Uterine Tumors fsm.ac.fj

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Excellence… "He should sweep streets so well that all the host of heaven and earth will pause to say, 'Here lives a great streetsweeper who did his job well" – Martin Luther King Jr. Uterine Tumors Dr. Venkatesh Murthy Shashidhar Senior Lecturer in Pathology Fiji School of Medicine • Endometrial tumors Classification: • Benign - Endometrial polyps • Malignant – Endometrial Carcinoma • Myometrial tumors • Benign – Leiomyoma • Malignant – Leiomyosarcoma • Tumor like conditions • Adenomyosis • Endometriosis • Gestational & Placental Tumors • Hydatidiform mole – Partial & complete. • Choriocarcinoma Leiomyomas: • • • • • • • • Commonest tumors 25% of women. Also called as “Fibroids” Common in blacks. Estrogen responsive, regress after castration or menopause. Rapid increase during pregnancy Whorls of smooth muscle, well demarcated Asymptomatic, bleeding or Press on bladder Abortion, malpresentation, PPH etc. Leiomyomata Uterus: Leiomyomata Uterus Leiomyoma: Leiomyoma: Leiomyosarcoma: Leiomyosarcoma: Endometrial Polyp: Adenomyosis Uterus: Uterus Adenomyosis: Adenomyosis: Adenofibroma: Adenofibroma Uterus: Endometrial Carcinoma: • • • • Decreasing Cx ca - so commonest (7%) Mainly in postmenopausal women. >40Y Presents with bleeding so early detection. Obesity, diabetes, hypertension & infertility Estrogen secreting ovarian tumors & prolonged estrogen therapy are risk factors. • Presents as diffuse or polypoid growth. Endometrial Carcinoma: Endometrial Carcinoma Endometrial Carcinoma: Molar Pregnancy Uterus Partial Mole: Hydatidiform Mole: Invasive Mole: Hydatidiform Mole: Complete Mole: Mole Ultrasound: Complete • All villi cystic • No fetal parts • Diffuse Mole Partial • Partially cystic • Fetal parts may be • Focal hyperplasia of trophoblasts • 69xxy or 92xxxy • (ovum & sperm) • Rare carcinoma trophoblastic hyperplasia • 46xx of sperm • Choriocarcinoma common. Choriocarcinoma: Choriocarcinoma: Summary: • Endometrial hyperplasia – polyps • Endometrial Carcinoma – Old age, early diagnosis. • Leiomyoma – benign hyperplasia, hormone dependent. Presents with mass Infertility and DUB. • Leiomyosarcoma – rare. •Learning is the beginning of wealth. •Learning is the beginning of health. •Learning is the beginning of spirituality. •Learning is where miracles begin. – Jim Rohn

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