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					                                            Curriculum Vitae

                                              Nancy J. Cox

Office Address:
The University of Chicago
Department of Medicine
Section of Genetic Medicine
5841 South Maryland Avenue
M265 ~ MC 6091
Chicago, IL 60637
Phone: (773) 834-1001
Fax: (773) 834-0505

Marital Status
Married, 2 children

1978 B.Sc. Biology, The University of Notre Dame
1982 Ph.D. Human Genetics, Yale University

Professional Positions Held:
1982-1985     Postdoctoral Fellow in Genetic Epidemiology Department of Psychiatry, Washington
              University School of Medicine, St. Louis, MO
1985-1987     Research Associate, Department of Human Genetics, The University of Pennsylvania School
              of Medicine, Philadelphia, PA
1987-1990     Research Associate, Howard Hughes Medical Institute, The University of Chicago
1988-1990     Research Associate (Assistant Professor), Department of Medicine, The University of Chicago
1990-1996     Chief Research Technician, Department of Medicine, The University of Chicago
1996-1999     Research Associate (Assistant Professor), Department of Medicine, The University of Chicago
1999-2004     Associate Professor, Departments of Human Genetics and Medicine, The University of Chicago
2004-Present Professor, Departments of Human Genetics and Medicine, The University of Chicago
2005-Present Professor and Chief, Section of Genetic Medicine, Dept. of Medicine, The University of Chicago

Honors and Awards:
Notre Dame Scholar, The University of Notre Dame, 1974-1978
Central Illinois Public Service Company Scholarship Award, 1974-1978
Notre Dame Scholarship, The University of Notre Dame, 1977-1978
National Research Service Award, Yale University, 1978-1981

Professional Activities:
National Editorial Board - Diabetes 1993-1996
Member of Congressionally Mandated Diabetes Working Group 1998-1999
Member of Mammalian Genetics Study Section 1999-2003
Genetics Advisory Committee, NIDDK Phoenix, 1999-present
Scientific Advisory Board, Joslin Diabetes Center, 2000-2003

Curriculum Vitae (cont.)
Nancy J. Cox
External Review Committee, Department of Human Genetics, The University of Utah, 2001
American Society of Human Genetics National Program Committee 2002-2004
American Diabetes Association National Program Committee 2004-present
Chair, Data Safety Monitoring Board, NHLBI Gene X Environment Studies, 2003-2006
Board of Scientific Counselors for NHGRI 2003-2008
Editor-in-Chief, Genetic Epidemiology 2006-2011
Editorial Board, American Journal of Human Genetics 2006-2009

University Service:
The University of Chicago Admissions Committee Molecular Biosciences Cluster 1999-2003, Chair 2003
Committee on Research Resources 1999-2003
Aims Scientific Committee 2003
Steering Committee for Committee on Genetics 2001- present
Director of Graduate Studies and Curriculum Committee, Department of Human Genetics, 2002-2005
Committee on Academic Promotions 2004-2006

Membership in Professional and Scientific Societies:
American Society of Human Genetics
International Society of Genetic Epidemiology
American Diabetes Association

Grant Support
09/15/06 – 09/14/09 NIH/NIDDK $340,234 15% effort ―Genetic Studies of Diabetic Complications‖, (P.I.
Nancy J. Cox)
06/15/06-05/31/09 NIH/NHLBI $188,419, 5% effort, ―Genome-wide Association Mapping of Metabolic, Lung,
and Cardiovascular Phenotypes‖, (P.I. Nancy J. Cox)
05/15/06-04/30/08, NIH/NIDDK, $133,137, 10% effort, ―Copy-number Polymorphism Análysis of the Type 2
Diabetes Gene Calpain 10‖, (P.I. Nancy J. Cox)
07/01/00 – 06/30/08, NIH/NIDCD $100,000, 10% effort, ―Stuttering: A Linkage Analysis‖, (P.I. Nancy J. Cox)
01/01/07 – 12/31/09 NIH/NIDCD $150,000, 10% effort, ―Identification of Sex-Specific Genes for Stuttering‖,
(P.I. Nancy J. Cox)

Human Genetics GEN 470, Course Director/6 lectures per year, 1998-2001
Human Variations 469, 6 lectures per year, 2001
Introduction to Statistical Genetics 471, 17 lectures per year, 2002-present

Postdoctoral Fellow Trainees
Susan Colilla, Ph.D., 1998-2002, currently in Epidemiology and Public Health, The University of Pennsylvania
Anya Tsalenko, Ph.D., 1997-2001, currently with Agilent Technologies
Anna Pluzhnikov, Ph.D., 1999-2001, currently Laboratory Manager, Department of Human Genetics, The
University of Chicago
Mark Abney, Ph.D., 1997-2001, currently Research Associate (Assistant Professor), Department of Human
Genetics, The University of Chicago
Marcos Antezana, Ph.D., 2003–2004, currently Research Associate, Department of Ecology & Evolution, The

Curriculum Vitae (cont.)
Nancy J. Cox
University of Chicago
Yu-Sheng Chen, Ph.D., 2003-2005
Maggie Ng, Ph.D., 2003-2006, currently Assistant Professor, Chinese University of Hong Kong
M. Geoffrey Hayes, Ph.D., 2002-2007, currently Assistant Professor, Northwestern University

Anna Tikhomirov, Ph.D.

Graduate/Undergraduate Student Trainees
Nicoline Ambrose, PhD, 1996, currently Associate Professor, Department of Speech and Hearing Sciences, The
University of Illinois at Champaign-Urbana
Benjamin Voight, Ph.D., 2006, currently post-doctoral fellow, the Broad Institute, Boston, MA
Jaqueline K. Wittke-Thompson, 2006

Jennifer (Piper) Below

Peer Reviewed Articles:
1.    Cox, N.J. & Kidd, K.K. (1983) Can recovery from stuttering be considered a genetically milder subtype
      of stuttering? Behav Genet 13:129-139.
2.    Dorus, E., Cox, N.J., Gibbon, R.D., Shaughnessy, R., Pandey, G.N. & Cloninger, C.R. (1983) Lithium
      ion transport and affective disorders within families of bipolar patients: Identification of a major gene
      locus. Arch Gen Psychiat 40:545-552.
3.    Cox, N.J., Seider, R.A. & Kidd, K.K. (1984) Some environmental factors and hypotheses for stuttering
      in families with several stutterers. J Speech Hear Res 27:543-548.
4.    Cox, N.J. (1984) Genetic Analysis Workshop II: Results of segregation analyses using POINTER and
      linkage analyses using LIPED. Genet Epidem 1:167-170.
5.    Cox, N.J., Kramer, P.L. & Kidd, K.K. (1984) Segregation analyses of stuttering. Genet Epidem 1:245-
6.    Goldin, L.R., Cox, N.J., Pauls, D.L., Gershon, E.L. & Kidd, K.K. (1984) The detection of major loci by
      segregation and linkage analysis: A simulation study. Genet Epidem 1:285-296.
7.    Cox, N.J. & Suarez, B.K. (1985) Genetic Analysis Workshop III: Two-point linkage analysis on
      pedigrees, nuclear families, sibships. Genet Epidem 2:205-206.
8.    Suarez, B.K. & Cox, N.J. (1985) Linkage analysis for psychiatric disorders. I. Basic concepts. Psychiat
      Dev 3:219-243.
9.    Cox, N.J. & Suarez, B.K. (1985) Linkage analysis for psychiatric disorders. II. Methodological
      considerations. Psychiat Dev 4:369-382.
10.   Ewens, W.J., Shute, N.C.E., Cox, N.J., Price, R.A. & Spielman, R.S. (1986) Ascertainment
      considerations in the analysis of affected sib shared haplotype data. Genet Epidem Suppl 1:319-322.
11.   Cox, N.J., Xiang, K., Bell, G.I. & Karam, J.H. (1988) Glucose transporter gene and non-insulin-
      dependent diabetes. Lancet II:793-794 (letter).
12.   Vinik, A.I., Cox, N.J., Xiang, K-S., Fajans, S.S. & Bell, G.I. (1988) Linkage studies of maturity onset
      diabetes of the young -- R.W. pedigree. Diabetologia 31:778-780 (letter).
13.   Cox, N.J., Baker, L. & Spielman, R.S. (1988) Insulin gene sharing in sib pairs with insulin-dependent
      diabetes mellitus: No evidence for linkage. Am J Hum Genet 42:167-172.

Curriculum Vitae (cont.)
Nancy J. Cox
14.    Price, R.A., Cox, N.J., Spielman, R.S., Van Loon, J.A., Maidak, B.L. & Weinshilboum, R.M. (1988)
       Inheritance of human platelet thermolabile phenol sulfotransferase (TL PST) activity. Genet Epidem 5:1-
15.    Cox, N.J., Hodge, S.E., Marazita, M.L., Spence, M.A. & Kidd, K.K. (1988) Some effects of selection
       strategies on linkage analysis. Genet Epidem 5:289-297.
16.    Cox, N.J., Bell, G.I. & Xiang, K. (1988) Linkage disequilibrium in the insulin/insulin-like growth factor
       II region of human chromosome 11. Am J Hum Genet 43:495-501.
17.    Cox, N.J., Mela, A.P., Zmijewski, C.M. & Spielman, R.S. (1988) HLA-DR typing "at the DNA level":
       RFLP's and subtypes detected with a DR-beta cDNA probe. Am J Hum Genet 43:954-963.
18.    Rajput-Williams, J., Knott, T.J., Wallis, S.C., Sweetnam, P., Yarnell, J., Cox, N.J., Bell, G.I., Miller,
       N.E. & Scott, J. (1988) Variation of apolipoprotein-B gene is associated with obesity, elevated blood
       cholesterol levels and coronary heart disease. Lancet ii:1442-1446.
19.    Xiang, K.S., Bell, G.I., Karam, J.H., Cox, N.J., Sanz, N. & Huang, P. (1988) The association of genes
       responsible for carbohydrate and lipid metabolism in Chinese with non-insulin-dependent diabetes
       mellitus. J Chinese Med 68:552-556 [in Chinese].
20.    Baur, M.P., Fimmers, R., Fritsche, R., et al. (1989) Genetic analysis of insulin-dependent diabetes
       mellitus (IDDM): The GAW5 multiplex family dataset. Genet Epidem 6:15-20.
21.    Cox, N.J., Gogolin, K.J., Horvath, V.J., Barker, D.F., Wright, E., Tran, T., Skolnick, M.H., Boehm,
       B.O., Fehsel, K., Bertrams, J., Hodge, T.W., Acton, R.T., McGill, J., Elbein, S.C., Permutt, M.A., de
       Preval, C., Avoustin, P., Cambon-Thomsen, A., Robinson, D.M., Holbeck, S.L., Nepom, G.T.,
       Schneider, P.M., Rittner, C., Toyoda, H., Rotter, J.I. & Spielman, R. (1989) Restriction fragment
       polymorphisms of the HLA-DR, HLA-DQ and insulin gene regions in insulin-dependent diabetes
       mellitus families: The Genetic Analysis Workshop 5 data. Genet Epidem 6:21-26.
22.    Cox, N.J. & Spielman, R.S. (1989) The insulin gene and susceptibility to IDDM. Genet Epidem 6:65-
23.    Xiang, K., Cox, N.J., Sanz, N., Huang, P., Karam, J.H. & Bell, G.I. (1989) Insulin receptor and
       apolipoprotein genes contribute to the development of non-insulin-dependent diabetes mellitus in
       Chinese Americans. Diabetes 38:17-23.
24.    Cox, N.J., Epstein, P.A. & Spielman, R.S. (1989) Linkage studies on non-insulin-dependent diabetes
       mellitus (NIDDM) and the insulin and insulin receptor genes. Diabetes 38:653-658.
25.    Cox, N.J., Reich, T., Rice, J., Elston, R., Scober, J., Keats, B. (1989) Segregation and linkage analyses
       of bipolar and major depressive illnesses in multigenerational pedigrees. J Psychiat Res 23:109-123.
26.    Cox, N.J. & Bell, G.I. (1989) Disease associations: Chance, artifact, or susceptibility genes? Diabetes
27.    Matsutani, A., Koranyi, L., Cox, N.J. & Permutt, M.A. (1990) Polymorphisms of GLUT2 and GLUT4
       genes: use in evaluation of genetic susceptibility to NIDDM in Blacks. Diabetes 39:1534-1542.
28.    Bell, G.I., Wu, S., Newman, M., Fajans, S.S., Seino, M., Seino, S. & Cox, N.J. (1991) Diabetes
       mellitus: Identification of susceptibility genes. In "Etiology of Human Disease at the DNA Level", edited
       by Lindsten J, and Pettersson U, Raven Press, New York, pp. 93-113.
29.    Bell, G.I., Xiang, K., Newman, M.V., Wu, S., Wright, L.G., Fajans, S.S., Spielman, R.S. & Cox, N.J.
       (1991) Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype)
       is linked to DNA polymorphism on human chromosome 20q. Proc Natl Acad Sci USA 88:1484-1488.
30.    Mangklabruks, A., Billerbeck, A-E., Wajchenberg, B., Knobel, M., Cox, N.J., DeGroot, L.J. &
       Medeiros-Neto, G. (1991) Genetic linkage studies of thyroid peroxidase (TPO) gene in families with
       TPO deficiency. J Clin Endocrinol Metab 72:471-476.

Curriculum Vitae (cont.)
Nancy J. Cox
31.    Mangklabruks, A., Cox, N.J. & DeGroot, L. (1991) Genetic factors in autoimmune thyroid disease
       analyzed by restriction fragment length polymorphisms of candidate genes. J Clin Endocrinol Metab
32.    Kong, A., Frigge, M., Cox, N.J. & Wong, W.H. (1992) Linkage analysis with adjustment for covariates:
       A method combining peeling with Gibbs sampling. Genetic Analysis Workshop 7: Issues in Gene
       Mapping and Detection of Major Genes. MacCluer JW, Chakravarti A, Cox D, Bishop DT, Bale SJ,
       Skolnick MH (eds.) Cytogenet Cell Genet 59:208-211.
33.    Cox, N.J., Xiang, K.S., Fajans, S.S. & Bell, G.I. (1992) Mapping diabetes-susceptibility genes: Lessons
       learned from the search for a DNA marker for MODY. Diabetes 41:401-407.
34.    Kong, A., Frigge, M., Irwin, M. & Cox, N.J. (1992) Importance sampling. I. Computing multi-model p
       values in linkage analysis. Am J Hum Genet 51:1413-1429.
35.    Cox, N.J. (1993) Stuttering: A complex behavioral disorder for our times? Am J Med Genet
       (Neuropsychiatric Genetics) 48:177-178.
36.    Stoffel, M., Xiang, K.S., Espinosa, III R., Cox, N.J., LeBeau, M.M. & Bell, G.I. (1993) cDNA sequence
       and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to
       choromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young. Hum
       Mol Genet 2:1-4.
37.    Lewis, B.A., Cox, N.J. & Byard, P.J. (1993) Segregation analysis of speech and language disorders.
       Behav Genet 23:291-297.
38.    Ambrose, N., Yairi, E. & Cox, N.J. (1993) Genetic aspects of early childhood stuttering. J Speech Hear
       Res 36:701-706.
39.    Kong, A., Irwin, M., Cox, N.J. & Frigge, M. (1993) Sequential imputation in multilocus linkage
       analysis. Genet Epidemiol 10:483-488.
40.    Cox, N.J. (1994) Maternal component in NIDDM transmission: How large an effect? Diabetes 43:166-
41.    Kass, S., MacRae, C., Graber, H.L., Sparks, E.A., McNamara, D., Boudoulas, H., Basson, C.T., Baker,
       P.B. III, Cody, R.J., Fishman, M.C., Cox, N.J., Kong, A., Wooley, C.F., Seidman, J.G. & Seidman, C.E.
       (1994) A gene defect that causes conduction system disease and dilated cardiomyopathy maps to
       chromosome 1p1-1q1. Nature Genet 7:546-551.
42.    Irwin, M., Cox, N.J. & Kong, C.A. (1994) Sequential imputation for multilocus linkage analysis. Proc
       Natl Acad Sci USA 91:11684-11688.
43.    Weiss, R.E., Sunthornthepvarakul, T., Angkeow, P., Marcus-Bagley, D., Cox, N.J., Alper, C.A. &
       Refetoff, S. (1994) Linkage of familial dysalbuminemic hyperthyroxinemia to the albumin gene in a
       large Amish kindred. J Clin Endocrinol Metab 80:116-121.
44.    Cook, E.H., Stein. M.A., Krasowski, M.D., Cox, N.J., Olkon, D.M., Keiffer, J.E. & Leventhal, B.L.
       (1995) Association of attention-deficit disorder and the dopamine transporter gene. Am J Hum Genet
45.    Tsaar, M.L., Menzel, S., Lai, F.P., Espinosa, III R., Concannon, P., Spielman, R.S., Hanis, C.L., Cox,
       N.J., Le Beau, M.M., German, M.S., Jan, L.Y., Bell, G.I. & Stoffel, M. (1995) Isolation of a cDNA
       clone encoding a KATP-channel-like protein expressed in insulin-secreting cells, localization of the
       human gene to chromosome band 21q22.1, and linkage studies with NIDDM. Diabetes 44:592-596.
46.    Glaser, B., Chiu, K.C., Liu, L., Anker, R., Nestorowicz, A., Cox, N.J., Landau, H., Kaiser, N., Thornton,
       P.S., Stanley, C.A., Cerasi, E., Baker, L., Donis-Keller, H. & Permutt, M.A. (1995) Recombinant
       mapping of the familial hyperinsulinism gene to an 0.8 cM region on chromosome 11p15.1 and
       demonstration of a founder effect in Ashkenazi Jews. Hum Mol Genet 4:879-886.

Curriculum Vitae (cont.)
Nancy J. Cox
47.    Stirling, B., Cox, N.J., Bell, G.I., Hanis, C.L., Spielman, R.S. & Concannon, P. (1995) Identification of
       microsatellite markers near the human ob gene and linkage studies in NIDDM affected sib pairs.
       Diabetes 44:999-1001.
48.    Menzel, S., Yamagata, K., Trabb, J.B., Nerup, J., Permutt, M.A., Fajans, S.S., Menzel, R., Iwasaki, N.,
       Omori, Y., Cox, N.J. & Bell, G.I. (1995) Localization of MODY3 to a 5 cM region of human
       chromosome 12. Diabetes 44:1408-1413.
49.    Stirling, B., Cox, N.J., Bell, G.I., Hanis, C.L., Spielman, R.S. & Concannon, P. (1995) Linkage studies in
       NIDDM with markers near the sulfonylurea receptor gene. Diabetologia 38:1479-1481.
50.    Shoulders, C.C., Grantham, T.T., North, J.D., Gaspardone, A., Tomai, F., DeFazio, A., Versaci, F., Gioffre,
       P.A. & Cox, N.J. (1996) Hypertriglyceridemia and the apolipoprotein III gene locus: lack of association with
       the variant insulin response element in Italian school children. Hum Genet 98:557-566.
51.    Iwasaki, N., Kawamura, M., Yamagata, K., Cox, N.J., Karibe, S., Ohgawara, H., Inagaki, N., Seino, S.,
       Bell, G.I. & Omori, Y. (1996) Identification of microsatellite markers near the human genes encoding
       the β-cell ATP-sensitive potassium channel and linkage studies with NIDDM in Japanese. Diabetes
52.    Gambino, V., Menzel, S., Trabb, J.B., Xiang, K.S., Lindner, T., Louït, A., Chen, E., Mereu, L.E., Furuta,
       H., Iwasaki, N., Kawamura, M., Omori, Y., Rietzsch, H., Schulze, J., Schröder, H.E., Concannon, P.,
       Hanis, C.L., Spielman, R.S., Yamagata, K., Cox, N.J. & Bell, G.I. (1996) An approach for identifying
       simple sequences repeat DNA polymorphisms near cloned cDNAs and genes: linkage studies of the islet
       amyloid polypeptide/amylin and liver glycogen synthase genes and NIDDM. Diabetes 45:291-294.
53.    Hanis, C.L., Boerwinkle, E., Chakraborty, R., Ellsworth, D.L., Concannon, P., Stirling, B., Morrison,
       V.A., Wapelhorst, B., Spielman, R.S., Goglin-Ewens, K.J., Shephard, J.M., Williams, S.R., Risch, N.,
       Hinds, D., Iwasaki, N., Ogata, M., Omori, Y., Petzold, C., Rietzsch, H., Schröder, H.E., Schulze, J.,
       Cox, N.J., Menzel, S., Boriraj, V.V., Chen, X., Lim, L.R., Lindner, T., Mereu, L.E., Wang, Y.Q., Xiang,
       K.S., Yamagata, K., Yang, Y. & Bell, G.I. (1996) A genome-wide search for human non-insulin-
       dependent (Type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nature Genet
54.    Stoffel, M., Le Beau, M.M., Espinosa, III R., Bohlander, S.F., Le Paslier, D., Cohen, D., Xiang, K-S.,
       Cox, N.J., Fajans, S.S. & Bell, G.I. (1996) A yeast artificial chromosome-based map of the region of
       chromosome 20 containing the diabetes-susceptibility gene, MODY 1, and a myeloid leukemia related
       gene Proc Natl Acad Sci USA 93:3937-3941.
55.    Yamagata, K., Takeda, J., Menzel, S., Chen, X., Eng, S., Lim, L.R., Concannon, P., Hanis, C.L.,
       Spielman, R.S., Cox, N.J. & Bell, G.I. (1996) Searching for NIDDM susceptibility genes: studies of
       genes with triplet repeats expressed in skeletal muscle. Diabetologia 39:725-730.
56.    Iwasaki, N., Kawamura, M., Ohgawara, H., Karibe, S., Cox, N.J., Bell, G.I. & Omori, Y. (1996) Sib-pair
       analysis of Japanese NIDDM patients. J Japan Diab Soc 39:409-416 [in Japanese].
57.    Yamagata, K., Oda, N., Kaisaki, P.J., Menzel, S., Furuta, H., Vaxillaire, M., Southam, L., Cox, R.D.,
       Lathrop, M., Boriraj, V.V., Chen, X., Cox, N.J., Oda, Y., Yano, H., Le Beau, M.M., Yamada, S.,
       Nishigori, H., Takeda, J., Fajans, S.S., Hattersley, A.T., Iwasaki, N., Hansen, T., Pedersen, O., Polonsky,
       K.S., Turner, R.C., Velho, G., Chèvre, J.C., Froguel, P. & Bell, G.I. (1996) Mutations in the hepatocyte
       nuclear factor-1 gene in maturity-onset diabetes of the young (MODY3). Nature 384:455-458.
58.    Yamagata, K., Furuta, H., Oda, N., Kaisaki, P.J., Menzel, S., Cox, N.J., Fajans, S.S., Signorini, S.,
       Stoffel, M. & Bell, G.I. (1996) Mutations in the hepatocyte nuclear factor-4 gene in maturity-onset
       diabetes of the young (MODY1). Nature 384:458-460.
59.    Kong, A., Frigge, M., Bell, G.I., Lander, E., Daly, M. & Cox, N.J. (1997) Diabetes, dependence,
       asymptotics, significance, and selection. (Letter) Nature Genet 17:148.

Curriculum Vitae (cont.)
Nancy J. Cox
60.    Cook, E.H., Courchesne, R., Lord, C., Cox, N.J., Yan, S., Lincoln, A., Haas, R., Courchesne, E. &
       Leventhal, B.L. (1997) Evidence of linkage between the serotonin transporter and autistic disorder. Mol
       Psych 2:247-250.
61.    Ober, C., Cox, N.J., Lester, L.A., Peterson, R., Gidley, H., Pluzhnikov, A., Anderson, J., Solway, J.,
       Leff, A., Wolf, R., Wylam, M., Kurtz, B., Richardson, A. & Parry, R. (1997) A genome-wide search for
       asthma susceptibility loci in ethnically diverse populations: the collaborative study on the genetics of
       asthma (CSGA). Nature Genet 15:389-392.
62.    Bell, G.I., Cox, N.J., Lindner, T., Concannon, P., Spielman, R.S., Boerwinkle, E. & Hanis, C.L. (1997)
       Genetics of NIDDM in the Mexican Americans of Starr County, Texas: an update. Diabetes Reviews
63.    Boehnke, M. & Cox, N.J. (1997) Accurate inference of relationships in sib-pair linkage studies. Am J
       Hum Genet 61:423-429.
64.    Ober, C., Weitkamp, L.R., Cox, N.J., Dytch, H., Kostyu, D., Elias, S. (1997) HLA and mate choice in
       humans. Am J Hum Genet 61:497-504.
65.    Ambrose, N.G., Cox, N.J., Yairi, E. (1997) The genetic basis of persistence and recovery in stuttering. J
       Speech, Language, Hear Res 40:567-580.
66.    Kong, A. & Cox, N.J. (1997) Allele sharing models: LOD scores and accurate linkage tests. Am J Hum
       Genet 61:1179-1188.
67.    Lindner, T., Gragnoli, C., Schulze, J., Rietzsch, H., Petzold, C., Schröder, H.E., Cox, N.J. & Bell, G.I.
       (1997) The 31-cM region of chromosome 11 including the obesity gene Tubby and ATP-sensitive
       potassium channel genes, SUR1 and Kir6.2 does not contain a major susceptibility locus for NIDDM in
       127 non-Hispanic white affected sibships. Diabetes 46:1227-1229.
68.    Kong, A., Frigge, M., Bell, G.I., Lander, E., Daly, M. & Cox, N.J. (1997) Diabetes, dependence,
       asymptotics, significance and selection. Nature Genet 17:148.
69.    Ober, C. & Cox, N.J. (1998) Mapping genes for complex traits in founder populations. Clin Exper
       Allergy 28:101-105.
70.    Cook, E.H., Courchesne, R.Y., Cox, N.J., Lord, C., Pizzo, S., Gonen, D., Guter, S.J., Lincoln, A., Nix,
       K., Haas, R., Leventhal, B.L., Courchesne, E. (1998) Linkage disequilibrium mapping with 15q11-13
       markers in autistic disorder. Am J Hum Genet 62:1077-1083.
71.    Ober, C., Cox, N.J., Abney, M., Di Rienzo, A., Lander, E.S., Changyaleket, B., Gidley, H., Kurtz, B.,
       Lee, J., Nance, M., Petterson, A., Prescott, J., Richardson, A., Schlenker, E., Summerhill, E., Willadsen,
       S., Parry, R. & the Collaborative Study on the Genetics of Asthma. (1998) Genome-wide search for
       asthma susceptibility loci in a founder population. Hum Molec Genet 7:1393-1398.
72.    Concannon, P., Gogolin-Ewens, K.J., Hinds, D.A., Wapelhorst, B., Morrison, V.A., Stirling, B., Mitra,
       M., Farmer, J., Williams, S.R., Cox, N.J., Bell, G.I., Risch, N., & Spielman, R.S. (1998) A second
       generations screen of the human genome for susceptibility to insulin-dependent diabetes mellitus. Nature
       Genet 19:292-296.
73.    Cox, N.J., Frigge, M., Nicolae, D.L., Concannon, P., Hanis, C.L., Bell, G.I. & Kong, A. (1999) Loci on
       chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to type 2 diabetes. Nature Genet
74.    Pannain, S., Weiss, R.E., Jackson, C.E., Dian, D., Beck, J.C., Sheffield, V., Cox, N.J. & Refetoff, S.
       (1999) Two different mutations in the thyroid peroxidase gene of a large inbred Amish kindred: Power
       and limits of homozygosity mapping. J Clin Endocrinol Metab 84:1061-1071.
75.    Ober, C., Tsalenko, A., Willadsen, S.A., Newman, D.L., Daniel, R., Wu, X., Andal, J., Cox, N.J. (1999)
       Genome-wide screen for atopy susceptibility alleles in the Hutterites. Clin Exp Allergy Suppl 4:11-15.
76.    Hinokio, Y., Horikawa, Y., Furuta, H., Cox, N.J., Iwasaki, N., Honda, M., Ogata, M., Iwamoto, Y., & Bell,
       G.I. (2000) -Cell Transcription factors and diabetes: no evidence for diabetes-associated mutations in the

Curriculum Vitae (cont.)
Nancy J. Cox
       hepatocyte nuclear factor-3 gene (HNF3B) in Japanese patients with maturity-onset diabetes of the young.
       Diabetes 49:302-305.
77.    Ober, C., Leavitt, S.A., Tsalenko, A., Howard, T.D., Hoki, D.M., Daniel, R., Newman, D.L., Wu, X.,
       Parry, R., Lester, L.A., Solway, J., Blumenthal, M., King, R.A., Xu, J., Meyers, D.A., Bleecker, E.R. &
       Cox, N.J. (2000) Variation in the interleukin 4-receptor  gene confers susceptibility to asthma and
       atopy in ethnically diverse populations. Am J Hum Genet 66:517-526.
78.    Baier, L.J., Permana, P.A., Yang, X., Pratley, R.E., Hanson, R.L., Shen, G-Q., Mott, D., Knowler, W.C.,
       Cox, N.J., Horikawa, Y., Oda, N., Bell, G.I. & Bogardus, C. (2000) A calpain-10 gene polymorphism is
       associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest 106:R69-R73.
79.    Horikawa, Y., Oda, N., Cox, N.J., Li, X., Orho-Melander, M., Hara, M., Hinokio, Y., Lindner, T.H.,
       Mashima, H., Schwarz, P.E.H., del Bosque-Plata, L., Horikawa, Y., Oda, Y., Yoshiuchi, I., Colilla, S.,
       Polonsky, K.S., Shan, W., Concannon, P., Iwasaki, N., Schulze, J., Baier, L.J., Boguardus, C., Groop, L.,
       Boerwinkle, E., Hanis, C.L. & Bell, G.I. (2000) Genetic variation in the calpain 10 gene (CAPN10) is
       associated with type 2 diabetes mellitus. Nature Genet 126:163-175.
80.    Ober, C., Tsalenko, A., Parry, R. & Cox, N.J. (2000) A second-generations genomewide screen for
       asthma-susceptibility alleles in a founder population. Am J Hum Genet 67:1154-1162.
81.    Hara, M., Wang, X., Paz, V.P., Cox, N.J., Iwasaki, N., Ogata, M., Iwamoto, Y. & Bell, G.I. (2000) No
       diabetes-associated mutations in the coding region of the hepatocyte nuclear factor-4gamma gene
       (HNF4G) in Japanese patients with MODY. Diabetologia 43:1064-9.
82.    Horikawa, Y., Horikawa, Y., Cox, N.J., Iwasaki, N., Ogata, M., Iwamoto, Y., Schwitzgebel, V.,
       German, M.S. & Bell, G.I. (2000) Beta-cell transcription factors and diabetes: no evidence for diabetes-
       associated mutations in the gene encoding the basic helix-loop-helix transcription factor neurogenic
       differentiation 4 (NEUROD4) in Japanese patients with MODY. Diabetes. 49:1955-1957.
83.    Cox, N.J. (2001) Introduction: interactions in asthma. Genet Epidemiol 21:S264-265.
84.    Colilla, S., Tsalenko, A., Pluznikov, A. & Cox, N.J. (2001) Genome-wide approaches for identifying
       interacting susceptibility regions for asthma. Genet Epidemiol 21:S266-271.
85.    Evans, J.C., Frayling, T.M., Cassell, P.G., Saker, P.J., Hitman, G.A., Walker, M., Levy, J.C., O’Rahilly,
       S., Rao, P.V.S., Bennett, A.J., Jones, E.C., Menzel, S., Prestwich, P., Simecek, N., Wishart, M., Dhillon,
       R., Fletcher, C., Millward, A., Demaine, A., Wilkin, T., Horikawa, Y., Cox, N.J., Bell, G.I., Ellard, S.,
       McCarthy MI, Hattersley AT (2001) Studies of association between the gene for calpain-10 and type 2
       diabetes mellitus in the United Kingdom. Am J Hum Genet 69:544-552.
86.    Xu, J., Meyers, D.A., Ober, C., Blumenthal, M.N., Mellen, B., Barnes, K.C., King, R.A., Lester, L.A.,
       Howard, T.D., Solway, J., Langefeld, C.D., Beaty, T.H., Rich, S.S., Bleecker, E.R. & Cox, N.J. (2001)
       Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three
       U.S. populations: Collaborative study on the genetics of asthma. Am J Hum Genet 68:1437-1446.
87.    Colilla, S., Cox, N.J. & Ehrmann, D.A. (2001) Heritability of insulin secretion and insulin action in
       women with polycystic ovary syndrome and their first degree relatives. J Clin Endocrinol Metab
88.    del Bosque-Plata, L., Lin, J., Horikawa, Y., Schwarz, P.E., Cox, N.J., Iwasaki, N., Ogata, M., Iwamoto,
       Y., German, M.S. & Bell, G.I. (2001) Mutations in the coding region of the neurogenin 3 gene
       (NEUOROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects.
       Diabetes 50:694-696.
89.    Mathias, R.A., Freidhoff, L.R., Blumenthal, M.N., Meyers, D.A., Lester, L., King, R., Xu, J.F., Solway,
       J., Barnes, K.C., Pierce, J., Stine, O.C., Togias, A., Oetting, W., Marshik, P.L., Hetmanski, J.B., Huang,
       S.K., Ehrlich, E., Dunston, G.M., Malveaux, F., Banks-Schlegel, S., Cox, N.J., Bleecker, E., Ober, C.,
       Beaty, T.H. & Rich, S.S. (2001) Genome-wide linkage analyses of total serum IgE using variance
       components analysis in asthmatic families. Genet Epidemiol. 20:340-355.

Curriculum Vitae (cont.)
Nancy J. Cox
90.    Cox, N.J., Wapelhorst, B., Morrison, V.A., Johnson, L., Pinchuk, L., Spielman, R.S., Todd, J.A.,
       Concannon, P. (2001) Seven regions of the genome show evidence of linkage to type 1 diabetes in a
       consensus analysis of 767 multiplex families. Am J Hum Genet 69:820-830
91.    Sreenan, S.K., Zhou, Y-P., Otani, K., Hansen, P.A., Currie, K.P.M., Pan, C-Y., Lee, J-P., Ostrega, D.M.,
       Pugh, W., Horikawa, Y., Cox, N.J., Hanis, C.L., Burant, C.F., Fox, A.P., Bell, G.I. & Polonsky, K.S.
       (2001) Calpains play a role in insulin secretion and action. Diabetes 50:2013-2020.
92.    Cox, N.J. (2001) Challenges in identifying genetic variation affecting susceptibility to type 2 diabetes:
       Examples from studies of the calpain-10 gene. Hum Molec Genet 10:2301-2305.
93.    Newman, D.L., Abney, M., McPeek, M.S., Ober, C. & Cox, N.J. (2001) The importance of genealogy in
       determining genetic associations with complex traits. Am J Hum Genet 69:1146-1148.
94.    Cox, N.J. (2001) Computational issues in mapping variation affecting susceptibility to complex
       disorders: the chicken and the egg. Theor Popul Biol 60:221-25.
95.    Nicolae, D.L. & Cox, N.J. (2002) MERLIN...and the geneticist's stone? Nat Genet 30:3-4. Invited
96.    Lynn, S., Evans, J.C., White, C., Frayling, T.M., Hattersley, A.T., Turnbull, D.M., Horikawa, Y., Cox,
       N.J., Bell, G.I. & Walker, M. (2002) Variation in the calpain-10 gene affects blood glucose levels in the
       British population. Diabetes 51:247-250.
97.    Sun, L., Cox, N.J. & McPeek, M.S. (2002) A statistical method for identification of polymorphisms that
       explain a linkage result. Am J Hum Genet. 70:399-411.
98.    Elbein, S.C., Chu, W., Ren, Q., Hemphill, C., Schay, J., Cox, N.J., Hanis, C.L. & Hasstedt, S.J. (2002)
       Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians. J Clin Endocrinol Metab
99.    Hara, M., Alcoser, S.Y., Qaadir, A., Beiswenger, K.K., Cox, N.J. & Ehrmann, D.A. (2002) Insulin
       resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymorphism in
       the PPARgamma gene. J Clin Endocrinol Metab 87:772-775.
100.   Fullerton, S.M., Bartoszewicz, A., Ybazeta, G., Horikawa, Y., Bell, G.I., Kidd, K.K., Cox, N.J.,
       Hudson, R.R. & Di Rienzo, A. (2002) Geographic and haplotype structure of candidate type 2 diabetes
       susceptibility variants at the calpain-10 locus. Am J Hum Genet 70:1096-1106.
101.   Ehrmann, D. A., Schwartz, P. E. H., Hara, M., Tang, X., Horikawa, Y., Imperial, J., Bell, G. I., Cox, N.
       J. (2002) Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome. J.
       Clin. Endocrinol. Metab. 87:1669-1673.
102.   Haddad, L., Evans, J.C., Gharani, N., Robertson, C., Rush, K., Wiltshire, S., Frayling, T.M., Wilkin, T.J.,
       Demaine, A., Millward, A., Hattersley, A.T., Conway, G., Cox, N.J., Bell, G.I., Franks, S. & McCarthy, M.I.
       (2002) Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome. J
       Clin Endocrinol Metab 87:2606-2610.
103.   Cox, N.J. (2002) Calpain 10 and genetics of type 2 diabetes. Curr Diab Rep. 2:186-90.
104.   Pritchard, J.K. & Cox, N.J. (2002) The allelic architecture of human disease genes: common disease—
       common variant—or not? Human Molecular Genetics 11:2417-2423.
105.   Rasmussen, S.K., Urhammer, S.A., Berglund, L., Jensen, J.N., Hansen, L., Echwald, S.M., Borch-Johnsen,
       K., Horikawa, Y., Mashima, H., Lithell, H., Cox, N.J., Hansen, T., Bell, G.I., Pederson, O. (2002) Variants
       within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin
       resistance, and impaired acute insulin secretion among Scandinavian Caucasians. Diabetes 51(12):3561-
106.   Ehrmann, D.A., Tang, X., Yoshiuchi, I., Cox, N.J., Bell, G.I. (2002) Relationship of insulin receptor
       substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome. J Clin Endocrinol Metab

Curriculum Vitae (cont.)
Nancy J. Cox
107.   Hanna, G.L., Vennstra-VanderWeele, J., Cox, N.J., Boehnke, M., Himle, J.A., Curtis, G.C., Leventhal, B.L.,
       Cook, E.H. Jr. (2002) Genome-wide linkage analysis of families with obsessive-compulsive disorder
       ascertained through pediatric probans. Am J Med Genet 114(5):541-52.
108.   Colilla, S., Nicolae, D., Pluzhnikov, A., Blumethal, M.N., Beaty, T.H., Bleecker, E.R., Lange, E.M., Rich,
       S.S., Meyers, D.A., Ober, C., Cox, N.J., and the CSGA (2003) Evidence for gene-environment interactions
       in a linkage study of asthma and smoking exposure. J Allergy Clin Immunol 111(4):840-846.
109.   Zhou, Y.P., Sreenan, S., Pan, C.Y., Currie, K.P., Bindokas, V.P., Horikawa, Y., Lee, J.P., Ostrega, D.,
       Ahmed, N., Balswin, A.C., Cox, N.J., Fox, A.P., Miller, R.J., Bell, G.I., Polonsky, K.S. (2003) A 48-hour
       exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis
       of insulin. Metabolism 52(5):528-534.
110.   Canizales-Quinteros, S., Aguilar-Salinas, C.A., Reyes-Rodriguez, E., Riba, L., Rodriguez-Torres, M.,
       Ramirez-Jimenez, S., Huertas-Vazquez, A., Fragoso-Onitveros, V., Zentell-Dehesa, A. Ventura-Gallegos, J.
       L., Vega-Hernandez, G., Lopez-Estrada, A., Auron-Gomex-Perez, F., Rull, J., Cox, N.J., Bell, G.I., Tusie-
       Luna, M.T. (2003) Locus on chromosome 6p linked to elevated HDL cholesterol serum levels and to
       protection against premature atherosclerosis in a kindred with familial hypercholesterolemia. Circ Res
111.   Tsalenko A., Ben-Dor A., Cox, N.J., Yakhini, Z. (2003) Methods for analysis and visualization of SNP
       genotype data for complex diseases. Pac Symp Biocomput. 548-61.
112.   Iwasaki, N., Cox, N.J., Wang, Y.Q., Schwartz, P.E., Bell, G.I., Honda, M., Imura, M., Ogata, M., Saito, M.,
       Kamatani, N., Iwamoto, Y. (2003) Mapping genes influencing type 2 diabetes risk and BMI in Japanese
       subjects. Diabetes 52(1):209-13.
113.   Naoumova, R.P., Bonney, S.A., Eichenbaum-Voline, S., Patel, H.N., Jones, B., Jones, E.L., Amey, J.,
       Solilla, S., Neuwirth, C.K., Allotey, R., Seed, M., Betteridge, D.J., Galton, D.J., Cox, N.J., Bell, G.I., Scott,
       J., Shoulders, C.C. (2003) Confirmed Locus on chromosome 11p and candidate loci on 6q and 8p for the
       triglyceride and cholesterol traits of combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 23 (11):2070-
114.   Ng, M.C., So, W.Y., Cox, N.J., Lam, V.K., Cockram, C.S., Critchley, J.A., Bell, G.I., Chan, J.C. (2004)
       Genome-wide Scan for Type 2 Diabetes Loci in Hong Kong Chinese and Confirmation of a Susceptibility
       Locus on Chromosome 1q21-q25. Diabetes. 53 (6):1609-13.
115.   Cox, N.J., Hayes, M.G., Roe, C.A., Tsuchiya, T., Bell, G.I. (2004) Linkage of calpain 10 to type 2 diabetes:
       the biological rationale. Diabetes. 53 Suppl 1:S19-25. Review.
116.   del Bosque-Plata, L., Aguilar-Salinas, C.A., Tusie-Luna, M.T., Ramirez-Jimenez, S., Rodriguez-Torres, M.,
       Auron-Gomez, M., Ramirez, E., Velasco-Perez, M.L., Ramirez-Silva, A., Gomez-Perez, F., Hanis, C.L.,
       Tsuchiya, T., Yoshiuchi, I., Cox, N.J., Bell, G.I. (2004) Association of the calpain-10 gene with type 2
       diabetes mellitus in a Mexican population. Mol Genet Metab 81 (2):122-6.
117.   Chen, Y.S., Akula, N., Detera-Wadleigh, S.D., Schulze, T.G., Thomas, J., Potash, J.B., DePaulo, J.R.,
       McInnis, M.G., Cox, N.J., McMahon, F.J. (2004) Findings in an independent sample support an association
       between bipolar affective disorder and the G72/G30 locus on chromosome 13q33. Mol Psychiatry. 9 (1):87-
118.   Blumenthal, M.N., Langefeld, C.D., Beaty, T.H., Bleecker, E.R., Ober, C., Lester, L., Lange, E., Barnes,
       K.C., Wolf, R., King, R.A., Solway, J., Oetting, W., Meyers, D.A., Rich, S.S. (2004) A genome-wide search
       for allergic response (atopy) genes in three ethnic groups: Collaborative Study on the Genetics of Asthma.
       Hum Genet. 114(2):157-64.
119.   Blumenthal, M.N., Ober, C., Beaty, T.H., Bleecker, E.R., Langefeld, C.D., King, R.A., Lester, L., Cox, N.J.,
       Barnes, K., Togias, A., Mathias, R., Meyers, D.A., Oetting, W., Rich, S.S. for the CSGA (2004) Genome
       scan for loci linked to mite sensitivity: the Collaborative Study on the Genetics of Asthma (CSGA). Genes
       and Immunity (2004), 1-6.

Curriculum Vitae (cont.)
Nancy J. Cox
120. Ng, M.C., So, W.Y., Lam, V.K., Cockram, C.S., Bell, G.I., Cox, N.J., Chan, J.C. (2004) Genome-wide
     scan for metabolic syndrome and related quantitative traits in Hong Kong Chinese and confirmation of a
     susceptibility locus on chromosome 1q21-q25. Diabetes 53(10):2676-83.
121. Schulze, T.G., Buervenich, S., Badner, J.A., Steele, C.J., Detera-Wadleigh, S.D., Dick, D., Foroud, T.,
     Cox, N.J., MacKinnon, D.F., Potash, J.B., Berrettini, W.H., Byerley, W., Coryell, W., DePaulo, J.R. Jr,
     Gershon, E.S., Kelsoe, J.R., McInnis, M.G., Murphy, D.L., Reich, T., Scheftner, W., Nurnberger, J.I. Jr,
     McMahon, F.J. (2004) Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar
     affective disorder in the national institute of mental health genetics initiative pedigrees. Biol Psychiatry
122. Cox N.J. (2004) Human genetics: an expression of interest. Nature 430(7001):733-4. Invited
123. Nicolae, D., Cox, N.J., Lester, L.A., Schneider, D., Tan, Z., Billstrand, C., Kuldanek, S., Donfack, J.,
     Kogut, P., Patel, N.M., Goodenbour, J., Howard, T., Wolf, R., Koppelman, G.H., White, S.R., Parry, R.,
     Postma, D.S., Meyers, D., Bleecker, E.R., Hunt, J.S., Solway, J., Ober, C. (2005) Fine Mapping and
     Positional Candidate Studies Identify HLA-G as an Asthma Susceptibility Gene on Chromosome 6p21.
     Am J Hum Genet. 76(2):349-57.
124. Iwasaki, N., Horikawa, Y., Tsuchiya, T., Kitamura, Y., Nakamura, T., Tanizawa, Y., Oka, Y., Hara, K.,
     Kadowaki, T., Awata, T., Honda, M., Yamashita, K., Oda, N., Yu, L., Yamada, N., Ogata, M.,
     Kamatani, N., Iwamoto, Y., Del Bosque-Plata, L., Hayes, M.G., Cox, N.J., Bell, G.I. (2005) Genetic
     variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population. J
     Hum Genet 50(2):92-8.
125. Riaz, N., Steinberg, S., Ahmad, J., Pluzhnikov, A., Riazuddin, S., Cox, N.J., Drayna, D. (2005)
     Genomewide significant linkage to stuttering on chromosome 12. Am J Hum Genet 76(4):647-51.
126. Clark, V.J., Cox, N.J., Hammond, M., Hanis, C.L., Di Rienzo, A. (2005) Haplotype structure and
     phylogenetic shadowing of a hypervariable region in the CAPN10 gene. Hum Genet 117:258-66.
127. Wittke J.K., Pluzhnikov, A., Cox, N.J. (2005) Rational inferences about departures from Hardy-
     Weinberg equilibrium. Am J Hum Genet 76:967-86.
128. Ng, M.C.Y., Miyake, K., So, W.Y., Poon, E.W.M, Lam, V.K.L., Li, J.K.Y., Cox, N.J., Bell, G.I., Chan,
     J.C.N. (2005) The linkage and association of the gene encoding upstream stimulatory factor 1 with type
     2 diabetes and metabolic syndrome in the Chinese population. Diabetologia 48:2018-24.
129. Hayes, M.G., del Bosque-Plata, L., Tsuchiya, T., Hanis, C.L., Bell, G.I., Cox, N.J. (2005) Patterns of
     linkage disequilibrium in the type 2 diabetes gene calpain-10. Diabetes 54:3573-6.
130. Suresh, R., Ambrose, N., Roe, C., Pluzhnikov, A., Wittke-Thompson, J.K., Ng, M.C., Wu, X., Cook,
     E.H., Lundstrom, C., Garsten, M., Ezrati, R., Yairi, E., Cox, N.J. (2006) New complexities in the
     genetics of stuttering: significant sex-specific linkage signals. Am J Hum Gene 78:554-63.
131. Suarez, B.K., Duan, J., Sanders, A.R., Hinrichs, A.L., Jin, C.H., Hou, C., Buccola, N.G., Hale, N.,
     Weilbaecher, A.N., Nertney, D.A., Olincy, A., Green, S., Schaffer, A.W., Smith, C.J., Hannah, D.E.,
     Rice, J.P., Cox, N.J., Martinez, M., Mowry, B.J., Amin, F., Silverman, J.M., Black, D.W., Byerley,
     W.F., Crowe, R.R., Freedman, R., Cloninger, C.R., Levinson, D.F., Gejman, P.V. (2006) Genomewide
     linkage scan of 409 European-Ancestry and African American families with schizophrenia: Suggestive
     evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample. Am J Hum Genet
132. Dickel, D.E., Veenstra-Vanderweele, J., Cox, N.J., Wu, X., Fischer, D.J., Van Etten-Lee, M., Himle,
     J.A., Leventhal, B.L., Cook, E.H. Jr, Hanna, G.L. (2006) Association testing of the positional and
     functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder. Arch Gen
     Psychiat 63:776-85.
133. Nicolae, D.L., Wu, X., Miyake, K., Cox, N.J. (2006) GEL: A novel genotype calling algorithm using

Curriculum Vitae (cont.)
Nancy J. Cox
       empirical likelihood. Bioinformatics 22:1942-7.
134.   Pihlajamaki, J., Salmenniemi, U., Vanttinen, M., Ruotsalainen, E., Kuusisto, J., Vauhkonen, I.,
       Kainulainen, S., Ng, M.C., Cox, N.J., Bell, G.I., Laakso, M. (2006) Common polymorphisms of calpain-
       10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes. Diabetologia
135.   Nicolae, D.L., Wen, X., Voight, B.F., Cox, N.J. (2006) Coverage and characteristics of the Affymetrix
       GeneChip Human Mapping 100K SNP set. PLoS Genet 2:e67.
136    Yokoi, N., Kanamori, M., Horikawa, Y., Takeda, J., Sanke, T., Furuta, H., Nanjo, K., Mori, H., Kasuga,
       M., Hara, K., Kadowaki, T., Tanizawa, Y., Oka, Y., Iwami, Y., Ohgawara, H., Yamada, Y., Seino, Y.,
       Yano, H., Cox, N.J., Seino, S. (2006) Association studies of variants in the genes involved in pancreatic
       (beta)-cell function in type 2 diabetes in Japanese. Diabetes 55:2379-86.
137.   Tsuchiya, T., Schwarz, P.E., Bosque-Plata, L.D., Hayes, M.G., Dina, C., Froguel, P., Towers, G.W.,
       Fischer, S., Temelkova-Kurktschiev, T., Rietzsch, H., Graessler, J., Vcelak, J., Palyzova, D., Selisko, T.,
       Bendlova, B., Schulze, J., Julius, U., Hanefeld, M., Weedon, M.N., Evans, J.C., Frayling, T.M.,
       Hattersley, A.T., Orho-Melander, M., Groop, L., Malecki, M.T., Hansen, T., Pedersen, O., Fingerlin,
       T.E., Boehnke, M., Hanis, C.L., Cox, N.J., Bell, G.I. (2006) Association of the calpain-10 gene with
       type 2 diabetes in Europeans: results of pooled and meta-analyses. Mol Genet Metab 89:174-84.
138.   Kurz, T., Hoffjan, S., Hayes, M.G., Schneider, D., Nicolae, R., Heinzmann, A., Jerkic, S.P., Parry, R.,
       Cox, N.J., Deichmann, K.A., Ober, C. (2006) Fine mapping and positional candidate studies on
       chromosome 5p13 identify multiple asthma susceptibility loci. J Allergy Clin Immunol 118:396-402.
139.   Bourgain, C., Genin, E., Cox, N., Clerget-Darpoux, F. (2006) Are genome-wide association studies all
       that we need to dissect the genetic component of complex human diseases? Eur J Hum Genet 15(3):260-
140.   Huang, R.S., Duan, S., Bleibel, W.K., Kistner, E.O., Zhang, W., Clark, T.A., Chen, T.X., Schweitzer,
       A.C., Blume, J.E., Cox, N.J., Dolan, M.E. (2007) A genome-wide approach to identify genetic variants
       that contribute to etoposide-induced cytotoxicity. Proc Natl Acad Sci USA 104(23):9758-63.
141.   Zhang, W., Bleibel, W.K., Roe, C.A., Cox, N.J., Dolan, M.E. (2007) Gender-specific differences in
       expression in human lymphoblastoid cell lines. Pharmacogenet Genomics 17(6):447-50.
142.   Hoffmann, K., Mattheisen, M., Dahm, S., Nürnberg, P., Roe, C., Johnson, J., Cox, N.J., Wichmann,
       H.E.., Wienker, T.F., Schulze, J., Schwarz, P.E., Lindner, T.H. (2007) A German genome-wide linkage
       scan for type 2 diabetes supports the existence of a metabolic syndrome locus on chromosome 1p36.13
       and a type 2 diabetes locus on chromosome 16p12.2. Diabetologia 50(7):1418-22.
143.   Wittke-Thompson, J.K., Ambrose, N., Yairi, E., Roe, C., Cook, E.H., Ober, C., Cox, N.J. (2007)
       Genetic studies of stuttering in a founder population. J Fluency Disord 32(1):33-50.
144.   Carter, K.W., Pluzhnikov, A., Timms, A.E., Miceli-Richard, C., Bourgain, C., Wordsworth, B.P., Jean-
       Pierre, H., Cox, N.J., Palmer, L.J., Breban, M., Reveille, J.D., Brown, M.A. (2007) Combined analysis
       of three whole genome linkage scans for Ankylosing Spondylitis. Rheumatology 46(5):763-71.
145    Hanna, G.L., Veenstra-Vanderweele, J., Cox, N.J., Etten, M.V., Fischer, D.J., Himle, J.A., Bivens, N.C.,
       Wu, X., Roe, C.A., Hennessy, K.A., Dickel, D.E., Leventhal, B.L., Cook, Jr. E.H. (2007) Evidence for a
       susceptibility locus on chromosome 10p15 in early-onset obsessive-compulsive disorder. Biol Psych
146.   Liu, W., Wu, X., Zhang, W., Montenegro, R.C., Fackenthal, D.L., Spitz, J.A., Huff, L.M., Innocenti, F.,
       Das, S., Cook, E.H., Jr, Cox, N.J., Bates, S.E., Ratain, M.J. (2007) Relationship of EGFR mutations,
       expression, amplification, and polymorphisms to epidermal growth factor receptor inhibitors in the
       NCI60 cell lines. Clin Cancer Res 13:6788-95.
147.   Maitland, M.L., Ratain, M.J., Cox, N.J. (2007) Interpreting P values in pharmacogenetics studies: A call
       for process and perspective. J Clin Oncol 25(29):4513-5.

Curriculum Vitae (cont.)
Nancy J. Cox
148.   Støy, J., Edghill, E.L., Flanagan, S.E., Ye, H., Paz, V.P., Pluzhnikov, A., Below, J.E., Hayes, M.G., Cox,
       N.J., Lipkind, G.M., Lipton, R.B., Greeley, S.A., Patch, A.M., Ellard, S., Steiner, D.F., Hattersley, A.T.,
       Philipson, L.H., Bell, G.I.; Neonatal Diabetes International Collaborative Group (2007) Insulin gene
       mutations as a cause of permanent neonatal diabetes. Proc Natl Acad Sci USA 104(38):15040-4.
149.   Hayes, M.G., Pluzhnikov, A., Miyake, K., Sun, Y., Ng, M.C., Roe, C.A., Below, J.E., Nicolae, R.I.,
       Konkashbaev, A., Bell, G.I., Cox, N.J., Hanis, C.L. (2007) Identification of type 2 diabetes genes in
       Mexican Americans through genome-wide association studies. Diabetes 56(12):3033-44.
150.   Potash, J.B., Buervenich, S., Cox, N.J., Zandi, P.P., Akula, N., Steele, J., Rathe, J.A., Avramopoulos,
       D., Detera-Wadleigh, S.D., Gershon, E.S., DePaulo, J.R., Jr, Feinberg, A.P., McMahon, F.J.; NIMH
       Genetics Initiative Bipolar Disorder Consortium (2008) Gene-based SNP mapping of a psychotic bipolar
       affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1. Am J Med Genet B
       Neuropsychiatr Genet 147(1):59-67.

Non-peer reviewed reports:

1.     Xiang, K., Cox, N.J., Hallewell, R.A., and Bell, G.I. (1987) Multiple Taq I RFLPs at the human
       manganese superoxide dismutase locus on chromosome 6. Nucl Acids Res 15:7654.
2.     Xiang, K., Cox, N.J., Karam, J.H., and Bell, G.I. (1987) Bgl II RFLP at the human erythrocyte/HepG2-
       type glucose transporter (GLUT) locus on chromosome 1. Nucl Acids Res 15:9101.
3.     Xiang, K., Cox, N.J., and Bell, G.I. (1988) Apa I and Sst I RFLPs at the insulin-like growth factor II
       (IGF2) locus on chromosome 11. Nucl Acids Res 16:3599.
4.     Cox, N.J., Spielman, R.S., Kahn, C.R., Mueller-Weiland, D., Kriauciuinas, K.M., and Taub, R. (1988)
       Four RFLPs of the insulin receptor gene: Pst I, Kpn I, Rsa I (2 RFLPs). Nucl Acids Res 16:8204.
5.     Cox, N.J., Spielman, R.S., Kahn, C.R., Muller-Weiland, D., Kriauciuinas, K.M., and Taub, R. (1989)
       Four RFLPs of the insulin receptor gene: Pst I, Kpn I, Rsa I (2 RFLPs). Nucl Acids Res 17:820.

 Book Chapters
1. Bell, G.I., Cockburn, B.N., Cox, N.J., Daniel, J.C., del Bosque Plata, L., Fajans, S.S., Gragnoli, C., Hara,
    M., Horikawa, Y., Horikawa, Y., Iwamoto, Y., Iwasaki, N., Li, X., Mashima, H., Njølstad, P.R., Ogata, M.,
    Patterson, B., Paz, V.P., Polonsky, K.S., Qaadir, A., So, W.Y., Wang, X., & Ye, H. (1999) Maturity-onset
    diabetes of the young - a model for genetic studies of diabetes mellitus. In A Common Disease-Genetic and
    Pathogenetic Aspects of Multifactorial Diseases Edited by Imura, H., Kasuga, M., and Nakao, K., Elsevier
    Science pp 107-120.
2. Cox, N.J. (2002) Approaches to identifying genetic variation for complex phenotypes. In Genome Science-
   Towards a New Paradigm? Edited by H. Yoshikawa, N. Ogasawara, N. Satoh; Elsevier Science BV,
   Amsterdam, The Netherlands, pp. 241-250.

Invited Speaker – Meetings, Seminars & Symposia
09/98 Plenary Lecture, 1998 International Genetic Epidemiology Society Meeting, Arcachon, France
11/98 Invited Speaker, New Horizon in the Pathogenesis of Diabetes Mellitus, Kyoto, Japan
04/00 Invited Speaker, Diabetes Conference, Denmark
06/00 Invited Speaker, German Diabetes Meeting, Aachen, Germany
07/00 Invited Speaker, Burroughs Wellcome Trust, Cambridge, England
07/00 Invited Seminar, Steno Diabetes Center, Copenhagen, Denmark
09/00 Visiting Scholar, Japanese Diabetes Society, Tokyo, Japan
09/00 Invited Seminar, Kyoto, Japan

Curriculum Vitae (cont.)
Nancy J. Cox
09/00 Invited Seminar, Kobe, Japan
09/00 Invited Seminar, Miyobashi, Japan
11/00 Invited Speaker, Genetics of Complex Disorders, Telethon Italy, Rimini, Italy
07/01 Invited Speaker, Australian Human Genetics Meetings, Cairns, Australia
08/01 Plenary Speaker, International Congress of Schizophrenia Whistler, British Columbia
09/01 Invited Speaker, European Association of Diabetes, Glasgow, Scotland
09/01 Invited Seminar, Section of Endocrinology, Exeter University, Exeter, England
12/01 Invited Speaker, Diabetes Mellitus Meetings, Erice, Italy
04/02 Invited Speaker, Anniversary Symposium, Wurzburg, Germany
04/02 Invited Seminar, Department of Statistical Genetics, Bonn, Germany
05/02 Invited Speaker, Asian Pacific Diabetes Congress, Beijing, China
06/02 Invited Speaker, Uehara Symposium, Tokyo, Japan
09/02 Invited Speaker, Diabetes and Cardiovascular Risk Factors-East Meets West Symposium, Hong Kong, China
10/02 Invited Speaker, SNP Meeting, Reykjavik, Iceland
10/02 Invited Seminar, Shanghai, China
02/03 Invited Speaker, Genomics Bonn, Bonn, Germany
03/03 Invited Speaker, Servier-IGES Symposia, Cap St. Jean Ferrat, France
04/03 Invited Speaker, Ankylosing Spondilitis Consortium Meeting, Oxford, England
08/03 Invited Speaker, IDF-GD Congress, Lille, France
05/04 Invited Speaker, European Consortium for Type 1 Diabetes, Barcelona, Spain
11/04 Invited Speaker, Samsung International Symposium, Seoul, South Korea
09/05 Invited Speaker, SNP2005 Meeting, Leicestershire, England
09/06 Invited Speaker, 1st Nordic Meeting on Genetics and Pathogenesis of Immunological Diseases, Helsinki,
12/06 Invited Speaker, University of Toronto, Toronto, CA
09/07 Organizer and speaker, Human Genome Variation meeting, Barcelona, Spain
09/07 Invited Speaker, Pharmacogenetics Meeting, Costa Rica
02/08 Invited Speaker, Phamacogenetics Symposium, Tokyo, Japan
04/08 Invited Speaker, Statistical Genetics for Complex Diseases Symposium, Malmo, Sweden

12/97 Invited Speaker, Genetic Architecture of Complex Disorders, Baltimore, MD
06/98 Invited Speaker, American Diabetes Association Meetings, Chicago, IL
07/98 Invited Seminar, Department of Human Genetics, The University of Utah, Salt Lake City, UT
10/98 Invited Speaker, 100th Anniversary of the Joslin Diabetes Center, Boston, MA
03/99 Invited Speaker, NIH Workshop Gene-Environment Interaction, Research Triangle Park, North Carolina
04/99 Invited Seminar, Department of Human Genetics, University of Michigan, Ann Arbor, Michigan
10/99 Invited Seminar, Department of Human Genetics, Yale University, New Haven, CT
10/99 Plenary Speaker, World Psychiatric Genetic Congress, Monterey, CA
11/99 Invited Seminar, Oregon Health Sciences Center, Portland, OR
12/99 Invited Seminar, Southwest Foundation for Biomedical Research, San Antonio, TX
04/00 Invited Seminar, Department of Human Genetics, The University Pittsburgh, Pittsburgh, PA
06/00 Invited Speaker, American Diabetes Association Meetings, San Diego, CA
09/00 Invited Speaker, Newton Morton Celebration, St. Louis, MO
11/00 Invited Seminar, Department of Psychiatry, The University of Virginia, Charlotte, Virginia
01/01 Invited Speaker, NIH Conference Diabetes and Depression, Bethesda, MD

Curriculum Vitae (cont.)
Nancy J. Cox
06/01 Invited Speaker, Endocrine Society Meetings, Denver, CO
06/01 Invited Seminar, Department of Psychiatry, University of Colorado, Denver, CO
09/01 Invited Speaker, Hypertension Meetings, Chicago, IL
11/01 Invited Seminar, Department of Human Genetics, UCLA, Los Angeles, CA
04/02 Invited Speaker, NHLBI Consortium Studies, Bethesda, MD
06/02 Invited Seminar, Division of Biostatistical Genetics, The University of Alabama, Birmingham, AL
11/02 Invited Seminar, Biology Department, The University of Miami, Oxford, OH
12/02 Invited Seminar, Biostatistics Department, The University of Wisconsin, Wisconsin
04/03 Invited Speaker, NIH celebration of the 50th anniversary of Watson & Crick’s discovery of the structure of the
     DNA double helix—―From Double Helix to Human Sequence and Beyond!‖, Bethesda, MD
08/03 Invited Speaker, Gordon Conferences on Human Genetics and Genomics, Colby College-Waterville, Maine
09/03 Invited Speaker, Genome Technology Branch, Bethesda, MD
02/04 Invited Seminar, Dept. of Biology, Oberlin College, Oberlin, OH
03/04 Invited Seminar, University of Arizona, Tuscon, AZ
04/04 Invited Seminar, Dept. of Human Genetics, University of Michigan, Ann Arbor, MI
06/04 Invited Speaker, International Applied Mathematics Society, Nashville, TN
10/04 Invited Speaker, Genetics of Type 2 Diabetes, American Society of Human Genetics Meetings, Toronto, CN
10/04 Invited Speaker, Gene x environment Interaction, American Society of Human Genetics Meetings, Toronto
11/04 Invited Seminar, Dept. of Human Genetics, Emory University, Atlanta, GA
02/05 Invited Speaker, Genetic Epidemiology of Common Diseases: Integrating Genetics, Biology and Medicine,
       The 2005 meeting of the Genetic Epidemiology Research Institute (GERI), San Diego, CA
03/05 Invited Speaker, State of the Science in Stuttering Workshop, Washington, D.C.
05/05 Invited Seminar, Wake Forest University
06/05 Invited Speaker, American Diabetes Association Meetings, San Diego, CA
09/05 Invited Scholar, Mayo Clinic, Rochester, Minnesota
10/05 Invited Speaker, World Congress on Genetics of Schizophrenia, Boston, MA
11/05 Invited Speaker, NHGRI retreat, Gettysburg, PA
11/05 Invited Speaker, Grand Rounds, Endocrine Section, Northwestern University, Chicago, IL
 3/06 Invited Speaker, APPA, New York, NY
 4/06 Invited Speaker, North Carolina State University, Raleigh Durham, NC
 9/06 Invited Speaker, NIMH retreat, Gettysburg, PA
10/06 Invited Speaker, Yale Symposium on Genome-wide Association Studies, New Haven, CT
11/06 Invited Speaker, GAIN meetings, Washington, DC
12/06 Invited Speaker, NCI Wednesday Afternoon Lecture Series
02/07 Invited Speaker, Mesothelioma Pathogenesis meeting, Honolulu, Hawaii
02/07 Invited Speaker, National Association of Allergy meetings, San Diego, CA
03/07 Invited Seminar, University of California San Francisco, San Francisco, Ca
04/07 Invited Seminar, Case Western Reserve University, Cleveland, OH
05/07 Invited Speaker, Carnegie Mellon Symposium on Computational Biology, Pittsburgh, PA
06/07 Invited Speaker, GEI Symposium, Boston, MA
10/07 Invited Speaker, Harvard Genomics Conference, Boston, MA
11/07 Invited Speaker, American Society of Nephrology Meetings, San Francisco, CA
11/07 Invited Seminar, University of Texas Health Sciences Center, Houston, TX
1/08 Invited Speaker, Statistical Genetics in Pharmacogenetics, Memphis, TN
3/08 Invited Seminar, Emory University, Atlanta, GA

Curriculum Vitae (cont.)
Nancy J. Cox

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