Introduction to physical organic chemistry by langstonwalker

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									Introduction to physical
organic chemistry
Thursday 17 September 2009
Syngenta, Jealott’s Hill, UK




Organised by SCI’s Young Chemists’ Panel
of SCI’s Fine Chemicals Group
            09:30      Registration and refreshments
programme
            09:50      General introduction: Physical organic chemistry
                       (POC) for synthetic organic chemists (SOC) - Peter Shapland
            10:05      Introduction to kinetics I - David Fox
            10:50      Introduction to kinetics II - Niek Buurma
            11:35      Refreshment break
            11:55      Techniques for data collection - Peter Shapland & Niek Buurma
            12:55      Reaction design for pseudo 1st order kinetics - Peter Shapland
            13:40      Lunch
            14:25      What does it mean? - Niek Buurma
            15:10      Taking POC for SOC further - David Fox
            16:10      Refreshments
            16:30      Case study - Professor J. Harrity, University of Sheffield

            17:30      Close


tutor biographies
Dr Niek Buurma, Cardiff University
M.Sc. (1997) and Ph.D. (2003) in physical organic chemistry cum laude under the supervi-
sion of Prof. J.B.F.N. Engberts (University of Groningen, The Netherlands) working on kinetic
studies of intermolecular interactions in aqueous solutions. Niek then moved to the University
of Sheffield where he worked as a Postdoctoral Research Associate under the supervision of
Prof. C.A. Hunter and Dr. I. Haq on intermolecular interactions in solution. In 2006, he took
up a lectureship in the Physical Organic Chemistry Centre in the School of Chemistry, Cardiff
University.

Dr David Fox, Warwick University
B.A. in Chemistry, Wadham College, Oxford (1994). D.Phil. with Prof. S. Davies, Dyson Perrins,
Oxford (asymmetric synthesis). David completed his Post-doctoral research at The Depart-
ment of Chemistry, Cambridge, collaborating with Dr S. Warren (Chemistry), Dr D.J. Grainger
(Medicine) and Dr D.R. Spring (Chemistry) on asymmetric synthesis and medicinal chemistry.
From 2006 David has been an EPSRC Advanced Research Fellow and University Lecturer,
Department of Chemistry, Warwick. Reseach interests include medicinal chemistry, synthetic
methodology and reaction mechanism.

Dr Peter Shapland, GlaxoSmithKline
B.Sc.(1996) and Ph.D. (2000) at University of Manchester. Ph.D. with Prof. J. Thomas working
towards total synthesis of Phomactin A. Peter enjoyed a brief spell at Roche working in the
PR&D department and then moved to University of Michigan with Prof. Ed Vedejs as a Post-
doctoral Research Associate working on hydroborations utilising Lewis-base borane adducts.
He joined the Chemical Development team at GSK in 2001 working on the development of
medicines for treatment of asthma, COPD, diabetes, atheroclerosis.
                     This meeting will be of        Synthetic chemists need to have a mechanistic
synopsis
                     interest to both academic      understanding of the reactions they conduct to allow
                     and industrial chemists        optimisation and further development. One of the most
                     as well as Post Docs and       powerful tools to do this is to analyse the kinetic profile
                     PhD students who have          of the reaction; however, synthetic chemists often view
                     the curiosity to develop a     kinetics, and the general field of physical organic chemistry,
                     more intimate knowledge        with trepidation.
                     of their reactions and
                     provide the groundwork         The aim of this one day taught course is to provide synthetic
                     to undertake mechanistic       chemists with an introduction to the physical tools and
                     investigation.                 methods available to determine and understand reaction
                                                    kinetics. A case study will also be provided to exemplify the
                                                    power of kinetic analysis in reaction development.

         sponsors
                                                         Organising
                                                         Committee




                                                                      Jon Burton, University of Oxford
                                                                      Dave Carbery, University of Bath
                                                                      John Dallimore, Syngenta
                                                                      Nick Tomkinson, Cardiff University



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