Section 7 Malignant Mesothelioma
Malignant Mesothelioma: Mortality Figure 7-1. Malignant mesothelioma: Number of deaths, crude and age-adjusted death rates, U.S. residents age 15 and over, 1999–2004
3,500 3,000 14 12 10 8 6 4 2 0
Number of Deaths
2,500 2,000 1,500 1,000 500 0
1999
2000
2001
2002
2003
Number of deaths, underlying cause U.S. crude rate
Number of deaths, contributing cause U.S. age-adjusted rate
NOTE: See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, and ICD codes. SOURCE: National Center for Health Statistics multiple cause-of-death data. Population estimates from U.S. Census Bureau.
2004
Rate (Deaths/Million)
171
Malignant Mesothelioma: Mortality Figure 7-2. Malignant mesothelioma: Age-adjusted death rates by state, U.S. residents age 15 and over, 1999–2004
Deaths/Million/Year No. of States 0 > 22.78 25 > 11.39–22.78 25 > 5.70–11.39 ≤ 5.70 1
NOTE: See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, and ICD codes. SOURCE: National Center for Health Statistics multiple cause-of-death data. Population estimates from U.S. Census Bureau.
172
Table 7-1. Malignant mesothelioma: Number of deaths by sex, race, age, median age at death, and anatomical site, U.S. residents age 15 and over, 1999–2004
Year
1999
2000
2001
2002
2003
2004
TOTAL
Anatomical Site Pleura Peritoneum Other Sites Unspecified Any Site Pleura Peritoneum Other Sites Unspecified Any Site Pleura Peritoneum Other Sites Unspecified Any Site Pleura Peritoneum Other Sites Unspecified Any Site Pleura Peritoneum Other Sites Unspecified Any Site Pleura Peritoneum Other Sites Unspecified Any Site Pleura Peritoneum Other Sites Unspecified Any Site 75–84 85+ 86 19 20 6 154 49 644 142 888 213 14 78 21 2 155 50 674 192 918 255 109 29 15 2 148 48 687 187 942 264 80 19 23 3 140 42 741 234 975 295 82 19 26 4 131 42 796 236 1,028 299 77 11 23 2 141 44 867 255 1,097 311 512 111 128 19 869 275 4,409 1,246 5,848 1,637
No. of Deaths 252 92 427 1,751 2,484 225 84 434 1,817 2,531 269 85 389 1,807 2,509 238 95 379 1,902 2,573 206 95 330 2,016 2,625 196 101 326 2,064 2,657 1,386 552 2,285 11,357 15,379
Underlying Sex Race Age Group (yrs) Cause Male Female White Black Other 15–24 25–34 35–44 45–54 55–64 65–74 (%) 90.1 219 33 240 10 2 2 12 32 101 90.2 62 30 90 2 2 10 23 31 90.4 345 82 407 14 6 1 2 3 23 61 134 94.1 1,402 349 1,652 82 17 1 2 26 94 276 566 94.3 1,994 490 2,354 105 25 2 4 33 138 388 818 87.1 188 37 215 7 3 3 6 45 79 91.7 44 40 75 9 3 3 12 11 32 91.9 345 89 412 20 2 1 3 22 58 145 94.2 1,487 330 1,726 73 18 3 25 93 264 566 94.2 2,043 488 2,399 109 23 1 6 34 131 372 814 90.0 217 52 261 5 3 1 10 45 75 88.2 57 28 81 2 2 2 3 2 10 21 30 90.2 310 79 381 8 1 1 4 19 52 116 94.2 1,472 335 1,726 60 21 1 3 32 109 252 536 94.5 2,021 488 2,408 75 26 4 7 39 144 361 748 91.2 195 43 228 7 3 5 12 37 85 82.1 53 42 92 3 1 4 12 20 32 91.6 306 73 362 13 4 2 2 9 9 56 119 94.0 1,605 297 1,808 77 17 1 7 22 76 277 544 94.4 2,126 447 2,449 100 24 3 10 40 106 380 764 87.9 164 42 196 8 2 2 11 30 62 93.7 60 35 91 2 2 1 7 10 23 24 90.3 271 59 311 14 5 1 2 4 14 40 96 94.6 1,644 372 1,908 86 22 3 4 26 115 300 536 94.3 2,125 500 2,484 110 31 4 7 38 148 386 715 89.8 169 27 189 6 1 5 10 39 54 93.1 65 36 95 4 2 8 15 18 35 96.3 265 61 312 8 6 1 6 10 48 76 93.0 1,668 396 1,970 79 15 1 11 24 89 301 516 94.2 2,141 516 2,536 97 24 1 11 42 121 400 674 18 61 228 456 89.4 1,152 234 1,329 43 14 89.9 341 211 524 22 6 2 8 26 69 116 184 91.7 1,842 443 2,185 77 23 6 8 29 97 315 686 94.0 9,278 2,079 10,790 457 110 7 30 155 576 1,670 3,264 94.3 12,450 2,929 14,630 596 153 15 45 226 788 2,287 4,533 Median Age (yrs) 72 70 74 73 73 73 68 74 74 74 75 66 75 74 74 72 69 74 75 74 74 67 75 75 75 73 67 76 76 75 73 68 75 74 74
Malignant Mesothelioma: Mortality
- indicates no deaths listed. NOTE: The sum of individual site death totals may be greater than the total number of deaths for “any site” because some decedents have more than one site of mesothelioma listed on their death certificates. See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, and ICD codes. SOURCE: National Center for Health Statistics multiple cause-of-death data.
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Malignant Mesothelioma: Mortality Table 7-2. Malignant mesothelioma: Death rates (per million population) by race and sex, U.S. residents age 15 and over, 1999–2004
White Year 1999 2000 2001 2002 2003 2004 1999–2004 Overall 11.59 11.40 11.16 11.30 11.41 11.41 11.26 Male 21.92 21.65 21.40 22.09 21.65 21.82 21.54 Black Female 2.02 1.67 1.10 1.28 1.00 1.11 1.34 Male 3.61 3.07 3.66 2.86 3.88 2.66 3.17 Other Female 1.53 1.01 0.81 1.09 1.06 1.03 1.03 Female Male Crude Death Rate 4.95 6.43 4.87 6.84 4.92 4.66 4.39 6.28 4.96 7.25 5.06 5.99 4.82 6.17
Age-Adjusted Death Rate 1999 2000 2001 2002 2003 2004 1999–2004 11.64 11.59 11.32 11.44 11.48 11.44 11.39 23.88 24.22 23.83 24.54 23.84 23.95 23.84 4.29 4.20 4.23 3.73 4.20 4.30 4.13 10.32 10.96 7.53 10.61 11.54 10.19 10.10 2.57 2.02 1.32 1.56 1.24 1.27 1.63 6.47 5.44 6.68 5.11 6.56 4.71 5.61 2.18 1.30 1.10 1.31 1.38 1.27 1.35
NOTE: See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, and ICD codes. SOURCE: National Center for Health Statistics multiple cause-of-death data. Population estimates from U.S. Census Bureau.
174
Malignant Mesothelioma: Mortality Table 7-3. Malignant mesothelioma: Years of potential life lost to age 65 and to life expectancy by race and sex, U.S. residents age 15 and over, 1999–2004
Year 1999 2000 2001 2002 2003 2004 TOTAL White Male Female 3,390 3,065 3,385 3,450 3,505 3,445 20,240 1,205 1,340 1,460 1,055 1,325 1,365 7,750 Black Male Female 320 260 270 295 520 275 1,940 95 110 85 110 30 125 555 Other Male Female 25 75 125 15 85 45 370 30 80 40 50 60 40 300 Total 5,065 4,930 5,365 4,975 5,525 5,295 31,155
Years of Potential Life Lost to Age 65
Years of Potential Life Lost to Life Expectancy 1999 2000 2001 2002 2003 2004 TOTAL 23,515 23,502 23,975 24,937 25,059 25,452 146,440 7,120 7,137 7,417 6,346 7,512 7,813 43,345 1,060 1,137 844 1,074 1,467 1,075 6,657 408 407 300 341 217 344 2,017 230 295 371 231 400 254 1,781 132 159 105 155 151 141 843 32,465 32,637 33,012 33,084 34,806 35,079 201,083
NOTE: See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, and ICD codes. SOURCE: National Center for Health Statistics multiple cause-of-death data.
175
Malignant Mesothelioma: Mortality
Table 7-4. Malignant mesothelioma: Number of deaths by state, U.S. residents age 15 and over, 1999–2004
State Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming TOTAL 1999 33 8 32 15 259 17 33 12 5 163 30 5 14 128 58 21 27 24 47 28 51 81 69 61 20 49 10 15 22 11 111 17 156 56 4 131 22 32 161 14 26 4 31 125 9 7 75 72 29 49 5 2,484 2000 29 4 39 11 263 29 18 10 2 173 41 4 13 129 51 23 29 32 54 23 53 96 107 59 7 50 13 16 12 15 102 20 136 49 3 105 26 50 161 9 42 8 34 119 20 2 79 76 18 60 7 2,531 2001 24 3 42 10 235 32 36 12 2 184 40 14 9 124 49 24 24 38 39 22 55 76 93 45 18 37 13 17 13 18 103 7 161 46 10 111 19 59 159 10 28 5 44 129 13 6 72 77 25 73 4 2,509 2002 39 5 39 14 244 29 36 8 3 165 34 8 13 126 53 37 22 25 38 23 49 77 93 49 20 56 12 19 19 13 133 13 159 52 10 121 21 30 156 15 26 4 49 127 23 7 75 84 26 66 8 2,573 2003 41 5 43 10 259 29 46 9 3 198 35 8 11 120 63 20 19 23 50 29 49 68 100 72 21 38 13 16 16 15 112 10 138 61 7 136 28 51 180 11 30 7 32 135 10 3 70 77 21 71 6 2,625 2004 26 5 38 17 248 27 42 14 3 177 39 6 8 125 58 26 17 27 50 26 63 85 96 59 14 48 10 15 17 14 113 14 143 61 4 122 25 42 193 8 25 6 46 155 18 4 85 80 30 69 14 2,657 Total 192 30 233 77 1,508 163 211 65 18 1,060 219 45 68 752 332 151 138 169 278 151 320 483 558 345 100 278 71 98 99 86 674 81 893 325 38 726 141 264 1,010 67 177 34 236 790 93 29 456 466 149 388 44 15,379
NOTE: See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, and ICD codes. SOURCE: National Center for Health Statistics multiple cause-of-death data.
176
Malignant Mesothelioma: Mortality
Table 7-5. Malignant mesothelioma: Number of deaths, death rates (per million population), and years of potential life lost (YPLL) by state, U.S. residents age 15 and over, 1999–2004
No. of Deaths Rank State Alabama 192 25 Alaska 30 49 Arizona 233 22 Arkansas 77 40 California 1,508 1 Colorado 163 28 Connecticut 211 24 Delaware 65 44 District of Columbia 18 51 Florida 1,060 2 Georgia 219 23 Hawaii 45 45 Idaho 68 42 Illinois 752 6 Indiana 332 15 Iowa 151 29 Kansas 138 33 Kentucky 169 27 Louisiana 278 18 Maine 151 29 Maryland 320 17 Massachusetts 483 10 Michigan 558 9 Minnesota 345 14 Mississippi 100 34 Missouri 278 18 Montana 71 41 Nebraska 98 36 Nevada 99 35 New Hampshire 86 38 New Jersey 674 8 New Mexico 81 39 New York 893 4 North Carolina 325 16 North Dakota 38 47 Ohio 726 7 Oklahoma 141 32 Oregon 264 20 Pennsylvania 1,010 3 Rhode Island 67 43 South Carolina 177 26 South Dakota 34 48 Tennessee 236 21 Texas 790 5 Utah 93 37 Vermont 29 50 Virginia 456 12 Washington 466 11 West Virginia 149 31 Wisconsin 388 13 Wyoming 44 46 Death Rate Crude 8.97 10.28 9.22 5.97 9.25 7.66 12.88 16.67 6.32 13.10 5.48 7.52 10.94 12.69 11.45 10.64 10.74 8.48 13.22 23.52 12.38 15.45 11.74 14.40 7.44 10.25 16.09 11.94 9.77 14.02 16.50 9.35 9.72 8.23 12.28 13.39 8.48 15.64 16.86 12.81 8.95 9.41 8.50 7.89 9.02 9.59 13.08 16.12 16.74 14.87 18.30 Rank 39 29 37 50 36 46 18 5 49 16 51 47 26 20 25 28 27 42 15 1 21 10 24 12 48 30 8 23 31 13 6 35 32 44 22 14 42 9 3 19 40 34 41 45 38 33 17 7 4 11 2 Age-Adjusted 8.74 21.66 8.98 5.55 10.53 9.46 11.76 16.57 6.70 10.28 6.87 7.07 11.55 13.19 11.53 9.50 10.32 8.67 13.91 21.38 13.41 14.73 11.85 14.86 7.67 9.83 15.07 11.36 10.83 14.76 15.81 9.58 9.57 8.56 11.06 12.73 8.21 15.35 14.25 11.80 9.25 8.37 8.59 9.47 11.98 9.33 14.42 17.52 14.56 14.58 19.07 Rank 41 1 40 51 29 37 23 5 50 31 49 48 24 18 25 35 30 42 16 2 17 11 21 9 47 32 8 26 28 10 6 33 34 44 27 19 46 7 15 22 39 45 43 36 20 38 14 4 13 12 3 Total 2,785 406 3,156 1,268 21,437 2,444 2,827 811 286 14,181 3,296 622 971 10,605 4,733 2,163 1,807 2,530 4,406 2,049 4,522 6,308 7,986 4,680 1,555 3,906 988 1,359 1,504 1,162 8,553 1,250 12,261 4,820 546 9,948 2,048 3,598 13,289 916 2,446 424 3,782 11,538 1,414 489 6,459 6,061 2,181 5,313 640 YPLL to Life Expectancy Rank 25 50 23 38 1 28 24 44 51 2 22 46 42 6 15 30 33 26 18 31 17 11 9 16 34 19 41 37 35 40 8 39 4 14 47 7 32 21 3 43 27 49 20 5 36 48 10 12 29 13 45 YPLL/death Rank 14.5 16 13.5 40 13.5 40 16.5 2 14.2 24 15.0 10 13.4 43 12.5 50 15.9 4 13.4 43 15.0 10 13.8 31 14.3 20 14.1 26 14.3 20 14.3 20 13.1 46 15.0 10 15.9 4 13.6 37 14.1 26 13.1 46 14.3 20 13.6 37 15.5 6 14.0 28 13.9 29 13.9 29 15.2 8 13.5 40 12.7 49 15.4 7 13.7 33 14.8 13 14.4 19 13.7 33 14.5 16 13.6 37 13.2 45 13.7 33 13.8 31 12.5 50 16.0 3 14.6 14 15.2 8 16.8 1 14.2 24 13.0 48 14.6 14 13.7 33 14.5 16
NOTE: See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, and ICD codes. SOURCE: National Center for Health Statistics multiple cause-of-death data. Population estimates from U.S. Census Bureau.
177
Malignant Mesothelioma: Mortality Table 7-6. Malignant mesothelioma: Most frequently recorded industries on death certificate, U.S. residents age 15 and over, selected states, 1999
CIC 060 961 842 192 901 010 392 460 400 831 Industry Number of Deaths Construction 77 Non-paid worker or non-worker or own home/at home 38 Elementary and secondary schools 20 Industrial and miscellaneous chemicals 19 General government, n.e.c. 13 Agricultural production, crops 10 Not specified manufacturing industries 10 Electric light and power 10 Railroads 9 Hospitals 9 All other industries 303 Industry not reported 23 TOTAL 541 Percent 14.2 7.0 3.7 3.5 2.4 1.9 1.9 1.9 1.7 1.7 56.0 4.3 100.0
CIC - Census Industry Code n.e.c. - not elsewhere classified NOTE: The comparable number of malignant mesothelioma deaths in the entire United States for this same time period was 2,484. Percentages may not total to 100% due to rounding. See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, ICD codes, industry and occupation codes, and list of selected states. SOURCE: National Center for Health Statistics multiple cause-of-death data.
Table 7-7. Malignant mesothelioma: Most frequently recorded occupations on death certificate, U.S. residents age 15 and over, selected states, 1999
COC 019 914 585 453 243 567 156 473 575 633 804 Occupation Managers and administrators, n.e.c. Housewife/Homemaker Plumbers, pipefitters, and steamfitters Janitors and cleaners Supervisors and proprietors, sales occupations Carpenters Teachers, elementary school Farmers, except horticulture Electricians Supervisors, production occupations Truck drivers All other occupations Occupation not reported TOTAL Number of Deaths 41 37 18 17 16 16 13 12 12 12 12 307 28 541 Percent 7.6 6.8 3.3 3.1 3.0 3.0 2.4 2.2 2.2 2.2 2.2 56.8 5.2 100.0
COC - Census Occupation Code n.e.c. - not elsewhere classified NOTE: The comparable number of malignant mesothelioma deaths in the entire United States for this same time period was 2,484. See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, ICD codes, industry and occupation codes, and list of selected states. SOURCE: National Center for Health Statistics multiple cause-of-death data.
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Malignant Mesothelioma: Mortality Table 7-8. Malignant mesothelioma: Proportionate mortality ratio (PMR) adjusted for age, sex, and race by usual industry, U.S. residents age 15 and over, selected states, 1999
CIC 360 192 200 460 060 Industry Ship and boat building and repairing Industrial and miscellaneous chemicals Petroleum refining Electric light and power Construction Number of Deaths 7 19 5 10 77 PMR 6.0 4.8 3.8 3.1 1.6 95% Confidence Interval LCL UCL 2.4 12.3 2.9 1.2 1.5 1.2 7.5 8.9 5.7 1.9
CIC - Census Industry Code LCL - lower confidence limit UCL - upper confidence limit NOTE: The total number of deaths with malignant mesothelioma reported was 541 in these same selected states and years, and the comparable number of malignant mesothelioma deaths in the entire United States for this same time period was 2,484. See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, ICD codes, industry and occupation codes, and list of selected states. SOURCE: National Center for Health Statistics multiple cause-of-death data.
Table 7-9. Malignant mesothelioma: Proportionate mortality ratio (PMR) adjusted for age, sex, and race by usual occupation, U.S. residents age 15 and over, selected states, 1999
CO C 585 057 575 156 Occupation Plumbers, pipefitters, and steamfitters Mechanical engineers Electricians Teachers, elementary school Number of Deaths 18 6 12 13 PMR 4.8 3.0 2.4 2.1 95% Confidence Interval LCL UCL 2.8 7.5 1.1 1.3 1.1 6.6 4.2 3.6
COC - Census Occupation Code LCL - lower confidence limit UCL - upper confidence limit NOTE: The total number of deaths with malignant mesothelioma reported was 541 in these same selected states and years, and the comparable number of malignant mesothelioma deaths in the entire United States for this same time period was 2,484. See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, ICD codes, industry and occupation codes, and list of selected states. SOURCE: National Center for Health Statistics multiple cause-of-death data.
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180
Deaths/Million/Year No. of Counties* > 22.78 124 293 > 11.39–22.78 > 5.70–11.39 158 ≤ 5.70 19
Malignant Mesothelioma: Mortality
Figure 7-3. Malignant mesothelioma: Age-adjusted death rates by county, U.S. residents age 15 and over, 2000–2004
*Age-adjusted rates have not been calculated for counties having less than 5 deaths with the disease of interest or for unincorporated counties (see Appendix H). NOTE: See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, and ICD codes. SOURCE: National Center for Health Statistics multiple cause-of-death data. Population estimates from U.S. Census Bureau.
Malignant Mesothelioma: Mortality Table 7-10. Malignant mesothelioma: Counties with highest age-adjusted death rates (per million population), U.S. residents age 15 and over, 2000–2004
County Sagadahoc County Koochiching County Lincoln County Mason County Carlton County Lincoln County Bonner County Washington County Newport News City Kitsap County Posey County York County Dickinson County Tooele County Union County Tyler County Jasper County Isle of Wight County Jefferson Parish Somerset County Portsmouth City Mason County Martin County Orange County Hancock County Houghton County Gloucester County Franklin County Alpena County Delaware County Anchorage Borough Yuba County Polk County Gloucester County Kenosha County Niagara County Mason County Augusta County James City County Preble County Greenup County Natrona County Jackson County Chesapeake City Clinton County Windham County Hill County Cattaraugus County Siskiyou County St. Louis County Overall United States State Maine Minnesota Montana West Virginia Minnesota Maine Idaho Maine Virginia Washington Indiana Virginia Michigan Utah Oregon Texas Indiana Virginia Louisiana New Jersey Virginia Washington Minnesota Texas West Virginia Michigan Virginia Washington Michigan Oklahoma Alaska California Wisconsin New Jersey Wisconsin New York Michigan Virginia Virginia Ohio Kentucky Wyoming Mississippi Virginia Illinois Connecticut Texas New York California Minnesota Age-Adjusted Rate 97.1 77.5 56.1 55.6 55.3 55.0 50.7 50.3 49.2 48.0 47.8 47.2 47.0 46.9 45.5 44.7 43.3 42.8 42.1 41.0 40.5 39.6 38.6 38.4 38.0 37.7 37.5 37.4 36.4 35.7 35.6 34.8 34.8 34.8 34.4 34.3 34.2 34.1 33.8 33.6 33.4 32.9 32.5 32.3 32.2 31.9 31.7 31.5 31.3 31.3 11.5 Crude Rate 102.6 104.5 65.1 65.7 60.5 76.0 58.2 64.7 42.4 43.1 46.9 38.8 63.1 36.3 50.4 59.3 41.5 40.1 41.7 37.2 43.6 47.7 57.5 39.2 52.4 40.3 35.0 26.2 47.1 45.8 13.7 30.2 40.7 32.7 31.5 40.9 42.8 33.0 42.6 35.3 39.5 33.5 27.0 23.9 34.7 31.6 37.4 35.9 44.2 38.4 11.3 Number of Deaths 15 6 5 7 8 11 9 9 29 40 5 9 7 6 5 5 5 5 75 45 17 10 5 13 7 6 5 5 6 7 14 7 7 34 19 36 5 9 9 6 6 9 14 19 5 14 5 12 8 32 12,895 % Female 26.7 0.0 40.0 14.3 0.0 9.1 11.1 11.1 6.9 20.0 60.0 11.1 28.6 16.7 40.0 0.0 40.0 20.0 34.7 33.3 29.4 0.0 0.0 7.7 14.3 50.0 0.0 20.0 16.7 28.6 0.0 28.6 0.0 11.8 26.3 16.7 20.0 11.1 22.2 50.0 33.3 0.0 21.4 5.3 40.0 35.7 20.0 25.0 12.5 6.3 18.9
NOTE: Only counties with at least 5 deaths from the disease of interest are included. See selected limitations for general cautions regarding inferences based on small numbers of deaths, and see appendices for source description, methods, and ICD codes. SOURCE: National Center for Health Statistics multiple cause-of-death data. Population estimates from U.S. Census Bureau.
181