The grant-writing course is an intensive experience designed

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                   Clinical Research Training Program

                          GRANT WRITING COURSE
                             Class of 2009
                            Summer/Fall 2008

     The grant-writing course is an intensive experience designed
to impart the skills necessary to produce a proposal for NIH career
development grant (K23) or an R01/R21. The course consists of
lectures which are dispersed during the summer and include an
overview of the NIH system, scientific writing for grants and papers
and constructing specific aims. The second part of the course
involves meeting in small assigned groups with a leader during which
time you will produce sections of your grants until a finished
proposal is produced. The critical function of the small group is to
obtain detailed feedback from your leader and group members on your
evolving grant. In addition, Dr. Schoenbaum is available to meet and
discuss your grant, by appointment.

     These groups will start meeting in early July to begin the
process of developing each of your specific aims and quickly move on
to the other sections. The groups will meet every other week so you
have time to write the grant sections. The Specific Aims are the
most important part of the grant as all sections are linked to them.
The grant sections should be emailed to leader and your group with
enough lead time for them to read it and make written comments. Each
group will work out its meeting time and place. There are no
meetings in November so you have free time to finalize the grant,
which is due Friday, Nov 28th.

     The course then culminates in three mock NIH study sections in
December. All Scholars will be present at the sessions to observe
and not speak. After the session is over there will be short
debriefing period and Scholars can ask questions and talk with the
reviewers. Scholars will receive the written reviews of their
grants. I recommend you view a video made by NIH of a mock study
section in advance of our mock study sections.
(http://www.csr.nih.gov/video/video.asp)

     The recommended text is “The Grant Application Writer’s
Workbook.” It deals with R01s but has a good specific aims section
and someday you will write and get an R01. Purchase it on the web at
http://www.grantcentral.com/workbook_nih_sf424.html.

      I also recommend checking out the website of Einstein and
Monte’s Institute For Clinical and Translational Research, grant
writing tools, http://ictr.aecom.yu.edu/GrantProTools.aspx.


     IT IS CRITICAL THAT YOU START WORKING ON YOUR GRANTS DURING
THE SUMMER. There are home housekeeping chores that you can do now
that will make the final grant preparation easier. First, have an up
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to date NIH biosketch, and print out a face page for the grant (URL
below). Although grants are now submitted electronically, for this
course the grant is printed out for the reviewers and we need an
face page. Also read the NIH instructions for the grant you are
writing and familiarize with the requirements for grant, including
the specified length of the abstract, the title length and font size
requirements and overall page limitations. You should go to website
of the NIH institute that focuses on your research area to obtain
information about their career development program. We will provide
you with a booklet with copies of successful K23 grants from CRTP
graduates. The following sections are required for this course:
     1.Face page with Title
     2.Scholar’s NIH Biosketch
     3.Abstract
     4. Career Development Plan (see p. 59 of PHS 398 App booklet)
           a. The Candidate’s Background
           b. Career Goals and Objectives: Scientific Biography
           c. Career Development/Training Activities During Award
                Period
           d. Training in the Responsible Conduct of Research
           (N.B. Mentor or Reference letters - NOT REQUIRED)

     5.Research Plan
     6.Human Subjects
     7.Literature Cited

     Note that you are not required to submit the resources and
environment, budget, biosketchs of your key personnel, mentor
letters or a data sharing plan.

The following URLs will get you to the instructions for a K23 and
forms.

PA-05-143,this site is ONE example of an active announcement for the
K23. Focus on Section IV.6 entitled Other Submission Requirements,
for info on the grant sections candidate, career development plan,
training in responsible conduct of research and research plan.
http://grants1.nih.gov/grants/guide/pa-files/PA-05-143.html


There are highly relevant instructions in the PHS 398 Application
booklet. GO to the section on Research Career Awards in this site.
Go to page I-59.
http://grants.nih.gov/grants/funding/phs398/phs398.doc#_Toc186425179


Obtain the Face Page at:
http://grants.nih.gov/grants/funding/phs398/fp1.doc

Obtain Abstract Form here, now called Project Summary and Relevance.
Disregard key personnel.
http://grants.nih.gov/grants/funding/phs398/fp2.doc
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                           MILESTONES
DATE                 “DELIVERABLE”
Tues July    1       Preparing an NIH Grant Proposal- How the NIH
                     Works Lecture (Dr. Hathaway)
                     Course overview    – Drs. Schoenbaum)
Week of July 1       Small group meeting with leader (discuss aims,
                     plan future meetings and process) *
Thurs July 3         Specific Aims (Dr. Hathaway)
Week of July 14      Small group meet: specific aims and Biosketch
                     due
Week of July 28      Small group meet: candidate I due
Tues July 29         Writing for grants and papers (Dr. Arnsten)
Thurs July 31        Library Skills:    managing references
Week of Sept 8       Small group meet: candidates II due
Week of Sept 22      Small group meet: research plan- background &
                     significance due
Week of Oct 6         Small group meet: research plan –methods, human
                     subjects due
Week of Oct 20       Small group meet: research plan – preliminary
                     data and timeline due,   face page completed
Week of Nov 3        Small group meet: wrap up
November 28          Final Product Due (E-mail in one PDF file to Ann
                     Marie by 5pm)
December TBN         Mock Study Section 1
December TBD         Mock Study Section 2
December TBD         Mock Study Section 3
       *Small groups can make individual meeting plans using this as a
       guide for getting things done by Nov 28.