411-10 jd by ashrafp

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									                                    Academic Neurosurgery Unit
                                     Clinical Neuroscience Centre
                              Division of Cardiac and Vascular Sciences

                                           JOB DESCRIPTION

                 McKissock and UKSCIRN Research Fellow in Neurosurgery
                                   (Ref. No: 411-10)


Sir Wylie McKissock founded the St George’s Hospital Neurosurgical Unit at Atkinson
Morley’s Hospital during the Second World War and under his guidance it grew to be the
largest neurosurgical unit in London. Sir Wylie appreciated that lessons could be learned
from this large volume of clinical material that would be of benefit to the advancement of
neurosurgery. Some of his landmark publications are still cited in the current neurosurgical

In 2003 the Neurosurgical Unit moved to the purpose-built Atkinson Morley Regional
Neuroscience centre on the South West London campus of the Medical School at St
George’s University of London (SGUL) and the large and busy St George’s Healthcare Trust
(SGHT). The Atkinson Morley Regional Neuroscience centre serves a population of 3
million in South West London, Surrey, and parts of Kent, Sussex, Hampshire, Middlesex,
and Berkshire. The Neurosurgical Unit is staffed by 7 neurosurgeons, supported by 18
neurologists, 5 neuroradiologists, 2 neurophysiologists, neuropathology, neuroanaesthesia
and neuropsychology underpinned by state-of-the-art clinical imaging and other
investigational facilities. The combination of a large patient population and excellent
infrastructure offers outstanding facilities for Clinical Neuroscience research.

In 1990 SGUL made a major commitment to Neurosurgical research with the appointment of
a clinical senior lecturer in Neurosurgery followed by a Foundation Chair (Professor B A Bell)
and two lecturers in Neurosurgery. In 2000 SGUL strengthened Clinical Neuroscience
research with the appointment of a Foundation Professor of Neurology (H S Markus), two
non-clinical senior lecturer/lecturer posts, and a clinical senior lecturer in Neurology (Dr H
Cock). In 2006 it has been further strengthened by the recruitment of a new Reader in
Neurosurgery (Mr M C Papadopoulos). This investment has proved extremely successful
with an expansion in academic Clinical Neuroscience staff numbers to >30, and current
research grant income of >£4M from external peer-reviewed sources including
programme/project grants from the Wellcome Trust, EPSRC, BBSRC, BHF, Stroke
Association, CRUK, Research into Ageing, European Union, a Wellcome Clinical Science
Fellowship, and PhD studentships from MRC and Research into Ageing.

One major theme underpinning this research and grant income is MRI. SGUL has a
longstanding record of major achievements in MR research particularly in MRS, led by
Professor John Griffiths and now following his planned departure by Dr Franklyn Howe. We
have dedicated research time on a 1.5T MR scanner, which is currently being updated to a
3T MR scanner. The Medical School invested £400,000 of SRIF money in 2000 to upgrade

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the 1.5T scanner to enable echo-planar imaging. This has facilitated an internationally
competitive research programme in brain tumours.


The McKissock Research Fellow that is endowed by the Neurosciences Research
Foundation is a whole time research appointment. The research will include elements of
laboratory and clinical research and will largely be conducted within SGUL. The post is also
supported by the UK Spinal Cord Injuries Research Network (UKSCIRN).


The McKissock Research Fellow will be expected to pursue a number of research projects
under the direction of Mr M C Papadopoulos and Professor B A Bell at SGUL, and to ensure
that they organise their time in such a way that research is concluded within the time-scale
of the funding to enable their findings to be published.

The candidate is expected to work in the field of spinal cord injury. The idea behind the study
arose from our recent work on the deleterious role of spinal cord oedema following a spinal
cord injury (see Saadoun et al. Brain 2008;131:1087-98). The aim of this study is to develop
a novel technique to measure spinal cord pressure following a spinal cord injury in patients.
This is analogous to the monitoring of intracranial pressure following a brain injury. The
study will determine if the pressure becomes elevated following spinal cord injury and
whether dugs used to reduce elevated intracranial pressure also reduce elevated spinal cord
pressure. The study will take place at St. George’s Hospital (Atkinson Morley Wing), National
Hospital for Neurology and Neurosurgery (Queen Square), Royal National Orthopaedic
Hospital (Stanmore) and King’s College Hospital. The Fellow is expected to help recruit
patients into the study within 48 hours of injury, insert the pressure monitor, collect and
analyse data and troubleshoot, and discuss the progress of the study with the co-ordinating
committee on a regular basis. The fellow will have access to a rodent microsurgery
laboratory and general laboratory facilities if required.

They will also be expected to prepare a thesis based on this research for submission at the
end of the Fellowship to their University for the degree of MD.

The McKissock Research Fellow will help to co-ordinate the monthly Clinical Neuroscience
research meetings that are held and will both present findings from their own on-going
research and explore areas for cross-collaboration with other members of the Centre for
Clinical Neuroscience in SGUL who will be presenting their findings at that meeting. The
Research Fellow will also meet weekly with the Reader and Professor of Neurosurgery to
account for their progress during the previous week, to take advice, and to explore new
avenues of research where work so far has failed to bear fruit.

Other duties include a regular teaching commitment to the medical students that are
attached to the Neurosurgical Unit for their clinical neuroscience teaching. The candidate
will also participate in the lecture programme to the Undergraduate and Graduate Entry
Programme medical students and will be required to assist with organisation and teaching of
Special Study Modules on neurosurgical subjects.

The McKissock Research Fellow will participate in the neurosurgical specialist registrar on-
call rota for evening and weekend cover and will be paid separately by St George’s NHS
Trust for these on-call duties which will be shared with the other two Research Fellows in
Neurosurgery and the seven NHS neurosurgical specialist registrars


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The successful candidate will have use of the following facilities at SGUL, at St. George’s
and other participating Hospitals:
    Patients, Neuro-ICU, Operating theatres
    Pressure probes and monitoring and data analysis equipment
    A rodent microsurgery laboratory
    A general laboratory including cell culture facilities
    Computing facilities
    Dedicated research time on a GE Signa 1.5T MR scanner (or the new 3T MR
       scanner) with echo-planar imaging and the support of a MR spectroscopist, MR
       physicist and an image analyst with particular expertise in diffusion tensor MRI
    Other common facilities within the medical school such as electron microscopy

This project requires a collaboration with the National Hospital for Neurology and
Neurosurgery (Mr David Choi), the Royal National Orthopaedic Hospital (Mr Kia Rezajooi),
King’s College Hospital (Mr. Nick Thomas) as well as the department of anaesthesia at St.
George’s Hospital (Dr. Argyro Zoumprouli) and the department of neurology/neurophysiology
at St. George’s Hospital (Dr. Maria Georgala). Collaboration with other Divisions in SGUL is
encouraged and Neurosurgery has forged links with the Division of Basic Medical Sciences.
The candidate will also have access to the extensive library and media production facilities
at SGUL.


The Academic Neurosurgery Unit moved from laboratories at Atkinson Morley’s Hospital to
refurbished new office space with a microsurgical laboratory at SGUL in 2003 and in 2005
an additional large laboratory was made available for Mr Papadopoulos’ research
programme. The Unit has been very successful in obtaining external funding and has major
grants supporting the study of brain aquaporins, proton magnetic resonance spectroscopy
and diffusion tensor imaging of brain tumours and Xe CT measurement of regional cerebral
blood flow.

The Academic Neurosurgery Unit is part of the Clinical Neuroscience Centre within the
SGUL Division of Cardiovascular Sciences and the Centre includes the Academic Neurology
Stroke and Epilepsy Units. The Academic Neurosurgery Unit is closely associated with the
Atkinson Morley Neuroscience centre which is part of St. George’s Hospital and the
academic clinical staff have honorary NHS contracts. The Atkinson Morley Neuroscience
centre offers in-patient and outpatient neurosurgery, neurology, and neurorehabilitation
services supported by on site diagnostic services to the district general hospitals in SW
Thames Region.

Academic Neurosurgery Unit Staff
Professor B Anthony Bell Professor of Neurosurgery
Mr Marios C Papadopoulos Reader in Neurosurgery
Mr Timothy Jones         Rupert Johnson Lecturer in Neurosurgery
Mr Matthew Crocker       McKissock Research Fellow in Neurosurgery
Dr Samira Saadoun        Post Doctoral Research Fellow
Mrs Minal Patel          Academic PA
Miss Samantha Rutledge   Clinical PA
Research technician      To be appointed

Academic Neurology Unit Staff
Professor Hugh S Markus  Professor of Neurology
Dr Hannah Cock           Senior Lecturer in Neurology
Dr Franklyn Howe         Non-clinical Reader in Neuroimaging
Dr Steve Bevan           Non-clinical Senior Lecturer in Genetics
Dr Rebecca Charlton      Research Neuropsychologist

                                                   Page 3 of 16
Dr Usman Khan                       Clinical Research Fellow
Dr Andrew Mackinnon                 Clinical Research Fellow
Dr Arani Nitkunan                   Clinical Research Fellow
Dr Martin Punter                    Clinical Research Fellow
Dr Robyn Labrum                     Research Associate
Dr Sonia Abilleira-Castells         Research Associate
Kelly Gormley                       Research Associate
Jill Brown                          Research Associate
Dr Yuji Shen                        Physicist/Image Processing Research Fellow
Abhinandan Deb                      Computer Programmer/ Research Associate
Sheila Reihill                      Research Associate
Linda Porteous                      Stroke Register Co-ordinator
Kate Martin                         PA/Departmental Secretary

Current Research in the Clinical Neuroscience Centre

Current work within the Clinical Neuroscience Centre is funded from a variety of grant giving
bodies including Programme Grant support from the MRC, Wellcome Trust, Guthy Jackson
foundation, UK Spinal Cord Injury Research Network (UKSCIRN), European Union, CRUK,
Stroke Association, British Heart Foundation, Neurosciences Research Foundation, and
Research into Ageing, and Project Grant support from Stroke Association, PPP Healthcare,
British Heart Foundation, NHS Research & Development, St George’s Charitable
Foundation, and EPSRC.

Mr Marios Papadopoulos and Dr. Samira Saadoun have a dedicated laboratory pursuing
research into aquaporin water channels. These channels control water flux within CNS
tissues and play important roles in the formation and elimination of brain and spinal cord
oedema as well as in the pathogenesis of the demyelinating condition ‘neuromyelitis optica’.

Diffusion-weighted Magnetic Resonance
Mr Timothy Jones is pursuing collaborative research with Dr Tom Barrick using diffusion MR
anisotropic mapping of white matter tracts in the brain around mass lesions that include
intrinsic brain tumours. The applications include delineating the brain-tumour boundary
using advanced imaging techniques.

Mr. Matthew Crocker is pursuing a research project in collaboration with the Institute of
Cancer. He is using antibody microarrays to identify brain tumour markers in patient serum.
He is defining the serum angiogenic profile of patients with glioblastoma multiforme and will
use this to identify subgroups of glioblastoma that have distinct angiogenic profiles and
different prognosis.

Magnetic Resonance Spectroscopy
Dr Franklyn Howe leads a programme applying MRS to the diagnosis of intracerebral
tumours in collaboration with Professors Bell and Griffiths and contributed to the
INTERPRET database of proton MRS characteristics of intracerebral tumours funded by a
EU grant. This work has led on to the E-TUMOUR project funded a programme grant from
the European Union. SGUL is a key partner in this international study involving centres is
Spain, France, Holland and across the UK.

Genetics of ischaemic stroke
Genetic studies are looking at genetic risk factors for sporadic ischaemic stroke. We have a
large (>1000) database of carefully phenotyped cases of stroke and are carrying out a
national surveillance project to establish the prevalence and optimal screening protocols for
the autosomal dominant form of sub cortical stroke, CADASIL. We are looking at the

                                                   Page 4 of 16
genetics of an intermediate phenotype for stroke, carotid intima-media thickness measured
using high-resolution ultrasound. This is a large prospective community study of almost
5,000 individuals (the Carotid Atherosclerosis Progression Study). We are particularly
interested in the role of cytokine genes and gene-environment interactions. Additional
projects include the genetics of cerebral small vessel disease and the role of variation in
genes affecting endothelial function, and the genetics of stroke in UK African Caribbeans.

Ultrasonic imaging in stroke
There is a programme looking at both technical developments and the clinical application of
Doppler ultrasound to detect asymptomatic circulating emboli. This work ranges from signal
processing to improve the detection of emboli, to a large international multi-centre study to
look at their predictive value. A particular interest is the use of this technique to evaluate
novel anti-platelet approaches. In this area we are evaluating the novel nitric oxide donor, S-
nitrosothiol as an anti-platelet agent, and Professor Markus co-Chairs the CARESS study
using this technique to look at the effect of Clopidogrel in addition to aspirin in patients with
carotid artery stenosis.

Magnetic resonance imaging in stroke
There is a programme applying novel magnetic resonance imaging techniques to investigate
the pathogenesis of cerebrovascular disease, particularly sub cortical vascular disease. This
is in close collaboration with Professor Steve Williams at the Institute of Psychiatry and the
work has recently been extended to look at the mechanisms involved in cognitive decline
with normal ageing with a Programme Grant from Research into Ageing. There is a strong
interest in magnetic resonance spectroscopy within the School with a research group
headed by Professor John Griffiths and Dr Franklyn Howe and previous studies have applied
this MR modality to acute stroke.

Dr Hannah Cock has recently arrived and has transferred her group, which has a particular
interest in looking at mechanisms of epileptiform seizures in animal models.

Multiple Sclerosis
Dr David Barnes runs a programme of clinical research in Multiple Sclerosis including
participation in planning and recruitment to recent and current beta-interferon and co-
polymer trials.

Movement Disorders
Dr Oliver Foster runs a programme of research in Parkinson’s disease including direction of
the UK PDRG brain bank at Queens Square and clinical trials of new therapeutic agents.


The St George’s Neurosurgical Unit was established during the Second World War originally
at Atkinson Morley’s Hospital in Wimbledon. In 1971 the prototype EMI scanner was
commissioned there for its first clinical trial and created the revolution in computed
tomographic imaging that has followed.

An academic Neuroscience Department was initiated in 1986 with the appointment of a
Senior Lecturer in Neurology, and in 1991 with the appointment of a Professor of

The unit transferred to the St. George’s Hospital Tooting site in October 2003 and houses a
total of 54 beds, comprising 36 adult male and female beds, 12 acute stroke beds, 2
paediatric neuro beds and 4 private neurosurgery beds. There are 8 beds in a dedicated
neuro intensive care unit. In addition to these beds there are 8 dedicated paediatric
neuroscience beds within the Paediatric Unit located in Lanesborough Wing. The catchment

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area comprises a population of approximately 3 million and annual admissions totalling
around 2,500 neurosurgical patients.

There are three operating theatres for sole neurosurgical use. A stealth neuronavigation
system as well as CRW frame based stereotaxy systems are available. Each theatre has an
operating microscope and there are two ultrasonic aspirators available. Operations total
approximately 2000 procedures annually.

The Neuroradiology Department contains one 16-slice spinal CT scanner with facilities for
CT angiography and Xenon regional cerebral blood flow measurement and a state of the art
Phillips 1.5 Tesla MR system equipped with high gradients. There are two rooms for digital
subtraction angiography; one with biplane angiography equipment and the other with a
single plane with flat plate technology. A Doppler ultrasound is also available. All imaging in
the department is on a PACS based system (Picture Archive and Communication System).
There are currently two Consultant Interventional Neuroradiologists with an active
programme of endovascular procedures on two whole days per week as well as providing an
emergency service.

The Out Patient Department provides extensive facilities for the whole of the Neuroscience
Service Centre.

One Consultant Neuropathologist provides a full neuropathology service including immediate
per-operative smears.

There is a fully equipped Neurophysiology Department with two consultants and supporting
technical staff.

Paediatric support is provided by a Paediatric SpR attached to the Neurology and
Neurosurgery Departments and General Paediatric Surgery SpR’s and SHO’s. Paediatric
medical advice is available from the on-call Consultant Paediatrician.

Neurosurgical Staffing

The Department of Neurosurgery has seven consultants:
      Prof B A Bell MD FRCS
      Mr M C Papadopoulos MA MD FRCS(SN) – Reader
      Mr H T Marsh MA FRCS
      Mr F G Johnston MA FRCS
      Mr S R Stapleton MD FRCS(SN) – SDU Leader
      Mr A J Martin BSc FRCS(SN)
      Mr P S Minhas MA BMedSci FRCS(SN)

There are seven SpR’s, five of whom rotate through the neurosurgical units of Hurstwood
Park, the National Hospital for Neurology and Neurosurgery and The Hospital for Sick
Children, Great Ormond Street as organised by the Specialty Training Committee for South
Thames. Two of whom are trainees from the Department of Neurosurgery, University of
Washington, Seattle, USA.       There are also a four Lecturers within the Academic
Neurosurgical Unit at St. George’s Medical School.

There are currently 5 SHO’s and one clinical fellow, one of whom is on rotation from
Kingston Hospital.

The department undertakes daily undergraduate and postgraduate teaching. There is a
daily meeting of the neurosurgical team as well as weekly multidisciplinary meetings with the
Neuro Oncologists from the Royal Marsden Hospital and monthly combined pituitary and
paediatric neuro-oncology meetings.

                                                   Page 6 of 16
Associated Departments

The Clinical Neuroscience Unit has a full range of neuroscience disciplines:

Consultant Neurologists:
       Dr. A. Al-Memar              Dr. G. Kimber                 Dr S G Wilson        Dr. P. Hart
       Dr. D. Barnes                Dr. R O McKeran               Dr. D. Wren          Dr. J. Mǖller
       Dr. S. Omer                  Dr. A. Fowle                  Dr. O. Foster (SDU Leader)
       Dr. B. MacDonald             Dr. F E G Schőn               Dr. M-H Marion       Dr. J. Kimber
       Dr. G. Warner                Dr T Von Oertzen              Prof H S Markus      Dr. H. Cock

Consultant Neuroradiologists:
       Dr. J A Britton (SDU Leader)                               Dr. P. Rich
       Dr. A G Clifton (Service Centre Chair)                     Dr. D. Johnson

Consultant Neurophysiologists:
       Dr. M S Schwartz
       Dr. H. Modarres
       Dr. M. Georgala

Consultant Neuropathologist:
       Dr. L. Bridges

Consultant Neuroanaesthetists:
       Dr. J. Dinsmore      Dr. B. Sutton (SDU Leader)
       Dr. M. Kraayenbrink Dr. P. Razis
       Dr. R. Ruggier       Dr. A. Zoumprouli
       Dr. K. Jones         Dr. N. Burgess
       Dr. A. Gardner

There is a Consultant Neuroanaesthetist on the Intensive Care Unit daily.

Pain Management
      Dr. J. Blackburn
      Dr. A. Nicolaou

Neurorehabilitation facilities are available in the Wolfson Neurorehabilitation Centre, with
specialist physiotherapy, neuropsychologists, occupational therapy and speech & language

One of the Maxillo-Facial Surgeons at the Royal Marsden Hospital has an Honorary
Consultant appointment in the Unit and undertakes skull base surgery in joint procedures.
A neuro-ophthalmology service is offered once a week by one of the Ophthalmic Surgeons.

Background to St George's, University of London

St George’s, University of London together with St George’s Hospital, is housed in modern
buildings in Tooting, in south London. It is a research-based School of Medicine, Biomedical
Sciences, Health and Social Care Sciences. The School is closely integrated with extensive
secondary and tertiary clinical NHS provision. There are currently some 140 postgraduates
working for research degrees (e.g. PhD, MD) and over 850 students registered on the five-
year MB BS (Bachelor of Medicine, Bachelor of Surgery) course leading to qualification in
medicine, and 40-50 students on intercalated BSc courses. Other courses include a 3-4 year
BSc Biomedical Sciences and, in the School's Faculty of Healthcare Sciences (joint with
Kingston University), undergraduate and diploma students in Physiotherapy, Radiography,
Nursing and Midwifery and Social Work. There are multi-professional taught postgraduate

                                                   Page 7 of 16
courses in a range of subjects. The School was granted approval to introduce in 2000 an
innovative 4-year accelerated programme for graduate entrants from any discipline as an
addition to the existing 5 year course in Medicine.
Research interests on the combined Medical School and Hospital site are wide-ranging and
increasingly strong, encompassing a spectrum from basic science investigations to applied
clinical and health services research. It is the School’s explicit intention to link strategically
basic and clinical research in order to capitalise on their co-location on a single site. The
School has a strong tradition of giving younger investigators the intellectual space to develop
their careers. Positive interdisciplinary and interdepartmental interactions are the norm.

There are a total of about 150 researchers on site with close links at the clinical level to
research and patient bases in General Practices around the south-west of London. In
addition, Pathfinder NHS Trust provides a large psychiatric patient base at the near-by
Springfield Hospital. There are also good links with the St. Helier Hospital which, like St.
George’s Hospital, is a large general hospital as well as with a number of other hospitals in
the South London area.

About a third of the staff on site are researching in the basic science area although some of
these investigations are carried out in surgery, paediatrics, microbiology and pathology. The
large majority of basic science research staff have research assistants and/or PhD students
and are in receipt of external funding from Research Councils and Charities. As a group
these were rated 4 in the last Research Assessment Exercise. A group of similar size is
active in clinical research in a variety of areas. This group includes Infectious Diseases and
Cardiological Sciences, both of which were flagged as being of special excellence in the last
Research Assessment Exercise. About 40 staff in Community Medicine are research active;
the latter includes Epidemiology which was flagged as being of special excellence in the last
Research Assessment Exercise. Recently new appointments have been initiated in this
area with the aim of strengthening research teams working in public health, primary care,
and health services research. In addition to some 150 permanent positions for active
researchers, there are about 200 research assistants and 140 PhD and MD students (both
full and part-time).

Funding for research comes mainly from external sources which are of course very varied
but including Research Councils, major charities, a wide spectrum of specialist charities,
pharmaceutical and other industrial sponsors. Total research income was about £16M last
year and is on a rapidly rising trend. Competitive bids are entertained for funding of
equipment, repairs, maintenance contracts or other, often multi-user, facilities by the
Equipment Committee which is a sub-committee of the Research & Development
Committee. Research on the site is nurtured by several recently formed theme groups
which organise open days with poster presentations and invited lectures. These meet at
intervals and are run by elected organising committees. Their aim is to co-ordinate research
in their area of interest and to draw together all those on site with a common interest in the
theme and to encourage collaborations and organise joint grant applications. So far theme
groups in Cardiovascular Disease, Cancer, Intracellular Pathogens and Molecular Medicine
have been established.

Background to St. George’s Healthcare NHS Trust

St. George’s Healthcare NHS Trust is one of the largest health care units in the United
Kingdom, accommodating around 1000 beds and treating around 86,000 inpatient and day
cases, 340,000 outpatients and performing 23,000 operative procedures annually. The
Trust employs almost 5000 staff incorporating 697 Medical and Dental Staff. It provides
general acute services together with specialty tertiary services including neurosciences,
cardiothoracic, and specialist children’s services.

                                                   Page 8 of 16
St. George’s Hospital is the main teaching hospital in the western sector of the South
Thames, and as such has developed links with most district general hospitals throughout
South Thames (West) and supports a significant training programme for junior doctors who
rotate through the Trust.

The Trust is spread across three sites, St. George’s Hospital, the base for acute general
medicine and surgical services. The Wolfson Neuro-Rehabilitation Centre in Wimbledon,
and the Bolingbroke Hospital for care of the elderly patients in Battersea. The Trust serves a
local resident population of about 300,000 and sits within the South West London Strategic
Health Authority, which is responsible for a population of approximately 1.25 million. The
Trust serves two local Primary Care Trusts.

In October 2003 the Neurosurgery Unit relocated from the Wimbledon site, sharing new
purpose built PFI accommodation with the regional cardiothoracic unit. The new wing that
neurosciences and cardiothoracic services occupy is called the Atkinson Morley Wing to
keep the association with the prestigious and world renowned hospital.


The Trust Board is chaired by an Independent chair and in addition there are five non-
executive directors from outside the NHS including some from Industry and Commerce. The
Trust is organised in to nine ‘Service Centres’, they are: Therapies, Medical, Cancer,
Surgical, Surgery & Theatres, Children’s & Womens, Cardiothoracic, Neurosciences,
Professional & Scientific and bed management & Emergency Access. Each has a core
management group of a consultant (Chair), senior nurse and general manager. Below is a
list of all the service centres with specialties they encompass:

Dietetics, occupational therapy, physiotherapy, speech and language and the chaplaincy

Medical Services
Intensive Therapy (ITU), Accident & Emergency.chest medicine, clinical haematology,
Clinical Infection Unit, dermatology, diabetes, endocrinology, gastroenterology, endoscopy,
general medicine, geriatric medicine, GUM, HIV/AIDS, hypertension, oncology, renal,
rheumatology and medical records

Cancer Services
Cancer types from all specialties feed in here

Surgery and Theatres
Surgery types:
Head & neck, dentistry, general surgery, plastic surgery, trauma and orthopaedics, urology,
Anaesthetics and operating theatres.

Children’s & Womens
Paediatric medicine and surgery; medical genetics, newborn services, gynaecology,
obstetrics and medical genetics

Cardiothoracic Services
Cardiology; cardiac surgery, thoracic surgery and intensive treatment.
Neuroscience Services
Neurosurgery; neuro intensive care/ pain management, neuroradiology; neurology;
neurorehabilitation, neuroanaesthesia, neuropathology and stroke services.

Professional & Scientific

                                                   Page 9 of 16
Clinical biochemistry; medical microbiology, histopathology; cellular pathology, chemical
pathology, pharmaceutical services; laboratory haematology, medical physics; diagnostic
radiology, PRU/Immunology and breast screening.

Bed Management & Emergency Access
Bed management, social work administration

Operational Management
In addition, the Service Centres are supported by the following Directorates:
Finance, Information and Computing, Human Resources, Operations, Estates and Facilities,

The successful candidate will be expected to work with professional colleagues and local
managers in the efficient running of the Service, and will share with clinical colleagues in the
medical contribution to management. He/she will be expected to participate in the Trusts
system of governance and audit, and maintain their CME/CPD. The appointee will be
expected to observe the Trust’s agreed policies and procedures, drawn up in consultation
with the profession on clinical matters, and to follow the standing orders and financial
instructions of the Trust.

Departmental Facilities

The Neuroscience Unit is managed by the General Manager, who is jointly responsible for
Neurosciences and Cardio-thoracic Services. The Neurosurgical Unit maintains its own
medical records, together with the neuroradiological films, and there is a Medical Records
Officer with associated staff. There is a departmental library in addition to the extensive
library facilities of St. George’s Medical School.

Other Facilities

St. George’s Hospital is based in the heart of Tooting, a popular residential and shopping
area and is well serviced by excellent public transport links to the City and West End.
Tooting Broadway’s Northern Line Underground is a 5 minute walk from the Hospital’s main
entrance, whilst the British Rail station of Tooting Junction is a 10 minute walk away.

                                                   Page 10 of 16
                                    ST GEORGE'S, UNIVERSITY OF LONDON
                                     PERSON SPECIFICATION TEMPLATE

This template shows examples of elements to include in a Person Specification. Please delete these when using this
as a template.

Criteria                                                                             Essential/Desirable           How it is
                                                                                                                   to be

Qualifications                     GMC registration and Licence to Practice             E                         SS, AF
                                   A    National    Training   Number       in
                                   Registration with a recognised Medical
                                    Defence Organisation for insurance and

Experience/Skills                  An intercalated BSc/BA degree in any                 D                         SS, AF,
                                    science subject with honours                                                   INT
                                   An ability to define important biological
                                    problems and use appropriate laboratory-
                                    based methods to solve them
                                   Previous publications in high-impact

AF=Application    Form,    CV=Curriculum       Vitae,    SS=Supporting     Statements,       ST=Selection   Test/Presentation,

Note: Elements marked SS (Supporting Statements) will be used as part of the online application form, and applicants
will be asked to formulate individual supporting statements in response to each of these. Shortlisting will be based on
applicants’ responses to all the individual requirements in the Person Specification above. Therefore applicants are
advised to complete Section 6 (Supporting Statements) in response to the specified criteria, and Section 7 (Additional
Information) in response to additional criteria, as fully as possible on the online application form.

                                                           Page 11 of 16
Brief Summary of Main Terms and Conditions of Post

A full statement of the terms and conditions will be sent to the successful candidate.

Post title:                 Clinical Research Fellow

Contract type:              The post is tenable for a period of one year, in the first
                            instance renewable for a second year subject to satisfactory

Probation period:           Six months

Grade:                      Clinical Lecturer

London allowance:           £2,162 per annum

Salary range:               £30,685 - £32,204 - £33,724 - £35,244 - £37,077 - £38,911 -
                            £40,745 - £42,578 - £44,412 - £49,178 - £53,132 per annum
                            Maximum starting salary will be £37,077

Hours:                      40 hours per week notionally. Staff are expected to work the
                            hours necessary to meet the requirements of the role.

Annual leave:               32 days per annum
                            Plus eight UK public holidays and three days when St
                            George’s is closed (usually between Christmas and New
                            Year). Part time staff receive a pro rata entitlement.

Pension:                    Membership of USS (Universities Superannuation Scheme,
                            employee contribution rate is 6.35%) or of SAUL
                            (Superannuation Arrangements of the University of London,
                            employee contribution rate is 6%) is optional. Existing
                            members of NHSSS (National Health Service Superannuation
                            Scheme) may elect to remain as members of that scheme.

Notice period:              3 months

Offers of                   Offers of appointment are only valid if made by the Director of
employment                  Administration or designated members of the Personnel
                            Office staff acting on his behalf.

                            Offers of appointment are made subject to receipt of
                            satisfactory references and satisfactory completion of
                            probationary periods where appropriate.

Place of residence          It is St George’s policy that all postholders must live within 30
                            miles of St George’s on appointment unless otherwise agreed
                            by Council.

Right to work               St George’s will comply with the Asylum and Immigration Act
                            1996 which requires all employees to provide documentary
                            evidence of their legal right to work in the UK prior to
                            commencing employment. For posts requiring a recognised
                            degree level qualification and where there is no suitable UK

                                                   Page 12 of 16
                            or European Economic Area candidate, St George’s will take
                            necessary steps to secure a work permit from the Home
                            Office in order for a foreign national to take up employment.

                            All candidates invited to interview will be asked to provide
                            copies of one of the following official documents:

                                Copies of the identification pages or appropriate visa
                                 pages of their passport describing the holder as a British
                                 citizen or a EEA national or showing that they are
                                 otherwise entitled to work in the United Kingdom.
                                A birth certificate issued in the UK or in the Republic of
                                A certificate of registration or naturalisation as a British
                                A letter issued by the Immigration and Nationality
                                 Directorate of the Home Office indicating that the person
                                 has permission to take up employment.

                            All successful candidates will be required to provide the
                            originals of one of the above documents on commencing

Medical Clearance           St George’s reserves the right to request successful
                            candidates (including internal candidates) to complete pre-
                            employment health questionnaires. In accordance with this,
                            any offer of employment is made subject to satisfactory health
                            clearance by the Staff Health Department.

No smoking                  St George’s has established a no-smoking policy to minimise
                            risks to the health of staff and to maintain a tobacco smoke
                            free working environment. Smoking is not permitted in any of
                            the St George’s buildings or grounds.

Equal                       St George's, University of London confirms its commitment to
Opportunities               a comprehensive policy of equal opportunities in employment
                            in which individuals are selected and treated on the basis of
                            their relevant merits and abilities and are given equal
                            opportunities within St George’s. The aim of this policy is to
                            ensure that no job applicant or employee should receive less
                            favourable treatment on any grounds not relevant to good
                            employment practice. St George’s is committed to action to
                            make this policy fully effective.

CRB                         Criminal Records Bureau Disclosure

                            This post is subject to the successful candidate being asked
                            to apply for Disclosure from the Criminal Records Bureau
                            (CRB) at Enhanced Level Further information regarding
                            Disclosure can be found at www.disclosure.gov.uk

                            Rehabilitation of Offenders Act 1974

                            Because of the nature of the work for which you are applying,
                            this post is exempt from the provisions of Section 4(2) of the

                                                   Page 13 of 16
                            Rehabilitation of Offenders Act 1974 by virtue of the
                            Rehabilitation of Offenders Act 1974 (Exceptions) Order
                            1975. Applicants are therefore not entitled to withhold
                            information about convictions, which for other purposes are
                            regarded as 'spent' under the provisions of the Act, and in the
                            event of employment, any failure to disclose such convictions
                            could result in dismissal or disciplinary action by St George's,
                            University of London. Convictions within the Armed Services,
                            outside the United Kingdom or disciplinary action by certain
                            professional bodies must also be included.

                            Any information given will be completely confidential and will
                            be considered only in relation to posts to which the Order

GMC Registration            It is a condition of the post that the successful applicant must
                            be registered with the General Medical Council and a Licence
                            to Practice.

Honorary                    If necessary, an Honorary Contract will be sought from the
Contracts                   appropriate Trust for the successful candidate.

Further information about the post

Informal enquiries about the post may be made to Dr Marios Papadopoulos on
mpapadop@sgul.ac.uk or on (020) 8725 5112

Making an application

All applicants are encouraged to apply on line at http://jobs.sgul.ac.uk as our system is user
friendly and the online application form is simple to complete.

Recruitment Team

Tel:     020 8725 5020 (24 hour answerphone)
Fax:     020 8725 3426

Email: jobs@sgul.ac.uk

Closing date: 17th April 2010

Interviews will be held on 30th April 2010

As shortlisted candidates will be notified by email, it is imperative that you provide an email
address that is accessed frequently.

References will be taken up before interview unless you indicate otherwise as part of your

Please quote reference: 411-10

                                                   Page 14 of 16
Thank you for your interest in working at St George’s, University of London. All applicants will be
notified of the outcome of their applications by email (or by post if no email address is supplied). We
aim to respond to all candidates within 5 weeks of the closing date of the vacancy.
                                      St George’s, University of London
                                        RANGE OF STAFF BENEFITS
The following is a list of Staff benefits and facilities:
Pay and Pensions
        Final salary pension schemes (including option to continue existing membership of NHS pension
        Promotion procedure (annual) to recognise increases in responsibilities
        Merit Increments reviews (annual) to recognise and reward outstanding performance
Annual Leave
        Minimum entitlement of 27 days per year and a maximum entitlement of 32 days per year
        8 Bank Holidays
        3 extra statutory days per year (normally between Christmas and New Year, when St George’s is
Work/Life Balance
        Flexible Working (part-time or reduced hours of work, opportunities to work from home for many
         posts, local flexibility in agreeing start and finish times of work)
        Generous maternity leave benefits (8 weeks full pay and 16 weeks half-pay) after completing one
         year's continuous service
        Long term sickness absence pay (rising to 6 months full pay and 6 months half pay after 5 years'
        Adoption and Paternity Leave entitlements
        Paid Time Off for Dependants (compassionate leave or for domestic emergencies)
        Parental Leave
Staff Development Programme
        Personal Development Review (appraisal) scheme for all staff.
        Comprehensive programme of training and development
        Management Development programme
        Learning and Teaching Support programme for teachers of students
        Dedicated programme for Research Staff, including career development, writing for publication
         and planning and managing a research project.
        Departmental and central funding for staff development
        Opportunity to achieve European Computer Driving Licence qualification
Trade Union and Staff Representatives
        Staff Forum for representatives of all staff groups to raise employment issues
        Formal recognition agreements with a number of trade unions
Staff Support
        Occupational Health Service
        Staff counselling and support service
Staff Facilities
        Sports Club (gymnasium, exercise classes, four open squash courts, two aerobics room, one
         resistance machine room and one free weight rooms)
        St George’s Club and Bar
        Interest-free loans for season tickets, car parking permits and costs of training courses.

                                                   Page 15 of 16

A full medical examination will not normally be required. However the successful candidate
will be required to complete a health questionnaire, produce evidence of a satisfactory chest
x-ray within the last year.

Full registration with the General Medical Council will be required.

The Trust will cover all Medical Staff for medical negligence in NHS work under NHS
Indemnity. St. George’s Healthcare NHS Trust is required to encourage Medical and Dental
staff to ensure they have adequate defence cover for any work which does not fall within the
scope of the Indemnity Scheme (HSG (96) 48 refers).

It is a legal requirement for any clinician who personally directs or performs radiological
investigations (other than radiologists) to have attended a recognised course in radiation
protection and possess a Core of Knowledge Certificate.

This includes medical staff who undertake x-ray film in theatre. For radiopharmaceutical
exposures, this includes medical staff who administer radiopharmaceuticals for diagnostic or
therapeutic purposes or who clinically direct.


This post is offered subject to health clearance. The successful candidate will be required to
complete a health questionnaire.

Posts are offered on the understanding that the applicant will comply with the local
requirements regarding immunisations and immunity screening.

Applicants for posts which include Surgical/Invasive work will be asked to supply written
evidence to the Occupational Health Department of degree of immunity to Hepatitis B. (UK
Laboratory reports from blood taken by an Occupational Health Department)
If not immunised the result of a test which indicates freedom from carrier state will be
required and immunisation should then be commenced. Applicants should be aware of the
guidance to HIV infected health care workers from the Department of Health and GMC/GDC.


Whilst the duties of the NHS appointment will be primarily at the hospital(s) stated, the
appointment will be made to the St. George’s Healthcare NHS Trust. There will be a
commitment to attend occasionally at any other hospital or clinic in the Trust, as may be
necessary from time to time, e.g in emergencies.

St. George’s Healthcare NHS Trust is an Equal Opportunities Employer.


Please note that there is a No Smoking Policy within the St. George’s Healthcare NHS Trust.
Staff, patients and visitors are not allowed to smoke in Trust buildings or vehicles.

It is the responsibility of all staff to enforce this policy.

                                                   Page 16 of 16

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