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2010 NGM Joint Meeting Program
August 27-29, 2010
POSTER SESSION
Friday, August 27, 2010 and Saturday, August 28, 2010
12:00-2:30 pm
Appetite Regulation, Satiety, Obesity, and Nutrition
Poster No.
1 EFFECTS OF KAOLINITE INGESTION ON LIPID ABSORPTION AND WEIGHT
REGULATION. F Angel, C Fischer, F Voinot, A Boeuf, L Sabatier, J Lignot, and N Liewig,
Strasbourg, France. Program 73
2 ROLE OF THE INTESTINAL SEROTONERGIC SYSTEM IN THE DEVELOPMENT OF
HIGH-FAT DIET-INDUCED OBESITY AND INCEPTIVE NON-ALCOHOLIC FATTY
LIVER DISEASE (NAFLD) IN MICE. SC Bischoff, S Haub, A Spruss, G Kanuri, P Enck, S
Zipfel, and Y Ritze, Stuttgart, Germany. University of Hohenheim Program 74
3 A PILOT STUDY EVALUATING THE ROLE OF COMBINED IMPEDANCE-PH
MONITORING IN THE EVALUATION OF ASIAN PATIENTS WITH SUSPECTED
SUPRA-ESOPHAGEAL MANIFESTATIONS OF GERD: ESTABLISHING THE
PRESENCE OF ACID AND NON-ACID REFLUX. D Ang, TL Ang, CH Poh, KM Fock,
Singapore. Changi General Hospital Program 75
4 DIFFERENCES IN GUSTATORY AND GASTROINTESTINAL (GI) SENSITIVITY TO
OLEIC ACID BETWEEN LEAN AND OBESE. C Feinle-Bisset, JE Stewart, RV Seimon, B
Otto, R Keast, and P Clifton, Adelaide, Melbourne, Australia, and Munich, Germany. University of
Adelaide Discipline of Medicine Program 76
5 EFFECTS OF ACUTE ENERGY RESTRICTION ON GASTROINTESTINAL MOTOR,
HORMONE, AND ENERGY INTAKE RESPONSES TO DUODENAL LIPID IN OBESE
MEN. C Feinle-Bisset, IM Brennan, RV Seimon, ND Luscombe-Marsh, B Otto, and M Horowitz,
Adelaide, Australia and Munich, Germany. University of Adelaide Program 77
6 GUT PEPTIDES GIP, GLP-1 AND ENTEROGLUCAGON INCREASE, WHILE GHRELIN
DECREASES TO IMPROVE GLUCOSE HOMEOSTASIS WITH GRADUALLY
INCREASED RETENTION OF ACETAMINOPHEN AFTER GASTRIC BYPASS
SURGERY FOR OBESITY. PM Hellström, Y Falken, E Näslund, and JJ Holst, Uppsala and
Stockholm, Sweden, and Copenhagen, Denmark. Uppsala University Program 78
7 INTRAGASTRIC PRESSURE: A MAJOR DETERMINANT OF SATIATION?
P Janssen and J Tack, Leuven, Belgium. Center for Gastroenterological Research Program 79
8 IMPAIRED GASTRIC ACCOMMODATION DECREASES FOOD INTAKE BY
INCREASING THE INTRAGASTRIC PRESSURE. P Janssen, S Verschueren, and J Tack,
Leuven, Belgium. Center for Gastroenterological Research Program 80
Poster No.
9 THE EFFECT OF CHRONIC ORAL MONOSODIUM GLUTAMATE ADMINISTRATION
UNDER CHRONIC VARIABLE STRESS IN ADULT RAT. Y Kim, S Choi, HS Ryu, HJ Seo,
and MY Lee, Iksan, South Korea. Wonkwang University Program 81
10 THE ROLE OF ENDOGENOUS CHOLECYSTOKININ IN THE REGULATION OF
GASTRIC EMPTYING IN LEAN AND OBESE INDIVIDUALS. E Patel, RB Jones, TJ Little,
MD Amato, JT Mclaughlin, and DG Thompson, London, Manchester, United Kingdom, and
Monza, Italy. University of Manchester Program 82
11 LEPTIN STIMULATES NEURONS IN THE GUINEA-PIG SUBMUCOUS AND
MYENTERIC PLEXUS. F Reichardt, B Kuch, and M Schemann, Freising, Germany. Technische
Universität München Program 83
12 FASTING AND REFEEDING EPISODES ALTER MOTOR PATTERNS AND NNOS-
EXPRESSION IN THE JEJUNUM. LJ Roosen, W Boesmans, M Dondeyne, J Tack, and P
Vanden Berghe, Leuven, Belgium. Center for Gastroenterological Research Program 84
13 CAN WE DISCRIMINATE BETWEEN “MANPUKU” (SATIETY) AND “BOUMAN”
(EPIGASTRIC BLOATING)? Y Sakamoto, M Inamori, H Iida, T Akiyama, T Ikeda, and A
Nakajima, Yokohama and Tokyo, Japan. Yokohama City University Program 85
14 LONG-TERM FOLLOW UP OF PERIPHERAL NERVE STIMULATION OF THE
OCCIPITAL REGION- CERVICAL DERMATOME 1 AND 2- IN MORBIDLY OBESE
SUBJECTS. I Sarosiek, K Roeser, J Grant, and RW McCallum, El Paso, TX and Kansas City, KS.
Texas Tech University Health Sciences Center Program 86
Biliary and Small Intestinal Physiology, Pathophysiology, and Clinical Disorders
15 NEURAL INVASION IN PANCREATIC CANCER IS ASSOCIATED WITH A TARGETED
MIGRATION OF SCHWANN CELLS TO PANCREATIC CANCER CELLS. GO Ceyhan, I
Demir, A Boldis, T Kehl, and H Friess, Munich, Germany. Technische Universität München
Program 87
16 SMALL INTESTINAL MOTILITY IN PATIENTS WITH NEUROENDOCRINE TUMORS
EVALUATED BY MOTILITY TRACKING SYSTEM. T Gregersen, J Worsoe, H Gronbaek, V
Schlageter, S Laurberg, and K Krogh, Aarhus, Denmark and Lausanne, Switzerland. Aarhus
University Hospital Program 88
17 EFFECTS OF MODULATORS OF THE VOLTAGE-GATED CA2+ CHANNELS ON
ENTERIC NEURONS AND MOTILITY OF CONTROL AND INFLAMED INTESTINE.
K Nurgali, JY Choi, M Ellis, B Hunne, and R Bron, Melbourne, Victoria, AC, Parkville, VIC,
Australia. The University of Melbourne Program 89
18 CELIAC DISEASE IN PATIENTS WITH A HISTORY OF IRRITABLE BOWEL
SYNDROME. KM Robson and DL Burns, Burlington, MA. Lahey Clinic Medical Center
Program 90
19 INFLUENCE OF SMALL INTESTINAL BACTERIAL OVERGROWTH ON MOTILITY
INDEX PARAMETERS AND TRANSIT TIME RECORDED BY WIRELESS MOTILITY
CAPSULE TECHNOLOGY. I Sarosiek, B Sochacka, K Roeser, J Sarosiek, and RW McCallum,
El Paso, TX and Kansas City, KS. Texas Tech University Health Sciences Center Program 91
Poster No.
20 A NOVEL MURINE MODEL FOR THE STUDY OF EDEMA-INDUCED INTESTINAL
CONTRACTILE DYSFUNCTION. SK Shah, SD Moore-Olufemi, KS Uray, F Jimenez, PA
Walker, H Xue, RH Stewart, GA Laine, and CS Cox, Houston, TX and College Station, TX.
University of Texas Medical School at Houston Program 92
21 THE OCCURRENCE OF SMALL INTESTINAL BACTERIAL OVERGROWTH IN
PRIMARY BILIARY CIRRHOSIS. S Sidani, C Vincent, and M Bouin, Montreal, Quebec,
Canada Universite de Montreal Program 93
22 PAK-MEDIATED REGULATION OF MYPT1 PHOSPHORYLATION IN EDEMATOUS
INTESTINAL SMOOTH MUSCLE. KS Uray, SK Shah, and CS Cox, Houston, TX. University
of Texas Medical School at Houston Program 94
23 THE MULTI-HERBAL DRUG STW 5 (IBEROGAST): POTENTIAL MECHANISMS FOR
THE TREATMENT OF IRRITABLE BOWEL SYNDROME. U Voss, S Michael, S Hoser, O
Kelber, D Weiser, and K Nieber, Leipzig and Darmstadt, Germany. University of Leipzig
Program 95
24 SMOOTH MUSCLE FUNCTION OF PARTIAL OBSTRUCTED INTESTINAL SEGMENT
OF GUINEA PIGS IN VITRO - EVALUATION OF PHASIC AND TONIC STRESS-
STRAIN CURVES. J Zhao, D Liao, J Yang, and H Gregersen, Aalborg, Denmark and La Jolla,
California. Mech-Sense, Aalborg Hospital Science and Innovation Center Program 96
25 STRESS AND STRAIN ANALYSIS OF CONTRACTIONS DURING RAMP DISTENSION
IN PARTIALLY OBSTRUCTED GUINEA PIG JEJUNUM. J Zhao, D Liao, J Yang, and H
Gregersen, Aalborg, Demark and La Jolla, California. Mech-Sense, Aalborg Hospital Science and
Innovation Center Program 97
Brain Gut Axis: Animal Studies
26 SEQUELAE OF CHEMOTHERAPY: EFFECT OF CHRONIC CISPLATIN ON
INTESTINAL MOTOR FUNCTION AND ASSOCIATED HISTOLOGICAL AND
MOLECULAR ALTERATIONS IN THE RAT. R Abalo, G Vera, MA Castillo, C Garc-A-
Jimenez, Jm Garc-A-Mart-Nez, R De Giorgio, and MI Mart-N, Alcorcon, and Bologna, Italy. Rey
Juan Carlos Program 98
27 RESPONSES OF BRAINSTEM VAGAL NEUROCIRCUITS TO OXYTOCIN ARE
UNCOVERED IN A RODENT MODEL OF FUNCTIONAL DYSPEPSIA. T Babic, KN
Browning, and R Travagli, Hershey, PA. Pennsylvania State University Program 99
28 SPINAL CORD INJURY DECREASES RESPONSE OF BRAINSTEM VAGAL NEURONS
TO GHRELIN. KN Browning, R Travagli, and GM Holmes, Hershey, PA and Baton Rouge, LA.
Pennsylvania State University Program 100
29 SEQUELAE OF CHEMOTHERAPY: EFFECT OF CHRONIC CISPLATIN ON VISCERAL
SENSITIVITY IN THE RAT. MA Castillo, R Abalo, V López-Miranda, G Vera, PA Cabezos, and
MI Martín, Alcorcón, Madrid, Spain. Universidad Rey Juan Carlos Program 101
30 DETECTION OF CORTICOTROPIN-RELEASING FACTOR (CRF) IN THE PLASMA BY
THE RAPID METHOD AND REGULATION BY ENDOTOXIN IN RATS. M Goebel, A
Stengel, L Wang, JR Reeve, and Jr., Y Taché, Los Angeles, CA. David Geffen School of Medicine
at UCLA Program 102
Poster No.
31 CRF2 RECEPTOR ACTIVATION BLUNTS STRESS AND CRF-INDUCED COLONIC
MOTOR FUNCTION IN RODENTS. G Gourcerol, V Wu, P Yuan, M Miapamba, M Larauche,
T Amano, P Sanders, J Rivier, Y Taché, and M Mulugeta, Los Angeles and San Diego, CA. David
Geffen School of Medicine at UCLA Program 103
32 CHRONIC STRESS IS ASSOCIATED WITH REGION-SPECIFIC CHANGES IN
ENDOCANNABINOID (CB1) AND ENDOVANILLOID (TRPV1) RECEPTORS IN DRG
NEURONS INNERVATING THE RAT COLON. S Hong, G Zheng, and JW Wiley, Ann Arbor,
MI. University of Michigan Program 104
33 MAST CELLS ARE EARLY RESPONDERS DRIVING MESENTERIC AFFERENT SIGNALING
DURING INTESTINAL ISCHEMIA. W Jiang and D Grundy, Sheffield, United Kingdom. The
University of Sheffield Program 105
34 REPEATED PSYCHOLOGICAL STRESS INDUCES AN OPIATE INDEPENDENT
IMMEDIATE VISCERAL ANALGESIA BUT NO SUSTAINED HYPERALGESIA AS
ASSESSED BY A NEW NON-INVASIVE MANOMETRY METHOD. M Larauche, A Mulak,
Y Kim, M Million, And Y Taché, Los Angeles, CA. David Geffen School of Medicine at UCLA
Program 106
35 CENTRAL GLP-1 RECEPTORS ARE INVOLVED IN THE EMETIC REFLEX OF
SUNCUS MURINUS (HOUSE MUSK SHREW). JA Rudd, SW Chan, G Lin, and DTW Yew,
China. Chinese University of Hong Kong Program 107
36 MELANIN CONCENTRATING HORMONE-IMMUNONEUTRALIZATION INHIBITS
COLITIS-ASSOCIATED INTESTINAL FIBROSIS. DC Ziogas, Y Wang, S Mustafa, Y Tseng,
L McDougal, Y Popov, D Schuppan, and E Kokkotou, Boston, MA. Harvard Medical School
Program 108
Colon and Anorectum: Physiology, Pathophysiology, and Clinical Disorders
37 IRRITABLE BOWEL SYNDROME SUBTYPING BY BRISTOL STOOL FORMS IN
BANGLADESHI PATIENTS. MM Ahmad, Dhaka, Bangladesh. LabAid Medical College
Hospital Program 109
38 A NOVEL METHOD OF MEASURING ANORECTAL FUNCTION USING
DISTENSIBILITY TESTING. MM Alqudah, A Brokjaer, G H, and BP McMahon, Dublin, Ireland
and Aalborg, Denmark. Institute of Technology Tallaght Program 110
39 ROLE OF 7 NICOTINIC ACETYLCHOLINE RECEPTOR SUBTYPES IN DEXTRAN
SULFATE SODIUM-INDUCED COLITIS MODEL IN MICE.
SD AlSharari, I Damaj, and H Akbarali, Richmond, VA. Virginia Commonwealth University
Program 111
40 DO MYOGENIC MECHANISMS EXPLAIN INCREASED RECTAL STIFFNESS IN
FECAL INCONTINENCE (FI)? AE Bharucha, BM Seide, J Edge, and AR Zinsmeister,
Rochester, MN. Mayo Clinic Program 112
41 DISRUPTED COLONIC MOTILTY IN LEP ob/ob TYPE II DIABETIC MICE.
PJ Blair, S Hwang, Y Bayguinov, KM Sanders, and SM Ward, Reno, NV. University of Nevada
Program 113
Poster No.
42 THE CYTOKINESIS BLOCKED MICRONUCLEUS (CBMN) ASSAY IS ASSOCIATED
WITH LATE GI SEQUELAE WHICH IMPAIR QUALITY OF LIFE (QOL) OF PATIENTS
3 YEARS AFTER RADIATION THERAPY (RT) FOR CARCINOMA OF THE PROSTATE
(CaP), WHILE DIETARY MICRONUTRIENTS MAY REDUCE THE IMPACT.
R Botten, E Yeoh, AC Di Matteo, J Butters, VS Dhillon, C Salisbury, RH Holloway, and M Fenech,
Adelaide, S Australia. Royal Adelaide Hospital Program 114
43 DIETARY CAROTENOID INTAKE INDEPENDENTLY PREDICTS FOR ACUTE
GASTROINTESTINAL (GI) SEQUELAE FOLLOWING RADIATION THERAPY (RT)
FOR CARCINOMA OF THE PROSTATE (CaP). R Botten, E Yeoh, AC Di Matteo, J Butters,
VS Dhillon, C Salisbury, B Benassi-Evans, RH Holloway, and M Fenech, Adelaide, S Australia.
Royal Adelaide Hospital Program 115
44 RECTAL POWER: A NEW QUANTIFICATION OF RECTAL FUNCTION FROM
CONCURRENT FLUOROSCOPY AND MANOMETRY. JG Brasseur, S Kim, D Hartman, H
Hal, K Ahn, and A Ouyang, University Park and Hershey, PA. Pennsylvania State University
Program 116
45 TOPOGRAPHIC AND MULTIDIMENSIONAL ANAL PRESSURE PROFILES IN
HEALTH, CONSTIPATION, & INCONTINENCE. G Cheeney, A Attaluri, M Nguyen, J
Valestin, C Phillips, and S Rao, Iowa City, IA. University of Iowa Program 117
46 A PIPELINE FOR THE ANALYSIS AND VISUALIZATION OF HIGH-RESOLUTION
COLONIC MANOMETRY RECORDINGS. JB Davidson, L Wiklendt, G O'Grady, JW
Arkwright, AJ Pullan, and PG Dinning, Auckland, New Zealand and Sydney, Australia. University
of Auckland Program 118
47 TISSUE REMODELLING AND DISMOTILITY IN STRIPS FROM COLONIC
DIVERTICULAR DISEASE PATIENTS. F Espin, V Gil, C Admella, M Jiménez, P Clavé and D
Gallego, Barcelona, Spain. Hospital de Mataró Program 119
48 MORPHOLOGICAL CHANGES OF ENTERIC NEURONS IN RATS WITH IBS AND ITS
POTENTIAL ROLE ON INTESTINAL SECRETION. X Fang, S Li, G Fei, X Yang, Z Wang,
and X Sun, Beijing, China. Peking Union Medical College Program 120
49 FUNCTIONAL RESULTS OF SACRAL NERVE STIMULATION FOR IRRITABLE
BOWEL SYNDROME. JL Fassov, L Lundby, K Krogh, S Buntzen, and S Laurberg, Aarhus,
Denmark. Aarhus University Program 121
50 RELATIONSHIP BETWEEN PLATELET-DERIVED GROWTH FACTOR RECEPTOR
(PDGFR POSITIVE CELLS AND ENTERIC NEURONS IN MICE COLON.
M Kurahashi, SD Koh, SM Ward, and KM Sanders, Reno, NV. University of Nevada Reno
Program 122
51 DO PATIENTS WITH DELAYED TRANSIT CONSTIPATION HAVE A HIGHER
PREVALENCE OF DELAYED UPPER GUT TRANSIT? JD Long, S Culler, L Griffin, K
Koch, and NK Thorne, Winston Salem, NC. Wake Forest University Health Sciences
Program 123
Poster No.
52 ALTERATIONS IN NITRERGIC NEUROMUSCULAR TRANSMISSION OF COLONIC
CIRCULAR AND LONGITUDINAL MUSCLE FROM PATIENTS WITH CROHN’S
DISEASE: EFFECT OF CR3294, NEW ANTI-INFLAMMATORY COMPOUND.
MM Maselli, PP Trisolini, FF Pezzolla, II Demma, MM Caruso, OO Letari, and GG Caselli,
Castellana Grotte, Bari and Monza, Italy . Scientific Institute of Gastroenterology Program 124
53 CO-EXISTENCE OF CONSTIPATION AND FAECAL INCONTINENCE: A GREATLY
UNDERAPPRECIATED CLINICAL PROBLEM. SD Mohammed, N Zarate, PJ Lunniss, and S
Scott, London, United Kingdom. Queen Mary, University of London Program 125
54 HOW USEFUL IS WIRELESS MOTILITY CAPSULE IN DIAGNOSIS OF
GASTROINTESTINAL DYSMOTILITY? K Mysore, A Attaluri, J Valestin, and S Rao, Iowa
City, IA. University of Iowa Program 126
55 THE GASTROINTESTINAL FUNCTION AND BIOFEEDBACK THERAPY RESPONSE
IN CONSTIPATED PATIENTS AFTER RADICAL HYSTERECTOMY AND DELIVERY.
SJ Myung, K Lee, N Kim, D Yang, S Yoon, K Kim, B Ye, J Byeon, S Yang, H Jung, and J Kim,
Seoul, Suwon, and Seongnam, Korea. University of Ulsan College of Medicine Program 127
56 NEURAL REGULATION OF THE RAT INTERNAL ANAL SPHINCTER,
HYPERPOLARIZATION AND RELAXATION INVOLVING TWO COMPLEMENTARY
NEUROTRANSMITTERS: NO AND ATP. A Opazo, B Lecea, V Gil, M Jimenez, P Clave, and
D Gallego, Barcelona, Spain. Hospital de Mataró Program 128
57 HIGH RESOLUTION ANORECTAL MANOMETRY AND ULTRASONOGRAPHY OF
INTERNAL ANAL SPHINCTER IN PATIENTS WITH ANAL FISSURE. A Opazo, E
Aguirre, and P Clave, Barcelona, Spain. Hospital de Mataró Program 129
58 CLINICALLY RELEVANT CORRELATIONS THAT DESCRIBE THE PROCESS OF
DEFECATION. A Ouyang, S Kim, D Hartman, H Hal, K Ahn, and J Brasseur, University Park and
Hershey, PA. Pennsylvania State University Program 130
59 FATIGABILITY OF THE EXTERNAL ANAL SPHINCTER IN INFLAMMATORY
BOWEL DISEASE: SIGNIFICANCE IN FECAL URGENCY AND INCONTINENCE.
AA Papathanasopoulos, KH Katsanos, DK Christodoulou, A Tatsioni, and EV Tsianos, Ioannina,
Greece. University of Ioannina Medical School Program 131
60 THE ATYPICAL CANNABINOID O-1602 PROTECTS AGAINST DSS- AND TNBS-
INDUCED COLITIS IN MICE. R Schicho, M Bashashati, D Saur, A Zimmer, KA Sharkey, and
M Storr, Calgary, AB, Canada, Munich and Bonn, Germany. University of Calgary Program 132
61 IS COLONIC MANOMETRY USEFUL IN EVALUATION OF SENSORIMOTOR
DYSFUNCTION IN SLOW TRANSIT CONSTIPATION (STC)? S Singh, D Dickinson, and S
Rao, Iowa City, IA. University of Iowa Program 133
62 HIGH RESOLUTION ANORECTAL MANOMETRY-COMPARISON WITH WATER
PERFUSION MANOMETRY AND DEFECOGRAPHY. C Sohn, J Park, D Park, Y Cho, H
Kim, W Jeon, B Kim, P Rhee, M Park, and J Kwon, Seoul, Busan and Daegu, Korea.
Sungkyunkwan University Program 134
63 COMBINED STUDY USING ANORECTAL MANOMETRY AND ENDOSCOPIC
ULTRASOUND TO ESTABLISH A MANOMETRIC CUT OFF TO IDENTIFY
SPHINCTER THICKNESS AND SURGICALLY CORRECTABLE SPHINCTER
Poster No.
DEFECTS. NK Thorne, S Sastry, S Kundu, J Conway, and G Mishra, Winston Salem, NC. Wake
Forest University Health Sciences Program 135
64 NON-NEURONAL RELEASE OF ACETYLCHOLINE PLAYS A KEY ROLE IN
SECRETORY RESPONSE TO LUMINAL PROPIONATE IN RAT COLON. T Yajima, M
Matsumoto, M Yajima, and R Inoue, Sapporo, Kyoto and Shizuoka, Japan. Hokkaido University
Program 136
Electrical Control of the GI Tract
65 THE ELECTROPHYSIOLOGICAL BASIS OF THE EGG EXPLAINED VIA MAPPING
AND VIRTUAL MODELING. P Du, G O'Grady, R Komuro, AJ Pullan, and LK Cheng,
Auckland, New Zealand. The University of Auckland Program 137
66 MUCOSAL ELECTROPHYSIOLOGICAL CHANGES IN PATIENTS WITH
GASTROPARESIS AFTER TEMPORARY GASTRIC ELECTRICAL STIMULATION.
BF Heindl, D Spree, A Kedar, C Lahr, SDF To, and TL Abell, Jackson, MS. University of
Mississippi Medical Center Program 138
Enteric Neurons: Development and Degeneration
67 GDNF mRNA EXPRESSION IS ALTERED IN PATIENTS WITH DIVERTICULAR
DISEASE - UNDERLYING MECHANISMS AND FUNCTIONAL IMPLICATIONS.
M Böttner, D Zorenkov, HP Bruch, UJ Roblick, JH Egberts, KH Schäfer, and T Wedel, Kiel and
Kaiserslautern, Germany. University of Kiel Program 139
68 DIFFERENTIAL EFFECT OF HYPERTHERMIA ON NERVES AND SMOOTH MUSCLE
OF THE MOUSE ILEUM. S Burke, B Abu-Wasel, A Nissan, A Eid, and M Hanani, Jerusalem,
Israel. Hadassah University Program 140
69 PRENATAL DEVELOPMENT OF THE MYENTERIC PLEXUS IN THE HUMAN
SIGMOID COLON. S Singh and A Shariff, New Delhi, India. All India Institute of Medical
Sciences Program 141
Esophageal Physiology, Pathophysiology, and Clinical Disorders
70 ENDOSCOPICALLY ASSISTED WATER PERFUSION ESOPHAGEAL MANOMETRY
WITH MINIMAL SEDATION TECHNIQUE. R Brun, K Staller, S Viner, and B Kuo, Boston,
MA. Harvard Medical School Program 142
71 HIGH RESOLUTION MANOMETRY CRITIERIA PREDICTING INCOMPLETE BOLUS
CLEARANCE. YK Cho, MG Choi, YJ Jeon, HS Chung, JE Lee, WC Kim, SH Cho, CH Lim, JS
Kim, JM Park, IS Lee, SW Kim, GY Choi, and IS Chung, Seoul, Korea. Catholic University
Program 143
72 EVALUATION OF GASTROESOPHAGEAL REFLUX WITH THE 24 HR
MULTICHANNEL INTRALUMINAL IMPEDANCE-pH PROBE IN CHILDREN WITH
RECURRENT LARYNGITIS. J Cohen Sabban, G Donato Bertoldi, L Olleta, J Razzetti, and M
Orsi, Buenos Aires, Argentina. Italian Hospital Program 144
Poster No.
73 INFLUENCE OF BOLUS VISCOSITY AND POSITION ON ESOPHAGEAL
CONTRACTION AND TRANSIT. J Dalmazo, LO Aprile, and RO Dantas, Ribeirão Preto, SP,
Brazil. University of Sao Paulo Program 145
74 SCINTIGRAPHIC EVALUATION OF SALIVA TRANSPORT TO THE DISTAL
ESOPHAGUS IN PATIENTS WITH GASTROESOPHAGEAL REFLUX DISEASE.
RO Dantas and RA Cassiani, Ribeirão Preto, SP, Brazil. University of Sao Paulo Program 146
75 A COMPARISON OF ACID AND NON-ACID REFLUX IN THE EVALUATION OF
PATIENTS WITH TYPICAL VERSUS ATYPICAL MANIFESTATIONS OF
GASTROESOPHAGEAL REFLUX DISEASE: RESULTS FROM AN ASIAN COHORT.
D Ang, TL Ang, CH Poh, KM Fock, Singapore. Changi General Hospital. Program 147
76 PHENOTYPING PAIN IN HEALTH - PSYCHOPHYSIOLOGICAL RESPONSES TO
PAIN. AD Farmer, SJ Coen, H Naqvi, and Q Aziz, London, United Kingdom. Queen Mary,
University of London Program 148
77 OESOPHAGEAL PERFUSION OF LOW CONCENTRATIONS OF DEOXYCHOLIC ACID
IMPAIRS MUCOSA INTEGRITY IN RABBITS. R Farré, M Vicario, N Perdon, H Vanheel, K
Blondeau, M Jimenez, D Sifrim, and J Tack, Leuven, Belgium, Barcelona, Spain, and London,
United Kingdom. Center for Gastroenterological Research Program 149
78 THE ESOPHAGEAL MOTILITY RESPONSE TO PHYSIOLOGIC CHALLENGE IN
HEALTH, NON-EROSIVE AND EROSIVE GASTRO-ESOPHAGEAL REFLUX DISEASE.
MR Fox, CF Daum, R Sweis, E Kaufman, A Fuelleman, A Anggiansah, and M Fried, Nottingham,
United Kingdom, Zürich, Switzerland, and London, United Kingdom. University of Nottingham
Program 150
79 DISEASE-SPECIFIC HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH
SYMPTOMATIC ESOPHAGEAL ACHALASIA INCREASES AFTER THERAPY IN
ASSOCIATION WITH SYMPTOM IMPROVEMENT. V Garrigues, V Ortiz, C Casanova, L
Bujanda, E Moreno-Osset, M Rodríguez-Téllez, A Montserrat, Á Brotons, E Fort, and J Ponce,
Spain. Hospital La Fe, Valencia Program 151
80 RESPIRATORY SYMPTOMS DURING GASTRO-ESOPHAGEAL REFLUX ARE
ASSOCIATED WITH INCREASED EXHALED 8-ISOPROSTANE LEVELS: RESULTS OF
A PILOT STUDY. G Gourcerol, C Elie, E Verin, P Ducrotté, F Ziegler, and AM Leroi, Rouen,
France. Rouen University Hospital Program 152
81 DIAGNOSTIC CONTRIBUTION OF 24H IMPEDANCE COMPARED TO 24H
OESOPHAGEAL PH MONITORING: STUDY ON 220 CONSECUTIVE PH-IMPEDANCE
IN A TERTIARY CENTER. G Gourcerol, B Salem, E Verin, E Houivet, A Leroi, and P Ducrott
T, Rouen, France. Rouen University Hospital Program 153
82 A PILOT STUDY ON THE RELATION BETWEEN GERD AND LPRD BASED ON
SYMPTOMS. F Guijian, Z LiLI, and L Yulan, Beijing, China. Peking University, People's
Hospital Program 154
83 PATHOPHYSIOLOGICAL FINDINGS IN PATIENTS WITH NONCARDIAC CHEST
PAIN. J Gunnarsson, J Brun, AM Drewes, H Gregersen, and M Simren, Gothenburg, Sweden and
Aalborg, Denmark. University of Gothenburgh Program 155
Poster No.
84 EFFECT OF GESTATIONAL AND POST NATAL MATURATION ON RESPONSE
SENSITIVITY AND DURATION OF ESOPHAGO-UPPER ESOPHAGEAL SPHINCTER
CONTRACTILE REFLEX (UESCR) AND LOWER ESOPHAGEAL RELAXATION
RESPONSE (LESRR) IN HUMAN NEONATES. SR Jadcherla, J Peng, V Parks, R Moore, and
S Fernandez, Columbus, OH. The Ohio State University Program 156
85 VALIDATION OF THE ASAN MAYO DYSPHAGIA QUESTIONNAIRE-30 IN PATIENTS
WITH ACHALASIA AS JUDGED BY HIGH-RESOLUTION MANOMETRY. K Jung, H
Jung, I Yoon, D Kim, K Choi, K Choi, H Song, G Lee, and J Kim, Seoul, Korea. University of
Ulsan, College of Medicine Program 157
86 THE MANOMETRIC CHARACTERISTICS OF OPIOID ESOPHAGEAL DYSMOTILITY
DISORDER BY HIGH-RESOLUTION IMPEDANCE MANOMETRY. K Jung, RE Kraichely,
AS Arora, and JA Murray, Seoul, Korea and Rochester, MN. Mayo Clinic Program 158
87 DECREASED SENSITIVITY IN PATIENTS WITH BARRETT’S ESOPHAGUS BOTH IN
THE METAPLASTIC AND THE NORMAL PART OF ESOPHAGUS. AL Krarup, SS Olesen,
P Funch-Jensen, H Gregersen, and AM Drewes, Aalborg and Aarhus, Denmark. Aarhus University
Program 159
88 EFFECTS OF CHILI ON GASTRIC ACCOMMODATION AND GASTROINTESTINAL
SYMPTOMS IN GERD AND HEALTHY VOLUNTEERS. C Kriengkirakul, P Vasavid, and S
Gonlachanvit, Bangkok, Thailand. Chulalongkorn University Program 160
89 ESOPHAGEAL MOTOR FUNCTION AND BOLUS TRANSIT ON HIGH-RESOLUTION
IMPEDANCE MANOMETRY (HRM) IN NORMAL SUBJECTS. N Kumar and C Gyawali, St.
Louis, MO. Washington University School of Medicine Program 161
90 ISOLATING THE CONTRACTILE ELEMENTS OF THE ESOPHAGOGASTRIC
JUNCTION (EGJ) USING A NOVEL 3-D HIGH RESOLUTION MANOMETRY PROBE (3-
D HRM). MA Kwiatek, S Roman, JE Pandolfino, T Nealis, and PJ Kahrilas, Chicago, IL.
Northwestern University Program 162
91 DISTAL ESOPHAGEAL EMPTYING: A MECHANISTIC ANALYSIS USING 3D HIGH-
RESOLUTION / CIRCUMFERENTIAL HIGH-RESOLUTION MANOMETRY (3D-
HRM/CHRM) COUPLED WITH VIDEOFLUOROSCOPY AND A SQUAMOCOLUMNAR
JUNCTION ENDOCLIP. MA Kwiatek, S Roman, JE Pandolfino, T Nealis, and PJ Kahrilas,
Chicago, IL. Northwestern University Program 163
92 RELATIONSHIP BETWEEN SYMPTOMATIC GASTROESOPHAGEAL REFLUX,
SLEEP PARAMETERS, DAYTIME SLEEPINESS AND SLEEP QUALITY IN PATIENTS
WITH OBSTRUCTIVE SLEEP APNEA. J Kwon, C Sohn, P Rhee, S Choi, and K Park, Daegu,
Iksan and Seoul, Korea. Catholic University of Daegu Program 164
93 CLINICAL PHARMACOKINETICS AND PHARMACODYNAMICS OF ARBACLOFEN
PLACARBIL, A NOVEL REFLUX INHIBITOR, IN SUBJECTS WITH GERD. R Lal, K
Zomorodi, FJ Huff, W Luo, J Tovera, R Blumenthal, A Bian, and KC Cundy, Santa Clara, CA.
XenoPort, Inc. Program 165
94 PROTEOMIC EVIDENCE SUGGESTIVE OF IMMUNE-MEDIATED NEURONAL
DESTRUCTION OR NEURODEGENERATION IN PATIENTS WITH ACHALASIA.
K Lee, M Yeo, S Meung, N Kim, and S Cho, Suwon, Seoul, and Seongnam, Korea. Ajou University
School of Medicine Program 166
Poster No.
95 THE REFLUX PATTERN OF GERD PATIENTS WITH GLOBUS IS CHARACTERIZED
BY A NONACID REFLUX. J Lee, T Lee, H Im, Y Jung, S Hong, H Park, Y Kang, and K Hur,
Seoul and Daejon, Korea. Soonchunhyang University Program 167
96 BODY POSITION AND BREATHING PATTERN CAN AFFECT THE RESULTS OF HIGH
RESOLUTION MANOMETRY IN HEALTHY ADULTS. T Lee, J Lee, H Im, Y Jung, J Kim, J
Cho, H Park, Y Kang, and K Huh, Seoul and Daejon, Korea. Soonchunhyang University
Program 168
97 NISSEN FUNDOPLICATION REDUCES THE FREQUENCY OF CLASSIC TWO-PHASE
AND RE-REFLUX ACID GASTROESOPHAGEAL REFLUX EPISODES IN PATIENTS
WITH CYSTIC FIBROSIS. H Mousa and FW Woodley, Columbus, OH. The Ohio State
University Program 169
98 OBESITY SURGERY CONSEQUENCES AFTER GASTRIC SLEEVE, IS THE
ESOPHAGUS SUFFERING? RESULTS OF A COHORT COMPARATIVE MANOMETRIC
STUDY. A Orozco-Gamiz, Guadalajara, Mexico. Gastrolab Clinical Research Program 170
99 NIGHTTIME HEARTBURN: DOES IT REFLECT NIGHTTIME REFLUX? WC Orr and S
Goodrich, Oklahoma City, OK. Lynn Health Science Institute Program 171
100 CLINICAL APPLICATIONS OF THE CHICAGO CLASSIFICATION OF DISTAL
ESOPHAGEAL MOTILITY DISORDERS IN KOREAN PATIENTS. M Park, W Moon, S
Park, K Kim, and S Choi, Busan and Iksan, South Korea. Kosin University College of Medicine
Program 172
101 COMPARISON OF EFFICACY OF TIMED BARIUM ESOPHAGOGRAM WITH THE
ESOPHAGEAL TRANSIT SCINTIGRAPHY ON PATIENTS WITH ACHALASIA. H Park,
K Huh, J Lee, and Y Kang, Seoul and Daejon, Korea. Gangnam Severance Hospital, Yonsei
University Program 173
102 ROLE OF SWALLOW INDUCED GASTROESOPHAGEAL REFLUXES IN NON-
EROSIVE GASTROESOPHAGEAL REFLUX DISEASE (NERD) EVALUATED BY 24 HR
ESOPHAGEAL IMPEDANCE PH TESTING. T Patcharatrakul and S Gonlachanvit, Bangkok, ,
Thailand. Chulalongkorn University Program 174
103 HIGH RESOLUTION MANOMETRY (HRM) IMPROVES TRANSIENT LOWER
ESOPHAGEAL SPHINCTER RELAXATIONS (TLESRS) DETECTION IN HEALTHY
VOLUNTEERS. S Roman, F Zerbib, K Belhocine, S Bruley des Varannes, and F Mion, Chicago,
IL and Nantes, France. Northwestern University Program 175
104 UPPER ESOPHAGEAL SPHINCTER (UES) PRESSURE VARIATIONS DURING
TRANSIENT LOWER ESOPHAGEAL SPHINCTER RELAXATION (TLESR): A
DETERMINANT ROLE OF COMMON CAVITY? S Roman, F Zerbib, K Belhocine, S Bruley
des Varannes, and F Mion, Chicago, IL and Nantes, France. Northwestern University
Program 176
105 DEFINING NON-ACHALASIA SPASTIC DISORDERS IN HIGH RESOLUTION
ESOPHAGEAL PRESSURE TOPOGRAPHY (EPT): TIME TO ABANDON RAPID
PROPAGATION? S Roman, D Luger, MA Kwiatek, JE Pandolfino, and PJ Kahrilas, Chicago, IL.
Northwestern University Program 177
Poster No.
106 AFQ056, AN ALLOSTERIC MODULATOR OF METABOTROPIC GLUTAMATE
RECEPTOR 5, INHIBITS GASTRO-ESOPHAGEAL REFLUX IN ANIMALS AND GERD
PATIENTS. A Rühl, M Rouzade-Dominguez, A Fox, S Bruley des Varannes, J Tack, P
Malfertheiner, R Tutuian, and H Allescher, Basel, Switzerland. Novartis Program 178
107 GASTROESOPHAGEAL MOTILITY PATTERNS IN PATIENTS WITH
REGURGITATION. CP Sanmiguel, M Arabyan, C Chang, JL Conklin, and EE Soffer, Los
Angeles, CA. Cedars Sinai Medical Center Program 179
®
108 PATIENTS REQUEST ’S SCORE IS POSITIVELY ASSOCIATED WITH SEVERITY OF
EXTRAESOPHAGEAL SYMPTOMS IN PATIENTS WITH GORD. A REPORT FROM
THE MEXICAN GORD WORKING GROUP. JC Soto-Perez, Sobrino-Cossio, J Vargas, J
Lopez-Alvarenga, Y Crespo, A Jimenez, A Saez, M Morales-Arambula, and G Mateos, Naucalpan
and Guadalajara, Mexico. Program 180
109 ENDOSCOPICALLY ASSISTED WATER PERFUSION MANOMETRY WITH MINIMAL
SEDATION: INDICATIONS AND IMPLICATION ON THE CLINICAL MANAGEMENT.
K Staller, R Brun, S Viner, and B Kuo, Boston, MA. Harvard Medical School Program 181
110 ROLE OF ADIPONECTIN ON REFLUX ESOPHAGITIS. C Tae, H Jung, S Roh, J Choi, S
Kim, K Shim, T Kim, S Jung, S Yi, K Yoo, and I Moon, Seoul, Korea. Ewha Woman’s University
School of Medicine Program 182
111 ARBACLOFEN PLACARBIL MONOTHERAPY REDUCES GERD SYMPTOMS IN
SUBJECTS WITH A PRIOR RESPONSE TO PPI THERAPY. N Vakil, FJ Huff, A Bian, DS
Jones, and D Stamler, Milwaukee, WI and Santa Clara, CA. University of Wisconsin School of
Medicine and Public Health Program 183
112 LONGITUDINAL SHORTENING OF THE MUCOSA AND CIRCULAR SMOOTH
MUSCLE IN THE DISTAL ESOPHAGUS ON ENDOSCOPIC ULTRASOUND. AK Vegesna,
SP Prabhu, YS Elayampalayam, A Sharma, MI Tiwana, A Jha, JG Brassuer, and LS Miller, Bala
Cynwyd and Philadelphia, PA. Temple University Program 184
Extrinsic Neural Pathways: Afferents and Efferents
113 VAGUS NERVE STIMULATION (VNS): A NEW TOOL FOR THE TREATMENT OF
COLITIS? B Bonaz, D Clarençon, C Picq, J Meregnani, V Sinniger, S Reyt, and O David,
Grenoble, France. Grenoble Institute of Neurosciences Program 185
114 DIFFERENTIAL REGULATION OF TRP CHANNEL FUNCTION IN ACUTE AND
CHRONIC MECHANICAL HYPERSENSITIVITY. SM Brierley, J Castro, CM Martin, AM
Harrington, PA Hughes, and L Blackshaw, Adelaide, Australia. Royal Adelaide Hospital
Program 186
115 ABSENCE OF THE VAGUS NERVE IN THE STOMACH OF TBX1 MUTANT MICE.
AJ Burns, A Calmont, N Thapar, and PJ Scambler, London, United Kingdom. UCL Institute of
Child Health Program 187
116 IMPAIRED DESCENDING INHIBITORY PAIN MECHANISMS IN PATIENTS WITH
CHRONIC PANCREATITIS. JB Frokjaer, SS Olesen, C Brock, AL Krarup, P Funch-Jensen, OH
Wilder-Smith, and AM Drewes, Aalborg, Denmark and Nijmegen, The Netherlands. Aarhus
University Hospital Program 188
Poster No.
117 EEG CLASSIFICATION IN TYPE-1 DIABETES TO IDENTIFY BIOMARKERS FOR
VISCERAL PAIN PROCESSING. JB Frokjaer, C Graversen, D Farina, and AM Drewes,
Aalborg, Denmark and Nijmegen, The Netherlands. Aalborg Hospital Program 189
118 TRPV1 MEDIATES ACID ACTIVATION OF ESOPHAGEAL SENSORY PATHWAYS.
AM Harrington, R Young, SM Brierley, and L Blackshaw, Adelaide, Australia. Royal Adelaide
Hospital and University of Adelaide Program 190
119 MECHANOSENSITIVE RECEPTIVE FIELDS OF SPINAL NOCICEPTIVE AFFERENT
NERVE FIBERS IN THE ESOPHAGUS. M Kollarik, J Halicka, and F Ru, Baltimore, MD and
Martin, Slovakia. The Johns Hopkins University School of Medicine Program 191
120 MECHANO-SENSORY PROPERTIES IN GOTO-KAKIZAKI RAT INTESTINE: A
GENETIC MODEL FOR TYPE 2 DIABETES. J Yang, J Zhao, P Chen, T Nakaguchi, D
Grundy, and H Gregersen, Aalborg, Denmark , Chiba, Japan, and Sheffield, United Kingdom.
Mech-Sense, Aalborg Hospital Program 192
121 MECHANO-SENSORY PROPERTIES OF HYPERTROPHIC INTESTINE FOLLOWING
CHRONIC OBSTRUCTION. J Yang, J Zhao, P Chen, T Nakaguchi, D Grundy, and H Gregersen,
Aalborg, Aalborg, Denmark , Chiba, Japan, and Sheffield, United Kingdom. Mech-Sense, Aalborg
Hospital Program 193
122 EFFECT OF SYNTHETIC CATIONIC PROTEIN ON MECHANO-EXCITABILITY OF
ESOPHAGEAL VAGAL AFFERENT SUBTYPES. SY Yu and A Ouyang, Hershey, PA. Penn
State College of Medicine Program 194
Functional GI Disorders in Adults: Epidemiology, Genetics and Psychosocial Factors
123 IMPACT OF GLOBUS SENSATION ON SURVIVAL IN OLMSTED COUNTY,
MINNESOTA: A POPULATION-BASED STUDY. JY Chang, G Locke, CD Schleck, AR
Zinsmeister, and NJ Talley, Rochester, MN and Jacksonville, FL. Mayo Clinic Program 195
124 CYTOKINE EXPRESSION IN COLONIC MUCOSA AND PLASMA IN PATIENTS WITH
IRRITABLE BOWEL SYNDROME. R Choung, WA Faubion, YA Saito, A Malhotra, A
Mazzone, DR Linden, G Farrugia, GR Locke, AR Zinsmeister, and NJ Talley, Rochester, MN and
Jacksonville, FL. Mayo Clinic Program 196
125 AFTER AN INTESTINAL BACTERIAL INFECTION, 10 TO 30% OF PATIENTS,
PREDOMINANTLY WOMEN, REMAIN SYMPTOMATIC. P Enck, M Krieg, S
Klosterhalfen, IB Autenrieth, S Zipfel, and J Frick, Tuebingen, Germany. University Hospital
Tuebingen Program 197
126 HEALTHCARE RESOURCES UTILIZATION IN PATIENTS WITH NARCOTIC BOWEL
SYNDROME. T Esfandyari and K Roeser, Kansas City, KS. Kansas University Medical Center
Program 198
127 RAPID GASTRIC EMPTYING SHOULD BE A NEW SUPPORTING CRITERION FOR
THE DIAGNOSIS OF CYCLIC VOMITING SYNDROME IN ADULT PATIENTS.
RA Hejazi, T Lavenbarg, P Foran, and RW McCallum, El Paso, TX and Kansas City, KS. Texas
Tech University Health Sciences Center Program 199
128 ECONOMIC BURDEN OF IRRITABLE BOWEL SYNDROME IN KOREA; THE
ANALYSIS OF A NATIONAL HEALTH INSURANCE DATABASE COVERING THE
Poster No.
ENTIRE POPULATION. H Jung, Y Kim, J Park, B Jang, S Park, M Nam, and M Choi, Seoul,
Korea. Ewha Womans University Program 200
129 PERCEIVED SEVERITY OF TRAUMA NOT EXPOSURE OR NUMBER OF
TRAUMATIC EVENTS IS ASSOCIATED WITH PSYCHOSOCIAL AND PHYSICAL
COMPLAINTS OF SEVERELY AFFECTED IBS PATIENTS. JM Lackner, T Sapaleva, A
Smith, D Lauterbach, AM Brasel, C Radziwon, SS Krasner, and L Katz, Buffalo, NY and Ypsilanti,
MI. University at Buffalo, SUNY Program 201
130 NEURAL AUTOANTIBODY EVALUATION IN FUNCTIONAL GASTROINTESTINAL
DISORDERS: A POPULATION-BASED CASE-CONTROL STUDY. GR Locke, SJ Pittock,
VA Lennon, CL Dege, and NJ Talley, Rochester, MN. Mayo Clinic Program 202
131 TIC TAC DIARRHEA. S Misra, OJ Penaloza, MS Beede, and GA Marin, Trenton, NJ. Capital
Health Internal Medicine Residency Program Program 203
132 UTILIZATION OF MEDICINAL PLANTS AS A SOURCE OF MEDICINE FOR
GASTROINTESTINAL DISORDERS IN LAKSHMIPUR DISTRICT OF BANGLADESH.
MAH Mollik, Dhaka, Bangladesh. Peoples Integrated Alliance Program 204
133 HIGH MATERNAL PARITY HAD INCREASED BRISTOL ROME III-VECTOR BUT
NOT ABDOMINAL PAIN COMPARED WITH CAESAREAN SECTION PATIENTS. A
REPORT FROM THE MEXICAN IBS WORKING GROUP. G Ortiz-Luna, J Tamayo, J
Vargas, J Lopez-Alvarenga, Y Crespo, A Jiménez, A Saez, J Remes-Troche, and M Schmulson,
Naucalpan de Juarez, Naucalpan, and Veracruz, Mexico. Program 205
134 ASSOCIATION OF THE BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF)
Val66MET POLYMORPHISM AND IBS. GS Sayuk, VM Kushnir, P Kibe, A Sabzpoushan, B
Cassell, J Shroff, T Li, BD Nix, PJ Lustman, RD Newberry, E Li, and CP Gyawali, St Louis, MO.
Washington University Program 206
135 THE SEVERITY OF IBS SYMPTOMS IS RELATED TO THE PATIENT’S CHOICE OF
DIFFERENT MEDICAL SPECIALISTS. A REPORT OF THE MEXICAN IBS WORKING
GROUP. MJ Schmulson, JM Remes-Troche, J Vargas, J Lopez-Alvarenga, O Teramoto, Y Crespo,
A Jimenez, A Saez, and J Tamayo, Naucalpan de Juarez, Naucalpan, and Veracruz, Mexico.
Program 207
136 UNRAVELING THE COMPLEX INTERPLAY BETWEEN GASTRIC SENSITIVITY,
PSYCHOSOCIAL FACTORS, SOMATIC SYMPTOMS & QUALITY OF LIFE IN
FUNCTIONAL DYSPEPSIA (FD): A STRUCTURAL EQUATION MODELLING
APPROACH. L Van Oudenhove, MP Jones, L Holvoet, J Vandenberghe, R Vos, K Demyttenaere,
and J Tack, Leuven, Belgium and Sydney, Australia. University of Leuven Program 208
137 DISTINCT SYMPTOM FACTORS CORRESPONDING TO ROME III SUBGROUPS ARE
DIFFERENTIALLY ASSOCIATED WITH GASTRIC SENSORIMOTOR FUNCTION,
PSYCHOSOCIAL FACTORS AND ‘SOMATIZATION’ IN FUNCTIONAL DYSPEPSIA
(FD). L Van Oudenhove, L Holvoet, J Vandenberghe, R Vos, and J Tack, Leuven, Belgium.
University of Leuven Program 209
Gastric Physiology, Pathophysiology, and Clinical Disorders
Poster No.
138 RADIOGRAPHIC ANALYSIS OF GASTROINTESTINAL MOTOR FUNCTION IN TYPE
1 AND TYPE 2 DIABETIC RATS. R Abalo, PA Cabezos, G Vera, V López -Miranda, E
Herradón, and MI Martin, Alcorcón, Madrid, Spain. Universidad Rey Juan Carlos Program 210
139 HOURS OF NAUSEA AND NUMBER OF VOMITING EPISODES FOR ASSESSMENT OF
PATIENTS WITH GASTROPARESIS. D Cherian and HP Parkman, Philadelphia, PA. Temple
University Program 211
140 CD206 POSITIVE M2-MACROPHAGES ARE A MARKER OF DIABETIC
GASTROPARESIS IN db/db MICE, A MODEL OF TYPE 2 DIABETES. KM Choi, PC
Kashyap, N Dutta, DR Linden, T Ordog, JH Szurszewski, SJ Gibbons, and G Farrugia, Rochester,
MN. Mayo Clinic College of Medicine Program 212
141 THE CHANGES ON GASTRIC EMPTYING AND GASTRIC MYENTERIC NEURONS OF
RATS WITH IBS-C ---- THE UNDERLYING MECHANISM OF OVERLAPPING
SYNDROME. X Fang, X Yang, S Li, X Liu, L Zhu, and M Ke, Beijing, China Peking Union
Medical College Program 213
142 CERVICAL SPINAL CORD TRANSECTION (SCT) INCREASES GASTRIC
COMPLIANCE IN ANESTHETIZED RATS. SW Goiana, FA Gondim, FH Rola, AA Santos, G
Cristino-Filho, and JV Graça, Sobral, Ceará, Brazil and Saint Louis, MO. University Federal of
Ceará Program 214
143 THE EFFECTS OF ALCOHOL ON GASTRIC EMPTYING AND SYMPTOMS DURING
AND AFTER INGESTION OF A HIGH CALORIE, HIGH FAT SWISS FONDUE MEAL: A
RANDOMIZED CROSS OVER TRIAL. H Heinrich, O Goetze, D Menne, PX Iten, H Fruehauf,
M Fried, W Schwizer, and M Fox, Zurich and Tuebingen Germany. University of Zurich
Program 215
144 GASTRIC DYSMOTILITY IN AN ANIMAL MODEL OF TRAUMATIC BRAIN INJURY.
GM Holmes, E Qualls-Creekmore, and M Tong, Baton Rouge, LA. Louisiana State University
System Program 216
145 EARLY EFFECTS OF ORAL ADMINISTRATIONS OF OMEPRAZOLE WITH
MOSAPRIDE ON INTRAGASTRIC PH. H Iida, M Inamori, T Akiyama, Y Sakamoto, and A
Nakajima, Yokohama, Japan. Yokohama City University School of Medicine Program 217
146 DA 9701, A NEW PROKINETIC AGENT IMPROVES THE GASTRIC
ACCOMMODATION IN CONSCIOUS DOGS. E Kim, B Min, T Lee, M Son, and P Rhee,
Seoul, Korea Sungkyunkwan University Program 218
147 AZITHROMYCIN AND ERYTHROMYCIN EQUALLY IMPROVE GASTRIC EMPTYING
T1/2 IN ADULTS WITH GASTROPARESIS. JM Larson, A Tavakkoli, W Drane, P Toskes, and
B Moshiree, Gainesville, FL. University of Florida Program 219
148 POST-SURGICAL GASTROPARESIS: A MODERN DESCRIPTION. N Malhotra, M
Pathikonda, P Sachdeva, AH Maurer, RS Fisher, and HP Parkman, Philadelphia, PA. Temple
University Program 220
Poster No.
149 ALTERED EXPRESSION OF ANO1 SEGMENTS IN DIABETIC GASTROPARESIS.
A Mazzone, CE Bernard, LJ Galietta, PJ Pasricha, DR Linden, JH Szurszewski, T Ordog, SJ
Gibbons, and G Farrugia, Rochester, MN, Genova, Italy, and Stanford, CA. Mayo Clinic College of
Medicine Program 221
150 SPECTRAL ANALYSIS OF GI MOTILITY COMPARING VARIOUS GASTRIC
REGIONS. WL Michalek, K Chang, S Trial Group, and B Kuo, Boston, MA and Buffalo, NY.
Harvard Medical School Program 222
151 ANALYSIS OF UPPER GI MIGRATING MOTOR COMPLEXES USING INVASIVE AND
NON-INVASIVE TECHNIQUES. WL Michalek, B Kuo, and S Trial Group, Boston, MA and
Buffalo, NY. Harvard Medical School Program 223
152 OPTIMAL PRESSURE THRESHOLDS FOR UGI MOTILITY ASSESSMENT: INVASIVE
VS. NON-INVASIVE TECHNIQUES. WL Michalek, H Parkman, B Rohde, P Buckley, J Powers,
J Semler, and B Kuo, Boston, MA, Philadelphia, PA, and Buffalo, NY. Harvard Medical School
Program 224
153 INFLAMMATORY AND AUTOIMMUNE MARKERS IN DIABETIC AND IDIOPATHIC
GASTROPARESIS. HP Parkman, The NIH Gastroparesis Clinical Research Consortium,
Bethesda, MD. Temple University Program 225
154 NOVEL SENSING APPROACHES TO UNRAVEL THE MECHANISM THAT
REGULATES GASTRIC ACID SECRETION IN THE GUINEA PIG STOMACH. BA Patel
and E Bitziou, Brighton and Warwick, United Kingdom. University of Brighton Program 226
155 GASTRIC EMPTYING SCINTIGRAPHY: IS FOUR HOURS WORTH THE TIME?
M Pathikonda, P Sachdeva, N Malhotra, AH Maurer, RS Fisher, and HP Parkman, Philadelphia,
PA. Temple University Program 227
156 THE BILE SALT CHENODEOXYCHOLATE AND THE BILE ACID SEQUESTRANT
COLESEVELAM BOTH RETARD GASTRIC EMPTYING DESPITE OPPOSITE
EFFECTS ON COLONIC TRANSIT IN IBS PATIENTS. AS Rao, BS Wong, ST Odunsi-
Shiyanbade, D Burton, S McKinzie, AR Zinsmeister, and M Camilleri, Rochester, MN. Mayo
Clinic College of Medicine Program 228
157 REGULATION OF CIRCULATING ACYL AND DESACYL GHRELIN AFTER
ABDOMINAL SURGERY IN RATS AND POTENTIAL ROLE IN THE DEVELOPMENT
OF POSTOPERATIVE GASTRIC ILEUS. A Stengel, M Goebel, L Wang, JR Reeve, and Jr., Y
Taché, Los Angeles, CA. David Geffen School of Medicine at UCLA Program 229
158 THE EFFECT OF USING 5-HT AND ELECTRICAL STIMULATING ON THE MODLE
OF GASTRIC DYSRHYTHMIA RABBIT’S GASTRIC ELECTRIC ACTIVITY. H Zhang,
S Ouyang, WF Huang, and LC Li, Xiamen, China. Xiamen Medicine Research Institute
Program 230
GI Motility and Functional GI Disorders in Children and Adolescents
159 EFFECT OF AFLATOXIN B1 ON COLON MORPHOLOGY AND MOTILITY IN THE
MOUSE. FB Abdu, OA Abuzinadah, TR Rahmi, and MA Omran, Jeddah and Taief, Saudia Arabia.
King Abdulaziz University Program 231
Poster No.
160 ROLE OF MELATONIN IN COLONIC MOTILITY IN IRRITABLE BOWEL
SYNDROME- CONSTIPATION (MIMI-C)- A DOUBLE BLINDED RANDOMIZED
PLACEBO CONTROL CLINICAL TRIAL. P Basu, T Pacana, N Shah, H Hampole, N
Krishnaswamy, and K Rayapudi, Forest Hills, NY. Forest Hills Hospital Program 232
161 POSTNATAL NEUROGENESIS IN MYENTERIC PLEXUS OF THE GUINEA PIG
ILEUM. X Bian and M Kadrofske, E. Lansing, MI. Michigan State University Program 233
162 BOWEL HABITS IN ARGENTINE ADOLESCENTS: RESULTS OF A MULTICENTER
SURVEY. CG Boggio Marzet, MT Basaldúa, and V Plante, Buenos Aires, Argentina. Hospital
General de Agudos Program 234
163 IMPACT OF HIGH RESOLUTION ANORECTAL MANOMETRY IN CHILDREN.
BP Chumpitazi, Houston, Texas. Baylor College of Medicine Program 235
164 DEPRESSION, ANXIETY AND QUALITY OF LIFE ARE NOT CORRELATED TO
COLONIC 5-HT ALTERATIONS IN CHILDREN WITH IBS AND FAP. C Faure, E Brooks,
C Gauthier, and G Mawe, Montreal, Quebec, Canada and Burlington, VT. Sainte-Justine Research
Centre Program 236
165 GASTRIC EMPTYING AND SMALL INTESTINAL TRANSIT IN PATIENTS WITH
SPINAL CORD INJURY. L Fynne, J Worsoe, V Schlageter, S Laurberg, and K Krogh, Aarhus,
Denmark. Aarhus University Hospital Program 237
166 THERAPY OF FUNCTIONAL GASTROINTESTINAL DISEASES IN THE PEDIATRIC
POPULATION: REVIEW OF CLINICAL DATA FOR THE PHYTOMEDICINE STW 5.
KJ Gundermann, BR Vinson, O Kelber, and D Weiser, Szczecin, Poland and Darmstadt, Germany.
Pomeranian Medical Academy Program 238
167 ORTHOSTATIC INTOLERANCE AND ANTRODUODENAL DYSMOTIITY IN
ADOLESCENTS WHO MEET ROME III CRITERIA FOR CHRONIC ABDOMINAL PAIN
(CAP). PN Jhaveri, PB Jhaveri, and A Darbari, Baltimore, MD. Johns Hopkins University
Program 239
168 TOP DOWN MEDICAL TREATMENT FOR DISIMPACTION OF CHILDREN WITH
CHRONIC CONSTIPATION. J Jordan-Ely, JM Hutson, and BR Southwell, Parkville and
Melbourne, Australia. Advance-Wellness Continence Centre Program 240
169 TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION EFFECTS RECTAL
MOTILITY IN CHILDREN. I Moeller Joensson, S Hagstroem, C Siggaard, JC Djurhuus, and K
Krogh, Aarhus, Denmark. Aarhus University Program 241
170 RECURRENT ABDOMINAL PAIN IN INFANCY AND RISK OF RECURRENT
ABDOMINAL PAIN IN 12 YEAR-OLD SWEDISH CHILDREN. O Olen, JF Ludvigsson, I
Kull, M Wickman, and M Simren, Gothenburg and Stockholm, Sweden. Sahlgrenska Academy at
University of Gothenburg Program 242
171 LONGTERM OUTCOMES AND QUALITY OF LIFE IN CHILDREN WITH AN
ANTEGRADE CONTINENCE ENEMA (ACE). AA Siddiqui, S Fishman, S Bauer, and S Nurko,
Boston, MA. Harvard Medical School Program 243
Poster No.
172 CHRONIC CONSTIPATION WITH SMALL FREQUENT DEFECATIONS OCCURS IN
CHILDREN BUT DOES NOT FIT ROME III CRITERIA FOR FUNCTIONAL
CONSTIPATION. BR Southwell, KI Ismail, YI Yik, and JM Hutson, Parkville and Melbourne,
Australia and Kuala Lumpur, Malaysia. Murdoch Children’s Research Institute, Royal Children’s
Hospital Program 244
173 FINDINGS OF SIMULTANEOUS HIGH RESOLUTION MANOMETRY AND
VIDEOFLUOROSCOPY IN CHILDREN WITH ESOPHAGEAL SYMPTOMS. NA Tipnis,
CD Rudolph, and M Sood, Milwaukee, WI. Medical College of Wisconsin Program 245
174 INTRACTABLE CHRONIC CONSTIPATION WITH RAPID PROXIMAL COLONIC
TRANSIT MAY BE AN INDICATION OF FOOD INTOLERANCE. YI Yik, BR Southwell,
and JM Hutson, Parkville and Melbourne, Australia and Kuala Lumpur, Malaysia. Murdoch
Children’s Research Institute, Royal Children’s Hospital and University of Malaya Program 246
175 TARGETING THE CAUSES OF INTRACTABLE CHRONIC CONSTIPATION IN
CHILDREN: THE NUCLEAR TRANSIT STUDY (NTS). YI Yik, BR Southwell, and JM
Hutson, Parkville and Melbourne, Australia and Kuala Lumpur, Malaysia. Murdoch Children’s
Research Institute, Royal Children’s Hospital and University of Malaya Program 247
Gut Electrical Stimulation
176 MODULATING ENERGY SETTINGS TO DERIVE OPTIMAL EGG PARAMETERS IN
GASTROPARESIS. S Daram, C Lahr, DC Spree, A Kedar, and TL Abell, Jackson, MS.
University of Mississippi Medical Center Program 248
177 INFLUENCE OF THE ABDOMINAL TISSUE LAYERS ON EGG AND MGG SIGNALS.
JH Kim, LA Bradshaw, AJ Pullan, and LK Cheng, Auckland, New Zealand and Nashville, TN. The
University of Auckland Program 249
178 TRANSABDOMINAL ELECTRICAL STIMULATION THERAPY FOR SLOW-TRANSIT
CONSTIPATION (STC): FROM PHYSIOTHERAPY CLINIC-DELIVERED TO
PARENTAL HOME-DELIVERED TREATMENT. BR Southwell, YI Yik, and JM Hutson,
Parkville and Melbourne, Australia and Kuala Lumpur, Malaysia. Murdoch Children’s Research
Institute, Royal Children’s Hospital Program 250
179 SMALL INTESTINAL MOTILITY DURING SACRAL NERVE STIMULATION: A
STUDY WITH THE MOTILITY TRACKING SYSTEM MTS-1. J Worsoe, L Fynne, J Fassov,
N Rijkhoff, S Laurberg, and K Krogh, Aarhus and Aalborg, Denmark. Aarhus University
Program 251
Human Brain Mechanisms in Health and Disease
180 COMPARISON OF RESTING AND ACTIVE FUNCTIONAL CONNECTIVITY OF
SWALLOWING NETWORK. A Babaei, DB Ward, W Li, A Nencka, S Ahmad, M Kern, and R
Shaker, Milwaukee, WI. Medical College of Wisconsin Program 252
181 ALTERED EMOTIONAL MODULATION OF THE NEURAL RESPONSE TO VISCERAL
STIMULI IN IRRITABLE BOWEL SYNDROME. S Elsenbruch, C Rosenberger, U Bingel, M
Forsting, M Schedlowski, and ER Gizewski, Duisburg-Essen, and Hamburg, Germany. University
Hospital of Essen Program 253
Poster No.
182 BRAIN RESPONSE DURING EXPECTATION AND DELIVERY OF VISCERAL
STIMULATION DIFFERS BETWEEN IBS PATIENTS AND HEALTHY CONTROLS: AN
FMRI STUDY. M Larsson, K Tillisch, E Mayer, J Jarcho, J Labus, B Naliboff, P Lundberg, M
Ström, M Engström, and S Walter, Linköping, Sweden, and Los Angeles, CA. University of
Linköping Program 254
Neuroimmune Modulation
183 VAGAL INFLUENCE ON INDOMETHACIN INDUCED INTESTINAL INFLAMMATION
AND AFFERENT SENSITIVITY IN MICE. MS Kasparek, S Mittler, S Zedler, B Götz, MH
Müller, M Karpitschka, E Faist, and ME Kreis, Munich, Germany. Ludwig-Maximilian’s University
Program 255
184 THE EFFECT OF THE SEROTONIN PRECURSOR 5-HYDROXYTRYPTOPHAN ON
VISCEROPERCEPTION AND INTESTINAL PERMEABILITY IN HUMANS. D Keszthelyi,
FJ Troost, S Ludidi, H van Eijk, E Schaepkens, DM Jonkers, WA Buurman, J Dekker, and AA
Masclee, Maastricht and Wageningen, the Netherlands. Maastricht University Program 256
185 CHRONIC STRESS INCREASES PERIPHERAL PAIN SIGNALING IN A MOUSE
MODEL OF POST-INFECTIOUS IBS. F Ochoa-Cortes, C Ibeakanma, M Miranda-Morales, T
McDonald, IC Spreadbury, and SJ Vanner, Kingston, ON, Canada Queen's University
Program 257
186 A DIRECT INHIBITORY EFFECT OF BOTULINUM TOXIN TYPE A ON ANTRAL
CIRCULAR MUSCLE CONTRACTILITY OF GUINEA PIG. C Sohn, J Park, D Park, Y Cho,
H Kim, W Jeon, B Kim, P Rhee, M Park, and J Kwon, Seoul, Busan, and Daegu, Korea,.
Sungkyunkwan University Program 258
187 THE ROLE OF THE VAGUS NERVE IN THE IMMUNE RESPONSE TO TRICHINELLA
SPIRALIS INFECTION. SV Vaddi, P Blennerhassett, SM Collins, JL Pennock, and JA Miyan,
Manchester, United Kingdom and Hamilton, ON, Canada. University of Manchester Program 259
188 RELATIONSHIPS BETWEEN PSYCHOLOGICAL STRESS, GASTROINTESTINAL
SYMPTOMS AND PHYSIOLOGY, IMMUNE FUNCTION AND COAGULATION IN
PATIENTS WITH GASTROPARESIS AT TEMP GES. RB Vance, A Kedar, J Hughes, DC
Spree, M Griswold, and G Marshall, Jackson, MS. University of Mississippi Medical Center
Program 260
Pharmacotherapy and Pharmacogenomics
189 STW 5, A THERAPEUTIC AGENT USED IN IRRITABLE BOWEL SYNDROME (IBS), IS
ACTIVE AGAINST DEXTRAN SODIUM SULPHATE (DSS) INDUCED COLITIS. H Abdel-
Aziz, W Wadie, HF Zaki, O Kelber, D Weiser, and MT Khayyal, Cairo, Egypt and Darmstadt,
Germany. Heliopolis University Program 261
190 THE MECHANISMS OF THE ANTI-INFLAMMATORY ACTION OF THE
ANTIDYSPEPTIC DRUG STW 5 ARE DIFFERENT FROM THOSE OF NSAIDS.
GA Bonaterra, U Traut, O Kelber, SN Okpanyi, D Weiser, J Metz, and R Kinscherf, Mannheim,
Darmstadt, Heidelberg, and Marburg, Germany. University of Heidelberg Program 262
191 “IDIOPATHIC” GASTROINTESTINAL FAILURE – THE IMPORTANCE OF IDENTIFYING
AND TREATING PRIMARY PSYCHIATRIC CAUSES. JH Bourke, S, J Soldan, DB Silk, Q
Aziz, and G Libby, London, United Kingdom. SLAM NHS Foundation Trust Program 263
Poster No.
192 THE EFFECT OF ITOPRIDE ON DYSPEPTIC SYMPTOMS AND PATHOPHYSIOLOGIC
ABNORMALITIES IN THE PATIENTS WITH FUNCTIONAL DYSPEPSIA;
PRELIMINARY RESULTS. M Choi, C Lim, K Nam, Y Cho, J Park, I Lee, S Kim, K Choi, and I
Chung, Seoul, Korea. The Catholic University of Korea Program 264
193 CHRONIC CONSTIPATION IS MORE THAN JUST BOWEL SYMPTOMS: RESULTS
FROM QUALITATIVE PATIENT INTERVIEWS. S Fehnel, CM Ervin, SJ Shiff, JM Johnston,
CB Kurtz, and RT Carson, Cambridge, MA, Research Triangle Park, NC, and Jersey City, NJ.
Ironwood Pharmaceuticals, Inc. Program 265
194 THE USE OF AND BELIEFS ABOUT DIETARY SUPPLEMENTS AMONG PATIENTS
WITH GASTROPARESIS: A PILOT SURVEY. J Glisson, T Vesa, DC Spree, and TL Abell,
Jackson, MS. University of Mississippi Medical Center Program 266
195 RESULTS FROM TWO PHASE 3 CLINICAL TRIALS OF LINACLOTIDE IN PATIENTS
WITH CHRONIC CONSTIPATION (CC). AJ Lembo, H Schneier, BJ Lavins, SJ Shiff, JE
MacDougall, CB Kurtz, MG Currie, and JM Johnston, Cambridge, MA and Jersey City, NJ.
Ironwood Pharmaceuticals, Inc. Program 267
196 HISTAMINE-INDUCED INFLAMMATORY REACTIONS IN INTESTINAL MUCOSA:
INHIBITION BY STW 5. K Merkel, K Klein, D Jandaghi, BR Vinson, O Kelber, D Weiser, S
Laufer, and H Heinle, Tuebingen, Germany. University of Tuebingen Program 268
197 EFFECT OF METHYLNALTREXONE ALONE AND IN COMBINATION WITH
CODEINE ON GASTROINTESTINAL AND COLONIC TRANSIT IN HEALTH. BS Wong,
AS Rao, M Camilleri, N Manabe, S McKinzie, I Busciglio, D Burton, M Ryks, and AR Zinsmeister,
Rochester, MN. Mayo Clinic College of Medicine Program 269
198 PROKINETIC EFFECTS AND MECHANISMS OF A NEW 5-HT4 COMPOUND YKP10811
ON GASTRIC EMPTYING IN DOGS. J Yin, X Xu, H Han, H Kim, and J Chen, Galveston, TX,
Oklahoma City, OK, and Fair Lawn, NJ. University of Texas Medical Branch Program 270
199 EFFECTS OF A NEW 5-HT4 COMPOUND YKP10811 ON COLONIC TRANSIT IN DOGS.
J Yin, J Chen, L Lin, H Han, H Kim, and J Chen, Galveston, TX and Fair Lawn, NJ. University of
Texas Medical Branch Program 271
200 EVALUATION OF DOMPERIDONE-PIOGLITAZONE DRUG-DRUG INTERACTION IN
HUMAN LIVER MICROSOMES. A Youssef, A Argikar, HP Parkman, and S Nagar,
Philadelphia, PA. Temple University Program 272
Probiotics, and Gut Ecology in Health and Disease
201 IS SMALL BOWEL AND COLONIC MOTILITY ALTERED IN CONSTIPATED
PATIENTS WITH METHANOGENIC FLORA? A Attaluri, J Valestin, and S Rao, Iowa City,
IA. University of Iowa Program 273
202 COMPARATIVE ANALYSIS OF A HIGHLY DIVERSE SET OF BIFIDOBACTERIA AND
LACTOBACILLI USING IN VITRO CELLULAR MODELS TOWARDS AN
ALLEVIATION OF IBS SYMPTOMS. M Neunlist, B Lesic, M Ribeiro Da Silva, S Capronnier,
E Supply, S Fortin, V Sanchez, I Tiscornia, M Biraud, I Chambaud, T Smokvina, P Rondeau, M
Bollati, S Legrain-Raspaud, and G Grompone, Paris, Palaiseau, Nantes, France, and Montevideo,
Uruguay. Danone Research Program 274
Poster No.
203 LACTOBACILLUS GG PROTECTS FROM FRUCTOSE INDUCED HEPATIC LIPID
ACCUMULATION IN MICE. Y Ritze, A Hubert, A BSuerlein, A Spruss, B Wendt, I Bergheim,
and SC Bischoff, Stuttgart, Germany. University of Hohenheim Program 275
204 UNEXPLAINED, SELF-REPORTED FOOD HYPERSENSITIVITY: A FERMENTATION
PROBLEM? J Valeur, MH Morken, E Norin, T Midtvedt, and A Berstad, Bergen, Norway and
Stockholm, Sweden. University of Bergen Program 276
Psychological and Alternative Therapeutics
205 IMPACT OF A GI MIND BODY INTERVENTION (MBI) UPON MIXED GROUP OF
PATIENTS WITH IRRITABLE BOWEL SYNDROME AND INFLAMMATORY BOWEL
DISEASE. B Kuo, A Dassatti, N Hasheminejad, A Thurler, J Rosenblum, L Kagan, H Benson, G
Fricchione, J Denninger, EA Slawsby, M Brun, B Norton, S Rao, and JR Korzenik, Boston, MA,
Harvard Medical School Program 277
206 A PRELIMINARY RESEARCH STUDY OF PLANTS USED AS REMEDY FOR END OF
LIFE CARE OF TERMINALLY ILL PATIENTS IN NARAIL DISTRICT OF
BANGLADESH. M Mollik, Dhaka, Bangladesh. Peoples Integrated Alliance Program 278
Signaling: Hormones, Neurotransmitters, Receptors, Channels, Secondary Messengers
207 REGULATION OF COLONIC LONGITUDINAL MUSCLE CONTRACTION BY ERK1/2
AND RHO KINASE. CD Anderson, S Mahavadi, KS Murthy, and JR Grider, Richmond, VA.
Virginia Commonwealth University Program 279
208 TRANSIENT RECEPTOR POTENTIAL VANILLOID TYPE 4 (TRPV4) SLOWS
MOTILITY AND REDUCES EPITHELIAL ION TRANSPORT IN THE MOUSE COLON.
J Fichna, D Saur, KS Thorneloe, J Timmermans, and MA Storr, Calgary, AB, Canada, Munich,
Germany, King of Prussia, PA, and Antwerp, Belgium. University of Calgary Program 280
209 ASSESSMENT OF PLASMA CONCENTRATIONS OF GLUCAGON-LIKE PEPTIDE:
BLOOD PROCESSING IS CRITICAL. M Goebel, A Stengel, Y Taché, R Reidelberger, A
Haver, and JR Reeve, Jr., Los Angeles, CA and Omaha, NE. David Geffen School of Medicine at
UCLA Program 281
210 NEUROPEPTIDE S DISRUPTS THE MIGRATING MYOELECTRIC COMPLEX AND
INDUCES SPIKE BURSTS AS AN INTESTINAL INFLAMMATORY MARKER
RESPONSE IN THE SMALL INTESTINE OF THE RAT. PM Hellström, T Rudholm, and L
Gillberg, Uppsala, Sweden. Uppsala University Program 282
211 QUERCETIN RELAX COLON SMOOTH MUSCLE OF GUINEA-PIG VIA THE
INTERACTION OF GC AND COX STIMULATION, AS WELL AS THE ANTAGONISM
EFFECT ON ACETYLCHOLINE. WF Huang, S Ouyang, H Zhang, and CJ Lu, Xiamen, Fujian
Province, China. Xiamen Medical Research Institute Program 283
212 GASTROINTESTINAL TRANSIT IS NOT ALTERED IN MALE OR FEMALE
SEROTONIN TRANSPORTER KO RATS. R Kabeer, B Patel, H Zhao, G Swain, and JJ
Galligan, East Lansing, MI. Michigan State University Program 284
Poster No.
213 DOWN-REGULATION OF -ARRESTIN EXPRESSION IN THE GUINEA-PIG ILEUM
BUT NOT THE COLON CORRELATES WITH MORPHINE TOLERANCE.
M Kang, HM Payne, WL Dewey, and HI Akbarali, Richmond, VA. Virginia Commonwealth
University Program 285
214 CORTISTATIN INHIBITS INTESTINAL SECRETION IN THE GUINEA PIG ILEUM IN
VITRO. S Liu, W Ren, and JD Wood, La Crosse and Columbus, OH. University of Wisconsin-La
Crosse Program 286
215 PHARMACOLOGY OF NICOTINIC RECEPTOR MEDIATED RELAXATION IN
HUMAN GASTRIC CLASP AND SLING MUSCLE FIBERS. LS Miller, MR Ruggieri, AK
Vegesna, AS Braverman, MI Tiwana, and SB Gottimukkla, Bala Cynwyd and Philadelphia, PA.
Temple University Program 287
216 LOCALIZATION OF NICOTINIC RECEPTOR SUBUNITS IN HUMAN CLASP FIBERS
USING IMMUNOFLUORESCENCE. LS Miller, MF Barbe, AS Braverman, AK Vegesna, and
MR Ruggieri, Bala Cynwyd and Philadelphia, PA. Temple University Program 288
217 ALPHA-SYNUCLEIN IS INDUCED BY DEPOLARIZATION AND CAMP IN ENTERIC
NEURONS. S Paillusson, T Lebouvier, J Chevalier, M Neunlist, and P Derkinderen, Nantes,
France. Inserm Program 289
218 MUCOSAL SEROTONIN AVAILABILITY IS INCREASED IN AGED MURINE COLON
DUE TO IMPAIRED SEROTONIN RE-UPTAKE. BA Patel, H Zhao, GM Swain, JJ Galligan, X
Bian, and MS Yeoman, Brighton, United Kingdom and East Lansing, MI. University of Brighton
Program 290
219 A NOVEL ELECTROANALYTICAL APPROACH FOR STUDYING THE REGULATION
OF RELEASE AND RE-UPTAKE OF SEROTONIN FROM EC CELLS. BA Patel and G
Marcelli, Brighton and London, United Kingdom. University of Brighton Program 291
220 MORPHINE-INDUCED TOLERANCE DOES NOT ALTER CHOLINERGIC
CONTRACTIONS IN THE MOUSE ILEUM AND COLON. GR Ross, WL Dewey, and HI
Akbarali, Richmond, VA. Virginia Commonwealth University Program 292
221 GSK962040: A SMALL MOLECULE MOTILIN RECEPTOR AGONIST WHICH
INCREASES GASTROINTESTINAL (GI) MOTILITY IN DOGS. GJ Sanger, J Broad, S
Leming, KL Matthews, M Briggs, M Otterson, W Winchester, SJ Cozens, GE Dukes, and K Lee,
London, United Kingdom, Milwaukee, WI, and Research Triangle Park, NC. Queen Mary
University of London Program 293
222 DIFFERENT ABILITIES OF [NLE13]-MOTILIN AND THE MOTILIN RECEPTOR
AGONIST GSK962040 TO FACILITATE CHOLINERGIC AND NITRERGIC ACTIVITY
IN HUMAN ISOLATED STOMACH. GJ Sanger, J Broad, S Mukherjee, G Boundouki, and GE
Dukes, London, United Kingdom and Research Triangle Park, NC. Queen Mary University of
London Program 294
223 ROLES OF ENDOGENOUS AND EXOGENOUS GHRELIN IN REGULARING GASTRIC
TONE, COMPLIANCE AND ACCOMMODATION IN DOGS. Y Sun, G Song, and J Chen,
Oklahoma City, OK and Houston, TX. Research Foundation, VA Medical Center Program 295
Poster No.
224 BI-DIRECTIONAL REGULATION BY TACHYKININ NK2-RECEPTOR ON MOTOR
RESPONSE IN SMOOTH MUSCLE PREPARATIONS OF ISOLATED HUMAN COLON.
Y Tsukimi, A Nakamura, G Mizojiri, and M Toyoda, Osaka, Japan. Takeda Pharmaceutical
Company Program 296
Smooth Muscle and Interstitial Cells of Cajal in Health and Disease
225 WNT-INDUCED EXHAUSTION OF INTERSTITIAL CELL OF CAJAL (ICC) STEM
CELLS UNDERLYING AGING-ASSOCIATED ICC LOSS DOES NOT DEPEND ON
MTOR SIGNALING AND MAY BE MEDIATED BY PERSISTENT CATENIN
ACTIVATION. DT Asuzu, Y Hayashi, MR Bardsley, RA Urrutia, G Farrugia, and T Ordog,
Rochester, MN. Mayo Clinic College of Medicine Program 297
226 GASTRIC EXPRESSION OF THE ANTI-AGING PROTEIN KLOTHO PROTECTS ICC
FROM OXIDATIVE STRESS. MR Bardsley, A Lorincz, K Choi, DT Asuzu, F Izbeki, DL
Young, LN Popko, Y Hayashi, M Kuro-o, G Farrugia, and T Ordog, Rochester, MN and Dallas,
TX. Mayo Clinic College of Medicine Program 298
227 FUNCTIONAL EVIDENCE FOR DECREASED PLATELET-DERIVED GROWTH
FACTOR (PDGF) RECEPTOR ACTIVATION IN CULTURED LOWER ESOPHAGEAL
SPHINCTER (LES) CIRCULAR SMOOTH MUSCLE CELLS (CSMC) FROM WWV
MUTANT MICE. F Bautista-Cruz and WG Paterson, Kingston, Ontario, Canada. Queen's
University Program 299
228 COMPARISON OF THE MORPHOLOGICAL AND FUNCTIONAL PROPERTIES OF
THE INTERNAL ANAL SPHINCTER IN WILD TYPE MICE (C57BL/6) AND MICE
CONTAINING THE REDUCED FUNCTION KIT ALLELE (WV). CA Cobine, A Duffy, W
Yan, SM Ward, KM Sanders, and KD Keef, Reno, NV. University of Nevada, Reno Program 300
229 A MATHEMATICAL MODEL OF ACTIVE FORCE PRODUCTION IN GASTRIC
SMOOTH MUSCLE CELLS. V Gajendiran and ML Buist, Singapore. National University of
Singapore Program 301
230 INHIBITION OF GLYCOGEN SYNTHASE KINASE-3 (GSK-3) MIMICS INSULIN-LIKE
GROWTH FACTOR-I (IGF-I)-INDUCED STEM CELL FACTOR (SCF) EXPRESSION IN
THE MURINE STOMACH. Y Hayashi, KH Aarsvold, MR Bardsley, SJ Gibbons, and T Ordog,
Rochester, MN. Mayo Clinic College of Medicine Program 302
231 ALTERATIONS IN SPONTANEOUS CONTRACTIONS AND CONTRACTILE
RESPONSES TO CARBACHOL AND SNP IN GASTRIC ANTRUM OF PATIENTS WITH
DIABETES MELLITUS. J Kwon, D You, H Chae, C Cho, H Sung, K Park, and T Kim, Daegu,
Korea. Catholic University of Daegu Program 303
232 ELECTROPHYSIOLOGICAL PROPERTY OF PACEMAKER POTENTIAL IN HUMAN
GASTRIC FUNDUS. J Lee, E Ko, B Min, SM Ward, S Koh, and P Rhee, Seoul, Korea and Reno,
NV. Sungkyunkwan University Program 304
233 A CASE OF ENTERIC DYSMOTILITY AND LOSS OF INTRAMUSCULAR
INTERSTITIAL CELLS OF CAJAL. M Li, B Riddell, A Okrainec, and LW Liu, Toronto,
Canada. University of Toronto Program 305
Poster No.
234 MECHANO-REGULATION OF GENE EXPRESSION UNDERLIES MOTILITY
DYSFUNCTION IN BOWEL OBSTRUCTION. YM Lin, SK Sarna, and XP Shi, Galveston, TX.
University of Texas Medical Branch Program 306
235 IDENTIFICATION OF THE SIGNALING MECHANISMS THAT MEDIATE
HYPERCONTRACTILITY OF COLONIC LONGITUDINAL MUSCLE DURING
INFLAMMATION: ACTIVATION OF MLCK VIA NF-B/PKA/AMPK PATHWAY.
S Mahavadi, CD Anderson, O AlShboul, JF Kuemmerle, KS Murthy, and JR Grider, Richmond,
VA. Virginia Commonwealth University Program 307
236 DECREASED CONTRACTILE RESPONSE OF GASTRIC CLASP AND LOWER
ESOPHAGEAL CIRCULAR MUSCLE STRIPS IN-VITRO IN BARRETT’S ESOPHAGUS
COMPARED TO NORMAL SUBJECTS. LS Miller, AK Vegesna, AS Braverman, MI Tiwana, E
Miller, and MR Ruggieri, Bala Cynwyd and Philadelphia, PA. Temple University
Program 308
237 A NOVEL POSTNATAL ANIMAL MODEL TO STUDY GASTROSCHISIS-RELATED
GUT DYSFUNCTION. SD Moore-Olufemi, SK Shah, H Xue, F Jimenez, PA Walker, and CS Cox,
Houston, TX. The University of Texas Medical School-Houston Program 309
238 QUANTIFYING A GASTROINTESTINAL SODIUM CHANNELOPATHY. YC Poh and ML
Buist, Singapore. National University of Singapore Program 310
239 IC CILIOME: MARKERS FOR PRIMARY CILIUM IN MOUSE KIT-IR INTERSTITIAL
CELLS OF CAJAL. J Vanderwinden, S Ralea, P Gromova, and P Hague, Brussels, Belgium.
Faculté de Médecine Program 311
240 CONTRACTILE RESPONSE OF PORCINE ESOPHAGEAL MUSCULARIS MUCOSA.
AK Vegesna, MI Tiwana, AS Braverman, LS Miller, and MR Ruggieri, Bala Cynwyd and
Philadelphia, PA. Temple University Program 312
241 REGIONAL DIFFERENCES IN DESCENDING INHIBITION TO COLONIC CIRCULAR
SMOOTH MUSCLE (CSM) OF W/WV MUTANT MICE. Y Zhang and WG Paterson, Kingston,
Ontario, Canada. Queen's University Program 313
