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					                                Genome Games

Introduction

Suitable for KS3/KS4 these games explore human genetics using familiar formats.
Games similar to Pictionary, Taboo and Consequences introduce students to a
variety of issues. Students will be encouraged to think about the ethical and
social issues relating to the rapidly moving field of human genetics and the
possible impact it may have on medicine, healthcare and individuals rights.

Each game will give students the opportunity to discover more about the topic at
hand, discuss related issues, form their own opinions and communicate what they
think to other members of the group. The game activities focus on genetic
terminology, ethical and social issues relating to the developments in human
genetics.

The resources are very flexible. They can be used in Citizenship or Science
lessons. They can be used as starter or plenary activities. Each activity can be
used on its own, or together in any combination. Some games can be used as a
whole class activity, while other games work well with small groups. How long
each game or session lasts is also flexible and can be adapted for any class.


Contents

Page                          Content

1                             Intro/contents page
2-8                           Glossary
9                             Illustrate introduction
10                            Illustrate KS3 cards
11-12                         Illustrate KS4 cards
13                            Taboo Introduction
14-16                         Taboo KS3 cards
17-22                         Taboo KS4 cards
23                            Pairs introduction
24-26                         Pairs cards
27                            Cloned animals
28                            Missing words introduction
29-31                         Missing words sheets
32                            Completed headlines
33-38                         Missing words extra information




                             www.at-bristol.org.uk/cz
The Glossary
This provides a useful reference tool for both students and staff and in
particular is designed to include all the terms used in Illustrate and Taboo.




                             www.at-bristol.org.uk/cz
                                                     Glossary




                            Underlined words can be found elsewhere in the glossary

                           Where you see this symbol, follow the link for more information



Allele: One member of a pair or series of genes that occupy a specific position on a specific chromosome.
(http://dictionary.reference.com/)

Amino acid: Any of a class of 20 molecules that are combined to form proteins in living things. The sequence
of amino acids in a protein and hence protein function are determined by the genetic code.
(http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)

Aryan race: A member of the Indo-European-speaking people first living in Iran and later entering India and
conquering the people living there. (http://www.wordcentral.com/)

In Nazism and neo-Nazism, a non-Jewish Caucasian, especially one of Nordic type, supposed to be part of a
master race. (http://dictionary.reference.com/)

See also Eugenics

Asexual reproduction: Reproduction in which an organism produces one or more clones of itself, such as by
fission or budding. (http://biotech.icmb.utexas.edu/search/dict-search.html)

Biotechnology: The use of microorganisms, such as bacteria or yeasts, or biological substances, such as
enzymes, to perform specific industrial or manufacturing processes. Applications include the production of
certain drugs, synthetic hormones, and bulk foodstuffs as well as the bioconversion of organic waste and the
use of genetically altered bacteria in the cleanup of oil spills. (http://dictionary.reference.com/)

Blastocyst: See Blastula

Blastula: An early embryo typically having the form of a hollow fluid-filled rounded cavity bounded by a single
layer of cells. (http://www.wordcentral.com/)

Cancer: Diseases in which abnormal cells divide and grow unchecked. Cancer can spread from its original site
to other parts of the body and can also be fatal if not treated adequately. (www.genome.gov/glossary.cfm)

Carbon Copy: Also known as CC, Carbon copy was the first cloned cat. She was cloned by a team at Texas
A&M University in February 2002.
   (http://www.bbc.co.uk/science/genes/gene_safari/clone_zone/pet02.shtml)

Carrier: An individual that carries one gene for a particular recessive trait. A carrier does not express the trait
but, when mated with another carrier, can produce offspring that do. (http://dictionary.reference.com/)

Cells: One of the tiny units that are the basic building blocks of living things, that carry on the basic functions of
life either alone or in groups, and that include a nucleus and are surrounded by a membrane.
(http://www.wordcentral.com/)

Chromosomes: One of the threadlike "packages" of genes and other DNA in the nucleus of a cell. Different
kinds of organisms have different numbers of chromosomes. Humans have 23 pairs of chromosomes, 46 in all:
44 autosomes and two sex chromosomes. Each parent contributes one chromosome to each pair, so children
get half of their chromosomes from their mothers and half from their fathers. (www.genome.gov/glossary.cfm)



                                            www.at-bristol.org.uk/cz
                                                  Glossary




Clones: An exact copy made of biological material such as a DNA segment (e.g., a gene or other region), a
whole cell, or a complete organism. (http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)

Cloning: Using specialized DNA technology to produce multiple, exact copies of a single gene or other
segment of DNA to obtain enough material for further study.
(http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)

CopyCat: See Carbon Copy

Cryogenesis: The science concerned with the production and effects of very low temperatures.
(http://cancerweb.ncl.ac.uk/omd/index.html)

Designer babies: Popular press term for selecting which babies will be born on the basis of their genetics.
   (http://www.bbc.co.uk/science/genes/gene_safari/wild_west/designer_babies.shtml)

Detective: A person, usually a member of a police force, who investigates crimes and obtains evidence or
information. (http://dictionary.reference.com/)

Double helix: The coiled structure of double-stranded DNA in which strands linked by hydrogen bonds form a
spiral configuration, with the two strands oriented in opposite directions. (http://dictionary.reference.com/)

DNA: Deoxyribonucleic acid. The chemical inside the nucleus of a cell that carries the genetic instructions for
making living organisms. (www.genome.gov/glossary.cfm)

DNA bank: A service that stores DNA extracted from blood samples or other human tissue.
(http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)

DNA database: See DNA bank

DNA detectives: See Detective

DNA fingerprint: An individual's unique sequence of DNA base pairs, determined by exposing a sample of the
person's DNA to molecular probes. DNA fingerprints are often used as evidence in criminal law cases. Also
called genetic fingerprint. (http://dictionary.reference.com/)

DNA fingerprinting: A method of identification (as for forensic purposes) by determining the unique pattern of
a person's DNA. (http://www.wordcentral.com/)

See also DNA fingerprint

Dominant: A gene that almost always results in a specific physical characteristic, for example, a disease, even
though the patient's genome possesses only one copy. With a dominant gene, the chance of passing on the
gene (and therefore the disease) to children is 50-50 in each pregnancy. (www.genome.gov/glossary.cfm)

Dolly: Dolly was the first mammal to be cloned from an adult cell. She was created by scientists at the Roslin
Institute in Edinburgh in 1996.
    (http://www.bbc.co.uk/science/genes/gene_safari/factfiles/dolly.html)

Egg cell: A female gamete; an ovum. (http://dictionary.reference.com/)

See also Gamete

Embryo: An organism at any time before full development, birth, or hatching. (http://dictionary.reference.com/)
                                          www.at-bristol.org.uk/cz
                                                   Glossary




Eugenics: The study of improving a species by artificial selection; usually refers to the selective breeding of
humans. (http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)

Evolution: Change in the genetic composition of a population during successive generations, as a result of
natural selection acting on the genetic variation among individuals, and resulting in the development of new
species. (http://dictionary.reference.com/)

Extinct species/Extinction: The death of an entire species. (http://biotech.icmb.utexas.edu/search/dict-
search.html)

Forensic: Relating to the use of science or technology in the investigation and establishment of facts or
evidence in a court of law. (http://dictionary.reference.com/)

Forensic evidence: See Forensic

Forensic science: See Forensic

Frankenstein: The fictional Swiss scientist who was the protagonist in a gothic novel by Mary Wollstonecraft
Shelley; he created a monster from parts of corpses. (http://dictionary.reference.com/)

Fraternal twin: Either of two twins who developed from two separate fertilized eggs.
(http://dictionary.reference.com/)

Gamete: A mature sex cell that usually has half of the normal number of chromosomes and is capable of
uniting with a gamete of the opposite sex to begin the formation of a new individual.
(http://www.wordcentral.com/)

Genes: The functional and physical unit of heredity passed from parent to offspring. Genes are pieces of DNA,
and most genes contain the information for making a specific protein. (www.genome.gov/glossary.cfm)

Gene pool: The collective genetic information contained within a population of sexually reproducing
organisms. (http://dictionary.reference.com/)

Gene therapy: An experimental procedure aimed at replacing, manipulating, or supplementing nonfunctional
or misfunctioning genes with healthy genes. (http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)

Genetic counselling: A short-term educational counselling process for individuals and families who have a
genetic disease or who are at risk for such a disease. Genetic counselling provides patients with information
about their condition and helps them make informed decisions. (www.genome.gov/glossary.cfm)

Genetic engineering: Altering the genetic material of cells or organisms to enable them to make new
substances or perform new functions. (http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)

Genetic testing for disease: Analysing an individual's genetic material to determine predisposition to a
particular health condition or to confirm a diagnosis of genetic disease.
(http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)

Genomes: An organism's genetic material. (http://dictionary.reference.com/)

Genotype: The genetic makeup, as distinguished from the physical appearance, of an organism or a group of
organisms. (http://dictionary.reference.com/)



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                                                       Glossary




Gregor Mendel: An Austrian monk and botanist who lived from 1822 to 1884; his breeding experiments on
garden peas and subsequent formulation of the laws of heredity formed the basis for the field of genetics.
(http://biotech.icmb.utexas.edu/search/dict-search.html)

Hetrozygote: Possessing two different forms of a particular gene, one inherited from each parent.
(www.genome.gov/glossary.cfm)

Homozygote: Possessing two identical forms of a particular gene, one inherited from each parent.
(www.genome.gov/glossary.cfm)

Human Genome Project: An international research effort to map and identify the role of all genes in the
human genome. (http://dictionary.reference.com/)

Hybrid: The offspring of genetically dissimilar parents or stock, especially the offspring produced by breeding
plants or animals of different varieties, species, or races. (http://dictionary.reference.com/)

Identical twins: Twins derived from the same fertilized ovum that at an early stage of development becomes
separated into independently growing cell aggregations, giving rise to two individuals of the same sex, identical
genetic makeup, and closely similar appearance. (http://dictionary.reference.com/)

Immortality: Living or lasting forever. (http://www.wordcentral.com/)

Implantation: The process by which a fertilized egg implants in the uterine lining.
(http://dictionary.reference.com/)

Inheritance: The process of genetic transmission of characteristics from parents to offspring.
(http://dictionary.reference.com/)

IVF: In vitro fertilisation. (Literally, "in glass") Fertilization outside the body in a laboratory; the term "test tube
baby" is inaccurate since fertilization occurs in a small circular dish, not a test tube.
(http://biotech.icmb.utexas.edu/search/dict-search.html)

Karyotype: A photomicrograph of an individual's chromosomes arranged in a standard format showing the
number, size, and shape of each chromosome type; used in low-resolution physical mapping to correlate gross
chromosomal abnormalities with the characteristics of specific diseases.
(http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)

Locus: The position that a given gene occupies on a chromosome. (http://dictionary.reference.com/)

Microscope: A piece of laboratory equipment that is used to magnify small things that are too small to be seen
by the naked eye, or too small for the details to be seen by the naked eye, so that their finer details can be
seen and studied. (http://biotech.icmb.utexas.edu/search/dict-search.html)

Mutation: A permanent structural alteration in DNA. In most cases, DNA changes either have no effect or
cause harm, but occasionally a mutation can improve an organism's chance of surviving and passing the
beneficial change on to its descendants. (www.genome.gov/glossary.cfm)

Nucleus: The central cell structure that houses the chromosomes. (www.genome.gov/glossary.cfm)

Petri dish: A shallow circular dish with a loose-fitting cover, used to culture bacteria or other microorganisms.
(http://dictionary.reference.com/)



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                                                    Glossary




Pharm animals: Popular press term for animals that have been genetically engineered to produce medicines
Therapeutic cloning: Can create cloned human cells, but not whole embryos beyond the 14-day
in their milk or urine. (http://www.bbc.co.uk/science/genes/gene_safari/pharm/a_pharming.shtml) stage. May
be used to better understand human development, provide resources for stem cell therapy research, and
Pharming: Popular press term for the production of genetically engineered animals that produce medicines in
develop new treatments for disease.
their milk or urine. (http://www.bbc.co.uk/science/genes/gene_safari/pharm/a_pharming.shtml)
    (http://www.mrc.ac.uk/pdf_therapeutic_cloning.pdf)
Phenotype: The relatingcharacteristics of a plant or animal that result from the combined effects of of a genesor
Transgenic: Of, visible to, or being an organism whose genome has been altered by the transfer the gene
and the environment. (http://www.wordcentral.com/)
genes from another species or breed. (http://dictionary.reference.com/)
Protein: A large moleculeTransgenic. one or more chains of amino acids in a specific order; the order is
Transgenic animal: See composed of
determined by the base sequence of nucleotides in the gene that codes for the protein. Proteins are required
for the structure, function, andan organism, the body's cells,characteristic organs; and in nature, as has unique
Wildtype: The typical form of regulation of strain, gene, or tissues, and as it occurs each protein
functions. Examples are hormones, enzymes, and antibodies. breeding. (http://dictionary.reference.com/)
distinguished from mutant forms that may result from selective
(http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)
Xenotransplantation: See Xenograft
Recessive: A gene which will be expressed only if there are 2 identical copies or, for a male, if one copy is
present on the X chromosome. (http://www.ornl.gov/sci/techresources/Human_Genome/glossary/) organism of
Xenograft: Tissue or organs from an individual of one species transplanted into or grafted onto an
another species, genus, or family. A common example is the use of pig heart valves in humans.
Reproductive cloning: making a full living copy of an organism. (http://dictionary.reference.com/)
(http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)
RNA: Ribonucleic acid. A chemical found in the nucleus and cytoplasm of cells; it plays an important role in
protein synthesis and other chemical activities of the cell. The structure of RNA is similar to that of DNA.
(http://www.ornl.gov/sci/techresources/Human_Genome/glossary/)

Saviour siblings: Popular press term for embryos selected to be born to help save a sibling suffering from a
particular disorder.
    (http://www.bbc.co.uk/science/genes/gene_safari/wild_west/designer_babies.shtml)

Selective breeding: Combining the desirable traits of at least two genotypes, in order to breed new varieties.
(http://www.bbc.co.uk/genes/)

Spare organs: In the future, it may be possible to create spare organs from stem cells for replacement in the
case of damage or disease.
(http://www.bbc.co.uk/science/genes/gene_safari/clone_zone/human_cloning04.shtml)

Sperm: A reproductive cell produced by the male of an animal species which, when united with an egg (of the
same species), results in conception and the development of an embryo.
(http://biotech.icmb.utexas.edu/search/dict-search.html)

Stem cells: An undifferentiated cell whose daughter cells may differentiate into other cell types.
(http://dictionary.reference.com/)

Test tube: A clear, cylindrical glass tube usually open at one end and rounded at the other, used in laboratory
experimentation. (http://dictionary.reference.com/)

Test tube babies: Conceived by or developed from fertilization in laboratory apparatus or by artificial
insemination. (http://dictionary.reference.com/)

The term "test tube baby" is inaccurate since fertilization occurs in a small circular dish, not a test tube.
(http://biotech.icmb.utexas.edu/search/dict-search.html)




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Illustrate
In this game pupils get the opportunity to express their views visually. The
players try to guess various words, phrases or biological techniques by drawing
clues for each other. This game is an alternative method of expressing opinions
and prompts discussion through images.

Resources:      Glossary
                Illustrate cards

Format:         2-4 players as individuals or in teams can play this game. There are
                four categories on the cards, each represented by a symbol. Pupils
                can choose the category for the other players/team to draw:


      Person/Animal
      Object

      Process/Technique

 ?     Difficult

Players take it in turn to draw for their own team members. The drawer has one
minute to sketch clues to their team but may not speak at anytime. If the team
guess correctly within the time limit they win a point. A point is won if the



                                   www.at-bristol.org.uk/cz
    team successfully guesses what the image is. The group should be encouraged to
    discuss images drawn and conceptual differences between individual players.




    Illustr¦e                    Illustr¦e                       Illustr¦e
    Person/Anima                     Dolly the                     Extinct
          l                              Sheep                        Species
        Object                        Nucleus                     Test Tube
    Process/Techn                     Cloning                       Biology
         ique

      Difficult                          Cancer                     Immortalit
?                            ?                              ?
                                                                        y


    Illustr¦e                    Illustr¦e                       Illustr¦e
     Scientist                      Spiderman                      Identical
                                                                        Twins
        Embryo                    Chromosome                          Cells
                                              s
                                 www.at-bristol.org.uk/cz
           IVF                     Chemistry                        Physics
    Illustr¦e             Illustr¦e                      Illustr¦e
      Clones                Frankenste                 Test Tube
                                   in                       Babies
      Spare                    Genes                      DNA
       Organs
        Sexual
      Reproduction
                                 Genetic
                                Engineering
                                                          Freezing

      Designer                Inheritanc                  Environmen
       Babies                      e                          t
? Illustr¦e           ? Illustr¦e                    ? Illustr¦e
    Person/Anim                 Pharm                    Saviour
          al                     Animals                   Siblings
      Object                   Nucleus                    Genes

    Process/Techn
         ique
                             Implantati                 Inheritanc
                                  on                          e
     Difficult                     Asexual                Evolution
                                Reproduction

?                     ?                              ?
    Illustr¦e             Illustr¦e                      Illustr¦e
    Scientist                 Supermen                  Test Tube
                                                             Babies

       Sperm                   Genomes                 Petri Dish

    Xenotransplant
         ation
                                    IVF                  Pharming
                          www.at-bristol.org.uk/cz

       Future                 Extinction                   Mutation
    Illustr¦e             Illustr¦e                      Illustr¦e
       Gregor
        Mendel
                               Lab Rats                  Copycat

    Test Tube               Homozygote                 Heterozygo
                                                              te
     Reproductive
        Cloning                 Selective
                                  Breeding
                                                          Therapeutic
                                                             Cloning

      Genotype                 Phenotype                   Playing
                                                             God
? Illustr¦e           ? Illustr¦e                    ? Illustr¦e
 Person/Anim          Aryan Race                    Clones
       al
 Object               Blastocyst                    Chromosome
                                                            s
 Process/Techn
      ique
                       Cloning                       Cryogenesi
                                                              s
     Difficult                    Cancer                  Immortalit
                                                              y
?                     ?                              ?
    Illustr¦e             Illustr¦e                      Illustr¦e
     Designer                   DNA                       Dolly
       Babies                 Detectives
       DNA                  Microscope                  Egg Cell

         DNA
     Fingerprinting
                                Forensic
                                 Science
                                                           Gene
                                                           Therapy
      Dominant                 Recessive                   Forensic
                                                           Evidence
?                     ?   www.at-bristol.org.uk/cz
                                                     ?
    Illustr¦e                      Illustr¦e                      Illustr¦e
       Extinct                       Frankenste                   Identical
        Species                             in                         Twins
        Embryo                          Spare                       Cells
                                         Organs
        Genetic
       Counselling
                                          Genetic
                                         Engineering
                                                                   Genetic Testing for
                                                                          Disease


        Human Genome                      Transgenic
          Project
                                                                    Stem Cells
    Taboo                                  Animals

?                              ?                              ?
    The object of this game is to successfully describe words – without actually
    using the word itself! The players get the opportunity to learn new words or
    phrases and improve understanding by explaining to others what they think the
    word is. Everyone in the group can discover, discuss and debate each other’s
    definitions.

    Resources:   Glossary
                 Taboo cards
                 Bag or hat


    Format:
    This can be played with small groups of 2-6 playing in teams. They have one
    minute to describe as many words as possible to their team, without using the
    word itself. The first player removes a word from the bag/hat and describes it
    to their team. As soon as the team have guessed the word, the player moves onto
    the next one until the minute is up. Used cards do not go back in the bag. The
    next team then has a minute to define words to their team. Play returns to first
    team and continues until all the words have been used. The team with the most
    words guessed wins.




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  Biology                              Clones


                                      Dolly the
Chemistry
                                       Sheep


Frankenstein



   Parents


 Test Tube
           www.at-bristol.org.uk/cz
  Babies
                                        Physics


  Extinct                               Designer
  Species                                Babies


  Future                                 Lab
                                         Rats


 Scientist                              Mutation



   DNA                                    IVF


                                        Spare
  Embryo                                Organs


Chromosomes                        Immortality
             www.at-bristol.org.uk/cz
Inheritance                             Cells

 Nucleus
                                        Genes


 Genetic
Engineering                            Test Tube


  Cloning
                                        Cancer



 Freezing
                                  Environment


                                    Asexual
Dominan                            Reproduct
   t                                  ion
Forensi     www.at-bristol.org.uk/cz

   c                                   Mutati
  Aryan
                                     Future
   Race
  DNA
Detectiv                         Transgen
   es                                ic
                                  Animals
                                 Identic
Frankenst                            al
   ein                             Twins
Saviour                              Superme
Sibling                                 n
    s
Designer                          Pharm
 Babies                          Animals

 Extinc
                                     Phenoty
    t
                                        pe
 Specie   www.at-bristol.org.uk/cz
 Gregor                                Lab
 Mendel                               Rats

 Scient                              Blastoc
   ist                                 yst

                                       DNA
Recessi                              Databas
ve                                      e
                                      Spare
 Embryo                              Organs


 CopyCa                                Egg
    t                                 Cell

Chromosome                       Extincti
    s                               on
          www.at-bristol.org.uk/cz
  Human
  Genome                                Stem
 Project                               Cells

  Petri                               Playing
   Dish                                 God

Hetrozygo                              Sperm
te

                                     DNA
Cryogene                         Fingerprin
  sis                               ting

Genomes                           Evoluti
                                     on
                                      Forensi
Homozygot                                c
    e
                                      Science

                                   Genetic
                                  Counsell
           www.at-bristol.org.uk/cz
         Gene
        Therapy

          Genetic
        Testing for
          Disease


         Genotyp
            e
         Selecti
            ve
         Breedin
             g
         Genetic                                    Reproduct
        Engineeri                                      ive
            ng                                       cloning
                                                        Xeno-
        Inherita                                     transplant
          nce                                           ation

Pairs
This is a   fun visual game where you match animals to their clones. The aim is to
introduce   students to the issues surrounding animal cloning. You could use this
game as a   stimulus for further discussion, asking the students to respond to the
questions   as they are revealed and leading, if desired to wider discussions
about the   issues surrounding cloning.


                               www.at-bristol.org.uk/cz
Resources   Cloned animal cards
            Cloned animal information

Format:     These resources can either be used for Pairs or Snap.

Pairs is a memory game where the cards are turned face down, and players take
turns to turn two over. If the images match they win the pair and then have to
open up the question to the rest of the group for discussion. If not they are
returned face down and the next player has their turn. The pictures on the cards
are all animals that have been successfully cloned.




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Would you have…                              …a cloned pet?




 Are these cow                               …unnatural?
    clones…




                  www.at-bristol.org.uk/cz
Is there any animal…             …we should never clone?
                                           Why?




 Would cloned mice…                …act and behave alike?




Is Dolly the sheep…
                  www.at-bristol.org.uk/cz …a scientific
                                            achievement?
                     Cloned animal information




                                  Tadpole
                      First animal to be cloned. 1959.


                                  Sheep
Are identical twins… cloned mammal from …unique? 1996.
  Dolly was the first successfully      an adult cell.


                                  Cows
 Cows, the second successful adult-animal clones, were created in Japan in
                                  1998.


                                  Mice
     Cumulina was the first born mouse clone, born in Hawaii in 1998.


                                   Goats
                Goats were first cloned in Canada in 1999.


                                    Pigs
    Five healthy pigs were born to a British company in America in 2000.


                                     Cat
                 Cc was the first cloned cat, born in 2001.


                                  Rabbits
              The first cloned rabbits born in France in 2002.




                           www.at-bristol.org.uk/cz
Missing words
This game has headlines taken from popular British press news stories on
genetics. Pupils can work their way through and fill in what they think the
missing word may be.

Resources:   Missing words template
             Missing words answers
             Extra information

This is an excellent resource for providing a background to the possibilities of
cloning and potential issues surrounding this technology. This resource can be
used to both inform the students and lead to further discussion around the
issues raised.




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                    Missing Words




Nine lives just the start for tomorrow’s _______
Times 17/04/04




Britain first to _______ human cloning
Guardian 19/04/01




NHS to safeguard against ‘genetic __________’
Guardian 24/06/03




________________ to be outlawed
Guardian 19/04/01




Estonia sells its _________ pool
Guardian 09/11/00




Taking ________ by stealth ‘should be outlawed’
Guardian 22/05/02




Children treated with __________ cells.
BBC News 17/02/04




                    www.at-bristol.org.uk/cz
                          Missing Words




Genetic _________ risk creating a new underclass
Guardian 28/09/00




UK's first 'designer baby' born to help __________
Independent 19/06/03




              Dolly boffin backs _________       of ___________
The Sun 19/02/04




_________________ funds ‘designer baby’
Femail 22/03/04




Baby _______ selection ruled out
Femail news 12/11/03




Carbon kitty's $__________ price tag
BBC News 28/04/04




                           www.at-bristol.org.uk/cz
                    Missing Words




____________ cheats seek genetic boost
BBC NEWS 16/02/04




____________ ‘should see gene tests’
BBC NEWS 30/01/04




____________ aid to genetic study
BBC NEWS 17/12/03




Scientists clone 30 ____________ embryos
BBC NEWS 12/02/04




Test tube ______________ created
BBC NEWS 29/01/02




Cloned sheep Dolly has ______________
BBC NEWS 04/01/02




Body parts cloning 'to go ___________’
BBC NEWS 30/07/00




                    www.at-bristol.org.uk/cz
                                         Completed headlines




Nine lives just the start for tomorrow’s cats                      Times 17/04/04

Britain first to ban human cloning                                        Guardian 19/04/01

NHS to safeguard against ‘genetic underclass’                             Guardian 24/06/03

Human cloning to be outlawed                                       Guardian 19/04/01

Estonia sells its gene pool                                               Guardian 09/11/00

Taking DNA by stealth ‘should be outlawed’                         Guardian 22/05/02

Children treated with stem cells                                          BBC News 17/02/04

Genetic test risk creating a new underclass                        Guardian 28/09/00

UK's first 'designer baby' born to help sick brother               Independent 19/06/03

Dolly boffin backs cloning of babies                               The Sun 19/02/04

Taxpayer funds ‘designer baby’                                            Femail 22/03/04

Baby sex selection ruled out                                       Femail news 12/11/03

Carbon kitty's $50,000 price tag                                          BBC News 28/04/04

Athlete cheats seek genetic boost                                  BBC NEWS 16/02/04

Insurers ‘should see gene tests’                                          BBC NEWS 30/01/04

Robotic aid to genetic study                                       BBC NEWS 17/12/03

Scientists clone 30 human embryos                                  BBC NEWS 12/02/04

Test tube kidneys created                                                 BBC NEWS 29/01/02

Cloned sheep Dolly has arthritis                                          BBC NEWS 04/01/02

Body parts cloning 'to go ahead'                                          BBC NEWS 30/07/00




                                        www.at-bristol.org.uk/cz
                                   Missing words extra information




Nine lives just the start for tomorrow’s cats
Cats really can have nine lives. Or ten or 11, or however many their owners choose, after a
Californian firm began offering the world’s first cat cloning service for $50,000 (£27,700) per
animal. Nine cloned kittens are expected by November.
                                                                                 Times 17/04/04

Britain first to ban human cloning
Human cloning will be banned in Britain - the first country to do so - in a move calculated to
allay ethical fears about how rapidly genetic science is advancing, the government
announced today.
                                                                             Guardian 19/04/01

NHS to safeguard against ‘genetic underclass’
The NHS is to have a crucial role in ensuring that advances in genetic testing do not lead to
the neglect of an "unwell and uninsurable" underclass, the health secretary, John Reid,
announced today.
                                                                           Guardian 24/06/03

Human cloning to be outlawed
The government is drawing up legislation to outlaw human reproductive cloning in an
attempt to reassure the public that its plans for fast expansion of genetic technology in the
NHS will not breach ethical beliefs.
                                                                              Guardian 19/04/01

Estonia sells its gene pool
Do you happen to have a few hundred million pounds ready? Do you want to buy a
population of 1.3 million people? If so, contact the "Eesti Geenikeskus", the Estonian
Genome Foundation.
                                                                            Guardian 09/11/00

Taking DNA by stealth ‘should be outlawed’
Secretly taking DNA samples to establish blood relationships or to obtain other highly
personal information should be made a criminal offence, Britain's genetic watchdog said
yesterday.
                                                                          Guardian 22/05/02
Children treated with stem cells
Researchers in the US say they have been using stem cells to successfully treat genetic
diseases in children. The doctors told a conference that cells taken from umbilical cord blood
can turn into healthy heart cells, for instance, and repair damaged tissue. The research
suggests many childhood disorders such as leukaemia can be treated in this method.
BBC News 17/02/04




                                        www.at-bristol.org.uk/cz
                                   Missing words extra information




Genetic test risk creating a new underclass
The United States equal employment opportunities commissioner, Paul Miller, has called for
tougher safeguards for workers against genetic discrimination after it emerged that hundreds
of people have already lost their jobs or insurance protection as a direct result of advances
in genetic screening.
                                                                             Guardian 28/09/00

UK's first 'designer baby' born to help sick brother
Britain's first genetic "designer" baby has been born to a couple who are desperate to cure
their young son who has a rare form of anaemia.
                                                                        Independent 19/06/03


Dolly boffin backs cloning of babies
Prof says it will help beat disorders. The scientist who led the team behind Dolly the sheep
yesterday said he supports cloning humans.
                                                                            The Sun 19/02/04
Taxpayer funds ‘designer baby’
The health service could pay up to £20,000 to create a "designer baby" to save the life of a
child with a rare blood disorder.
The decision has led to ethical concern over taxpayer's cash being used to fund a treatment
which involves both IVF and embryo screening.
Femail 22/03/04

Baby sex selection ruled out
Moves to prevent couples being allowed to choose the sex of their baby for reasons other
than medical concerns have been welcomed by doctors, fertility experts and ethical
watchdogs.
                                                                     Femail news 12/11/03

Carbon kitty's $50,000 price tag
Cats can now have more than nine lives thanks to a Californian company that is the first US
firm to go commercial and offer the public a pet cloning service.
                                                                     BBC News 28/04/04


Athlete cheats seek genetic boost
The prospect that athletes will soon try to enhance their bodies with gene technology is
raised by the results of a new study to boost muscles in rats.
The scientist behind the research says his intention was to find new ways of treating muscle
wasting diseases.
                                                                         BBC NEWS 16/02/04



                                        www.at-bristol.org.uk/cz
                                   Missing words extra information




Insurers ‘should see gene tests’
 The results of tests for genetic diseases should be made available
    to insurance firms, say doctors. Writing in the Lancet medical
  journal, the University of East Anglia experts say it is unlikely
      the findings would be misused to treat customers unfairly.
                                                     BBC NEWS 30/01/04
Robotic aid to genetic study
Two robots have been introduced to a research project that has been tracking the health of
Bristol children. The robots - named the Germinator and the Robobanker - will help
researchers improve their understanding of human molecular biology. The Germinator
grows tissue to produce DNA while the Robobanker extracts samples for analysis.
                                                                      BBC NEWS 17/12/03
Scientists clone 30 human embryos
South Korean scientists have cloned 30 human embryos to obtain cells they hope could one
day be used to treat disease. Seoul National University's Woo Suk Hwang, and colleagues,
took the genetic material from normal cells in women donors and combined it with their
eggs.
                                                                     BBC NEWS 12/02/04
Test tube kidneys created
Scientists have used cloning technology to create fully functioning kidneys in the laboratory.
They hope the breakthrough could one day help to solve the problem of a severe shortage
of donor organs for transplant. The organs were created from cells taken from a cow's ear.
                                                                         BBC NEWS 29/01/02
Cloned sheep Dolly has arthritis
Dolly the cloned sheep has arthritis according to one of the scientists involved in her
creation. Professor Ian Wilmut, a member of the team at the Roslin Institute in Edinburgh,
said the condition may have arisen because of genetic defects caused by the cloning
process.
                                                                          BBC NEWS 04/01/02
Body parts cloning 'to go ahead'
The government is to give the go-ahead to growing "spare body parts", from human
embryos, it has been reported. Ministers are said to be preparing to make cloning of tissue
from embryos legal for medical purposes, now that a report into the ethical and scientific
implications of the issue has been completed.
BBC NEWS 30/07/00




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