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  Professor David C.Y. Kwan, Ph.D.
                                  Department of Medicine, Faculty of Health Sciences
                                  McMaster University, Hamilton, Ontario, Canada
                                  Dept. Medicine, China Medical Univer. .Taichung, Taiwan
                                  Director, Center for Faculty Development
                                  Director, Center for International Affairs.
                                  Ph.D. (1976) Biol. Chem., Univ. Penn., Phila., Pa., USA
                                  M.Sc. (1971) Physic. Chem., Wilkes Univl., Pa. USA
                                  B. Sc. (1969) Chemistry, Chu-Hai Coll., Hong Kong
                                  Canada’s Who’s Who; Names in Hong Kong (China)
                                  Excellent Teaching Assistant Award in Chemistry (1974)
                                  Young Investigator Award, Canadian Hypertension Society. (1987)
                                  Ontario Heart Foundation Fellowship Awards (1981-1988)
                                  Career Investigator Award Canadian Heart & Stroke Foundation. (1989-99)
     www.kwancy.com               Excellent Tutor Award, Undergrad. MD program, McMaster (2002)

        Assist. Professor (1980); Assoc. Professor (1984); Tenured Full Professor (1988)

         Professor Kwan is a basic research scientist               Prof. Kwan has practiced problem-based
specializing in cardiovascular sciences. He was            learning (PBL) as a tutor in medical education at
originally trained as a physical chemists and              McMaster University for nearly two decades. He is an
biological chemists during his graduate studies.           award-winning tutor and a dedicated PBL advocate.
Since 1976, his research interest has spanned across       He helped introduce PBL to the medical faculty of the
the boundaries of molecular pharmacology, cellular         University of Hong Kong since 1994 and a hybrid
physiology and natural product research including          model of PBL curriculum was launched in 1997 there.
Chinese medicine, with an emphasis on cellular             In 2000, Prof. Kwan also helped the Faculty of
regulation of calcium and cell signaling processes.        Medicine of the National University of Singapore
He is a founding member of the Smooth Muscle               develop a hybrid PBL curriculum. He has traveled
Research Program of McMaster University. He also           several times to four major medical schools in
helped build the Institute of Cardiovascular Sciences      Malaysia helping with the development of PBL. He
and Medicine at the University of Hong Kong when           remains active in the Asia Pacific region towards
he was the Chair of Physiology there during 1992-          promotion of both medical education and research. He
1996. To this date, Prof. Kwan has published nearly        is instrumental in advocating PBL for medical
350 full-length papers (excluding abstracts)               education reform in this region spanning from Japan to
including 25 book chapters and proceeding papers.          Singapore. He also served as a PBL advisor/consultant
He has trained numerous research students and              for many medical schools in this region. In 2003, he
postdoctoral fellows coming from many countries of         served as a short-term PBL consultant in the
the world. He serves as a member on the Editorial          Philippines commissioned by WHO Western Pacific
Advisory Board of several international journals.          Regional Office in Manila. In 2004, Prof. Kwan spent
For >2 decades, He serves as a reviewer for                6-month sabbatical leave as a Visiting Professor of
manuscripts, international research granting agencies      Andrew T. Huang Fund for Promotion of Medical
(Canada, US, Singapore, Hong Kong), graduate               Education in Taiwan, where he continues to advocate
theses and academic promotions worldwide. He has           the benefit of PBL in medical education. He has now
been honored with Visiting Professorship in 10 top         joined China Medical University in Taiwan and is
medical universities in China, the University of           actively promoting medical education reform in the
Hong Kong, the National University of Singapore,           Asia Pacific region, including China. In 2006, he has
the National Defense Medical University, Fu-Jen            been the speaker on PBL and medical education in
Catholic University in Taiwan and University               International meetings, such as IUPHAR and FAOPS.
Automatic of Central America in Costa Rica.
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Recent typical publications: Medical Education:            Recent typical publications: Biomedical Sciences:

1. Kwan, C.Y. A Barnett, J. Ceaser, A. Cunje, P.           1. Grover AK, Samson SE, Robinson S, Kwan CY..
    Gamble, A. Hall and P. Krongold. Learning dynamics         Effects of peroxynitrite on sarcoplasmic reticulum
    in Problem-based Learning (PBL): Perspectives form         Ca2+-pump in pig coronary artery smooth muscle.
    McMaster medical students. J. Med. Edu. (Taiwan) 4         Am J Physiol, 284:C294-301, 2003.
    (2): 1-9, 2000.                                        2. Achike FI, Kwan CY. Nitric oxide, human
2. Kwan, C.Y. Medically related cultural issues can            diseases and herbal products that act on NO
    be learned by students and need not be taught by           pathway. Clin Expt Physiol Pharmacol 30: 605-
    teachers in a course. Acad. Medicine, 76:1-3, 2001.        615, 2003.
3. Kwan, C.Y.          Is PBL a quality approach to        3. Kwan, CY, Kwan TK, Zhang WB, Sakai Y. In
    education in health sciences? Ann. Acad. Med.              vitro relaxation of vascular smooth muscle by
    Singapore, 30: 341-346, 2001.                              atropine: involvement of K+-channels and
4. Kwan C.Y. (tutor), H. Jamal, N. Jha, M. Kapoor, S.          endothelium.      Naunyn-Schimedeberg’s Arch
    Katyal, J. Kelly, F. Khan and N. Muhn (mentor)             Pharmacol., 368: 1-9, 2003.
    Problem-based Learning in medicine: the first 12       4. Kwan CY, Zhang WB, Deyama T, Nishibe S.
    weeks of tutorial. J. Med. Educ. 5: 372-381, 2001.         Eucommia aqueous extract induces endothelium-
5. Kwan, C.Y. A note of caution in conducting PBL              dependent relaxation in rat aorta and mesenteric
    tutorials: observations in a medical school that           artery. Naunyn-Schmiedeberg’s Arch Pharmacol.
    newly adopted a PBL curriculum. J. Med. Educ. 5:           369: 206-211,2004.
    87-93, 2001.                                           5. Zheng WB, Chen CX, Sim SM, Kwan CY. In
6. Kwan, C.Y. Problem-based learning: properly                 vitro vasodilator mechanisms of indole alkaloids,
    balanced learning? Trends in Pharmacol Sci.,               rhynchophylline and isorhychophylline, isolated
    23:163-164, 2002.                                          from the hook of Uncaria rhychophylla (Miquel).
7. Kwan, C.Y. Problem-based learning and teaching              Naunyn-Schmiedeberg’s Arch Pharmacol 369:
    of medical pharmacology. Naunyn-Schmiedeberg’s             232-238, 2004.
    Arch. Pharmacol., 366:10-17, 2002.                     6. Kwan CY, Zhang WB, Sim SM, Deyama T,
8. Kwan CY. Teaching of human physiology as it                 Nishibe S. Vascular effects of Siberian ginseng
    relates to changes in medical education: An Asian          (Eleutherococcus      senticosus):    endothelium-
    perspective based on the yin-yang principle. J Med         dependent NO- and EDHF-mediated relaxation
    Educ 6: 449-460, 2002.                                     depending on vessel size. Schmiedeberg’s Arch
9. Kwan, C.Y. (tutor), T. Griffin, A. Hosein, K.               Pharmacol. 369: 473-480, 2004.
    Howell, J. Huber-Okrainec Y. Hussain. Students’        7. Younglai EV, Kwan T, Kwan CY, Lobb DK,
    perspectives on early clinical exposure during the         Foster WG. Dichlorodiphenylchloro-ethylene
    first twelve weeks of medical education at McMaster        elevates cytosolic calcium concentrations and
    University. J. Med. Educ. 7: 3-14, 2003.                   oscillations in cultured human granulose cells.
10. Kwan, C.Y. So, you will be a PBL tutor in a                Biol Reprod 70: 1693-1700, 2004.
    medical school. J. Med. Educ. 7: 313-322, 2003.        8. Younglai EV, Wu YJ, Kwan TK, Kwan CY.Non-
11. Kwan, C.Y. Learning of medical pharmacology via            genomic action of estradiol and progesterone on
    innovation: a personal experience at McMaster and          cytosolic calcium concentrations in primary
    in Asia. Acta Pharmacol Sinica 25: 1186-1194,              cultures of human granulosa-lutein cells. Hum
    2004.                                                      Reprod. 20:2383-2390, 2005.
12. Song G, Kwan CY, Bian Z, Tai B, Wu Q.                  9. Kwan CY, Zhang WB, Nishibe S, Seo S. A novel
    Exploratory thoughts concerning educational reform         in vitro endothelium-dependent vascular relaxant
    with problem-based learning in China. Teach Learn          effect of Apocynum venetum leaf extract.
    Med. 17:382-384, 2005.                                     Clin Exp Pharmacol Physiol. 32:789-795, 2005.
13. Kwan CY, Chang YH. PBL: education reform in            10. Davis KA, Samson SE, Best K, Mallhi KK,
    Chinese and Western medicine. Huaxia Med.1:180-            Szewczyk M, Wilson JX, Kwan CY, Grover
    182, 2006.                                                 AK.Ca(2+)-mediated ascorbate release from
14. Huang C, Bian Z, Tai B, Fan M, Kwan CY. Dental             coronary artery endothelial cells. Br J Pharmacol.
    education in Wuhan, China: challenges and changes. J       147:131-319, 2006.
    Dent Educ. 71:304-11. 2007                             11. Jassen LT, Kwan CY. ROCs and SOCs: what is
                                                               in a name? Cell Calcium 41: 245-247, 2006.

				
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