Meningitis - Get as PowerPoint by sammyc2007

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									“When ever there is a „gap‟ between where you are now and where you want to be, you have a problem”
(Hayes 1989)

Problem Solving: Mental activity leading from where you are to a more desired „goal state‟
(Kurfiss 1988)

( and learning from the experience)

Meningitis
Dr. Venaktesh M. Shashidhar
Associate Professor of Pathology Fiji School of Medicine

Meningitis:
Inflammation of Meninges - Leptomeningitis Meningoencephalitis – Brain & meninges Types:
Infective – Septic & Aseptic (B, F, TB & V)  Chemical – Drugs  Carcinomatous - metastasis


Headache + Neck stiffness. Neurological deficits Complications: Encephalitis, Infarction, Abscess, Hydrocephalus & empyema.

Septic Meningitis

Septic Meningitis

Septic Meningitis

Septic Meningitis

Septic Meningitis

Septic Meningitis

Septic Meningitis-Microscopy

Septic Meningitis-Microscopy

Septic Meningitis-Spinal fluid

Septic Meningitis-Spinal fluid

Septic Meningitis - Organisms
ORGANISM Escherichia coli Hemophilus influenzae Neisseria meningitidis Streptococcus pneumoniae PEAK AGE INCIDENCE GRAM STAIN

Neonates Gram negative rods Infants and Children Gram negative coccobacilli Adolescents and Young adults negative diplococci Gram Older adults or Children Gram positive cocci in chains

Brain Abscess:

Brain Abscess: CT Scan

Hydrocephalus:

Infarction Meningoencephalitis:
Mucormycosis in a Diabetic.

CSF-Examination
Cells Protein Glucose Appearance

N

0-4 lympho

0.1-0.4(n) 2.7-4.0 (n) Clear colourless

Septic > Poly

High
High

Low
normal

Turbid
Clear

Viral > Lymph
TB
> lymph

High

Low

Opalescent (cob-web)

Clinical details:
38 Year Fijian male Severe headache 2 months, Photophobia, Drowsy, seizure, vomiting. Bil. Papillary edema Responded to Mannitol + steroids Died in hospital Brain sections after limited autopsy.

Autopsy
Marked inflammtory infiltrate in meninges Superficial Cerebral edema (cortex)

Meningitis - Cryptococci
Round capsulated fungal organisms Lymphocytic infiltrate around

Summary:
Leptomeningitis Infective, Chemical Carcinomatous Head ache, Neck stiff ness. Septic & Aseptic types – CSF diagnosis Common causes, organisms. Complications:


								
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