QUEEN S C KINGSTON HOSPITALS C CIHR Fetal Movement

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					                                    PUBLIC FORUM

                 “FROM DISCOVERY TO PRACTICE TO YOU:
                    HEALTH RESEARCH IN KINGSTON”

                      TUESDAY, 15 NOVEMBER 2005
                           4:00 p.m. – 7:00 p.m.
                  MEMORIAL HALL, KINGSTON CITY HALL

                  CIHR FIFTH ANNIVERSARY CELEBRATION


4:00-4:10 p.m.      Welcome/Introductory Remarks                                    Dr. James F. Brien
                                                                                    Dr. R. Kerry Rowe
                                                                                Dr. Samuel K. Ludwin

4:10-4:30 p.m.      CIHR: Supporting Research,                                       Dr. Mark A. Bisby
                    From Discovery to Practice

                    CIHR is the federal government’s agency for the support of health research at
                    universities and hospitals across Canada. Health research provides new treatments,
                    helps improve the efficiency of the health care system, and, by telling us what keeps
                    people healthy and makes others sick, helps governments develop policies for
                    health maintenance and disease prevention

4:30-5:00 p.m.      Hypertension:                                               Dr. Michael A. Adams
                    Discovery of Causes and Treatment

                    One in every 4 Canadians has high blood pressure (hypertension), and yet even after
                    it is discovered it is not effectively treated. Treatment failure is a much too frequent
                    occurrence which creates serious health problems since hypertension markedly
                    increases the risk of these people ending up with serious cardiovascular diseases.
                    Obviously, there is a continuing need to find ways to better treat these patients.
                    Accordingly, at the experimental level, our research goal is to find novel therapeutic
                    approaches to permanently reverse high blood pressure, in particular, targeting the
                    development of therapies that can induce specific changes in the kidney that “reset”
                    the blood pressure to lower levels.

5:00-5:30 p.m.      Keep it Moving: Human Mobility,                              Dr. Timothy Bryant &
                    Challenges and Treatment                                      Ms. Margaret Alden

                    In 1998, Queen’s University and Kingston General Hospital (KGH) took the first
                    steps toward improving the lives of Canadians through restored mobility. Building
                    on nearly 40 years of leadership in biomedical engineering, computer and
                    information sciences, health sciences, surgery and medicine, the Human Mobility
                    Research Centre is a North American leader for its pioneering advances in the
                    development of new treatments and therapies that translate into exceptional
                    opportunities for patient care.
5:30-6:00 p.m.   Practice Research in Nursing: Rural Health                 Dr. Jennifer Medves

                 Practice Research in Nursing is concerned with research evidence to support every
                 day care nursing and health care. Practice Research involves clinical bedside
                 practice as well as research to support planning and delivering programmes of care
                 to communities and populations.

6:00-6:05 p.m.   Concluding Remarks                                            Dr. James F. Brien

6:05-7:00 p.m.   Reception and Viewing of Posters                                              All
                 of Research Groups
                     THURSDAY, 17 NOVEMBER 2005

                          7:00 p.m. – 9:00 p.m.
                     CHAPTERS COMMUNITY ROOM
                            2376 Princess St.

           “QUALITY LIVING THROUGH HEALTHY LIFESTYLES”


7:00-7:10 p.m.   Welcome/Introductory Remarks                                    Dr. James F. Brien

7:10-7:40 p.m.   Obesity: The Canadian Context                                     Dr. Robert Ross/
                                                                                    Dr. Ian Janssen

7:40-8:10 p.m.   Identifying Children at Risk for                                 Dr. Wendy Craig
                 Involvement in Bullying

                 The goals of this presentation are to 1) identify individual, family, and peer factors
                 that are related to bullying and victimization; 2) discuss the developmental
                 pathways and outcomes for children involved in bullying problems; and 3) review
                 successful strategies for intervening in bullying problems.

8:10-8:30 p.m.   Nutrition Break

8:30-9:00 p.m.   How Chemicals Cause Lung Damage                            Dr. Thomas E. Massey

                 Both environmental chemicals and some therapeutic drugs have the ability to cause
                 toxicity to the lung. We are examining the mechanisms by which these chemicals
                 exert their toxic effects, with the aim of developing ways to prevent or halt the lung
                 damage.

9:00-9:05 p.m.   Concluding Remarks                                              Dr. James F. Brien
                          FRIDAY, 18 NOVEMBER 2005

                               1:00 p.m. – 3:00 p.m.
                        KFL&A PUBLIC HEALTH UNIT
                        221 Portsmouth Ave., Auditorium B

                 “HEALTHY PREGNANCIES/HEALTHY BABIES”


1:00-1:10 p.m.      Welcome/Introductory Remarks                                 Dr. James F. Brien

1:10-1:40 p.m.      Fetal Alcohol Spectrum Disorders                     Dr. James N. Reynolds &
                                                                           Ms. Courtney R. Green

                    A brief overview of Fetal Alcohol Spectrum Disorders will be followed by a
                    discussion of emerging concepts for new diagnostic tools and therapeutic
                    interventions in the FASD population.

1:40-2:10 p.m       Puzzling Association between                      Ms. Shannon A. Bainbridge
                    Smoking and Pre- Eclampsia

                    Smoking throughout pregnancy is associated with several negative outcomes.
                    Interestingly however, cigarette smoking reduces a woman’s risk of developing pre-
                    eclampsia. Ongoing CIHR funded studies are examining whether carbon monoxide
                    may be the compound responsible for this reduced risk.

2:10-2:30 p.m.      Nutrition Break

2:30-3:00 p.m.      Drugs, Chemicals and Fetal                              Dr. Louise M. Winn &
                    Development                                                   Ms. Joanne Wan

                    When a pregnant woman is exposed to drugs or environmental chemicals, her
                    unborn child may be at increased risk for developmental toxicity. This
                    presentation will discuss ongoing work investigating ways in which this
                    toxicity may occur.

3:00-3:05 p.m.      Concluding Remarks                                           Dr. James F. Brien
                                              BIOGRAPHIES

Dr. Michael A. Adams

A Professor in the Department of Pharmacology and Toxicology, Dr. Michael Adams was first appointed at
Queen’s as an Assistant Professor in 1988. Dr. Adams received his Ph.D. at the University of Western
Ontario followed by a MRC (now CIHR) post-doctoral fellowship in Melbourne, Australia. He has previously
received the Mihran and Mary Basmajian Award for Excellence in Medical Research at Queen's University,
the Young Investigator Award of the Canadian Hypertension Society and the Education Award of the
Faculty of Health Sciences, Queen’s University. He previously held a Heart & Stroke Foundation Senior
Research Scholarship and held a Career Award in Medicine from the Medical Research Council-Health
Research Foundation/PMAC.

Ms. Margaret Alden

Since its inception in 2000, Ms. Alden has been the Managing Director of the Human Mobility Research
Centre (HMRC). HMRC has gained national and international attention for the development of innovative
new mobility technologies and has become one of Canada's leading musculoskeletal research centres. Ms.
Alden has extensive experience in leading multi-disciplinary, inter-institutional research teams that interact
successfully with industry.

Ms. Shannon A. Bainbridge

Shannon is in the final year of her PhD in the department of Anatomy and Cell Biology. Her graduate
research training has explored placental function both during healthy pregnancies as well as during
pregnancies complicated with placental diseases such as pre-eclampsia. She is currently funded by a
studentship through the Strategic Training Initiative in Research in Reproductive Health Sciences
(STIRRHS), a program sponsored by CIHR in collaboration with the Association of Professors of Obstetrics
and Gynaecology of Canada (APOG).

Dr. Mark A. Bisby

Mark Bisby graduated from Oxford University in 1972. Following a postdoctoral fellowship at McMaster
University, his first faculty appointment was with the Departmnet of Medical Physiology at the University of
Calgary. In 1989 he became Head of the Department of Physiology at Queen’s University and in 1997 left to
become the Director of Programs Branch of the Medical Research Council (MRC) of Canada. In his capacity
as Director at MRC, and subsequently CIHR, Dr. Bisby played an important role in the smooth transition
between MRC and CIHR, and in implementing the broadened mandate of CIHR. As Vice-President of the
Research Portfolio at CIHR, Dr. Bisby works with CIHR’s Institutes, the research community, and other
stakeholders to set the research agenda for CIHR, and to maintain and improve the environment for
excellence in health research in Canada.

Dr. James F. Brien

Jim Brien, PhD, is a Professor in the Department of Pharmacology and Toxicology and Director of Research
in the Faculty of Health Sciences at Queen’s University. He currently is the Canadian Institutes of Health
Research–University Delegate at Queen’s. His longstanding research program on fetal alcohol spectrum
disorders is focused on the elucidation of mechanisms of the brain injury and the discovery of innovative
treatment strategies.
Dr. Timothy Bryant

Dr. Timothy Bryant is a Professor in Mechanical Engineering at Queen's University with cross appointments
to the Departments of Surgery and the School of Physical and Health Education. He is also the Chair of the
Scientific Committee for the Human Mobility Research Centre. Throughout his career, Dr. Bryant has played
a leadership role in advancing musculoskeletal research through interdisciplinary teams. Most recently he is
receiving international attention for his work in the design of a low cost prosthetic foot for land mine victims
and for the design of a new backpack for the Canadian Military.

Dr. Wendy Craig

Dr. Craig is an Associate Professor in the Department of Psychology at Queen’s University. She received her
Ph.D. in 1993 from York University. Her research program focuses on three areas. The first examines healthy
relationships among children, adolescents, and adults. The second addresses the risk and protective factors
associated with bullying and victimization in family, peer, individual, school and social relationships. The
third research program addresses the development of aggression in females as demonstrated in romantic
relationships, dating violence and young girls with behavior problems. In recognition of her work on
bullying and victimization, she is the recipient of an Investigator Award from the Canadian Institutes of
Health Research. She is currently co-leading a Canadian National Initiative designed to Prevent Bullying
Problems in Canada. Dr. Craig is published widely, including on topics of bullying and victimization, peer
processes, sexual harassment and aggression in girls.

Ms. Courtney R. Green

Courtney Green is a Ph.D. student with the supervision of Dr. James Reynolds. Her research interests are
focused on developing a novel diagnostic tool for fetal alcohol syndrome (FAS) using saccadic eye movement
tasks. This tool would help identify the specific types of brain injury associated with FAS, and provide an
objective measure for evaluating various therapeutic interventions.

Dr. Samuel K. Ludwin

Samuel Ludwin is Professor of Neuropathology in the Department of Pathology and Molecular Medicine,
Associate Dean of Research Faculty of Health Sciences Queen's University, and Vice-President (Research
Development) of the Kingston Hospitals. His research program focuses on clinical studies of multiple
sclerosis and on cellular and molecular mechanisms of demyelination and myelination.

Dr. Thomas E. Massey

Thomas Massey is Professor and Head of the Department of Pharmacology & Toxicology, as well as being
Co-chair of the Environment & Human Health Research Group at Queen's. He trained at the University of
Western Ontario, Queen's University, and the National Institute of Environmental Health Sciences (USA).
Dr. Massey's CIHR-funded research focuses on determining how drugs and environmental contaminants
initiate lung cancer and lung fibrosis.

Dr. Jennifer Medves

Jennifer Medves, RN, PhD, is an Assistant Professor in the School of Nursing and an Ontario Ministry of
Health Career Scientist. Her research interests are in rural health, particularly sustaining rural maternity
practice and preparing health professionals to work in rural and remote Canada. She has funding from CIHR
and Health Canada to support these research programmes.
Dr. James N. Reynolds

Dr. James Reynolds is a Professor in the Department of Pharmacology & Toxicology. Dr. Reynolds’ research
interests are focused on understanding the mechanisms of the brain injury, and the resulting behavioural and
cognitive deficits, that are induced by prenatal exposure to alcohol. The long-term goal is to understand how
prenatal exposure to alcohol alters brain neurochemistry, and thus brain function, in offspring.

Dr. R. Kerry Rowe

Dr. Kerry Rowe is Vice-Principal (Research) at Queen’s University. Author of more than 360 publications,
he has extensive research and consulting experience in the geotechnical and geoenvironmental engineering
field. His research has been recognized by numerous awards including most recently the Killam Prize in
Engineering. He is a former NSERC Steacie Fellow and is a fellow of both the Royal Society of Canada and
the Canadian Academy of Engineering. Dr. Rowe is past president of the Canadian Geotechnical Society, a
past president of the International Geosynthetics Society, President-elect of the Engineering Institute of
Canada and editor of the journal Geotextiles and Geomembranes.

Ms. Joanne Wan

Joanne Wan received her B.Sc. (Hons) from the University of Toronto in 2001. Since then, she has been a
Ph.D. student in the Department of Pharmacology and Toxicology at Queen’s University, working with the
supervision of Dr. Louise Winn. She is investigating the effects of the environmental chemical benzene on
the c-Myb signaling pathway as a potential mechanism of leukemogenesis.

Dr. Louise M. Winn

Louise Winn received her Ph.D. from the University of Toronto in 1999 with the supervision of Dr. Peter
Wells, investigating the role of oxidative stress in developmental toxicology. She completed her postdoctoral
training in the laboratory of Dr. Scott Ness at the University of New Mexico in Albuquerque, New Mexico,
investigating the role of the c-Myb signal transduction pathway involved in leukemias. Since arriving at
Queen’s in January 2001 as an Assistant Professor jointly in the Department of Pharmacology and
Toxicology and the School of Environmental Studies, her research efforts have focused on determining how
both environmental chemicals and therapeutic agents cause toxicity to the developing embryo. Her research
funding includes CIHR, the JP Bickell Foundation, CFI New Opportunities, PREA and an Rx&D
HRF/CIHR Research Career Award.

The organizing committee gratefully acknowledges the following institutions for their sponsorship
of this Public Forum:

				
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