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Characterizing Speech Language Pathology Outcomes in Acute Stroke Rehabilitation

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Characterizing Speech and Language Pathology Outcomes in Stroke Rehabilitation Brooke Hatfield, MS, CCC-SLP Deborah Millet, MS, CCC-SLP Janice Coles, MS, CCC-SLP Julie Gassaway, MS, RN Brendan Conroy, MD Randall J. Smout, MS The focus of our time together     Describe Practice-Based Evidence Clinical Practice Improvement (PBE-CPI) design Describe the Post Stroke Rehabilitation Outcomes Project (PSROP) Examine who receives SLP services in poststroke rehabilitation Examine how SLPs spend their time with patients in post-stroke rehabilitation The focus of our time together     Review the results of early data analyses regarding outcomes Consider clinical implications of the findings Consider limitations and future data queries Try not to think about the mojitos we’re missing out on by being here Practice-Based Evidence for Clinical Practice Improvement  Susan Horn, PhD Institute for Clinical Outcomes Research 699 E. South Temple, Suite 100 Salt Lake City, UT 84102-1282 801 – 466- 5595 shorn@isisicor.com PBE-CPI Study Design  Content and timing of individual steps of a health care process, to determine how to achieve:  Superior medical outcomes  Least necessary cost  Across the continuum of care Goals of PBE-CPI  Improve/standardize process factors  Practitioner activities/interventions  Other interventions  Medications  “what we did” Goals of PBE-CPI  Control for patient factors  Psychosocial/demographic Factors  Disease(s)  Severity of Disease(s)  Physiologic signs and symptoms  Multiple points in time  “for whom we did it” Goals of PBE-CPI  Measure outcomes  Clinical  Health status  Length of stay  Discharge location  “how far we got” and “how much it cost to get there” Characteristics of a PBE study     Non-experimental – follows outcomes of treatments actually prescribed Inclusive – uses pt. populations undergoing routine clinical care Pragmatic– uses actual clinical outcomes Lower cost Advantages of PBE study    Can simultaneously study outcomes of a large variety of treatments Can ask complex questions regarding treatment sequence effects, conditional effectiveness Can look at treatment effectiveness in whole clinical populations   More heterogeneous – reflecting clinical reality Less pt. selection bias – no requirement to consent PBE-CPI: an alternative to Randomized Control Trials PBE – CPI Patient Variables Use severity of illness to measure comorbidities and disease severity All patient qualify RCT Patient Variables Eliminate patients who could bias results based on comorbidities and more serious disease 15% of patients qualify PBE-CPI: an alternative to Randomized Control Trials PBE-CPI Process Variables Methods for stabilization RCT Process Variables Treatment protocol Measure all processes and use analysis findings to develop protocol associated with better outcomes Specify explicitly every important element of the process of care for both treatment and control arms PBE-CPI: an alternative to Randomized Control Trials PBE-CPI Outcome Variables RCT Outcome Variables Dynamic improvement based on combinations of interventions Result Effectiveness research (usual conditions) Change based on one protocol Result Efficacy research (ideal conditions) PBE-CPI: an alternative to Randomized Control Trials  PBE-CPI Hypotheses many and vague Alternatives not discrete Local knowledge contributes  RCT Hypothesis clear   Alternatives discrete   Not depend on local knowledge PBE-CPI: an alternative to Randomized Control Trials  PBE-CPI Confounders affect outcomes and are interesting Effects are large  RCT Confounders not interesting   Effects are small Alternatives to RCTs in the Literature  Results from 2 NEJM studies “Average results of the observational studies were remarkably similar to those of the randomized, controlled trials” New England Journal of Medicine 2000 (June 22, 2000) 342: 1878-92 Alternatives to RCTs in the Literature  Conclusions from JAMA study “Significant between-study variability was seen as frequently among RCTs as between RCTs and non-randomized studies.” “…may reflect differences in true treatment effects under different study settings and in different populations.” JAMA (Aug 2001) 286, 7:821-830 So what is a PBE-CPI study?  Three-dimensional measurement framework  Patient variables, process variables, and outcomes   Adjusts for severity of illness Led by a transdisciplinary team that      Develops and frames questions Defines variables for study Gathers data Interprets findings Implements findings Measuring and Adjusting for Severity of Illness  Comprehensive Severity Index (CSI®)  2,200 + individual criteria  5,500 disease specific groups   Disease-specific and overall severity levels on a scale of 0 – 4, continuous Fixed times for inpatient reviews    Admission Maximum Discharge review Components of a PBE-CPI Study      Development of data collection tool to record practices for each point of contact Patients enrolled, normal practices recorded via point-of-care forms Retrospective chart review to record data regarding patient, processes, and outcomes Retrospective chart review using CSI® Data analyzed and findings interpreted A Previous PBE-CPI Study  Nursing Home Study (NPLUS) 1996-1997     6 LTC provider organizations 109 facilities 2, 490 residents studied Outcomes     Developed pressure ulcer Healed pressure ulcer Hospitalization Systemic Infections A Previous PBE-CPI Study  Outcome: Develop Pressure Ulcer  More likely to develop a pressure ulcer if:        The patient was male The patient was >85 years old Static pressure relieving devices were used Dependency in greater or equal to 7 ADLs Signs of dehydration Weight loss of more than 5% in last 30 days Mechanical devices such as catheters were used A Previous PBE-CPI Study  Outcome: Develop Pressure Ulcer  Less likely to develop a pressure ulcer if:      Disposable briefs were used Toileting program was used Combination of newer SSRI and antipsychotic were used RN spent more than 15 minutes with the patient Fluid orders and nutritional supplements were used Pressure Ulcer Clinical Outcomes Post Implementation  Development of pressure ulcers for highrisk residents  decreased from 14% pre-implementation to 8.7% postimplementation  is still decreasing  Post-Stroke Rehabilitation Outcomes Project (PSROP)  Using PBE-CPI to investigate the “black box” of post-stroke rehabilitation   6 US sites, 1 New Zealand A study team at each site:       Physician Nursing Social Work Psychology PT/OT/SLP Therapeutic Recreation Post-Stroke Rehabilitation Outcomes Project (PSROP) Facility National Rehabilitation Hospital Univ. of Pennsylvania Med Center LDS Hospital Rehabilitation Ctr Legacy Health System Location Washington, DC Philadelphia, PA Salt Lake City, UT Portland, OR Site Director(s) B Conroy, MD R Zorowitz, MD D Ryser, MD F Wong, MD LA Sims, RN Type Freestanding Rehab Unit Rehab Unit Rehab Unit Beds 128 24 26 33 Stanford University Hospital Loma Linda Univ. Medical Center Palo Alto, CA Loma Linda, CA J Teraoka, MD M Brandstater, MD Rehab Unit Rehab Unit 17 40 Wellington/Kenepuru Hospitals Wellington, NZ H McNaughton, MD Rehab Unit 25, 20 PSROP Study Questions    Which patient characteristics are associated with improved post-stroke outcomes? Which treatment interventions or combinations are associated with improved outcomes (when controlling for patient characteristics)? What is the optimal intensity and duration of various post-stroke treatment interventions? PSROP Patient Variables       Age, gender, race Payer source Type and side of stroke Stroke location Admission FIM Case-mix group    Admission severity of illness Acute care hospital LOS Date/time of stroke symptom onset PSROP Process Variables       Rehabilitation LOS Medications Nutritional process Pain management Time to first rehab Oxygen use   Specific therapy interventions Intensity, frequency, and duration of therapy interventions PSROP Inclusion Criteria      Rehab diagnosis: ICD-9 code of 430-438.99, 997.02, or 852-853 18 years or older 1st inpatient rehab admission after current stroke If interrupted stay – remained in study if less than 30 day interruption No exclusion criteria or need for consent PSROP Data Collection     Supplemental documentation from all rehab disciplines at point of contact Retrospective chart review for Auxiliary Data Module (records data re: all variables) and CSI® March 2001 – March 2003 200 patients/site for consecutive stroke admissions PSROP Limitations      Reliance on chart review Limited acute care information No standard of initial stroke severity (e.g. NIH Stroke Scale) in all facilities CSI dependent on ICD-9 codes Point of care documentation    Train-the-trainer approach Burdensome to team members Paper – some may have been misplaced The Depth of the Data Set      141, 511 point of care forms 235 variables captured once for each patient 71 complication/process variables that depended on each patient’s length of stay 15 variables captured daily over length of stay Up to 8 variables per medication administered Point-of-Care Documentation All Clinical Services  Development of a taxonomy of rehab activities to capture in detail what clinicians do – it had to:    be quick (less than 1 minute) to complete record duration of activity and date of session break down into activities and interventions   Activities: general target area of the task – broad Interventions: strategies, cues, protocols, equipment, education, diagnostic tests Point-of-Care Documentation SLP Activities         Pre-functional Swallowing Face/Neck mobility Speech/Intelligibility Voice Verbal Expression Alternative/Non-verbal Expression Written Expression         Auditory comprehension Reading comprehension Problem solving/reasoning Orientation Attention Memory Pragmatics Executive functional skills Point-of-Care Documentation SLP Interventions      Adaptive and Compensatory Strategies Neuromuscular Interventions Modalities Devices Perception    Soft Tissue Work Education/Counseling Diagnostic Tests  Did not include standardized tests Point-of-Care Documentation Additional Data Points   Date Time spent in:       Professional level of treating clinician     Co-treatment Formal assessment Supervisory/team input Preparation of activities Group treatment SLP SLP-A SLP aide/tech SLP student S p eech & L an gu age T h erap y R eh ab ilitation A ctivities 16315 Patient ID : D ate of T herapy Session: S a m p l e T herapist: / T im e session begins: / : INTERVENTION CODES Duration of Activity Adaptive & Compensatory Strategies: E nter in 5 m inute increm ents. 01. M em ory strategies 02. M otor speech strategies P re-F unctional A ctivity 03. Sw allow ing strategies 04. D iet m odification/evaluation Sw allow ing 05. A ttention/focus strategies 06. Point/gesture strategies 07. V isual strategies/cueing F ace/N eck M obility 08. V erbal strategies/cueing 09. A uditory strategies/cueing Speech/Intelligibility 10. T actile strategies/cueing 11. A nalysis & sum m ary strategies/cueing Neuromuscular Interventions: V oice 12. O ral m otor treatm ent/R O M 13. R espiratory treatm ents V erbal expression 14. V ocal treatm ents 15. R esonance treatm ents 16. NDT A lternative/non-verbal expression 17. D PN S 18. T herm al tactile stim ulation W ritten expression 19. Postural aw areness M odalities: A uditory com prehension 20. EM G 21. B iofeedback 22. E lectrical stim ulation R eading com prehension Devices: 23. Incentive spirom etry 24. M em ory book/aids P roblem solving/reasoning 25. Speaking valves 26. A ugm entative com m unication devices O rientation 27. C om puter 28. V isi pitch 29. N asal m anom eter A ttention Perception: 30. R ight or left side aw areness strategies Soft Tissue W ork: M em ory 31. 32. 33. Strengthening Stretching M yofascial release Interventions E nter one intervention code per group of boxes. 15 06 P ragm atics Um, we’re going to need a few more boxes  Fast forward to when    All of the charts are reviewed for CSI and ADM information All of the point-of-care forms are scanned Data was “cleaned” There was a huge pile of information and data waiting to be organized! Data Analysis  Manageable bites      For analysis, “blocks” of therapy time were identified 1 block of SLP treatment = 3 hours 1 block of OT treatment = 4 hours 1 block of PT treatment = 6 hours Allows for comparison of groups while eliminating natural recovery time Grab your coffee, it’s time for statistics  Descriptive statistics  Study variables Used to compare patient, process, and outcome variables  Chi-tests   ANOVA  Continuous data Variables entered step-wise into model Importance determined via Wald chi-square  Logistic regression   General Outcomes of the PSROP US subjects: N = 1,161  Patient demographics   Male 51.8% White 61% Average age 66.0 Female Black 49.2% 23%  (18.6 – 95.5)  Common comorbidities    HTN 78.6% DM 30.8% CAD 22.5% General Outcomes of the PSROP  Process demographics   Average time from onset to admission to rehab: 13.8 days Mean rehab LOS: 18.6  The stroke itself    Right 44.2% Left 42.5% Hemorrhagic 23.2% Ischemic 76.7% Bilateral 10.5% General Outcomes of the PSROP  Severity  CMG    Mild (101-103): 11.5% Moderate (104-107): 39.6% Severe (108-114): 42.5%  Admission FIM (mean)    Total: Motor: Cognitive: 61.0 40.1 21.0   Severity of illness per CSI (mean): 20.7 Discharge to home: 81% Factors Associated with Outcomes  Interpreting outcomes   Associations vs. causations For patients who had __?__ on admission, they were more/less likely to achieve the outcome. For patients who spent more time in __?__, they were more/less likely to achieve the outcome.   Will need predictive validity studies to follow-up Outcome: Discharge Motor FIM Moderate stroke General Assessment Age Female PT Interventions Formal assessment Bed mobility OT Interventions Toileting Transfers SLP Interventions Speech intelligibility Auditory comprehension Voice Problem solving Brainstem/ Cereb Mod motor imp. Admission motor FIM Transfer Gait Home management Upper extremity control Advanced gait Medications General Interventions Anti-Parkinson Days onset to rehab LOS Opioid analgesics Atypical antipsychotics Outcome: Discharge Motor FIM Moderate stroke– 1st tx block only General Assessment Age PT Interventions Sitting OT Interventions Bathing SLP Interventions Auditory comprehension Female Brainstem/ Cereb Mod motor imp. Transfer Gait Feeding/Eating Voice Admission motor FIM General Interventions Days onset to rehab Medications Muscle relaxant Opioid analgesics LOS Old anticonvulsants Outcome: Discharge Cognitive FIM Moderate stroke General Assessment Aphasia Admission cognitive FIM PT Interventions OT Interventions Feeding/Eating SLP Interventions Auditory comprehension Problem solving General Interventions Medications Anti-Parkinsons Opioid analgesics New SSRIs Outcome: Discharge Cognitive FIM Moderate stroke– 1st tx block only General Assessment Aphasia Age Admission cognitive FIM PT Interventions OT Interventions Toileting SLP Interventions Auditory comprehension General Interventions Medications Anti-Parkinsons Old Anti-nausea Outcome: Discharge Motor FIM Severe stroke General Assessment Age Black race Mild motor impairment Admission motor FIM Admission cognitive FIM General Interventions Days onset to rehab Enteral feeding PT Interventions Formal assessment Bed mobility Gait Advanced gait OT Interventions Home management SLP Interventions Swallowing Orientation Reading comprehension Medications Anti-Parkinsons Modafinil Old SSRIs Outcome: Discharge Motor FIM Severe stroke– 1st tx block only General Assessment Age Severe motor impairment No dysphagia PT Interventions Bed mobility Gait Advanced gait OT Interventions Home management SLP Interventions Admission motor FIM No dysphagia Neurotropic meds General Interventions Days onset to rehab Enteral feeding Medications Other antidepressant Old SSRIs LOS Outcome: Discharge Cognitive FIM Severe stroke General Assessment Aphasia Mood and cognitive disturbance Admission cognitive FIM Functional mobility Community integration General Verbal expression PT Interventions Advanced gait OT Interventions Grooming SLP Interventions Auditory comprehension Orientation Bed mobility Problem solving Interventions LOS Medications Outcome: Discharge Cognitive FIM Severe stroke – 1st tx block only General Assessment Aphasia PT Interventions Advanced gait OT Interventions Bed mobility SLP Interventions Orientation Problem solving Mood and cognitive disturbance Race: other Max severity of illness Severe motor impairment Right brain stroke General Interventions Medications Admission cognitive FIM Days onset to rehab LOS Trends Across Disciplines  Patients involved in higher level activities in the first block of therapy despite their initial level of impairment were more likely to be “successful”    PT: early gait training OT: home management SLP: problem solving  What made the treating clinician decide to do these activities with severe patients?  They had “nothing to lose”. Why didn’t they decide to do these activities?  Staffing issues, size of the patient, time resources  Is there something to this?  The question: Does introduction of high-level SLP activities early in post-stroke rehabilitation correlate with improved outcomes for low to mid-level functioning communicators following stroke? What we (thought we) knew about SLP practice in inpatient rehab  Assessment leads to identified deficit areas Treatment plans target deficit areas directly   lead to improvement in the deficit area deficit in verbal expression + therapy targets verbal expression = measurable improvement in verbal expression Interventions and activities are introduced in a hierarchy of complexity •from simple to complex •more impaired patients start low in the hierarchy with simple tasks •more advanced patients start with more complex tasks because they can do them PSROP data indicate there may be a more effective way…  How to address the question?  ID a homogenous group  Set an outcome  Use logistic regression to ID the variables positively associated with achieving the outcome Identifying a Homogenous Group  The patient subset   n=397 At least 1 documented SLP session Over 90% of patients at 5 US sites  1 - 8 blocks (3 hour chunks) of SLP services Removed labeled aphasia    Concern over inaccurate recording More variability in treatment approaches for patients without aphasia  Removed patients at A FIM 6, 7 for Aud Comp and Verbal Expression Identifying a Homogenous Group  Low-level communicators   Admission FIM 1 – 3 for Comprehension alone Admission FIM 1 – 3 Comprehension paired with FIM 1 – 3 Verbal Expression  Mid-level communicators   Admission FIM 4 -5 Comprehension alone Admission FIM 4-5 Comprehension combined with Admission FIM Verbal Expression 4 -5 Identifying a Measurable Outcome  Success  Change in FIM at discharge (D FIM): Verbal Expression and Auditory Comprehension  Low-level communicators  Expression: increase to > Level 4 Comprehension: increase by 2 levels  Mid-level communicators  Expression: increase to Level 6 or higher Comprehension: increase to Level 6 or higher Classifying SLP Activities  Simple  Swallowing, speech intelligibility, voice, orientation, attention, pre-functional  Mid-level  Verbal expression, alternative/non-verbal expression, written expression, auditory comprehension, reading comprehension, memory, pragmatics  Cognitively-linguistically complex  Problem solving/reasoning, executive functioning skills Amount and Timing of Treatment Provided  397 patients averaged:    16.4 SLP sessions 11.4 days 602 minutes Patients per Block of SLP Treatment Number of Patients 100 80 60 40 20 0 1 2 3 4 5 6 7 8 Blocks of Treatment Who were these patients? Short (1 block) Mean age (years) 66.1 Medium (5 blocks) 56.7 Long (8 blocks) 67.3 Side of lesion (%) right left bilateral 50.6 34.5 12.6 43.3 33.3 20.0 58.8 35.3 5.9 Site of lesion (%) brainstem subcortical cortical 18.4 31.0 37.9 36.7 23.3 33.3 17.7 11.8 58.8 Who were these patients? Short (1 block) Medium (5 blocks) Long (5 blocks) Mean admission Motor FIM 44.5 34.5 28.9 Cognitive FIM CSI 19.9 18.5 15.6 24.0 17.4 20.9 Intensity of SLP services Short (1 block) Medium (5 blocks) Long (8 blocks) Mean LOS (days) 12.2 23.6 34.7 Days of SLP sessions SLP sessions during rehab SLP minutes during rehab 5.0 6.2 214 16.3 24.8 914 24.8 39.7 1439 % Time Across Short Stay (1 Block Total) Problem solving 16% Alt/Nonverbal 0% Pragmatics 0% Written expression 3% Speech 7% Attention 5% Reading comprehension 6% Orientation 5% Verbal expression 12% Voice 2% PF/Not related 2% Executive functions 5% Swallowing 19% Memory 9% Auditory comprehension 9% % Time in 1st block only; Short Stay Low level communicators (Comp 1 -3) Alt/Non-verbal 1% Problem solving 13% Pragmatics 0% Executive functions 3% Swallowing 29% Written expression 1% Reading comprehension 4% Auditory comprehension 10% Verbal expression 10% Orientation 9% Speech 3% Attention 4% Memory Voice 0% 11% PF/not related 2% % Time in 1st block only; Short Stay Mid level communicators (Comp 4-5) Executive functions 6% Alt/Non-verbal 0% Pragmatics 0% Written expression 3% Reading comprehension 6% Memory 8% Auditory comprehension 8% Problem solving 18% Swallowing 16% Speech 11% Attention 6% Voice 2% Orientation 1% Verbal expression 14% PF/Not related 1% Complexity of activities (% time) for Short Stay (1 block) 45 40 35 30 25 20 15 10 5 0 Simple Mid Complex Trends for a Short Stay   Averaged 6.2 SLP sessions over 12.2 day LOS Patients had more:   R CVAs Cortical lesions   Discharge: home Least amount of:   Cognitive and Motor FIM change Time in simple SLP activities; 1st block % Time Across Medium Stay (5 blocks) Problem solving 19% Executive functions 1% Swallowing 25% Alt/Non-verbal 1% Written expression 3% Pragmatics 1% Memory 5% Reading comprehension 7% Auditory comprehension 9% Attention 7% Speech 6% Orientation 4% Verbal expression 10% Voice 2% PF/Not related 0% % Time in 1st block only; Medium Stay Low level communicators (Comp 1-3) Executive functions 2% Pragmatics 1% Alt/Non-verbal 1% Memory 2% Written expression 4% Reading comprehension 7% Verbal expression 8% Auditory comprehension 11% Orientation 5% Speech Attention 4% 3% Problem solving 13% Swallowing 39% Voice 0% PF/Not related 0% % Time in 1st block only; Medium Stay Mid level communicators (Comp 4-5) Alt/Non-verbal 0% Pragmatics 1% Memory 3% Reading comprehension 4% Problem solving 14% Executive functions 2% Swallowing 39% Speech 7% Attention 6% Orientation 4% Voice 3% Written expression 4% Verbal expression 7% PF/Not related 0% Auditory comprehension 6% Complexity of Activities for Short and Medium Stays 45 40 35 30 25 20 15 10 5 0 Simple Mid Complex 1 block 5 blocks Trends for a Medium Stay    Averaged 24.8 SLP sessions over 23.6 day LOS Younger (56 years) Patients had more:    R CVAs Brainstem lesions Time in simple activities in 1st block  Swallowing  Time in auditory comp (in low level group)  Discharge: institution % Time Across Long Stay (8 blocks) Problem solving 20% Alt/Nonverbal 0% Written expression 4% Pragmatics 0% Memory 4% Attention 11% Speech 7% Orientation 4% Voice 2% Executive functions 2% Swallowing 25% Auditory comprehension 5% Reading comprehension 8% Verbal expression 8% Not related 0% % Time in 1st block only; Long Stay Low level communicators (Comp 1-3) Written Pragmatics expression 0% Reading 1% comprehension Alt/Non-verbal 3% 1% Memory 5% Auditory comprehension 7% Verbal expression 11% PF/Not related 0% Voice 0% Orientation 7% Speech 6% Attention 7% Problem solving 5% Executive functions 0% Swallowing 47% % Time in 1st block only; Long Stay Mid level communicators (Comp 4-5) Pragmatics 0% Alt/Non-verbal 0% Written expression 3% Reading comp 10% Memory 1% Verbal expression Auditory comp 0% 4% Voice PF/Not related 4% 0% Speech 4% Orientation 2% Attention 19% Problem solving 18% Executive functions 0% Swallowing 35% Complexity of Activities for Short, Medium, and Long Stays 60 50 40 30 20 10 0 Simple Mid Complex 1 block 5 blocks 8 blocks Trends for a Long Stay  Averaged 34.7 SLP sessions over 39.7 day LOS Patients had more:  R CVAs  Cortical lesions  Time in swallowing: 47% of 1st block  Time in attention (mid level group) Almost no time in executive function across LOS Discharge: home    Activities in the 1st block of therapy 70 60 50 40 30 20 10 0 Simple Mid Complex short stay, low short stay, mid medium stay, low medium stay, mid long stay, low long stay, mid How did these patients do? Short (1 block) Medium (5 blocks) Long (8 blocks) Mean increase motor FIM cognitive FIM 19.6 4.6 23.1 5.3 30.1 8.1 Discharge destination (%) home/community institution 81.6 18.4 60.0 40.0 88.2 11.8 Factors Associated with Success  A reminder of “success”:  Low-level communicators   Expression: increase in D FIM to > Level 4 Comprehension: increase in D FIM by 2 levels  Mid-level communicators  Comprehension: increase D FIM to > Level 6 Expression: increase D FIM to > Level 6 If the patient’s comprehension was 1 – 3 on admission they were more likely to be successful if  in the first 3 hours of SLP they spent time in:   Problem solving Executive function  and/or they:  stayed longer If the patient’s comprehension was 1 – 3 on admission they were less likely to be successful if  in the first 3 hours of SLP they spent time in:    Verbal expression Written expression and/or they:  were female  had a brainstem stroke  had a D FIM for bladder of 1 - 3 Success Rate  Admission comprehension 1–3  88 patients / 50% were successful If the patient’s comprehension was 1 – 3 and expression was 1 -3 they were more likely to be successful if  in the first 3 hours of SLP they spent time in:   Problem solving Executive function  and/or they:    stayed longer had a hemorrhagic stroke had higher A FIM Cognition and Verbal Expression* If the patient’s comprehension was 1 – 3 and expression was 1 -3 they were less likely to be successful if  in the first 3 hours of SLP they spent time in:  Reading comprehension  and/or they:  were female  had a D FIM for bladder of 1 – 3*  had a D FIM for bladder of 4 - 5 Success Rate  Admission comprehension 1 – 3 and expression 1 – 3  77 patients / 54.6% were successful If the patient’s comprehension was 4 – 5 on admission they were more likely to be successful if  in the first 3 hours of SLP they spent time in:  Problem solving  and/or they:  stayed longer  had higher A FIM Cognition, Memory*, or Comprehension* If the patient’s comprehension was 4 – 5 on admission they were less likely to be successful if  in the first 3 hours of SLP they spent time in:  Auditory comprehension  and/or they:  had higher A CSI  had a D FIM for bladder of 1 – 3 Success Rate  Admission comprehension 4–5  114 patients / 52% were successful If the patient’s comprehension was 4 – 5 and expression was 4 -5 they were more likely to be successful if  in the first 3 hours of SLP they spent time in:  Problem solving  and/or they:  were white  stayed longer  had a D FIM for bladder of 6-7  had higher A FIM Cognition or Expression If the patient’s comprehension was 4 – 5 and expression was 4 -5 they were less likely to be successful if  in the first 3 hours of SLP they spent time in:  Verbal expression  and/or they:  had a hemorrhagic stroke  stayed longer  had a higher A CSI  had higher A FIM Motor or Toilet Transfer*  were of race: other Success Rate  Admission comprehension 4– 5 and expression 4 - 5  75 patients / 52% were successful In Summary, during 1st therapy block Greater likelihood of success  Less likelihood of success  Complex activities Mid-level activities Problem solving, executive functioning Verbal expression, reading comprehension and written expression What this means for clinical practice  For patients with low linguistic ability on admission  Appear to benefit from high level tasks early in treatment  Tasks may not directly correspond to impairment area  May need more cueing/assistance to complete tasks initially Why might this be?  High level tasks involve critical thinking  mental flexibility  mental manipulation  integration of multiple components of information  creativity  Common Threads  Corresponds to results in other therapy disciplines   OT – home management tasks PT – gait and advanced gait Common Threads  Introducing complex tasks earlier in a length of stay despite the patient’s level of impairment is associated with better outcomes   integration of individual components vs. each component in isolation May require recruitment of more cognitive and linguistic skills that drive functional activity  Error detection, revision/repair, self-regulation Limitations in data analysis     Limitations of FIM as measurement tool Subjective and objective choices in creating homogenous groups Potential inconsistencies/inaccuracies in recording of treatment interventions Context in which the intervention was implemented was not captured Future research        Validity studies Interventions Correlation of findings with standardized test scores Initial evaluation time Impact of such a large % of time on swallowing Variation in site practice International comparisons of practice  New Zealand  CERICE Acknowledgements National Institute on Disability & Rehabilitation Research (Grant # H133B990005)  RW Brannon, MSPH, project officer  RRTC on Medical Rehabilitation Outcomes Boston University with subcontracts to:  ICOR (Salt Lake City, UT) & NRH-CHDR (Washington, DC) U.S. Army & Materiel Command (Cooperative Agreement Award # DAMD17-02-2-0032)  CR Miles & M Lopez, PhD project officers).  NRH Neuroscience Research Center National Blue Cross-Blue Shield Association Gerben DeJong, PhD Koen Putnam, PhD The many contributions of individual clinical sites & investigators

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