PROGRAM FOR THE INERNATIONAL SYMPOSIUM ON ALPD AND CIRRHOSIS

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PROGRAM FOR THE 2ND INERNATIONAL SYMPOSIUM ON ALPD AND CIRRHOSIS ORAL SESSIONS October 18, 2007 Welcoming Remarks 9:00-9:05 Shigeki Arii, President, the 11th General Meeting for JSH Ting-Kai Li, Director, NIAAA/NIH (Bethesda) Special Opening Lecture 9:05-9:25 Session 1: Cell Death and Survival (9:30-12:00) Chaired by Stephen Pandol (Los Angeles) and Michio Imawari (Tokyo) Jose C. Fernandez-Checa (Barcelona) Cheng Ji (Los Angeles) Anna Gukovskaya (Los Angeles) Ole Petersen (Liverpool) Fred Gorelick (West Haven) Ashok Saluja (Minneapolis) Cholesterol and sphingolipids in alcohol-induced liver injury Dissection of ER stress signaling in alcoholic and nonalcoholic liver Injury Death responses in pancreatitis: role of ethanol Ca2+-induced cell death: the roles of the ER, ZGs, lysosomes and endosomes Measure for measure: what injures cells and what is cell injury? Dual roles of HSP 70 in pancreatic diseases Luncheon Seminar (David Brenner) (12:30-13:40) Poster Session 1 (13:50-15:00) Session 2: Oxidant Stress and Inflammation (15:15-16:55) Chaired by Samir Zakhari (NIAAA/NIH, Bethesda) and Dong Xie (Shanghai) Craig McClain (Louisville) Laura Nagy (Cleveland) Gavin Arteel (Louisville) Jose M. Mato (Bizkaia) Nutrition and alcoholic liver disease: the role of Sadenosylmethionine and zinc Mechanisms for the anti-inflammatory effects of adiponectin in macrophages PAI-1 in alcohol-induced liver damage: new slices of the 'PAI'" Methionine metabolism in ASH and NASH Session 3: Clinical Research on Alcoholic Liver and Pancreatic Diseases (17:05-18:20) Chaired by Stephen Pandol (Los Angeles) and Norifumi Kawada (Osaka) Philippe Mathurin (Lille) Jeremy Wilson (Sydney) Treatment of severe forms of alcoholic hepatitis: where are we going? Individual susceptibility to alcoholic pancreatitis Katsuya Maruyama (Kurihama) Association analysis among polymorphisms of the various genes and chronic alcoholic pancreatitis October 19, 2007 Session 4: Metabolism, Cancer, and Genetics (9:00-11:05) Chaired by Hiromasa Ishii (Tokyo) and Manfred Singer (Mannheim) Shelly C. Lu (Los Angeles) Yutaka Kohgo (Asahikawa) Tooru Shimosegawa (Sendai) Kazuhiko Koike (Tokyo) Mimi C. Yu (Minneapolis) SAMe in cell growth, apoptosis and cancer Dysregulation of systemic iron metabolism in alcoholic liver diseases Alcoholic and genetic backgrounds for pancreatitis in Japan HCV, metabolism, and alcohol Alcohol, cofactors, and the genetics of hepatocellular carcinoma Break (11:05-11:20) Session 5: Stellate Cell Biology and Fibrosis (11:20-12:10) Chaired by Gamal Esmat (Cairo) and Terumi Takahara (Toyama) David Brenner (La Jolla) Hide Tsukamoto (Los Angeles) Innate immunity and reactive oxygen species in hepatic stellate cells Fat paradox of steatohepatitis Luncheon Seminar (Stephen Pandol) (12:30-13:40) Poster Session 2 (13:50-15:00) Session 6: Stellate Cell biology and Fibrosis -continued (15:15-16:55) Derek Mann (Newcastle Upon Tyne) Bin Gao (NIAAA, Bethesda) Kyoko Shimizu (Tokyo) Steven Dooley (Mannheim) Session 7: Global Networking (17:00-17:20) Chaired by Hide Tsukamoto (Los Angeles) Bertrand Nalpas (INSERM, Paris) Jose Mato (Bizkaia) INSERM Alcohol Research Program 2008 Symposium in Bilbao, Spain Epigenetic regulation of hepatic stellate cell activation Innate immunity and alcoholic liver fibrosis Pancreatic stellate cell: molecular mechanism of pancreatic fibrosis TGFβ effects in progression of chronic liver disease Open Discussions Closing Remarks Yutaka Atomi, Director General, JSG POSTER SESSIONS Posters can be viewed all day for two consecutive days. Parallel poster presentation will be held between 13:50-15:00. October 18 and 19, 2007 Session 1: Cell Death and Survival Chaired by Soichi Kojima (Saitama) and Hiroshi Matsumoto (Sapporo) Session 2: Oxidant Stress and Inflammation Chaired by Vishnudutt Purohit (NIAAA/NIH) and Katsuya Maruyama (Kurihama) Session 3: Metabolism, Cancer, and Genetics Chaired by Devanshi Seth (Sydney) and Akira Yokoyama (Kurihama) Session 4: Stellate Cell Biology and Fibrosis Chaired by Yuan-Ping Han (Los Angeles) and Norifumi Kawada (Osaka) DINNER October 19, 2007, 18:00~ JDDW joint buffet dinner (included with registration)

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