SOLUTIONS Brochure homegrown vaccine by benbenzhou


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									       ooking for reliable, quality                                                                                      The UNIVERSITY OF REGINA

L      ingredients, analytical or
       processing capabilities,
innovative research, or a path to
                                                                                         University of

                                                                                   • 144,000 ft2 of fully equipped
                                                                                                                         provides research strengths in
                                                                                                                         information technology, energy and
                                                                                                                         the environment. The Faculty of
                                                                                                                         Science is committed to sustaining
                                                                                                                                                                                                                    AAFC Saskatoon
                                                                                                                                                                                                                     Research Centre

commercialization? Saskatchewan                                                      laboratories with bioreactor                                                                                               • More than 350 staff including
                                                                                                                         excellence in the creation and                                                           80 professionals on
offers the solution!                                                                 systems, fermentation
                                                                                                                         dissemination of knowledge by                                                            approximately 1,000 ha of
                                                                                     technologies, fluorescence,
                                                                                     spectroscopy and microscopy,
                                                                                                                         research, scholarly publication and                                                      research farmland
Beneath an expansive prairie sky,                                                    protein and small molecule          teaching in both basic and applied                                                     • Infrastructure and capability to
                                                                                     x-ray crystallography and DNA       sciences.                                                                                isolate, characterize and
Saskatchewan’s R & D community                                                                                                                                    Dedicated to improving the
                                                                                     analysis and synthesis                                                                                                       manipulate genes, oils,
enjoys a unique synergy. From the                                                                                                                                 competitiveness of the Canadian                 proteins, secondary
                                                                                   • Over 3,200 ha of experimental       Recognized globally for research
research and analytical stages of                                                    farmland and computer-                                                       agri-food sector, AGRICULTURE                   metabolites, and enzymes to
                                                                                                                         and innovation, the NATIONAL
                                                                                                                                                                  AND AGRI-FOOD CANADA’S                          develop value-added
detecting potential for novelty to                                                   controlled plant-growth             RESEARCH COUNCIL – PLANT
                                                                                     chambers                                                                     SASKATOON RESEARCH CENTRE                       opportunities with plants
the late stages of transforming that                                                                                     BIOTECHNOLOGY INSTITUTE (PBI)                                                          • Progressive insect and plant
                                                                                   • Saskatchewan Structural             has expertise in areas of seed oils,     (AAFC-SRC) facilitates the
potential into a product, our world-                                                 Sciences Centre, a world-class                                                                                               pathogen containment facilities
                                                                                                                         natural health products, anti-           development and transfer of
class expertise covers the entire                                                    facility offering expertise in                                                                                               and microbial fermentation lab
                                         This intersection of human, animal                                              nutritional compounds, disease           innovative technologies.                        for research and development
spectrum of product and process                                                      synchrotron science, materials
                                         and plant science opens roads to            science, structural biology,        resistance,                                                                              of biological control agents
creation.                                research previously unimagined:                                                 environmental stress                                                                   • Conservation, documentation
                                                                                     biophysical chemistry, magnetic                                 National Research
                                         • College of Agriculture, in                resonance spectroscopy, and         tolerance, plant                                           AAFC – SRC’s                  and distribution of diverse
                                                                                                                                                        Council – Plant
From imagination to inspiration to          conjunction with the Western             laser technology                    genomics, proteomics,          Biotechnology
                                                                                                                                                                                    research activities           germplasm (100,000
                                            College of Veterinary Medicine         • Many associated research                                                                       work to improve               accessions) including the
discovery and innovation, it is                                                                                          transformation                     Institute
                                                                                     centers, for example VIDO,                                                                     germplasm of oilseed          world-base collections of barley
pioneering research and development         (WCVM) is focusing on livestock                                              methodologies and cell
                                                                                     CLSI and Prairie Feed Resource                                 • State-of-the-art research     and forage crops, to          and oat within Plant Gene
that moves today’s ideas into               genomics with an emphasis on                                                 culture techniques.
                                                                                     Centre                                                          and analytical capabilities                                  Resources of Canada
tomorrow’s technologies.                    production traits, nutritional                                                                                                          identify effective pest
                                                                                                                                                     such as non-destructive        control practices, to
                                            biochemistry and toxicology, and                       As part of the NRC,         imaging through NMR,
                                            feed processing                                                              NRC-PBI performs,                                          develop processes
As one of Canada’s major academic                                                                                                                    mass spectrometry, and
                                         • Colleges of Medicine, Pharmacy                                                assists and promotes                                       and products that
and research institutions, the                                                                                                                       DNA synthesis and                                        The VACCINE AND INFECTIOUS
                                            and Nutrition, and Agriculture are                                           strategic discovery         sequencing                     expand the
UNIVERSITY OF SASKATCHEWAN                                                                                                                                                                                    DISEASE ORGANIZATION (VIDO) is
                                            investigating applied and                                                    research and              • Industry Partnership           utilization of crops,
(U of S) is a driving force for                                                                                                                                                                               a centre of excellence for both
                                            analytical food chemistry to                                                 innovation in plant         Facility, a 74,000 ft2         and through Plant
innovation, having laid claim to a                                                                                                                                                                            human and animal vaccine research
                                            develop novel functional foods                                               biotechnology in            expansion built to             Gene Resources of
number of firsts for science and                                                                                                                                                                              and development. Credited with five
                                            and natural health products to                                               partnership with key        incubate start-up plant        Canada, to conserve,
technology:                                                                                                                                          science companies, offers                                ‘world firsts’ VIDO has a 30 year
                                            promote healthy lifestyles                                                   stakeholders, to                                           document and
                                                                                                                                                     research expertise and a                                 history in commercialization of
                                         • Vaccine and Infectious Disease                                                improve and diversify                                      distribute diverse
• the first genetically engineered                                                                                                                   wide range of powerful                                   vaccines and novel formulation and
                                            Organization (VIDO) in                                                       Canadian industry and                                      germplasm.
  vaccine for animals                                                                                                                                research tools through fee-                              delivery systems.
                                            collaboration with the WCVM                                                  strengthen Canada's         for service or collaborative
• the first conversion of an antibody
                                            and Colleges of Medicine,                                                    competitive position in     arrangements
  into an enzyme, potentially                                                                                                                                                      Leading-edge
                                            Pharmacy and Nutrition are           The U of S provides a continuous        the global knowledge-
  leading to better drugs and drug                                                                                                                                                 research in
                                            developing vaccines for animal       flow of bright young science,           based economy.   
  therapies                                                                                                                                                                        carbohydrate and
                                            and human health along with          business, and social science
• the introduction of more than 100                                                                                                                                                protein charac-
                                            novel drug delivery systems          graduates to support the future         Its research encompasses three
  new crop varieties                                                                                                                                            terization, isolation and identification
                                         • College of Engineering, along side    growth of the science industry. For     broad themes:
                                            the College of Agriculture, is       example, the College of Commerce                                               of secondary plant compounds, as
                                                                                                                         1) Diversifying plants to produce
Life science research thrives at the U      developing fermentation              offers an innovative one-year MBA                                              well as novel processes for the
                                                                                                                             new oils, health products, and
of S through the College of Medicine,       technologies that focus on           program specializing in                                                        refinement of compounds such as oat
                                                                                                                             other industrial compounds                                                       VIDO’s Functional Pathogenomics of
College of Pharmacy and Nutrition,          biological conversion of             biotechnology, agribusiness or health                                          components and flax lignans, has led
                                                                                                                         2) Improving crop productivity                                                       Mucosal Immunity program, funded
Western College of Veterinary               agricultural wastes into high-       services management. Its intensive,                                            to innovative products for the
                                                                                                                         3) Developing the enabling tools and                                                 by the largest Genome Canada grant
Medicine, Virtual College of                valued animal feed supplements,      highly integrated format is designed                                           cosmetics, personal health care and
                                                                                                                             technologies needed for crop                                                     in animal and human health, aims to
Biotechnology, College of                   and bioreactor systems to            to develop management ability for                                              food sectors, and for industrial
                                                                                                                             improvement and plant                                                            increase the understanding of how
Engineering and the College of              economically produce ethanol         science and technology related                                                 applications.
                                                                                                                             diversification                                                                  infectious diseases and immunity
Agriculture.                                from grain starches                  professions.
microbial pathogens operate. These        CANADIAN LIGHT SOURCE INC.               Experts in analytical science, the                                                  The POS PILOT PLANT                       production facility can find a solution
findings will be used to develop new      (CLSI), is serving academic,             SASKATCHEWAN RESEARCH                                                               CORPORATION, a contract applied           to all their processing needs here.
and effective strategies for improving    government and industrial researchers    COUNCIL (SRC) applies the leading-                                                  R&D and small-scale toll processing
human health and animal                   in pharmaceuticals, environmental,       edge knowledge developed in                     Research Council                    facility, specializes in process and
productivity.                             material and life sciences.              Saskatchewan and uses it to solve                                                   product development involving
                                                                                   unique situations.                                                                  extraction, fractionation, purification          Innovation Place
                                                                                                                               • Fermentation Pilot Plant                                                                Bio Processing
INTERVAC, a new multi-million,                                                     SRC's Laboratories Services Division                                                and modification of bio-based
                                                                                                                                 provides production and                                                                     Centre
Level 3 biosafety vaccine research                                                 in Saskatoon and Regina assists                                                     materials. During its 27 years of
                                                                                                                                 process development services
laboratory scheduled for completion                                                clients with environmental                                                          operation, POS has served clients           • 9,310 ft2 of wet processing plant
                                                                                                                                 for vaccines and therapeutics,
in 2009, will perform vaccine                                                      monitoring and development of                                                       from 37 different countries. Their            and 240 ft2 of laboratories
                                                                                                                                 and supports bacterial, fungal,
research and development in                                                        Saskatchewan's resources, including                                                 grams-to-tonnes process and product           equipped with a wide range of
                                                                                                                                 algal, and mammalian cultures
response to emerging and persistent                                                specialized geochemical analyses for                                                development services offer clients the        wet processing equipment to
                                                                                                                                 from bench to 300 L scales,                                                         carry out extraction or
pathogens such as West Nile virus,                                                 the mineral industry. The Ag &                                                      flexibility to choose the scale that
tuberculosis and avian influenza.                                                                                                under GLP and BioSafety Level         best suits their needs - lab,                 fractionation work using
                                                                                   Biotechnology Division includes               2 conditions                                                                        aqueous and/or alcohol solvents
                                                                                   Bova-Can and GenServe Laboratories                                                  intermediate or pilot plant scale.
                                                                                                                               • GenServe Laboratories services                                                    • Clients can bring their own or
                                                                                   providing DNA-based genomic                   include high throughput DNA                                                         rental equipment to test different
                                                                                   services for livestock and plants, and                                              Once POS clients have developed
         Vaccine and                                                                                                             sequencing, testing of plant                                                        processes and concepts or to
     Infectious Disease                                                            a Fermentation Technologies Unit.                                                   their process or product and require          train staff prior to start-up of a
                                          Sometimes referred to as the ‘Swiss                                                    varieties, genetic marker             large-scale processing, companies
        Organization                                                               Other SRC labs include the Petroleum                                                                                              client’s own facility
                                          Army knife’ of research for its                                                        development and DNA finger-           can use the Innovation Place Bio
                                                                                   Analysis Lab, the Outdoor Testing                                                                                        
  • 100,000 ft2 research facility         versatility, the CLSI synchrotron can                                                  printing of crops, trees, insects,    Processing Centre, also located in the
                                                                                   Facility and the Natural Gas Vehicles
    including a 65ha research             be used to examine a vast array of                                                     wildlife populations and              Saskatchewan life science cluster.
    station                               projects from engineering biofilms for                                                 microorganisms to establish
  • State-of-the-art virology,            use in environmental remediation, to                                                   identity and assist breeders
    bacteriology, biochemistry and        detecting the level of mercury in fish           Canadian Light                      • Bova-Can Laboratories provide                POS Pilot Plant
    immunology laboratories               sold for human consumption, or                      Source                             genetic services for livestock
  • Over 120 staff including more         monitoring the movement of toxins          • Collaborative and full fee-for-           pure-bred parentage                     • The largest pilot plant operation
    than 45 scientists and                from soils to plants to insects.             service analysis for academia and         certifications and genetic                 of its kind in North America
    veterinarians with advanced                                                        industry                                  disease and quantitative trait             with a team of more than 80
    degrees                               Synchrotron light is a valuable tool       • Seven beam lines and                      screening using blood typing               specialists and support staff
                                          for investigating chemical structures        experimental end stations                 and DNA testing, as well as             • 5 separate cGMP-compliant
  • Greater than 65 US patents
                                          regardless of the state of the sample          • High Resolution Far-Infrared                                                     processing areas and 11 fully-
    awarded to date with over 30                                                                                                 DNA microsatellite markers for
                                          (solid, liquid or gas) and can even              Spectroscopy                                                                     equipped laboratories in a
    more pending                                                                         • Mid-Infrared                          parentage testing of llamas,               54,000 ft2 facility
  • Participation in more than 60         examine living tissue with no                                                          alpacas, elk, sheep, goats and
                                                                                           Spectromicroscopy                                                             • Over 300 Canadian companies
    agreements, including                 damage. Plants, for example, can be            • Plane Grating                         swine                                      served in the past 10 years with
    confidentiality, material transfer,   put in a synchrotron beam, analyzed,             Monochromator (PGM)                                                              hundreds of product
    and collaborative research
                                          and then put back in the greenhouse.           • Spherical Grating                                         introductions
    agreements, as well as service                                                         Monochromator (SGM)
                                                                                         • Soft X-ray Spectromicroscopy                                                   
                                                                   • Macromolecular
                                                                                           Crystallography                                                             The INNOVATION PLACE BIO
                                                                                                                             Analyzing biological life to unlock its
                                                                                         • Hard X-ray Microanalysis                                                    PROCESSING CENTRE provides toll
                                                                                     • Phase II beamlines will include:      secrets may be the first stage in
Once there is an understanding of                                                                                                                                      or custom processing on a large-
                                                                                          • Biomedical Imaging and           taking an idea to commercialization,
the possibilities that exist in                                                                                                                                        contract basis for the agri-food,
                                                                                            Therapy (BMIT)                   but just as important is the
microbes, plants and animals,                                                                                                                                          nutraceutical and cosmetic industries.
                                                                                          • Soft X-ray                       processing stage. Companies and
scientists can develop innovative                                                         • Resonant Elastic and Inelastic                                             The centre covers the entire spectrum
ways of using this potential to meet                                                                                         agencies in Saskatchewan possess          of processing from extraction and         INNOVATION PLACE, one of the
                                                                                            Soft X-Ray Scattering
not only agricultural and industrial                                                      • High Throughput                  expertise in all these areas, while       fractionation to the downstream           most successful, rapidly growing
but also health challenges.                                                                 Macromolecular                   meeting extremely stringent safety        refinement of a product. Companies        technology parks in North America,
                                                                                            Crystallography                  standards.                                looking for ways to introduce a           develops, manages, and operates
After five years of construction, the                                                     • Nanostructures Facility                                                    product to the marketplace without        commercial facilities to support the
only Canadian synchrotron,                                                                                                                                             investing heavily in their own            R&D community in Saskatoon.
This 32-hectare science park is home                                            Innovative small to medium              AGRISOMA BIOSCIENCES INC. is                                                    flavour. These features, plus their
to numerable new and value-added                                                enterprises (SMEs) also thrive in       one more example of the over 30                                                 commitment to superior quality and
products, processes and                                                         Saskatchewan’s fertile atmosphere,      SMEs involved in Saskatchewan’s             Saskatchewan Food                   customer service, allow this company
technologies. The approximately                                                 from the development and                science and technology sector. A           Industry Development                 to offer solutions for quality food
2,100 staff, employed by 130                                                    manufacture of plant inoculants at      private development stage                         Centre                        ingredients.
organizations residing within                                                   Philom Bios, the advanced crop          biotechnology company, Agrisoma is
                                                                                                                                                                   • Hazard Analysis and Critical
Innovation Place, contribute over                                               research at Performance Plants or       dedicated to developing and                  Control Point, and Quality
$260 M per year to the economy of                                               Saskatchewan Wheat Pool, to animal      commercializing its chromosome-              Assurance applications
Saskatchewan.                                                                   research at MetaMorphix. Natural        based gene delivery and expression         • Flexible production phase can
                                                                                health product (NHP) and functional     technology to enable the                     include use of Food Centre
                                                                                food companies (Bioriginal Food and     development of high value traits in          equipment, your own
                                                                                Science Corp. or InfraReady             crops, like grains with enhanced             equipment, or any combination
                                                                                Products), bioproduct companies         nutrition, and enable the production       • Wide variety of food processing
                                                                                (Milligan Biotech or MCN                of industrial and therapeutic proteins       equipment available, including
                                                                                Bioproducts), service providers         in plant-based systems.                      grinders, slicers, fryers,
                                       The REGINA RESEARCH PARK, one                                                                                                 smokers, packagers and scales
                                                                                (Phenomenone Discoveries) and field
                                       of Canada's newest R&D parks, is                                                                                            • Packaging equipment available
                                                                                trial and variety evaluation            An aging population combined with            for both wet and dry
                                       located adjacent to the University of    companies (Ag-Quest or ICMS Inc.)       a rising awareness of public health is       ingredients. The creation of the
                                       Regina and builds on the strengths of    show the broad range of capabilities    increasing our interest in NHPs and          labels is hampered only by your
                                       the University to develop knowledge      available to take an idea all the way   functional foods and, therefore,             imagination
                                       clusters in fields such as information   to a commercial product.                increasing value-added opportunities.
                                       technology, petroleum and                                                                                              
                                       environmental sciences.                                                          Working to advance these
                                                                                                                        opportunities while ensuring public
                                       The PETROLEUM TECHNOLOGY                                                         safety are a host of organizations
                                       RESEARCH CENTRE (PTRC), located                                                  including the Canadian Food
                                       in the Regina Research Park, is one of                                           Inspection Agency, Toxicology
                                       the premiere petroleum research                                                                                                                                  Turning innovation into reality
                                                                                                                        Research Institute, Saskatchewan
                                       facilities in North America. PTRC is                                                                                                                             requires constant momentum. The
                                                                                                                        Food Processors Association,
                                       committed to helping companies                                                                                                                                   INDUSTRY LIAISON OFFICE (ILO)
                                                                                                                        Saskatchewan Health Research
                                       achieve clean and cost effective                                                                                                                                 on the U of S campus is the interface
                                                                                                                        Foundation, Saskatchewan Health
                                       technologies to meet the growing                                                                                                                                 between academic researchers and
                                                                              PRAIRIE PLANT SYSTEMS (PPS) is            Information Network, and the
                                       demand for oil with responsibility to                                                                                                                            the business community. Working
      Innovation Place                                                        one of those innovative start-up          Saskatchewan Drug Research
                                       the environment.                                                                                                                                                 with scientists, the ILO helps to pair
                                                                              companies. Established in 1988, PPS       Institute.                               The Food Centre helps clients
                                                                                                                                                                                                        research with industry by providing
  • Individual offices, labs and                                              began producing new small fruit                                                    determine the technical requirements
                                       Saskatchewan’s R&D capacity, in                                                                                                                                  the essential information necessary to
    other working areas along with                                            crops for western Canada using                                                     for manufacturing safe products and
                                       combination with one of the world’s biotechnology tools. Their expertise                                                                                         turn a concept into a business
    common areas, meeting rooms,                                                                                                                                 assists in modifying recipes while
                                       most generous national and                                                                                                                                       venture.
                                                                              expanded into the development of a                                                 maintaining quality standards and
    spacious gallerias and             provincial R&D tax credit systems,     wide range of plants - herbs,                                                      product characteristics. They help
    recreational facilities            has made this province home to         nutraceuticals, trees and grasses, as                                              clients from the planning stages       Financing is the ultimate key
  • Innovation Place Bio Processing    international corporations like Bayer  well as biopharmaceuticals. In a joint                                             through to a packaged and labelled     commercializing innovation. In
    Centre                             CropScience Inc., BASF Plant           venture with Hudson Bay Mining &                                                   product ready for test marketing.      addition to Saskatoon being cited as
  • L.F. Kristjanson Biotechnology     Sciences, and Dow AgroSciences.        Smelting Co. Ltd. of Flin Flon,                                                                                           #2 in Midwest North America in
    Complex houses fully automated                                            Manitoba, they established a growth                                                Industries like INFRAREADY             business cost competitiveness (KPMG
    growth chambers, 43                                                       chamber 365 metres below the              The SASKATCHEWAN FOOD                    PRODUCTS have benefited from this      2004), this province hosts numerable
    greenhouse compartments (500-                                             surface of the earth. Based on the        INDUSTRY DEVELOPMENT CENTRE              exceptional scientific cluster. A      funding programs contributing to
    1,000 ft2) and 9 furnished                                                success and security of their             supports the development and             home-grown company, InfraReady         investment solutions. Programs and
     laboratories (350-800 ft2)                                               underground facility, Health Canada       growth of a dynamic food processing      has become a prominent competitor      agencies like Foragen Technology
                                                                              awarded PPS a 5-year, $5.5 M              industry through its many programs       in the global marketplace for high     Ventures, the Agriculture                                                  contract for The Development of           and services aimed at food product       quality raw food ingredients, their    Development Fund (ADF), NRC-
                                                                              Comprehensive Operations for the          and process development,                 products offering reduced process      IRAP, or the Golden Opportunities
                                                                              Cultivation and Fabrication of            developing markets, quality              time, increased shelf stability,       Fund are a small sample of the
                                                                              Medicinal Marihuana.                      assurance and technology transfer.       improved product texture and natural   financing opportunities available.
A dynamic research community            organizations and companies since
needs champions, supporting and         1989. Hosting international missions,
promoting strong, vibrant, profitable   seminars, workshops and conferences,
bio-based industries. Organizations     Ag-West Bio fosters productive
like Ag-West Bio and the Saskatoon      relations among research, policy,
Regional Economic Development           business and financial professionals
Agency (SREDA) are those                (
                                        The SASKATOON REGIONAL
                                        ECONOMIC DEVELOPMENT
                                        AUTHORITY (SREDA) Inc. is dedicated
                                        to building the Saskatoon region
                                        economy by facilitating the expansion
                                        and/or retention of existing business,
                                        encouraging the location of
                                        complementary new business to the
                                        region, and improving related
                                        infrastructure and services to our local
                                        industry. SREDA proudly promotes
                                        Saskatoon as a great place to live,
Building Saskatchewan’s bio-            work, invest, and prosper
economy, AG-WEST BIO INC.               (
works with all stakeholders to
encourage the development of ideas
into commercial successes. Ag-West
Bio has seeded new initiatives and
accommodated expansion,
contributing approximately $9.9
million towards 53 projects in 43

Saskatchewan’s leaders in scientific research and discovery are setting the
national bedrock upon which tomorrow’s innovation can unfold.

Discover science and technology solutions as vast as the prairie horizon,
right here in Saskatchewan!

                                        This brochure was produced with
                                        funding from Saskatchewan Industry
                                        and Resources

                                        Photo credits:
Ag-West Bio Inc.
                                        Canadian Light Source Inc.
101 – 111 Research Drive
                                        NRC – Plant Biotechnology Institute
Saskatoon, SK S7N 3R2 CANADA            POS Pilot Plant Corp.
Tel: 306-975-1939                       Saskatchewan Agriculture and Food
Fax: 306-975-1966                       Saskatchewan Research Council
Email:              University of Saskatchewan
Web:                   Flax Council of Canada

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