Thyroid Modality Chemical Propylthiouracil Phenobarbital Thyroxine LSodium perchlorate

							Thyroid Modality
                                                                                Fish
                           Frog                Intact    Male      Female                                                   AR      Hersh-   Utero-
Chemical                             (407)                                     repro   Steroid     Arom      ER binding
                           Thyroid              male    Pubertal   Pubertal                                               binding   berger   trophic
                                                                              screen
Propylthiouracil              X        X         X         X          X
Phenobarbital                                    X         X          X
Thyroxine, L-                 X        X
Sodium perchlorate            X                            X          X         X
Thiram                                                     X          X
PBDE                                                       X          X
Ethylthiouracil               X
Amitrole                      X
Methimizole                   X
Iopanoic acid                 X



Neuroendocrine
                             ER        AR      Hersh-   Utero-                Intact    Male      Female     Fish repro
Chemical                                                            (407)                                                 Steroid   Arom
                           binding   binding   berger   trophic                male    Pubertal   Pubertal     screen
Clomiphene citrate            X
Atrazine                               X                                                  X          X           X                    X
Dexamethasone                          X
Apomorphine                                                                     X
Haloperidol                                                                     X         X
Reserpine                                                                                 X




Steroidogenesis Modality
                             ER        AR      Hersh-   Utero-                Intact    Male      Female     Fish repro
Chemical                                                            (407)                                                 Steroid   Arom
                           binding   binding   berger   trophic                male    Pubertal   Pubertal     screen
Dimethoate                                                                                                                  X
Lindane                                                                                                                     X         X
Aminogluthethimide                                                                                                          X         X
Flutamide                                        X                   X          X         X                      X          X
Genestein                                                  X         X                                                      X         X
Ketoconazole                                                                    X         X          X                      X         X
Bisphenol A                                                                                                                 X
Epostane                                                                                                                    X
Linuron                                                                                   X          X
Spironolactone                         X
Aromatase Modality
                            ER        AR      Hersh-   Utero-            Intact    Male      Female     Fish repro
Chemical                                                         (407)                                               Steroid   Arom
                          binding   binding   berger   trophic            male    Pubertal   Pubertal     screen
Aminoglutethimide                                                                                                      X        X
4-Hyroxyandrostenedione               X                                                                                         X
Chrysin                                                                                                                         X
Genistein                                                                                                              X        X
Econazole                                                                                                                       X
Ketoconazole                                                               X         X          X                      X        X
Fenarimol                                                                                       X
Fadrazole                                                                  X                                X
Prochloraz                                                                           X          X                      X
CGS 18320B                                                        X
Linuron                                                                              X          X
Anastrozole                                                                X