Do Asthma Prevalence and Childhood Lymphoblastic Leukemia Incidence Vary As a Function of Air Hazards by CDCdocs


Do Asthma Prevalence and Childhood Lymphoblastic Leukemia Incidence Vary As a Function of Air Hazards?

Advance Environmental Public Health Science and Research

asthma, ALL, ozone, PM<2.5, GIS

Our understanding of the spatial epidemiology of asthma and ALL is limited.

Determine if there were spatial associations between asthma, ALL, two outdoor air hazards, and one proxy for indoor air

Data layers for air hazards and chronic diseases were concatenated in a tracking GIS. Chronic disease data on 0–14 year
olds and air hazard data for 2000–2002 were used. Asthma prevalence was based on emergency room visits and inpatient
discharges for patients with an ICD-9 CM diagnosis of 493. Incidence for ALL was determined for patients with an ICD-
9-CM diagnosis of 204.0. Ozone and PM<2.5 monitors provided hourly mean and maximum readings. Data from the
2000 U.S. Census were used to determine housing age and value per zip code. Zip codes with a preponderance of
undervalued older units were classified as having worse indoor air than zip codes with overvalued newer units. Three-
digit zip codes were used for all analyses. ArcGIS 9 was the GIS. Descriptive statistics were computed using PC SAS
version 9.

Descriptive statistical and spatial analyses will be carried out on the linked data layers, either in SAS or by using GIS. We
expect asthma prevalence to be higher in zip codes with more air hazards. Additional analyses will determine if there are
spatial associations between asthma and ALL, and if these correlations differ as a function of air hazard concentrations.

This study should produce new information about the contribution of air hazards to asthma prevalence and determine the
spatial association between asthma and ALL. Anticipated results could be used to determine where public health
intervention programs should be implemented.

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John T. Braggio, Ph.D., M.P.H.
EPHT Coordinator/Epidemiologist
Maryland Department of Health and Mental Hygiene
Suite 1202, 6 Saint Paul Street
Baltimore, Maryland 21202

Rashid Malik:
Tanesha Johnson-Bey:

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