Curriculum vitae for Patrik Brundin Fetal Movement

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Curriculum vitae for Patrik Brundin Fetal Movement Powered By Docstoc
					Curriculum vitae for Patrik Brundin

  Personal data        Name Patrik Brundin
                       Date of birth December 26, 1961

  Position title       Professor of Neuroscience

  Institution and Location                      Degree    Year(s)   Field of Study
  Lund University, Sweden                       M.D.      1992      Medicine
  Lund University, Sweden                       Ph.D.     1988      Medical Science
  Lund University, Sweden                       B.Sc.     1983      Medicine
  United World College of the Atlantic, Wales   I.B.      1980      Natural sciences

  Professional Positions
  2000      Appointed professor in Neuroscience at Lund University, Sweden.
  2000-2000 Professor of Experimental Neuropathology at Copenhagen University, DK
  1999      Permanent position as Associate professor of Neuroscience at Lund
  1998      Lecturer in Experimental Medicine at Lund University.
  1995-1998 Swedish Medical Research Council research position.
  1994      License to practice medicine (läkarlegimitation).
  1994      Neurology, clinical training (3 mo.).
  1992-1994 80% clinical internship, 20% research associate.
  1990-1992 Clinical program Lund Medical School.
  1988-1990 Post-doctoral position at the Dept of Medical Cell Research, Lund University.
  1983-1988 Graduate student (supervisor Anders Björklund).
  1981-1988 Various junior teaching positions.

  Honors, Awards, Other Professional Activities
  2002-today Coordinator of the EC-sponsored Marie Curie Training Site on
             “Neurodegeneration, cell rescue and brain repair”.
  2001-today Coordinator of the EC-sponsored Concerted Action on “Early Pathogenetic
             Markers for Slow Neurodegenerative Diseases”.
  1996-2001 Dissertation of 7 PhD students and 1 Master student.
  1987-today Participation in clinical trials with intracerebral grafts in 19 Parkinsonian
  2001       Awarded the Catedra Santiago Grisolía Chair Prize, Valencia, Spain.
  2001       Presented with The Outstanding Young Persons of the World Award for
             research and academic leadership by the Swedish Junior Chamber.
  2000       Coorganiser of the international conference entitled "The role of mitochondria
             in apoptosis and neurodegeneration", June 2000.
  1999       Chairman of the Gordon conference entitled "CAG triplet repeat disorders"
             July 15-20, 2001 Mount Holyoke College, MA, USA.
  1999       Awarded Dr Eric K. Fernström Foundation's Prize to Young Swedish
  1999       Harvard Macy Program for Leaders in Medical Education, Boston, USA.
  1999       Chairman of Research Strategy 2000 Group, Medical Faculty, Lund.
  1999       Organizer of the international conferences entitled "CAG triplet repeat
             expansion. in neurologic disease" and "The future of neural grafting in
             Parkinson's disease" at Wallenberg Neuroscience Center, Lund University,
1999-today    Editorial board of Experimental Neurology.
1998-today    Editorial board of Neuroscience.
1998-today    Section editor for neuroscience in Cell Transplantation.
1997-2000     Chairman of the "Experimental Work" Group in the EU-sponsored
              Concertation of the European strategies for intervention in Parkinson's
              disease with special emphasis on functional neurosurgery (NIPD).
1997          Project evaluation committee for the National Network in Neuroscience,
1997-1999     Chairman of the Neurobiology Club in Lund.
1995          Founder of the Section for Neuronal Survival, Lund University.
1994-today    Member of the editorial board of Cell Transplantation.
1994          Awarded the Swedish Medical Research Council grant for young promising
1994-today    President of NECTAR (Network for European CNS Transplantation and
1994          New Investigator lecture award, Montreal Neurology Institute.
1990          Member of the local organizing committee for the international
              Fernström symposium on Intracerebral transplantation in movement
              disorders: experimental basis and clinical experiences".
1990-today    Member of over 25 thesis review committees.
1989          Presented with the Oscar II award for best medical thesis in Lund 1988-1987.

Selected peer-reviewed publications (in chronological order)
(Publications selected from 135 original papers and 60 review articles/book

1.     Isacson O, Brundin P, Kelly PAT, Gage FH and Björklund A (1984) Functional
       neuronal replacement by grafted striatal neurons in ibotenic acid lesioned rat
       striatum. Nature 311: 458-460.
2.     Brundin P, Nilsson OG, Strecker RE, Lindvall O, Åstedt B and Björklund A
       (1986) Behavioural effects of human fetal dopamine neurons grafted in a rat
       model of Parkinson's disease. Exp Brain Res 65: 235-240.
3.     Brundin P, Strecker RE, Widner H, Clarke DJ, Nilsson OG, Åstedt B, Lindvall O
       and Björklund A (1988) Human fetal dopamine neurons grafted in a rat model of
       Parkinson's disease: immunological aspects, spontaneous and drug-induced
       behaviour, and dopamine release. Exp Brain Res 70: 192-208.
4.     Lindvall O, Brundin P, Widner H, Rehncrona S, Gustavii B, Frackowiak R,
       Leenders KL, Sawle G, Rothwell JC, Marsden CD and Björklund A (1990)
       Grafts of fetal dopamine neurons survive and improve motor function in
       Parkinson's disease. Science 247: 574-577.
       Wictorin K, Brundin P, Gustavii B, Lindvall O and Björklund A (1990)
       Reformation of long axonal pathways in adult rat central nervous system by
       human forebrain neuroblasts. Nature 347: 556-558.
6.     Grabowski M, Brundin P and Johansson BB (1993) Functional integration of
       cortical grafts in infarcted rat neocortex. Annal Neurol 34: 362-368.
7.     Nakao N, Frodl EM, Widner H, Carlson E, Eggerding FA, Epstein CJ and
       Brundin P (1995) Overexpressing Cu/Zn-superoxide dismutase enhances
       survival of transplanted neurons in a rat model of Parkinson's disease. Nature
       Med 1: 226-231.
8.    Grasbon-Frodl EM, Nakao N, Lindvall O and Brundin P (1996).Phenotypic
      development of the human embryonic striatal primordium: a study of cultured
      and grafted neurons from the lateral and medial ganglionic eminences.
      Neuroscience 73: 171-183.
9.    Grasbon-Frodl EM, Andersson A and Brundin P (1996) Lazaroid treatment
      prevents death of cultured rat embryonic mesencephalic neurons following
      glutathione depletion. J Neurochem 67: 1653-1660.
10.   Nakao N and Brundin P (1997) Effects of a-phenyl-tert-butyl nitrone on neuronal
      survival and motor function following intrastriatal injections of quinolinate or 3-
      nitropropionic acid. Neuroscience 76: 749-761.
11.   Barkats M, Nakao N, Grasbon-Frodl EM, Biland-Bleuel A, Revah F, Mallet J and
      Brundin P (1997) Intrastriatal grafts of embryonic mesencephalic rat neurons
      genetically modified using an adenovirus encoding human Cu/Zn superoxide
      dismutase. Neuroscience 78: 703-713.
12.   Duan W-M, Widner H, Cameron RM and Brundin P (1998) Quinolinic acid-
      induced inflammation in the striatum does not impair the survival of neural
      allografts in the rat. Eur J Neurosc 10: 2595-2606.
13.   Schierle GS, Hansson O, Leist M, Nicotera P, Widner H and Brundin P (1999)
      Caspase inhibition reduces apoptosis and increases survival of nigral
      transplants. Nature Med 5: 97-100.
14.   Hansson O, Petersén Å, Leist M, Nicotera P, Castilho RF and Brundin P (1999)
      Transgenic mice expressing a Huntington's disease mutation are resistant to
      quinolinic acid-induced striatal excitotoxicity. Proc Natl Acad Sci USA 96: 8727-
15.   Schierle GS, Leist M, Martinou J-C, Widner H, Nicotera P and Brundin P (1999)
      Differential effects of Bcl-2 overexpression on fiber outgrowth and survival of
      embryonic dopaminergic neurons in intracerebral transplants. Eur J Neurosci
      11: 3073-308.
16.   Piccini P, Brooks DJ, Bjorklund A, Gunn RN, Grasby PM, Rimoldi O, Brundin P,
      Hagell P, Rehncrona S, Widner H, Lindvall, O (1999) Dopamine release from
      nigral transplants visualized in vivo in a Parkinson's patient. Nature Neurosci
17.   Brundin P, Pogarell O, Hagell P, Piccini P, Widner H, Schrag A, Kupsch A,
      Crabb L, Odin P, Gustavii B, Björklund           A, Brooks DJ, David Marsden C,
      Oertel WH, Quinn NP, Rehncrona S and Lindvall O (2000) Bilateral caudate
      and putamen grafts of embryonic mesencephalic tissue treated with lazaroids
      in Parkinson's disease. Brain 123: 1380-1390.
18.    Lotharius J, Barg S, Wiekop P, Lundberg C, Raymond HK, Brundin P (2002).
      Effect of mutant alpha-synuclein on       dopamine homeostasis in a new human
      mesencephalic cell line. Journal of Biological Chemistry, in press.
19.    Hagell P, Piccini P, Björklund A, Brundin P, Rehncrona S, Widner H, Crabb L,
      Pavese N, Oertel WH, Quinn N, Brooks DJ, and Lindvall O (2002). Dyskinesias
      following neural transplantation in Parkinson's disease. Nature Neuroscience

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