Course Title Biotechnology Subject Life Science Course Length Semester

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					Course Title: Biotechnology                                       ECASD Curriculum Template                                        Date: November 2004
Subject: Life Science                                                    2004-05                                                   Grade Level: 10-12
Course Length: Semester

UNIT TITLE: (1) History and Development Biotechnology                                               TIMELINE (LENGTH OF UNIT): 2 weeks
                                                                                                                                                 Essential District
                                                                                                      Assessment              Essential
         Performance Standards                                 Learning Targets                                                                    Instructional
                                                                                                       Type(s)                Questions
                                                                                                                                                     Materials
B.12.1 Show* how cultures and individual   s    Identify and explain the beginnings and             SR and CR            What is
       have contributed to the development      development of biotechnology.                                            biotechnology?
       of major ideas in the earth and space,
       life and environmental, and physical     Demonstrate current practice (fermentation, cell    PA and O             How and why have
       sciences                                 culture, food production) through lab activities.                        cultures and
                                                                                                                         individuals
B.12.2 Identify* the cultural conditions that   Relate and compare these lab practices to the                            developed
       are usually present during great         beginnings and development of biotechnology         CR                   biotechnology from
       periods of discovery, scientific         techniques.                                                              its beginnings to its
       development, and invention                                                                                        current and future
                                                                                                                         applications?
B.12.3 Relate* the major themes* of science
       to human progress in understanding                                                                                How have
       science and the world                                                                                             biotechnology
                                                                                                                         techniques changed
B.12.4 Show* how basic research and             *All three learning targets are associated with                          through history?
       applied research contribute to new       each standard.
       discoveries, inventions, and
       applications

B.12.5 Explain* how science is based on
       assumptions about the natural world
       and themes* that describe the natural
       world




      Assessment Types:     SR = Selected Response (matching, multiple choice, T/F)       PA = Performance Assessment (performance or authentic tasks)           1
                            CR = Constructed Response (short answer/essay)                O = Observation (interactive and non-interactive)
Course Title: Biotechnology                                       ECASD Curriculum Template                                        Date: November 2004
Subject: Life Science                                                    2004-05                                                   Grade Level: 10-12
Course Length: Semester

UNIT TITLE: (2) Genetics and DNA Science                                                           TIMELINE (LENGTH OF UNIT): 2 weeks
                                                                                                                                                 Essential District
                                                                                                      Assessment              Essential
        Performance Standa rds                                 Learning Targets                                                                    Instructional
                                                                                                       Type(s)                Questions
                                                                                                                                                     Materials
F.12.3 Explain* current scientific ideas and    Identify and describe the important molecules      SR and CR             How do the
       information about the molecular and      and enzymes related to DNA structure, DNA                                physical and
       genetic basis of heredity                replication, transcription, and translation.                             chemical attributes
                                                                                                                         of DNA lead to all
                                                Explain and simulate the processes of DNA                                life processes?
                                                replication, transcription, and translation.    CR, PA and O
F.12.4 State the relationships between          Explain and simulate how the physical structure CR, PA and O             How can we modify
       functions* of the cell and functions     of DNA leads to the production of proteins.                              and manipulate
       of the organism as related to genetics                                                                            DNA in order to
       and heredity                             Explain how the physical structure of proteins                           modify and
                                                leads to phenotypic expression.                    CR                    manipulate life
                                                                                                                         processes for our
                                                Explain how manipulation (natural or artificial)                         benefit?
                                                of DNA leads to changes in phenotypic              CR
                                                expression.




      Assessment Types:     SR = Selected Response (matching, multiple choice, T/F)       PA = Performance Assessment (performance or authentic tasks)           2
                            CR = Constructed Response (short answer/essay)                O = Observation (interactive and non-interactive)
Course Title: Biotechnology                                        ECASD Curriculum Template                                         Date: November 2004
Subject: Life Science                                                     2004-05                                                    Grade Level: 10-12
Course Length: Semester

UNIT TITLE: (3) DNA Analysis Techniques                                                             TIMELINE (LENGTH OF UNIT): 6 weeks
                                                                                                                                                   Essential District
                                                                                                        Assessment              Essential
         Performance Standards                                  Learning Targets                                                                     Instructional
                                                                                                         Type(s)                Questions
                                                                                                                                                       Materials
This unit is an extension of the life science    Explain where restriction enzymes come from         CR                    What techniques are
standards and includes an extension of the       and how they work.                                                        used to analyze
science inquiry and science applications                                                                                   DNA?
standards as well.                               Explain and demonstrate the processes of            CR, PA and O
                                                 restriction digestion, and restriction mapping.                           What are the
                                                 Explain how gel electrophoresis exploits the        CR                    applications of
                                                 physical characteristics of DNA to separate                               these techniques
                                                 fragments of DNA.                                                         with regard to
                                                                                                                           manipulating and
                                                 Explain and demonstrate how gel                     PA and O              modifying DNA?
                                                 electrophoresis is used to separate and analyze
                                                 DNA fragments for multiple purposes. (i.e.
                                                 restriction mapping, forensics, quality control,
                                                 etc.)
                                                 Explain how the process of polymerase chain         CR
                                                 reaction (PCR) exploits the physical
                                                 characteristics of DNA to generate multiple
                                                 copies of DNA.

                                                 Simulate or demonstrate the process of DNA          PA and O
                                                 amplification through PCR.
                                                 Explain the process of DNA sequencing and           CR
                                                 how it relates to the science of genomics.

                                                 Simulate or demonstrate the process of DNA
                                                 sequencing.                                         CR, PA and O




      Assessment Types:      SR = Selected Response (matching, multiple choice, T/F)        PA = Performance Assessment (performance or authentic tasks)           3
                             CR = Constructed Response (short answer/essay)                 O = Observation (interactive and non-interactive)
Course Title: Biotechnology                                    ECASD Curriculum Template                                         Date: November 2004
Subject: Life Science                                                 2004-05                                                    Grade Level: 10-12
Course Length: Semester

UNIT TITLE: (3) DNA Analysis Techniques                                                          TIMELINE (LENGTH OF UNIT): 6 weeks
                                                                                                                                               Essential District
                                                                                                    Assessment              Essential
       Performance Standards                                Learning Targets                                                                     Instructional
                                                                                                     Type(s)                Questions
                                                                                                                                                   Materials
                                             Explain the process of hybridization and            CR
                                             blotting techniques.

                                             Simulate or demonstrate the processes of            CR, PA and O
                                             hybridization and blotting techniques.

                                             Formulate and prepare a lab write up based on       PA
                                             one or more activities in this unit.


                                             *Optional*

                                             Explain the uses of nanotechnology in               CR
                                             biotechnology. (ie. DNA chips, etc)

                                             Explain and demonstrate how BLAST                   CR and PA
                                             searching can facilitate more efficient practical
                                             applications of biotechnology.

                                             Explain how bioinformatics can be used to           CR
                                             collect, store, and manage data from various
                                             biotechnology techniques.




     Assessment Types:   SR = Selected Response (matching, multiple choice, T/F)        PA = Performance Assessment (performance or authentic tasks)           4
                         CR = Constructed Response (short answer/essay)                 O = Observation (interactive and non-interactive)
Course Title: Biotechnology                                        ECASD Curriculum Template                                        Date: November 2004
Subject: Life Science                                                     2004-05                                                   Grade Level: 10-12
Course Length: Semester

UNIT TITLE: (4) Genetic Engineering – Processes and Applications                                     TIMELINE (LENGTH OF UNIT): 3 weeks
                                                                                                                                                  Essential District
                                                                                                       Assessment              Essential
         Performance Standards                                  Learning Targets                                                                    Instructional
                                                                                                        Type(s)                Questions
                                                                                                                                                      Materials
This unit is an extension of the life science    Explain and the general process of genetic          CR                   How can organisms
standards and includes an extension of the       engineering (recombinant DNA technology).                                be modified in order
science inquiry and science applications                                                                                  to produce a
standards as well.                               Demonstrate how genetic information can be                               product to improve
                                                 transferred from one organism to another in         PA and O             humanity?
                                                 order to produce a product.

                                                 Demonstrate how products can be collected and
                                                 purified.                                           PA and O
G.12.4 Show* how a major scientific or           Incorporate the processes of genetic                CR and O
       technological change has had an           engineering into a discussion of multiple
       impact on work, leisure, or the home      agricultural applications of genetic engineering.
                                                 (ie. Bt corn, papayas, tomatoes, BGH, golden
                                                 rice, etc.)                                         CR and O

                                                 Incorporate the processes of genetic
                                                 engineering into a discussion of multiple
                                                 medical applications of genetic engineering. (ie.
                                                 insulin, gene therapy, vaccine development,
                                                 edible vaccines, etc.)
G.12.5 Choose a specific problem in our          Research a specific topic in genetic engineering PA and O
       society, identify* alternative            and compose a presentation (text, web based,
       scientific or technological solutions     PowerPoint, others) for the entire class.
       to that problem and argue its merits




      Assessment Types:      SR = Selected Response (matching, multiple choice, T/F)       PA = Performance Assessment (performance or authentic tasks)           5
                             CR = Constructed Response (short answer/essay)                O = Observation (interactive and non-interactive)
Course Title: Biotechnology                                        ECASD Curriculum Template                                         Date: November 2004
Subject: Life Science                                                     2004-05                                                    Grade Level: 10-12
Course Length: Semester

UNIT TITLE: (5) Cloning and Stem Cells                                                              TIMELINE (LENGTH OF UNIT): 2 weeks
                                                                                                                                                   Essential District
                                                                                                        Assessment              Essential
         Performance Standards                                  Learning Targets                                                                     Instructional
                                                                                                         Type(s)                Questions
                                                                                                                                                       Materials
This unit is an extension of the life science    Explain the processes of therapeutic and            CR                    How will cloning
standards and includes an extension of the       reproductive cloning.                                                     and stem cell
science inquiry and science applications                                                                                   applications change
standards as well.                               Hypothesize and discuss the potential          CR and O                   the way diseases
                                                 applications of therapeutic and reproductive                              and death are dealt
                                                 cloning.                                                                  with?
                                                 Explain how embryonic and adult stem cells are CR
                                                 harvested and cultured.                                                   How will cloning
                                                                                                                           and stem cells affect
                                                 Hypothesize and discuss the potential               CR and O              quality of life?
                                                 applications of embryonic and adult stem cell
                                                 research.




      Assessment Types:      SR = Selected Response (matching, multiple choice, T/F)        PA = Performance Assessment (performance or authentic tasks)           6
                             CR = Constructed Response (short answer/essay)                 O = Observation (interactive and non-interactive)
Course Title: Biotechnology                                      ECASD Curriculum Template                                         Date: November 2004
Subject: Life Science                                                   2004-05                                                    Grade Level: 10-12
Course Length: Semester

UNIT TITLE: (6) Ethical, Legal, and Social Implications of Biotechnology                          TIMELINE (LENGTH OF UNIT): 3 weeks
                                                                                                                                                 Essential District
                                                                                                      Assessment              Essential
        Performance Standards                                 Learning Targets                                                                     Instructional
                                                                                                       Type(s)                Questions
                                                                                                                                                     Materials
H.12.1 Using the science themes* and           Express educated opinions on how the human          CR and O              How will political,
       knowledge of the earth and space,       genome project has and will continue to impact                            judicial, and
       life and environmental, and physical    human society.                                                            theological
       sciences, analyze* the costs, risks,                                                                              decisions related to
       benefits, and consequences of a         Express educated opinions on how embryonic          CR and O              these topics affect
       proposal concerning resource            and adult stem cell research and therapies have                           society?
       management in the community and         and will continue to impact human society.
       determine the potential impact of the                                                                             How can I apply the
       proposal on life in the community       Express educated opinions on how therapeutic                              material in this
       and the region                          and reproductive cloning have and will              CR and O              course to the
                                               continue to impact human society.                                         decisions I make
H.12.3 Show* how policy decisions in                                                                                     throughout my life?
       science depend on many factors,
       including social values, ethics,
       beliefs, time-frames, and
       considerations of science and           * All of these learning targets are associated
       technology                              with each standard.

H.12.5 Investigate* how current plans or
       proposals concerning resource
       management, scientific knowledge,
       or technological development will
       have an impact on the environment,
       ecology, and quality of life in a
       community or region




     Assessment Types:     SR = Selected Response (matching, multiple choice, T/F)        PA = Performance Assessment (performance or authentic tasks)           7
                           CR = Constructed Response (short answer/essay)                 O = Observation (interactive and non-interactive)
Course Title: Biotechnology                                      ECASD Curriculum Template                                         Date: November 2004
Subject: Life Science                                                   2004-05                                                    Grade Level: 10-12
Course Length: Semester

UNIT TITLE: (6) Ethical, Legal, and Social Implications of Biotechnology                          TIMELINE (LENGTH OF UNIT): 3 weeks
                                                                                                                                                 Essential District
                                                                                                      Assessment              Essential
        Performance Standards                                 Learning Targets                                                                     Instructional
                                                                                                       Type(s)                Questions
                                                                                                                                                     Materials
H.12.1 Using the science themes* and           Express educated opinions on how genetically        CR and O
       knowledge of the earth and space,       modified crops and livestock have and will
       life and environmental, and physic al   continue to impact human society.
       sciences, analyze* the costs, risks,
       benefits, and consequences of a         Express educated opinions on the legal
       proposal concerning resource            implications of patenting genes, availability of
       management in the community and         genetic records, and mandatory genetic testing      CR and O
       determine the potential impact of the   with relation to insurance, education, health
       proposal on life in the community       care, and employment.
       and the region
                                               Express educated opinions on the theological
H.12.3 Show* how policy decisions in           implications of genetic manipulatio n of            CR and O
       science depend on many factors,         organisms.
       including social values, ethics,
       beliefs, time-frames, and
       considerations of science and
       technology                              * All of these learning targets are associated
                                               with each standard.
H.12.5 Investigate* how current plans or
       proposals concerning resource
       management, scientific knowledge,
       or technological development will
       have an impact on the environment,
       ecology, and quality of life in a
       community or region




     Assessment Types:     SR = Selected Response (matching, multiple choice, T/F)        PA = Performance Assessment (performance or authentic tasks)           8
                           CR = Constructed Response (short answer/essay)                 O = Observation (interactive and non-interactive)
Course Title: Biotechnology                                       ECASD Curriculum Template                                       Date: November 2004
Subject: Life Science                                                    2004-05                                                  Grade Level: 10-12
Course Length: Semester

UNIT TITLE: (6) Ethical, Legal, and Social Implications of Biotechnology                         TIMELINE (LENGTH OF UNIT): 3 weeks
                                                                                                                                                Essential District
                                                                                                     Assessment              Essential
         Performance Standards                                 Learning Targets                                                                   Instructional
                                                                                                      Type(s)                Questions
                                                                                                                                                    Materials
G.12.5 Choose a specific problem in our         Research an ethical issue and prepare a           PA
       society, identify* alternative           persuasive essay or presentation to defend one
       scientific or technological solutions    side of that ethical issue.
       to that problem and argue its merits




      Assessment Types:     SR = Selected Response (matching, multiple choice, T/F)      PA = Performance Assessment (performance or authentic tasks)           9
                            CR = Constructed Response (short answer/essay)               O = Observation (interactive and non-interactive)