Treatment of coronary artery disease _81734

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					?Treatment of coronary artery


Treatment of coronary artery disease

The first section provides an overview of the

Coronal A heart disease, coronary heart disease or coronary artery disease A (CHD),
sometimes known as the coronal A disease (CAD) ischaemic heart diseases. Means
that due to coronary artery narrowing or blockage causing myocardial ischemia,
Anoxia due to heart disease. Henan province people's hospital medicine unit

Epidemiology of the disease in over 40 years, men more than women, mostly in
mental work, before and after the first world war is not over, after the second world
war, the disease gradually increased, to become the main cause of death in the
population, reach peak after the 1960s. Disease in China as in Europe and the United
States, there is a growing trend in recent years, 1976 in 12 cities in statistics, the
disease mortality 29.6/10 million higher than in the North to the South, the 70 's 22
provinces, autonomous regions and municipalities prevalence among people over 40
years of age, and 6.46% year on year increase.

Etiology and pathogenesis of the disease is caused by A atherosclerosis. A on
coronary atherosclerosis, the most important risk factors are old, male,
Hyperlipidemia, high blood pressure, smoking and diabetes. This was followed by
brain activity to reduce tension and physical activity, food, animal fat, cholesterol and
antioxidants such as vitamin E, A small, obesity, A personality, and so on. As for
coronary atherosclerosis is likely to occur, it may be: the infective and A portion of
the film's blood supply by lumen direct supply, blood oxygen and nutrients directly
into the endometrium and lipid membrane, thus also easy penetration; ‫ڠ‬the A and the
primary A angle almost at right angles to its proximal proximal and branch, by blood
flow and endometrial-impact vulnerable.

In the pathogenesis of comparison, in recent years, emphasizing the increasing
macrophages and wander back and forth, the proliferation of smooth muscle and C
above. Eating and the accumulation of lipids in the role of fibroblasts proliferation
and the formation of fiber fat disease; platelet adhesion and aggregation, endothelial
damage and hyperplasia C, thrombosis, and these C hyperplasia and linger. While all
of these cells are released from a variety of factors, these factors through various
channels to promote the formation of A atherosclerosis, and also promote the
proliferation and movement of the disease.

Pathological anatomy and pathophysiology: Coronal A left, right, 2 branches, opening
in the left and right master A sinus. Left coronary A 1-3cm long total dry, and then
divided into anterior descending and swing. A three-Coronal many small branch
consistent with left main coronary, collectively A coronal A4. Atherosclerosis may
involve four in one, two or three or four at the same time. With most of the left
anterior descending coronary artery disease, also the heaviest, and then turn to the
right coronary roundabout branch A, left, and left A backbone of coronavirus. Lesions
are more in the proximal and distal, main branch with edge. Plaque in the arteries
branch openings, often biased towards one side of the vessel, the Crescent-shaped, it
can gradually cause the development of lumen stenosis or occlusion.

Coronary atherosclerosis develops to a certain extent, affect myocardial blood supply,
when the vessel was slightly narrow (less than 50%), myocardial blood supply is not
affected, asymptomatic patients, a variety of stress but also do not show performance
of myocardial ischemia, notwithstanding the atherosclerosis, also could not be
considered have coronary heart disease, Vascular Stenosis full degree (> 50% to 75%),
with a total capacity of myocardial ischemia, myocardial reduction occurred ischemia
is coronary heart disease.

In addition, the atherosclerotic plaque rupture or bleeding, atherosclerosis of the
coronary artery spasm or thrombosis in A may make A cavity quickly serious stenosis
or blocked, causing myocardial ischemic or necrosis.

Clinical types of parts due to the scope and extent of the disease have different
clinical characteristics, are generally divided into five types:

1. the occult or asymptomatic coronary artery disease: asymptomatic, but some
myocardial ischemia ECG changes or radionuclide myocardial Imaging changes,
changes of myocardial free.

2. angina: paroxysmal pain substernal, for a moment of myocardial ischemia,
myocardial without changes.

3. acute myocardial infarction: symptoms of serious, as A block of coronavirus,
myocardial ischemic necrosis.

4. ischemic heart disease: chronic myocardial ischemia-induced cardiac fibrosis past
heart gradually fibrosis or cardiac sclerosis, performance for the heart, heart failure
and arrhythmias.

5. sudden death: sudden cardiac arrest and death for cardiac electrophysiological
disorders occur locally or pacing conduction disturbance caused by serious occurrence
of cardiac arrhythmias. (To be continued)
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