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Respiratory units appear at the 16. th. week. Terminal Sac stage. 27. th ... Major surfactant is called lecithin. Second type of surfactant is called. sphingomyelin ...
RT-240 Pediatrics and Neonatology Class #1 Embryology Respiratory Therapy Program Allegany College of Maryland Cumberland, Maryland Terminology (Fertilization) Zygote Gametes Testes Ovaries Gametogenesis Spermatogenesis Oogenesis Fertilization Blastomeres Morula Erythroblast Embryo Amnion Yolk sac Trophoblast Placenta Chorion 1 Implantation of the Morula Endoderm GI, mouth, pharynx, lung and liver Ectoderm CNS, PNS, eyes, ears, nose, and appendages Mesoderm Connective tissue, cartilage, bone heart The embryo begins to grow! Intrauterine Life/Respiratory Development Two phases Embryonic Fetal Embryonic stage “primitive development stage” 1st five weeks of gestation Pseudoglandular stage 6th-16th weeks of gestation Dichotomous branching Intrauterine Life/Respiratory Development Canalicular stage 16th week -26th weeks Respiratory units appear at the 16th week Terminal Sac stage 27th week – 40 weeks Saccular 28-36 weeks Alveolar 36-term 2 Pulmonary Surfactant Major surfactant is called lecithin Second type of surfactant is called sphingomyelin Methyltransferase system 24 – 28 weeks Phosphocholine transferase system 35th week Amniocentesis Amniotic fluid is removed and analyzed… Chromosomal matching Lung maturity (l/s ratio) 1:1 90% RDS (Steroids) 2:1 5% RDS 1.5:1 50% RDS Gender Complications 3
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