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MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identication
Product Name Part Number Product Use Series Name Manufacturer
CONTRAD 70 81911 For In Vitro Diagnostic Use. See product literature for details. ACCESS® Beckman Coulter, Inc. 4300 Harbor Blvd. Fullerton, CA 92835-3100, U.S.A. Beckman Coulter Ireland Inc. Mervue Business Park Mervue, Galway, Ireland 353 91 774068 Refer to attached list, Document ID: 472050, for local distributor and emergency phone numbers.
Doc. ID: 81911-75 AD . Revised (year/month/day) 2008/03/24
EC REP Address
Distributor and Emergency Phone No.
Section 2 Hazards Identication
White; Translucent; Liquid; Mild odor Nonammable aqueous solution. Corrosive; eye, skin burns, severe respiratory tract irritant.
Physical Hazards Potential Health Effects Summary Potential Environmental Effects Product Hazard Classications
No physical hazards were determined from a review of available literature. Exposure may cause irritation or burns to respiratory tract, skin, and eyes. Corrosive effects may be delayed. See Section 11 Toxicological Information for more detailed health information. Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Meets Hazardous Criteria for Preparation/Mixture EU:
©2008 Beckman Coulter, Inc. Global MSDS – English
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Section 3 Composition and Information on Ingredients
Hazardous Ingredients: Chemical Name
Hazard Classication of Pure Ingredients CAS # 1310-58-3 EINECS # 2151813 % by wt. < 5% EU C;R22-35 WHMIS D1B; E US OSHA Corrosive Toxic Water-Reactive
See Section 15 Regulatory Information for additional information on hazard classications. See Section 16 for Risk Phrases and WHMIS Classication Description.
Section 4 First Aid Measures
Inhalation Eye Contact
If product is inhaled, move exposed individual to fresh air. If individual is not breathing, begin articial respiration immediately and obtain medical attention. If product enters eyes, wash eyes gently under running water for 15 minutes or longer, making sure that the eyelids are held open. If pain or irritation occur, obtain medical attention. In case of skin contact, ush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. If pain or irritation occur, obtain medical attention. If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical attention.
Section 5 Fire Fighting Measures
Flammable Properties Extinguishing Media Special Fire and Explosion Hazards Hazardous Combustion Products Protective Equipment for Fireghters
Nonammable aqueous solution. Use extinguishing media suitable for surrounding re. None identied. Due to the composition and volume of this product, combustion products generated from it are not expected to present a signicant hazard. Self-contained breathing apparatus is recommended for reghters in all chemical re situations.
Section 6 Accidental Release Measures
Personal Precautions Spill and Leak Procedures Environmental Precautions
Avoid skin contact. Use good laboratory procedures. Absorb spilled material with an appropriate inert, non-ammable absorbent and dispose according to local regulations. Contain spill to prevent migration.
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Section 7 Handling and Storage
Handling Precautions Recommended Storage Conditions
Avoid inhaling, ingesting, and contact with eyes and skin. Keep away from incompatible material (see Section 10). To maintain efcacy, store according to the instructions in the product labeling.
Section 8 Exposure Controls and Personal Protection
Exposure Limits US OSHA: ACGIH:
2 mg/m3 Ceiling None established None established None established No special engineering controls are required. Use with good general ventilation. Under normal conditions, the use of this product should not require respiratory protection. If overexposure should occur and ventilation is not adequate to maintain airborne concentrations at acceptable levels, the use of respiratory protection should be evaluated by a qualied professional. Safety glasses or chemical goggles should be worn to prevent eye contact. Impervious gloves, such as Nitrile or equivalent, should be worn to prevent skin contact.
DFG MAK: NIOSH Japan Engineering Controls Respiratory Protection
Eye Protection Skin Protection
Section 9 Physical and Chemical Properties
Physical State Color Transparency Odor Odor Threshold pH Freezing Point Boiling Point Flash Point Evaporation Rate Flammability (Solid, Gas) Flammable Limits
Liquid White Translucent Mild odor Not applicable 13 Not available >212°C (413.6°F) Not applicable Not available Not applicable Not applicable
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Section 9 Physical and Chemical Properties (Continued)
Vapor Pressure Vapor Density Specic Gravity Solubility Water Organic Coefcient of Water/Oil Distribution Autoignition Temp. Decomposition Temperature Percent Volatiles
Miscible Not available Not available Not applicable Not available Not applicable Not available Not available 1.06 @20°C
Section 10 Stability and Reactivity
Stability Hazardous Incompatibilities
Stable under normal temperatures and pressures. Strong acids Strong bases Strong oxidizers When stored as labeled, no known hazardous decomposition products are formed during the shelf-life of this product. Keep away from incompatible material.
Hazardous Decomposition Products Conditions to Avoid
Section 11 Toxicological Information
Toxicity Data for Hazardous Ingredients
Oral LD50 Rat: 214 mg/kg The most likely routes of exposure are skin, eye contact and inhalation. Inhalation of dilute alkaline mists may result in irritation of mucous membranes with sore throat, coughing, difculty in breathing; intense exposure, the lungs may ll with uid. Contact with dilute solutions may cause irritation or skin injury with redness, ssures and white patches. Eye contact may result in severe burns with possible loss of sight, irritation of eyes and eyelids, pain and intense watering. Ingestion may result in burns to the mouth, throat and stomach with burning sensations in the mouth, abdominal pain, vomiting, diarrhea, shock and loss of consciousness. Although its concentration in the product is low, potassium hydroxide is toxic by ingestion.
Primary Routes of Exposure Potential Effects of Acute Exposure
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Section 11 Toxicological Information (Continued)
Potential Effects of Chronic Exposure
Repeated skin contact with dilute alkaline may cause irritation with redness and swelling or burns. Repeated eye contact may cause conjunctivitis with redness, swelling and watering or burns. Depending upon concentration, repeated ingestion may result in inammatory or ulcerative effects on the mouth with redness, swelling and sores in the mouth. Symptoms may include: coughing, headache, fatigue, nausea, vomiting, dizziness, blurred vision, red and watery eyes, abdominal pain and unconsciousness. No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA or 67/548/EEC Annex I. None identied. Individuals with eye and skin disorders may nd these conditions aggravated by exposure to this product.
Symptoms of Overexposure Carcinogenicity Other Effects Conditions Aggravated by Exposure
Section 12 Ecological Information
24 Hr LC50 Gambusia afnis: 80.0 mg/L No information available. No information available. No information available. No information available.
Biodegradability Bioaccumulation Mobility Other Adverse Effects
Section 13 Disposal Considerations
Dispose of waste product, unused product and contaminated packaging in compliance with federal, state and local regulations. If unsure of the applicable requirements, contact the authorities for information.
Section 14 Transport Information
Shipping Name UN/ID Number Packing Group Potassium Hydroxide Solution 1814 II 8 Corrosives None Not applicable 8L 8 Corrosive substances None
Hazard Class Subsidiary Risk Special Provisions IATA ERG Code
Hazard Class Subsidiary Risk
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Section 14 Transport Information (Continued)
Special Provisions Marine Pollutant None No ORM-D Consumer Commodity None DOT Exception 153.154(c) (US ground only) 154 8 Corrosive substances C5 None 1814 8 Corrosives None None 154
Hazard Class Subsidiary Risk Special Provisions NAERG Number
ADR Classication Classication Code/ Subsidiary Risk
PIN TDG Classication Subsidiary Risk Special Provisions NAERG Number
Section 15 Regulatory Information
US Federal and State Regulations SARA 313 CERCLA RG’s, 40 CFR 302.4 California Proposition 65 Massachusetts MSL New Jersey Dept. of Health RTK List Pennsylvania RTK EU Labeling Classication Classication
Corrosive No ingredients listed. Potassium Hydroxide is listed. No ingredients listed. Potassium Hydroxide is listed. Potassium Hydroxide is listed. Potassium Hydroxide is listed.
Risk and Safety Phrases
R34 Causes burns. S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
This product is exempt from WHMIS label and MSDS requirements. PIN: 1814
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Section 15 Regulatory Information (Continued)
Ingredients on Ingredient Disclosure List: Ingredients with unknown toxicological properties:
Potassium Hydroxide Product is exempt
Some hazardous ingredients listed in Section 15 are below OSHAs and WHMIS’ 1.0% w/w (0.1% for carcinogens) or EU’s ingredient specic concentrations required for reporting in Section 3.
Section 16 Other Information
Beckman Coulter Safety Rating
Flammability (Section V): 0 Health (Section XI): 3 Reactivity with Water (Section X): 0 Contact (Section VIII): 3 Code 0=none 1=slight 2=caution 3=severe
Revision Changes Risk Phrases and WHMIS Classication Description From Section 3
Reformatted Sections 2, 3, 5, 8, 9, 12, 15, and 16 per ANSI Z400.1-2004 Standard. R22 Harmful if swallowed. R35 Causes severe burns. D1B - Acute Dermal Toxicity D1B - Acute Inhalation Toxicity D1B - Acute Oral Toxicity E - Corrosive Material
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.