Application of Nanotechnology to Biomedical Studies

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					NHMRC FUNDED RESEARCH INVOLVING NANOTECHNOLOGY ISSUES 2000 - 2009
                                    2000              2001        2002       2003        2004           2005          2006          2007         2008          2009
Nanotechnology by CY
                                   $45,809        $140,380       $140,828   $381,845   $370,625      $745,625       $550,692     $1,230,023 $1,875,243      $3,528,998

Report Run: 19 Dec 2007/Updated 11 Apr 08/10 Aug 09
Source: Updated from NHMRC databases - RMIS/GMS - as at Aug 09

                                   2000-01        2001-02        2002-03    2003-04     2004-05       2005-06       2006-07       2007-08      2008-09        2009-10
Nanotechnology by FY
                                   $25,161        $210,794       $230,095   $382,539   $519,188      $713,035       $860,990     $1,387,771 $2,972,251      $2,736,663

Methodology: NHMRC Research funding datasets rely entirely on the information provided by the Chief Investigators through the application process. Decisions
on allocation to particular disease and health issue datasets are made subjectively by the NHMRC Evaluation and Reporting Section (supported by other internal
review mechanisms) based on the information provided. The key search parameters listed above form the basis of the coverage of this dataset. Lay descriptions,
where available have also been reviewed to support the allocation.

Keywords: nanotechnology, nano*, molecular scale, nanobiotechnology, nanoparticles, nanoscale, nano-scale, nanometer, nanometre, macromolecular,
nanoscience, nanosystem, nanostructures, nanoprojection, liposome, ultrafine, zeta potential, zeta potentia, fullerenes, quantum, micelles, microspheres,
colloidal,C60,fullerol, cyclodextrin, nanoengineering, metal oxide, nanosilver, zinc oxide, titanium oxide, titanium dioxide, silver, Ag+, Cryolite, dendrimers,
supramolecular, calixarene, Microelectrophoresis
Grant Types:Includes all grant types except IRIISS and equipment grants
Fields of Research: Review All - in particular Nanotechnology, Biotechnology
Status: Accepted, Approved, Payments can be made, Suspended, Terminated, Completed
Where: Start Year >= 2000
Pay Type: Calendar year budgets. Excludes claims. Excludes GST
Note: All figures shown are the cash amounts awarded to recipients in the calendar year
Data source: These data are sourced from the pre 2000 NHMRC Grants Management Systems (GMS) and post 1999 NHMRC Research Management
Information Systems (RMIS) grants databases.
NHMRC FUNDED RESEARCH INVOLVING NANOTECHNOLOGY ISSUES 2000 - 2009
Keywords: nanotechnology, nano*, molecular scale, nanobiotechnology, nanoparticle, nanoscale, nano-scale, nanometer, nanometre, macromolecular,
nanoscience, nanosystem, nanostructures, nanoprojection, liposome, ultrafine, zeta potential, zeta potentia, fullerenes, quantum, micelles, microspheres,
colloidal,C60,fullerol, cyclodextrin, nanoengineering, metal oxide, nanosilver, zinc oxide, titanium oxide, titanium dioxide, silver, Ag+, Cryolite, dendrimers,
supramolecular, calixarene, Microelectrophoresis
Report Run: 19 Dec 2007/Updated 11 Apr 08/10 Aug 09
Source: Updated from NHMRC databases - RMIS/GMS - as at Aug 09
Summary Notes
1. This dataset contains the details of all NHMRC funded research grants that have been identified as having a connection with Nanotechnology related
research issues through search of the Chief Investigator provided keyword and titles contained in the NHMRC research database. Relevance to the
research area in question may be either immediate or be a longer term perceived benefit. This dataset was current as at 10 Aug 09 but is subject to
change over time.
Summary of Expenditure: Nanotechnology
       2000                    $45,809 Actual Expenditure          1 grant                            NHMRC Research Funding 2000 - 2009
       2001                   $140,380 Actual Expenditure          1 grant                                   Nanotechnology Issues
       2002                   $140,828 Actual Expenditure          1 grant
       2003                   $381,845 Actual Expenditure          3 grants                2008
       2004                   $370,625 Actual Expenditure          4 grants
       2005                   $745,625 Actual Expenditure          6 grants
                                                                                           2006
       2006                   $550,692 Actual Expenditure          5 grants
       2007                 $1,230,023 Actual Expenditure          11 grants
       2008                 $1,875,243 Actual Expenditure          16 grants               2004
       2009                 $3,528,998 Forecast Expenditure        23 grants
      Total                 $9,010,068 As at Dec 2009                                      2002
       2010                 $2,098,125 Forward commitments         14 grants
       2011                 $1,249,114 Forward commitments         8 grants                                                            Thousands
                                                                                           2000
       2011                   $417,050 Forward commitments         1 grant
       2011                    $98,650 Forward commitments         1 grant                      $0        $1,000     $2,000      $3,000       $4,000
       Total               $12,873,007 Incl out years
2. Forward commitments funding data for out-years (ie beyond 2009) is subject to change when new grants are awarded in subsequent years


 Grant Id                 CIA                         Grant Type          Grant Subtype            Scientific Title     Simplified Title Admin Institutution
    980595    A/Pr Leonard Kritharides      NHMRC Project Grant                                                      Cyclodextrin-mediated sterol removal from
                                                                                                                                        Heart Research Institute
                                                                     Standard Project Grant Cyclodextrins and physiological sterol removal from macrophages macrophages
    143090    Prof Istvan Toth              NHMRC Project Grant                                                      Targeted DNA ofUniversity of Queensland
                                                                                                                                         oligonucleotides with therapeutic potential
                                                                     Standard Project Grant Charged lipophilic dendrimers: Deliverydelivery
    254504    Dr Livia C Hool               NHMRC Project Grant                             How does                 Ca2+ channel function in cardiac muscle cells during lowered oxy
                                                                                                                                        function in cardiac myocytes?
                                                                     Priming Grant (New Investigator) oxygen regulate Ca2+ channel University of Western Australia
    254727    Dr Nadezda Urosevic           NHMRC Project Grant      Development Grant                               Flavivirus-specificUniversity compound
                                                                                                                                         antivirus of factor Mrasal
                                                                                            Synthesis and purification of flavivirus-specific antiviral Western Australia
    279408    Prof Jonathan Golledge        NHMRC Project Grant                                                      in protecting the diabetic aorta from aneurysm formation
                                                                                                                                        and diabetes
                                                                     Standard Project Grant Role of osteoprotegerin Artery weakening James Cook University
    311216    Prof Istvan Toth              NHMRC Project Grant      Development Grant                               Oligonucleotide Delivery
                                                                                                                                        University of Queensland
                                                                                            Biological membrane transporters: Delivery of an oligonucleotide inhibitor of vascular end
    316949    Dr JOSEPH G ALTIN             NHMRC Project Grant                                                      A NOVEL APPROACH TO DENDRITIC CELLS IN DENDRITIC
                                                                                                                                        Australian TARGETING DNA
                                                                     Standard Project Grant A NOVEL APPROACH FOR TARGETING DNA FORNational University TOVIVO FOR V
   334098   Prof Michael Abramson NHMRC Project Grant                                                           What effects do tinyMonash University
                                                              Standard Project Grant Cardiorespiratory effects of ultrafine particlesparticles have on the heart and lungs?
   359293   Prof Paul Mulvaney         NHMRC Project Grant    Development Grant                                 Q-Sand (TM) Whispering System For Ultrasensitive
                                                                                                                                    University of Melbourne
                                                                                     Q-Sand (TM): Whispering Gallery Mode DetectionGallery Mode Technology and Label F
   379600   Prof Jonathan Golledge NHMRC Project Grant                                                          Drug therapy for aortic aneurysm
                                                                                                                                     aortic Cook University
                                                              Standard Project Grant Interaction of Angiotensin II and PPARg inJames aneurysm formation
   409918   A/Pr Sherry y y WU         SCHOLARSHIP                                   Liposomal delivery of RNA inhibitory nucleotides forinhibitory nucleotides for treatment of
                                                              Public Health Postgraduate Scholarship                                University treatment of cervical cancer
                                                                                                                Liposomal delivery of RNA of Queensland
   433613   A/Pr Joan K Heath          NHMRC Project Grant                                                      Killing colorectal cancer cells with for to kill drug-loaded
                                                                                                                                    Ludwig Institute targeted colorectal cancer cells
                                                              Standard Project Grant Development of drug-loaded antibody-targeted nanoparticles Cancer Research nanopart
   433624   Dr Andrew HA Clayton       NHMRC Project Grant                                                      Signalling dynamics in living cells for Cancer Research
                                                              Standard Project Grant Single Molecule Cell Biology                   Ludwig Institute
   451903   Dr Natasha M Rogers        SCHOLARSHIP                                   Specific targeting of dendritic cells with tolerogenic liposomes inHospital
                                                              Medical Postgraduate Scholarship                                      of dendritic cells with allotransplantation
                                                                                                                Specific targeting The Queen Elizabeth tolerogenic liposomes in a
   455890   Dr Nigel AJ McMillan       NHMRC Project Grant                                                      Delivery of gene-silencing nucleotides
                                                                                                                                    University of Queensland
                                                              Standard Project Grant Non-viral vectors for targeted delivery of RNAi nucleotides to cervical cancers
   455968   Prof Boris Martinac        NHMRC Project Grant                                                      Bacterial Mechanosensitive of as Nanodevices in Liposome Syst
                                                                                                                                    University Channels as Nanodevices
                                                              Standard Project Grant Development of Bacterial Mechanosensitive Channels Queensland
   456150   Prof Mark AF Kendall       NHMRC Project Grant                                                      MPM biological interactions of Queensland delivery with micro-na
                                                                                                                                    University following drug
                                                              Standard Project Grant MPM non-invasive imaging of non-invasive imaging of biological interactions following dru
   456314   Miss Susan HUA             SCHOLARSHIP                                   Peripheral mechanisms Peripheral mechanisms of analgesiacell adhesion
                                                              Biomedical Postgraduate Scholarship                                   University of Queensland
                                                                                                                of analgesia and the involvement of and the involvement of cell
   471512   Dr Ross W Stephens         NHMRC Project Grants Development Grant                                   Novel for molecular probes National University
                                                                                                                                    Australian in diagnostic imaging
                                                                                     Novel nanoparticle compositesnanoparticles for molecular probes in diagnostic imaging
   472665   Prof Karlheinz Peter       NHMRC Project Grant    Development Grant                                 MRI-nanoparticles for non-invasive diagnosis of
                                                                                                                                    Baker Heart diagnosis of vascular diseases in m
                                                                                     Novel single-chain antibody-targeted nanoparticles for Research Institutevascular disease
   472668                                                      AWARDS
            Dr Christoph E HagemeyerCAREER DEVELOPMENTIndustry CDA                                              Nanoparticles fo diagnosis forResearch Institute
                                                                                                                                    Baker Heart diagnosis of vascular diseases
                                                                                     Novel Single-chain antibody-targeted nanoparticles of vascular diseases
   479505   A/Pr Wei Duan              NHMRC Project Grant                                                      A novel tumour-targeting Universitydelivery treatment the treatm
                                                                                                                                    Deakin lipid drug
                                                              Standard Project Grant A novel tumour-targeting nanoliposome drug delivery system for thesystem for of maligna
   490908   Prof Magdalena Plebanski NHMRC Project Grant                                                        Understanding by nanoparticles
                                                                                                                                    Monash University
                                                              Standard Project Grant Inhibition of allergic airway inflammationinhibition of allergic pulmonary inflammation by sp
   491181   A/Pr Christopher JH Porter NHMRC Project Grant                                                      The importance of by cell surface receptors: A novel mechanism
                                                                                                                                    Monash University
                                                              Standard Project Grant Recognition of macromolecular complexes intestinal 'scavenger' receptors in the absorpti
   511303   Prof Hans J Griesser       NHMRC Project Grant                                                      Nano-Oncology TO IMPROVE TUMOUR DELIVERY OF CHEM
                                                              Standard Project Grant IMMUNOTARGETED NANOPARTICLES University of South Australia
   525456   Dr Andrei V Rode           NHMRC Project Grant                           Optical vortices for trappingcleaning from Australian National University
                                                              Priming Grant (New Investigator)                                      nanoparticle contamination
                                                                                                                Air and guiding nanoparticles in air
   568782   A/Pr Maria Kavallaris      NHMRC Project Grant                                                      Targeting cancer University of New South Wales
                                                                                                                                    genes to improve cancer
                                                              Standard Project Grant Improving cancer therapy: nanoparticle delivery of siRNA to therapy cells
   569525   Prof Julie H Campbell      NHMRC Project Grant                                                      Targeted delivery University of Queensland nanoparticles
                                                                                                                                    of anti-restenotic agents
                                                              Standard Project Grant Antibody-directed delivery of anti-restenotic agents using inorganic using antibodies and n
   579705   Mr Justin L Bourke         SCHOLARSHIP                                   Design and use             Design and use of in neural stem cell network formation
                                                                                                                                    Monash University
                                                              Biomedical Postgraduate Scholarship of conductive biopolymers conductive biopolymers in neural stem cell net
   546238   A/Pr James R Friend        NHMRC Project Grant    Development Grant                                 The NanoNautilus Successful Treatment of Strokes and Other Ce
                                                                                                                                     : A Breakthrough
                                                                                     The NanoNautilus : A Breakthrough in theMonash University in the Successful Treatment
   569258   Dr Mark A Baker            NHMRC Project Grant                           Identification and characterisation of phosphorylation events taking place during human s
                                                              Priming Grant (New Investigator)                                      University of Newcastle
                                                                                                                Identification of phosphorylation events taking place during huma
   569694   Prof Rod F Minchin         NHMRC Project Grant                                                      Toxicology          University
                                                              Standard Project Grant The Toxicology of Nanomaterials of Nanomaterialsof Queensland
   569726   Prof Mark AF Kendall       NHMRC Project Grant                                                      Nanopatch immunisation against influenza
                                                                                                                                    University of Queensland
                                                              Standard Project Grant Nanopatch immunisation against pandemic influenza: improved immune responses at a r
   572734   Prof Fiona M Wood          NHMRC Project Grant    Development Grant                                  nano-membrane promote faster wound wound healing
                                                                                                                                     dressings to promote healing
                                                                                     Pre-clinical evaluation ofNovel dresings to University of Western Australia
   631720   Prof Mark AF Kendall                                                     H1N1 Nanopatch immunisation against pandemic Novelagainst pandemic Novel A (H1N1
                                       NHMRC Strategic Awards Urgent Research - Pandemic Influenza                                  immunisation A (H1N1)
                                                                                                                H1N1 Nanopatch University of Queenslandinfluenza virus 09: pot


Note: 254504 and 279408 is included because the CIA identified it as having some connection with Nanotechnology through an NHMRC Survey in 2005. On the basis that 279408 i
                    Start
 State   App Year           1998      1999      2000       2001     2002      2003      2004     2005     2006      2007       2008
                    Year
NSW        1997     1998    $53,280   $51,530   $45,809
QLD        2000     2001                                  $140,380 $140,828   $140,828
WA         2002     2003                                                      $168,517 $153,500 $153,500
WA         2002     2003                                                       $72,500 $67,500
QLD        2003     2004                                                                $99,750 $99,750 $99,750
QLD        2003     2004                                                                $49,875 $49,875
ACT        2004     2005                                                                        $146,750 $141,750   $141,750
            VIC          2004       2005                                                                              $168,000 $143,000    $158,250
            VIC          2004       2005                                                                              $127,750
            QLD          2005       2006                                                                                       $139,375    $142,575   $145,448
            QLD          2005       2006                                                                                        $26,817     $27,563    $28,067
            VIC          2006       2007                                                                                                   $167,000   $171,157
            VIC          2006       2007                                                                                                    $93,500    $95,993
            SA           2006       2007                                                                                                    $31,422    $32,003
            QLD          2006       2007                                                                                                   $136,050   $181,571
            QLD          2006       2007                                                                                                   $164,000   $167,286
            QLD          2006       2007                                                                                                   $140,350   $132,828
            QLD          2006       2007                                                                                                    $27,563    $28,067
            ACT          2007       2008                                                                                                              $113,629
            VIC          2007       2008                                                                                                              $102,899
            VIC          2007       2008                                                                                                               $92,500
            VIC          2007       2008                                                                                                              $105,590
            VIC          2007       2008                                                                                                              $176,340
            VIC          2007       2008                                                                                                              $129,985
            SA           2007       2008                                                                                                              $171,880
            ACT          2008       2009
            NSW          2008       2009
            QLD          2008       2009
            VIC          2008       2009
            VIC          2008       2009
            NSW          2008       2009
            QLD          2008       2009
            QLD          2008       2009
            WA           2008       2009
            QLD          2009       2009
                                                                            $45,809 $140,380 $140,828 $381,845 $370,625 $745,625 $550,692 $1,230,023 $1,875,243
                                                                               1         1          1          3          4 6       5         11         16
vey in 2005. On the basis that 279408 is included, similar work by the same researcher (Golledge) has also been included.
                                                     Broad        Field Of Research Research Research Research
2009   2010   2011   2012   2013   Total
                                               Research Area Research            KW 1        KW 2          KW 3          KW 4
                                    $150,619   Basic Science                  CHOLESTEROL 7-KETOCHOLESTEROL MACROPHAGE
                                                                                                       CYCLODEXTRIN
                                                                 Cardiology (incl. Cardiovascular Diseases)
                                    $422,036   Basic Science                  Charged dendritic Delivery ipophilic dendrimers
                                                                                           and systems
                                                                 Pharmaceutical SciencesDrug Pharmacy  L             Oligonucleotide delivery
                                    $475,517   Basic Science                  calcium channels
                                                                                          hypoxia      mitochondriareactive oxygen species
                                                                 Cardiology (incl. Cardiovascular Diseases)
                                    $140,000                     Medical Virology         baculovirus protein expression system
                                               Clinical Medicine and Science antiviral compounds                     liposome
                                                                                                       flaviviurs encephalitis encapsulation
                                    $299,250                     Surgery                  diabetes mellitus
                                               Clinical Medicine and Science aortic aneurysm           osteoprotegerin
                                     $99,750   Basic Science                  Charged dendritic Delivery rug
                                                                                           and systems D
                                                                 Pharmaceutical SciencesDrug Pharmacy DesignLipophilic dendrimers
                                    $430,250   Basic Science                  Cancer      DNA vaccine
                                                                 Tumour Immunologyimmunotherapy Dendritic cells      Liposomes
                                                                 $469,250   Public Health                  Air pollution Health Health andstudies
                                                                                                                                        Panel Safety
                                                                                              Environmental and Occupationalrisk assessment Ultrafine particles
                                                                 $127,750                     Aged Care Nursing                         N
                                                                            Clinical Medicine and Science Diagnostics Microspheres anotechnology     Quantum Dots
                                                                 $427,398                     Surgery                     drug          p
                                                                            Clinical Medicine and Science aortic aneurysm targetingathogenesis
  $14,344                                                         $96,791                     Pharmaceutical SciencesDelivery of siRNA
                                                                                                                           and          Gene
                                                                            Clinical Medicine and Science Cervical Cancer Pharmacy deliveryiposome   L
 $174,990                                                        $513,147   Basic Science                  anti-cancer drugs
                                                                                                                          antibody
                                                                                              Therapies and Therapeutic Technology      drug deliverymouse models of metastasis
  $98,117                                                        $287,610   Basic Science                  biochemistrybiotechnologypidermal growth factor receptor
                                                                                              Analytical Biochemistry                   e            quantum dots
  $32,628                                                         $96,053   Basic Science                  Dendritic cells
                                                                                              Transplantation Immunology  Liposomes Tolerance Transplantation
  $98,117                                                        $415,738   Basic Science                  Cancer         RNA
                                                                                              Oncology and Carcinogenesis interference               gene
                                                                                                                                        cervical cancer delivery
 $171,056                                                        $502,342   Basic Science                                 Ion channelsLipid bilayers
                                                                                              Biophysics Electron microscopy                         Patch clamping
 $130,434                                                        $403,612   Basic Science                  Epidermis Immunoregulation
                                                                                              Cellular Immunology                                    Skin cell
                                                                                                                                        Non-invasive imagingimmunogy
                                                                  $55,630   Basic Science                  AntinociceptionCell
                                                                                              Peripheral Nervous System adhesion        InflammationLiposomes
   $57,088                                                       $170,717   Basic Science                  Diagnostic imaging
                                                                                                                          Molecular NanoparticleNuclear medicine
                                                                                              Radiotherapy and Nuclear Medicineprobes                 radiolabelling
  $357,899                                                       $460,798                     Cardiology (incl. Cardiovascular Diseases)
                                                                                                                          Activated Dendrimer Single-chain antibodies
                                                                            Clinical Medicine and Science Activated monocytes platelets
   $94,250    $94,250    $94,250                                 $375,250                     CLINICAL SCIENCES Antherosclerosis        Cardiovascular disease prevention
                                                                            Clinical Medicine and Science Cardiology (incl. Cardiovascular Diseases) Cardiovascular risk
  $168,157 $168,157                                              $441,904   Basic Science     Surgery                                   n
                                                                                                           drug deliverydrug targetingeurosurgery    pharmaceutics
  $180,157 $180,157                                              $536,654                     Allergy
                                                                            Clinical Medicine and Science Allergic asthma                            Nanoparticle
                                                                                                                          Dendritic cellLung homeostasis
  $132,825 $132,825                                              $395,635   Basic Science                  Drug absorption Pharmacy
                                                                                                                           and
                                                                                              Pharmaceutical Sciencesdietary fat drug transport      epithelial transport
  $176,985 $182,090                                              $530,955   Basic Science                  BiomaterialsCancer
                                                                                              Biotechnology not elsewhere classified                 Monoclonal antibody
                                                                                                                                        Drug targeting
  $181,075 $170,875 $140,275                                     $492,225   Basic Science                  Air Techniques Occupational hazzards nanotechnology
                                                                                                                                        Optical trapping of nanoparticles in for
                                                                                              Instruments andpurification from nanomaterials inTrapping nanoparticlesair to
  $189,500 $209,900 $199,700                                     $599,100   Basic Science                  drug sensitivity
                                                                                              Oncology and Carcinogenesisnanoparticles siRNA solid tumours
  $107,050 $107,050 $107,050                                     $321,150   Basic Science                  anti-restenosis therapy drug
                                                                                                                          cardiovascular disease
                                                                                              Cardiology (incl. Cardiovascular Diseases) deliverydrug targeting
   $22,677    $22,677    $11,339                                  $56,693   Clinical Medicine and Science Autologous Neural Stem Cell Implantation
                                                                                              Neurosciences not elsewhere classified
                                                                                                                          ElectroactiveFluorescence Imaging and Image Analysi
                                                                                                                                         Biopolymer Nanobiotechnology
                                                                                                                                                     Design
  $187,213                                                       $187,213                     Surgery                     endoscopic endovascular technology
                                                                            Clinical Medicine and Science cardiovascular disease surgery             neurosurgery
   $91,750    $91,750    $91,750                                 $275,250   Basic Science     Reproduction                PhosphoproteomicsCapacitation phosphorylation
                                                                                                           Nano-flow LC-MS/MS           Sperm        Tyrosine
  $417,050 $481,358 $437,450        $417,050     $98,650       $1,851,558   Basic Science                  Pharmacokinetics
                                                                                                                          Pharmacology - toxicology
                                                                                              Toxicology (incl. Clinical Toxicology) Toxicology
  $167,300 $167,300 $167,300                                     $501,900   Basic Science                  Immunisation   Influenza
                                                                                              Humoral Immunology and Immunochemistry                 Topical
                                                                                                                                        Skin Immunology drug delivery
  $188,600                                                       $188,600                     Dermatologynano-membranes dressings healing
                                                                            Clinical Medicine and Science                 wound         wound
   $89,736    $89,736                                            $179,472                     Medical Virology
                                                                            Clinical Medicine and Science H1N1
$3,528,998 $2,098,125 $1,249,114   $417,050    $98,650       $12,977,817
    23         14          8          1                  1
             Research Health KW Health KW Health KW Health KW Health                Application     Unit
               KW 5             1           2          3             4       KW 5     Status       Status
            EFFLUX                                                                               Payments can be made
                                                                                   Payments can be made
                                     Choroidal Neovascularisation DiseaseGene Therapy
Oligonucleotide delivery Anti Angiogenesis                     E
                                                  Drug Delivery ye                               Payments can be made
                                                                                   Payments can be made
                                     cardiac      ion channel dysfunction
reactive oxygen species cardiac arrhythmia ischemia                                              Payments can be made
                                                                                   Payments can be made
            protein purification                                                                 Payments can be made
                                                                                   Payments can be made
                                     diabetes (type
                                                  therapeutic target
                          abdominal aortic aneurysm 2)         vascular disease                  Payments can be made
                                                                                   Payments can be made
            Oligonucleotide delivery                                                             Payments can be made
                                                                                   Payments can be made
                          Cancer
            Targeting delivery of DNA             Gene therapy             Vaccine Payments can be made
                                     Cancer immunotherapy Infectious disease                     Payments can be made
Ultrafine particles                     Coronary artery disease Lung function assessment
                                                      Heart rate variability
                          Chronic obstructive pulmonary disease                                               Payments can be made
                                                                                               Payments can be made
             Whispering Gallery Modes                                                                         Payments can be made
                                                                                               Payments can be made
                                        pathogenic mechanisms vascular disease
                          abdominal aortic aneurysm   treatment strategies                                    Payments can be made
                                                                                               Payments can be made
             RNA interference                                                                                 Payments can be made
                                                                                               Payments can be made
             nanotechology               metastasis colorectal cancer prevention and treatment cancer be made
                          colon cancercolorectal cancer                           immunotherapyPayments can Payments can be made
                                                                   drug delivery system design of
                          biological sciences
                                        cancer
             single molecule spectroscopy biology                  growth factors/receptors
                                                                                  ratio fluorescence spectroscopy
                                                      epithelial neoplasms/malignant                          Payments can be made
                                                                                               Payments can be made
Transplantation                                                                                               Payments can be made
                                                                                               Payments can be made
             nanoparticles              cervical
                          anti-tumour agents cancer                human papilloma virus/cervical carcinomamade
                                                      genetic therapy                          Payments can bePayments can be made
                          Cancer chemotherapy Lipids
             Protein structure          Drug delivery systems                                                 Payments can be made
                                                                                               Payments can be made
                           Delivery
             Topical DrugDrug Delivery                Non-invasive imagingimmunology Payments can be made
                                        Immunoregulation           Skin cell                                  Payments can be made
             Pain                                                                                             Payments can be made
                                                                                               Payments can be made
Nuclear medicine          Cancer                      Renal disease
                                        Cardiovascular disease Thrombosis                                     Payments can be made
                                                                                               Payments can be made
                          Atherosclerosis             Diagnosis                   Pulmonary Payments can be made
             Targeted nanoparticles Cardiovascular disease Magnetic resonance imaging          embolism       Payments can be made
                          Magnetic resonance imaging
             Endothelial dysfunction during antherosclerosis                                   Accepted       Payments can be made
pharmaceutics                                          systems                    pharmacotherapy
                          brain tumourdrug deliveryglioblastomapharmaceutical treatment                       Payments can be made
                                                                                               Payments can be made
             T cell                     Allergen      Asthma and Immunomodulation
                                                                    allergic the respiratory tract
                                                                                  Prevention Payments can beasthma
                                                                                               and             made
                          Airway inflammation induced inflammation in disease prevention treatment ofPayments can be made
             pharmaceuticsDiabetes      Drug delivery Nutrition    Obesity                     Payments can Payments can be made
                                                                                  pharmaceutical treatment be made
                          A             Cell death                 Novel therapeutic           Accepted
             Radiolabeling ntibody cancer therapy Mouse models of cancer Tumour specific targeting Payments can be made
                          Health and assessmentsNanomaterials Exposure tosafety
                                        Human and Environmental and health risk factor Health and Safety in Nanotechnology Industry
                                                                   Nanoparticles  Occupational
Trapping nanoparticles for toxicologyEnvironmental Impact of NanotechnologyNanomaterials                      Payments can be made
                                                                                               Payments can be made
                                                    gene
           targeted therapy cancerchemosensitization silencing     lung cancer                 Accepted       Payments can be made
                          atherosclerosis deliveryrestenosis restenosis after angioplasty
             nanotechnology             drug           systems                                 Accepted
                                                                                  targeted therapy            Payments can be made
             Neural Stem Cell Network Formation and Testing                                    Accepted       Payments can be made
             stroke                     cerebrovascular accident/stroke
                          cerebral embolism           neurosurgery                traumatic brain
                                                                                               Accepted       Accepted
                                                                   stroke/cerebral ischaemia injury/neurotrauma
             pp60c-SRC Hyperactivation                Immature sperm maturation
                                        Idiopathic infertility                    Sperm motility defects
                                                                   Male infertility            Accepted       Payments can be made
                                        pharmacology - toxicology
                          pharmacokinetics            toxicity                                 Accepted       Payments can be made
                          Alternative Drug delivery   Immune
             Vaccine Development Vaccination Strategies Responses                 Influenza Accepted
                                                                   Improvement of Vaccine Efficacy            Payments can be made
                                        chronic       skin repair
                          Cutaneous injuries and acute injuries                                Accepted       Payments can be made
                                                                                               Approved       No Unit Found
NHMRC FUNDED RESEARCH INVOLVING NANOTECHNOLOGY ISSUES 2000-01 to 2008-09
Keywords: nanotechnology, nano*, molecular scale, nanobiotechnology, nanoparticles, nanoscale, nano-scale, nanometer, nanometre, macromolecular,
nanoscience, nanosystem, nanostructures, nanoprojection, liposome, ultrafine, zeta potential, zeta potentia, fullerenes, quantum, micelles, microspheres,
colloidal,C60,fullerol, cyclodextrin, nanoengineering, metal oxide, nanosilver, zinc oxide, titanium oxide, titanium dioxide, silver, Ag+, Cryolite, dendrimers,
supramolecular, calixarene, Microelectrophoresis
Report Run: 19 Dec 2007/Updated 11 Apr 08/10 Aug 09
Source: Updated from NHMRC databases - RMIS/GMS - as at Aug 09
Summary Notes
1. This dataset contains the details of all NHMRC funded research grants that have been identified as having a connection with Nanotechnology related
research issues through search of the Chief Investigator provided keyword and titles contained in the NHMRC research database. Relevance to the
research area in question may be either immediate or be a longer term perceived benefit. This dataset was current as at 10 Aug 09 but is subject to
change over time.
Summary of Expenditure: Nanotechnology
  2000-01               $25,161 Actual Expenditure        1 grant
  2001-02              $210,794 Actual Expenditure        1 grant
  2002-03              $230,095 Actual Expenditure        2 grants
  2003-04              $382,539 Actual Expenditure        4 grants
  2004-05              $519,188 Actual Expenditure        6 grants
  2005-06              $713,035 Actual Expenditure        8 grants
  2006-07              $860,990 Actual Expenditure        10 grants
  2007-08            $1,387,771 Actual Expenditure        15 grants
  2008-09            $2,972,251 Actual Expenditure        25 grants
  2009-10            $2,736,663 Forecast Expenditure 24 grants
     Total         $10,038,487 As at Dec 2009
  2010-11            $1,673,618 Forward commitments 13 grants
  2011-12              $833,082 Forward commitments 8 grants
  2012-13              $257,850 Forward commitments 1 grant
  2013-14               $49,325 Forward commitments 1 grant
     Total         $12,852,362 Incl Out years
2. Forward commitments funding data for out-years (ie beyond 2009) is subject to change when new grants are awarded in subsequent years


 Grant Id             CIA                  Grant Type               Grant Subtype           Scientific Title        Simplified Title       Admin Institutution
   980595                        NHMRC Project Grants
            A/Pr Leonard Kritharides                                                                              Cyclodextrin-mediated sterol removal from macrophages
                                                                                                                                              Heart Research
                                                                 Standard Project Grant Cyclodextrins and physiological sterol removal from macrophages Institute
   143090   Prof Istvan Toth     NHMRC Project Grants                                                             Targeted DNA delivery University of therapeutic
                                                                 Standard Project Grant Charged lipophilic dendrimers: Delivery of oligonucleotides withQueensland potential
   254504   Dr Livia C Hool      NHMRC Project Grants                                   How does                  Ca2+ channel function in in cardiac myocytes? Australia
                                                                                                                                               cardiac muscle cells
                                                                 Priming Grant (New Investigator) oxygen regulate Ca2+ channel function University of Western during lowered oxygen ten
   254727   Dr Nadezda UrosevicNHMRC Project Grants              Development Grant                                 of flavivirus-specific antiviral factorof
                                                                                                                                              University Mrasal
                                                                                        Synthesis and purificationFlavivirus-specific antivirus compoundWestern Australia
   279408                        NHMRC Project Grants
            Prof Jonathan Golledge                                                                                Artery weakening and diabetes Cook University
                                                                                                                                              James
                                                                 Standard Project Grant Role of osteoprotegerin in protecting the diabetic aorta from aneurysm formation
  311216   Prof Istvan Toth     NHMRC Project Grants Development Grant                                  Oligonucleotide Delivery University of Queensland
                                                                            Biological membrane transporters: Delivery of an oligonucleotide inhibitor of vascular endothelial g
  316949                                                                                                A NOVEL APPROACH FOR TARGETING DNA TO DENDRITIC CELLS
                                                                                                                                  Australian National University
           Dr JOSEPH G ALTIN NHMRC Project Grants Standard Project Grant A NOVEL APPROACH FOR TARGETING DNA TO DENDRITIC CELLS IN VIVO FOR VACCINE
  334098   Prof Michael Abramson                                                                        What effects do tiny      Monash University
                                NHMRC Project Grants Standard Project Grant Cardiorespiratory effects of ultrafine particles particles have on the heart and lungs?
  359293   Prof Paul Mulvaney NHMRC Project Grants Development Grant                                    Q-Sand Mode Detection System For Melbourne
                                                                                                                                    Gallery Mode Technology
                                                                            Q-Sand (TM): Whispering Gallery (TM) WhisperingUniversity of Ultrasensitive and Label Free Testin
  379600                        NHMRC Project Grants Standard Project Grant Interaction of AngiotensinDrug therapy for aortic aneurysm formation
           Prof Jonathan Golledge                                                                                                 James Cook University
                                                                                                         II and PPARg in aortic aneurysm
  409918   A/Pr Sherry y y WU SCHOLARSHIP                                   Liposomal delivery of RNA inhibitorydelivery of RNA treatment nucleotides for treatment of cervical
                                                     Public Health Postgraduate Scholarship                                       University of Queensland
                                                                                                        Liposomal nucleotides for inhibitory of cervical cancer
  433613                                                                                                Killing colorectal cancer cells with targeted drug-loaded nanoparticles
                                                                                                                                  Ludwig Institute colorectal Research
           A/Pr Joan K Heath NHMRC Project Grants Standard Project Grant Development of drug-loaded antibody-targeted nanoparticles to killfor Cancer cancer cells
  433624   Dr Andrew HA Clayton NHMRC Project Grants Standard Project Grant Single Molecule Cell Biology                          Ludwig Institute for Cancer Research
                                                                                                        Signalling dynamics in living cells
  451903   Dr Natasha M RogersSCHOLARSHIP                                   Specific targeting of dendritic cellstargeting of dendritic Queen in allotransplantation
                                                     Medical Postgraduate Scholarship                                               liposomes Elizabeth Hospital
                                                                                                        Specific with tolerogenicThe cells with tolerogenic liposomes in allotrans
  455890                                                                                                Delivery of gene-silencing nucleotides
                                                                                                                                  University cervical cancers
           Dr Nigel AJ McMillan NHMRC Project Grants Standard Project Grant Non-viral vectors for targeted delivery of RNAi nucleotides to of Queensland
  455968                                                                                                 Mechanosensitive Channels as Nanodevices in Liposome Systems for T
                                                                                                                                  University of as Nanodevices
           Prof Boris Martinac NHMRC Project Grants Standard Project Grant Development of Bacterial Bacterial Mechanosensitive Channels Queensland
  456150                                                                                                MPM non-invasive imaging of biological interactions following drug delive
                                                                                                                                  University of Queensland
           Prof Mark AF Kendall NHMRC Project Grants Standard Project Grant MPM non-invasive imaging of biological interactions following drug delivery with micro-nanoproject
  456314   Miss Susan HUA       SCHOLARSHIP                                 Peripheral mechanisms of analgesiamechanisms of analgesia and the involvement of cell adhesio
                                                     Biomedical Postgraduate Scholarship                                          University of Queensland
                                                                                                        Peripheral and the involvement of cell adhesion
  471512   Dr Ross W Stephens NHMRC Project Grants Development Grant                                    Novel nanoparticles for molecular probes in diagnostic imaging
                                                                                                                                  Australian National University
                                                                            Novel nanoparticle composites for molecular probes in diagnostic imaging
  472665   Prof Karlheinz Peter NHMRC Project Grants Development Grant                                  MRI-nanoparticles for non-invasive diagnosis of Institute diseases
                                                                                                                                  Baker Heart Research vascular
                                                                            Novel single-chain antibody-targeted nanoparticles for diagnosis of vascular diseases in magnetic
  472668                        CAREER DEVELOPMENT AWARDS
           Dr Christoph E Hagemeyer                  Industry CDA                                       Nanoparticles fo diagnosis of vascular of vascular diseases
                                                                                                                                  Baker Heart Research
                                                                            Novel Single-chain antibody-targeted nanoparticles for diagnosisdiseases Institute
  479505   A/Pr Wei Duan                                                                                nanoliposome drug delivery systemdelivery system for the treatment of m
                                                                                                                                   lipid drug for the
                                NHMRC Project Grants Standard Project Grant A novel tumour-targeting A novel tumour-targetingDeakin University treatment of malignant glioma
  490908                        NHMRC Project Grants Standard Project Grant Inhibition of allergic airway inflammation by nanoparticles University inflammation by specific ty
           Prof Magdalena Plebanski                                                                                               of allergic
                                                                                                        Understanding inhibition Monash pulmonary
  491181                        NHMRC Project Grants Standard Project Grant Recognition of macromolecular complexes by cell Monash receptors: A novel mechanism of lipiddru
           A/Pr Christopher JH Porter                                                                                             surface University
                                                                                                        The importance of intestinal 'scavenger' receptors in the absorption of a
  511303                                                                                                Nano-Oncology             University of South Australia
           Prof Hans J Griesser NHMRC Project Grants Standard Project Grant IMMUNOTARGETED NANOPARTICLES TO IMPROVE TUMOUR DELIVERY OF CHEMOSENSIT
  525456   Dr Andrei V Rode                                                 Optical vortices for trapping and guiding nanoparticles incontaminationUniversity
                                NHMRC Project Grants Priming Grant (New Investigator)                                             Australian
                                                                                                        Air cleaning from nanoparticle air National
  568782                                                                                                Targeting cancer genes University of New South
                                                                                                                                   siRNA to therapy
           A/Pr Maria KavallarisNHMRC Project Grants Standard Project Grant Improving cancer therapy: nanoparticle delivery ofto improvecancer cells Wales
  569525                                                                                                Targeted delivery agents using inorganic nanoparticles
                                                                                                                                  University agents using antibodies and novel ino
           Prof Julie H CampbellNHMRC Project Grants Standard Project Grant Antibody-directed delivery of anti-restenotic of anti-restenotic of Queensland
  579705   Mr Justin L Bourke SCHOLARSHIP                                   Design and use              Design and use of conductive biopolymers in neural stem
                                                                                                                                  Monash University
                                                     Biomedical Postgraduate Scholarship of conductive biopolymers in neural stem cell network formation cell network fo
  546238   A/Pr James R Friend NHMRC Project Grants Development Grant                                   The NanoNautilus : A Breakthrough in of Successful Other Cerebrovas
                                                                                                                                  Monash University
                                                                            The NanoNautilus : A Breakthrough in the Successful Treatmentthe Strokes andTreatment of Strok
  569258   Dr Mark A Baker                                                  Identification and characterisation of phosphorylation events taking place during human sperm cap
                                NHMRC Project Grants Priming Grant (New Investigator)                                             University of Newcastle
                                                                                                        Identification of phosphorylation events taking place during human sperm
  569694                                                                                                Toxicology of Nanomaterials
           Prof Rod F Minchin NHMRC Project Grants Standard Project Grant The Toxicology of Nanomaterials                         University of Queensland
  569726                                                                                                against pandemic influenza: improved immune responses at a reduced d
                                                                                                                                   against influenza
           Prof Mark AF Kendall NHMRC Project Grants Standard Project Grant Nanopatch immunisation Nanopatch immunisationUniversity of Queensland
  572734   Prof Fiona M Wood NHMRC Project Grants Development Grant                                     Novel dresings to promote to promoteWesternhealing
                                                                                                                                  University of wound Australia
                                                                            Pre-clinical evaluation of nano-membrane dressings faster wound healing
  631720                                             Urgent Research - Pandemic Influenza
           Prof Mark AF Kendall NHMRC Strategic Awards                                                  H1N1 against pandemic University of Queensland virus A (H1N1) immu
                                                                                                                                   Novel against pandemic
                                                                            H1N1 Nanopatch immunisation Nanopatch immunisationA (H1N1) influenzaNovel 09: potent influen




Note: 254504 and 279408 is included because the CIA identified it as having some connection with Nanotechnology through an NHMRC Survey in 2005. On the basis that 279408 i
         App    Start
 State                  1997-98     1998-99    1999-00   2000-01   2001-02   2002-03   2003-04   2004-05   2005-06   2006-07   2007-08
         Year   Year
NSW      1997   1998      $26,640    $50,286   $48,533   $25,161
QLD      2000   2001                                               $210,794 $140,828    $70,414
WA       2002   2003                                                         $89,267   $156,000 $153,500   $76,750
WA       2002   2003                                                                   $106,250 $33,750
QLD      2003   2004                                                                    $49,875 $99,750    $99,750   $49,875
            QLD         2003      2004                                                                               $74,813 $24,938
            ACT         2004      2005                                                                               $73,375 $144,250 $141,750      $70,875
            VIC         2004      2005                                                                               $84,000 $155,500 $150,625      $79,125
            VIC         2004      2005                                                                                       $127,750
            QLD         2005      2006                                                                                        $69,688 $140,975     $144,012
            QLD         2005      2006                                                                                        $14,409 $27,315       $27,815
            VIC         2006      2007                                                                                                 $83,500     $169,078
            VIC         2006      2007                                                                                                 $46,750      $94,746
            SA          2006      2007                                                                                                              $48,549
            QLD         2006      2007                                                                                                   $68,025   $158,811
            QLD         2006      2007                                                                                                   $82,000   $165,643
            QLD         2006      2007                                                                                                   $70,175   $136,589
            QLD         2006      2007                                                                                                              $42,722
            ACT         2007      2008
            VIC         2007      2008                                                                                                              $10,703
            VIC         2007      2008
            VIC         2007      2008
            VIC         2007      2008                                                                                                              $88,170
            VIC         2007      2008                                                                                                              $64,993
            SA          2007      2008                                                                                                              $85,940
            ACT         2008      2009
            NSW         2008      2009
            QLD         2008      2009
            VIC         2008      2009
            VIC         2008      2009
            NSW         2008      2009
            QLD         2008      2009
            QLD         2008      2009
            WA          2008      2009
            QLD         2009      2009

                                                                                    $25,161 $210,794 $230,095 $382,539 $519,188 $713,035 $860,990 $1,387,771
                                                                                           1         1          2        4    6        8       10         15
ey in 2005. On the basis that 279408 is included, similar work by the same researcher (Golledge) has also been included.
                                                                        Broad Research        Field Of    Research Research
2008-09   2009-10   2010-11   2011-12   2012-13   2013-14   Total
                                                                               Area          Research        KW 1        KW 2
                                                             $150,620   Basic Science                    CHOLESTEROL  7-KETOCHOLESTEROL
                                                                                            Cardiology (incl. Cardiovascular Diseases)
                                                             $422,036   Basic Science                    Charged dendritic systems
                                                                                                                      Drug Delivery
                                                                                            Pharmaceutical Sciences and Pharmacy
                                                             $475,517   Basic Science                    calcium channels
                                                                                                                      hypoxia
                                                                                            Cardiology (incl. Cardiovascular Diseases)
                                                             $140,000                       Medical Virology          baculovirus protein expression system
                                                                        Clinical Medicine and Science antiviral compounds
                                                             $299,250                       Surgery
                                                                        Clinical Medicine and Science aortic aneurysm diabetes mellitus
                                                                     $99,751   Basic Science                     Charged dendritic systems
                                                                                                                               Drug Delivery
                                                                                                   Pharmaceutical Sciences and Pharmacy
                                                                   $430,250    Basic Science                     Cancer        DNA vaccine
                                                                                                   Tumour Immunology immunotherapy
                                                                   $469,250    Public Health                     Air pollution Health risk assessment
                                                                                                   Environmental and Occupational Health and Safety
                                                                   $127,750                        Aged Care Diagnostics Microspheres
                                                                               Clinical Medicine and Science Nursing
  $72,724                                                          $427,399                        Surgery                     drug
                                                                               Clinical Medicine and Science aortic aneurysm targeting
  $20,080     $7,172                                                 $96,791                       Pharmaceutical Sciences and Delivery of siRNA
                                                                               Clinical Medicine and Science Cervical Cancer Pharmacy
 $173,073    $87,495                                               $513,146    Basic Science                     anti-cancer drugs
                                                                                                                               antibody
                                                                                                   Therapies and Therapeutic Technology
  $97,055    $49,059                                               $287,610    Basic Science                     biochemistry
                                                                                                   Analytical Biochemistry biotechnology
  $32,316    $15,189                                                 $96,054   Basic Science                     Dendritic cells iposomes
                                                                                                   Transplantation Immunology  L
 $139,844    $49,059                                               $415,739    Basic Science                     Cancer        RNA
                                                                                                   Oncology and Carcinogenesis interference
 $169,171    $85,528                                               $502,342    Basic Science                                   Ion channels
                                                                                                   Biophysics Electron microscopy
 $131,631    $65,217                                               $403,612    Basic Science                     Epidermis Immunoregulation
                                                                                                   Cellular Immunology
  $12,909                                                            $55,631   Basic Science                     Antinociception
                                                                                                                               Cell
                                                                                                   Peripheral Nervous System adhesion
 $142,173    $28,544                                               $170,717    Basic Science                      and NuclearMolecular probes
                                                                                                                                Medicine
                                                                                                   RadiotherapyDiagnostic imaging
 $330,795   $119,300                                               $460,798                        Cardiology Activated monocytes platelets
                                                                                                                               Activated
                                                                               Clinical Medicine and Science (incl. Cardiovascular Diseases)
 $139,625    $94,250    $94,250   $47,125                          $375,250                        CLINICAL Cardiology Antherosclerosis
                                                                               Clinical Medicine and Science SCIENCES (incl. Cardiovascular Diseases)
 $189,668   $168,157    $84,078                                    $441,903    Basic Science       Surgery       drug deliverydrug targeting
 $178,248   $180,157    $90,078                                    $536,653                        Allergy
                                                                               Clinical Medicine and Science Allergic asthma   Dendritic cell
 $131,405   $132,825    $66,412                                    $395,635    Basic Science                     Drug absorption
                                                                                                                               dietary fat
                                                                                                   Pharmaceutical Sciences and Pharmacy
 $174,433   $179,538    $91,045                                    $530,956    Basic Science                     Biomaterials Cancer
                                                                                                   Biotechnology not elsewhere classified
 $105,538   $160,975   $155,575   $70,138                          $492,226    Basic Science                     Air TechniquesOccupational hazzards
                                                                                                   Instruments and purification from nanomaterials in nanotechnolog
  $94,750   $199,700   $204,800   $99,850                          $599,100    Basic Science                     drug sensitivity
                                                                                                   Oncology and Carcinogenesis nanoparticles
  $53,525   $107,050   $107,050   $53,525                          $321,150    Basic Science                     anti-restenosis therapy
                                                                                                                               cardiovascular disease
                                                                                                   Cardiology (incl. Cardiovascular Diseases)
  $12,464    $21,552    $17,008    $5,669                            $56,693                       Neurosciences not elsewhere classified Biopolymer Design
                                                                                                                               Electroactive
                                                                               Clinical Medicine and Science Autologous Neural Stem Cell Implantation
  $93,606    $93,606                                               $187,212                        Surgery                     endoscopic
                                                                               Clinical Medicine and Science cardiovascular disease surgery
  $45,875    $91,750    $91,750 $45,875                            $275,250    Basic Science                                   Phosphoproteomics
                                                                                                   ReproductionNano-flow LC-MS/MS
 $208,525   $449,204   $459,404 $427,250    $257,850   $49,325    $1,851,558   Basic Science                     Pharmacokinetics
                                                                                                                               Pharmacology - toxicology
                                                                                                   Toxicology (incl. Clinical Toxicology)
  $83,650   $167,300   $167,300 $83,650                            $501,900    Basic Science                     ImmunisationInfluenza
                                                                                                   Humoral Immunology and Immunochemistry
  $94,300    $94,300                                               $188,600                        Dermatology                 wound
                                                                               Clinical Medicine and Science nano-membranes dressings
  $44,868    $89,736    $44,868                                    $179,472                        Medical Virology
                                                                               Clinical Medicine and Science H1N1

$2,972,251 $2,736,663 $1,673,618 $833,082   $257,850   $49,325   $12,798,349
        26         24         13        8          1    1
  Research Research Research               Health     Health     Health Health Health Application         Unit
    KW 3          KW 4        KW 5          KW 1      KW 2       KW 3       KW 4     KW 5    Status      Status
CYCLODEXTRIN  MACROPHAGE   EFFLUX                                                                       Payments
                                                                                          Payments can be made can be made
              Oligonucleotide delivery Anti Angiogenesis Neovascularisation Gene Therapy
Lipophilic dendrimers                                                    Eye
                                                    Choroidal Drug Delivery Disease                     Payments
                                                                                          Payments can be made can be made
                                                    cardiac
mitochondriareactive oxygen species cardiac arrhythmia ischemiaion channel dysfunction                  Payments
                                                                                          Payments can be made can be made
              liposome     protein purification
flaviviurs encephalitis encapsulation                                                                   Payments
                                                                                          Payments can be made can be made
osteoprotegerin                                     aortic aneurysm
                                                               therapeutic target disease
                                          abdominal diabetes (type 2)    vascular                       Payments
                                                                                          Payments can be made can be made
                             Oligonucleotide delivery
Drug Design Lipophilic dendrimers                                                                                     Payments
                                                                                                        Payments can be made can be made
              L                            Cancer
Dendritic cells iposomes Targeting delivery of DNA                 Gene therapy
                                                       Cancer immunotherapy                 disease                   Payments
                                                                               Infectious Vaccine Payments can be made can be made
Panel studiesUltrafine particles                       Coronary artery disease function assessment
                                                                   Heart rate Lung
                                           Chronic obstructive pulmonary diseasevariability                           Payments
                                                                                                        Payments can be made can be made
NanotechnologyQuantum Dots   Whispering Gallery Modes                                                                 Payments
                                                                                                        Payments can be made can be made
pathogenesis                                           aortic aneurysm
                                                                    mechanisms vascular disease
                                           abdominal pathogenictreatment strategies                                   Payments
                                                                                                        Payments can be made can be made
Gene delivery Liposome RNA interference                                                                               Payments
                                                                                                        Payments can be made can be made
                             nanotechology
drug deliverymouse models of metastasis                colorectal cancer
                                           colon cancer metastasis             cancer prevention and treatment
                                                                                            immunotherapy of cancer Payments
                                                                                                         design
                                                                   colorectal drug delivery systemPayments can be made can be made
              quantum dots   single        biological sciences epithelial neoplasms/malignantPayments can be made can be made
                                                       cancer
epidermal growth factor receptor molecule spectroscopy biology                              ratio fluorescence spectroscopy
                                                                               growth factors/receptors               Payments
Tolerance Transplantation                                                                                             Payments
                                                                                                        Payments can be made can be made
              gene deliverynanoparticlesanti-tumour agents cancer
cervical cancer                                                                human                    Payments carcinoma
                                                                                                                      Payments
                                                       cervical genetic therapy papilloma virus/cervicalcan be made can be made
Lipid bilayersPatch clamping               Cancer chemotherapy systems
                             Protein structure                     Lipids
                                                       Drug delivery                                                  Payments
                                                                                                        Payments can be made can be made
               imaging       Topical       Delivery Immunoregulation Skin cell immunology
Non-invasiveSkin cell immunogy Drug Drug Delivery                  Non-invasive imaging                               Payments
                                                                                                        Payments can be made can be made
InflammationLiposomes Pain                                                                                            Payments
                                                                                                        Payments can be made can be made
              radiolabelling
Nanoparticle Nuclear medicine              Cancer                  Renal disease
                                                       Cardiovascular disease  Thrombosis                             Payments
                                                                                                        Payments can be made can be made
                             Targeted nanoparticles Cardiovascular disease
Dendrimer Single-chain antibodies Atherosclerosis                                           Pulmonaryimaging
                                                                                                         embolism     Payments
                                                                   Diagnosis Magnetic resonancePayments can be made can be made
              Cardiovascular risk
                             Endothelial Magnetic during antherosclerosis
Cardiovascular disease prevention dysfunctionresonance imaging                                          Accepted      Payments can be made
neurosurgerypharmaceutics                              drug        glioblastoma
                                           brain tumour delivery systems                    pharmacotherapy can be made can be made
                                                                               pharmaceutical treatment Payments      Payments
              Nanoparticle T cell
Lung homeostasis                                       Allergen Asthma and allergic disease prevention can Payments
                                                                               Immunomodulation Payments
                                                                                            Prevention and tract      of asthma
                                           Airway inflammationinduced inflammation in the respiratorytreatmentbe made can be made
drug transport               pharmaceutics
              epithelial transport         Diabetes Drug delivery                                       Payments can be made
                                                                   Nutrition Obesity pharmaceutical treatment Payments can be made
              M              Radiolabeling
Drug targeting onoclonal antibody                      Cell death Mouse models of cancer
                                           Antibody cancer therapy                          Tumour Accepted
                                                                               Novel therapeutic specific targeting Payments can be made
              Trapping nanoparticles for toxicology assessments Impact of NanotechnologyPayments and Safety in can be made
                                                        Environmental
                                                                   Nanomaterials and health to factor
                                                                               Nanoparticles risk Nanomaterials Payments
                                                                                            Occupational
Optical trapping of nanoparticles in air Health andHuman and Environmental Exposure safety Health can be made Nanotechnology Industry
    siRNA solid tumours    targeted therapy cancer              gene silencing cancer
                                                  chemosensitization          lung                      Accepted      Payments can be made
drug deliverydrug targeting  nanotechnology            drug        restenosisrestenosistargeted therapy
                                           atherosclerosis delivery systems                             Accepted
                                                                                             after angioplasty        Payments can be made
              Nanobiotechnology Analysis Network
                             Neural
Fluorescence Imaging and ImageStem CellMethods Formation and Testing                                    Accepted      Payments can be made
                technology
endovascularneurosurgerystroke                         cerebrovascular accident/stroke
                                           cerebral embolism neurosurgery                   traumatic brain
                                                                                                        Accepted      Accepted
                                                                               stroke/cerebral ischaemiainjury/neurotrauma
              Tyrosine       pp60c-SRC
Sperm Capacitation phosphorylation Hyperactivation                 Immature Male infertilitySperm       Accepted
                                                       Idiopathic infertility sperm maturationmotility defects        Payments can be made
Toxicology                                             pharmacology - toxicology
                                           pharmacokinetics        toxicity                             Accepted      Payments can be made
              Topical drug delivery Development Drug delivery
Skin Immunology              Vaccine                               Immune Responses Influenza Accepted
                                           Alternative Vaccination Strategies  Improvement of Vaccine Efficacy Payments can be made
wound healing                                           injuries skin repair
                                           Cutaneouschronic and acute injuries                          Accepted      Payments can be made
                                                                                                        Approved      No Unit Found

				
DOCUMENT INFO
Description: Application of Nanotechnology to Biomedical Studies document sample