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Shaping Arizona’s Future Bioscience Economy
Phoenix, Arizona
Saundra E. Johnson
Executive Vice President
Arizona HIMSS
May 8, 2009
Flinn Foundation
Private foundation
(Phoenix physician and
spouse bequests)
$215M endowment
(12/07)
9 member Board (50%
M.D. or Ph.D.)
$10M+ annual
distribution (Arizona
specific)
Arizona’s Bioscience Roadmap
Developed by Battelle in 2002
Extensive research, interviews, focus
groups, economic analysis
10-year statewide plan
Guided by committees of statewide
leaders in science, business, policy
Arizona’s Bioscience Roadmap
Develop Arizona as a global biomedical
research and bioscience commercial
center over the next 20 years.
OBJECTIVES
Leapfrog research opportunities
Catalyze bioscience commercialization
ACTIONS
Make strategic investments in research
infrastructure
Make strategic investments in
commercialization
Recruit intellectual capital
Provide guidance, support and
information on the biosciences
Defining the Biosciences
Agricultural Drugs & Medical Devices Hospitals Research, Testing &
Feedstock & Chemicals Pharmaceuticals & Equipment Medical Laboratories
Agricultural Medicinal & Laboratory Specialty Biological
processing botanicals apparatus & hospitals research
Basic organic furniture
Pharma- University Commercial
chemicals ceutical Surgical, medical medical
Ethyl alcohol preparations medical, dental, research research
mfg. ophthalmic hospitals
Diagnostic & analytical Testing
Organic fiber substances instruments & Clinical laboratories
mfg. equipment research
Biological institutions
Medical
Fertilizers products Irradiation laboratories
apparatus & & diagnostic
Pesticides and imaging
other agricultural electromedical
centers
chemicals equipment
Product-Oriented Service-Oriented
Battelle Research Convergence
Core Competencies Three Big O’s
Bio-engineering Genomics
Cancer therapetutics Proteomics
Neurosciences Bio-Informatics
Bio-imaging
Existing Strengths
Electronics
Optics
Advanced
manufacturing
Why Arizona Invests in Bio
Size and range of economic activity means economic
diversity; significant new firms; and high paying,
secure jobs across spectrum of employment areas
veterinary environmental biological
testing testing
Services remediation
Research
agriculture pharmaceuticals
organic surgical
chemicals appliances
devices
medical
labs
Manufacturing
Why Arizona Invests in Bio
It’s a focal point for technology convergence
and continuing technology development
Electronics
Imaging
Information
Biosciences processing
Materials Artificial
intelligence
Our Statewide Approach
Flagstaff
Sun City/
Surprise Scottsdale
Phoenix Chandler
Tempe
Oro Valley Tucson
Bio Champions
Bioscience Roadmap Steering Committee
80+ members
statewide
senior leadership
public: university vice presidents of research,
research institute CEOs, legislators, mayors and
city council members, governor's staff, school
superintendents
private: regional business leaders, bio company
senior executives, hospital administrators,
foundation CEOs
Arizona’s Bioscience Roadmap
Arizona’s Bioscience Roadmap Steering Committee
Martin Shultz, Pinnacle West Capital Corp., Chair
Rt. Brig. Gen. Ron Shoopman, Southern Arizona Leadership Council, Vice Chair
Communications & Public Affairs Workforce Education Investment & Capital Formation Research
Paul Allvin, UA TBD, Banner Health Catherine McKee, Morrison Institute Lawrence Aldrich, C-Path Joseph Rogers, Ph.D., SHRI
MaryAnn Guerra, Catapult Bio Steve Kiefer, MCCCD Jim Zaharis, Ed.D., GPL Quinn Williams, Esq., Greenberg Traurig Stuart Williams, Ph.D., BIO5
Co-Chairs Co-Chairs (2008) Co-Chairs Co-Chairs (2007) Co-Chairs (2007)
Asthma Bio-Ag
Federal & State Relations Fernando Martinez, M.D, BIO5 Charles Arntzen, Ph.D.,
Jack Lunsford, Westmarc AERO Capital Richard Robbins, M.D. Biodesign
Formation Carl T. Hayden VA Med. Ctr Vicki Chandler, Ph.D., BIO5
Jaime Molera, ABOR/UA
Committee Co-Chairs (2007) Co-Chairs (2007)
Co-Chairs
Bioimaging
.
Northern Arizona Roadmap Central Arizona Southern Arizona Bioengineering
John Haeger, NAU Roadmap Ranu Jung, Ph.D., Biodesign Robert Gillies, Ph.D., BIO5
Collaborations with cities,
Hon. Sara Presler, City of Stuart Williams, Ph.D., BIO5 Jim Pipe, Ph.D., BNI
universities, government, Hany Massarany, Ventana
Flagstaff Medical Systems Co-Chairs (2006) Co-Chairs (2006)
business, economic
Co-Chairs development organizations Leslie Tolbert, UA
Co-Chairs
Cancer Research Neurological Sciences
Eugene Gerner, Ph.D., BIO5 Frank Porreca, Ph.D., UA
Larry Miller, Ph.D. Mayo Clinic Joseph Rogers, Ph.D., SHRI
Co-Chairs (2006) Co-Chairs (2006)
Legend:
= Active Grand Challenges
Collaboration
Laura Huenneke, Ph.D., NAU
= On-Call Rick Shangraw, P.h.D., ASU
AZTransNet
Leslie Tolbert, Ph.D., UA
= Spinoff
Metrics of Success
2002-2007
Metrics Performance Comments
NIH Funding 24% (’02-’07) Arizona performance outpacing top 10 States ( 11%) and U.S.
( 11%)
Bio Jobs 23% (’02-’07) Arizona’s growth far exceeding country
Bio Firms 22% (’02-’07) Medical devices; research, testing and medical labs are key
segments
Bio Wages 34% (’02-’07) Average salary: $52.5K
2002-2008
Metrics Performance Comments
Bio Risk Capital 41% (’02-’08) Reached 86% of goal in 2007 but only 65% of goal in 2008
Bio University IP
Bio Startups 50% (’02-’08) 42 bio startups 2002-08
Bio Licenses 15% (’02-’08) 176 licenses 2002-08
Bio Income 18% (’02-’08) Total of $14.4 m. 2002-08; significant decline in 2008 over
2006-07 levels
Arizona Bioscience Impact, Growth
Annual total economic activity generated by the biosciences increased 46.6%
from $14.5 billion to $21.2 billion
Jobs from the total impact of the biosciences rose by almost 15,000 from 140,654
to 155,631
Annual state and local taxes generated grew 35% to $765.7 million
Total and % Change in Direct and Total Impacts of the Entire Bioscience Sector, 2002 - 2007 ($ in millions)
Direct Direct % Change Total Total % Change
Item Impact Impact 2002 - Impact impact 2002 - 2007
2002 2007 2007 2002 2007
Output $7,975.7 $12,539.3 57.2% $14,451.2 $21,185.0 46.6%
Employment 72,855 87,417 20.0% 140,654 155,631 10.6%
Employee
$3,203.6 $5,327.5 66.3% $5,176.6 $7,830.2 51.3%
Compensation
State and Local Tax
– – $566.9 $765.7 35.1%
Revenues
Source: Battelle TPP and IMPLAN
Arizona Non-Hospital Bioscience Impact, Growth
Annual total economic activity generated by the non-hospital biosciences sector
increased 61.6% from $3.6 billion to $5.8 billion
Jobs from the total impact of the non-hospital biosciences rose by 17.6% - 4,440
jobs from 25,231 to 29,671
Annual state and local taxes generated grew 34% to $177.8 million
Total and % Change in Direct and Total Impacts of the Non-Hospital Bioscience Sector, 2002 – 2007
($ in millions)
Direct Direct % Change Total Total % Change
Item Impact Impact 2002 - Impact impact 2002 - 2007
2002 2007 2007 2002 2007
Output $2,147.3 $3,641.2 69.6% $3,615.3 $5,842.8 61.6%
Employment 10,895 13,543 24.3% 25,231 29,671 17.6%
Employee
$494.1 $777.8 57.4% $949.5 $1,445.9 52.3%
Compensation
State and Local Tax
– – $132.5 $177.8 34.2%
Revenues
Source: Battelle TPP and IMPLAN
Arizona Bioscience Wages
Avg. Annual Avg. Annual Increase,
Major Industries & Bioscience Subsectors
Wages, 2006 Wages, 2007 06-07
Management of Companies and Enterprises $ 66,311 $ 74,293 12.0%
Drugs & Pharmaceuticals $ 56,274 $ 62,540 11.1%
Professional, Scientific, and Technical Services $ 57,527 $ 62,192 8.1%
Research, Testing, & Medical Laboratories $ 57,031 $ 60,564 6.2%
Finance and Insurance $ 58,895 $ 59,487 1.0%
Manufacturing $ 57,627 $ 58,402 1.3%
Total Non-Hospital Biosciences $ 53,369 $ 56,634 6.1%
Information $ 51,151 $ 53,337 4.3%
Total Biosciences $ 48,674 $ 52,481 7.8%
Hospitals $ 47,763 $ 51,685 8.2%
Medical Devices & Equipment $ 48,958 $ 51,651 5.5%
Health Care and Social Assistance $ 42,962 $ 44,912 4.5%
Transportation and Warehousing $ 42,151 $ 44,154 4.8%
Construction $ 40,907 $ 42,526 4.0%
Real Estate and Rental and Leasing $ 43,008 $ 42,306 -1.6%
Total Private Sector $ 39,526 $ 41,044 3.8%
Agricultural Feedstock & Chemicals $ 39,875 $ 40,449 1.4%
Retail Trade $ 28,393 $ 28,492 0.3%
Source: Battelle analysis of BLS, QCEW data from the Minnesota IMPLAN Group. Wages are in current dollars (not adjusted for inflation).
Projected Bioscience Job Growth
Among overall primary bioscience occupations (both clinical and non-clinical),
latest projections for 2006-16 show a 10-year expected growth rate for bio-related
jobs at twice that for all occupations (32% vs. 15%, respectively)
Projected Annual Openings in Arizona Bioscience Occupations, 2006-16
Healthcare Support 2,842
Health Technologists &
Technicians
2,253
Registered Nurses 1,741
Allied Health Therapists 343
Growth Openings
Pharmacists 264 Replacement Openings
Medical & Clinical Lab
236
Technicians
Physician Assistants 83
- 500 1,000 1,500 2,000 2,500 3,000
Source: Battelle analysis of Occupational Employment Projections data from the Arizona LMI Office.
HEALTH CARE AND THE LIFE SCIENCES
Key Trends in Health Care and the Life Sciences
Two new disciplines have emerged to be recognized
as powerful new approaches to research and health
care:
Systems biology, which seeks to integrate different levels
of information about the parts of a biological system to
understand how that system functions as a whole.
Translational Science, which encompasses both the
acquisition of new knowledge about health and disease
prevention, preemption, and treatment and the
methodical research necessary to develop or improve
research tools.
New health informatics / bioinformatics and data
management approaches are emerging to deal with
the acquisition, storage, retrieval and use of medical
and research information.
Source: : PricewaterhouseCoopers
Personalized Medicine
Personalized Medicine is medicine that examines each individual's
biological makeup and designs tailored strategies for maintaining
and enhancing health and wellness and treating illness.
Most traditional healthcare companies (payers,
providers, pharma, biotech) are moving aggressively
into this market through R&D, JVs, acquisitions, and
new product development
However, many of the winners in the market are likely to
come from non-healthcare companies like Google,
Microsoft, Cisco, Intel, P&G, Wal-Mart, and startups better
able to operate in the new paradigm
Source: : PricewaterhouseCoopers
Personalized Medicine
We are at a tipping point in Personalized Medicine, driven rapid
technological advances as well as other changes.
Advances in personalized medicine are driven by many forces that include
Collapsing technology costs in genomics and proteomics; within five years,
genomes will be sequenced for $100 in an hour at any doctor’s office
Increased process speed, storage, and bandwidth capacity enables IT
therapeutic design; we can now apply IT tools to design drugs on a virtual
basis
Ubiquitous connectivity allows customized solutions in disease management
and health and wellness; developments such as telehealth, homehealth, and
web applications enable a new paradigm in personalized care outside the
clinic
Pay-for-performance, evidence / outcomes-based, consumer-directed
healthcare will alter the standard of care from generic to specific; one size
does not fit all
Consumer empowerment, information and risk management creates
educated and demanding consumers; the scope of solutions across the health
and wellness continuum based is increasing base on consumer choice and
perceived value
Source: : PricewaterhouseCoopers
Personalized Medicine: New Partnership
Stellar leadership team:
Hartwell, Trent, Poste
Led locally by TGen/ASU;
also involves Arizona
research universities,
institutes, healthcare Lee Hartwell, Ph.D.
providers, industry partners
$45 million start-up
package
Proteomics next frontier in
post-genomic era
Arizona as international hub
of proteomic research and Jeffrey Trent, Ph.D. George Poste, DVM, Ph.D.
discovery
Biozona
Quality of life: Local access to the newest medical
discoveries and top healthcare practitioners. Local
research helps local patients first.
Economic rewards: High-paying, secure jobs that
create a stronger, more diversified statewide
economy. More jobs, better-quality jobs.
The Right ingredients: Statewide collaboration, top
talent, excellence in targeted research areas, long-
term strategy, and rapid progress. Collaboration
accelerates research.
Summary
Commitment of public/private sector
leadership has been sustained
Strong private/public partnerships have
mobilized to support the Roadmap
The bioscience sector is a growing driver of
our economy with clusters of bioscience firms
focused on specialized niches
Summary (Con’t)
A challenge for Arizona’s policymakers will be
to continue to invest in light of decreased
federal funding and fiscal pressures
But investing in the biosciences will result in
significant benefits
Good well-paying jobs that will create economic
opportunities and an improved quality of life
Better healthcare for citizens
Alternative fuels that can decrease U.S.
dependence on oil and improve environment
quality
More Information
www.flinn.org
Contact
Saundra E. Johnson
Executive Vice President
Flinn Foundation
1802 N. Central Avenue
Phoenix, AZ 85002
Voice: (602) 744-6831
E-mail: sjohnson@flinn.org
Web: www.flinn.org
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