphate biosynthetic process; isoprenoid biosynthetic process; macromolecule biosynthetic
process; melatonin biosynthetic process; methionine biosynthetic process; negative regulation of MHC class II biosynthetic process; negative
regulation of amyloid precursor protein biosynthetic process; negative regulation of cholesterol biosynthetic process; negative regulation of
cytokine biosynthetic process; negative regulation of glucocorticoid biosynthetic process; negative regulation of nitric oxide biosynthetic
process; negative regulation of phospholipid biosynthetic process; negative regulation of vitamin D biosynthetic process; nitric oxide
biosynthetic process; pentose biosynthetic process; phosphatidylethanolamine biosynthetic process; platelet activating factor biosynthetic
process; porphyrin biosynthetic process; positive regulation of cellular biosynthetic process; positive regulation of collagen biosynthetic
process; positive regulation of glycogen biosynthetic process; positive regulation of interferon-gamma biosynthetic process; positive regulation
of lipid biosynthetic process; positive regulation of nitric oxide biosynthetic process; positive regulation of receptor biosynthetic process; proline
biosynthetic process; purine ribonucleoside monophosphate biosynthetic process; pyridoxal phosphate biosynthetic process; pyridoxine
biosynthetic process; pyrimidine nucleotide biosynthetic process; regulation of cytokine biosynthetic process; selenocysteine biosynthetic
process; sphingomyelin biosynthetic process; tetrahydrobiopterin biosynthetic process; urate biosynthetic process; wax biosynthetic process;
DNA packaging; centromeric heterochromatin assembly; chromatin assembly or disassembly; chromatin modification; chromatin organization;
chromatin remodeling; chromatin silencing at telomere; chromosome organization; histone H3-R2 methylation; histone H4 acetylation; histone
acetylation; histone deacetylation; histone exchange; maintenance of DNA methylation; methylation-dependent chromatin silencing;
M phase specific microtubule process; actin nucleation; barbed-end actin filament capping; cytoplasmic microtubule organization;
establishment or maintenance of microtubule cytoskeleton polarity; microtubule anchoring at centrosome; microtubule depolymerization;
microtubule nucleation; microtubule organizing center organization; regulation of actin filament polymerization; regulation of actin
polymerization or depolymerization; actin crosslink formation; actin cytoskeleton organization; actin cytoskeleton reorganization; actin filament
bundle assembly; actin filament capping; actin filament organization; actin filament polymerization; actin filament severing; actin filament-
based movement; actin polymerization or depolymerization; cortical actin cytoskeleton organization; cytoskeleton organization; focal adhesion
assembly; intermediate filament bundle assembly; intermediate filament-based process; lamellipodium assembly; microtubule bundle
formation; microtubule cytoskeleton organization; microtubule-based movement; microtubule-based process; mitochondrion transport along
B cell differentiation; Cajal-Retzius cell differentiation; Leydig cell differentiation; Schwann cell development; Sertoli cell development; alpha-
beta T cell differentiation; anatomical structure development; brain morphogenesis; branching involved in ureteric bud morphogenesis;
branching morphogenesis of a tube; bronchus morphogenesis; camera-type eye morphogenesis; cardiac muscle fiber development; cardiac
muscle tissue morphogenesis; cell development; cell morphogenesis involved in differentiation; central nervous system neuron development;
central nervous system neuron differentiation; cerebellar cortex development; cerebellar cortex morphogenesis; corpus callosum development;
corpus callosum morphogenesis; dendrite morphogenesis; ectoderm development; embryonic camera-type eye development; embryonic
development ending in birth or egg hatching; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic limb
morphogenesis; embryonic neurocranium morphogenesis; endocrine pancreas development; endoderm development; endothelial cell
development; endothelial cell differentiation; enucleate erythrocyte differentiation; erythrophore differentiation; facial nerve development;
gamma-delta T cell differentiation; glial cell development; glomerular basement membrane development; hemopoietic progenitor cell
differentiation; hemopoietic stem cell differentiation; inner ear development; lateral geniculate nucleus development; lung alveolus
development; macrophage differentiation; male gonad development; maternal placenta development; mesoderm development; mitochondrion
morphogenesis; monocyte differentiation; morphogenesis of an epithelium; muscle cell differentiation; myeloid cell differentiation; myeloid
leukocyte differentiation; myeloid progenitor cell differentiation; myoblast development; negative regulation of T cell differentiation; negative
regulation of cell differentiation; negative regulation of myeloid cell differentiation; negative regulation of myeloid leukocyte differentiation;
negative regulation of myotube differentiation; neural tube development; oligodendrocyte development; optic nerve development; optic nerve
morphogenesis; organ development; osteoblast differentiation; ovarian follicle development; peripheral nervous system development; positive
regulation of alpha-beta T cell differentiation; positive regulation of astrocyte differentiation; positive regulation of cell differentiation; positive
regulation of cytotoxic T cell differentiation; positive regulation of macrophage derived foam cell differentiation; positive regulation of osteoclast
differentiation; pyramidal neuron development; regulation of T cell differentiation in the thymus; regulation of cell differentiation; regulation of
dendrite development; regulation of dendrite morphogenesis; regulation of keratinocyte differentiation; regulation of striated muscle tissue
development; respiratory tube development; retina development in camera-type eye; retinal rod cell development; skeletal muscle fiber
development; skeletal system development; skeletal system morphogenesis; skin development; smooth muscle tissue development; spinal
cord development; stem cell development; striated muscle cell development; striated muscle cell differentiation; striatum development; thyroid
gland development; tongue morphogenesis; ureteric bud development; ventricular cardiac muscle cell development; vestibulocochlear nerve
development; white fat cell differentiation; B cell lineage commitment; T cell receptor V(D)J recombination; adipose tissue development; adult
locomotory behavior; aging; angiogenesis; antral ovarian follicle growth; axon guidance; blastocyst development; blood vessel development;
de novo' posttranslational protein folding; regulation of protein folding in endoplasmic reticulum; 'de novo' protein folding; chaperone mediated
protein folding requiring cofactor; endoplasmic reticulum unfolded protein response; positive regulation of protein complex assembly; protein
complex assembly; protein destabilization; protein folding; protein heterooligomerization; protein DNA catabolic process, exonucleolytic; DNA
10-formyltetrahydrofolate catabolic process; ATP metabolic process; D-ribose catabolic process;maturation; protein maturation by protein
metabolic process; GDP-mannose metabolic process; L-lysine catabolic process; L-phenylalanine catabolic process; N-acetylglucosamine
metabolic process; acetate metabolic process; aromatic amino acid family metabolic process; beta-amyloid metabolic process; branched chain
family amino acid catabolic process; carboxylic acid metabolic process; carnitine metabolic process, CoA-linked; catecholamine metabolic
process; cellular carbohydrate metabolic process; cellular metabolic process; cellular protein metabolic process; cholesterol catabolic process;
citrate metabolic process; coenzyme A metabolic process; creatine metabolic process; cyclic nucleotide catabolic process; cysteine metabolic
process; cytosine metabolic process; dATP metabolic process; dGTP catabolic process; dUTP metabolic process; deoxyribonucleoside
catabolic process; deoxyribonucleotide catabolic process; dihydrolipoamide metabolic process; dolichol metabolic process; dopamine catabolic
process; estrogen metabolic process; folic acid metabolic process; formate metabolic process; galactitol metabolic process; galactose
metabolic process; gamma-aminobutyric acid catabolic process; gamma-aminobutyric acid metabolic process; glycerol-3-phosphate metabolic
process; glycerophospholipid metabolic process; glycoprotein catabolic process; glycosphingolipid catabolic process; glycosylceramide
catabolic process; histidine catabolic process; histone mRNA metabolic process; hydrogen peroxide metabolic process; hypoxanthine
metabolic process; inosine catabolic process; ketone body catabolic process; lactate metabolic process; leucine catabolic process; lipoate
metabolic process; long-chain fatty acid metabolic process; mRNA metabolic process; malate metabolic process; medium-chain fatty acid
catabolic process; methylglyoxal metabolic process; miRNA catabolic process; misfolded or incompletely synthesized protein catabolic
process; negative regulation of cellular protein metabolic process; negative regulation of dopamine metabolic process; negative regulation of
oxygen and reactive oxygen species metabolic process; negative regulation of proteasomal ubiquitin-dependent protein catabolic process;
neurotransmitter catabolic process; nicotinamide riboside catabolic process; nitrogen compound metabolic process; nuclear-transcribed mRNA
catabolic process; nucleotide metabolic process; oligosaccharide metabolic process; oxygen and reactive oxygen species metabolic process;
peptide catabolic process; phosphatidylinositol metabolic process; phospholipid catabolic process; phospholipid metabolic process; platelet
activating factor metabolic process; positive regulation of DNA metabolic process; positive regulation of dopamine metabolic process; positive
regulation of homocysteine metabolic process; prenylated protein catabolic process; prenylcysteine catabolic process; purine base metabolic
process; purine nucleotide metabolic process; pyrimidine deoxyribonucleotide catabolic process; pyrimidine nucleoside metabolic process;
rRNA catabolic process; regulation of dopamine metabolic process; regulation of glucocorticoid metabolic process; regulation of glycogen
catabolic process; regulation of hydrogen peroxide metabolic process; regulation of oxygen and reactive oxygen species metabolic process;
regulation of protein metabolic process; retinoic acid metabolic process; ribonucleoside diphosphate catabolic process; ribose phosphate
metabolic process; short-chain fatty acid metabolic process; snoRNA metabolic process; sphingolipid catabolic process; sphingolipid
G1 phase of mitotic cell cycle; G2 phase of mitotic cell cycle; S phase of mitotic cell cycle; attachment of spindle microtubules to kinetochore;
cell cycle process; cytokinesis after mitosis; cytokinesis during cell cycle; establishment of meiotic spindle localization; establishment of mitotic
spindle orientation; exit from mitosis; meiotic spindle organization; mitotic cell cycle; mitotic centrosome separation; mitotic metaphase; mitotic
metaphase/anaphase transition; mitotic recombination; negative regulation of cell cycle arrest; positive regulation of attachment of spindle
microtubules to kinetochore; regulation of S phase of mitotic cell cycle; regulation of cell cycle; regulation of mitosis; regulation of mitotic cell
cycle; regulation of mitotic recombination; regulation of transcription involved in G2/M-phase of mitotic cell cycle; spindle assembly; spindle
pole body organization; traversing start control point of mitotic cell cycle; cytokinesis, completion of separation; regulation of cytokinesis;
somatic stem cell division; stem cell division; G1/S transition of mitotic cell cycle; G2/M transition DNA damage checkpoint; G2/M transition of
mitotic cell cycle; attachment of spindle microtubules to kinetochore during mitosis; cell cycle; cell cycle arrest; cell cycle checkpoint; cell
anatomical structure morphogenesis; anterior/posterior pattern formation; apoptosis involved in morphogenesis; axon extension; axon
regeneration in the peripheral nervous system; axonogenesis; cell morphogenesis; embryonic skeletal system morphogenesis; embryonic
viscerocranium morphogenesis; epithelial to mesenchymal transition; face morphogenesis; hair follicle morphogenesis; heart morphogenesis;
homeostasis of number of cells within a tissue; inner ear morphogenesis; limb morphogenesis; mammary gland duct morphogenesis;
mesoderm formation; morphogenesis of embryonic epithelium; negative regulation of axon extension involved in axon guidance; negative
common-partner SMAD protein phosphorylation; lipid phosphorylation; negative regulation of tyrosine phosphorylation of Stat3 protein;
nucleoside diphosphate phosphorylation; peptidyl-histidine phosphorylation; peptidyl-tyrosine phosphorylation; positive regulation of peptidyl-
serine phosphorylation; positive regulation of phosphorylation; positive regulation of protein amino acid autophosphorylation; positive regulation
of tyrosine phosphorylation of Stat3 protein; positive regulation of tyrosine phosphorylation of Stat5 protein; regulation of dephosphorylation;
regulation of peptidyl-tyrosine phosphorylation; regulation of phosphorylation; serine phosphorylation of STAT3 protein; I-kappaB
phosphorylation; activation of MAPK activity; activation of protein kinase A activity; activation of protein kinase B activity; carbohydrate
phosphorylation; dephosphorylation; negative regulation of MAPKKK cascade; negative regulation of phosphorylation; negative regulation of
protein amino acid dephosphorylation; negative regulation of protein amino acid phosphorylation; negative regulation of protein kinase activity;
CenH3-containing nucleosome assembly at centromere; acrosome assembly; apical junction assembly; box C/D snoRNP assembly; cardiac
myofibril assembly; cellular chaperone-mediated protein complex assembly; centromeric core chromatin assembly; chaperone-mediated
protein complex assembly; cilium assembly; cis assembly of pre-catalytic spliceosome; extracellular matrix disassembly; hemidesmosome
assembly; mature ribosome assembly; microspike assembly; mitochondrial outer membrane translocase complex assembly; mitochondrial
respiratory chain complex III assembly; mitochondrial respiratory chain complex IV assembly; mitochondrial respiratory chain complex
assembly; myofibril assembly; negative regulation of inclusion body assembly; negative regulation of protein export from nucleus; nuclear
envelope disassembly; nuclear pore complex assembly; peptide antigen assembly with MHC class I protein complex; positive regulation of
cellular chaperone-mediated protein complex assembly; positive regulation of flagellum assembly; positive regulation of protein complex
disassembly; positive regulation of protein import into nucleus; positive regulation of pseudopodium assembly; protein import into mitochondrial
inner membrane; protein import into mitochondrial matrix; regulation of protein complex assembly; regulation of protein import into nucleus,
translocation; ribosomal large subunit assembly; ribosomal protein import into nucleus; ribosomal small subunit assembly; ribosome assembly;
sensory cilium assembly; skeletal muscle thick filament assembly; skeletal muscle thin filament assembly; snRNP protein import into nucleus;
spliceosome assembly; stress fiber assembly; stress granule assembly; tight junction assembly; cytoplasmic sequestering of NF-kappaB;
nuclear import; nuclear translocation of MAPK; protein heterotetramerization; protein homotrimerization; protein localization in organelle;
membrane protein ectodomain proteolysis; membrane protein intracellular domain proteolysis; regulation of protein stability; regulation of
proteolysis; ER-associated protein catabolic process; cyclin catabolic process; modification-dependent protein catabolic process; positive
regulation of proteolysis; protein autoprocessing; protein catabolic process; proteolysis; proteolysis involved in cellular protein catabolic
process; receptor catabolic process;
B cell receptor signaling pathway; BMP signaling pathway; ER-nuclear signaling pathway; JAK-STAT cascade; Notch signaling pathway; T cell
receptor signaling pathway; cytokine-mediated signaling pathway; ephrin receptor signaling pathway; epidermal growth factor receptor
signaling pathway; estrogen receptor signaling pathway; fibroblast growth factor receptor signaling pathway; gamma-aminobutyric acid
signaling pathway; insulin-like growth factor receptor signaling pathway; negative regulation of Ras protein signal transduction; negative
regulation of epidermal growth factor receptor signaling pathway; negative regulation of estrogen receptor signaling pathway; negative
regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of signal transduction; negative regulation of smoothened
signaling pathway involved in ventral spinal cord patterning; platelet-derived growth factor receptor signaling pathway; positive regulation of
ERK1 and ERK2 cascade; positive regulation of Rac protein signal transduction; positive regulation of Wnt receptor signaling pathway; positive
regulation of epidermal growth factor receptor signaling pathway; positive regulation of protein kinase A signaling cascade; regulation of Wnt
receptor signaling pathway; regulation of androgen receptor signaling pathway; regulation of signal transduction; regulation of smoothened
signaling pathway; regulation of stress-activated MAPK cascade; smoothened signaling pathway; smoothened signaling pathway involved in
regulation of granule cell precursor cell proliferation; smoothened signaling pathway involved in ventral spinal cord patterning; steroid hormone
receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; two-component signal transduction system (phosphorelay);
activation of MAPKK activity; inactivation of MAPK activity; negative regulation of MAP kinase activity; second-messenger-mediated signaling;
ARF protein signal transduction; I-kappaB kinase/NF-kappaB cascade; JNK cascade; MAPKKK cascade; MyD88-dependent toll-like receptor
signaling pathway; Ras protein signal transduction; Rho protein signal transduction; SMAD protein complex assembly; TOR signaling pathway;
Wnt receptor signaling pathway; activation of JUN kinase activity; activation of NF-kappaB-inducing kinase activity; activation of phospholipase
D activity; androgen receptor signaling pathway; calcium ion-dependent exocytosis; calcium-mediated signaling; cell communication; cell
surface receptor linked signaling pathway; glucocorticoid receptor signaling pathway; hormone-mediated signaling pathway; inhibition of
adenylate cyclase activity by dopamine receptor signaling pathway; insulin receptor signaling pathway; integrin-mediated signaling pathway;
RNA polymerase II transcriptional preinitiation complex assembly; chromatin-mediated maintenance of transcription; negative regulation by
host of viral transcription; positive regulation of transcription factor activity; positive regulation of transcription initiation from RNA polymerase II
promoter; positive regulation of transcription of Notch receptor target; rRNA transcription; regulation of transcription from RNA polymerase I
promoter; regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor; transcription from RNA polymerase I
promoter; transcription initiation from RNA polymerase III promoter; transcription termination; 5S class rRNA transcription; RNA elongation
from RNA polymerase II promoter; negative regulation of gene-specific transcription from RNA polymerase II promoter; negative regulation of
transcription; negative regulation of transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; negative
regulation of transcription, DNA-dependent; positive regulation of NF-kappaB transcription factor activity; positive regulation of RNA
polymerase II transcriptional preinitiation complex assembly; positive regulation of gene-specific transcription; positive regulation of gene-
specific transcription from RNA polymerase II promoter; positive regulation of transcription; positive regulation of to membrane, signal
SRP-dependent cotranslational protein targeting to membrane; SRP-dependent cotranslational protein targeting transcription from RNA
sequence recognition; SRP-dependent cotranslational protein targeting to membrane, translocation; negative regulation of translation involved
in gene silencing by miRNA; negative regulation of translational elongation; negative regulation of translational initiation; positive regulation of
translational elongation; positive regulation of translational termination; regulation of translational fidelity; regulation of translational termination;
translational frameshifting; alanyl-tRNA aminoacylation; arginyl-tRNA aminoacylation; asparaginyl-tRNA aminoacylation; aspartyl-tRNA
histone H2B ubiquitination; histone monoubiquitination; histone ubiquitination; protein K11-linked ubiquitination; protein K63-linked
deubiquitination; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; negative regulation of
protein ubiquitination; negative regulation of ubiquitin-protein ligase activity; negative regulation of ubiquitin-protein ligase activity during mitotic
cell cycle; positive regulation of ligase activity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive
regulation of protein ubiquitination; positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-
Golgi to plasma membrane CFTR protein transport; Golgi to plasma membrane protein transport; Golgi to plasma membrane transport;
phagocytosis; receptor recycling; regulation of endocytosis; regulation of phagocytosis; COPI coating of Golgi vesicle; ER to Golgi vesicle-
mediated transport; Golgi organization; Golgi to endosome transport; Golgi vesicle transport; autophagic vacuole assembly; autophagy;
cellular membrane fusion; cellular membrane organization; chaperone-mediated autophagy; early endosome to late endosome transport;
endocytosis; endosome organization; endosome to lysosome transport; endosome to lysosome transport via multivesicular body sorting
pathway; endosome transport; endosome transport via multivesicular body sorting pathway; exocytosis; fatty acid transport; glutamate
secretion; intra-Golgi vesicle-mediated transport; lipid transport; lysosome organization; negative regulation of macroautophagy; phagocytosis,
engulfment; plasma membrane to endosome transport; positive regulation of macroautophagy; positive regulation of phagocytosis; positive
 Gene Symbol    GO Process
   ABHD10       no annotation
   ANKFY1       no annotation
    ANP32E      no annotation
    BRWD2       no annotation
    BSDC1       no annotation
    BTBD8       no annotation
   C13orf18     no annotation
  C14orf103     no annotation
   C14orf80     no annotation
   C17orf42     no annotation
    C18orf8     no annotation
   C7orf28A     no annotation
     CEP78      no annotation
    CKAP4       no annotation
DKFZP434B0335   no annotation
   DYX1C1       No annotation
    EFHA1       no annotation
   EMILIN3      no annotation
   FAM62B       no annotation
     FLCN       no annotation
   FLJ12716     no annotation
     FLNC       no annotation
     FNIP1      no annotation
     FXR2       no annotation
    FYCO1
 GABARAPL1      no annotation
     GBAS       no annotation
     GLG1       no annotation
  HNRPA3P1      no annotation
   KIAA0226     no annotation
   KIAA0265     no annotation
   KIAA0284     no annotation
   KIAA0329     no annotation
   KIAA0404     no annotation
   KIAA0831     no annotation
   LDOC1L       no annotation
    LGALS7      no annotation
   MAGED2       no annotation
    MAP1A       no annotation
    MON1B       no annotation
   MRPL38       no annotation
    MUTED       no annotation
     NBR1       no annotation
  NIPSNAP1      no annotation
    NSUN4       no annotation
   NUDCD3       no annotation
   RAD54L2      no annotation
     RCN2       no annotation
SH3GLB2   no annotation
 SMCR8    no annotation
 TELO2    no annotation
TMEM160   no annotation
 TRABD    no annotation
 TTC15    no annotation
  WAC     no annotation
 WDR45    no annotation
 WDR62    no annotation
                                       Comments
                      GO function/component mitochondrial, peptidase
                          GO component endosomal membrane
                    GO component cytoplasmic membrane bounded vesicle
                                         ubiquitin

                                           ubiquitin
                                         no annotation
                                            ATG2B

                                     endonuclease domain


                                GO component cytoskeleton
                             SMC_prok_B, links er to microtubules
                                         TECPR1

                                   GO function calcium binding
                                          SMC_prok_B
                  C2 domain, ESYT2 extended synaptotagmin-like protein 2
                                    GO component cytoplasm
                                           Foie-gras_1
                       GO function/component actin binding cytoskeleton
        energy and/or nutrient sensing through the AMPK and mTOR signaling pathways
                                  contains RNA binding domain
                                      Binds Rab7 and PI3P
                               GO component autophagic vacuole
                 vesicle trafficking based on presence of a NIPSNAP domain
                                       golgi glycoprotein 1
                                          pseudogene
                                             Rubicon


                                         TECPR2
                                          ATG2A
                                     ATG14, SMC_prok_B

                                            galectin

                          microtubule binding GO component term
Mon1 and Ccz1 functions with the small GTPase Ypt7 to mediate vesicle trafficking to the vacuole
                                 mitochondrial GO component
        component of BLOC-1 (biogenesis of lysosome-related organelles complex 1)
                                   autophagy cargo receptor
                        vesicle transport based on NIPSNAP domain
                                       methyl transferase
                      localizes to the Golgi apparatus during interphase
                             helicase, nuclearGO component term
                               ER localized GO component term
          vesicle transport

              DNA repair
  predicted transmembrane protein
               ubiquitin
                 TPR
    nuclear GO component term
phosphoinositide binding WD40 protein

				
DOCUMENT INFO
Description: Checkpoint Formation document sample