Chemistry 260 (2008) – Course Outline For Organic Chemistry, Seventh Edition, by John McMurry
NOTE: The student should make good use of Appendix C of the textbook (pp A10-29), which contains a very useful glossary of terms used in organic chemistry. Chapter 1 Structure and Bonding. Sections: 1-10. Lewis dot structures; Hybridization and geometry about atoms in organic molecules. Chapter 2 Polar Covalent Bonds; Acids and Bases. All sections. Dipole moments; formal charges; pKa considerations; resonance. Chapter 3 Organic Compounds: Alkanes and Their Stereochemistry. All Sections. Isomers; IUPAC nomenclature; Conformational analysis; torsional and steric strain; properties of hydrocarbons; other functional groups. Chapter 4 Organic Compounds: Cycloalkanes and Their Stereochemistry. Sections: 1-8. Angle strain; chair cyclohexane, axial and equatorial substituents: ring-flipping. Chapter 9 Stereochemistry. Sections: 1-7 and 9. Enantiomers, optical activity, R &S nomenclature, diastereomers, meso compounds, cis-trans stereoisomerism. Chapter 11 Reactions of Alkyl Halides: Nucleophilic Substitutions and Eliminations. Sections: 1-5, 7-10 and 12. SN2, SN1, E2, and E1 reactions with stereochemical consequences. Mechanisms, transition states, and intermediates. Chapter 6 Alkenes: Structure and Reactivity. Sections: 1-9. Nomenclature; stability; electrophilic addition, Markovnikov rule. Chapter 7 Alkenes: Reactions and Synthesis. Sections: 1-4, 7, 10. Halogenation; hydration; dehydrogenation; polymerization Chapter 15 Benzene and Aromaticity. Sections: 1-4. Aromatic stability, 4n+2 rule Chapter 16 Chemistry of Benzene. Sections 1-3. Electrophilic aromatic substitution Chapter 17 Alcohols and Phenols. Sections: 4,5,7. Reductions, Oxidations, Grignard Reactions Remaining Chapters: Sections to be announced. Aldehydes; ketones; carbohydrates esters; polyester, soap; amides; proteins