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Letter from Bristol Myers Squibb

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5/4/2008
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April XX, 2008 John Q. Sample 123 Any Street Anytown, USA 12345-6789 Re: BiCNU® (carmustine) for Injection Reintroduction Dear Pharmacy Director, I am writing to inform you of the resolution of a previous supply shortage of BiCNU® (carmustine) for Injection, NDC: 0015-3012-38 (100 mg/vial, 3 mL diluent/vial). Effective immediately, BiCNU® is available through normal distribution channels with a changed package. While there has been no change to the carmustine, packaging for the diluent will change from a vial to an ampule, and the previous package/NDC will be phased out. This should result in a stable supply of BiCNU® for our customers. For new purchase orders, the new package/NDC will be as follows: BiCNU® (carmustine) for Injection 100 mg carmustine/vial and 3 mL sterile diluent/ampule New NDC: 0015-3012-60 We regret any inconvenience that the previous shortage may have caused and thank you for your continued support of Bristol-Myers Squibb products. If you have any questions related to this announcement, please do not hesitate to call Customer Service at 1-800-631-5244, option 1. Sincerely, Stuart C. Dorman Associate Director, US Oncology Strategy & Operations V5-D0086 – April, 2008

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