NIGMS MINORITY PROGRAMS NATIONAL UPDATE INSTITUTE OF GENERAL MEDICAL SCIENCES • WINTER 2003 INSIDE THIS ISSUE A B R C M S C O M M E M O R AT E S NIGMS Celebrates 40 Years of Discovery, Progress 4 NIGMS Anniversaries BY JILLIENE MITCHELL, NIGMS From the MORE Director: Undergraduate and graduate students, postdoctoral fellows, and faculty members came Taking the Risk Out from all over the country to attend the second Annual Biomedical Research Conference of Taking Risks 6 for Minority Students (ABRCMS), held November 13–16 in New Orleans, LA. Zlotnik Appointed The conference brought together MORE program participants, academic MBRS Director 7 administrators, grant ofﬁcials, and other members of the scientiﬁc community to hear research presentations; attend professional development workshops, Proﬁle: Nancy Urizar 8 poster sessions, and exhibits; and network with each other. The meeting also Research Highlight: marked the special occasion of the 40th anniversary of NIGMS and the 30th Study May Explain Fear anniversary of the Institute’s Minority Access to Research Careers (MARC) Response in PTSD 10 and Minority Biomedical Research Support (MBRS) programs. NIGMS Brochure Available 11 The anniversary events began with a panel discussion by two Nobel laureates and a scientist who has been described as a potential laureate in the future. News and Notes 12 Dr. Thomas R. Cech of the Howard Hughes Medical Institute and Dr. Alfred Selected Publications 16 G. Gilman of The University of Texas Southwestern Medical Center at Dallas discussed their Nobel-winning research and encouraged students to pursue Upcoming Meetings 17 research opportunities. Dr. Erich Jarvis of Duke University, an up-and-coming Recent Awards scientist who participated in the MARC and MBRS programs as an under- and Fellowships 18 graduate student at the City University of New York, Hunter College, described his research on vocal learning in birds. Jarvis’ honors include the prestigious Waterman Award from the National Science Foundation in 2002. Jarvis also participated in a panel discussion on the scientiﬁc accomplish- ments and career pathways of MARC and MBRS alumni. The other speakers were Dr. Juliette Bell of Fayetteville State University, Dr. Luis Haro of the University of Texas at San Antonio, Dr. Yolanda Sanchez of the University of Cincinnati, Dr. Michael Anderson of The Johns Hopkins University, and Dr. Scottie Henderson of the University of Arizona. The panelists shared their experiences and offered their advice to students. Phyllis Wilson, a senior Haro discussed the path that led him to a science career. Born into a family biology and pre-med major at Virginia State University, performs of migrant farm workers, he explained that he was the ﬁrst in his family to research in the university’s Bridges to the Baccalaureate lab. attend college. He realized that he wanted to become a scientist while he was For more on Wilson’s recent activi- ties, as well as those of other an undergraduate student participating in the MBRS program at the University NIGMS minority program partici- of California, San Diego (UCSD). pants, see the News and Notes section on page 12. continued on page 2 U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of General Medical Sciences 2 National Institute of General Medical Sciences continued from page 1 Anderson stressed the importance of having a mentor and emphasized that this was the most critical factor in helping him achieve his career goals. He urged students to ﬁnd mentors who have their best interests at heart and told the students that mentors “don’t necessarily have to look like you” to do this. The anniversary activities concluded with a banquet marking the 30th anniversary of the MARC and MBRS programs. In the keynote address, the Honorable Louis Stokes, a strong supporter of the programs during his tenure as a Congressman from Ohio, noted the importance of honoring the efforts of the individuals who helped create these programs. Stokes particularly commended the hard work of the late Dr. Geraldine Pittman Woods, who played a pivotal role in the development of several NIH minority programs, particularly MARC and MBRS. Stokes also urged students to help others in need. He encouraged the students to remember ABRCMS meeting participants had the opportunity to meet one that, as far back as 30 years ago when the MARC another and share their experiences. Nearly 1,000 students made oral and poster presentations at the meeting, representing nine and MBRS programs were developed, people were disciplines in the biomedical sciences. working to help underrepresented minority stu- dents pursue biomedical research careers. Geraldine Woods Award Established This year’s ABRCMS meeting marked the establishment of the Geraldine Woods Award, which recognizes individuals who have had a signiﬁcant impact in promoting the advancement of under- represented minorities in biomedical science. The ﬁrst recipients were three early advocates for The NIGMS Minority Programs NIGMS’ minority programs: the Honorable Louis Stokes, Dr. Ruth L. Kirschstein, and Dr. Charles Update is produced by the Ofﬁce of Communications and A. Miller. Public Liaison of the National Institute of General Medical Stokes was recognized for his support and ongoing commitment to the research training of Sciences. The material is not copyrighted and we encourage underrepresented minorities. Stokes’ efforts resulted in the creation of a number of NIGMS and its use or reprinting. NIH programs to support minority students and minority-serving institutions. Editor: Susan Athey Kirschstein, currently a senior advisor to the NIH director, previously served as the deputy direc- firstname.lastname@example.org tor of NIH. She was the director of NIGMS from 1974–1993, and she served as acting director of Editorial Assistant: Jilliene Mitchell NIH from 1999–2002. Kirschstein was cited for her leadership, dedication, and commitment to the email@example.com research training of underrepresented minorities while at the helms of NIGMS and NIH. Ofﬁce of Communications and Public Liaison, NIGMS Miller, a former director of what at the time was the NIGMS Cellular and Molecular Basis of Room 3AN.32 45 Center Drive MSC 6200 Disease Program Branch, was recognized for his work to encourage the research training of under- Bethesda, MD 20892-6200 represented minorities in the biomedical sciences. Miller served as a champion at NIH for such Tel: 301-496-7301 Fax: 301-402-0224 programs and led efforts to establish the MARC program at NIGMS. NIGMS Minority Programs Update WINTER 2003 3 “You have the same obligation…to not only achieve your career and do it with excellence, but Profiles of Excellence Available also at the proper point to reach back and help pull someone else up.” Dr. Marian Johnson-Thompson, director of education and biomedical research development ABRCMS attendees received a 16-page at the National Institute of Environmental Health booklet highlighting six successful MARC Sciences, paid further tribute to Woods, who was and MBRS programs and the accomplishments her mentor. of many current and former program partici- Dr. Clifton Poodry, director of the MORE pants. For free copies of the booklet, Proﬁles Division, said “The recognition of the contribu- of Excellence: MARC and MBRS Programs, tions of Geraldine Woods, with her family as contact: guests in the audience, was very moving for me.” Ofﬁce of Communications “If it weren’t for the efforts of Dr. Woods and and Public Liaison, NIGMS her colleagues, NIGMS’ minority programs Room 3AN.32 wouldn’t be the success that they are today. I am 45 Center Drive MSC 6200 proud we could honor such important individuals Bethesda, MD 20892-6200 as we marked the 30th anniversary of MARC and MBRS,” he added. h 301-496-7301 firstname.lastname@example.org More information on the 2003 ABRCMS meeting, which will be held October 15–18 in San Diego, CA, can be found on the ABRCMS meeting Web site at http://www.abrcms.org . Recipients of the Geraldine Woods Award (from left) the Honorable Louis Stokes, Dr. Charles Miller, and Dr. Ruth Kirschstein. 4 National Institute of General Medical Sciences NIGMS Celebrates 40 Years of Discovery, Progress BY ALISA ZAPP MACHALEK, NIGMS The year is 1962. John and MBRS—commemorated their 30th anniver- Glenn, Jr., becomes the saries in 2002. ﬁrst American to orbit the Training Tomorrow’s Scientists Earth, Sam Walton opens Since its inception, NIGMS has been dedicated the ﬁrst Wal-Mart, a ﬁrst- to teaching students how to become independent class stamp costs 4 cents, researchers. Nearly half of all NIH predoctoral and —most relevant trainees, and a large portion of postdoctoral here — NIGMS is created. trainees, receive their support from NIGMS. Established by Recognizing that the most signiﬁcant biomed- Congress to support ical investigations often involve and affect several research and training in different ﬁelds, the Institute designed its training the “general or basic med- programs to cut across disciplinary and depart- ical sciences,” NIGMS has mental lines. In addition, NIGMS has several a strong record of sup- programs that address areas of critical scientiﬁc porting scientists at the need. One of these, the Medical Scientist Training forefront of their ﬁelds. In Program, leads to a combined M.D.-Ph.D. degree its 40-year history, more and prepares scientists to bridge the gap between than 50 of its grantees basic and clinical research. Other programs train have won Nobel Prizes for scientists to conduct research in the rapidly growing their groundbreaking field of biotechnology and at the interface between research—including two chemistry and biology. The Institute also sponsors in 2002. a Pharmacology Research Associate Program—its Today, NIGMS has one Renee Hosang, a graduate student at Florida International only intramural activity—that trains postdoctoral University, beneﬁted from a MORE program. of the largest budgets at scientists in pharmacology in NIH and Food and NIH, coming in at more Drug Administration laboratories and clinics. than $1.7 billion. The Institute—which is almost entirely extramural— funds more than 4,000 Forging Paths into New Areas research grants to universities, medical schools, hos- In the late 1990s, NIGMS held meetings with pitals, and other research institutions. Its broad leaders of the scientiﬁc community to get interests lie in areas such as cell, molecular, develop- their advice and vision on new directions in mental and computational biology; genetics; science and the needs of researchers. A common chemistry; and pharmacology. Basic studies in these theme emerged: Solving many of the most and other areas covered by NIGMS increase our complex—and interesting—questions in biology understanding of life processes and lay the founda- requires interdisciplinary cooperation and tion for advances in disease diagnosis, treatment, multifaceted approaches. In response, NIGMS and prevention. established collaborative and integrative grants The Institute has a longstanding commitment (better known as “glue” grants) to bring together to increasing the number and competitiveness large groups of scientists from diverse ﬁelds to of minority biomedical and behavioral scientists. help tackle these complicated research problems. Through the MORE Division, NIGMS has helped Another area that beneﬁts from NIGMS’ thousands of minority students pursue degrees emphasis on collaboration is pharmacogenetics, in science and has enhanced research and training the study of how genes affect the way people at minority-serving institutions throughout respond to medicines. Already, more than a dozen the country. Adding to the air of celebration at NIGMS-sponsored research teams have begun NIGMS, both of MORE’s branches —MARC unraveling why the same dose of a drug can help NIGMS Minority Programs Update WINTER 2003 5 some people, have no effect on others, and NIGMS has also capitalized on harm a few. This knowledge can allow advances in genome sequencing through physicians to tailor the doses of certain its Protein Structure Initiative. Launched medications and save lives. in 2000, this project builds on the As part of its 40th anniversary The Institute recognizes that vast sci- Institute’s significant investment in celebration, NIGMS selected 40 entiﬁc treasures are hidden within the structural biology. The goal is to solve burgeoning masses of genome sequence the structures of 10,000 genetically topics that reflect its interests and and other biological data. To mine these unique proteins in 10 years, enabling accomplishments. Brief descriptions will require quantitative tools and scientists to produce an inventory of all approaches. Beginning in 1998, NIGMS the shapes that proteins can take in nature. and illustrations of these topics created a set of initiatives to encourage This, in turn, will help make it possible are at http://www.nigms.nih.gov/ mathematicians, physicists, computer to predict the structure of any protein scientists, and engineers to apply their based on its sequence. anniversary/discovery/. expertise to biomedical research. In 2001, To further advance the field of to serve as the focal point for such activi- molecular structure determination, ties, NIGMS created its newest component, NIGMS funds the cutting-edge equip- the Center for Bioinformatics and ment and facilities necessary for these Computational Biology. studies. In recent years, the Institute continued on page 11 Banking on Cells In 2002, NIGMS also celebrated the 30th anniversary of the Human Genetic Cell Repository, which plays a vital role in genetics research. Maintained by the Coriell Institute for Medical Research in Camden, NJ, the repository houses the world’s largest collection of human cell cultures. It contains nearly 8,000 high- quality cell lines and DNA samples from people with various genetic disorders, their family mem- bers and unaffected people whose cells can be used as controls. (Strict policies ensure informed consent and conﬁdentiality.) Every week, the repository ships about 100 cell lines and 1,000 DNA samples to scientists from any of 60 countries. Cell cultures from the repository have already aided discovery of the genes associated with hun- dreds of diseases, including cystic ﬁbrosis, Huntington’s disease and retinitis pigmentosa. Repository materials are used extensively in studies of gene expression and mutagenesis, as well as in studies such as the HapMap project, which seeks to identify patterns of human gene variation. Inform- ation on the repository is available at At the Coriell Repository tank room, cells are stored in liquid nitrogen and are preserved http://locus.umdnj.edu/nigms. h virtually indeﬁnitely. 6 National Institute of General Medical Sciences FROM THE MORE DIRECTOR Taking the Risk Out of Taking Risks BY CLIFTON POODRY, PH.D. Directors of training grants or other student development likely to succeed. In such a case, the value of giving programs want to have superior outcomes to show for someone a chance is outweighed by the value of their efforts, especially when the time comes to submit avoiding failure. a grant renewal application. The obvious, “risk- Assuming that we want to reap the potential averse” approach is to select students who appear beneﬁts of accepting into our programs students to be the most likely to succeed. However, by doing who have unorthodox credentials, are there ways so, we reduce the size and diversity of the pool by to minimize the risk of taking risks? I believe so, not accepting students with different credentials provided that three elements are in place: who may be capable of making major contribu- • a plan to provide assistance; tions to science. What strategy would minimize • a clear measure of accomplishments; and the risk and optimize the success of a program • a set of alternatives if satisfactory progress that is willing to accept the latter type of student? is not being made. As a scientist whose career started when a In order to provide the most effective assis- professor was willing to take a risk on me as a grad- tance, it is necessary to determine the initial skill uate student, I have a bias in favor of thinking levels of the applicant and develop a plan for broadly and boldly when considering students for guiding needed improvements. Is the applicant admission to graduate programs. My a self-learner and a self-starter? Does he or she undergraduate grade point average was possess good critical-thinking skills? Is the appli- just that—average. I am fortunate that cant’s background knowledge well-rounded? a program took a risk in admitting me Does he or she have good communication skills? (and supporting me on an NIH training These and similar questions will help identify a grant). Years later, I asked my graduate student’s relevant strengths and weaknesses and advisor why he had taken a chance on me. guide the development of an individually tailored His response was that I had earned 98th course of study. and 99th percentiles on the GRE and In order to ensure that progress is being made, As in organic chemistry and genetics. take periodic measures of the student’s skills to He ﬁgured that my being a football provide individualized, constructive feedback and player as an undergraduate might have impacted reinforcement. my grades. He also saw that I was successfully If a program takes risks, there will be a certain completing a master’s degree with no scholarship amount of fallout. Conscientious career guidance support (I took out loans). can help mitigate the trauma of failure and the The notion of risk is very subjective. It involves distress this causes to the entire program. When an interplay between the probability that an adverse students have multiple options before them, they event will occur and the severity of its perceived will see that many paths can lead to success as consequences. There are high ﬁnancial stakes long as they utilize their energy and talents. I knew when funds are committed to supporting a student that with my master’s degree I could become a for multiple years, which must be weighed against high school science teacher, which was a whole lot the risk of accepting a student who might not better than some other jobs I could imagine. One of complete the course of study. Perhaps more impor- the great skills of my advisor/mentor was his tant, the failure of a student is often traumatic and enthusiastic support that instilled self-conﬁdence. demoralizing, not only to the student and his or her He helped people see where they could make the advisor, but to the whole department. The risk of best match between their dreams and realities. He that trauma is reason enough for some to err on did this for everyone—from students to techni- the side of selecting only those students who are cians to postdocs—without passing judgment, NIGMS Minority Programs Update WINTER 2003 7 guiding individuals to their own decisions. He was credentials of the graduating class? I invite your taking risks, but calculated ones—he was admitting comments and suggestions on how the “value-added” students of varying background levels and variable aspects of a program could be evaluated and how career trajectories, then helping them to become risk-taking could be addressed in review and award successful. criteria. h How can programs look beyond the “risk-free” student pool and take calculated risks with some Dr. Clifton Poodry, email@example.com, students who have unconventional, but potentially Director, MORE Division, NIGMS, Room 2AS.37, valuable backgrounds? Should the quality of our 45 Center Drive MSC 6200, Bethesda, MD 20892-6200, training programs be judged on more than the 301-594-3900 high credentials of the incoming class and the high Zlotnik Appointed MBRS Director BY SUSAN ATHEY, NIGMS Dr. Hinda Zlotnik, a microbiologist with extensive Universidad Nacional Autónoma de experience in grant and program administration, has México in Mexico City, and her Ph.D. been appointed chief of the MBRS Branch at NIGMS. in microbiology and immunology from Zlotnik had been working as a program director Temple University in Philadelphia. in the MORE Division since 1999. She came to She did postdoctoral work at Temple NIGMS from the University of Puerto Rico School University’s Skin and Cancer Hospital, of Medicine in San Juan, where she was director of as well as at the National Institute of the Ofﬁce of Sponsored Research and a professor in Diabetes and Digestive and Kidney the department of microbiology and medical zoology. Diseases’ (NIDDK) Laboratory of During her academic tenure, Zlotnik’s research Enzymes and Biochemistry. In 1995, focused on pathogenic actinomycetes (bacteria she spent 6 months as an NIH extramu- related to those that cause strep infections). In addi- ral associate, performing assignments tion, she was active in training underrepresented with the MARC Branch and with the minority students for careers in science, a major National Institute on Deafness and aim of the MORE Division. Other Communication Disorders. “Dr. Zlotnik brings a solid science background Zlotnik is a member of several scien- Dr. Hinda Zlotnik and a sensitivity to the needs and concerns of the tiﬁc societies, including the American grantee community,” said Dr. Clifton Poodry. “She Association for the Advancement of Science, has earned the respect of colleagues here at NIH as the American Society for Microbiology, the well as from the directors of MORE programs International Society for Human and Animal across the country.” Mycology, and the Medical Mycological Society of Zlotnik succeeds Dr. Ernest Márquez, who the Americas. She served as president of the Puerto directed the MBRS Branch from 1996–2002 and Rico Society of Microbiologists from 1991–1992 who is now associate director for special popula- and editor of the Medical Mycological Society of the tions at the National Institute of Mental Health. Americas newsletter from 1994–1997. h Zlotnik earned her undergraduate degree in biochemistry and microbiology from the 8 National Institute of General Medical Sciences Proﬁle NANCY URIZAR This section proﬁles former MORE other schools, Urizar did not get into participants who have excelled in their Baylor, which was her top choice. ﬁelds. We hope that the proﬁles will give Determined to go there, she continued students an idea of the types of careers working as a lab assistant at Baylor and available with science degrees and the paths then reapplied for admission. She was others have taken to achieve those careers. accepted the following year. In addition to her strong will and A Bright Future for an Aspiring determination, Urizar attributes much of Scientist her success to the MBRS program, which BY JILLIENE MITCHELL, NIGMS provided her with ﬁnancial assistance and “ I became interested in science after taking offered her the chance to go to meetings a high school biology class,” said Nancy such as the Gordon Research Conference Urizar, a graduate student at Baylor on Hormone Action, which she attended College of Medicine in Houston, Texas. during her ﬁrst year of graduate school. “The instructor’s enthusiasm for sci- “The Gordon Conference gave me the ence led me to value both scientists and opportunity to meet many well-known scientiﬁc discovery,” she added. scientists,” Urizar said. “Seeing their excel- Urizar recalls seeing the inside of a lab lent research motivated me to work even for the ﬁrst time on a high school ﬁeld harder,” she added. “If you reach a point where something is not trip to Baylor. This experi- Urizar also attributes her success to working after more than three or four tries, go ence helped inspire her to having a good mentor, Dr. David D. and get help from an expert in that technique.” pursue a scientiﬁc career Moore. She currently works in his lab in and later prompted her to the department of molecular and cellular choose Baylor for graduate school. biology, studying the role that FXR, a type Encouraged by her parents to stay in of protein called a nuclear hormone the Houston area, Urizar received her receptor, plays in maintaining the balance undergraduate education at the University of lipids in the body, especially cholesterol of Houston on a full scholarship. She got levels. Urizar was the ﬁrst author on a hands-on laboratory experience working paper in Science identifying a natural part-time as a laboratory assistant at product that lowers cholesterol levels in an Baylor. animal model (see the full citation in the Urizar earned a bachelor’s degree in Selected Publications section). This work biochemistry, but she knew that she received international attention. wanted to further her education. After Urizar credits Moore with helping her taking a year off from school, she applied to become an independent researcher. to several graduate schools, including “When I go to Dr. Moore for help, he Baylor. Although she was accepted into doesn’t simply tell me what to do. Instead 8 NIGMS Minority Programs Update WINTER 2003 9 he and I discuss ways to solve the prob- “I just have to ﬁnd the career that’s lem,” she explained. perfect for me,” she said. h Urizar advises students entering graduate school to seek assistance from If you know an outstanding former advisors, instructors, postdocs, and other MARC, MBRS, or Bridges participant who students. has excelled professionally and you would “If you reach a point where something like to nominate that person as a future is not working after more than three or Update proﬁle subject, please let us know. four tries, go and get help from an expert Your suggestions are always welcome. in that technique,” Urizar said. Although uncertain of the direction she wants to take in the future, Urizar knows she wants a career in science. Nancy Urizar (right) performs research with postdoctoral fellow Wendong Huang (left) and graduate student Jun Zhang in her lab at Baylor College of Medicine. 10 National Institute of General Medical Sciences RESEARCH HIGHLIGHT Study May Explain Fear Response in PTSD Nearly all of us have had a traumatic experi- instead generates a new safety memory to lated the prefrontal cortex in rats that had ence at some point in our lives, but most of us block the fear response. According to this never exhibited extinction and paired the can move on and go about our daily business. theory, some part of the brain must create stimulation with the sound, the stimulated People with post-traumatic stress disorder the safety memory by increasing its activ- rats displayed little fear, acting as if their (PTSD), however, experience recurrent ity after extinction. In the November 7, fear response had been erased. Later, these fear and anxiety that never seems to go 2002, issue of the journal Nature, Milad rats continued to be unafraid of the sound away, even long after the traumatic event and Quirk showed for the ﬁrst time that even without stimulation. is over. An MBRS-supported researcher in nerve cells in the prefrontal cortex What could be going on? Puerto Rico was part of a team that iden- increased their activity in response to the The researchers speculate that since tiﬁed one area of the brain that may be sound only after extinction, creating what the prefrontal cortex sends signals to the essential for learning how not to be afraid. the researchers called a “safety signal.” amygdala, which is a cluster of nerve cells The researchers suggest that people with The team found that the more active this in the brain that stores memories, includ- PTSD may have impaired function in the brain region was, the less afraid the rats ing those of fear, stimulating the front part of the brain, called the pre- were when they heard the sound. The rats prefrontal cortex may directly impact frontal cortex. with the most prefrontal cortex the ability to remember a fear response. MBRS researcher Dr. Gregory Quirk activity acted as if they had never been The ﬁndings also suggest the exciting and graduate student Mohammed Milad conditioned to fear at all. The scientists’ possibility that stimulating the prefrontal at the Ponce School of Medicine have findings lend support to the idea that cortex could someday be used to strengthen studied this area of the brain by recording fear reduction is an active process. the extinction response in people with electrical activity in the prefrontal cortex Milad and Quirk, who both receive anxiety disorders. h of laboratory rats. The team conditioned funding from the National Institute of the rats to fear a sound the scientists Mental Health, did more experiments Reference: Milad MR, Quirk GJ. Neurons played while delivering a foot shock to with the rats and learned that stimulating in medial prefrontal cortex signal memory the rats. They measured fear by the degree one particular region of the prefrontal for fear extinction. Nature 2002;420:70-4. to which the rats became immobilized, cortex diminished the rats’ fear response. known as the freezing response. Repeated When the researchers electrically stimu- Research Highlights features the research presentations of the sound without the being done by current and former students shock caused fear responses to slowly and faculty in the MARC, MBRS, and disappear, a process researchers call other NIGMS minority programs. We extinction of the response. welcome your story ideas and suggestions Classic behavioral experiments for future Research Highlights items. dating back to Pavlov’s dogs have suggested that extinction does not erase a fear association from memory, but NIGMS Minority Programs Update WINTER 2003 11 continued from page 5 has supported construction of the most For 40 years, NIGMS has been at the powerful NMR magnets available (900 leading edge of supporting this progress. As MHz) and, together with the National it continues to champion basic research, Cancer Institute, it is funding the design to train future scientists, and to forge and construction of three beamlines at paths into new areas, its future promises Argonne National Laboratory’s Advanced to hold even more exciting and signiﬁcant Photon Source, the newest and most advances. h advanced synchrotron in the country. A Bright Future “NIGMS is a very special organization, dedicated to the “ The most important biomedical expansion of knowledge that will lead to the prevention, questions today—how genes are regu- lated, how cells and organisms develop diagnosis, treatment and hopefully, cure, of diseases that and function, and what causes cellular still plague humankind. The institute is not only support- processes to go awry—have not changed much in the last four decades,” says ing research at the forefront of the biological sciences, Dr. Judith H. Greenberg, acting director it is also drawing in valuable perspectives of the chemical, of NIGMS. “But the level of detail at which we can answer these questions has physical, and mathematical sciences.” changed dramatically. This progress not —Dr. Ruth Kirschstein, Senior Advisor to the NIH Director, only helps us understand the biological basis of life, it has also been translated who directed NIGMS for 19 years (1974–1993) into new approaches to treating and preventing diseases.” NIGMS Brochure Available NIGMS recently published a new brochure titled From Molecules to Medicines: Research and Training Programs of the National Institute of General Medical Sciences. The booklet provides a brief overview of the Institute’s mission, including a list of key research areas supported by NIGMS and a sampling of research advances. The booklet is available online at http://www.nigms.nih.gov/moleculestomeds/. Free copies of the booklet can be requested by contacting: Ofﬁce of Communications and Public Liaison, NIGMS Room 3AN.32 45 Center Drive MSC 6200 Bethesda, MD 20892-6200 301-496-7301 firstname.lastname@example.org 12 National Institute of General Medical Sciences NEWS and Notes • Dr. N. Kent Peters and Dr. Brian Pike recently • Dr. Thomas Landefeld, the MARC and Bridges to joined NIGMS as scientiﬁc review administrators in the Baccalaureate program director at California State the Ofﬁce of Scientiﬁc Review, where they manage University, Dominguez Hills (CSUDH), received the the review of applications to the MORE Division as 2002 Society for Advancement of Chicanos and Native well as other selected grant applications. Americans in Science (SACNAS) Undergraduate Peters was formerly a program director for meta- Institution Mentor Award at the society’s annual meeting bolic biochemistry at the National Science Foundation. in September. The award recognizes individuals who Before that, he was a professor in the department of have dedicated themselves to science, education, and chemistry and biotechnology at the Agricultural mentoring and who serve as role models for the next University of Norway. He earned a bachelor’s degree generation of minority scientists. Landefeld is associate in biological sciences from Indiana University and dean of the College of Arts and Sciences and is a a Ph.D. in cellular and molecular biology from the professor of biology at CSUDH. University of Michigan. He conducted postdoctoral • Dr. Victoria Luine and Dr. Carol Woods Moore research at Stanford University. were honored as Outstanding Women Scientists in Pike was formerly a research assistant professor in November by the New York Metropolitan Chapter of the department of neuroscience at the University of the Association for Women in Science. Luine is a pro- Florida College of Medicine in Gainesville. He earned fessor of psychology and an MBRS program director a bachelor’s degree in psychology and a Ph.D. in bio- at the City University of New York (CUNY), Hunter logical psychology from Virginia Commonwealth College. Moore, a medical professor, is a principal University in Richmond. He conducted postdoctoral investigator on an MBRS grant at the Sophie Davis research in the department of neurosurgery at the School of Biomedical Education of the CUNY Medical University of Texas Health Science Center at Houston. School. Both were recognized for the exceptional qual- • Dr. Barry R. Komisaruk, a program director ity of their scientiﬁc research and for their outstanding in the NIGMS MORE Division, received a 2002 mentoring of women. National Role Model Mentoring Award. The award • Barry University in Miami Shores, FL, marked the was presented by Minority Access, Inc., a nonproﬁt 20th year of its MARC program with a research sym- educational organization that assists Federal agencies, posium at the university in February. The symposium universities, and corporations to improve their recruit- included research presentations by some of the 100- ment, retention, and training of minority researchers. plus current and past MARC students. For more on Komisaruk was cited for his 17 years of service on the symposium, see http://www.barry.edu/ NIGMS’ MBRS grant at Rutgers, The State University marcsymposium. of New Jersey. During his afﬁliation with the MBRS program at Rutgers, including 14 years as the grant’s • Participants in the American Indian/Alaska Native principal investigator, Komisaruk mentored more than Bridges to the Doctorate program at the University of 100 minority students. Minnesota-Twin Cities met in October for their Komisaruk was among 10 individuals selected for second annual project retreat. The retreat featured a mentoring role model award. He received the award student and faculty research focused on Indian health. during a ceremony at the National Role Models This Bridges program provides both cultural and Conference in Washington, DC, in September. academic support to students pursuing a Ph.D. in nursing. NIGMS Minority Programs Update WINTER 2003 13 • Sederick C. Rice, a former MBRS program partici- Three MBRS program participants at the pant at the University of Arkansas at Pine Bluff University of California, San Francisco (UCSF), (UAPB), was selected as one of Ebony magazine’s received doctoral degrees during spring and summer “Young Leaders of the Future.” Rice was featured in the commencement ceremonies. Abraham Anderson magazine’s February issue among the top 30 individu- received a Ph.D. in bioengineering and is now a bio- als aged 30 and younger who have “excelled in sports, informatics scientist at Torrey Mesa Research Institute the arts, religion, medicine, business, and education.” in San Diego; Keith Reiling received a Ph.D. in Rice earned his bachelor’s degree in biology from biophysics and is performing postdoctoral research UAPB in 1994. He went on to earn a master’s degree in at the University of California, Berkeley; and biology from Delaware State University in 1996, and is Christopher Reyes received a Ph.D. in biophysics currently pursuing his Ph.D. in the department of pedi- and is performing postdoctoral research at UCSD. atrics at UVM’s College of Medicine. Rice’s research Two former MBRS program participants at focuses on the genetic effects of chemotherapy in chil- Chicago State University who received Ph.D.s are dren with acute lymphocytic leukemia. Reginald Teverbaugh, whose Ph.D. in chemistry is from Northwestern University, and Chris • Among the student participants in NIGMS’ minor- Withers, whose Ph.D. in physics is from the ity programs who earned degrees recently are: University of Miami. Seven MARC undergraduate students at Delaware Angela Erazo and Kester K. Haye, both MARC State University received their bachelor’s degrees in undergraduate students at CUNY, Brooklyn College, May and entered Ph.D. programs with scholarships received bachelor’s degrees in biology this past June. this fall. Denise Davis received a degree in biology and is attending Yale University; Patrice Green received a • Many participants in NIGMS’ minority programs degree in physics with an engineering emphasis and is spent the summer of 2002 performing research away attending the University of Delaware; Yvette Green from their home institutions. The participants and received a degree in biology and is attending Rutgers, their summer institutions are listed below, grouped by The State University of New Jersey/The University of home institution: Medicine and Dentistry of New Jersey; Shari Lee Barry University: Maria Abreu, Baylor College received a degree in biology and is attending the of Medicine; Constanza Berger, Western Kentucky University of Pennsylvania; Darius Sanders received University; Eauly Brautigam, University of Maryland, a degree in physics with an engineering emphasis and Baltimore County (UMBC); Melanie Camacho, is attending Virginia Polytechnic Institute and State Emporia University; Nikeisha Chin, Colorado State University; Melissa Tamburo received a degree in University; Paola Colmenares, University of the West psychology and is attending Rutgers, The State Indies, Jamaica; Dominique Florville, University of University of New Jersey; and Aaron Williams California, Los Angeles (UCLA); Empress Hughes received a degree in physics and is attending North and Nahshan St. Bernard, The Hormone Research Carolina State University. Center, Korea; Ivette Lopez, University of Miami; Two MBRS program participants at CUNY Raquel Peralta, Mt. Sinai School of Medicine; received doctoral degrees in biology. They are Angel Kevin Peterson and Amber Siler-Knogl, Columbia Pimentel, who attended City College, and Melania University; Roody Pierre-Charles, Stazione Zoologica, Mercado Pimentel, who attended City College and Italy; Erica Ramos, Northern Arizona University; Lehman College. Both began postdoctoral fellowships continued on page 14 at the University of Arizona in September. 14 National Institute of General Medical Sciences continued from page 13 Dick Salihah, Cornell University; Christina Coca-Cola Company, Atlanta; Shylise Grifﬁths and Stujenske, California Institute of Technology; Franki Faulkner, University of North Carolina at Florence Taylor, University of California, Berkeley; Chapel Hill; and LaKisha Partman, University of and Gesulla Toussaint, University of Florida. South Carolina. Chicago State University: Keyona Fletcher, University of Arizona, Tucson: Irene Alvarez, University of Michigan; Jeremy Harrison, Purdue National Heart, Lung, and Blood Institute, NIH; Alex University; Kara Scott, University of Alabama; Corpia Barela, NIDDK, NIH; Nanibaa Garrison, Pasteur Smith, Chicago State University; Stephen Smith, Institute, Paris, France; Linda Mobula, The Johns University of California, Berkeley; and Tiffany White, Hopkins University; Humberto Sirvent, University Northwestern University. of Notre Dame; and Jennifer Thompson, UCSD. CUNY, Brooklyn College: Allyson Bunbury, UCLA: Charisse Crenshaw, University of National Institute on Aging, NIH; Tamara Edwards, Florence, Italy. Rutgers, The State University of New Jersey; Ismaele Virginia State University: Phyllis Wilson, Jacques, Weill Medical College of Cornell University; Strategic Petroleum Reserve, New Orleans. Ufeta Om’Iniabohs, UCSD; and Shella Saint Fleur, • The following participants in NIGMS’ minority Harvard Medical School. programs made presentations about their research at CUNY, Hunter College: Ten MARC and MBRS recent scientiﬁc meetings: students participated in the Hunter College/Columbia Benedict College: MBRS program participants University Health Sciences summer research program. Nafeesa Ahamed, Shannel MacKall-Moore, and They are Lauriaselle Afanador, Jeanne Amuta, Jayson Ndiya Ogba presented at the 2002 Annual Meeting Bastien, Alain Berthold, Candice Etson, Lavonne of the South Carolina Alliance for Minority People Hunter, Randy Jackson, Sidonie Jones, Tracy in Columbia, SC, in August. Robinson, and Julane Thompson. CSUDH: MARC undergraduate students Bernice Delaware State University: Diana Ackah, Yale Aguilar, Ibette Lemus, Jerome Nwachukwu, and University; Joyce Addo, Joel Copper, Michele LaMarr, Susana Rodriguez presented at the SACNAS annual and Jenel Nixon, University of Pennsylvania; Anthea meeting in September. Jerome Nwachukwu presented Aikins, Carrie Belﬁeld, Jeniter Hughes, and Rozie at the XIII Undergraduate Research Symposium in Townsend, University of Virginia; David Charlot, Puerto Rico in October. Dr. Thomas Landefeld, the College of William and Mary; Mastingor Desir, MARC program director at CSUDH, served as the University of Miami; Tiffany Hawkins, UCSF; Dorcey meeting’s keynote speaker. Jones, Harvard Medical School; Donté Jones and Medgar Evers College-Kingsborough Community Victoria Williams, Rutgers, The State University of College: Bridges to the Baccalaureate program partici- New Jersey; Emeka Omereh, University of Delaware; pants Sherise Warner, Shawlorna Morris, Kawasi Meron Solomon, Cornell University; Alicia Sherrell, Lett, Turkesha Huggins, Candice King, and Ayodeji UMBC; Dara Waiters, Brown University; KaTonna Nicholson presented at the 35th annual Metropolitan Williams, The Johns Hopkins University; and Jessica Association of College and University Biologists Witherspoon, Stanford University. Conference in October. Jefferson State Community College: Bridgett North Carolina A&T State University: MARC Hill, University of Alabama at Birmingham. students Shylise Grifﬁths, Manza Atkinson, Jennifer North Carolina A&T State University: Manza Davis, LaKisha Partman, and Franki Faulkner Atkinson, University of Iowa; Jennifer Davis, The NIGMS Minority Programs Update WINTER 2003 15 NIGMS Minority Programs Update WINTER 2003 15 presented at the First Annual North Carolina Alliance participant at the University of Texas at San Antonio, is to Create Opportunity Through Education Conference, now an assistant professor of ophthalmology at UCLA held in September on the campus of North Carolina • Liz Reynoso Paz, a former MARC trainee at SJSU, State University. received her Ph.D. in immunology from the University of California, Davis. She plans to start her own biotech • In recent months, we have received word about the company after completing postdoctoral work at the following current and former student participants in university • Elizabeth B. Torres, a former MARC NIGMS minority programs • Sherrice Allen, Sue trainee at SJSU, received her Ph.D. in cognitive science Carson, and Roberto Frontera-Suau, former partici- from UCSD and is now completing a postdoctoral pants in the Institutional Research and Academic fellowship at the California Institute of Technology. h Career Development Award program at the University of North Carolina at Chapel Hill, have gone on to fac- We are always interested in hearing about NIGMS ulty positions. Allen is a botany instructor at North minority program faculty, alumni, and students. Carolina State University, Carson is an assistant profes- Photographs of your students, research labs, and sor of biology at Fayetteville State University, and activities are also welcomed and encouraged. Frontera-Suau is an assistant professor of biology at Please send information to: Elizabeth City State University • Cheryl Anderson, Editor a former MBRS program participant at the University NIGMS Minority Programs Update of Washington in Seattle, is an assistant professor of Room 3AN.32 epidemiology at the University of Pennsylvania School 45 Center Drive MSC 6200 of Medicine • Diana M. Avila, a former MARC Bethesda, MD 20892-6200 trainee at St. Mary’s University and MARC predoctoral fellow at the University of Texas Health Science Center Tel: 301-496-7301 at Dallas, has joined the faculty of St. Mary’s University Fax: 301-402-0224 as an assistant professor in the department of bio- email@example.com logical sciences • Carol Bristol, a former MARC participant at CUNY, Brooklyn College, graduated with a bachelor’s degree in psychology in June 2000 and is in her second year of studies for an M.P.H. degree at George Washington University • Alexis Epps, an MBRS program participant at the University of Missouri-Columbia, has received a fellowship from the National Science Foundation/Missouri Alliance for Graduate Education and the Professoriate. The award will provide Epps with 5 years of support to pursue a doctoral degree in parasitology at the univer- sity • Julio C. Gonzalez, a former MARC trainee at San Jose State University (SJSU), earned an M.D.- Ph.D. from the University of Michigan and is now a fellow in the department of infectious diseases at the University of Washington Medical Center-Roosevelt • Nathan Mata, a former MBRS and MARC program 16 National Institute of General Medical Sciences S E L E C T E D P U B L I C AT I O N S by MORE Faculty and Students (listed by institution) UNIVERSITY OF ARIZONA Yaspelkis BB III, Singh MK, Trevino B, NORTH CAROLINA A&T STATE UNIVERSITY Kavarana MJ, Trivedi D, Cai M, Ying J, Krisan AD, Collins DE. Resistance Sappington PL, Yang R, Yang H, Tracey Hammer M, Cabello C, Grieco P, Han G, training increases glucose uptake and KJ, Delude RL, Fink MP. HMGB1 B box Hruby VJ. Novel cyclic templates of transport in rat skeletal muscle. Acta increases the permeability of caco-2 ente- alpha-MSH give highly selective and Physiol Scand 2002;175:315–23. rocytic monolayers and impairs intestinal potent antagonists/agonists for human barrier function in mice. Gastroenterol CHICAGO STATE UNIVERSITY melanocortin-3/4 receptors. J Med Chem 2002;123:790–802. Erhart MA, Lekgothoane S, Grenier J, 2002;45:2644–50. Nadeau JH. Pattern of segmental UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL Quinones HI, List AF, Gerner EW. Selective recombination in the distal inversion Canman JC, Sharma N, Straight A, exclusion by the polyamine transporter as of mouse t haplotypes. Mamm Genome Shannon KB, Fang G, Salmon ED. a mechanism for differential radioprotec- 2002;13:438–44. Anaphase onset does not require the tion of amifostine derivatives. Clin Cancer microtubule-dependent depletion of CITY UNIVERSITY OF NEW YORK, YORK COLLEGE Res 2002;8:1295–300. kinetochore and centromere-binding Rockhill RL, Daly FJ, MacNeil MA, Brown proteins. J Cell Sci 2002;115:3787–95. Reed C, Sturbaum GD, Hoover PJ, Sterling SP, Masland RH. The diversity of ganglion CR. Cryptosporidium parvum mixed cells in a mammalian retina. J Neurosci Hammond L, Castanotto D, Rice SR, genotypes detected by PCR-restriction 2002;22:3831–43. Nimgaonkar VL, Wirshing DA, Rossi JJ, fragment length polymorphism analysis. Heston LL, Sobell JL. Alteration of branch Rosenthal BS, Wilson WC. Relations of Appl Environ Microbiol 2002;68:427–9. site consensus sequence and enhanced psychological distress with objective pre-mRNA splicing of an NMDAR1 Saengsirisuwan V, Perez FR, Kinnick TR, individual, family, and neighborhood intron not associated with schizophrenia. Henriksen EJ. Effects of exercise training characteristics of urban adolescents. Am J Med Genet 2002;114:631–6. and antioxidant R-ALA on glucose trans- Psychol Rep 2002;90:371–86. port in insulin-sensitive rat skeletal Shannon KB, Canman JC, Salmon ED. UNIVERSITY OF THE DISTRICT OF COLUMBIA muscle. J Appl Physiol 2002;92:50–8. Mad2 and BubR1 function in a single Choudhary MA, Mazhar M, Ali S, Song X, checkpoint pathway that responds to a loss BARRY UNIVERSITY Eng G. Synthesis, characterization, and of tension. Mol Biol Cell 2002;13:3706–19. Lee JM, Petrucelli L, Fisher G, Ramdath S, biological activity of dimethyltin dicar- Castillo J, Di Fiore MM, D’Aniello A. boxylates containing geranium. Metal Shannon KB, Salmon ED. Chromosome Evidence for D-aspartyl-beta-amyloid Based Drugs 2002;8:275–81. dynamics: new light on aurora B kinase secretase activity in human brain. J function. Curr Biol 2002;12:R458–60. Eng G, Desta D, Biba E, Song X, May L. Neuropathol Exp Neurol 2002;61:125–31. Speciﬁcation of some triorganotin com- Thompson JT, Kier WM. Ontogeny of BAYLOR COLLEGE OF MEDICINE pounds in sediments from the Anacostia squid mantle function: changes in the Urizar NL, Liverman AB, Dodds DT, Silva and Potomac Rivers, Washington, DC, mechanics of escape-jet locomotion in the FV, Ordentlich P, Yan Y, Gonzalez FJ, using Mössbauer spectroscopy. Appl oval squid, Sepioteuthis lessoniana lesson. Heyman RA, Mangelsdorf DJ, Moore DD. Organomet Chem 2002;16:67–71. Biol Bull 2002;203:14–26. A natural product that lowers cholesterol Song X, Cahill C, Eng G. Crystal structure Wilkins HR, Ohneda K, Keku TO, D’Ercole as an antagonist ligand for FXR. Science of triphenyltin 4-methoxybenzoate. Main AJ, Fuller CR, Williams KL, Lund PK. 2002;296:1703–6. Group Metal Chem 2002;25:177–8. Reduction of spontaneous and irradiation- CALIFORNIA STATE UNIVERSITY, NORTHRIDGE induced apoptosis in small intestine of IGF-I Song X, Cahill C, Eng G. The crystal Yaspelkis BB III, Saberi M, Singh MK, transgenic mice. Am J Physiol Gastrointest structure of tricyclohexyltin N-n-butyl Trevino B, Smith TL. Chronic leptin treat- Liver Physiol 2002;283:G457–64. dithiocarbamate. Main Group Metal ment normalizes basal glucose transport in Chem 2002;25:13–4. a ﬁber type-speciﬁc manner in high-fat-fed rats. Metabolism 2002;51:859–63. NIGMS Minority Programs Update WINTER 2003 17 Williams KL, Fuller CR, Fagin J, Lund PK. of terpenylnaphthoquinones. Toxicol pathway for visual-pigment regeneration Mesenchymal IGF-I overexpression: 2002;175:167–75. in daylight. Neuron 2002;36:69-80. paracrine effects in the intestine, distinct Montanez-Clemente I, Alvira E, Macias YALE UNIVERSITY SCHOOL OF MEDICINE from endocrine actions. Am J Physiol M, Ferrer A, Fonceca M, Rodriguez J, Dragon F, Gallagher JE, Compagnone- Gastrointest Liver Physiol Gonzalez A, Barletta G. Enzyme activa- Post PA, Mitchell BM, Porwancher KA, 2002;283:G875–85. tion in organic solvents: co-lyophilization Wehner KA, Wormsley S, Settlage RE, PONTIFICAL CATHOLIC UNIVERSITY of subtilisin Carlsberg with methyl-β- Shabanowitz J, Osheim Y, Beyer AL, Hunt OF PUERTO RICO cyclodextrin renders an enzyme catalyst DF, Baserga SJ. A large nucleolar U3 Hales NW, Yamauchi K, Alicea A, more active than the cross-linked enzyme ribonucleoprotein required for 18S ribo- Sundaresan A, Pellis NR, Kulkarni AD. crystals. Biotechnol Bioeng somal RNA biogenesis. Nature A countermeasure to ameliorate immune 2002;78:53–9. 2002;417:967–70. dysfunction in in vitro simulated STATE UNIVERSITY OF NEW YORK, Wehner KA, Gallagher JE, Baserga SJ. microgravity environment: role of COLLEGE AT OLD WESTBURY Components of an interdependent unit cellularnucleotide nutrition. In Vitro Cell Hoyte RM, Zhang JX, Lerum R, Oluyemi within the SSU processome regulate and Dev Biol Anim 2002;38:213–7. A, Persaud P, O’Connor C, Labaree DC, mediate its activity. Mol Cell Biol PRAIRIE VIEW A&M UNIVERSITY Hochberg RB. Synthesis of halogen- 2002;22:7258–67. Harris G, Doctor VM. The effect of 6- substituted pyridyl and pyrimidyl deriva- aminohexanoic acid and fucoidan on the tives of [3,2-c]pyrazolo corticosteroids: Send in your references for inclusion activation of glutamic plasminogen by strategies for the development of gluco- in Selected Publications. We would streptokinase. Blood Coagulation & corticoid receptor mediated imaging appreciate your contribution to this Fibrinolysis 2002;13:355–9. agents. J Med Chem 2002;45:5397–405. section in order to represent as many MARC and MBRS programs as possible. UNIVERSITY OF PUERTO RICO, HUMACAO UNIVERSITY OF TEXAS AT SAN ANTONIO Complete bibliographical citations can be Alegria AE, Cordones E, Santiago G, Mata NL, Radu RA, Clemmons RS, Travis phoned, faxed, mailed, or e-mailed to the Marcano Y, Sanchez S, Gordaliza M, GH. Isomerization and oxidation of vita- Editor (see page 2). Martin-Martin ML. Reductive activation min A in cone-dominant retinas: a novel UPCOMING Meetings APRIL MAY JUNE 11–15, 2003 18– 22, 2003 12–18,2003 FEDERATION OF AMERICAN SOCIETIES AMERICAN SOCIETY FOR MICROBIOLOGY MORE PROGRAM DIRECTORS’ MEETINGS FOR EXPERIMENTAL BIOLOGY 103RD GENERAL MEETING June 12–14 BRIDGES MEETING EXPERIMENTAL BIOLOGY 2003 Washington Convention Center June 15–18 MARC/MBRS MEETING San Diego Convention Center Washington, DC Granlibakken Conference Center San Diego, CA CONTACT: ASM Lake Tahoe, CA CONTACT: Ofﬁce of Scientiﬁc Meetings 1752 N Street, NW CONTACT: MORE Division, NIGMS and Conferences Washington, DC 20036 45 Center Drive MSC 6200 9650 Rockville Pike Tel: 202-942-9356 Bethesda, MD 20892-6200 Bethesda, MD 20814-3998 firstname.lastname@example.org Tel: 301-594-3900 Tel: 301-530-7010 http://www.asmusa.org http://www.nigms.nih.gov/minority email@example.com http://www.faseb.org 18 National Institute of General Medical Sciences RECENT Awards and Fellowships PREDOCTORAL FELLOWSHIPS Nicholas J. Heredia Kara A. Porwancher Jason Watts North Carolina Central FOR MINORITY STUDENTS University of California, Yale University, University of Pennsylvania, University, Durham (listed by fellow and Los Angeles New Haven, CT Philadelphia Allyn Howlett graduate institution) Judith Jimenez Herson I. Quinones BRIDGES TO THE FUTURE University of Georgia, Ana R. Adham University of California, University of Texas AWARDS Athens Rice University, Houston, TX Irvine Southwestern Medical (listed by institution and Anthony C. Capomacchia Center at Dallas principal investigator) Brittnaie J. Bell Francis S. Kinderman MBRS RISE AWARDS University of South Carolina, University of California, Amy C. Raymond Bridges to the Baccalaureate (listed by institution and Columbia San Diego San Diego State University, principal investigator) California State University, CA Ma Margie Borra Kelly M. Kitchens San Marcos California State University, Oregon Health and Science University of Maryland, Carmencita Rojas-Cartagena Victor Rocha Hayward University, Portland Baltimore County Ponce School of Medicine, Maria C. Nieto Francis Marion University, Puerto Rico Mark Del Campo Vanessa A. Koelling Florence, SC Dull Knife Memorial College, University of Miami, FL University of Georgia, Jan Antoinette Romero Julia E. Krebs Lame Deer, MT Athens University of Pennsylvania, Robert R. Madsen Nikki A. Delk Harold Washington College, Philadelphia Rice University, Houston, TX . Bradford P Mallory Chicago, IL Turtle Mountain Community Cincinnati Children's Hospital Celeste A. Roney Uthman O. Erogbogbo College, Belcourt, ND Emily Derouen Medical Center, OH University of Texas Charmane F. Disrud Yeshiva University, New James Madison University, Southwestern Medical York, NY Jason A. Miranda Harrisonburg, VA Xavier University of Center at Dallas University of Texas at Austin Daniel A. Wubah Louisiana, New Orleans Kenneth J. Dery Julie L. Tubbs Cheryl L. Stevens Beckman Research Institute Opeyemi Olabisi Kingsborough Community Scripps Research Institute, City of Hope National Yeshiva University, New College, City University of La Jolla, CA MBRS SCORE AWARD Medical Center, Duarte, CA York, NY New York (listed by institution and Wanda H. Vila-Carriles Arthur Zeitlin principal investigator) Luis A. Estrella-Perez Miguel A. Padilla Baylor College of Medicine, University of Medicine and University of Florida, University of Delaware, Houston, TX Hampton University, VA Dentistry of New Jersey Gainesville Newark Hugh M. McLean Robert Wood Johnson Igor Vivanco David C. Usher Medical School, Piscataway Ainsley A. Parkison University of California, Bridges to the Doctorate MARC ANCILLARY TRAINING Herbert H. Lehman College, Los Angeles City University of New York Montclair State University, ACTIVITIES AWARD Jessica H. Fong Upper Montclair, NJ (listed by institution and Princeton University, NJ Bonnie K. Lustigman principal investigator) American Association for the Advancement of Science, Washington, DC ACRONYMS USED IN THIS ISSUE Shirley M. Malcom University of North Carolina ABRCMS Annual Biomedical Research Conference for Minority Students at Chapel Hill CSUDH California State University, Dominguez Hills Walter E. Bollenbacher CUNY City University of New York MARC U*STAR AWARDS GRE Graduate Record Examinations (listed by institution and principal investigator) MARC Minority Access to Research Careers Northern Arizona University, MBRS Minority Biomedical Research Support Flagstaff MORE Minority Opportunities in Research . Fernando P Monroy NIDDK National Institute of Diabetes and Digestive and Kidney Diseases Savannah State University, GA NIGMS National Institute of General Medical Sciences Harpal Singh NIH National Institutes of Health University of Minnesota, PTSD Post-Traumatic Stress Disorder Duluth Benjamin L. Clarke SACNAS Society for Advancement of Chicanos and Native Americans in Science SJSU San Jose State University INSTITUTIONAL RESEARCH AND ACADEMIC CAREER UAPB University of Arkansas at Pine Bluff DEVELOPMENT AWARD UCLA University of California, Los Angeles (listed by institution and principal investigator) UCSD University of California, San Diego UCSF University of California, San Francisco University of Kansas, Lawrence UMBC University of Maryland, Baltimore County C.R. Middaugh UVM University of Vermont National Institute of General Medical Sciences 45 Center Drive MSC 6200 FIRST-CLASS MAIL Bethesda, MD 20892-6200 POSTAGE & FEES PAID DHHS/NIH Ofﬁcial Business Penalty for Private Use, $300 Permit No. G-813 Printed on 50% recycled content paper and can be recycled as white ofﬁce paper.
Pages to are hidden for
"p2 021206GMS minority -cr"Please download to view full document