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Asian Menopause Survey March 2007 by AmnaKhan

VIEWS: 99 PAGES: 39

									Asian Menopause Survey
March 2007
Hans Rekers VP Medical Affairs NV Organon

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Objectives
To provide : Current insights in women’s thoughts and

feelings about menopause and HRT:
 Their views       Their perceptions Their concerns Their fears Their beliefs Their experiences Their needs

Today

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European Menopause Survey
2005

By Linda Abrams March 8th 2005

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Healthcare

Research design & methodology Asia Pacific
Women’s age 45-60
Sample size 1000

Europe
45-60
4201

Time
Countries

March 2006
China, Hong Kong, Taiwan,Malaysia, Thailand

January 2005
Netherlands, UK Belgium, Spain , Germany, France, Switzerland,

Interview

Face to face

Telephone

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Survey on Menopause in ASIA PACIFIC Sample
AGE GROUP MALAYSIA CHINA HONG KONG TAIWAN THAILAND

45 – 49 50 – 55
56 – 60 TOTAL

105 135
60 300

90 150
60 300

30 50
20 100

45 75
30 150

45 75
30 150

Total Number of Respondents = 1000
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Survey on Menopause in ASIA PACIFIC

Questionnaire design
 Demographic profile
 Attitudes, Interests and Opinions regarding to:
 Menopause
 Breast

 Sexual well-being

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Findings
 Menopause  Breast  Sexual well-being

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Almost half the Asian menopausal women are affected by menopause symptoms
Q17. Feeling about the menopause

46%
Total 7% (N=1000) 39% 28% 23% 3%

Affects me a lot Does not affect me that much Don't know

Affects me somewhat Does not affect me at all

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Symptoms experienced are in general mild Sleeplessness most mentioned
Q15 Currently experiencing or have experienced any symptoms in the past 5 years?

% of women
100%
4%

80%

38%
11%

40%
9%

44%
8%

44%
7%

42%
11%

60%

40%

20%

51%

51%

48%

49%

43%
Reduced sex drive

0%

Sleeplessness

Irritability

Mood swings/mood changes
No

Headaches or migraines

Yes, mild

Yes, severe

Don't want to share

Total (N=1000)
Base: All respondents
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Reasons to seek treatment in Asia
Sleeplessness Hot flushes Headaches/ migraine Mood swings Irritability Depression Reduced sex drive Vaginal pain Involuntary loss of urine Don't know/ all the same
0

42 37 35 32 25 20 17 13 9 12
10 20 30 40 50 60 70

% women

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Reasons to seek treatment in Europe
Hot flushes Sleeplessness Mood swings Irritability Depression Headaches/ migraine Vaginal pain Reduced sex drive Involuntary loss of urine Operation Menstruation problems Other 0

59 21 17 15 14 10 8 7 5 5 4 5
10 20 30

Base: women who sought treatment for menopausal symptoms n=2721

40

50

60

% women
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Usage of treatments in Europe
Ever used Current use

HRT

42 22 31 19 8 5 35 55
0 10 20 30 40 50

Natural or herbal

Anti-depressants

None of these

60

% women

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Usage of treatments in Asian
19
7 37 32 2 1 45 59
0 10 20 30 40 50 60

Ever used Current use

HRT

Natural or herbal

Anti-depressants

None of these

% women

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HRT usage in Asia by country/regions
35 30

ever used current use

30.6 25

% of women

25 20

15.3
15 10 5 0

11 6 2.1 0.9 China Malaysia

12 9.3 6.3

Taiwan

Thailand

Hongkong

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General feeling about HRT

9%
Negative
Negative Positive Don't know

48%

43%

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Largest hurdles preventing the use of HRT

Breast problems Info about increased risk of heart disease Will not alleviate symptoms Weight gain Increased risk of breast cancer
0%

9% 24% 27% 32% 45%
10% 20% 30% 40% 50%

% of women

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In cr ea se d
% of women

ris k of br e

20%

40%

60%

80%

as t

0%
25% 8% 8% 17% 17% 17% 38% 25% 19% 25%

Hong Kong (N=12)

Thailand (N=16)

Largest hurdles preventing the use of HRT

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25% 6% 13% 6% 13% 12% 24% 41% 41% 12% 47% 6%

Malaysia (N=17)

First, spontaneous

ca nc W er D ei r. gh W re tg or co rie ai m n d m ab en ou de ts d to /e st Em op ot H io R na T In lc cr ha ea ng se es d In ris fo k .A of bo br ut ea in st cr ca ea nc se W er d ei ris gh W k tg of i ll ai no he n ta ar td lle ise via as te e sy m Br pt ea om st s In pr cr ob ea le se m d s In ris fo k .A W of i ll bo br no ut ea ta in st cr lle ca ea via nc se te er d sy ris m k pt of om he s ar td ise as W e ei gh Br tg ea ai st n pr ob le m s

Others, spontaneous

18%

Few women have ever considered HRT. Far more would be confident to use upon the doctor’s advise
Q35. Confidence to use HRT with doctor’s advice
Total (N=321)

Q36. Ever considered treatment for menopausal symptoms
20% 66% 14%

Total (N=585)

12%

42%

25%

11% 10%

China 3% (N=128) Taiwan 5% (N=107) Hong Kong (N=72) Thailand (N=116) Malaysia 6% (N=162)
19%

32%

36%

21% 5%

China (N=71) Taiwan (N=75) Hong Kong (N=63) Thailand (N=14) Malaysia (N=98)

23%

56%

21%

34%

34%

7%

21% 4% 14%

11%

81%

8%

63%

24%

76%

31%

47%

2% 11% 9%

14%

71%

14%

41%

26%

9%

17%

25%

54%

21%

Agree strongly Disagree slighty Don't know

Agree slightly Disagree strongly

YES

NO

Don't know

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Findings
 Menopause  Breast  Sexual well-being

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Self breast examination
100% 80% 60% 40% 20% 0%

30%

17%

% of women

70%

83%

Asia (N=1000)
YES

Europe(N=4201)
NO

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Worries about getting breast cancer

100% 80% 60% 40% 20% 0%

% of women

50%

45%

50%

55%

Asia (N=1000)
YES

Europe (N=4201)
NO

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Perceived risk factor for developing breast cancer (Europe)
85 61 27 19 17 16 14 11 9 9 5 7
0 10 20 30 40 50 60 70 80 90 100

Hereditary factors HRT Increased breast density Natural hormone levels Removal of ovaries Birth of first child at older age Weight gain before menopause Brittle bones Late menopause First menstruation before the age of 12 Waist-hip ratio Don't know

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Perceived risk factor for developing breast cancer (Asia)

Heredital factors HRT Removal of ovaries First menstruation before the age of 12 Waist-hip ratio Late menopause Weight gain after menopause Birth of first child at an older age Brittle bones Natural hormone levels Increased bone density

50 24 14 7 3 13 16 15 9 24 21

% women

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Largest hurdles preventing the use of HRT

Breast problems Info about increased risk of heart disease Will not alleviate symptoms Weight gain Increased risk of breast cancer
0%

9% 24% 27% 32% 45%
10% 20% 30% 40% 50%

% of women

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Perceived differences between various kinds of HRT (Europe)
Number, amount and kind of hormones Number and kind of side effects or risk factors Effectiveness in alleviating menopausal symptoms Way of administrating Safety of therapies Bleeding Effect on breasts Other Don't know
0 10

45 18 14 5 2 2 1 5 33
20 30 40 50

99% of women are not
aware of differences between HRT’s in relation to breast

% women

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Perceived differences between various kinds of HRT (Asia)

94% of
women are not aware of differences between HRTs in relation to breast
6% 39% 22% 27% 24% 19% 18% 23% 18%

Effect on breasts Effective in alleviating symptoms Brand name No. and kind of s/e Amount of hormones No. and kind of hormones No. and kind of risk factors Safety of the therapies Don't know

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Findings
 Menopause  Breast  Sexual well-being

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Reduced sexual functioning
Experience reduced sexual functioning and/or reduced libido

4% 25% 71%
Yes No Don't Know

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Discomfort during sex
Experienced vaginal pain, dryness or discomfort during sex 6%

19% 75%

Yes No Don't Know

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Reduced sexual interest has a negative impact

On relation with partner: On femininity

66% 64%

On quality of life

65%

On self esteem

34%

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Importance of sexual relationship before and after the menopause
Before menopause
Total (N=1000)
19% 55% 19% 3% 4%
8% 37%

Now
40% 11% 5%

China (N=300)

19%

57%

22%

2%

7%

43%

40%

7%

2%

Taiwan (N=150)

15%

55%

19%

10% 1%

9%

31%

41%

17%

2%

Hong Kong (N=100)

10%

60%

29%

1%

3%

31%

58%

8%

Thailand (N=150)

12%

51%

23%

5% 9%

3%

33%

39%

15%

10%

1%

Malaysia (N=300)

28%

54%

9%

7%

12%

38%

33%

10%

7%

Very important

Important

Unimportant

Very unimportant

Don’t know

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Willingness of all respondent to seek or take treatment, if confronted with sexual symptoms

Seek treatment

Take medication/drugs

not
Total (N=1000)

not
6% 24% 69% 7%

31%

63%

YES

NO

Don’t know
Base: All respondents

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Willingness to take HRT for sexual problems
Take hormone replacement therapy

Not
19% 71% 9%

YES

NO

Don’t know

Base: All respondents

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More than half the women don’t discuss problems with partners, only 6% with their doctors
Never discussed Female friends Family 1 Friends Doctor Partner
0

56 12

7 6
18
10

1
20 30 40 50 60

% women
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With improved sexual functioning I would enjoy life more

5% 34% 61%

Yes No Don't know

Base: All respondents

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75% women would talk about it if doctors bring it up
If my doctor would bring up the subject of sexual problems himself, it would trigger me to talk about it

2%

23% 75%

Yes No Don't know

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Summary and conclusions
Sleeplessness and hot flushes are most common reason for seeking treatment for Asian women HRT use is much lower in Asian than in European women
Breast cancer risk (and other perceived AEs) major hurdle for acceptance of hormone treatment

Perceived efficacy differences between HRT options, no awareness in differences in breast (cancer) effects

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Summary and conclusions
Most women experience reduction in libido / sexual functioning
This affects their femininity, QoL and self esteem

Most women uninformed about treatment options and/or unwilling to seek or take treatment
6% discuss symptoms with their doctor, 75% willing to discuss in doctor initiates

61% would enjoy life more if sexual functioning improved
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Menopausal womens’ needs
Adequate information, less media driven scare stories
Doctors perceptive of the potential symptoms (and worries) they may experience - but dare not discuss pro-actively

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