Drug discovery period

							                                                                                                                             Drug marketing
              Drug discovery period                             Drug development period
                                                                                                                          Line expansion period




Decision to                Lead                                                                                      Post-marketing
                                                                IND filed                             NDA
 seek new                identified                                                                                   surveillance
                                                                                                    approved
 agent for                                                                                                              initiated
  therapy                                                                                                                                          Marketing
                                                                                                                                                    support
                                         Candidate
                                                                             Clinical
                                        chosen and                                                               Drug
                 Chemicals                                                   studies
                                        confirmation                                                           launched
                 and natural                                                initiated                                           New clinical
                                          tests run
                  products                                                                                                      indications
                   tested                                                                                                         pursued
                                                                                          NDA
                                                                                        prepared
                                                                                           and
                                                                                        submitted


        Chemical                  Analogs          IND plan                                                                              New dosage
        synthesis                   and           established                                                                             forms and
         initiated,              derivatives           and                                                                               formulations
      natural source               tested           initiated                                                                             developed
        products
        identified

                                                                       Clinical Phases I, II, III                  Phase IV