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							 A Biological Revolution in
 Hydrogen Fuel Production
Principal Investigator:                        IBCS Team:
Dr. Pamela Silver                          Giacomo Centini
Harvard Medical School                         Michael Ellis
Dept. of Systems Biology                      Cedric Lucas
                                                 Yang Mao
                                                  John Wu
                                              Autumn Yuan

                       December 13, 2007
Multiple Methods of Hydrogen Production


   Hydrocarbon                                                                      Biomass         Microbial
   Reformation                              Hydrolysis                              Gasification    Metabolism




   • Cheap                              • More                                  • Cost unclear     • Potentially
   • Energy                               expensive                             • Energy             lowest cost
     intensive                          • Energy                                  intensive        • Least energy
   • High CO2                             intensive                             • Some CO2           intense
     output                             • No CO2 output                           output           • Little to no
   • Non-renewable                      • Potentially                           • Renewable          CO2 output
                                          renewable                                                • Renewable



Source: Interview with George Sverdrup, National Renewable Energy Laboratory; group research
Using Yeast to Produce Hydrogen

     Biomass
   Harvest and                               Sugar                             Fermentation             Hydrogen
    Treatment




                                       Bioengineered
                                           Yeast




                                                                    C6H12O6 → high energy intermediate → H2




Source: Conversation with research team of PI Dr. Pamela Silver’s laboratory
Technology Current Status and IP Considerations

    Current Status                                                                  IP Considerations


    •    There are two different processes                                          •     Provisional Patent has been Filed
         under study to convert sugar to H2 :
                                                                                    •     No publication has been made,
           – Direct : Converting sugar to H2                                              but research abstract has been
                                                                                          displayed at scientific conference
           – Indirect: Converting sugar to
             Formate, then Formate to H2
                                                                                    •     Strong IP protection likely; no
    •    The current yield is 0.05% - 0.1%                                                existing patents related to use of
                                                                                          yeast to convert sugar to H2
    •    Further development is needed in
         order to achieve a reasonable yield
         (15-40%)                                                                   •     Operating indirect process to
                                                                                          convert formate to H2 may require
                                                                                          licensing existing bacteria




Source: Conversation with research team of PI Dr. Pamela Silver’s laboratory; United States Patent and Trademark Office (USPTO),
     http://www.uspto.gov/, accessed November 2007.
 Hydrogen Market Overview
  Key Insights                                                                Current Producers

• Hydrogen:
       – Is difficult to transport
       – Is difficult to store
                                                                           Others
       – Requires major capital infrastructure for                                                      24%
         traditional production                                             36%




• Hydrogen industry highly concentrated

• Plant location is key
                                                                                                              16%
• High barriers to entry
                                                                                            10%
                                                                                                  14%
• Customer base very loyal; more concerned about
  reliability than price




Source: ENEA – Idrocomb - www.krill.net/idrogeno/iacobazzi-1.pdf - Accessed November 2007
   Hydrogen Market Overview (cont’d)
   Current Market: $3B                                                 Potential Market 2020: up to $1.7T


        Methanol;    Other; 4%   Space;                                      Current Uses
          10%                      1%                                            2%




     Refineries;                          Ammonia;
        35%                                 50%

                                                                                                                           Future
                                                                                                                       Transportation
                                                                                                                            98%
     • Current production: 50MT, $3B                                              • Potential market if the global
     • Market growth: 10-20% per year                                               transportation will migrate from
     • Current uses primarily non-energy                                            current gas ICE vehicles to hydrogen
       related:                                                                     fueled vehicles is estimated at over
                                                                                    $1.7T in 2020
              –     Ammonia
              –     Refining
              –     Food production                                               • Fuel Cells and ICE H2 Vehicles are
                                                                                    expected to be the main market for
     • Some energy-related use:
                                                                                    hydrogen in the future
              –     Methanol
              –     Rocket fuel

Source Current Market Data: ITS – www.ieagreen.org.uk/h2ch2.htm - Accessed on November 2007
Source Potential Market Data: Minnesota Department of Commerce -
www.state.mn.us/mn/externalDocs/Commerce/Hydrogen_Potential_090803021706_HydrogenReport4.pdf - Accessed in November 2007
Business Model Options
Options           Pros                            Cons



Large-Scale       • Greatest value add/capture   • Most capital intensive
Facilities        • Flexible outputs possible    • High transportation
                                                   costs




Small-Scale       • Reduces transportation       • High service costs
Bioreactors         costs                        • Difficult to upgrade
                  • Best serves niche markets      distributed tech



                  •   Core competency            • Lower value add/capture
License           •   Serve growing niches
                  •   Provide varied outputs
                  •   Lowest capex


                  • Potentially faster           • Tough to raise capital
Lab Spin-Off        development                  • Less control
                                                 • Less access to Harvard
                                                   resources
Timeline
        2008                        2009                         2010-2012




 Develop Technology          Prove Concept                Find Partners
 • The technology should     • Begin lab-scale pilot      • License to strategic
   be developed further in     production                   partner(s) for:
   Harvard laboratories in                                    – Further development
                             • Aim to generate data
   order to:                                                    of operations
                               enabling greater value
     – Reach yield, cost,      capture from licensees         – Taking product to
       and output              (e.g. cost, reliability,         market reliably and
       milestones              scalability)                     with a strong brand
     – Understand
                                                          • Potential targets:
       possible
       applications given                                     – Entrenched
       purity and pressure                                      producers
       of H2
                                                              – H2 transportation
                                                                fuel startups
Backup Slides
    Description of Innovation

     • Most hydrogen production efforts focused on well-
       understood reaction C6H12O6 (glucose) + H2O
       6CO2 + 12H2
     • Focusing on alternate pathway with more favorable
       economics: NAD(P)H + H+      NAD(P)+ + H2
     • Two parallel development paths
             – Constructing artificial metabolic pathways to generate stronger
               biological reducing agents
             – Constructing artificial organelles (microenvironments within cells)
               in which the NAD(P)H/NAD(P)+ ratio can be made arbitrarily
               high to drive the reaction to the right
     • R&D will also enable more efficient modification of
       metabolic pathways for production of other useful end
       products, including small molecule fuels


Source: Conversation with research team of PI Dr. Pamela Silver’s laboratory
     Technical Feasibility
     •     Stage of development: Early development/proof of concept
            – Provisional patent filed covering biological compositions, systems and methods for producing
               hydrogen using engineered yeast systems, or a combination of an engineered yeast system
               and an engineered bacterial system.
            – Systems have yielded maximum hydrogen conversion yield of 0.1%; target is 40%
     •     Technical roadmap
             – Research milestones




Source: Conversation with research team of PI Dr. Pamela Silver’s laboratory
Technical Feasibility (cont’d)
 – Recommended additional milestones
    • Purity of hydrogen
    • Production capacity: 1 kg/day; 100 kg/day; demonstration of
      scalability to 10,000 kg/day
    • Production cost $10/kg; $5/kg; $2/kg

 – Risks
    • Modification of cell pathways could cause unintended
       consequences that inhibit conversion efficiency yield or hydrogen
       purity
    • Labor intensity and process variability could make system non-
       competitive with traditional modes of hydrogen production
    • Upstream biomass conversion needed for process input could make
       process uneconomical or output too variable in quality
    • Hydrogen production through advanced materials/direct catalysis or
       other production methods could render this process uneconomical
  The Current IP Status and Freedom to Operate

     Related Prior Art                                                           Freedom to Operate

     •    From Sugar to Formate:                                                 •     From Sugar to Formate:
          existing patent covers process for formate                                   will not infringe the existing patent
          production by bacteria (5879915)                                             covering process for formate production
                                                                                       by bacteria (5879915), since yeast is
     •    From Formate to H2:                                                          going to be used instead of bacteria
          public knowledge exists, process for
          anaerobic production of hydrogen using a                               •     From Formate to H2:
          delta-proteobacterium was patented
          (5834264) back in 1998                                                       could infringe the existing patent
                                                                                       covering process for anaerobic
                                                                                       production of hydrogen (5834264) only
     •    Other related prior art:
                                                                                       if the specific delta-proteobacterium(
          existing patent covers process for                                           ATCC 55738) is going to be used, but,
          hydrogen production using hydrogenase-
                                                                                       regular ways of converting formate to
          containing oxygenic photosynthetic
          organisms (6989252, 4442211)                                                 H2 are less economical, as claimed in
                                                                                       the mentioned patent


           Recommendation: Inventors should engineer new strains of bacteria to make the
           conversion of Formate to H2 more efficient and bypass the existing patent, or consider
           licensing the patent mentioned instead

Source: United States Patent and Trademark Office (USPTO), http://www.uspto.gov/, accessed November 2007.
      Hydrogen Market Overview
                                                                                                             Electrolysis,
         Production Method                                                                                       4%
                                                                                                                                 Coal, 18%
         • The current distribution in the production of Hydrogen is driven
           by mainly economic reasons over environmental considerations
         • Currently renewable electrolysis is not economically competitive
           with other form of hydrogen production
         • Other forms of hydrogen production from fermentation to
           photobiological water splitting are under investigation                            Natural Gas,
                                                                                                  48%                        Oil, 30%


                                                   Air
                                                Products,
                                                  24%          Competitors
     Others, 36%

                                                               • The hydrogen production is highly concentrated with the four biggest
                                                                 competitors supplying more than two thirds of the hydrogen worldwide
                                                               • The main player must compete on a global scale, even if certain plant
                                                                 locations are necessary to serve key clients
                                                               • Most of hydrogen producers are highly differentiated in their
                                                   Paraxair,     production
                                                     16%
            BOC, 10%             Air Liquide,
                                     14%



         Key Insight
         • Hydrogen is currently not a viable option for many possible future uses because:
                 – It is difficult to transport : There is no infrastructure available that can be converted to transporting
                    hydrogen as it need specific pressure and temperature requirements
                 – It is very difficult to store : The very small size of the hydrogen molecule make impossible given the
                    current technology to avoid its evaporation from the thank

         • Entering the hydrogen market is very difficult:
                  – The industry is highly concentrated
                  – There are high capital requirements
                  – The customer base tends to be very loyal and more concerned about reliability than price, as
                    hydrogen is a key input but is usually not a significant portion of the cost structure
Source Current Market Data: ITS – www.ieagreen.org.uk/h2ch2.htm - Accessed on November 2007
    Hydrogen Market Development
                                                                                           Other     Space
        • Current production of hydrogen in                              Methanol
          2004 globally was over 50MTwith
          overall revenue of >$3B
        • The industry has been growing on
          average in the last years between
          10% and 20% p.a.
        • Currently most of the hydrogen
          produced is used for non energetic
          uses or indirect energetic uses                             Refineries
                                                                                                                         Ammonia




        Current                                                                    Future

        •   Ammonia:                                                               •   Fuel Cells:
                   Used in the agricultural sector as a fertilizer,                           The main use expected in the future for
                   has seen a rapid growth in recent years due to                             hydrogen, is related to private transportation
                   growing use of fertilizers                                                 with fuel cells vehicles
        •   Refinery:                                                              •   ICE Vehicles:
                   Hydrogen is used to enhance performance of                                 Hydrogen can also be used as propellant for
                   petroleum products by removing organic sulfur                              regular ICE when mixed with natural gases
                   from crude oil, helping refineries to meet Clean                •   Power Storage:
                   Act requirements                                                           Another important use for hydrogen is related
        •   Methanol:                                                                         to the energy storage. This has been proven
                   Used in industrial and chemical applications,                              very effective especially with wind turbines,
                   methanol use has been growing recently due                                 where supply peaks tend not to match demand
                   to its use in the private transportation sector                            peaks
        •   Food:
                   Margarine and butter market have been
                   growing very slowly in the last ten years
        •   Space:
                   Hydrogen is the main propellant for
                   spacecrafts

Source Current Market Data: ITS – www.ieagreen.org.uk/h2ch2.htm - Accessed on November 2007
Source Potential Market Data: Minnesota Department of Commerce -
www.state.mn.us/mn/externalDocs/Commerce/Hydrogen_Potential_090803021706_HydrogenReport4.pdf - Accessed in November 2007
Cost Comparison
 Hydrogen Production Costs                                                                  • To be cost-competitive with
 $/kg                                                                                         dominant production
$8.00
                                                                                              methods, H2 production
$7.00
                                                                                              through yeast must be at
$6.00
                                                                                              $2/kg or less
$5.00                                                                                       • Current estimates of
$4.00                                                                                         hydrogen through other
$3.00                                                                                         biological processes project
$2.00                                                                                         costs of $7.50/kg
$1.00

$0.00
             Gas           Nuclear         Wind        Concentrator PV Flat-Plate
         reformation     electrolysis   electrolysis        PV       Electrolysis               While some of the difference
                                                        electrolysis
                                                                                                may be made up by carbon
                                                                                                credits, significant
                                                                                                progress must be made on
                                                                                                demonstrating much lower
                                                                                                costs through scalable,
                                                                                                reliable technology
Chart data source: “Generating Hydrogen through Water Electrolysis Using Concentrator Photovoltaics.”
R. McConnell and J. Thompson. NREL Conference Paper. January 2005.
Source for other biological process cost: “Updated Cost Analysis of Photobiological Hydrogen Production from Chlamydomonas
reinhardtii Green Algae.” Wade Amos. NREL. January 2004. Average of costs presented on page 26 excluding highest and lowest outliers.
Summary of Potential Business Models
   Business
  Model Option                       Reasons to choose this model                                 Pros                        Cons


  Small scale       • If system is most efficient and reliable at small scale           • Eliminates feedstock       • Service and
  on-site           • If H2 demand grows among fragmented customer base,                  and hydrogen price risk      maintenance costs
  distributed         preferably with feedstock access                                  • Serves growing niche         could be high
  production        • If process costs near or above traditionally produced hydrogen,     markets unlikely to be     • Potential to be
                      but with other advantages valued by customers (e.g., carbon         served by larger             squeezed by system
                      credits)                                                            distributors                 manufacturer and
                                                                                                                       feedstock supplier




  Large scale       • If process is most efficient and reliable at large scale          • Highest potential to add   • Incurs both upstream
  centralized       • If process is cost competitive with traditionally produced          and capture value            (feedstock) and
  production:         hydrogen                                                          • Could enable flexible        downstream (hydrogen)
   Develop and      • If mass market demand grows                                         production of various        price and market risk
   operate                                                                                outputs                    • Longest development
   production                                                                                                          timeline
   facilities



   Develop          • If R&D is yielding multiple technologies that could be licensed   • Closest to existing        • Lower value add; lower
   technology         to numerous bio-chemical/biofuel producers (i.e. beyond             researcher core              potential to capture
   and license to     hydrogen)                                                           competencies                 value
   existing
   producers        • If projected costs of facility construction outweigh projected    • Shortest development
                      profitability                                                       pipeline
                                                                                        • Lightest asset and
                                                                                          capital intensity

Recommended option... but only after technology has been further developed in the lab
Potential Business Models
•   Option 1: Small scale on-site distributed hydrogen production
     – Manufacture and distribute modules that could be installed onsite at point-of-demand to produce 100-5,000
         kg H2/day Revenue:
            • Service and maintenance contracts
            • System (sale or) lease
            • Biomass input (optional)
     – Costs:
            • Capex
                   – System R&D
            • Opex
                   – System manufacture
                   – Continuing system R&D
                   – Service and maintenance staff
                   – Biomass (optional)
     – Reasons to choose this model
            • If system is most efficient and highly reliable at small scale
            • If demand for hydrogen grows among fragmented customer base, preferably with access to feedstock
            • If process costs near or above traditionally produced hydrogen, but with other advantages valued by
               customers (e.g., carbon credits, access to reliable onsite hydrogen production, “greenness” of
               process)
     – Pros
            • Eliminates feedstock and hydrogen price risk
            • Serves growing niche markets unlikely to be served by larger distributors
     – Cons
            • Service and maintenance costs could be high, especially with geographically dispersed customers
            • Potential to be squeezed by system manufacturer (assuming outsourced) and feedstock supplier
     – Complementary assets/technologies
            • Manufacturer (assuming outsourcing of system construction). Not highly specialized; straightforward
               contracting.
            • Distributor of pretreated biomass or supplier of other technology for onsite biomass pretreatment.
               Specialized; likely requires partnership.
Potential Business Models (cont’d)
•   Option 2: Large scale centralized hydrogen production: develop and operate production
    facilities
      – Revenue
             • Hydrogen sale to distributors or direct to customers
      – Costs
             • Capex
             • Process development
             • Facility construction
             • Opex
             • Facility operation
             • Feedstock
             • Biomass
      – Reasons to choose this model
             • If process is highly efficient at large scale
             • If process is cost competitive with traditionally produced hydrogen
             • If mass market demand grows
      – Pros
             • Highest value add; highest potential to capture value
             • Could enable flexible production of various outputs
      – Cons
             • Incurs both upstream (feedstock) and downstream (hydrogen) price risk
             • Longest development timeline
      – Complementary assets/technologies
             • Provider of biomass pretreatment technology. Specialized; likely requires
               partnership.
             • Facility constructor. Not highly specialized; straightforward contracting.
             • Hydrogen distributor. Somewhat specialized.
Potential Business Models (cont’d)
•   Option 3: Large scale centralized hydrogen and other biofuel production: Develop technology
    and license to existing producers
     – Revenue
           • License fees from sale to hydrogen producers or biomass processors
     – Costs
           • Capex
           • Technology R&D
           • Opex
           • Ongoing R&D
           • Small overhead staff
     – Reasons to choose this model
           • If R&D is yielding multiple technologies that could be licensed to numerous bio-
              chemical/biofuel producers (potentially beyond hydrogen)
           • If projected costs of facility construction outweigh projected profitability
     – Pros
           • Closest to existing researcher core competencies
           • Shortest development pipeline
           • Lightest asset and capital intensity
     – Cons
           • Least value add; lowest potential to capture value
     – Complementary assets/technologies
           • Knowledge of developments in related technologies. Specialized; requires research
              partnerships.
Interview Notes
Dr. George Sverdrup
Technology Manager — Hydrogen, Fuel Cells, and Infrastructure Technologies
National Renewable Energy Laboratory

• NREL has a couple of projects on bio-based hydrogen production
• Further resources on development of hydrogen technology and infrastructure
         – See Posture Plan on DOE Hydrogen project page; describes different strategies for the national
            program.
         – See also multi-year RD&D plan – covers multiple pathways (search on “hydrogen multi-year plan”)
         – Could call Pin Ching Maness – leads bacterial projects at NREL – 303 384 6114 ... she might
            have opinion on how yeast stacks up to bacterial
• Gasification of biomass for hydrogen
         – Thought to be applicable to centralized production (e.g., 50K kg/year of H2), but not small distributed
            production
         – With technical advances, could get H2 production below $2.50/kg
         – Most biomass gasification research has been directed towards syngas combustion for power... 2-3
            projects country-wide on gasification for hydrogen production.
         – Seen as more near-term, but only when we it becomes necessary to produce hydrogen
            centrally and distribute (years off)
• Bacterial fermentation
         – Feedstock cost very high; hard to meet $2-3/kg cost. Largely driven by feedstock costs.
         – If could get organisms that could process cellulose, that might get around this cost.
         – So, NREL looking at different cocktails of bacteria.
         – More directed at distributed rather than centralized production.
         – One big issue: fermentation processes create multiple byproducts; molar yield of hydrogen
            nowhere close to theoretical maximum
Interview Notes
Dr. George Sverdrup (CONT’D)
Technology Manager — Hydrogen, Fuel Cells, and Infrastructure Technologies
National Renewable Energy Laboratory

• How concerned about storage and distribution issues?
       – Quite; DOE focusing an entire effort on delivery and storage.
       – Looking at pipeline, compressed storage, by road, liquification over the road. Cost of distributing may
          overwhelm production.
       – Seems likely that these will be overcome. Local, distributed generation would cut down
          transportation costs greatly... but still need storage and compression technologies.
• How confident in evolution of market towards transportation?
       – Quite
       – Hydrogen has great promise to meet transportation needs
       – H2 will probably be used in other markets before transportation gets going: backup power generation
          for telecommunications; stationary uses (natural gas reformation for fuel cell use now)
       – Many companies are investing now in hydrogen products, but given cash burn rate, question of how
          many will last
Interview Notes
Mr. William Baade
Market Expert — Hydrogen and Bioengineered Organism
Air Products
Key Points:

• Before you will be able to get to the market you need to pass four steps:
              – Prove the process
              – Pilot Plant
              – Commercial Demo
              – Acquire the Market

• The issue with natural processes to obtain H2 is the pressure.
               – Most of applications use H2 at a pressure of 800psi.
               – From gasification H2 comes out at 400psi, making it very easy to bring it to 800psi
               – If you have to start form atmosphere pressure the process is long and very expensive in term
                  of energy needed, as it needs many steps due to the small dimension of the H2 molecule
               – Some uses for low pressure H2 are related to food and steel processing, but those are very
                  small markets
               – To get in the Ammonia and Ethanol market you need to take the H2 at high pressures

• The production costs with the standard process at 800psi are :
               – 3$ per 1000 cubic foots that is approximately 1.2$ per Kg
               – On that you have to add 1-3$ per 1000 cubic foots of capital expenses (depending on the size
                  and efficiency of the plant)
               – Liquid H2 goes at 10-15$ per Kg
               – A world class plant produce 100 Millions Cubic Foots per day
Interview Notes
Mr. Jerald A. Cole
Chief Technology Officer
Hydrogen Ventures

• Overall Market:
– It is very difficult to estimate the overall size of H2 market, because the captive H2 market (e.g. refinery) is
  approximately 8-10 times larger.
– It is very difficult to get into the market for a couple reasons: 1) dominant players are willing to sell H2 for loss,
  since most of their users purchase a package of gases; 2) H2 users are concerning about the quality of H2 and
  reluctant to switch to unfamiliar suppliers.

• Fuel Cell market is emerging.
– A couple of niche markets which fuel cell is getting into: 1) Jadoo Power Systems, based in Folsom, Calif., has
  developed hydrogen fuel cells for portable, professional video cameras that it claims are cheaper and last
  longer than conventional batteries. 2) H2 Fuel Cell is an attracting energy source for luxury vacation homes
  located in remote area (45,000 of them are built last year, rich people are looking for all different ways to power
  up these vacation homes, solar cells is another option for them).
– Still people are waiting for a major breakthrough in Fuel Cell technique to reduce the cost.
– H2 used for Fuel Cell needs to meet five 9 standard, thus very expensive.

• Other growing H2 market:
– H2 combustion engines (e.g. BMW is testing hydrogen combustion 7-series.).
Interview Notes
Mr. John Trbovich
Principal
OnPoint Technologies

•   Market Insight
-   “future” uses of H2 will probably not develop into a viable market for at least 10 to 15 years
-   fuel cell is at this point the most likely use of H2 in energy generation.
-   major technical hurdles in H2 transportation, storage, and fuel cell must be overcome before the full potential of
    H2 can be realized

• Investment Insight
– their venture fund has funded projects out of the university before, and they all share the following
  characteristics:
          – Technology/process is usually at its earliest stage
          – The team that developed the technology is a major factor in considering whether to fund it or not
– With regard to this particular technology, the bottom line is whether we can make a case for the industrial use
  of hydrogen generated through this technology for the period of time before other “future” uses of H2 develops
Interview Notes
Dr. Andrew Murray
Professor
Department of Molecular and Cellular Biology, Harvard University

• Technological Insight
- there are significant technical hurdles yet to be overcome in the full development of the technology according to
  the plan outlined by the Silvers group.
- metabolic engineering is an emerging field with many uncertainties; therefore, the developmental timeline given
  by the Silvers’ group should be taken with a grain of salt.
- scalability of the process needs to be experimentally demonstrated
- it would be worthwhile to consider how much scientific resources (i.e number of graduate students, amount of
  funding etc.) the Silvers group intend to devote to the further development of this technology. In light the of the
  significant technical hurdles that they must overcome, full time engagement of at least a few graduate students
  and/or post-docs are necessary.

• Bottom Line
– The technical feasibility of the process is in no way guaranteed and therefore monitoring of the progress of the
  development team is of crucial importance if money is to be invested.
– Significant investment should not be made until more data is provided to demonstrate the feasibility of the
  technology as proposed.
Interview Notes
Wal van Lierop – 16 November 2007
President & CEO
Chrysalix Energy Venture Capital, Vancouver, Canada
Hydrogen market overview

• Key take-away: hydrogen market for industrial uses is EXTREMELY TOUGH to enter. Market leaders such as
  Air Products and Praxair control the market, therefore even if a start-up company were to come up with a new
  process for cheaper hydrogen production, the major industrial clients (e.g. refineries) would still rely on leaders
  such as Air Products and Praxair.

Indeed, not only is hydrogen a limited cost item for these industrial customers, BUT hydrogen is critical to their
   operations so they would prefer paying a little more but being able to rely on a stable, well-established
   company for their hydrogen supply and not on a brand new start-up.

• Industrial use is typically good for on-site hydrogen production: steel used in automotive industry for instance,
  undergoes heat treatment in annealing furnaces that use hydrogen. BUT same problem as described above
  regarding the difficulty of penetrating the market.

• Industrial customers care about low cost hydrogen solutions BUT reliability is also a number one concern

• Critical aspect for hydrogen start-up is great management team for execution in the industrial space

• Hydrogen fuel for vehicles will not happen within a 7-year timeframe so need to find alternative niches for
  hydrogen generation companies

• Would not invest in hydrogen companies whose only competency is to produce hydrogen, needs another asset
  (e.g. ethanol play, service to oil & gas industry) to be an attractive investment opportunity at this point in time
Interview Notes
Wal van Lierop – 16 November 2007 (continued)
President & CEO
Chrysalix Energy Venture Capital, Vancouver, Canada

Views on biological processes for hydrogen generation


• Problems of dealing with biomass as feedstock: availability and variations in quality of feedstock, and variations
  in quality of hydrogen gas being produced


• Could be niche markets for small-scale on-site hydrogen production using biomass: for instance, stand-by
  power generation systems using fuel cells with a biomass source nearby


• Could partner with Wal-Mart that started experimenting with fuel cells for indoor forklifts – could couple that with
  hydrogen from biomass, HOWEVER Wal-Mart would probably not pay anything for it and would only consider it
  as a free experiment


• Hydrogen production cost needs to be at or less than $2 per kg, otherwise there is no way to compete (e.g.
  electrolysis to generate hydrogen is too expensive)
Interview Notes
Mark Murphy
Vice President Finance
Praxair Asia, Inc.

• H2 production

- It calls itself supplemental provider to petroleum refinery, which is the major revenue source.
- Method: Steaming reforming.
        - Transportation: large production unit with pipeline network on site.
        - Capacity of a plant: 100 million standard cubic feet per day, while the refinery consumes 2-500 million
           standard cubic feet per day.
        - The price is influenced by the cost of feedstock, which is natural gas.
- Small electrolysis unit to produce hydrogen.
        - The hydrogen produced this way normally is packaged in high-pressure cylinder.
        - This segment is highly fragmented and has a lot of small providers.

• H2 market
– Grows considerably in general mainly because the US and Europe have tighter regulations on refinery, the US
  market especially due to its high sulfur crude.

• Price

– The market price will determine how to build production, storage place and distribution.
Interview Notes
Barry Stevens
President
National Hydrogen Fund
• Cost
- Capital investment and development cost.
- Feedstock: biomass. What if any of these cost goes up by 2 to 3 fold.
- Energy demand: heat? Electricity?
- Emission: How to capture H2? Carbon waste?
- How long will it take to put into mass production? 4 stages to go (proof of principle, proof of performance, true
  demonstration and mass production).
- Acceptable cost is $1.5-2 dollar per equivalent gallon of gas energy.

• Market
- H2 as energy source is a very attractive market and will happen eventually if the government is more concerned about
  environment.
- The H2 market for energy use is estimated to be 70 million billion BTU and the power need will increase by 66% in
  2025. Right now only 6.2 million are produced by renewable energy. The markets he is looking at are infrastructure
  (grid-connected power source) and transportation (vehicles). There are enormous breakthroughs in technologies
  related to these markets, but the costs are still relatively high comparing to coal. However, H2 is able to substitute
  fossil energy source if there is a strong pressure from the top to adopt it.

• Business/Operations
– When he looks at a business opportunity, he also looks at the team (inventors if they are to commercialize the
  technology.) apart from the technology itself.
– The price of a product is normally charged at 3 times its production cost.
– It always at least takes 3 years for a technology from idea to mass production.

						
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