RfD Values by dns10434

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									CHEMICAL NAME                       RfD (mg/kg-d)             Target Organ                   Source   Revision Date                    Comments
Acenapththene                          6.0E-02                     liver                      IRIS
Acetone                                9.0E-01                    kidney                      IRIS
Alachlor                               1.0E-02                 circulatory                    IRIS
Aldicarb                               1.0E-03               AChe inhibition                  IRIS
Aldrin                                 3.0E-05                     liver                      IRIS
Anthracene                             3.0E-01                                                IRIS
Antimony                               4.0E-04                 circulatory                    IRIS
Arsenic                                3.0E-04                     skin                       IRIS
Atrazine                               3.5E-02         decreased body weight gain             IRIS
Barium                                 2.0E-01                    kidney                      IRIS
Benzene                                4.0E-03                 circulatory                    IRIS
Benzo(a)anthracene                       NA
Benzo(b)fluoranthene                     NA
Benzo(k)flouranthene                     NA
Benzo(a)pyrene                           NA
Benzoic Acid                          4.0E+00                                                 IRIS
Beryllium                              2.0E-03               gastrointestinal                 IRIS
Bis(2-chloroethyl)ether                  NA
Bis(2-ethylhexyl)phthalate             2.0E-02                     liver                      IRIS
Boron                                  2.0E-01                reproductive                    IRIS
Bromodichloromethane                   2.0E-02                    kidney                      IRIS
Bromoform                              2.0E-02                     liver                      IRIS
Butanol                                1.0E-01               nervous system                   IRIS
Butyl Benzyl Phthalate                 2.0E-01                     liver                      IRIS
Cadmium                                1.0E-03                    kidney                      IRIS                      RfD should be used for soil exposures only
Calcium                                  NA
Carbazole                                NA
Carbofuran                             5.0E-03    cholinesterase inhibition; reproductive     IRIS
Carbon disulfide                       1.0E-01                reproductive                    IRIS
Carbon Tetrachloride                   7.0E-04                     liver                      IRIS
Chlordane                              5.0E-04                     liver                      IRIS
Chloride                                 NA
4-Chloroaniline                        4.0E-03                    spleen                      IRIS
Chlorobenzene                          2.0E-02                     liver                      IRIS
Chlorodibromomethane                   2.0E-02                     liver                      IRIS
Chloroform                             1.0E-02                     liver                      IRIS
2-Chlorophenol                         5.0E-03                reproductive                    IRIS
Chromium (total)                                                                                                       Use toxicity values for Hexavalent Chromium
Chromium (trivalent ion)              1.5E+00                      NOAEL                      IRIS
Chromium (hexavalent ion)             3.0E-03                      NOAEL                      IRIS
Chrysene                                 NA
Cobalt                                3.0E-04                       thyroid                  PPRTV    10/6/2008 (CS)            replaces previous PPRTV
Copper                                4.0E-02                  gastrointestinal              HEAST
Cyanide                               2.0E-02      decr. body wt.; thyroid; nervous system    IRIS
2,4-D                                 1.0E-02                blood; liver; kidney             IRIS
Dalapon                               3.0E-02                       kidney                    IRIS
DDD                                      NA
DDE                                      NA
DDT                                   5.0E-04                        liver                    IRIS
Dibenzo(a,h)anthracene                   NA
1,2-dibromo-3-chloropropane           2.0E-04                   reproductive                 PPRTV    06/18/07 (MRR)
1,2-Dibromoethane                     9.0E-03            reproductive; liver; adrenal         IRIS
Di-n-butyl phthalate                  1.0E-01                increased mortality              IRIS
1,2-Dichlorobenzene                   9.0E-02                      NOAEL                      IRIS
1,4-Dichlorobenzene                   7.0E-02                       liver                    ATSDR    06/19/07 (MRR)
3,3'-Dichlorobenzidine                   NA
1,1-Dichloroethane                    2.0E-01                       kidney                   PPRTV    06/21/07 (MRR)
1,2-Dichloroethane                       NA
1,1-Dichloroethylene                  5.0E-02                           liver                 IRIS
cis-1,2-Dichloroethylene              1.0E-02                          blood                 PPRTV
trans-1,2-Dichloroethylene            2.0E-02                           liver                 IRIS
2,4-Dichlorophenol                    3.0E-03                  immune system                  IRIS
1,2-Dichloropropane                   9.0E-02                           liver                ATSDR    06/22/07 (MRR)
1,3-Dichloropropene (cis + trans)     3.0E-02          chronic irritation in forestomach      IRIS
Dieldrin                              5.0E-05                           liver                 IRIS
Diethyl phthalate                     8.0E-01                  decr. growth rate              IRIS
2,4-Dimethylphenol                    2.0E-02              nervous system; blood              IRIS
2,4-Dinitrophenol                     2.0E-03             cataract formation in eye           IRIS
2,4-Dinitrotoluene                    2.0E-03           nervous system; blood; liver          IRIS
2,6-Dinitrotoluene                    1.0E-03           nervous system; blood; liver         PPRTV    5/29/2007 (LM)
Dinoseb                               1.0E-03                       fetotoxicity              IRIS
Di-n-octyl phthalate                  4.0E-02                     liver; thyroid             PPRTV    5/29/2007 (LM)
Ensosulfan                            6.0E-03          body weight; kidney; circulatory       IRIS
Endothall                             2.0E-02                        digestive                IRIS
Endrin                                3.0E-04                       liver; CNS                IRIS
Ethylbenzene                          1.0E-01                     liver; kidney               IRIS
Fluoranthene                          4.0E-02                liver; kidney; blood             IRIS
Fluorene                              4.0E-02                          blood                  IRIS
Fluoride                              6.0E-02                        digestive                IRIS
Heptachlor                            5.0E-04                           liver                 IRIS
Heptachlor epoxide                    1.3E-05                           liver                 IRIS
Hexachlorobenzene                     8.0E-04                           liver                 IRIS
alpha-HCH (alpha-BHC)                 8.0E-03                           liver                ATSDR    5/31/2007 (LM)
gamma-HCH (gamma-BHC)                 3.0E-04                     liver; kidney               IRIS
Hexachlorocyclopentadiene             6.0E-03                        digestive                IRIS
Hexachloroethane                      1.0E-03                          kidney                 IRIS
Indeno(1,2,3-cd)pyrene                   NA
Iron                                  7.0E-01                     digestive                  PPRTV       2/5/2007
Isophorone                            2.0E-01                     NOAEL                       IRIS
Lead                                     NA                                                                                           contact TAU
Magnesium                                                      NA
Manganese                                                   2.0E-02                 CNS                   IRIS x 0.167     12/14/2000          corrected for non-food sources
Mercury                                                     3.0E-04               immune                      IRIS
Methoxychlor                                                5.0E-03             reproductive                  IRIS
Methyl bromide (bromomethane)                               1.4E-03               digestive                   IRIS
Methy tertiary-butyl ether                                  1.0E-02              liver; digestive             TAU                         TAU derived value to support GW standard
Methylene Chloride                                          6.0E-02                   liver                   IRIS
2-methylphenol (o-cresol)                                   5.0E-02         body weight; nervous              IRIS
Naphthalene                                                 2.0E-02             body weight                   IRIS
Nickel                                                      2.0E-02             body weight                   IRIS
Nitrate as N                                                1.6E+00                  blood                    IRIS
Nitrobenzene                                                5.0E-04      adrenal; liver; kidney; blood        IRIS
n-Nitrosodiphenylamine                                      2.0E-02          eye; dec. body wt.             PPRTV        6/18/2007(TVH)
n-Nitrosodi-n-propylamine                                      NA
Pentachlorophenol                                           3.0E-02             liver & kidney               IRIS
Phenol                                                      3.0E-01         dec. maternal wt. gain           IRIS
Phosphorus                                                                                                               8/1/2007(TVH)
Picloram                                                    7.0E-02                liver                     IRIS
Polychlorinated biphenyls (PCBs)                            2.0E-05       immunological; eyes;nails          IRIS
Potassium                                                      NA                                                        6/22/2007(TVH)
Pyrene                                                      3.0E-02               kidney                     IRIS
Selenium                                                    5.0E-03              selenosis                   IRIS
Silver                                                      5.0E-03               argyria                    IRIS
Simazine                                                    5.0E-03   decreased body weight gain; blood      IRIS
Sodium                                                         NA                                                        6/22/2007(TVH)
Sulfate                                                        NA                                                        6/22/2007(TVH)
Styrene                                                     2.0E-01         red blood cells; liver           IRIS
Tetrachloroethylene                                         1.0E-02   decreased body weight gain; liver      IRIS
Thallium                                                    8.0E-05               NOAEL                      IRIS
Toluene                                                     8.0E-02                kidney                    IRIS
Toxaphene                                                      NA
2,4,5-TP (Silvex)                                           8.0E-03                 liver                    IRIS
1,2,4-Trichlorobenzene                                      1.0E-02             adrenal gland                IRIS
1,1,1-Trichloroethane                                       2.0E+00              dec body wt                 IRIS        3/19/2008(LM)
1,1,2-Trichloroethane                                       4.0E-03                 liver                    IRIS
Trichloroethylene                                              NA                                                        7/2/2007(TVH)
2,4,5-Trichlorophenol                                       1.0E-01             liver & kidney               IRIS
2,4,6-Trichlorophenol                                       1.0E-03             dec. litter size            PPRTV        2/21/2008(TVH)
Vanadium                                                    7.0E-03                not given                HEAST
Vinyl acetate                                               1.0E+00          kidney; whole body             HEAST
Vinyl Choride                                               3.0E-03                   liver                  IRIS
Xylene                                                      2.0E-01       dec body wt; inc mortality         IRIS
m-xylene                                                    2.0E-01       dec body wt; inc mortality         IRIS
o-xylene                                                    2.0E-01       dec body wt; inc mortality         IRIS
p-xylene                                                    2.0E-01       dec body wt; inc mortality         IRIS
Zinc                                                        3.0E-01       blood chemistry changes            IRIS




                                                9/6/2010

NOTES:
IRIS: USEPA Integrated Risk Information System
HEAST: USEPA Health Effects Assessment Summary Tables
PPRTV: USEPA Provisional Peer Reviewed Toxicity Values
ATSDR: Agency for Toxic Substances and Disease Registry
RfD: Reference Dose
TAU: Illinois EPA Toxicity Assessment Unit (217-785-0830)
NOAEL: No Observed Adverse Effect Level
CHEMICAL NAME                       RfC (mg/m3)          Target Organ             Source    Revision Date                 RfDi (mg/kg-day)                            Comments
Acenapththene                            NA                                                                                      NA
Acetone                                  NA                                                                                      NA
Alachlor                                 NA                                                                                      NA
Aldicarb                                 NA                                                                                      NA
Aldrin                                   NA                                                                                      NA
Anthracene                               NA                                                                                      NA
Antimony                                 NA                                                                                      NA
Arsenic                               3.0E-05             reproductive            CAL EPA    5/30/07 (CS)                      8.6E-06
Atrazine                                 NA                                                                                      NA
Barium                                   NA                                                  5/30/07 (CS)                        NA
Benzene                               3.0E-02              circulatory             IRIS                                        8.6E-03
Benzo(a)anthracene                       NA                                                                                      NA
Benzo(b)fluoranthene                     NA                                                                                      NA
Benzo(k)flouranthene                     NA                                                                                      NA
Benzo(a)pyrene                           NA                                                                                      NA
Benzoic Acid                             NA                                                                                      NA
Beryllium                             2.0E-05              respiratory             IRIS                      internal   dose conversion inappropriate
Bis(2-chloroethyl)ether                  NA                                                                                      NA
Bis(2-ethylhexyl)phthalate              NA                                                                                       NA
Boron                                   NA                                                   5/31/07 (CS)                        NA
Bromodichloromethane                    NA                                                                                       NA
Bromoform                               NA                                                                                       NA
Butanol                                 NA                                                                                       NA
Butyl Benzyl Phthalate                  NA                                                                                       NA
Cadmium                               2.0E-05         kidney; respiratory         CAL EPA    6/4/07 (CS)                       5.7E-06
Calcium                                 NA                                                                                       NA
Carbazole                               NA                                                                                       NA
Carbofuran                              NA                                                                                       NA
Carbon disulfide                      7.0E-01           nervous system              IRIS                                       2.0E-01
Carbon Tetrachloride                  4.0E-02                liver                CAL EPA    6/1/07 (CS)                       1.1E-02
Chlordane                             7.0E-04                liver                  IRIS     6/1/07 (CS)                       2.0E-04
Chloride                                NA                                                                                       NA
4-Chloroaniline                         NA                                                                                       NA
Chlorobenzene                         5.0E-02                kidney               PPRTV      6/1/07 (CS)                       1.4E-02
Chlorodibromomethane                    NA                                                                                       NA
Chloroform                            1.0E-01                 liver               ATSDR     06/15/07 (MRR)                     2.9E-02
2-Chlorophenol                          NA                                                                                       NA
Chromium (total)                                                                                                                                     Use toxicity values for hexavalent chromium
Chromium (trivalent ion)                 NA                                                                                      NA
Chromium (hexavalent ion)             1.0E-04              respiratory             IRIS                      internal   dose conversion inappropriate
Chrysene                                 NA                                                                                      NA
Cobalt                                6.0E-06              respiratory            PPRTV      10/6/08 (CS)    internal   dose conversion inappropriate       replaces the previous PPRTV
Copper                                   NA                                                                                      NA
Cyanide                                  NA                                                                                      NA
2,4-D                                    NA                                                                                      NA
Dalapon                                  NA                                                                                      NA
DDD                                      NA                                                                                      NA
DDE                                      NA                                                                                      NA
DDT                                      NA                                                                                      NA
Dibenzo(a,h)anthracene                   NA                                                                                      NA
1,2-dibromo-3-chloropropane           2.0E-04             reproductive             IRIS                                        5.7E-05
1,2-Dibromoethane                     9.0E-03              respiratory             IRIS                      internal   dose conversion inappropriate
Di-n-butyl phthalate                     NA                                                                                      NA
1,2-Dichlorobenzene                   2.0E-01       decreased body weight         HEAST                                        5.7E-02
1,4-Dichlorobenzene                   8.0E-01               liver                  IRIS                                        2.3E-01
3,3'-Dichlorobenzidine                   NA                                                                                      NA
1,1-Dichloroethane                    5.0E-01                kidney               HEAST                                        1.4E-01
1,2-Dichloroethane                    2.4E+00                 liver               ATSDR     06/21/07 (MRR)                     6.9E-01
1,1-Dichloroethylene                  2.0E-01                 liver                IRIS                                        5.7E-02
cis-1,2-Dichloroethylene                 NA                                                                                      NA
trans-1,2-Dichloroethylene            6.0E-02           liver; respiratory        PPRTV     06/21/07 (MRR)                     1.7E-02
2,4-Dichlorophenol                       NA                                                                                      NA
1,2-Dichloropropane                   4.0E-03              respiratory             IRIS                      internal   dose conversion inappropriate
1,3-Dichloropropene (cis + trans)     2.0E-02              respiratory             IRIS                      internal   dose conversion inappropriate
Dieldrin                                 NA                                                                                      NA
Diethyl phthalate                        NA                                                                                      NA
2,4-Dimethylphenol                       NA                                                                                      NA
2,4-Dinitrophenol                        NA                                                                                      NA
2,4-Dinitrotoluene                       NA                                                                                      NA
2,6-Dinitrotoluene                       NA                                                                                      NA
Dinoseb                                  NA                                                                                      NA
Di-n-octyl phthalate                     NA                                                                                      NA
Ensosulfan                               NA                                                                                      NA
Endothall                                NA                                                                                      NA
Endrin                                   NA                                                                                      NA
Ethylbenzene                          1.0E+00           developmental              IRIS                                        2.9E-01
Fluoranthene                             NA                                                                                      NA
Fluorene                                 NA                                                                                      NA
Fluoride                                 NA                                                                                      NA
Heptachlor                               NA                                                                                      NA
Heptachlor epoxide                       NA                                                                                      NA
Hexachlorobenzene                        NA                                                                                      NA
alpha-HCH (alpha-BHC)                    NA                                                                                      NA
gamma-HCH (gamma-BHC)                    NA                                                                                      NA
Hexachlorocyclopentadiene             2.0E-04              respiratory             IRIS                      internal   dose conversion inappropriate
Hexachloroethane                         NA                                                                                      NA
Indeno(1,2,3-cd)pyrene                   NA                                                                                      NA
Iron                                     NA                                                                                      NA
Isophorone                            2.0E+00        developmental; liver         CalEPA    6/5/2007 (LM)                      5.7E-01
Lead                                     NA                                                                                      NA
Magnesium                                NA                                                                                      NA
Manganese                             5.0E-05           nervous system             IRIS                                        1.4E-05
Mercury                               3.0E-04           nervous system             IRIS                                        8.6E-05
Methoxychlor                             NA                                                                                      NA
Methyl bromide (bromomethane)         5.0E-03             respiratory              IRIS                      internal   dose conversion inappropriate
Methy tertiary-butyl ether            3.0E+00            liver; kidney             IRIS                                        8.6E-01
Methylene Chloride                    4.0E-01              circulatory            CalEPA    6/6/2007 (LM)                      1.1E-01
2-Methylphenol (o-cresol)             6.0E-01        body weight; nervous         CalEPA    6/6/2007 (LM)                      1.7E-01
Naphthalene                           3.0E-03             respiratory              IRIS                      internal   dose conversion inappropriate
Nickel                                5.0E-05       respiratory; circulatory      CalEPA    6/6/2007 (LM)    internal   dose conversion inappropriate
Nitrate as N                             NA                                                                                      NA
Nitrobenzene                          2.0E-03     adrenal; liver; kidney; blood   HEAST                                        5.7E-04
n-Nitrosodiphenylamine                                         NA                                                                      NA
n-Nitrosodi-n-propylamine                                      NA                                                                      NA
Pentachlorophenol                                              NA                                                                      NA
Phenol                                                      2.0E-01     nervous system       CalEPA   6/18/2007(TVH) internal dose conversion inappropriate
Phosphorus                                                     NA                                                                      NA
Picloram                                                       NA                                                                      NA
Polychlorinated biphenyls (PCBs)                               NA                                                                      NA
Potassium                                                      NA                                     6/22/2007(TVH)                   NA
Pyrene                                                         NA                                                                      NA
Selenium                                                       NA                                                                      NA
Silver                                                         NA                                                                      NA
 Simazine                                                      NA                                                                      NA
Sodium                                                         NA                                     6/22/2770(TVH)                   NA
Sulfate                                                        NA                                     6/22/2007(TVH)                   NA
Styrene                                                     1.0E+00          CNS              IRIS                                  2.9E-01
Tetrachloroethylene                                         2.7E-01       neurological       ATSDR    6/22/2007(TVH)                7.7E-02
Thallium                                                       NA                                                                      NA
Toluene                                                     5.0E+00          CNS              IRIS                                  1.4E+00
Toxaphene                                                      NA                                                                      NA
2,4,5-TP (Silvex)                                              NA                                                                      NA
1,2,4-Trichlorobenzene                                      4.0E-03           liver          PPRTV     7/2/2007(TVH)                1.1E-03
1,1,1-Trichloroethane                                       5.0E+00           liver           IRIS    10/4/2007(TVH)                1.4E+00
1,1,2-Trichloroethane                                          NA                                                                      NA
Trichloroethylene                                           6.0E-01   nervous system; eyes   CalEPA    7/2/2007(TVH)                1.7E-01
2,4,5-Trichlorophenol                                          NA                                                                      NA
2,4,6-Trichlorophenol                                          NA                                                                      NA
Vanadium                                                       NA                                                                      NA
Vinyl acetate                                               2.0E-01          nasal            IRIS                   internal dose conversion inappropriate
Vinyl Choride                                               1.0E-01          liver            IRIS                                  2.9E-02
Xylene                                                      1.0E-01           CNS             IRIS                                  2.9E-02
m-xylene                                                    1.0E-01           CNS             IRIS                                  2.9E-02
o-xylene                                                    1.0E-01           CNS             IRIS                                  2.9E-02
p-xylene                                                    1.0E-01           CNS             IRIS                                  2.9E-02
Zinc                                                           NA                                                                      NA




                                                9/6/2010

NOTES:
IRIS: USEPA Integrated Risk Information System
HEAST: USEPA Health Effects Assessment Summary Tables
PPRTV: USEPA Provisional Peer Reviewed Toxicity Values
ATSDR: Agency for Toxic Substances and Disease Registry
TAU: Illinois EPA Toxicity Assessment Unit (217-785-0830)
CalEPA: California EPA
RfC: Reference Concentration
RfDi: Inhalation Reference Dose
CHEMICAL NAME                       RfDs (mg/kg-d)               Target Organ                  Source     Revision Date                   Comments
Acenapththene                          6.0E-01                         liver                   IRIS/UF
Acetone                                3.0E+00                       kidney                    IRIS/UF    5/24/07 (CS)
Alachlor                               1.0E-02                     circulatory                 HEAST
Aldicarb                               1.0E-03                   AChe inhibition               HEAST
Aldrin                                 4.0E-05                       kidney                    PPRTV      5/31/07 (CS)
Anthracene                             3.0E+00                                                 IRIS/UF
Antimony                               4.0E-04                    circulatory                  PPRTV      10/23/08(CS)
Arsenic                                3.0E-04                        skin                     HEAST
Atrazine                               3.5E-02            decreased body weight gain           HEAST
Barium                                 7.0E-01                      kidney                     ATSDR      5/30/07 (CS)
Benzene                                1.2E-02                    circulatory                  IRIS/UF    5/31/07 (CS)
Benzo(a)anthracene                        NA
Benzo(b)fluoranthene                      NA
Benzo(k)flouranthene                      NA
Benzo(a)pyrene                            NA
Benzoic Acid                           4.0E+00                                                 PPRTV      5/31/07 (CS)
Beryllium                              2.0E-03                   gastrointestinal               IRIS                              chronic value used as default
Bis(2-chloroethyl)ether                   NA
Bis(2-ethylhexyl)phthalate             1.0E-01                   reproductive                  ATSDR      5/31/07 (CS)
Boron                                  2.0E-01                   reproductive                    IRIS                             chronic value used as default
Bromodichloromethane                   2.0E-02                      kidney                     HEAST
Bromoform                              3.0E-02                       liver                     PPRTV      5/31/07 (CS)
Butanol                                1.0E+00                  nervous system                 IRIS/UF    5/31/07 (CS)
Butyl Benzyl Phthalate                 2.0E+00                       liver                     IRIS/UF    5/31/07 (CS)
Cadmium                                1.0E-03                      kidney                       IRIS                             chronic value used as default
Calcium                                   NA
Carbazole                                 NA
Carbofuran                             5.0E-03       cholinesterase inhibition; reproductive   HEAST
Carbon disulfide                       1.0E-01                   reproductive                  HEAST
Carbon Tetrachloride                   7.0E-03                        liver                    IRIS/UF     6/1/07 (CS)
Chlordane                              6.0E-04                        liver                    ATSDR       6/1/07 (CS)
Chloride                                  NA
4-Chloroaniline                        4.0E-03                       spleen                    HEAST
Chlorobenzene                          7.0E-02                    liver; kidney                PPRTV       6/1/07 (CS)
Chlorodibromomethane                   2.0E-01                         liver                   IRIS/UF
Chloroform                             1.0E-01                         liver                   ATSDR       3/3/2008 (LM)
2-Chlorophenol                         8.0E-03                    reproductive                 PPRTV     2/22/2008 (MRR)
Chromium (total)                                                                                                           use toxicity values for hexavalent chromium
Chromium (trivalent ion)               1.5E+00                      NOAEL                        IRIS                             chronic value used as default
Chromium (hexavalent ion)              8.0E-03                      NOAEL                      IRIS/UF   01/14/08 (MRR)
Chrysene                                  NA
Cobalt                                 3.0E-03                        thyroid                  PPRTV      10/6/08 (CS)           replaces previous PPRTV/UF
Copper                                 4.0E-02                   gastrointestinal              HEAST                             chronic value used as default
Cyanide                                2.0E-02       decr. body wt.; thyroid; nervous system   HEAST
2,4-D                                  1.0E-02                 blood; liver; kidney            HEAST
Dalapon                                3.0E-02                        kidney                   HEAST
DDD                                       NA
DDE                                       NA
DDT                                    5.0E-04                        liver                    ATSDR
Dibenzo(a,h)anthracene                    NA
1,2-dibromo-3-chloropropane            2.0E-03                    reproductive                 PPRTV     06/18/07 (MRR)
1,2-Dibromoethane                      9.0E-03             reproductive; liver; adrenal          IRIS                             chronic value used as default
Di-n-butyl phthalate                   1.0E+00                 increased mortality             IRIS/UF
1,2-Dichlorobenzene                    6.0E-01                        liver                    ATSDR     06/19/07 (MRR)
1,4-Dichlorobenzene                    7.0E-02                        liver                    ATSDR     06/21/07 (MRR)
3,3'-Dichlorobenzidine                    NA
1,1-Dichloroethane                     2.0E+00                         kidney                  PPRTV     06/21/07 (MRR)
1,2-Dichloroethane                     2.0E-01                         kidney                  ATSDR     06/21/07 (MRR)
1,1-Dichloroethylene                   5.0E-02                           liver                   IRIS                             chronic value used as default
cis-1,2-Dichloroethylene               1.0E-01                          blood                  PPRTV
trans-1,2-Dichloroethylene             2.0E-01                           liver                 IRIS/UF
2,4-Dichlorophenol                     3.0E-03                   immune system                 HEAST     06/22/07 (MRR)
1,2-Dichloropropane                    9.0E-02                           liver                 ATSDR     06/22/07 (MRR)           chronic value used as default
1,3-Dichloropropene (cis + trans)      4.0E-02                    gastrointestinal             ATSDR     06/22/07 (MRR)
Dieldrin                               1.0E-04                     neurological                ATSDR     06/22/07 (MRR)
Diethyl phthalate                      8.0E+00                   decr. growth rate               IRIS
2,4-Dimethylphenol                     5.0E-02              nervous system; blood              PPRTV     02/22/08 (MRR)
2,4-Dinitrophenol                      2.0E-02             cataract formation in eye           PPRTV     02/22/08 (MRR)
2,4-Dinitrotoluene                     2.0E-03                nervous; blood; liver              IRIS
2,6-Dinitrotoluene                     1.0E-02                nervous; blood; liver            PPRTV
Dinoseb                                1.0E-03                       fetotoxicity                IRIS
Di-n-octyl phthalate                   4.0E-01                     liver; thyroid              PPRTV     5/29/2007 (LM)
Ensosulfan                             6.0E-03          body weight; kidney; circulatory         IRIS
Endothall                              2.0E-02                   digestive system                IRIS
Endrin                                 3.0E-04               liver; nervous system             HEAST
Ethylbenzene                           1.0E-01                      liver; kidney              PPRTV     5/30/2007 (LM)
Fluoranthene                           4.0E-01                 liver; kidney; blood            IRIS/UF
Fluorene                               4.0E-01                          blood                  IRIS/UF
Fluoride                               6.0E-02                   digestive system                IRIS
Heptachlor                             5.0E-04                           liver                   IRIS
Heptachlor epoxide                     1.3E-05                           liver                 HEAST
Hexachlorobenzene                      8.0E-04                           liver                   IRIS
alpha-HCH (alpha-BHC)                  8.0E-03                           liver                 ATSDR     5/31/2007 (LM)
gamma-HCH (gamma-BHC)                  3.0E-03                      liver; kidney                IRIS
Hexachlorocyclopentadiene              2.0E-02                   digestive system              IRIS/UF    6/4/2007 (LM)
Hexachloroethane                       1.0E-02                         kidney                  IRIS/UF
Indeno(1,2,3-cd)pyrene                    NA
Iron                                   7.0E-01                  digestive system               PPRTV
Isophorone                             2.0E+00                      NOAEL                       IRIS
Lead                                      NA                                                                                              Contact TAU
Magnesium                                                      NA
Manganese                                                   2.0E-02             nervous system              IRIS
Mercury                                                     3.0E-03             immune system             IRIS/UF    6/5/2007 (LM)
Methoxychlor                                                5.0E-03          reproductive system          ATSDR
Methyl bromide (bromomethane)                               5.0E-03            digestive system           PPRTV
Methy tertiary-butyl ether                                  1.0E-01        liver; digestive system        TAU/UF     6/6/2007 (LM)
Methylene Chloride                                          6.0E-02                   liver               HEAST
2-Methylphenol (o-cresol)                                   5.0E-01     body weight; nervous system       IRIS/UF
Naphthalene                                                 2.0E-01               body weight             IRIS/UF    6/6/2007 (LM)
Nickel                                                      2.0E-02               body weight             HEAST
Nitrate as N                                                1.6E+00                  blood                  IRIS
Nitrobenzene                                                5.0E-03      adrenal; liver; kidney; blood    IRIS/UF
n-Nitrosodiphenylamine                                      2.0E-02            eye; dec. body wt          PPRTV      6/18/2007(TVH)            chronic value used as default
n-Nitrosodi-n-propylamine                                      NA
Pentachlorophenol                                           3.0E-02              liver; kidney              IRIS                               ATSDR<chronic; used chronic
Phenol                                                      3.0E-01         dec. maternal wt. gain          IRIS                               chronic value used as default
Phosphorus                                                     NA                                                    8/1/2007(TVH)
Picloram                                                    7.0E-02                liver                    IRIS                               chronic value used as default
Polychlorinated biphenyls (PCBs)                            5.0E-05       eye; immunological; nails        IRIS/3    1/9/2008(TVH)    derived using Arochlor 1254 LOAEL & UF = 100
Potassium                                                      NA                                                    6/22/2007(TVH)
Pyrene                                                      3.0E-01               kidney                   PPRTV     2/21/2008(TVH)
Selenium                                                    5.0E-03              selenosis                  IRIS                               chronic value used as default
Silver                                                      5.0E-03               argyria                  HEAST
Simazine                                                    5.0E-03   decreased body weight gain; blood    HEAST
Sodium                                                         NA                                                    6/22/2007(TVH)
Sulfate                                                        NA                                                    6/22/2007(TVH)
Styrene                                                     2.0E+00         red blood cells; liver         IRIS/10   6/22/2007(TVH)
Tetrachloroethylene                                         1.0E-01   decreased body weight gain; liver    IRIS/10   6/22/2007(TVH)
Thallium                                                    8.0E-04               NOAEL                    IRIS/10
Toluene                                                     8.0E-01                kidney                  IRIS/10
Toxaphene                                                   1.0E-03                 liver                  ATSDR     7/2/2007(TVH)
2,4,5-TP (Silvex)                                           8.0E-03                 liver                    IRIS                     chronic value used as default (corrected 3/19/08)
1,2,4-Trichlorobenzene                                      1.0E-02               adrenal                  HEAST
1,1,1-Trichloroethane                                       7.0E+00        decreased body weight             IRIS    7/2/2007(TVH)               (updated 3/19/08 LM)
1,1,2-Trichloroethane                                       4.0E-03                 liver                    IRIS    8/28/2007(TVH)           PPRTV < chronic; used chronic
Trichloroethylene                                              NA                                                    7/2/2007(TVH)
2,4,5-Trichlorophenol                                       3.0E-01            liver & kidney              PPRTV     2/21/2008(TVH)
2,4,6-Trichlorophenol                                       1.0E-02         decreased litter size         PPRTV/10      2/21/2008
Vanadium                                                    7.0E-03               not given                HEAST                                   ATSDR value<chronic
Vinyl acetate                                               1.0E+00         whole body; kidney             HEAST
Vinyl Choride                                               3.0E-03                  liver                  IRIS                               chronic value used as default
Xylene                                                      1.0E+00                 CNS                    ATSDR     6/18/2007(TVH)
m-xylene                                                    1.0E+00                 CNS                    ATSDR     6/18/2007(TVH)
o-xylene                                                    1.0E+00                 CNS                    ATSDR     6/18/2007(TVH)
p-xylene                                                    1.0E+00                 CNS                    ATSDR     6/18/2007(TVH)
Zinc                                                        3.0E-01                 blood                  HEAST




                                                9/6/2010

NOTES:
IRIS: USEPA Integrated Risk Information System
HEAST: USEPA Health Effects Assessment Summary Tables
PPRTV: USEPA Provisional Peer Reviewed Toxicity Values
ATSDR: Agency for Toxic Substances and Disease Registry
RfD: Reference Dose
TAU: Illinois EPA Toxicity Assessment Unit (217-785-0830)
CalEPA: California EPA
UF: Uncertainty Factor
RfDs: Subchronic Reference Dose
CHEMICAL NAME                       RfCs (mg/m3)          Target Organ              Source     Revision Date                RfDis(mg/kg-d)                            Comments
Acenapththene                            NA                                                                                       NA
Acetone                                  NA                                                                                       NA
Alachlor                                 NA                                                                                       NA
Aldicarb                                 NA                                                                                       NA
Aldrin                                   NA                                                                                       NA
Anthracene                               NA                                                                                       NA
Antimony                               4.0E-04             respiratory              PPRTV       5/31/07 (CS)    internal dose conversion inappropriate
Arsenic                                3.0E-05             reprodutive             CAL EPA      5/30/07 (CS)                   8.6E-06
Atrazine                                 NA                                                                                       NA
Barium                                   NA                                                     5/30/07 (CS)                      NA
Benzene                                8.0E-02              circulatory             IRIS/UF     5/31/07 (CS)                   2.3E-02
Benzo(a)anthracene                       NA                                                                                       NA
Benzo(b)fluoranthene                     NA                                                                                       NA
Benzo(k)flouranthene                     NA                                                                                       NA
Benzo(a)pyrene                           NA                                                                                       NA
Benzoic Acid                           2.0E-03            respiratory               PPRTV       5/31/07 (CS)    internal dose conversion inappropriate
Beryllium                              2.0E-05            respiratory                IRIS                       internal dose conversion inappropriate       chronic value used as default
Bis(2-chloroethyl)ether                1.2E-01       decreased body weight          ATSDR       5/31/07 (CS)                   3.4E-02
Bis(2-ethylhexyl)phthalate               NA                                                                                       NA
Boron                                    NA                                                     5/31/07 (CS)                      NA
Bromodichloromethane                     NA                                                                                       NA
Bromoform                                NA                                                                                       NA
Butanol                                  NA                                                                                       NA
Butyl Benzyl Phthalate                   NA                                                                                       NA
Cadmium                                5.0E-05         kidney; respiratory         CAL EPA       6/4/07 (CS)                   1.4E-05
Calcium                                  NA                                                                                       NA
Carbazole                                NA                                                                                       NA
Carbofuran                               NA                                                                                       NA
Carbon disulfide                      2.0E+00            nervous system             IRIS/UF     5/31/07 (CS)                   5.7E-01
Carbon Tetrachloride                   1.9E-01                liver                 ATSDR       6/01/07 (CS)                   5.4E-02
Chlordane                              7.0E-03                liver                 IRIS/UF     6/01/07 (CS)                   2.0E-03
Chloride                                 NA                                                                                       NA
4-Chloroaniline                          NA                                                                                       NA
Chlorobenzene                          5.0E-01                kidney                PPRTV       6/01/07 (CS)                   1.4E-01
Chlorodibromomethane                     NA                                                                                       NA
Chloroform                             2.4E-01                 liver                ATSDR      06/15/07 (MRR)                  6.9E-02
2-Chlorophenol                           NA                                                                                       NA
Chromium (total)                                                                                                                                       use toxicity values for hexavalent chromium
Chromium (trivalent ion)                 NA                                                                                       NA
Chromium (hexavalent ion)             1.0E-03              respiratory              IRIS/UF    06/15/07 (MRR)   internal dose conversion inappropriate
Chrysene                                 NA                                                                                       NA
Cobalt                                2.0E-05              respiratory              PPRTV       10/6/08 (CS)    internal dose conversion inappropriate        replaces the previous PPRTV
Copper                                   NA                                                                                       NA
Cyanide                                  NA                                                                                       NA
2,4-D                                    NA                                                                                       NA
Dalapon                                  NA                                                                                       NA
DDD                                      NA                                                                                       NA
DDE                                      NA                                                                                       NA
DDT                                      NA                                                                                       NA
Dibenzo(a,h)anthracene                   NA                                                                                       NA
1,2-dibromo-3-chloropropane           2.0E-03             reproductive              IRIS/UF    06/18/07(MRR)                   5.7E-04
1,2-Dibromoethane                     9.0E-03              respiratory                IRIS                      internal dose conversion inappropriate        chronic value used as default
Di-n-butyl phthalate                     NA                                                                                       NA
1,2-Dichlorobenzene                   2.0E+00        decreased body weight          HEAST                                      5.7E-01
1,4-Dichlorobenzene                   2.0E+00                liver                  IRIS/UF    01/14/08 (MRR)                  5.7E-01
3,3'-Dichlorobenzidine                   NA                                                                                       NA
1,1-Dichloroethane                    5.0E+00                 kidney                HEAST                                      1.4E+00
1,2-Dichloroethane                    2.4E+00                  liver                ATSDR      06/21/07 (MRR)                  6.9E-01                        chronic value used as default
1,1-Dichloroethylene                  2.0E-01                  liver                 IRIS                                      5.7E-02                        chronic value used as default
cis-1,2-Dichloroethylene                 NA                                                                                       NA
trans-1,2-Dichloroethylene            6.0E-01            liver; respiratory         PPRTV      06/21/07 (MRR)   internal dose conversion inappropriate
2,4-Dichlorophenol                       NA                                                                                       NA
1,2-Dichloropropane                   1.0E-02              respiratory              IRIS/UF    01/14/08 (MRR)   internal dose conversion inappropriate
1,3-Dichloropropene (cis + trans)     4.0E-02              respiratory              ATSDR      06/22/07 (MRR)   internal dose conversion inappropriate
Dieldrin                                 NA                                                                                       NA
Diethyl phthalate                        NA                                                                                       NA
2,4-Dimethylphenol                       NA                                                                                       NA
2,4-Dinitrophenol                        NA                                                                                       NA
2,4-Dinitrotoluene                       NA                                                                                       NA
2,6-Dinitrotoluene                       NA                                                                                       NA
Dinoseb                                  NA                                                                                       NA
Di-n-octyl phthalate                     NA                                                                                       NA
Ensosulfan                               NA                                                                                       NA
Endothall                                NA                                                                                       NA
Endrin                                   NA                                                                                       NA
Ethylbenzene                          1.0E+00            developmental              PPRTV      5/30/2007 (LM)                  2.9E-01
Fluoranthene                             NA                                                                                       NA
Fluorene                                 NA                                                                                       NA
Fluoride                                 NA                                                                                       NA
Heptachlor                               NA                                                                                       NA
Heptachlor epoxide                       NA                                                                                       NA
Hexachlorobenzene                        NA                                                                                       NA
alpha-HCH (alpha-BHC)                    NA                                                                                       NA
gamma-HCH (gamma-BHC)                    NA                                                                                       NA
Hexachlorocyclopentadiene             1.0E-01              respiratory              ATSDR      6/4/2007 (LM)    internal dose conversion inappropriate
Hexachloroethane                      6.0E+01            nervous system             ATSDR      6/4/2007 (LM)                   1.7E+01
Indeno(1,2,3-cd)pyrene                   NA                                                                                       NA
Iron                                     NA                                                                                       NA
Isophorone                            2.0E+00          developmental; liver         CalEPA     6/5/2007 (LM)                   5.7E-01
Lead                                     NA                                                                                       NA
Magnesium                                NA                                                                                       NA
Manganese                             5.0E-05            nervous system              IRIS                                      1.4E-05                  Chronic RfC used w/o modif. per USEPA
Mercury                               3.0E-04            nervous system              IRIS                                      8.6E-05
Methoxychlor                             NA                                                                                       NA
Methyl bromide (bromomethane)         1.0E-01           respiratory system          PPRTV      6/6/2007 (LM)    internal dose conversion inappropriate
Methy tertiary-butyl ether            3.0E+00              liver; kidney              IRIS                                     8.6E-01
Methylene Chloride                    4.0E-01               circulatory             CalEPA     6/6/2007 (LM)                   1.1E-01
2-Methylphenol (o-cresol)             1.8E+00      body weight; nervous system     CalEPA/UF   6/6/2007 (LM)                   5.1E-01
Naphthalene                           3.0E-03               respiratory               IRIS                      internal dose conversion inappropriate
Nickel                                2.0E-04               respiratory             ATSDR      6/6/2007 (LM)    internal dose conversion inappropriate
Nitrate as N                             NA                                                                                       NA
Nitrobenzene                          2.0E-02      adrenal; liver; kidney; blood    HEAST                                      5.7E-03
n-Nitrosodiphenylamine                   NA                                                                                       NA
n-Nitrosodi-n-propylamine                NA                                                                                       NA
Pentachlorophenol                        NA                                                                                       NA
Phenol                                6.0E-01         liver; nervous system        CalEPA/3    6/18/2007(TVH)                  1.7E-01
Phosphorus                                                     NA                                                                           NA
Picloram                                                       NA                                                                           NA
Polychlorinated biphenyls (PCBs)                               NA                                                                           NA
Potassium                                                      NA                                       6/22/2007(TVH)                      NA
Pyrene                                                         NA                                                                           NA
Selenium                                                       NA                                                                           NA
Silver                                                         NA                                                                           NA
Simazine                                                       NA                                                                           NA
Sodium                                                         NA                                       6/22/2007(TVH)                      NA
Sulfate                                                        NA                                       6/22/2007(TVH)                      NA
Styrene                                                     3.0E+00          CNS               IRIS/3   1/10/2008 (TVH)                  8.6E-01                    derived using NOAEL & UF = 10
Tetrachloroethylene                                         2.7E-01       neorological        ATSDR     6/22/2007(TVH)                   7.7E-02                     chronic value used as default
Thallium                                                       NA                                                                           NA
Toluene                                                     5.0E+00          CNS               IRIS                                      1.4E+00                     chronic value used as default
Toxaphene                                                      NA                                                                           NA
2,4,5-TP (Silvex)                                              NA                                                                           NA
1,2,4-Trichlorobenzene                                      4.0E-02           liver          PPRTV/10    7/2/2007(TVH)                   1.1E-02
1,1,1-Trichloroethane                                       5.0E+00           liver            IRIS     10/4/2007(TVH)                   1.4E+00
1,1,2-Trichloroethane                                          NA                                                                           NA
Trichloroethylene                                           6.0E-01   nervous system; eyes    CalEPA    8/28/2007(TVH)                   1.7E-01                 ATSDR<chronic; chronic used as default
2,4,5-Trichlorophenol                                          NA                                                                           NA
2,4,6-Trichlorophenol                                          NA                                                                           NA
Vanadium                                                       NA                                                                           NA
Vinyl acetate                                               2.0E-01          nasal            HEAST                       internal dose conversion inappropriate
Vinyl Choride                                               1.0E-01           liver            IRIS                                      2.9E-02                 ATSDR<chronic; chronic used as default
Xylene                                                      4.0E-01          CNS              IRIS/3    1/9/2008(TVH)                    1.1E-01                   derived using NOAEL & UF = 100
m-xylene                                                    4.0E-01          CNS              IRIS/3    1/9/2008(TVH)                    1.1E-01                   derived using NOAEL & UF = 100
o-xylene                                                    4.0E-01          CNS              IRIS/3    1/9/2008(TVH)                    1.1E-01                   derived using NOAEL & UF = 100
p-xylene                                                    4.0E-01          CNS              IRIS/3    1/9/2008(TVH)                    1.1E-01                   derived using NOAEL & UF = 100
Zinc                                                           NA                                                                           NA



                                                9/6/2010

NOTES:
IRIS: USEPA Integrated Risk Information System
HEAST: USEPA Health Effects Assessment Summary Tables
PPRTV: USEPA Provisional Peer Reviewed Toxicity Values
ATSDR: Agency for Toxic Substances and Disease Registry
RfD: Reference Dose
TAU: Illinois EPA Toxicity Assessment Unit (217-785-0830)
CalEPA: California EPA
UF: Uncertainty Factor
RfCs: Subchronic Reference Concentration
RfDis: Subchronic Inhalation Reference Dose
NOAEL: No Observaed Adverse Effect Level
CHEMICAL NAME                                               SFo (mg/kg-d)-1   Target Organ    Source   URF (ug/m3)-1   Target Organ   Source    Revision Date   SFi (mg/kg-d)-1   Comments
Tetrachloroethylene                                             5.4E-01           liver      CAL EPA     5.9E-06           liver      CalEPA   6/22/2007(TVH)       2.1E-02
Thallium                                                          NA                                        NA                                                         NA
Toluene                                                           NA                                        NA                                                         NA
Toxaphene                                                      1.1E+00            liver       IRIS       3.2E-04           liver       IRIS                         1.1E+00
2,4,5-TP (Silvex)                                                 NA                                        NA                                                         NA
1,2,4-Trichlorobenzene                                            NA                                        NA                                 7/2/2007(TVH)           NA
1,1,1-Trichloroethane                                             NA                                        NA                                                         NA
1,1,2-Trichloroethane                                             NA                                        NA                                                         NA
Trichloroethylene                                               1.3E-02        liver; lung   CAL EPA     2.0E-06        liver; lung   CalEPA   7/25/2007(TVH)       7.0E-03
2,4,5-Trichlorophenol                                             NA                                        NA                                                         NA
2,4,6-Trichlorophenol                                           1.1E-02         leukemia      IRIS       3.1E-06         leukemia      IRIS                         1.1E-02
Vanadium                                                          NA                                        NA                                                         NA
Vinyl acetate                                                     NA                                        NA                                                         NA
Vinyl Choride (Non-Residential)                                 7.2E-01           liver       IRIS       4.4E-06           liver       IRIS                         1.5E-02
Vinyl Choride (Residential)                                    1.5E+00            liver       IRIS       8.8E-06           liver       IRIS                         3.1E-02
Xylene                                                            NA                                        NA                                                         NA
m-xylene                                                          NA                                        NA                                                         NA
o-xylene                                                          NA                                        NA                                                         NA
p-xylene                                                          NA                                        NA                                                         NA
Zinc                                                              NA                                        NA                                                         NA




                                                 9/6/2010

NOTES:
IRIS: USEPA Integrated Risk Information System
HEAST: USEPA Health Effects Assessment Summary Tables
PPRTV: USEPA Provisional Peer Reviewed Toxicity Values
ATSDR: Agency for Toxic Substances and Disease Registry
TAU: Illinois EPA Toxicity Assessment Unit (217-785-0830)
CalEPA: California EPA
SFo: Oral Cancer Slope Factor
URF: Unit Risk Factor
SFi: Inhalation Slope Factor
RPF: Relative Potency Factors

								
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