Surveillance Systems for Infectious Diseases in Korea
Ok Park, Medical Officer, KCDC Trilateral Seminar on R & D Policies to Emerging And Re-emerging Infectious Diseases, December 14-16, 2005, Boston
Overall Incidence of Notifiable Infectious Diseases in Korea
* The cases of Tuberculosis, Hansen’s disease, and HIV/AIDS were excluded
Emerging Infectious Diseases in Korea
Leptospirosis, Legionellosis outbreak (1984) HIV Infection (1985) Entero-hemorrhagic E-coli (O157) infection (1998)
Vancomycin intermediate susceptible Staphylococcus
aureus infection (1999)
Brucellosis (2002) Botulism (2003)
Reemerging / Increasing Infectious Diseases in Korea
Reemergence of vivax Malaria (1993) Reemergence of Rabies (1998) Increase in Food-borne diseases
• Shigellosis : caused by Shigella sonnei • Food poisoning • EHEC infection : increasing since first outbreak in 2003
Increase in Hantavirus hemorrhagic fever syndrome, Scrub typhus, Leptospirosis (since 1998) Increase of HIV/AIDS
Reported Cases of Shigellosis by Year
10,000 8,000
No. of cases
6,000 4,000 2,000 0
1910
1919
1928
1937
1946
1955
1964
1973
1982
1991
Year
2000
Reported Cases of Measles by Year
40,000 35,000
No. of cases
30,000 25,000 20,000 15,000 10,000 5,000 0
Adapted measles elimination strategy and conducted mass immunization campaign, 2001
1955
1959
1963
1967
1971
1975
1979
1983
1987
1991
1995
1999
Year
2003
Reported Cases of Malaria by Year
18,000 16,000 14,000
No. of cases
12,000 10,000 8,000 6,000 4,000 2,000 0
Adapted malaria elimination strategy in 1999 and launched DPRK project in 2001
1961
1964
1967
1970
1973
1976
1979
1982
1985
1988
1991
1994
1997
2000
Year
2003
Enhancement of Infectious Disease Surveillance and Response
Increase of Emerging and Re-emerging Infectious Disease • Adopt Proactive Strategy for Communicable Disease (Control→ Elimination) • Build Infrastructure to Respond Communicable Disease
Organization Legislation
Human resources •Revision of •FETP •FMTP CDPL • KCDC •Onsite •Sentinel supervision • Formation surveillance •Cyber of Task •Immunieducation Forces •Training zation courses Registry
IT
•EDI •DB
Stockpiling
•Vaccine
R&D
•Vaccine
•Antibiotics •Diagnosis
•Modeling •Antiseptics •Therapy •Serum •PPE •Info bank sharing •Ventilators
Reporting System of Notifiable Diseases
Physicians
Report (Tel/Fax) Feedback
Health Center (District level)
Report (EDI) Feedback
Specimen Referral
Feedback
Dept. of Health (Provincial level)
Report (EDI) Feedback
Prov. Inst. of Health & Environment
KCDC
Specimen Referral
Feedback
Enhancement of Legal Framework
Revision of Communicable Disease Prevention Law • Enacted in 1953 • Revised in 2000 to strengthen legal basis for EID
- Extend diseases for notification (3 groups 29 diseases to 5 groups 64 diseases) - Change notification criteria - Shorten the reporting time - Stipulate Notification form, Notification process, Scope of notification of each disease Punishment for delinquent reporting
Classification and Reporting Time of Notifiable Infectious Diseases
Group
1 2 3
Classification criteria
- Spread rapidly and pose a high level of health risk to national health or Requiring immediate control measures at the onset of an outbreak
-Vaccine preventable communicable diseases that are subject to the national immunization program - Require continuous monitoring or establishment of preventive measures because of the potential for an outbreak - Newly emerging diseases within Korea - Reemerging in Korea or importable diseases from overseas that require urgent prevention measures - Not included in Groups 1 and 4 that require surveillance to detect outbreaks, Designated by the MOHW
Time
Immediately
Immediately Within 7days Immediately Within 7days
4 Appo inted
Adapt IT for surveillance and Enhance analysis and Feedback
Adapt IT for surveillance
• • • • Electronic data interchange system for reporting Data management program Statistical program Develop Disweb as a portal site for sharing information on communicable diseases
CDWR(Communicable Disease Weekly report) CDMR(Communicable Disease Monthly Report) Statistical Year Book Press releases
Enhance Data Analysis and Feedback
• • • •
Information Flow
Management Management program program
PHC DB Prov. DB
Management program
Management program Management program
Doctor
TEL,FAX
Health center
EDI
Province EDI
KCDC
Database
Sentinel site
Feedback
Statistic DB Statistical Program
EDI System for Reporting
Data Management Program
Statistical Program of Communicable Diseases
Portal Site for Information on the Communicable Disease (http://dis.cdc.go.kr)
English version of Disweb
http://dis.mohw.go.kr/english/index.htm
Establishment of Various Surveillance Systems
Sentinel Surveillance by the CDPL • Influenza, Viral hepatitis A, B, C, STDs • Imported Parasitic Diseases, VRSA infection, CJD Sentinel surveillance on the voluntary basis • Pediatric Sentinel Surveillance, Viral conjunctivitis Network for information sharing and surveillance • Infection specialists network (2002) • EpiNet (2003) Syndromic Surveillance and Rumor Surveillance System • Emergency room based syndromic surveillance (2002) • Enhanced syndromic surveillance during major international events (2003) • K- ProMed
Website for sentinel or syndromic surveillance
Website for Influenza Surveillance
(Korean/English version)
Human Resources Development and Collaboration with Private Sector
Development of Human Resources
• Field Epidemiology Training Program (1999) • Field Management Training Program (2002) • Training program by each Div. - Training for communicable disease surveillance : 3 to 4 times a year
Enhancement of Collaboration with Private Sector
• Development and operation of sentinel surveillance in the collaboration with private sector • Co-hosting of seminar, conferences • Research Project
Gaps for Infectious Disease Surveillance
Insufficient capacity at local government
• Lack of human resources at local government to respond to emerging infectious diseases
• Frequent rotation of health care workers
Insufficient operation of various surveillance system
• Development of various surveillance systems which can serve as an early warning system • Lack of experts to operate each surveillance system
Gaps for ID Surveillance
Insufficient integration among surveillance systems • Insufficient integration between Notifiable Disease Surveillance & laboratory surveillance Low participation rate for notification from physicians • Low notification rate of notifiable diseases - Shin et al, 1994, notification rates of group 1 and group 2 diseases are respectively: 71.0% (95% PI, 96.2 - 75.3), 20.0% (95% PI, 18.9 – 21.3) - Shin et al, 2003, small scale survey result, notification rates of group 1, 2, & 3 are 76.4%, 50.5% & 43% respectively
- Survey in one city, 2002, report always (28%) ; report generally (37%), report sometimes (18%) ; report rarely (9%) ; no experience of infectious disease (8%), N=727
Future Plans
Development of web-based reporting system
• Convenience of data management • Real-time analysis
Integration of Notifiable Disease Surveillance and Laboratory Surveillance • Comprehensive surveillance • Increase notification rate
Future Plans
Extension of electronic reporting system to private sector • Convenience of notification from the private sector • Enhance notification rate automatically • Decreasing duplicated work in public health sector Development of human resources • Continuous training to develop human resources Collaboration with private sector to enhance participation in disease surveillance • Enhance R & D • Operation of various surveillance system
Thank You