Program Evaluation Report External Dosimetry Target Organ for Prostate Cancer - Program Evaluation Reports (PERs) and Program Evaluation Plans (PEPs)

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Document Number: Office of Compensation Analysis and Support OCAS-PER-006 Effective Date: Program Evaluation Report 09/15/2006 Revision No. 0 External dosimetry target organ for prostate cancer Date: 9/15/2006 Page 1 of 3 Supersedes: None Approval: Signature on File J.W. Neton, Associate Director for Science ISSUE AUTHORIZATION DATE 09/15/2006 EFFECTIVE DATE 09/15/2006 REV. NO. 0 DESCRIPTION New document to change external dosimetry target organ for prostate cancer from testes to bladder. 1.0 Description In May, 2004, OCAS determined that the urinary bladder was the appropriate surrogate external dosimetry target organ for the prostate gland. This superseded OCAS’ prior guidance1 that the testes should be used as the target organ. This decision was based primarily on the location of the prostate gland relative to the testes and the bladder (Figure 1). Figure 1: Location of the prostate gland relative to the urinary bladder and testes As seen in Figure 1, the testes lie very close to the skin surface, and therefore receive shallow dose from nonpenetrating radiation (e.g. beta radiation and low energy photon radiation). This is not true for the urinary bladder or the prostate gland, which makes the bladder a more appropriate choice for a prostate surrogate organ. 2.0 Evaluation The organ-specific dose conversion factor (DCF) used to determine the prostate dose from a dosimeter reading, changed from those used for the testes to those used for the bladder. Since the DCFbladder
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