Mapping the Human Genome what does it mean for you

Human Genome Project Human Genome Project Til now, we’ve talked about proteins….. If proteins so special….. What we already know DNA: Deoxyribonucleic Acid DNA Structure: Building Blocks Functions? Nitrogen Bases Focus on 1 DNA strand DNA 2 strands! Rules Double Helix Base bonding important – 3 reasons How? Example on Board Reason 2. Stability Reason 3. Error Checking Bonding rules reduce errors Genes Genes So, this is what DNA is The challenge Step 1: Examine pieces of the genome Chromosomes Package for moving Spooling, twisting, coiling Spooling, twisting, coiling Why the X shape? DNA replication and Chromosome Arms The full human set 46 chromosomes 23 pairs Note X and Y Chromosomes Each chromosome type contains different info Traits on Different Chromosomes Alcohol processing Blood Type Eye Color Athletic performance? ‘premature’ alzheimers One chromosome at a time Now what? (Very simplified) Line up fragments Example Frag 1 First set: Second set Third set AAAC GTTT CTGTTTCA Frag 2 TGTTT CATCTA AAA Frag 3 CATCTA AAACT TCTA Working out on Board Line up fragments Put pieces back together What did the Human Genome Project do? How do you identify a gene? Where next? How different is our DNA? Why do this?