Marijuana

From Wikipedia, the free encyclopedia Cannabis (drug) Cannabis (drug) Cannabis A dried flowered bud of the Cannabis sativa plant. Note the visible trichomes (commonly referred to as crystals), which carry a large portion of the drug content. Scientific classification Kingdom: Division: Class: Order: Family: Genus: Species: Plantae Magnoliophyta Magnoliopsida Rosales Cannabaceae Cannabis C. sativa resinous form, known as hashish,[3] consists primarily of glandular trichomes collected from the same plant material. The major biologically active chemical compound in cannabis is Δ9-tetrahydrocannabinol (delta-9-tetrahydrocannabinol), commonly referred to as THC. Humans’ consumption of cannabis predates history.[4] In the 20th century there was a considerable increase in its use for recreational, religious or spiritual, and medicinal purposes. It is estimated that about four percent of the world’s adult population (162 million) use cannabis annually and 0.6 percent (22.5 million) daily.[5] The possession, use, or sale of psychoactive cannabis products became illegal in most parts of the world in the early 20th century. Since then, some countries have intensified the enforcement of cannabis prohibition while others have reduced the priority of enforcement. Forms Flowers Binomial name Cannabis sativa Linnaeus Subspecies C. sativa L. subsp. sativa C. sativa L. subsp. indica Cannabis, also known as marijuana[1], marihuana,[2] or ganja (from Sanskrit: ????? gañjā, hemp) refers to any number of preparations of the cannabis plant intended for human consumption as a drug, the most common of which being the natural herbal form. The herbal form of the drug consists of mature female flowers and sub-tending leaves of pistillate (female) plants. The Cannabis flower • Cannabis, Marijuana or ganja: the flowering tops of female plants,[6] from less than 1% THC to 22% THC; the wide range is probably one of the reasons for the conflicting results from different studies. 1 From Wikipedia, the free encyclopedia Psychoactive potency by cannabis plant part is approximately as follows (descending order):[7] 1. Trichomes 2. Female flowering buds 3. Male flowering buds 4. New shoots 5. Leaves from flower buds 6. Leaves in ascending order of size 7. Stems of leaves (petioles) in ascending order of size 8. Stems in ascending order of size 9. Roots and seeds Cannabis (drug) Hash Oil proportion of cannabinoids (ranging from 40-90%). [10] Hashish Resin Hashish Resin collected from a pipe • Hashish (pressed kief) or charas: a concentrated resin composed of heated glandular trichomes that have been physically extracted,[8] usually by rubbing, sifting, or with ice. Because of THC’s adhesive properties, resin builds up inside the paraphernalia when marijuana is smoked. It has tar-like properties but still contains THC as well as other cannibinoids. This resin still has all the psychoactive properties of marijuana but is harsher and less healthy on the lungs. Marijuana users typically only smoke resin as a last resort when they have run out of marijuana flowers.[11] Kief • Moroccan hashish produced in the Rif mountains;[9] • Sifted cannabis trichomes consisting of only the glandular "heads" (often incorrectly referred to as "crystals" or "pollen"); • These trichomes can also be pressed together under pressure to make hashish. Methods of consumption Cannabis is consumed in many different ways, most of which either involve inhaling smoke from ignited plant or administering orally. Various devices exist for smoking cannabis. The most commonly used include screened bowls, bongs, chillums, paperwrapped joints and cigar-leaf-wrapped Hash oil Hash oil, or honey oil, is an essential oil extracted from the cannabis plant through the use of various solvents. It has a high 2 From Wikipedia, the free encyclopedia Cannabis (drug) Smoking cannabis in hot-burning papers is potentially the most harmful method of consuming cannabis-- burning temperature can reach 700°C.=1292°F.°[1] A screened, narrow single-toke utensil, such as the traditional midwakh (shown here) or kiseru, provides low-temperature 25-mg. (1/ 40-g.) servings, avoiding health risk (and THC waste) of hot-burning cigarette papers or big-bowl pipes. 0.02 mmHg pressure, and somewhat higher at standard atmospheric pressure),[12][13] A lower proportion of toxic chemicals are released than by smoking, although this may vary depending on the design of the vaporizer and the temperature at which it is set. This method of consuming cannabis produces markedly different effects than smoking due to the flash points of different cannabinoids; for example, cannabinol has a flash point of 212.7 °C[14] and would normally be present in smoke but might not be present in vapor. As an alternative to smoking, cannabis may be consumed orally. However, the cannabis or its extract must be sufficiently heated or dehydrated to cause A Volcano forced-air Vaporizer blunts. Local methods differ by the preparation of the cannabis plant before use, the parts of the cannabis plant which are used, and the treatment of the smoke before inhalation. The vaporizer heats herbal cannabis to 365–410 °F (185–210 °C), which causes the active ingredients to evaporate into a gas without burning the plant material (the boiling point of THC is 392 °F (200°C) at 3 From Wikipedia, the free encyclopedia decarboxylation of its most abundant cannabinoid, tetrahydrocannabinolic acid, into psychoactive THC.[15] Cannabis material can be leached in highproof spirits (often grain alcohol) to create a tincture referred to as “Green Dragon”. This process is often employed to make use of low-potency stems and leaves. Cannabis can also be consumed as a cannabis tea. THC is lipophilic and only slightly water soluble (with a solubility of 2.8 mg per liter),[16] so tea is made by first dissolving the active components in a fat such as milk, cream, butter, which is mixed with hot water to make a tea. Cannabis (drug) Tetrahydrocannabinol (THC) is the main active compound in cannabis psychomotor coordination, concentration, and short-term episodic and working memory.[18] Long-term effects are less clear. Effects Classification While many drugs clearly fall into the category of either stimulant, depressant, hallucinogen, or antipsychotic, cannabis, containing both THC and CBD, exhibits a mix of all properties, leaning towards hallucinogen properties due to THC being the primary constituent.[19][20][21] Health issues The smoking of cannabis is the most harmful method of consumption, since the inhalation of smoke from organic materials such as cannabis, tobacco, and rolling papers can cause various health problems.[22] In comparison, study on cannabis vaporizing found that subjects were "only 40% as likely to report respiratory symptoms as users who do not vaporize, even when age, sex, cigarette use, and amount of cannabis consumed are controlled."[23] Another study found vaporizers to be "a safe and effective cannabinoid delivery system."[24][25] A 2007 study by the Canadian government found cannabis smoke contained more toxic substances than tobacco smoke.[27] The study determined that marijuana smoke contained 20 times more ammonia, and five times more hydrogen cyanide and nitrogen oxides than tobacco smoke. In spite of this, recent studies have been unable to demonstrate a direct link between lung cancer and frequent direct inhalation of marijuana smoke. While many researchers have failed to find a correlation,[28][29] some researchers still conclude that cannabis smoke poses a higher risk of lung cancer than tobacco.[30] Main short-term somatic (bodily) effects of cannabis. Cannabis has psychoactive and physiological effects when consumed. The minimum amount of THC required to have a perceptible psychoactive effect is about 10 micrograms per kilogram of body weight.[17] Aside from a subjective change in perception, the most common short-term physical and neurological effects include increased heart rate, lowered blood pressure, impairment of 4 From Wikipedia, the free encyclopedia Cannabis (drug) Gateway drug hypothesis Further information: Gateway drug theory Some claim that trying cannabis increases the probability that users will eventually use harder drugs. This hypothesis has been one of the central pillars of anti-cannabis drug policy in the United States,[40] though the validity and implications of these hypotheses are highly debated.[41] Studies have shown that tobacco smoking is a better predictor of concurrent illicit hard drug use than smoking cannabis.[42] No widely accepted study has ever demonstrated a cause-and-effect relationship between the use of cannabis and the later use of harder drugs like heroin and cocaine. However, the prevalence of tobacco cigarette advertising and the practice of mixing tobacco and cannabis together in a single large joint, common in Europe, are believed to be a factor in promoting nicotine dependency among young persons investigating cannabis.[43] A 2005 comprehensive review of the literature on the cannabis gateway hypothesis found that pre-existing traits may predispose users to addiction in general, the availability of multiple drugs in a given setting confounds predictive patterns in their usage, and drug sub-cultures are more influential than cannabis itself. The study called for further research on "social context, individual characteristics, and drug effects" to discover the actual relationships between cannabis and the use of other drugs.[44] The main variant of the gateway hypothesis is that people, upon trying cannabis for the first time and not finding it dangerous, are then tempted to try other, harder drugs. In such a scenario, a new user of cannabis who feels there is a difference between anti-drug information and their own experiences will apply this distrust to public information about other, more powerful drugs. Some studies state that while there is no proof for this gateway theory, young cannabis users should still be considered as a risk group for intervention programs.[45] Other findings indicate that hard drug users are likely to be "poly-drug" users, and that interventions must address the use of multiple drugs instead of a single hard drug.[46] Another gateway hypothesis is that while cannabis is not as harmful or addictive as other drugs, a gateway effect may be Comparison of physical harm and dependence regarding various drugs (the British medical journal The Lancet[26]) Some studies have even shown that the nonintoxicating ingredient CBD found in marijuana may be useful in treating breast cancer.[31] Cannabis use has been assessed by several studies to be correlated with the development of anxiety, psychosis, and depression,[32][33]; however, no causal mechanism has been proven, and the meaning of the correlation and its direction is a subject of debate that has not been resolved in the scientific community. Some studies assess that the causality is more likely to involve a path from cannabis use to psychotic symptoms rather than a path from psychotic symptoms to cannabis use,[34] while others assess the opposite direction of the causality, or hold cannabis to only form parts of a "causal constellation", while not inflicting mental health problems that would not have occurred in the absence of the cannabis use.[35][36] Though cannabis use has at times been associated with stroke, there is no firmly established link, and potential mechanisms are unknown.[37] Similarly, there is no established relationship between cannabis use and heart disease, including exacerbation of cases of existing heart disease.[38] Though some fMRI studies have shown changes in neurological function in long term heavy cannabis users, no long term behavioral effects after abstinence have been linked to these changes.[39] 5 From Wikipedia, the free encyclopedia detected as a result of the "common factors" involved with using any illegal drug. Because of its illegal status, cannabis users are more likely to be in situations which allow them to become acquainted with people who use and sell other illegal drugs.[47][48] By this argument, some studies have shown that alcohol and tobacco may be regarded as gateway drugs.[42] However, a more parsimonious explanation could be that cannabis is simply more readily available (and at an earlier age) than illegal hard drugs, and alcohol/tobacco are in turn easier to obtain earlier than cannabis (though the reverse may be true in some areas), thus leading to the "gateway sequence" in those people who are most likely to experiment with any drug offered.[41] Cannabis (drug) Cannabis was also known to the ancient Assyrians, who discovered its psychoactive properties through the Aryans.[54] Using it in some religious ceremonies, they called it qunubu (meaning "way to produce smoke"), a probable origin of the modern word ’Cannabis’.[55] Cannabis was also introduced by the Aryans to the Scythians and Thracians/Dacians, whose shamans (the kapnobatai—“those who walk on smoke/ clouds”) burned cannabis flowers to induce a state of trance.[56] Members of the cult of Dionysus, believed to have originated in Thrace (Bulgaria, Greece and Turkey), are also thought to have inhaled cannabis smoke. In 2003, a leather basket filled with cannabis leaf fragments and seeds was found next to a 2,500- to 2,800-year-old mummified shaman in the northwestern Xinjiang Uygur Autonomous Region of China.[57][58] History The use of cannabis, at least as fiber, has been shown to go back at least 10,000 years in Taiwan.[49] Má (Pinyin pronunciation), the Chinese expression for hemp, is a pictograph of 2 plants under a shelter.[50] Evidence of the inhalation of cannabis smoke can be found as far back as the 3rd millennium BC as indicated by charred cannabis seeds found in a ritual brazier at an ancient burial site in present day Romania.[4] The most famous users of cannabis were the ancient Hindus of India and Nepal. The herb was called ganjika in Sanskrit (?????/????? ganja in modern Indic languages).[51][52] The ancient drug soma, mentioned in the Vedas as a sacred intoxicating hallucinogen, was sometimes associated with cannabis.[53] Cannabis sativa from Vienna Dioscurides, 512 A.D. Cannabis has an ancient history of ritual use and is found in pharmacological cults around the world. Hemp seeds discovered by archaeologists at Pazyryk suggest early ceremonial practices like eating by the Scythians occurred during the 5th to 2nd century BCE, confirming previous historical reports by Herodotus.[59] One writer has claimed that cannabis was used as a religious sacrament by ancient Jews and early Christians[60] due 6 From Wikipedia, the free encyclopedia to the similarity between the Hebrew word qannabbos (cannabis) and the Hebrew phrase qené bósem (aromatic cane). It was used by Muslims in various Sufi orders as early as the Mamluk period, for example by the Qalandars.[61] Cannabis became illegal in the USA in 1937 due to Marihuana Tax Act of 1937 . Several theories try to explain why it is illegal in most Western societies. Jack Herer, a cannabis legalization activist and writer, argues that the economic interests of the paper and chemical industry were a driving force to make it illegal. [62][63][64] Another explanation is that beneficial effects of hemp would lower the profit of pharmaceutical companies which therefore have a vital interest to keep cannabis illegal.[65] Those economic theories were criticized for not taking social aspect into account. The illegalization was rather a result of racism directed to associate American immigrants of Mexican and African descent with cannabis abuse.[66] Today, recreational use in the Western world drives a sizable demand for the drug. Cannabis is the largest cash crop in the United States, generating an estimated $36 billion market.[67] Most of the money is spent not on growing and producing but on smuggling the supply to buyers. The European Monitoring Centre for Drugs and Drug Addiction reports that typical retail prices in Europe for cannabis varies from 2€ to 14€ per gram, with a majority of European countries reporting prices in the range 4–10€.[68] The United Nations Office on Drugs and Crime claims in its 2008 World Drug Report that typical US retail prices are 15 dollars per gram (approximately $430 per ounce).[69] Cannabis (drug) investigations into the medical uses of cannabinoids.[70] Comparable authorities in Western Europe, including the Netherlands, have not approved smoked cannabis for any condition or disease. In a collection of writings on medical marijuana by 45 researchers, a literature review on the medicinal uses of cannabis and cannabinoids concluded that established uses include easing of nausea and vomiting, anorexia, and weight loss; "well-confirmed effect" was found in the treatment of spasticity, painful conditions (i.e. neurogenic pain), movement disorders, asthma, and glaucoma. Reported but "less-confirmed" effects included treatment of allergies, inflammation, infection, epilepsy, depression, bipolar disorders, anxiety disorder, dependency and withdrawal. Basic level research was being carried out at the time on autoimmune disease, cancer, neuroprotection, fever, disorders of blood pressure.[71] Clinical trials conducted by the American Marijuana Policy Project, a pro-cannabis organization, have shown the efficacy of cannabis as a treatment for cancer and AIDS patients, who often suffer from clinical depression, and from nausea and resulting weight loss due to chemotherapy and other aggressive treatments.[72] A synthetic version of the cannabinoid THC named dronabinol has been shown to relieve symptoms of anorexia and reduce agitation in elderly Alzheimer’s patients.[73] Dronabinol has been approved for use with anorexia in patients with HIV/AIDS and chemotherapy-related nausea. This drug, while demonstrating the effectiveness of cannabis at combating several disorders, is more expensive and less available than "pot" and has not been shown to be effective or safe.[74] Glaucoma, a condition of increased pressure within the eyeball causing gradual loss of sight, can be treated with medical marijuana to decrease this intraocular pressure. There has been debate for 25 years on the subject. Some data exist, showing a reduction of IOP in glaucoma patients who smoke cannabis,[75] but the effects are shortlived, and the frequency of doses needed to sustain a decreased IOP can cause systemic toxicity. There is also some concern over its use since it can also decrease blood flow to the optic nerve. Marijuana lowers IOP by acting on a cannabinoid receptor on the ciliary body called the CB receptor.[76] Although Medical use A synthetic form of one chemical in cannabis, Δ9-tetrahydrocannabinol (THC), is used as a treatment for a wide range of medical conditions. In the United States, although the FDA does acknowledge that "there has been considerable interest in its use for the treatment of a number of conditions, including glaucoma, AIDS wasting, neuropathic pain, treatment of spasticity associated with multiple sclerosis, and chemotherapy-induced nausea," the agency has not approved "medical marijuana". The FDA does facilitate scientific 7 From Wikipedia, the free encyclopedia cannabis is not a good therapeutic choice for glaucoma patients, it may lead researchers to more effective, safer treatments. A promising study shows that agents targeted to ocular CB receptors can reduce IOP in glaucoma patients who have failed other therapies.[77] Medical cannabis is also used for analgesia, or pain relief. It is also reported to be beneficial for treating certain neurological illnesses such as epilepsy, and bipolar disorder.[78] Case reports have found that cannabis can relieve tics in people with obsessive compulsive disorder and Tourette syndrome. Patients treated with tetrahydrocannabinol, the main psychoactive chemical found in cannabis, reported a significant decrease in both motor and vocal tics, some of 50% or more.[79][80][81] Some decrease in obsessive-compulsive behavior was also found.[79] A recent study has also concluded that cannabinoids found in cannabis might have the ability to prevent Alzheimer’s disease.[82] THC has been shown to reduce arterial blockages.[83] Another potential use for medical cannabis is movement disorders. cannabis is frequently reported to reduce the muscle spasms associated with multiple sclerosis; this has been acknowledged by the Institute of Medicine, but it noted that these abundant anecdotal reports are not well-supported by clinical data. Evidence from animal studies suggests that there is a possible role for cannabinoids in the treatment of certain types of epileptic seizures.[84] A synthetic version of the major active compound in cannabis, THC, is available in capsule form as the prescription drug dronabinol (Marinol) in many countries. The prescription drug Sativex, an extract of cannabis administered as a sublingual spray, has been approved in Canada for the treatment of multiple sclerosis.[85] Cannabis (drug) Cannabis plant the potency of cannabis since the late 1960s and early ’70s, when Δ9-tetrahydrocannabinol was discovered and understood. However, potent seedless marijuana such as "Thai sticks" were already available at that time. In fact, the sinsemilla technique of producing high-potency cannabis has been practiced in India for centuries. Sinsemilla (Spanish for "without seed") is the dried, seedless inflorescences of female cannabis plants. Because THC production drops off once pollination occurs, the male plants (which produce little THC themselves) are eliminated before they shed pollen to prevent pollination. Advanced cultivation techniques such as hydroponics, cloning, high-intensity artificial lighting, and the sea of green method are frequently Demographics Further information: Adult lifetime cannabis use by country, Annual cannabis use by country New breeding and cultivation techniques It is often claimed by growers and breeders of herbal cannabis that advances in breeding and cultivation techniques have increased 8 From Wikipedia, the free encyclopedia employed as a response (in part) to prohibition enforcement efforts that make outdoor cultivation more risky. These intensive horticultural techniques have made it possible to grow strains with fewer seeds and higher potency. It is often cited that the average levels of THC in cannabis sold in United States rose dramatically between the 1970s and 2000, but such statements are likely skewed because of undue weight given to much more expensive and potent, but less prevalent samples.[86] "Skunk" cannabis is a potent strain of cannabis, grown through selective breeding and usually hydroponics, that is a cross-breed of Cannabis sativa and C. indica. Skunk cannabis potency ranges usually from 6% to 15% and rarely as high as 20%. The average THC level in coffeehouses in the Netherlands is about 18–19%.[87] In revisions to cannabis rescheduling in the UK, the government has rescheduled cannabis back from C to B. One of the purported reasons is the high-potency cannabis.[88] A Dutch double-blind, randomized, placebo-controlled, cross-over study examining male volunteers aged 18–45 years with a self-reported history of regular cannabis use concluded that smoking of cannabis with high THC levels (marijuana with 9–23% THC), as currently sold in coffee shops in the Netherlands, may lead to higher THC bloodserum concentrations. This is reflected by an increase of the occurrence of impaired psychomotor skills, particularly among younger or inexperienced cannabis smokers, who do not adapt their smoking-style to the higher THC content.[89] High THC concentrations in cannabis was associated with a dose-related increase of physical effects (such as increase of heart rate, and decrease of blood pressure) and psychomotor effects (such as reacting more slowly, being less concentrated, making more mistakes during performance testing, having less motor control, and experiencing drowsiness). It was also observed during the study that the effects from a single joint at times lasted for more than eight hours. Reaction times remained impaired five hours after smoking, when the THC serum concentrations were significantly reduced, but still present. The researchers suggested that THC may accumulate in blood-serum when cannabis is smoked several times per day. Cannabis (drug) Another study showed that consumption of 15 mg of Δ9-THC resulted in no learning whatsoever occurring over a three-trial selective reminding task after two hours. In several tasks, Δ9-THC increased both speed and error rates, reflecting “riskier” [90] speed–accuracy trade-offs. Various strains of cannabis Further information: Cannabis strains There are hundreds of named strains of Cannabis, but their origins (particularly the drug varieties) are often shrouded in mystery. The names of many legendary strains, such as Panama Red and Purple Haze, are ubiquitous in the pop-culture, but the origins of some of these infamous strains, such as G-13, are acknowledged to be urban legends, and some people even doubt their existence.[91] Strains of Cannabis: • Acapulco gold • BC Bud • Cinderella 99 • Chocolate Thai • Panama Red • G-13 • Kush • Northern Lights • Purple Haze • Quebec Gold • White Widow The names of some strains have become embedded in the mass culture. For example, Chocolate Thai,[92] which was popular in the early 1990s due to its supposed high potency,[93] was adopted as the stage name of a jazz performer whose album The Real McCoy was released in 2006.[94] It should be noted, however, that because there is no state control over the production or sale of Cannabis, many "strains" may in fact be just marketing brands adopted by drug dealers to increase sales. Legal status See also: Drug prohibition and Drug liberalization Since the beginning of the 20th century, most countries have enacted laws against the cultivation, possession, or transfer of cannabis for recreational use. These laws have impacted adversely on the cannabis plant’s 9 From Wikipedia, the free encyclopedia Cannabis (drug) Gnostic Christian sects have asserted that cannabis is the Tree of Life.[100][101] Other organized religions founded in the 20th century that treat cannabis as a sacrament are the THC Ministry,[102] the Way of Infinite Harmony, Cantheism,[103] the Cannabis Assembly[104] and the Church of Cognizance. Truth serum 1935 propaganda sheet cultivation for non-recreational purposes, but there are many regions where, under certain circumstances, handling of cannabis is legal or licensed. Many jurisdictions have lessened the penalties for possession of small quantities of cannabis, so that it is punished by confiscation or a fine, rather than imprisonment, focusing more on those who traffic the drug on the black market. In some areas where cannabis use has been historically tolerated, some new restrictions have been put in place, such as the closing of coffee shops near the borders of the Netherlands,[95] closing of coffees shops near secondary schools in the Netherlands and crackdowns on "Pusher Street" in Christiania, Copenhagen in 2004.[96][97] Some jurisdictions use free voluntary treatment programs and/or mandatory treatment programs for frequent known users. Simple possession can carry long prison terms in some countries, particularly in East Asia, where the sale of cannabis may lead to a sentence of life in prison or even execution. Cannabis female flowers closeup with trichomes (white). These plant parts contain the highest concentration of psychoactive compounds. Cannabis was used as a truth serum by the Office of Strategic Services (OSS), a US government intelligence agency formed during World War II. In the early 1940s, it was the most effective truth drug developed at the OSS labs at St. Elizabeths Hospital; it caused a subject "to be loquacious and free in his impartation of information."[105] In May 1943, Major George Hunter White, head of OSS counter-intelligence operations in the US, arranged a meeting with Augusto Del Gracio, an enforcer for gangster Lucky Luciano. Del Gracio was given cigarettes spiked with THC concentrate from cannabis, and subsequently talked openly about Luciano’s heroin operation. On a second occasion the dosage was increased such that Del Gracio passed out for two hours.[105] Religious use In India and Nepal, cannabis has been used by some of the wandering Hindu spiritual sadhus for centuries, and in modern times the Rastafari movement has embraced it as a sacrament.[98] Elders of the modern religious movement known as the Ethiopian Zion Coptic Church consider cannabis to be the Eucharist, claiming it as an oral tradition from Ethiopia dating back to the time of Christ, even though the movement was founded in the United States in 1975 and has no ties to either Ethiopia or the Coptic Church.[99] Like the Rastafari, some modern Adulterants Adulterants in cannabis are less common than in other drugs of abuse. Chalk (in the Netherlands) and glass particles (in the UK) have been used at times to make cannabis appear to be higher quality.[106][107][108] Increasing the weight of hashish products in 10 From Wikipedia, the free encyclopedia Germany with lead caused lead intoxication in at least 29 users.[109] In the Netherlands two chemical analogs of Sildenafil (Viagra) were found in adulterated marihuana.[110] Occasionally, claims have been made that a ’hard drug’ (such as heroin or cocaine) is added to cannabis, possibly in order to get the users addicted to a drug that is less addictive. However, this is considered a myth as the ’hard drugs’ usually cost more gramfor-gram than ’soft drugs’ so the dealer would lose money on such an operation. Cannabis (drug) [5] United Nations Office on Drugs and Crime (2006), "Cannabis: Why we should care" (PDF), World Drug Report (S.l.: United Nations) 1, ISBN 9-2114-8214-3, http://www.unodc.org/pdf/WDR_2006/ wdr2006_chap2_biggest_market.pdf, retrieved on 2006-10-10 p. 14. [6] "Marijuana- Definitions from Dictionary.com". dictionary.reference.com. http://dictionary.reference.com/browse/ Marijuana. Retrieved on 2008-06-23. [7] "Marijuana Potency". 64.233.167.104. http://64.233.167.104/ search?q=cache:XN8MfdrQC5MJ:www.greenmanspa Cannabis plant guides/ • Cannabis strains thcpotency.html+cannabis+plant+parts+by+potenc • Hemp Retrieved on 2008-07-13. • Hemp oil (a cannabis food product, [8] "Hashish - Definitions from industrial feed stock, and biofuel Dictionary.com". precursor) dictionary.reference.com. • Marijuana (etymology) http://dictionary.reference.com/browse/ • THC Hashish. Retrieved on 2008-06-23. Health [9] Zijlma, Anouk. "Smoking hashish in • Cannabis use disorders Morocco". About.com. • Medical Cannabis http://goafrica.about.com/od/morocco/a/ Cannabis policy moroccokif.htm. Retrieved on • 1937 Marihuana Tax Act 2007-02-27. • Cannabis political parties [10] "Hash oil info". http://www.a1b2c3.com/ • Global Marijuana March drugs/hash005.htm. Retrieved on • International Opium Convention 2009-05-11. • Legal and medical status of cannabis [11] "Pipe Residue Information". • Legality of cannabis by country http://www.cannabisculture.com/v2/ • Marijuana Control, Regulation, and articles/3603.html. Retrieved on Education Act 2004-08-25. • Marijuana Policy Project [12] "Air Temperature Table". • National Organization for the Reform of http://www.webcitation.org/5g6b2TjN3. Marijuana Laws Retrieved on 2007-09-22. . Volcanotm Operating Manual. Storz & Bickel, Tuttlingen, Germany. [13] 1989. The Merck Index, 11th ed., Merck [1] Compact Oxford Dictionary definition & Co., Rahway, New Jersey. [2] derived from the Spanish, also spelled [14] http://www.chemspider.com/Chemical"mariguana", which is of unknown origin Structure.2447.html ( Spanish Word Histories and Mysteries. [15] "Does marijuana have to be heated to p. 142. http://books.google.com/ become psychoactive?" books?id=VTYBbGybtNEC&pg=PA142&lpg=PA142&dq=%2Bmarijuana+%2B%22spanish+word%22 [16] "ChemIDplus Lite". chem.sis.nlm.nih.gov. GNnDA2APJX7BUCM&hl=en&sa=X&oi=book_result&resnum=9&ct=result. ) http://chem.sis.nlm.nih.gov/chemidplus/ [3] Matthew J. Atha - Independent Drug ProxyServlet?objectHandle=Search&actionHandle=g Monitoring Unit. "Types of Cannabis Retrieved on 2008-08-08. Available in the UK". [17] http://www.marijuanalibrary.org/ http://www.idmu.co.uk/can.htm. brain2.txt Retrieved on 2007-09-13. [18] Riedel G, Davies SN (2005). [4] ^ Rudgley, Richard (1998). Lost "Cannabinoid function in learning, Civilisations of the Stone Age. New York: memory and plasticity". Handb Exp Free Press. ISBN 0-6848-5580-1. Pharmacol (168): 445–77. PMID See also References 11 From Wikipedia, the free encyclopedia Cannabis (drug) 16596784. http://www.springerlink.com/ 2006/05/060526083353.htm. Retrieved openurl.asp?genre=chapter&issn=0171-2004&volume=&page=445. on 2009-04-17. [19] McKim, William A (2002). Drugs and [29] "Study Finds No Cancer-Marijuana Behavior: An Introduction to Behavioral Connection". Washington Post. Pharmacology (5th Edition). Prentice [2006-5-26]. Hall. p. 400. ISBN 0-13-048118-1. http://www.washingtonpost.com/wp-dyn/ [20] "Information on Drugs of Abuse". content/article/2006/05/25/ Commonly Abused Drug Chart. AR2006052501729_pf.html. Retrieved on http://www.nida.nih.gov/DrugPages/ 2009-04-17. DrugsofAbuse.html. Retrieved on July 15, [30] "Cannabis bigger cancer risk than 2007. cigarettes: study". Thomson Reuters. [21] Stafford, Peter (1992). Psychedelics http://www.reuters.com/article/ Encyclopedia. Berkeley, CA: Ronin Pub.. healthNews/idUSHKG10478820080129. ISBN 0914171518. Retrieved on 2008-12-02. [22] "The Haworth Press Online Catalog: [31] "Marijuana compound may stop spread Article Abstract". of breast cancer". Fox News. 2007-11-19. www.haworthpress.com. http://www.foxnews.com/story/ http://www.informaworld.com/smpp/ 0,2933,312132,00.html. Retrieved on content~db=all?content=10.1300/ 2009-04-17. J175v01n03_09. Retrieved on [32] Henquet C, Krabbendam L, Spauwen J, 2008-07-28. et al. (January 2005). "Prospective cohort [23] "Harm Reduction Journal". study of cannabis use, predisposition for harmreductionjournal.com. psychosis, and psychotic symptoms in http://harmreductionjournal.com/ young people". BMJ 330 (7481): 11. content/4/1/11. Retrieved on doi:10.1136/bmj.38267.664086.63. PMID 2008-07-28. 15574485. [24] Abrams DI, Vizoso HP, Shade SB, Jay C, [33] Patton GC, Coffey C, Carlin JB, Kelly ME, Benowitz NL (November Degenhardt L, Lynskey M, Hall W 2007). "Vaporization as a smokeless (November 2002). "Cannabis use and cannabis delivery system: a pilot study". mental health in young people: cohort Clin. Pharmacol. Ther. 82 (5): 572–8. study". BMJ 325 (7374): 1195–8. doi:10.1038/sj.clpt.6100200. PMID doi:10.1136/bmj.325.7374.1195. PMID 17429350. 12446533. [25] "Evaluation of a vaporizing device [34] Fergusson DM, Horwood LJ, Ridder EM (Volcano®) for the pulmonary (March 2005). "Tests of causal linkages administration of tetrahydrocannabinol". between cannabis use and psychotic cat.inist.fr. http://cat.inist.fr/ symptoms". Addiction 100 (3): 354–66. ?aModele=afficheN&cpsidt=17821306. doi:10.1111/j.1360-0443.2005.01001.x. Retrieved on 2008-07-28. PMID 15733249. [26] Nutt D, King LA, Saulsbury W, [35] Hall, Wayne; Degenhardt, Lousia; Blakemore C (March 2007). Teesson, Maree. "Cannabis use and "Development of a rational scale to psychotic disorders: an update". Office of assess the harm of drugs of potential Public Policy and Ethics, Institute for misuse". Lancet 369 (9566): 1047–53. Molecular Bioscience University of doi:10.1016/S0140-6736(07)60464-4. Queensland Australia, and National Drug PMID 17382831. and Alcohol Research Centre University http://www.antiproibizionisti.it/public/ of New South Wales Australia published docs/thelancet_20070323.pdf. edit in Drug and Alcohol Review (December [27] "Cannabis smoke ’has more toxins’". 2004). Vol 23 Issue 4. pp. 433-443. BBC. 2007-12-19. http://news.bbc.co.uk/ [36] Arseneault, Louise; Cannon, Mary; 2/hi/health/7150274.stm. Wiitton, John; Murray, Robin M. "Causal [28] "Study Finds No Link Between Marijuana association between cannabis and Use And Lung Cancer". Science Daily. psychosis:Causal association between 2006-05-26. cannabis and psychosis: examination of http://www.sciencedaily.com/releases/ the evidence". Institute of Psychiatry 12 From Wikipedia, the free encyclopedia published in British Journal of Psychiatry (2004). #184, pp. 110-117. [37] Thanvi, B.R.; Treadwell, S.D. (2009), "Cannabis and stroke: is there a link?", British Medical Journal 85 (1000): 80, http://pmj.bmj.com/cgi/content/abstract/ 85/1000/80, retrieved on 2009-04-26 [38] Mukamal, K.J.; MacLure, M.; Muller, J.E.; Mittleman, M.A. (2008), "An exploratory prospective study of marijuana use and mortality following acute myocardial infarction.", American Heart Journal 155 (3): 465, http://files.shroomery.org/ attachments/ 8327648-Mukamal_Kenneth_J.pdf, retrieved on 2009-04-26 [39] Gonzalez, R. (2007), "Acute and Nonacute Effects of Cannabis on Brain Functioning and Neuropsychological Performance", Neuropsychology Review 17 (3): 347–361, http://www.springerlink.com/index/ b430083r47676650.pdf, retrieved on 2009-04-26 [40] Lundin, Leigh (2009-03-01). "The Great Smoke-Out". Criminal Brief. http://www.criminalbrief.com/?p=5445. Retrieved on 2009-03-14. [41] ^ "RAND study casts doubt on claims that marijuana acts as "gateway" to the use of cocaine and heroin". RAND Corporation. 2002-12-02. http://www.rand.org/news/press.02/ gateway.html. Retrieved on 2007-02-27. [42] ^ Torabi MR, Bailey WJ, Majd-Jabbari M (1993). "Cigarette smoking as a predictor of alcohol and other drug use by children and adolescents: evidence of the "gateway drug effect"". The Journal of school health 63 (7): 302–6. PMID 8246462. [43] Australian Government Department of Health: National Cannabis Strategy Consultation Paper, p. 4. "Cannabis has been described as a ’Trojan Horse’ for nicotine addiction, given the usual method of mixing cannabis with tobacco when preparing marijuana for administration." [44] "Is cannabis a gateway drug? Testing hypotheses about the relationship between cannabis use and the use of other illicit drugs - UQ eSpace". espace.library.uq.edu.au. http://espace.library.uq.edu.au/view/ UQ:75835. Retrieved on 2008-06-19. Cannabis (drug) [45] Saitz, Richard (2003-02-18). "Is marijuana a gateway drug?". Journal Watch. http://generalmedicine.jwatch.org/cgi/content/full/ 2003/218/1. Retrieved on 2007-02-27. [46] Degenhardt, Louisa et al. (2007). "Who are the new amphetamine users? A 10-year prospective study of young Australians". http://www.blackwellsynergy.com/doi/abs/10.1111/ j.1360-0443.2007.01906.x. Retrieved on 2007-09-22. [47] Morral AR, McCaffrey DF, Paddock SM (2002). "Reassessing the marijuana gateway effect". Addiction 97 (12): 1493–504. doi:10.1046/ j.1360-0443.2002.00280.x. PMID 12472629. http://www3.interscience.wiley.com/ journal/118957921/abstract. [48] "Marijuana Policy Project- FAQ". http://www.mpp.org/about/faq.html. Retrieved on 2006-12-24. [49] Stafford, Peter. 1992. Psychedelics Encyclopedia. Berkeley, California, Ronin Publishing, Inc. ISBN 0-914171-51-8 [50] Matthews, A.; Matthews, L. (2007), Learning Chinese Characters, p. 336, http://books.google.com/ books?id=YweFHwPd05EC&pg=PA336&lpg=PA336 LOmhqDPr74RhgJPmOVm8&hl=en&sa=X&oi=book_ [51] Leary, Thimothy (1990). Tarcher/ Putnam. ed. Flashbacks. New York: G.P. Putnam’s Sons. ISBN 0-8747-7870-0. [52] Miller, Ga (December 1911), "Encyclopædia Britannica", Science (New York, N.Y.) 34 (883): 761–762, doi:10.1126/science.34.883.761, PMID 17759460, http://www.1911encyclopedia.org/Hemp, retrieved on 2006-06-15 . [53] Rudgley, Richard (1998). Little, Brown and Company. ed. The Encyclopedia of Psychoactive Substances. http://www.huxley.net/soma/index.html. Retrieved on 2007-02-25. [54] Franck, Mel (1997). Marijuana Grower’s Guide. Red Eye Press. ISBN 0-9293-4903-2. p. 3. [55] Rubin, Vera D. (1976). Cannabis and Culture. Campus Verlag. ISBN 3-5933-7442-0. p. 305. [56] Cunliffe, Barry W. (2001). The Oxford Illustrated History of Prehistoric Europe. Oxford University Press. ISBN 0-1928-5441-0. p. 405. 13 From Wikipedia, the free encyclopedia Cannabis (drug) [57] "Lab work to identify 2,800-year-old United Nations Publications. p. 264. mummy of shaman". People’s Daily ISBN 978-92-1-148229-4. Online. 2006. http://www.unodc.org/documents/wdr/ http://english.peopledaily.com.cn/ WDR_2008/WDR_2008_eng_web.pdf. 200612/23/eng20061223_335258.html. Retrieved on 2009-04-17. Retrieved on 2007-02-25. [70] Meyer, Robert J. [http://www.fda.gov/ola/ [58] Hong-En Jiang et al. (2006). "A new 2004/marijuana0401.html "Testimony insight into Cannabis sativa before the Subcommittee on Criminal (Cannabaceae) utilization from Justice, Drug Policy, and Human 2500-year-old Yanghai tombs, Xinjiang, Resources, Committee on Government China". Journal of Ethnopharmacology Reform"]. U.S. Food and Drug Administration. http://www.fda.gov/ola/ 108 (3): 414–422. doi:10.1016/ 2004/marijuana0401.html. Retrieved on j.jep.2006.05.034. 2007-09-15. http://www.sciencedirect.com/ [71] Grotenhermen, F.; Russo, E. (2002). science?_ob=ArticleURL&_udi=B6T8D-4K7WC0F-2&_user=10&_coverDate=12%2F06%2F2006&_rdo "Chapter 11, Review of therapeutic info(%23toc%235084%232006%23998919996%23636769%23FLA%23display%23Volume)&_cdi=508 effects". Cannabis and cannabinoids: Retrieved on 2007-02-25. pharmacology, toxicology, and [59] Walton, Robert P. (1938). Marijuana, therapeutic potential. Haworth Press. p. America’s New Drug Problem. J. B. 123. ISBN 0789015080. Lippincott. p. 6. http://books.google.co.uk/books?hl=en. [60] "Cannabis linked to Biblical healing". Retrieved on 2009-05-18. http://news.bbc.co.uk/2/hi/health/ [72] Low-Dose Pot Eases Pain While Keeping 2633187.stm. Retrieved on 2007-08-20. Mind Clear [61] Ibn Taymiyya (2001). Le haschich et [73] "Cannabis lifts Alzheimer appetite". BBC. l’extase. Beyrouth: Albouraq. ISBN http://news.bbc.co.uk/1/hi/health/ 2-8416-1174-4. 3169901.stm. Retrieved on 2007-09-15. [62] Marijuana Conspiracy - by Dough [74] Greenberg, Gary (2005-11-01). Yurchey "Respectable Reefer". Mother Jones. [63] William Randolf Hearst, Lammont http://www.motherjones.com/politics/ Dupont, Henry J. Anslinger, and hemp 2005/11/respectable-reefer?page=3. [Archive] - DiscussAnything.com Retrieved on 2007-04-03. [64]