Can Mosquitoes Transmit HIV ? Dr. Sujnanendra Mishra, MD How Mosquitoes spread MALARIA Dr.Sujnanendra Mishra 2 How would HIV get from a mosquito to you? • During a bite, the mosquito injects saliva into your blood. This keeps your blood liquid, and easy for the mosquito to take. • The mosquito sucks, and leaves. Any mosquito saliva left is all that could contain a possible HIV particle. It looks like a mosquito does not transfer much from “meal to meal”. HIV particles would have to somehow get into the saliva of the mosquito, and then be transferred to a new person. Dr.Sujnanendra Mishra 3 Probable situations for transfer: There are THREE hypothetical situations which would allow mosquitoes to transmit HIV. 1.First , a mosquito would initiate the cycle by feeding on an HIV positive carrier and bite a non-infected person , 2. Second , a mosquito after partial feed on an HIV carrier and completes blood meal on a different individual. 3. Third, Squishing a mosquito on a open wound carrying HIV particle . Dr.Sujnanendra Mishra 4 Mosquitoes Digest the Virus that Causes AIDS INFECTING AGENTS SURVIVAL PERIOD inside mosquito Malaria parasites 9-12 days and actually go through a series of necessary life stages during that period. 10-25 days inside a mosquito and replicate enormously during the incubation period. 1-2 days and completely destroy any virus particles that could potentially produce a new infection. Encephalitis virus HIV- Since the virus never survive to reproduce and to invade the salivary glands, the mechanism that most mosquito-borne parasites use to get from one host to the next is not possible with HIV. Dr.Sujnanendra Mishra 5 Mosquitoes Are Not Flying Hypodermic Needles The food canal and salivary canal are separate ways in the mosquito. The mosquito's feeding apparatus is an extremely complicated structure that is totally unlike the crude single-bore syringe. Unlike a syringe, the mosquito delivers salivary fluid through one passage and draws blood up another. Food canal and salivary canal are not the same.. Dr.Sujnanendra Mishra 6 Concurrent bites don't spread HIV The mechanics involved in mosquito feeding are totally unlike the mechanisms employed by the drug user's needles. In short, mosquitoes are not flying hypodermic needles and a mosquito that disgorges saliva into your body is not flushing out the remnants of its last blood meal. Dr.Sujnanendra Mishra 7 Mosquitoes Do Not Ingest Enough HIV Particles to Transmit AIDS HIV circulates at very low levels in the blood--. Infected individuals rarely circulate more that 10 units of HIV, and 70 to 80% of HIV-infected persons have undetectable levels of virus particles in their blood. Crushing a fully engorged mosquito containing AIDS positive blood would still not begin to approach the levels needed to initiate infection. Ingested blood contains suboptimal level of HIV particle. Many of them might have been digested at the time of crushing. Dr.Sujnanendra Mishra 8 When you account for each step, the odds are extremely minimal of getting AIDS from a mosquito. So, you really don't have to worry about getting AIDS from a mosquito bite. If you're still worried, remember that not one case has ever been documented. Dr.Sujnanendra Mishra 9 ENJOY !!!