Module Two Current Status of Diabetes Care at Mayo Clinic Hospital
Curtiss B. Cook Professor of Medicine Mayo Clinic College of Medicine
Learning Modules
Module no. 1 2 3 4 5 6 7 Topic Hyperglycemia and hospital outcomes Current status of diabetes care at MCH Initial recognition, triaging, and management Principles of pharmacologic management: Insulin 1 Principles of pharmacologic management: Insulin 2 Review of policies and procedures Getting patient ready for discharge
This module will describe current knowledge of our hospital diabetes care and ongoing efforts to improve
Objectives
• Discuss the challenges to managing hyperglycemia in the hospitalized patient • Describe the current status of diabetes management at MCH • Use operational definitions for inpatient glucose control
Challenges to managing hyperglycemia in the hospital
• Type of hyperglycemic patients
– Patients with preexisting diabetes – Patients with undiagnosed diabetes – Patients with stress hyperglycemia
• Types of hospitalized patients
– – – – Short stay Elective/Urgent/Emergent Post-surgical Critically ill
Patient population with hyperglycemia is heterogeneous
Challenges to managing the hospitalized diabetes patient
• Variables exacerbating hyperglycemia
– Increased counter-regulatory hormones – Decreased insulin secretion – Decreased insulin sensitivity – Accelerated glucose production
• Increased protein catabolism • Increased lipolysis • Medications (steroids, vasopressors)
Challenges to managing the hospitalized diabetes patient
• Care-related issues
– Incorrect classification of diabetes – Problem overlooked or not addressed – Fear of hypoglycemia – Nutrition
• Type of nutritional support • Missed injections/missed meals • Mismatching of insulin with meals
– Unpredictable timing of procedures
Distribution of diabetes cases, by discharge service
50 40
Percent
30 20 10 0
Primary Care Surgical Cardiology Transplant Other
Distribution (%) of bedside glucose, non-ICU, MCH 2001 to 2004
First 24h average (n=2,408)
40 35 30
Overall average Staying hyperglycemic
Admitted hyperglycemic
25 20 15 10 5 0 0 50
100 150 200 250 300 350 400 450
42% of patients admitted with poor control (200 mg/dl) 40 remained in poor control at 35 time of discharge
30
Last 24h average (n=2,318) Discharged hyperglycemic
need to do a better job 20treating hyperglycemia
15 10 5
25 We
Results of similar survey regarding operational definitions of hyperglycemia among MCH providers
X = 140 mg/dl
Need to develop internal consensus so everyone is practicing the same
Frequency of hypoglycemia and hyperglycemia
No. events/person/100 measurements
30
30
Hypoglycemia frequency
20
20
Hyperglycemia frequency
10
10
0
0
<70
<60
<50
<40
>200
>250
>300
>350
>400
Bedside glucose (mg/dl)
Bedside glucose (mg/dl)
Hypoglycemia rare, hyperglycemia common
Which is the bigger problem?
Units of insulin delivered, last vs. first 24 hours of hospitalization
100%
Percent in each category
80% 60% 40% 20% 0%
Tertile of BedGlucav Mean glucose
1
2
3
129
165
218
Increased
Decreased
No change
Not just clinical inertia (failure to intensify treatment), but also…
Negative therapeutic momentum (decrease in treatment despite hyperglycemia)
Documentation of diabetes
N= 90 charts reviewed
100
Percent of cases
80 60
Not documented
40 20 0
Diabetes in admission note Diabetes or hyperglycemia in daily progress note Diabetes or hyperglycemia in discharge note Need for diabetes or hyperglycemia follow-up
Documented
Diabetes often overlooked after admission
Diabetes and assessment of inpatient glucose control
100
Percent of cases
80 60 40 20 0
Beside glucose measurements ordered Bedside glucose values recorded in progress notes Assessment of glucose control
Not documented Documented
Bedside glucose ordered, but often not tracked
Final Summary
• Hospitalizations are common in diabetes—you will see these patients • Good glycemic control is essential for good outcomes • There is room to improve inpatient diabetes care at MCH
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