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‘JOINT VENTURE OF GOVERNMENT OF GUJARAT AND THE GUJARAT CANCER SOCIETY’
GUJARAT CANCER & RESEARCH INSTITUTE
(M. P. SHAH CANCER HOSPITAL)
REGIONAL CANCER CENTRE
(Recognised by Ministry of Health & Family Welfare, Government of India)
MEMBER OF UICC
International Union Against Cancer (UICC)
ANNUAL REPORT
2007-2008
HON. DIRECTOR
DR. PANKAJ M. SHAH
HON. DEPUTY DIRECTORS
DR. RAJENDRA I. DAVE DR. KIRTI M. PATEL DR. SHILIN N. SHUKLA
HOSPITAL ADMINISTRATOR
SHRI NARENDRASINH T. CHAVDA
Civil Hospital Campus, Asarwa, Ahmedabad 380 016, Gujarat, INDIA
Tel: 079-22688000 (Hunting); Fax: 079-22685490
Website: www.cancerindia.org; E-Mail: gcriad1@sancharnet.in
The mission of the GCRI is to provide state-of-the art diagnostic and therapeutic services
to the patients of all types of origin and financial background suffering from cancer. Its
scope also encompasses registering the tumor burden in the population, prevention
through awareness drives, solving local medical problems through research and training of
medical students as well as imparting knowledge to the medical fraternity.
To fulfil the mission, GCRI
♦ Conducts OPD and indoor activities for diagnosis, staging, treatment and
monitoring disease progress.
♦ Renders free or subsidized treatment to needy patients without any distinction of
caste, creed or religion.
♦ Provides training to new generation of doctors as well as practicing fraternity.
♦ Offers unique experimental and research-oriented diagnosis and treatment
services to test new forms of diagnosis and therapy in order to improve quality of
life and expected survival of those afflicted with cancer.
♦ Organizes public education programmes, the diagnostic and blood donation
camps, conferences and other scientific meets.
♦ Displays a permanent Cancer Awareness and Anti-tobacco exhibition and arranges
other preventive efforts.
♦ Runs instruction based Hospice Centre, Home-Hospice Services and Rehabilitation
Service.
GCRI, with a multi-disciplinary close relationship between cancer care, research and
education, intends to provide the greatest hope to the patients and the general population
whose needs, we endeavour to cater to. It strives to see that fruits of modern science
reach up to the last man. GCRI believes that the world class cancer research, state of art
therapeutic efforts and intensive and extensive educational efforts regarding prevention,
detection, treatment and palliation in the field of cancer will improve the quality of life of all
those who suffer from it. GCRI collaboration believes that with other cancer organisations,
research laboratories and pharma-research establishments will bring a better tomorrow.
GCRI is dedicated to:
♦ Scientific attitude and humane approach to diagnosis and treatment of cancer.
♦ Inquisitiveness, innovation and creativity in the field of research and its translation
into day-to-day clinical applications.
♦ Value oriented as well as information and skill-intensive educational programmes.
♦ Respect to all schools of thoughts and endeavours for free exchange of ideas with
due acknowledgements of contributions by each member of GCRI.
♦ Simple, effective and targeted awareness programmes for prevention as well as
early detection of cancer and anti-tobacco drive directed at the medical profession
and population at large.
♦ Providing hope, sympathy and respect to all those who are terminally ill.
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TABLE OF CONTENTS
Group Departments & Other Information Page
I. PARA-CLINICAL A. Pathology 8
DEPARTMENTS A1- Histopathology, Cytology, Haematology, Biochemistry 8
A2- Blood Bank 10
A3- Microbiology 11
B. Radiodiagnosis 12
B1- Imaging Services 12
B2- Nuclear Medicine 13
II. CLINICAL C. Surgical Oncology 14
DEPARTMENTS C1- General Surgical Oncology 14
C2- Reconstructive (Plastic) Surgery 14
C3- Urosurgery 15
C4- Musculoskeletal Surgery 15
C5- Paediatric Surgery 15
C6- Neurosurgery 16
C7- Ophthalmology 16
C8 - Interventional Therapeutic Centre (IVTC) 17
D. Gynaecological Oncology 17
E. Medical Oncology 18
E1- Medical Oncology 18
E2 - Paediatric Oncology 19
E3 - Bone Marrow Transplant Service 20
E4 - Endocrinology 20
F. Anaesthesiology 21
G. Radiotherapy 22
H. Other Services 23
H1- Nursing Services 23
H2- Stoma Clinic 23
H3- Prosthesis and Rehabilitation Centre 24
H4- Physiotherapy 24
H5- Hospice Care and Home Hospice Service 25
H6- Pharmacy 25
H7- Administrative Services 25
III. CANCER I. Research Wing (Cancer Biology) 27
RESEARCH & I1- Cell Biology Division 27
EDUCATION I2- Molecular Endocrinology I & II 28
I3- Receptor and Growth Factor Lab 31
I4- Biochemistry Research Division 32
I5- Immunohistochemistry Division 33
I6- Medicinal Chemistry and Pharmaco Genomics 34
I7- Joint Activities - Silver Jubilee Celebration 35
J. Educational Activities 36
J1- Formal Educational Courses & List of P.G. Dissertations and PhD Thesis 36
J2- Complementary Training Programme to Formal Education 40
J3- Professional Training to Doctors and Scientists (Conferences, Workshops) 47
J4- Professional Training to Paramedics (Technological Courses) 48
J5- Community Education and Awareness Programmes 48
J6- Cancer Information Centre 48
J7- Staff Training – Intramural and Extramural 49
J8- Hospital Day – Research and Educational Aspects 50
J9- Clinical Meetings 51
J10 - Activities of the Scientific Research Committee 51
J11- GCS Research Bulletin 51
K. Library 51
L. Educational Graphics & Medical Photography 52
IV. COMMUNITY M. Cancer Epidemiology & Community Oncology 53
ONCOLOGY General Statistics of Registered Cases
N. Community Oncology Centre, Vasna 57
N1- Hospice Service 57
N2- Cancer Awareness & Anti-tobacco Exhibition 57
N3- Health Check-up Plan 57
N4- Development of Medicinal Plant Park 58
V. OUT- REACH O. Cancer Detection Camps, Blood Donation Camps, and Cancer Awareness Exhibition 59
ACTIVITIES P. Community Lectures by Staff 61
Q. Patient Care Evaluation Committee 63
VI. RESEARCH List of Projects, Publications and Presentations 64
ACTIVITIES
VII. INSTRUMENTS List of Instruments 101
VIII. ACCOUNTS Balance Sheet (2007-2008) 110
Academic Activities Initiated in Memory of Dr. T.B. Patel 135
1
From the Director’s Desk:
The Gujarat Cancer & Research Institute (GCRI) established in the year 1972, is a
functional autonomous body jointly managed by Government of Gujarat and Gujarat Cancer
Society. It is also a Regional Cancer Centre of Government of India and getting assistance under
National Cancer Control Programme. GCRI is a unique example of cooperation between State
Government, Central Government, and Non-Government Organization – Gujarat Cancer &
Research Institute. It is good and fortunate that Gujarat Cancer Society established in 1961 and is
instrumental in creating initial infrastructure of Cancer Hospital in Gujarat with the donation from
people of Gujarat. It is worth mentioning that Gujarat Cancer Society is blessed by His
Excellency, Governor of Gujarat. Today our Institute has attained the status of premier cancer
institute of the country and caters to patients from Gujarat, Rajasthan, Madhya Pradesh and
neighbouring State of Maharashtra.
The profile of the Institute presented in this report is the fruit of joints efforts of all staff
members of GCRI, Gujarat Cancer Society, Government of Gujarat and Government of India.
We have celebrated year 2007-2008 as Dr. T.B. Patel Centenary Year. We are all
fortunate that strong foundation laid by Founder Director Late Dr. T.B. Patel has resulted in an
internationally recognized Gujarat Cancer & Research Institute. Dr. T.B. Patel was associated
with Gujarat Cancer Society from its inception in 1961 under the leadership of the first Governor
of Gujarat Late Mehndi Navab Jung and the first Chief Minister of Gujarat, Dr. Jivraj Mehta. Dr.
T.B. Patel was pioneer in establishing cancer care activities in the State. It is a time to recall that
the future vision for cancer care conceived by Dr. T.B. Patel was supported by Late Dr. Jitendra
Mehta who motivated donors from all walks of life. Dr. T.B. Patel was instrumental in bringing
earmark donation from M.P. Shah Charitable Trust of London. Contribution of Late Dr. T.B. Patel
will be remembered at the Institute forever. We have included a small section mentioning the
academic activities initiated in the name of Late Dr. T.B. Patel – Dr. T.B. Patel Oration Award, Dr.
T.B. Patel Young Scientist Research Award, and Dr. T.B. Patel Travel Fellowship. Institute has
started Senior Citizen Ward for Geriatric cancer patients and conducted series of scientific events
during the year in his memory this year. Dr. T.B. Patel Drug Bank is working for helping poor
patients under the umbrella of Gujarat Cancer Society.
We are grateful to all members of Governing Board and GCRI-GCS Office Bearers for
their constant support.
Annual Report preparation was possible because of the untiring contribution by
committee headed by Dr. Shilin N. Shukla, Deputy Director (Research & Education Services).
th
I am happy to present the 36 Annual Report along with audited accounts of Gujarat Cancer &
Research Institute.
Dr. Pankaj M. Shah
Hon. Director
29th August, 2008
2
Diary of Activities of Dr. Pankaj M. Shah, Hon. Director, from 01.04.2007 to 31.03.2008
Date Event
13th Apr’07 Key Note Address at inaugural ceremony of Searoc Cancer Centre, Sony Cancer Hospital,
Jaipur, inaugurated by Hon’ble Chief Minister of Rajasthan Sushri Vijaya Raje Schindia
21st Apr’07 Tobacco Control and Cancer Awareness Programme, Diwan Ballubhai Secondary School,
Ahmedabad
26th Apr’07 National Advisory Committee on Technology in Oncology, New Delhi
29th Apr’07 Chaired session at National Meeting on CML, Bombay Hospital, Mumbai
1st May’07 Organised Workshop for Village Health Workers, Ahmedabad
2nd May’07 Honoured by Manav Bhushan Award by Shivanand Ashram, Ahmedabad
3rd May’07 Attended National Meeting on Telemedicine, ISRO, Ahmedabad
19th May’07 Chair Person for clinical session for Docetrez launch, Vadodara
20th May’07 Chief Guest at APA Annual Meeting and Morning Meeting with senior citizens for token fund
raised for Dr. TB Patel Senior Citizen Ward, Ahmedabad
24th May’07 Public Lecture on Understanding Cancer, Rotary Club Metropolitan, Ahmedabad
26th May’07 Tobacco De-addiction Youth Fare of Nareshwar Parivar, Nareshwar, Bharuch
th
29 May’07 Meeting of National Cancer Control Programme (NCCP), New Delhi
rd
3 June’07 Guest Lecture on Hormone Refractory Prostate Cancer at Conference on Prostate Cancer,
Muljibhai Hospital, Nadiad
7th June’07 Meeting with Superintendent and Dean of Civil Hospitals for NCCP Project alongwith
Mrs. Mona Khandhar, Joint Secretary Health, GOG, Ahmedabad
15th June’07 Workshop for Gynaecologists for Early Detection of Cancer in Women – for Doctors of UHC
and Chiranjivi Yojana, Ahmedabad, Ahmedabad
16th June’07 Inaugural address at Gujarat Head & Neck Oncology Conference, Ahmedabad
1st July’07 Chaired Breast Cancer Symposium, Ahmedabad
12th July’07 Indo-German Workshop Presentation - Epidemiology of Cervical Cancer in India,
Heidelberg, Germany
21st July’07 ASCO Presentations by GCRIans, Ahmedabad
23rd July’07 GCRI, GCS and AMC jointly started Shri Madanmohan Ramalal Urban Health Centre
inaugurated by Hon’ble Chief Minister Shri Narendrabhai Modi, Vasna, Ahmedabad
29th July’07 Cancer Update - Role of Family Physician in Cancer, IMA , Mehsana
24th Aug’07 Honoured by Excellence in Oncology Award by Ruby Hall Pune - Citation and 1 lac
cash received which is donated to GCS for Dr. TB Patel travel fellowship
26th Aug’07 Chaired the session at Lung Cancer Meeting, Amby Velly, Pune
14th Sep’07 Guest Lecture on Adjuvant CT in Colorectal Cancer, National Meeting of GI Surgeon,
Ahmedabad
22ndSep’07 Joint meeting for Retinoblastoma with Chennai Centre, Ahmedabad
24th Sep’07 Oraganised Bhajan Sandya by Shri Hemant Chauhan for ADCC Programme, Ahmedabad
27th Sep’07 Chief Guest at NIOH on Hindi Day, Ahmedabad
6th Oct’07 Chaired session at Lung Cancer Meet, Lonawala, Pune
14th Oct’07 Chaired session at Meeting of Haematology, Mumbai
21st Oct’07 Asian Oncology Meet, Hyderabad
28th Oct’07 Guest Lecture on Cancer Control Measures in India, Rajkot
17th Nov’07 Inauguration of Gujarat MP Radiation Oncologist Meet, Ahmedabad
18th Nov’07 Guest lecture on Targeted Therapy in Malignant Lymphoma, Indo American Lymphoma
Meet, Hyderabad
18th Dec’07 Inaugurated Trauma and Cancer Clinic, Sarvajanik Hospital, Modasa
19th Dec’07 Popular Science Lecture on Cancer at Science City, Ahmedabad
30th Dec’07 Chaired session at launch of Neudoxa by Zydus, Mumbai
11th Jan’08 Urooncology Meet, Ahmedabad Prostate Cancer Registry, Ahmedabad
7th Feb’08 National Adviser and Faculty at Asian Conference on Breast Cancer, New Delhi
2nd Mar’08 Chaired session on individualizing treatment in leukemia, Ahmedabad
12th Mar’08 Meeting Directors of RCC for 11th plan allotment for cancer, New Delhi
19th Mar’08 RCC Meeting, Goa
3
GCRI Profile At A Glance
GCRI - Speciality Hospital for Cancer
Regional Cancer Centre
650 indoor beds - Largest Cancer Hospital of the country
21,488 New Cases
2,12,813 Outdoor patients
20,187 Indoor admissions
12,01,809 Laboratory tests
98,929 Histologic examinations
72,843 Imaging and Radiological investigations
17,662 Major and Minor Surgeries
25,818 Chemotherapy Treatment
14,719 Radiation Treatment
GCRI - Speciality Medical Education Centre
DM - Medical Oncology : 4 students every year
MCh - Surgical Oncology : 4 students every year
MD – Pathology (3 students), Microbiology (1 student),
Radiodiagnosis (2 students), Gynaecological Oncology
(4 students) , Anaesthesiology (3 students), Radiotherapy
(2 students)
DMRE - Radiodiagnosis; DA - Anaesthesiology
DCP – Pathology; DGO - Gynaecological Oncology
Postgraduate Students – 69 Students
PhD - Life Sciences & Medical Microbiology - 9 Students
Dissertation Students of different universities - 31 Students
Diploma in Medical Laboratory Technologists – 50 Students
4
GCRI Profile At A Glance
GCRI - Research Organisation
7 well equipped Research Labs
51 on-going Research Projects; 19 Clinical Trials
Scientists are PhD Guides
Additional support from - National Cancer Institute (NCI),
USA/Germany/IARC/DST/DBT/CSIR/ICMR/
DAE/GSBTM/DMER/GUJCOST/GCS
Clinical Research hub for National and International drug trials
GCRI – Community Commitments
National Registry Programme - ICMR
Ahmedabad District Cancer Control Programme – Govt. of India
under NCCP
Gujarat Cancer Atlas Project - Govt. of Gujarat
Prevention of cancer – Anti-Tobacco drive
Early detection – Vasna Centre & Cancer Detection Camps
Hospice care; Home Hospice care
Helping hand to poor patients
Telepathology and Telemedicine projects
Patient Care Evaluation Committee; Oncology Training Centre
Sanskar Chowk (Entertainment and Education of Patients and
their Relatives)
Night Shelter for Patient’s Relatives
5
GCRI Profile At A Glance
GCRI Building 1
(Constructed by GCS)
Administrative Section/Pharmacy/Drug bank/Matron
Office/Educational Graphics & Medical Photography
st
1 Extension: Medical OPD/Day Care CT/ Pathology
collection/Store/Blood bank/ Minor OT/Endoscopy/OT complex/
ICCU/ IVTC/Male ward/Female ward
nd
2 Extension: Gynaec OPD/RMO Office/ Cash
collection/Radiology/Medical ward/ BMT/ Community
Oncology/Staff canteen
GCRI Building 2
(Constructed by GCS)
New OPD complex: Surgical OPD
Registration/Mandir/BMT/Board room
Nuclear Physics/Nuclear Medicine/ Isolation ward
Radiotherapy Building
Minimal care/Isolation/RT wards/Canteen
Research Building: Research labs/ Library/ Pathology/
Microbiology/ Cytology/ Immunohistochemistry/ Hostel
6
GCRI Profile At A Glance
GCRI Building 3
(Constructed by GCS)
Cama Hall/Guest House/MRI Building/
Physiotherapy/Prosthesis/Oncology Training Centre
Paediatric oncology 50 bedded hospital
PG Hostel
RMO quarters
Nursing/Technician’s quarters
Dhobi Ghat
GCRI HRD
Class I - 97
Class II - 37
Administrative Staff Class III – 79
Technical Staff Class III - 99
Nursing Staff - 278
Class IV – 294
Visiting Consultants - 56
Postgraduates Students - 69
Contract services- Security; Cleaning; Catering; Tailoring;
Laundry etc.
7
I. PARA-CLINICAL DEPARTMENTS
(A) DEPARTMENT OF PATHOLOGY
The Department of Pathology includes various services like Histopathology, Cytology,
Haematology, Biochemistry, Paediatric Oncology Haematology, Vasna Hospice Haematology,
Blood Bank, and Microbiology.
(A1) Histopathology, Cytology, Haematology, Biochemistry, Paediatric Oncology
Haematology and Vasna Hospice Haematology:
Staff Pattern: There are one Professor, two Associate Professors, three Assistant
Professors, six Junior Lecturers, four Fellows, nine Resident Doctors, five Biochemists and twenty
nine Laboratory Technicians.
Services: Pathology department is the heart of our Hospital; central to any cancer
management is tissue diagnosis. Metabolic profile and haematological alteration in a cancer
patient plays a pivotal role in overall outcome. The department is well equipped with highly
sophisticated microscopes attached with camera and computer for teaching and record purposes.
It provides services of histopathological diagnosis, frozen section diagnosis, haematological tests,
biochemical tests etc. The department has an internet facility for tele-pathology.
Service Output:
Histopathology Laboratory
No. Details of Work Done Number
1 Total Specimens 20994
2 Total Sections obtained 79731
3 Frozen Specimens 410
Cytology Laboratory
No. Details of Work Done Number
1 Fine Needle Aspiration Cytology 4812
2 Non-Gynaec Smears 2807
3 Gynaec Smears 4827
4 Outside/Camp Pap Smears 4350
Haematology Laboratory
No. Details of Work Done Number No. Details of Work Done Number
1 Haemoglobin 116638 13 RBC Count 112268
2 Total WBC Count 116638 14 Fluid Microscopy 1422
3 Differential Count 62133 15 LE Cell 168
4 Platelet Count 116638 16 Rheumatoid Arthritis Factor 370
5 Erythrocyte Sedimentation Rate 23230 17 Stickling Test 158
6 Urine analysis 49364 18 Sucrose Lysis Test 236
7 Urine Bile Salt / Bile Pigment 4934 19 CSF Microscopy 1819
8 Malarial Parasite 9536 20 Fibrinogen Degradation 429
Product
9 Activated Partial Thromboplastin 26521 21 Prothrombin Time 26521
10 Glucose-6-Phosphate 300 22 Osmotic Fragility Test 302
Dehydrogenase
11 Fetal Haemoglobin 150 23 Stool Test 5203
12 Reticulocyte Count 1628 24 Plasma Fibrinogen 639
8
Biochemistry Laboratory
No. Details of Work Done Number No. Details of Work Done Number
1 Blood Sugar 29822 19 S. Calcium 1822
2 Blood Urea Nitrogen 34256 20 S. Phosphorus 1516
3 Creatinine 33028 21 S. Amylase 32
4 Sodium 24613 22 S. Acetone 24
5 Potassium 24613 23 Urine for Urobilinogen 8
6 Chloride 24288 24 BJ Protein 38
7 S. Alkaline Phosphatase 31062 25 24 hours Urinary Protein 24
8 SGOT (Transaminase) 29672 26 CSF 832
9 SGPT (Transaminase) 29977 27 Plasma Fibrinogen -
10 S. Total Protein 27432 28 S. Magnesium 2538
11 S. Albumin 27829 29 S. Triglyceride 4864
12 S. Globulin 27430 30 S. HDL Cholesterol 4864
13 S. Bilirubin (Total) 26870 31 S. VLDL Cholesterol 4810
14 S. Bilirubin (Direct) 26870 32 S. LDL Cholesterol 4810
15 S. Bilirubin (Indirect) 26870 33 S. IgA 170
16 S. Acid Protease 753 34 S. IgG 170
17 S. Uric Acid 9031 35 S. IgM 170
18 S. Cholesterol 4945
Activities: Clinical: The department of Pathology conducts blood collections for special
investigations at Out Patients’ Department (OPD) at the hospital especially for early detection of
pre-invasive and invasive malignancy. Pap Smear Tests and Serological Tests are performed
free of charge and biopsies are taken at nominal charge. The department also examines and
gives expert opinion for the outside biopsies and specimens, and also performs
immunohistochemistry tests thereon. The outdoor Blood Donation Camps are conducted at
various places in Gujarat. The department also actively participates in GCRI academic meetings.
Academic: Practical/Theory training to post-graduate students/doctors for MD and DCP
Degrees. Practical/Theory training of routine laboratory investigations to students for Diploma in
Medical Laboratory Technologists Course is also given by the department.
Research: Maintenance of patient’s record and statistical data analysis is done.
Conference Organised: The department has organised CME on Surgical Pathology –
2007 and Launching of Gujarat Cancer Atlas Project on September 8, 2007. Total 150 delegates
have attended the conference. The faculties were Dr. Dipen Maru (USA), Dr. Nirag Jhala (USA),
and Dr. Geeta Chackoo. Dr. Priti Trivedi was the Organising Secretary and Co-Secretary was
Dr. Dhaval Jetly. International Cytology Conference, through Video Conferencing was arranged
on February 8-9, 2008 under the banner of Tata Memorial Hospital, Mumbai, and GCRI. Total 50
delegates have attended the video conferencing.
Complementary Training Programme:
No. Programme Students
1 Observership 15
2 MD 7
9
(A2) Blood Bank
Staff Pattern: This division works within the Department of Pathology. There are one
Blood Transfusion Officer, two Medical Officers, four Senior Laboratory Technicians and four
Junior Laboratory Technicians.
Services: Division of Transfusion Medicine collects blood from voluntary as well as
replacement donors in the hospital and outside the hospital by arranging the outdoor blood
donation camps. All the serological tests mandatory by the Food and Drug Control Administration
(FDA) like HBsAg, HIV, HCV, VDRL and malaria are done with collected blood units.
Service Output:
No. Details of Work Done Number
1 Blood Banking
Blood tapping 14513
Replacement donors 11449
Voluntary donors 3064
Out door camps 87
Transfusion 30137
Blood Transfusion 1935
PCV (Packed Red Cell) 12314
PRP (Platelet Rich Plasma) 9156
FFP (Fresh Frozen Plasma) 6199
Single donor platelet 533
Autologous & Allogenic Bone Marrow Collection 8
2 Tests For Patients For Donors
Blood Groups 9928 14513
Coomb's Test - 183
D'U' test for weak antigen - 852
HBsAg 23771 14513
HIV 23771 14513
HCV - 1123
VDRL - 14313
Malarial parasite - 14313
Activities: Clinical: The division does blood grouping of donors and patients, and
supply the blood after cross-matching to the patients. Three components of blood like PCV, PRP
and FFP are separated with modern equipments and supply to the patients according to their
requirements. Different Apheresis procedures like Platelet pheresis and Therapeutic Apheresis
with the help of Cell Separator Equipment are being done. PBSC collection (Peripheral Blood
Stem Cell) is also done. The division is well equipped with all the modern equipments like Gel
Technology, Cross-Matching, Cell Separator Procedures, Blood Irradiation and Equipment of
Leukodepletion of Components.
Academic: The department is actively involved by giving practical/theory training related
to transfusion medicine to students for Medical Laboratory Technology Course. DNB Students
from the Prathma Blood Centre are coming for training under Dr. Jayshree Shukla. Doctors and
Technicians from Gujarat are also coming frequently for training of component separation and
apheresis procedures.
Professional Contribution and Recognition: Dr. Jayshree Shukla, Blood Transfusion
Officer and Dr. Tarak Patel, Medical Officer, have been invited for giving training to Medical
Officers and Technicians in Training Programme conducted by NACO, Ahmedabad.
10
Public Services: The department performs apheresis procedure and irradiation of the
blood components for patients coming outside the Hospital.
(A3) Microbiology
Staff Pattern: There is one Professor, one Fellow, one Resident Doctor, one PhD
student, one Biochemist and two Senior Laboratory Technicians in the department.
Services: This department looks after the diagnosis of infectious diseases complicating
cancer involving bacteria, fungi, serodiagnosis of viral diseases, and molecular diagnosis of the
infection in patients. It also caters to bring out guidelines for prevention of hospital acquired
infection, performs periodical surveillance and conducts frequent training programme for nursing
staff.
Service Output:
No. Details of Work Done Number
1 Culture and Antibiotic Susceptibility
Aerobic 2272
Anaerobic -
Fungal 2223
Blood 1549
H. Pylori 80
2 Microscopy
Sp. Gram Stain 80
Z. N. Stain 584
Pneumocystis Carinii Stain 05
3 Serology
Widal Test 131
VDRL Test 17
CMV Test 104
HSV Test 64
HBeAg & Anti- HBeAg 397
C-reactive Protein 20
Activities: Clinical: The department is mainly concerned with clinical diagnostic and
cancer related diagnostic and research work. As far as the diagnostic work is concerned, patients
referred by surgical oncology / medical oncology / paediatric oncology / BMT units /
gynaecological oncology / neurooncology / urooncology / radiotherapy departments and OPD’s
are screened for infection, identification and sensitivity tests, and diagnosis of particular infection
by various tests. The tests performed during the year April 2007 to March 2008 are shown in the
above table. Routine day-to-day laboratory diagnostic culture methods of all clinical samples are
performed. Serological diagnosis of different infectious diseases is performed.
No. Ward/ Unit /OT/ Instrument Surveillance Programme conducted
1 New BMT 2
2 Old BMT 3
3 Main OT 3
4 Pathology A/C Machine 2
5 Chemical testing 2
6 ICU 1
7 Paediatric Leukemia Cabins 1
11
Academic: This year one student joined MD course under guide ship of Dr. Parijath
Goswami. On following topics: rapid diagnosis in infectious diseases, identification of bacteria,
different stains of bacteria, fungi and parasites, urinary tract infection, drug resistance, lectures
were conducted for PG students.
Research: Detection of high and low risk Human Papilloma Virus subtypes prevalent in
cancerous and non-cancerous lesions of the uterine cervix in Indian women.
Professional Contribution and Recognition: Dr. Parijath Goswami, Professor,
contributed as a Judge of Science in fun at Vikram Sarabhai Community Science Centre on
October 2007. She has also contributed as a Technical expert of scrutiny of kits at Gujarat State
AIDS Control Society in October 2007.
Conference Organised: Dr. Parijath Goswami, Professor, and her team organised
International Standards for Infection Prevention focusing on Surgery Related Infections under the
banner of GC & RI and HIS – Gujarat Chapter on October 7, 2007. Total 175 delegates and 6
faculties participated in the programme. The CME was inaugurated by Dr. NB Dholakia, Director,
CMSO, Gandhinagar. Other dignitaries present were Dr. Bharat Gadhavi and Dr. Manjul
Joshipura. At the time of inauguration the first News Letter of HIS-India, Guajart Chapter was
released.
Complementary Training Programme:
No. Programme Students
1 MD 1
2 PhD 1
(B) DEPARTMENT OF RADIODIAGNOSIS
(B1) Imaging Services
Staff Pattern: The department is served with one Professor, three Associate Professors,
two Assistant Professors, one Junior Lecturer, one Visiting Radiologist, ten Residents, twenty
three Radiographers, Technicians and Dark Room Assistants.
Services: The Department is fully equipped with 500 MA Siemens X-ray units, OPG
machine-Siemens, Siemens Seroscope-DSA Machine, Siemens IITV guidance Fluoroscopy
machine, Mammomat-Mammography machine, Logic 200 Pro-series USG machine, GE
Advantage II–USG machine, Logic alfa 100-Portable USG machine, Siemens G-50–Doppler
Machine, Fuji CR system, ISSA- Department networking and data storage system, CT W2000
Spiral CT scanner Hitachi, Seimens 6 Slices (Emotion) CT scan and 0.4Tesla Hitachi Aperto MRI
Machine.
Service Output:
No. Procedure Number No. Procedure Number
1 X-Ray 44307 8 USG Guided Biopsy 1899
2 Intravenous pyelography 241 9 CT Guided Biopsy 717
3 Ultrasonography (USG) 16810 10 Angiography + Embolization 7
4 CT SCAN 9059 11 PT BD / PCN 34
5 Mammography 2731 12 Magnetic Resonance Imaging 1664
(MRI)
6 Barium Swallow & Meal 3391 13 Colour Doppler 1584
7 Barium Enema 12
Activities: Clinical: The department of Radiodiagnosis conducts radiological part of
health checkup programme at COC, Vasna. X-ray, Mammography and Ultrasonography are
12
performed at cheaper rates, for early detection of pathology. Department also support
radiological part in various camps and health checkup programme managed by institute. The
department also participates in GCRI academic meetings.
Academic: Regular lectures, case presentation, journal presentation, and interesting
case discussion conducted for resident doctors in the department.
Research: The department maintains patient’s data and images, and generates statistical
data and studies which are presented in national and international conferences.
Public Services: The department is conducting radiological investigations of health
check-up programme, being conducted at COC, Vasna. We are also conducting radiological part
of IAS Officers health checkup programme and finalizing IAS health check up reports at our
department.
Complementary Training Programme:
No. Programme Students
1 DMRE 4
2 MD 6
3 Observership 19
(B2) Nuclear Medicine
Staff Pattern: The department has one Professor, one Medical Officer, one Nuclear
Health Physicist and four Technologists.
Services: The department is well equipped with instruments like Gamma Camera (GE
Infinia, Siemen’s Dicom), two dose calibrators, survey meter, surface contamination monitor, L-
bench, thyroid uptake system, two fume hood (one in radiopharmacy other in iodine therapy
ward), decontamination kit, lead lined decay drum and four lead barrier for I-131 therapy ward.
There is one new instrument Dual Head Gamma Camera (GE Infinia).
Service Output:
No. Details of Work Done Number No. Details of Work Done Number
1 Bone scan 1843 8 Large dose therapy 52
2 Renal scan (DTPA, MAG-3 605 9 Bone SPECT 10
& DMSA)
99m
3 Meckel study 2 10 TC04 thyroid scan 394
4 DMSA (V) scan 2 11 ECD brain SPECT 5
5 IDA hepato biliary scan 6 12 MIBI scan for cardiac and tumor 2
imaging
6 Transplant study 2 13 Scintimammography 2
7 Thyrotoxicosis therapy 50 14 Sr-89 therapy 6
13
II. CLINICAL DEPARTMENTS
(C) DEPARTMENT OF SURGICAL ONCOLOGY
There are five Surgical Oncology Units (C1) and 6 Superspeciality Oncology Units (C2-
C8), which are as follows: Reconstructive (Plastic) surgery (C2), Urosurgery (C3),
Musculoskeletal surgery (C4), Paediatric surgery (C5), Neurosurgery (C6), and Ophthalmology
(C7). The department also runs the Interventional Therapy Centre (C8).
(C1) General Surgical Oncology
Staff Pattern: There are five Surgical Units. Each Surgical Unit has one Professor, one
Associate Professor, three Residents, and one or two Fellows.
Services: The department offers services in diagnosis, treatment, and palliative care of
the patients. Different surgical teams occupy five major surgical operation theatres. Day stay unit
facilities are provided for biopsy and evaluation of lesion before planning of surgery. The
department is involved in perioperative care, follow up and care of terminally ill patients.
Service Output:
No. Details of Work Done Number
1 Major surgeries 4164
2 Minor surgeries 9650
3 Endoscopy procedures 8946
Activities: Clinical: Camps for early detection of cancer are conducted at various places
in Gujarat and the neighbouring states, including organisations such as ONGC, Air Force and
Armed Forces etc. Total 38 camps have been organised at various places in this year. The
department also participates in GCRI academic meetings.
Academic: Regular lectures and teaching programmes are conducted for Resident
Doctors and Fellows in the department.
Research: Maintenance of patient’s records and statistical data analysis is done. The
data is presented in national level conferences and published in national/ international journals.
Professional Contribution and Recognition: The department received Vimla Agarwal
Trophy for maximum research paper publications during the year 2007-2008.
Dr. Rajendra Dave, Deputy Director (Surgical Services) was awarded Motilal Patel
Oration Award in November 2007. He was also awarded with Col. Brig (Dr. Ganguly) Award by
Association of Surgeons of India in 2008.
Dr. Kiran Kothari, Professor, was elected as Governing Council Member of Indian
Association of Surgical Oncology for the years 2007-2009. He was invited for Guest Lectures on
‘Where do we stand in MIS for GI Cancer’ and ‘Role of MIS in Colorectal Cancer Surgery’ during
the Golden Jubilee Celebration of Chittranjan Cancer Centre, Kolkata, on November 3-4, 2007.
Dr. Rajen Tankshali, Professor was elected as Executive Committee Member of Indian
Association of Surgical Oncology for the years 2007-2009.
Dr. Rohan Vinayak, Resident, won KS Gopinath Oncoquiz in IASO Conference in
September 2007.
Complementary Training Programme:
No. Programme Students
1 MCh 12
(C2) Reconstructive (Plastic) Surgery
Staff Pattern: This service is run with the help of three Visiting Plastic Surgeons.
Services: Apart from attending OPD once a week, reconstructive surgeries are done in
main operation theatre twice per week. Reconstructive Surgeries for head and neck cancer
14
patients and CFRs with the help of neurosurgeons are done. Screening of patients requiring
prosthesis is done in OPD and they are guided about the artificial limbs and body parts.
Service Output:
No. Details of Work Done Number
1 Skull base surgery 48
2 Flaps 635
Public Services: The department offers services to the patients from all over Gujarat who
require reconstruction of lost body parts and guides them about prosthesis.
(C3) Urosurgery
Staff Pattern: This service is run with the help of three Visiting Urology Surgeons and
one Fellow.
Services: The department offers services in OPD, operation theatre and day stay unit,
twice per week. They examine, investigate, and treat patients of urogenital cancer.
Service Output:
No. Details of Work Done Number
1 Major Surgeries 128
2 Minor Surgeries 222
Activities: Academic: The department is actively involved in teaching programme of
MCh students.
(C4) Musculoskeletal Surgery
Staff Pattern: Two Senior and two Assistant Visiting Orthopaedic Surgeons are providing
their services.
Services: It has two OPD days in a week. The operation theatre of Musculoskeletal
Oncology is well equipped with ultra-modern instruments and equipments like oscillating saw,
oscillating drill, universal assimilating drill, laminar air flow, radiolucent operation theatre table with
all necessary attachments, Image Intensifier Television (IITV), etc.
Service Output:
No. Details of Work Done Number
1 Major Surgeries 150
Limb salvage of primary bone tumour (malignant) 74
Curettage for benign bone tumours 28
Amputations 36
Palliative fixation for metastatic skeletal disease 12
2 Minor diagnostic procedure (biopsy) 228
(C5) Paediatric Surgery
Staff Pattern: Three Visiting Paediatric Surgeons run the service.
Services: The department offers its services to paediatric OPD, Day Stay Unit and
operation theatre for treatment of paediatric cancer patients. The department does the procedure
of Hickman catheterisation, a very important central catheter, for paediatric patients. The
procedure is done under radiological guidance.
No. Details of Work Done Number
1 OPD Cases 626
2 Major and Minor Surgeries 37
3 Hickman’s Catheter Insertion 83
15
(C6) Neurosurgery
Staff Pattern: The department has three Neurosurgeons and three Medical Officers.
Services: The department is well equipped with two operation theatres. The operation
theatre is well equipped with Laminar Air Flow and state of the art anaesthesia system by British
Oxygen Company, Microscope with C.C.T.V. by Zeiss, Ultrasonic Surgical Aspirator by Valley
Lab, Modern Diathermy Generator by Valley Lab and Bovi, C-Arm with DSA facilities, Operation
table with remote control, Radio Frequency Lesion Generator, Intensive Care facilities with state
of the art cardio respiratory monitoring system and its own dedicated Central Sterile Supply
Department.
Service Output:
No. Details of Work Done Number
1 Brain Tumor, Infection, Vascular Malformation, Craniovertebral 482
Anomaly, Skull Base Tumors, Spinal Tumours
2 STB (CRW Frame), STB (Komai Frame) 67
3 Stereotactic Craniotomy 7
4 Posterior Fossa Surgery 59
5 Lateral Ventricle Tumors 1
6 Transphenoidal Approach 13
rd
7 3 Ventricle Tumour 2
Activities: The department is running OPD on Monday and Thursday every week where
new patients are examined and the follow up patients are regularly attended in the OPD. The
indoor references are regularly attended. The services to the poor patients for neurosurgical
diseases are offered. The department also provides emergency services to the patients. The
regular teaching to the Medical Officers and Research Fellow is carried out during the ward round
and operation. The clinical meeting of the institute is being regularly attended by all the medical
staff and the presentations are made in the clinical meeting as per the schedule. All the medical
staff remain update with reading of the standard neurosurgical text books and the journals at the
library. The department is also having interactions with other departments of the hospital e.g.
Surgical Oncology, Reconstructive (Plastic) Surgery, Medical Oncology, Endocrinology,
Biochemistry, Pathology, Radiotherapy, Radiodiagnosis, and Physiotherapy. The medical staff is
regularly presenting the clinical research paper at the national and international conferences.
There is also potential to start DNB courses in the speciality of Neurosurgery at the institute.
Public Services: The department has participated in the programme of tobacco de-
addiction being carried out at the Institute.
(C7) Ophthalmology
Staff Pattern: One Visiting Ophthalmologist runs the service.
Services: The department offers services in OPD, operation theatre and day stay unit,
twice per week. They examine, investigate and treat patients of urogenital cancer.
Service Output:
No. Details of Work Done Number
1 Cases seen 126
2 Surgeries - Ennucleation 16
Activities: Retinoblastoma tumor board initiation along with paediatric oncologists,
radiation oncologists, pathologists and consultants from M & S Institute of Ophthalmology (for
laser biopsy of retinoblastoma cases).
16
(C8) Interventional Therapeutic Centre (IVTC)
Staff Pattern: There are one Associate Professor and three Visiting Surgeons in the
department.
Services: Routine diagnostic and therapeutic upper and lower Gastrointestinal
Endoscopy is performed. For diagnosis, biopsies are taken to know the nature of disease.
Therapeutic procedures like dilatation of oesophagus, endoprosthesis, stoppage of haemorrhage,
common bile duct (CBD) stenting, stone extraction, polypectomy, central nervous catheterisation
(CVC), Percutaneous Endoscopic Gastrostomy (PEG) etc. are performed. Also, flexible
diagnostic as well as therapeutic bronchoscopies are carried out for diagnosis of lung diseases.
Service Output:
No. Details of Work Done Number
1 Gastroscopy 2321
2 Endoscopic Retrograde Choledocopancreatography (ERCP) 104
3 Bronchoscopy 447
4 Colonoscopy 495
5 PEG 5
6 Endoprosthesis 26
7 Dilatation 341
Activities: Training of Gastrointestinal Endoscopy procedures is being given to Resident
Doctors of Civil Hospital, Ahmedabad.
(D) DEPARTMENT OF GYNAECOLOGICAL ONCOLOGY
Staff Pattern: There are one honorary Visiting Gynaecologist, one Professor, two
practicing full time additional Professors, two Associate Professors, two Assistant Professors, two
Junior Lecturers and three Fellows.
Services: The department offers services in following areas (1) Well Woman Clinic for
early detection of gynaecological malignancies, especially Pap smears for cervical cancer, (2)
Colposcopy Clinic Referral Centre for pre-invasive cervical cancer. Colposcopies are performed
and directed biopsies taken, (3) Conservative management of pre-invasive cervical cancer by
Large Loop Excision of the Transformation Zone (LLETZ), (4) Referral Centre for diagnosis and
management of all premalignant and invasive gynaecological malignancies such as cervical
cancer, trophoblastic disease, ovarian tumors, vulvar cancer, endometrial cancer etc.
Service Output:
No. Details of Work Done Number
1 Radical Hysterectomy + Bilateral Pelvic Lymph Node Dissection 87
2 Laparotomy for Ovarian Tumours 156
3 Staging Laparotomy for Endometrial Cancer 34
4 Radical Vulvectomy + Groin Dissection 17
5 Other Major Surgeries 64
6 Minor surgical procedures 550
7 Colposcopies 849
Activities: Clinical: The gynaecological department conducts a well woman clinic daily at
the hospital especially for early detection of pre-invasive and invasive cervical malignancy. Pap
smears and Colposcopy are performed free of charge and biopsies are taken at nominal charge.
Camps for early detection are conducted at various places in Gujarat and the neighbouring states,
including organisations such as ONGC, Air Force, and Armed Forces etc. Total 38 camps are
done at various places in this year. Also, participates in GC & RI clinical meetings.
17
Academic: Regular lectures and teaching programme conducted for resident doctors.
Research: Maintenance of all records, data and statistics of the department. Study of
various cases / articles for presentations and publications is also done.
Professional Contribution and Recognition: Dr. Kalpana Dave, Professor and Head,
has participated in ‘Hello Doctor’ at DD1 channel on Doordarshan regarding public awareness for
cancer in January 2008. She has also participated in ALL INDIA Radio Programme regarding
gynaecological cancer in February 2008. She has also participated in In-Cable TV channel on
endometrial cancer and role of fat consumption in March 2008. She has taken special training at
TMH, Mumbai, for Rural Cancer Control Programme on May 14-15, 2007.
Dr. Ava Desai, Additional Professor, was elected as President of Association of
Gynaecological Oncologists of India for the year 2007.
Dr. Meeta Mankad, Additional Professor, got best presentation award for Apani Bat
(Audio Visual Presentation addressing the patients and relatives) on Hospital Day Celebration on
April 7, 2007
Dr. Pariseema Dave, Associate Professor, was the Managing Committee Member of
Association of Gynaecological Oncologists of India for the year 2007.
Dr. Anjana Chauhan, Assistant Professor, recieved Dr. TB Patel Silver Medal (Young
Scientist) for oral paper presentation during Hospital Day Celebration on April 19, 2008.
Dr. Apoorva Gupta, Resident, was awarded ‘Indumati Jhaveri Award’ for best paper
presentation for the topic ‘Vaginal delivery of breech, still a role after Hannah trial - A study of 361
patients’ at FOGSI Conference, Calcutta, 2007. He also won runner-up prize in Quiz on
Obstetrics PPH at Yuva FOGSI, Ahmedabad, 2007.
Public Services: Camps for cervical cancer screening organised at various places and
also under district cancer control programmes. Thirteen camps were organised at Victoria Jubilee,
Ahmedabad, and about 28 patients attended the same. During the year, total 4228 Pap’s Smears
taken of which 2088 from Ahmedabad, 1443 from rural area and 697 from urban area.
Conference Organised: The department has organised Workshop on Common Cancer
of Women for doctors of Chiranjeevi Yojna and Gynaecologists of Ahmedabad on June 15, 2007.
The department has also organised Workshop on Common Cancer of Women for gynaecologists
of district hospitals of Gujarat and doctors of urban health centres of Ahmedabad Municipal
Corporation on January 11, 2008.
Complementary Training Programme:
No. Programme Students
1 Observership 2
2 Fellowship 6
3 Dissertation 8
4 Project work 3
(E) DEPARTMENT OF MEDICAL ONCOLOGY
(E1) Medical Oncology
Staff Pattern: There are three Professors, one Additional Professor, two Associate
Professors, four Assistant Professors, one Junior Lecturer, three Medical Officers and twelve
Resident Doctors. The clinical trial wing has two Medical Officers, three Data Managers and one
Nursing Assistant.
Services: The department of the Medical Oncology includes the services to adult
patients.
18
Service Output:
No. Details of Work Done Number
1 New and refer cases 7062
2 Follow-up cases 42183
3 Day care chemo administration 22037
4 Minor operation procedures
Bone marrow aspiration/biopsy (adult) 3462
Others 3026
Activities: Clinical: There are about 100 bedded indoor facilities for adult oncology.
Academic: The department runs DM Course with active training for DM Residents (4 per
year - total 12 Residents); discussion of clinical topic and case presentation by DM resident
everyday, Telemedicine conference with discussion of topic with RCC Trivendrum and Tata
Memorial Hospital.
Research: The department has undertaken research projects supported by GCS, ICMR,
and Pharma companies.
Professional Contribution and Recognition: Dr. Pankaj Shah, Hon. Director,
honoured by ‘Excellence in Oncology Award’ by Ruby Hall, Pune, on August 24, 2007. He
delivered a key note address at inauguration of Sony Cancer Hospital, Jaipur, on April 13, 2007.
He presented 'Epidemiology of Cervical Cancer in India' as a part of Indo-German Workshop at
Heidelberg, Germany.
Dr. Kirti Patel, Hon. Deputy Director (Medical Services) and Professor, awarded two
orations Dr. Minda Oration and Dr. Pranlal Mehta Oration at IMA GSB for the year 2007-2008.
Dr. Shilin Shukla, Hon. Deputy Director (Research and Education Services) and
Professor, has studied and passed Postgraduate Diploma in Health Care and Hospital
Management from IGNOU. He has revised book on Cancer in Gujarati, which consists of 408
pages. He was invited as a Chairperson in the Global Conference in Medical Oncology held at
Hyderabad. He has also given a keynote address in the national conference of Indian Association
for Cancer Research. He has participated in ‘Hello Doctor’ at DD1 channel on Doordarshan
regarding public awareness for cancer in January 2008 and also participated in ALL INDIA Radio
Programme regarding cancer in February 2008.
Dr. Bharat Parikh, Professor, is editorial board member of Indian Journal of Medical &
Paediatric Oncology. He is also Executive Committee Member of Indian Co-Operative Network
(ICON). He was Organising Committee Member for various GCRI-GCS Public Events.
Dr. Apurva Patel, Assistant Professor, is representative of Central Zone, Gujarat State.
Dr. Sonia Parikh, Assistant Professor, has given a lecture on 'Factor G in cancer-
Importance of predictive Diagnostics' for GenDioT training programme on genetic diagnosis
organised by Gujarat State Biotechnology Mission in December 2007.
Public Services: The department has organised public awareness camps and early
detection camps at various places of Gujarat.
Conference Organised: The department participated in Post ASCO Highlights 2007 on
July 21 and 28, 2007, and Clinical Excellence Programme on July 31, 2007.
Complementary Training Programme:
No. Programme Students
1 DM 12
(E2) Paediatric Oncology
Staff Pattern: The doctors of Medical Oncology cater their services to paediatric
oncology.
19
Services: The department of the Medical Oncology provides services to paediatric
patients. The paediatric surgery is done by three Paediatric Surgeons mentioned in C5.
Service Output:
No. Details of Work Done Number
1 New and refer cases 684
2 Follow-up cases 10546
3 Day care chemo administration 5227
4 Minor operation procedures 1339
5 Others 2723
Activities: Clinical: There are about 50 bedded indoor facilities at Paediatric Oncology
Centre.
Conference Organised: The department has organised CME on Retinoblastoma on
September 22, 2007.
(E3) Bone Marrow Transplant Service
Staff Pattern: Bone Marrow Transplant Service is run by doctors of Medical Oncology.
Services: The department of the Medical Oncology provides service to Bone Marrow
Transplant patients.
Service Output:
No. Details of Work Done Number
1 Total BMT 13
BMT-Allogenic 10
Acute Myeloid Leukemia 03
Acute Lymphoid Leukemia 01
Chronic Myeloid Leukemia 01
Aplastic Anaemia 01
Thalassemia Major 04
BMT-Autologous 02
Hodgkin’s Disease 01
Multiple Myeloma 01
Umbilical cord stem cell transplantation 01
Thalassemia Major 01
Activities: Clinical: This unit carries out management of acute leukemia and
immunocompromised patients at the special sterile isolated leukemia ward on the medical floor.
(E4) Endocrinology
Staff Pattern: Three Visiting Consultant Endocrinologists and one Visiting Physician run
the service.
Services: This department is actively involved in clinical diagnosis, treatment and regular
follow-up of diabetes, thyroid disorders, pituitary related dysfunction and other hormone
abnormalities. Follow-up and new cases are seen quarterly in a week on Monday, Tuesday,
Thursday, and Friday.
20
Service Output:
No. Details of Work Done Number
1 New Cases 451
2 Thyroid Dysfunction 1971
3 Diabetes 902
4 Pituitary Adenoma 82
5 Growth Hormone (GH) Deficiency 252
6 Cushing Syndrome 11
7 Others 426
(F) DEPARTMENT OF ANAESTHESIOLOGY
Staff Pattern: There are two Professors, three Associate Professors, four Assistant
Professors, eight Junior Lecturers, one Medical Officer, fourteen Resident Doctors and two
Theater Technicians in the department.
Services: The department offers services of anaesthesia for surgical patients. It provides
services during peri-operative period, which includes pre-anaesthetic check up and anaesthesia
fitness, intra-operative management and post-operative care of the patients. These services are
provided for all major and minor surgical procedures, gynaecological surgeries, neurological
surgeries and day stay surgeries. Anaesthesia department also gives services for either providing
anaesthesia or providing only monitoring care for radiotherapy patients, patients undergoing
radiological procedures, invasive procedures in IVTC or CT scan. The department provides
emergency services in all the wards for central / peripheral venous access and resuscitation of
the patient. Pain clinic services are offered by the department for all suffering from chronic cancer
pain. Under these services, various nerve blocks are given. Thus department of anaesthesia
plays a key role in providing overall care of the patients in peri-operative period, intensive care for
critical illness and pain relief and palliative care during terminal illness of the patients.
Service Output:
No. Details of Work Done Number
1 Elective + Emergency surgeries Main OT 3161
2 Elective + Emergency surgeries OT 7 266
3 Elective + Emergency surgeries Neuro OT 476
4 Day Stay Unit 10483
5 Pain Clinic 298
6 CT Scan + MRI + USG Guided Biopsy 354
7 Intra Cavitory Radium + Implant under anaesthesia 865
8 Radiotherapy in pediatric patients under anaesthesia 712
9 Interventional Therapy under anaesthesia 28
Activities: Clinical: Department is involved in all types of surgical procedures done
under anaesthesia, in cancer patients. It includes all types of elective major cancer surgeries,
minor Day Stay procedures like biopsies, emergency surgeries, and post operative and ICU care
of the patients. Different super specialties like plastic surgeries, musculo-skeletal surgeries,
urological surgeries, gynaecological surgeries etc. are involved in treatment of cancer. Our
department provides anaesthesia or monitored anaesthesia care as per the requirement of the
patient and surgeons. Neuro-oncology department is unique feature in our institute. Hence, we
have experience of conducting anaesthesia for neurosurgical procedures as well. Our department
takes lead in peripheral venous access as well as central venous access as per requirement in
the patient. All emergency calls for resuscitation, Ryle’s tube insertion, monitored anaesthesia
21
and venous access are attended by the departmental staff. We also take care of all patients
admitted in ICU, medical ICU and neuro ICU.
Academic: Our department is recognised for post graduation studies in anaesthesia. PG
students are given dissertation topics and are guided to carry out research and prepare their
dissertation. Regular seminars and lectures are held for post graduate students. They are also
taught the practical aspect of the subject during routine theater work. They are encouraged to
participate in various conferences, seminars and quiz programme of PG students. Senior staff
members are invited for guest lectures in most of the conferences and workshops. In current year
two DA students appeared in exam. Both residents passed the examination.
Research: Research activities related to new drugs, techniques or equipment is done in
the department. Every year nearly 4 to 5 research subjects are studied and papers are presented
in various conferences.
Professional Contribution and Recognition: Dr. Bipin Patel, Professor and Head, has
been appointed as Member of Advisory Committee, Indian Journal of Anaesthesia. He has also
been appointed as Chairman of Indian Medical Association Standing Committee for national
planning of the health. He will be holding this post for three years. He has received ‘Best State
Secretary’ award by Indian Medical Association, head quarter. He has been also appointed as
President of Gujarat State Branch of Indian Society for the Study of Pain.
Dr. Geeta Joshi, Professor, has been elected as Hon. Secretary for ‘Indian Society for
Study of Pain’. She will be holding this post for 3 years.
Dr. Bhavna Shah, Associate Professor, is appointed as Treasurer for Indian Society for
Study of Pain. She was invited as a guest speaker in National Pain Conference. She is also
continued as Secretary and Treasurer for Gujarat State Branch of Indian Society of
th
Anaesthesiologist for 7 year. She is executive member of ISSP.
Dr. Dipika Patel, Associate Professor, is appointed as Treasurer for Gujarat State Branch
of Indian Society of Study of Pain.
Dr. Vinay Solanki, Resident Doctor, won the Second Prize among all residents doctors
for oral presentation of a case report in GISACON 2007.
Public Services: Dr. Geeta Joshi is working as a Core Team Member of Unnat
Gramsamaj Nirman Kendra, a NGO working for slum children. She is involved in various health
related activities in slums of Ahmedabad. A camp for plastic surgery is organised at Sewa Rural,
Jhagadia, Bharuch, every year. Department of anaesthesia provides their services at the camp.
Complementary Training Programme:
No. Programme Students
1 MD 3
(G) DEPARTMENT OF RADIOTHERAPY
Staff Pattern: There are three Professors, two Associate Professors, one Assistant
Professor and four Junior Lecturers, five Resident Doctors, six Physicists, sixteen Radiographers,
and two Mould Room Technicians.
Services: The department is fully equipped with four 6 MV Electa Linear Accelerators,
one Cobalt Machine, three Dimensional Conformal Radiation Therapy (3DCRT), Intensity
Modulated Radiotherapy (IMRT) Facility, Stereotactic Radiotherapy and Stereotactic
Radiosurgery Facility, one Contact Therapy Machine, one Low Dose Rate (LDR) Brachytherapy
Unit, three Micro Selectron High Dose Rate (HDR) Brachytherapy Units, two Electa Simulator
Machines, one Siemens CT Simulator Machine which is in radiology department.
22
Service Output:
No. Details of Work Done Number
1 OPD cases 15000
2 Cobalt Teletherapy 6500
3 Linear Accelerators 26000
4 Brachytherapy 3000
Activities: Clinical: The department is treating patients coming from nearby cities and
also from Rajasthan, Madhya Pradesh and Maharashtra. It also participates in GCRI academic
meetings.
Academic: Regular lectures, seminars twice weekly by resident doctors, and bed side
case presentation by resident doctors conducted in the department.
Research: Maintenance of patient’s record is done. The data is presented in national
level conferences and published in national journals.
Professional Contribution and Recognition: Dr. Rakesh Vyas, Professor and Head,
has been awarded citation for endowment oration at Tamilnadu during Conference of Association
of Medical Physicists of India in August 2007. He has been elected as President of Gujarat-MP-
Chhattisgadh Chapter of Association of Radiation Oncologists of India (AROI) during 5th West
Zone Chapter Conference of AROI, Padhar, Betul, in February 2008.
Dr. Maitrik Mehta, Resident, won Best Paper Award at 5th West Zone Chapter of AROI,
Padhar, Betul, during February 2008.
Dr. Pooja Nandwani Patel, Resident, won Travel Fellowship for Best Paper Award and
Dr. Neal Joseph Fellowship Award at Association of Radiation Oncologists of India Conference
held in Chennai during November 2007. She is recipient of Dr. TB Patel Gold Medal (Young
Scientist) for oral paper presentation during Hospital Day Celebration on April 19, 2008.
Workshop Organised: The department has organised Indo-American Collaborative
Workshop on November 17-18, 2007.
Complementary Training Programme:
No. Programme Students
1 MD 5
(H) OTHER SERVICES
These are ancillary services for patient care and play vital role in overall treatment of
patients. They are (H1) Nursing Services, (H2) Stoma Clinic, (H3) Prosthesis and Rehabilitation
Centre, (H4) Physiotherapy, (H5) Hospice Care and Home Hospice Service, (H6) Pharmacy and
(H7) Administrative Services.
(H1) Nursing Services
Staff Pattern: Its staff includes two Matrons (Grade - I), twenty five Head Nurses and of
them five are Nursing Supervisors, two hundred five Staff Nurses, six Junior Nursing Grade - A,
fifteen Junior Nursing Grade - B, and thirty one Nursing Assistants.
Services: We have diversified the services of nursing to various specialties like Stoma
Clinic and BMT unit rendering services to the patients as per the requirement and this is the new
development in the Nursing department. The future goals are to have trained oncology nurses in
maximum numbers and also to train the nurses for further sub-specialties. Also, to standardise
the nursing care that will help giving quality care to the patients. The senior and junior nursing
staff have attended national workshops related to their services.
(H2) Stoma Clinic
Staff Pattern: In stoma clinic two Enterostomal Therapist (CET qualified specialist) are
working. Services: This is the first Stoma Clinic in Gujarat State started on March 4, 1983. The
services offered by the department include: (1) Giving pre-operative counselling to the patients
23
and their relatives, (2) Stoma marking before operation to prevent future problem, (3) Selection of
the stoma bags according to stoma size and applying on o'stomy patient as well as faecal fistula
drainage patients, (4) Giving detailed instruction and advise about stoma bags and stoma
management to patients and their relatives and application of stoma bag, (5) Giving Post
operative counselling to patients and their relatives, (6) Keeping detailed record of Indoor and
Outdoor patients like Colostomy, Ileostomy, Ileal conduit faecal fistula and Drainage, (7) Keeping
detailed record of various types of stoma bags for indoor and outdoor patients, (8) Teaching
nursing students about colostomy care and, (9) Keeping the records of cancer care patients.
Service Output:
No. Details of Work Done New Cases Old Cases
1 Colostomy Patients 111 290
2 IIeostomy Patients 15 41
3 Ileal conduit + Urocolostomy patients 19 99
4 Drain + faecal fistula 25 7
5 Stoma bags record
Total number of bags given 5511
Total number of paid bags 5493
Total number bags given free 18
(H3) Prosthesis & Rehabilitation Centre
Staff Pattern: Department has one Assistant Medical Sculptor.
Services: The department prepares artificial limbs, organs, part of face and other
prosthesis. They are made from silicone and acrylic.
Service Output:
No. Details of Work Done Number No. Details of Work Done Number
1 Ear Prosthesis 8 6 Chin Prosthesis 1
2 Eye Prosthesis 33 7 Forehead Prosthesis 2
3 Nose Prosthesis 4 8 Thumb Prosthesis 2
4 Lip Prosthesis 2 9 Finger Prosthesis 29
5 Cheek Prosthesis 3 10 Breast Prosthesis 68
Activities: Clinical: The department is involved in making of artificial body parts for the
patients attending cancer institute. Not only cancer patients but patients handicapped from birth,
burns patients, patients of accidental injury and having lost body parts are also benefited from
this services.
Academic: Department arranges lectures for nursing students, also attend department
and get training in the prosthesis as it is one of the subjects of BSc and General Nursing
curriculum.
Public Services: Department takes special interest in preparation of Taylor's Brace for
spinal support.
(H4) Physiotherapy
Staff Pattern: There are one Senior Physiotherapist and two Junior Physiotherapists.
Service Output:
No. Details of Work Done Number
1. Physiotherapy to Indoor and Outdoor patients 18894
Activities: Clinical: The treatment mainly consist of pre and post operative chest
physiotherapy, pain relief and rehabilitation of hemiplegies, paraplegies, guadriplegies amputees
and any of the peripheral nerve injuries. Electrotherapy has various pain relieving modalities. The
department renders both indoor and outdoor services. Indoor services are mainly for post
24
operative phase for the patients who undergone surgery, those patients who are on ventilators
and ‘T’ stomy patients. These patients are given vigerous chest P.T. alongwith postural drainage
and nebulization. Neurosurgical patients are been given rehabilitature physiotherapy treatment.
The department also treats paediatric group of patients having the above problems, by
giving them quality of treatment which helps them to live near normal life. The patients of trismus
and radiation mucositis are being treated with the help of “scanner laser therapy machine” which
helps in reducing pain and healing of ulcers due to radiotherapy.
Academic: Nursing students attend the department and get training in physiotherapy as
it is one of the subjects of BSc/General Nursing Curriculum. The department gives clinical
teaching to students come from different physiotherapy colleagues. Postgraduate students are
doing dissertation under guidance of Dr. Manali Shah, Senior Physiotherapist.
Public Services: Our department sends many of the patients to prosthesis department
for spinal support and mouth opening devices for chronic Gutkha chewers which are provided to
the patients at very economical rate. The patients are then rehabilitated with various exercise
regimes.
(H5) Hospice Care and Home Hospice Service
At the COC, Vasna, terminally ill patients with cancer are given shelter, warmth and
palliative care. The patients are referred to us by Cancer Clinicians. Emergency services like
Ryle’s Tube insertion, Catheterisation, Pain relief, IV injection treatment etc. are being provided
on receiving request by relatives. A beautiful environment is provided and all efforts are made to
ease their suffering and make their life comfortable in the small huts with all facilities. Their
entertainment is specifically looked after.
Service Output:
No. Details of Work Done Number
1 Admissions 99
Public Services: Home Hospice services are offered to terminally ill cancer patients and
are attended at home.
(H6) Pharmacy
Staff Pattern: There is one Chief Pharmacist cum Store Officer, Eight Junior Pharmacists
and one Data Entry Operator.
Services: The system is now rearranged and all indoor as well as outdoors patients are
collecting their medicines from Main Pharmacy (room No. 76). The pharmacy computer linked
with all bill collection centres to know the day today availability stock of medicines in pharmacy.
Only for outdoor patients tablets/capsules are supplied from ground floor (room No. 25), which is
just near to cash collection counter. Indoor patients and Day Care patients (patient on
chemotherapy treatment) are now dispensed medicines from second floor (indoor pharmacy near
to BMT ward room No. 210). New cash collection centre for the indoor patients is started at room
No. 211. All department/ward medicines indents are supplied from second floor (room No. 209).
Administrative work of pharmacy (main store) along with all stocks of medicines and delivery of
purchased medicines are now accepted at second floor (room No. 209). Number of patients under
School Health Programme is markedly increased and for them all medicines are purchased and
supplied. Special services are provided to special room patients. Special services are also
provided to BMT patients and advance payment from various organisations and Central Govt.
employees are being collected. Also, payment is reimbursed for patients referred from various
organisations like Railway, IFFCO, ISRO, ONGC, Bank, CGHS, SGS, ECHS, BSNL, P&T, CM
Relief Fund, BSF, RBI etc. Patients under GCS adoption scheme and GCS Poor Patient Fund are
provided free pharmacy services as per rules of the institute.
(H7) Administrative Services
Staff Pattern: Hospital Administrator heads this service. There are two Class-I level, four
Class-II level and thirty-nine Class-III level employees. In addition three Resident Medical Officers
offer their services. An honorary Civil Engineer and a management trainee actively assist it.
25
For day-to-day smooth functioning of the various activities, hospital administration has 6
sections. (i) Human Resources Section, (ii) Secretarial Services Section, (iii) Store and Purchase
Section, (iv) Account Section, (v) Engineering & Maintenance Section, (vi) Resident Medical
Officer Section, and (vii) Public Relation Section.
(i) Human Resources Section
Activities: This section looks after the procedural aspects of the human resources
development, recruitment, promotion, disciplinary action etc. We have computerised system for
maintenance of presence of every employee and leave management of all the employees. The
section also maintains database of various training programmes and the trainees for our human
resources requirements as well as the section looks after the general administrative procedures.
(ii) Secretarial Services Section
Activities: Secretarial services are provided by this section with the help of ultramodern
equipments like computers, copiers, scanners, fax, Internet etc. The section also supports all the
secretarial requirements for the organisation of workshops, seminars, conferences, publications of
various materials etc.
(iii) Store and Purchase Section
Activities: The main duty of this section is to procure necessary consumables, purchase
of hospital supplies, medical and research equipments. It also looks after the maintenance
contracts, repairs of minor and major equipments etc.
(iv) Account Section
Activities: Account section looks after the maintenance of accounts, payments of various
bills, receiving hospital fees, payment of wages etc. All these activities are computerised and
most of the things are done with the help of computer.
(v) Engineering & Maintenance Section
Activities: Engineering & Maintenance section supports the hospital management by
undertaking various civil works, interior decoration, planning and execution of new purchases,
construction etc. Electrical engineer and his team looks after the day-to-day maintenance of
electrical installations, air-conditioning plants, Window Air Conditioners etc. They also provide
support for the maintenance of hospital's in-cable services and maintenance of sound systems in
the Cama Hall and for the various programmes arranged by the Institute. The hospital
management division also deputes employees from the aforesaid sections to attend various
programmes arranged by the AMA and other organisations to update their knowledge about the
current practices of their subjects.
(vi) Resident Medical Officer Section
Activities: The services offered by them include: (1) Supervision of and assistance to
clinical and supportive services of GCRI and COC, Vasna, (2) Guidance and help to patients
regarding treatment at GCRI, (3) Help to the needy patient to get their treatment at concessional
rate as per rules of the institute, (4) Supervises Patient Care and Home Hospice Services in
Ahmedabad and at COC, Vasna, (5) Conducting Patient Evaluation Meeting, and (6) Medical help
for the health of GCRI staff.
Professional Contribution and Recognition: Dr. Dhruti Desai, RMO, has attended
Hospital Management Programme from August 27-31, 2007 at Indian Institute of Management,
Ahmedabad.
(vii) Public Relation Section
Activities: The section looks after patient comfort level, makes a bridge between the
patient and doctor as per patient's need and report it to RMO for necessary actions.
26
III. CANCER RESEARCH & EDUCATION
Separate administrative arrangement in the form of Research and Education Services under
Dr. Shilin N. Shukla, Deputy Director (Research & Education) has helped the institute to
organise its research and educational activities and hence a definitive perspective and direction is
being provided in this aspect also. The principal areas include the (I) Research Wing (Cancer
Biology Department), (J) Educational Activities, (K) Library, and (L) Educational Graphics and
Medical Photography.
(I) RESEARCH WING (CANCER BIOLOGY DEPARTMENT)
(I1) Cell Biology Division
Staff Pattern: There are two Junior Scientific Officers, one Research Assistant, one
Junior Research Assistant, and six Research Fellows in ongoing tenured research projects.
Services: The Cell Biology Division has fine set up for clinical chromosome research and
diagnostic testing, mainly for leukemia patients of GCRI and referred cases for diagnosis and
prognosis. There are two automatic karyotyping and FISH imaging systems; IKAROS by
Metasystems, Germany, and Cytovision by Applied Imaging, USA, with two workstations each.
Hybridization and denaturation chamber (Thermobrite, Vysis, USA) helps in rapid and consistent
FISH assays. The facility for multiplex-FISH (from Gujarat State Biotechnology Mission project
grants) is first of its kind in the country. In addition to Karyotyping and FISH (Fluorescence in situ
hybridization), other cytogenetic endpoints namely; chromosome aberrations, sister chromatid
exchanges, centromeric band heterochromatin polymorphism are also employed.
Service Output:
No. Details of Work Done Number
1 Cytogenetic study of leukemia from bone marrow 1470
2 FISH tests for following genetic rearrangements
Translocation t(8;21) 5
Translocation t(9;22) 235
Translocation t(15;17) 45
Translocation t(12;21) 2
Translocation t(16;16)/inversion (16) 1
Rearrangements of 5q (two different loci) 1
Rearrangements of 7q (two different loci) 11
Copy number of X &/or Y 11
Rearrangements of MLL gene 3
Rearrangements/copy number determination in metaphase 7
for any of the whole chromosomes [1 to 22, X, & Y] -
3 Karyotyping in genetic cases 11
4 Multiplex-FISH 18
Activities: Clinical: Clinical cytogenetic services for leukemia patients include karyotypic
and FISH analysis in CML, APML, and various other leukemia to help diagnosis and prognosis.
Constitutional chromosome analysis by GTG banding and multiplex FISH is also carried out in
cases referred from all over Gujarat with indication of infertility and other genetic abnormalities.
Academic: Various graduate and post-graduate students from Ahmedabad, Vallabh
Vidhyanagar, Surendranagar, Rajkot, New Delhi, Hyderabad, Bangalore, Pune etc. visit the
department for observer ship, science projects, and dissertation. Personnel from various institutes
visit the department for technical training. Dr. Sonal Bakshi is a visiting lecturer for MSc
Biomedical Technology at Gujarat University. In a state-level seminar conducted by JJ Science
27
College, Microbiology Department, Nadiad, and at Gujarat State Biotechnology Mission, she
participated as a referee for the third year BSc students.
Research: The main research thrust of Cell Biology Division is chromosome analysis of
leukemia patients. Chromosomal anomalies are documented at diagnosis and during later stages
of the disease, which aids in prognostication and clinical research. Metaphase chromosomes are
obtained from the peripheral blood lymphocytes, bone marrow, and malignant effusions. The
novel chromosomal anomalies as per the leukemia subtype are contributed to existing pool of
databases of chromosomal aberrations in leukemia by publishing in national and international
journals. Karyotypic analysis by GTG banded metaphases is substantiated by locus specific &/or
whole chromosome FISH, and multiplex-FISH for increased sensitivity of chromosome anomaly
detection.
Complementary Training Programme:
No. Programme Students
1 PhD 2
2 Observership 151
3 Dissertation 1
4 Others 2
(I2) Molecular Endocrinology Division I
Staff Pattern: The division has one Senior Scientific Officer and two Junior Research
Fellows.
Services: Clinical evaluation of thyroid function tests and tumor markers are being
performed for diagnosis in patients with thyroid abnormalities and malignancies referred to the
division. Subsequent estimations of these hormones and tumor markers in serial samples are
also performed in follow-up studies in patients for further treatment modalities with request of
clinical practitioners. Research projects financially supported by various agencies are also carried
out. Also, gives training to under graduate and post graduate students coming from various
colleges, faculties and universities as well as guiding post graduate students for their dissertation
as a partial fulfillment of the requirement by the university for their Master’s Degree.
Service Output:
No. Details of Work Done Number
1 Total T3 3139
2 Total T4 3139
3 TSH 3139
4 Free T4 543
5 Free T3 310
6 Thyroglobulin 103
7 TPO-Ab 88
8 CEA 93
9 CA 19-9 190
10 CA 72-4 190
11 p27 80
12 EMA 98
13 Thyroglobulin 98
28
Activities: Clinical: The division is mainly engaged for clinical diagnostic and cancer
related research work. As far as the diagnostic work is concerned, patients are being referred
from institutional departments like Endocrinology/ Surgical Oncology/ Radiotherapy/ health check-
up programme of Community Oncology Centre, Vasna/ OPD of Civil Hospital, Ahmedabad, as
well as by other private Clinicians of Gujarat and even allied states, were evaluated for thyroid
function tests.
Much of the patients referred for thyroid function tests for thyroid abnormalities had
common symptoms of thyroid swelling. In our patients, more than 65% had complaint of thyroid
swelling irrespective of Hypo-/Hyperthyroidism. Amongst referrals, incidence of thyroid
abnormality was evident in 50% and more frequent in females as compared to males. Ratio of
hypothyroidism was around two fold higher than hyperthyroidism in abnormal patients. Chances
of malignancies were noticed more with increase in duration of Goiter in our patient’s history.
Subnormal or above normal T3, T4 with normal or upper borderline TSH levels was a common
feature in our pre-treated thyroid malignant group. Incidence of thyroid malignancy was more
pronounced in solitary nodules as compared to multinodular goiter in our study groups. It is also
advisable that asymptomatic goiter cannot be ignored for presence of malignancy. If thyroid
swelling is noticed one has to refer to the clinician without delay for further management of the
goiter.
Academic: Various students from several institutions/universities are given training
during their vacation period.
Research: Research projects financially supported by Gujarat Cancer Society and DMER
are on-going.
Professional Contribution and Recognition: Dr. Girish Patel, Senior Scientific Officer,
has been enrolled as PhD Guiding Teacher in Life Science by Gujarat University, Ahmedabad.
Complementary Training Programme:
No. Programme Students
1 Observership 158
2 Dissertation (completed) 2
3 Dissertation (on-going) 1
Molecular Endocrinology Division II
Staff Pattern: There are two Senior Scientific Officers, one Research Assistant, two
Junior Research Assistants and one Junior Research Fellow.
Services: The Division is fully equipped with Packard Gamma Counter, Beta Counter,
Thermal Cycler, Ultracentrifuge and Spectrophotometer.
Service Output:
No. Details of Work Done Number
1 Clinical Work 8123
B-Human Chorionic Gonadotropin (B-HCG) 1111
Alpha Fetoprotein (AFP) 1236
Carcinoembryonic Antigen (CEA) 1988
Prostate Specific Antigen (PSA) 977
CA-125 1744
CA 19-9 125
CA 15-3 01
Parathyroid Hormone (PTH) 41
Cortisol 98
29
No. Details of Work Done Number
Follicle Stimulating Hormone (FSH) 161
Leutinizing Hormone (LH) 141
Prolactin (PRL) 200
Testosterone (T) 60
Estradiol (E2) 73
Growth Hormone (GH) 167
2 Research Work
Immunohistochemistry 159
Stat1 35
Stat3 23
Stat5 101
DNA extraction from blood/ tissues 61
RT-PCR 140
Stat1 70
Stat3 70
Activities: Clinical: Includes quantitative evaluation of tumor markers and endocrine
hormonal profile markers.
Academic: Imparting research training to undergraduate and postgraduate students.
Under the GSBTM Multi-institutional Training Programme in Molecular Biology and Bioinformatics
for Teachers and Researchers of Gujarat, May 17-25, 2007, Dr. Neelam Shah presented PCR
and Blotting Techniques.
Research: Early detection depends on a better understanding of the molecular
mechanisms that drives tumor initiation and progression. For this, it is necessary to define genetic
instability and the genetic events involved in signal transduction, transcription factors and cell
cycle regulatory pathways. Based on this, our division is actively involved in studying the clinical
relevance of multiple genetic alterations in malignancies of breast, colon/rectum and oral cavity.
The other focus of research involves detection of micrometastasis using tumor associated genes.
Professional Contribution and Recognition: As part of the Dr. TB Patel Centenary
Year and Research Wing Silver Jubilee Celebrations, the division compiled the Research
Publications of the Research Wing from 1984 to 2007 which were presented as Archives of
Publications (Volume I-III).
Ms. Trupti Trivedi, Research Assistant, awarded PhD degree by Gujarat University for
thesis entitled 'A study of molecular markers in patients with pre-malignant and malignant lesions
of the oral cavity' in May 2007.
Ms. Bindu Yagnik, Junior Research Fellow, won the third prize for the poster on
'Nanotechnology: A basis for next revolution in cancer' at Poster Presentation Competition on
October 3, 2007.
Ms. Toral Kobawala, Junior Research Assistant, won the first prize in two different
events. Best Essay Award for essay entitled 'Modern techniques in drug delivery' and Rajnikant
Baxi Award for the best poster presentation on 'Molecular alterations in oral carcinogenesis:
th
Significant risk predictors in malignant transformation and tumor progression' at 27 IACR,
February 7-9, 2008.
Poster Presentation Competition Organised: The division organised the Poster
Presentation Competition Event on October 3, 2007, at GCRI as a part of Dr. TB Patel Centenary
Year and Research Wing Silver Jubilee Celebrations.
30
Complementary Training Programme:
No. Programme Students
1 PhD 1
2 Observership 158
3 Dissertation 2
(I3) Receptor & Growth Factor Laboratory
Staff Pattern: The staff includes one Senior Scientific Officer, one Research Assistant,
two Junior Research Assistants and two Junior Research Fellows.
Services: The department is largely connected to the research and education services.
We have started the services for the estimation of IGF axis molecules in the referrals from
Radiotherapy and Endocrine OPD.
Service Output:
No. Details of Work Done Number
1 Enzyme Immunoassays/ In-House ELISA 700
(Matrix Metalloproteinases and their activities; Transforming Growth
Factor Beta axis related molecules, PF-4)
2 Radioimmunoassay/ Immunoradiometric assays 500
(Insulin like Growth Factor axis molecules)
3 Radio-receptor Assays 100
Estrogen Receptors, Progesterone Receptors, Retinoic acid receptors
4 Real Time PCR 200
5 Immunoprecipitation - ER, PR isoforms 50
Activities: Academic: The members of the laboratory regularly participate in the weekly
departmental seminars as well as a regular biweekly intra-lab seminar is also actively organised.
The laboratory also undertakes the training to the observers (post-graduate students attending
the institute from several universities) and to the dissertations students.
Research: Receptor & Growth Factor Laboratory work on signal transduction pathways
and their implication in etiology, diagnosis, prognosis and treatment monitoring of different tumor
types. The work is directed towards establishment of a battery of tumor markers (proved and not
proved) for the aforesaid aim in solid tumors like breast tumors, brain tumors (Meningioma,
Glioma) and uterine cervix. The aim to decipher the mechanisms / pathways / molecules
connected to cross talk between hormone receptors and growth factors in set of patients in
Western India. Also look towards prediction of radio-sensitivity of cervical tumors, and estimation
of hormone receptors like Estrogen Receptor and their variants, Progesterone Receptor and their
isoforms (PR-A & B), Retinoid Acid Receptors (RAR, RXR), Growth factor axes like Insulin like
Growth Factor axis (IGF -1, -2; Free IGF-1, IGFBPs -2, -3), Vascular Endothelial Growth Factor,
Hepatocyte Growth Factor and Matrix Metalloproteinases (MMP -2, -9) and their activities. All
these markers are quantitated at protein levels with RIA, ELISA, and IRMA. Quantitative as well
qualitative estimation of Transforming Growth Factor betas (TGF β-1, -2) and signaling molecules
at both proteins as well RNA level (with real time PCR) is being done. This work has been carried
out with the help of seven ongoing projects funded by agencies like GCS, DMER and GSBTM.
Professional Contribution and Recognition: Dr. Sunil Trivedi, Senior Scientific
Officer, acted as visiting Faculty for post graduate programme in Biomedical Technology and in
Human Genetics, Gujarat University. He is Guest Speaker at SP University and Nirma University,
and an examiner of MPharm (Biotechnology), Ganpat University, Kherva. He was to National
Institute of Occupational Health (NIOH) as a member on their purchase committee and as a
member on their staff selection committee. He worked as Technically Qualified Expert for scrutiny
and purchase of instruments and chemicals at the institute.
31
Ms. Apexa Raval, Junior Research Assistant, received best poster presentation prize on
‘Nanotechnology: Basis for next revolution in cancer’ at Poster Presentation Competition on
October 3, 2007.
Mr. Pankil Bhatt, Junior Research Fellow, received best poster presentation prize on
'Stem Cells: A cure to cancer?' at Poster Presentation Competition on October 3, 2007.
Conference Organised: Dr. Sunil Trivedi was a joint organiser of a workshop on ‘Real
Time PCR’ in collaboration with Foundation for Research in Genetics and Endocrinology (FRIGE),
November 27, 2007. He and the lab members organised the pre-conference event CCRE
(Continuing Cancer Research Education) on February 6, 2008, and 27th Annual Convention of
Indian Association for Cancer Research at our institute during February 7-9, 2008.
Complementary Training Programme:
No. Programme Students
1 PhD 1
2 Observership 158
3 Dissertation 7
(I4) Biochemistry Research Division
Staff Pattern: There are one Senior Scientific Officer, two Research Assistants, and two
Junior Research Fellows.
Service Output:
No. Details of Work Done Number
1 Serum LDH 1812
2 Serum Protein Electrophoresis 176
3 Serum Iron 47
4 Serum TIBC 43
Activities: Academic: Theoretical and practical demonstration of various molecular
biology and biochemical techniques were carried out for the students who came as observers
from various universities as well as for MLT students.
Research: The area of our research curiosity integrated following aspects: (1)
assessment of the role of tobacco habits, various other lifestyle and sociodemographic factors,
dietary patterns and interplay of enzymatic and non-enzymatic antioxidants in aetiology of
tobacco related cancers, (2) Applications of proteomics in cancer research by analysis of 2D
maps from serum and cytosolic proteins of patients with various malignancies, (3) The alterations
in glycoproteins, membrane glycolipids, glycoprotein metabolic enzymes and glycoprotein
electrophoretic changes to assess their role in diagnosis, prognostication and management of
cancer patients, (4) NF-kB activation pathway and apoptosis in cancer, (5) The role of telomeres,
telomerase and its components, and matrix metalloproteinases and tissue inhibitor of
metalloproteinases in various malignancies to assess their clinical usefulness. The changes in all
bio-molecular parameters would be helpful for prognostication, treatment monitoring and in early
prediction of relapse in cancer patients. We have eight ongoing research projects based on the
above notion. The data obtained from these studies is presented in national/international level
conferences and also published in national/international journals. A weekly seminar is also
conducted in the division by staff members to discuss recent trends in cancer research.
Professional Contribution and Recognition: The division received Smt. Vibha Mehta
Rotating Trophy for maximum research paper publications during the year 2007-2008.
Dr. Prabhudas Patel, Senior Scientific Officer, was editor for Indian Association for
Cancer Research (IACR) News Letter and released two issues of the News Letter. He delivered
three guest lectures at national conferences during the year.
32
Dr. Franky Shah, Research Assistant, received first prize for poster presentation at 2nd
International Symposium on Translational Cancer Research held at Lonavala during December 9-
12, 2007.
Ms. Vandana Patel, Junior Research Fellow, received best poster award for poster
presentation on 'Nanotechnology: Basis for next revolution in cancer' in poster competition on
October 3, 2007; young investigators award for poster presentation at 34th Annual Conference of
Association of Clinical Biochemists of India, New Delhi, during December 17-20, 2007, and
second prize for poster presentation in National Conference on Apoptosis and Cancer held at MS
University, Vadodara, during December 28–29, 2007.
Ms. Hetvi Patel, Junior Research Fellow, received third prize in poster competition at
symposium on 'Natural compounds in the management of cancer' on December 3, 2007, and
second prize in oral competition at seminar on ‘Human Health Care: Redefined – 2008’ at School
of Sciences, Gujarat University, Ahmedabad, on March 17, 2008. She is recipient of Dr. TB Patel
Silver Medal (Young Scientist) for oral paper presentation during Hospital Day Celebration on
April 19, 2008.
Complementary Training Programme:
No. Programme Students
1 PhD 2
2 Observership 158
3 Dissertation 5
(I5) Immunohistochemistry Division
Staff Pattern: The staff include one Senior Scientific Officer, one Research Assistant, two
Junior Research Assistants, and two Junior Research Fellows.
Services: The division works in coordination with pathology department. The division is
well-equipped for immunohistochemistry and flowcytometry work. Immunohistochemistry and
flowcytometry have been carried out to aid histopathological and haematological diagnosis.
Service Output:
No. Details of Work Done Number Patients
1 Estrogen and Progesterone receptors (ER/PR) 1762 881
2 Her-2 neu 223 223
3 Immunophenotyping markers by Flowcytometry 5124 267
4 Immunohistochemical Markers 9133 1684
Activities: Clinical: At the division, 54 different immunohistochemical markers are being
routinely done. Further, immunophenotyping of acute leukaemia and CLPDs is done using
flowcytometer.
Academic: The division participates in the academic activities of the institute by
enrolment of PhD students, MSc/MPharm Dissertation students and Summer Training
Programme for MSc/BSc students. Dr. Hemangini Vora gave a lecture on 'Flowcytometry: A
versatile tool' in GSBTM multi-institutional training programme in Molecular Biology and
Bioinformatics for Teachers and Researchers of Gujarat conducted at GCRI during May 17-25,
2007.
Research: The main areas of research include studies of HER-2 neu signalling and
epithelial-mesenchymal transition in breast cancer. Also, role of FLT3 and PRR in AML, and MRD
detection in AML and ALL are being studied. In collaboration with Surgical Department, (1)
molecular analysis of histopathologically negative surgical margins of head and neck cancer
patients is carried out to identify high risk patients for loco-regional recurrences, and (2)
identification of predictors of response to neoadjuvant chemotherapy in locally advanced head
and neck cancer patients is being studied.
33
Based on above research areas nine projects are ongoing in the division.
Professional Contribution and Recognition: As part of Dr. TB Patel Centenary Year
and Research Wing Silver Jubilee Celebrations, Archival Vistas – assembled petals of Research
Projects, Publications and Presentations of the Research Wing from 1984 to 2007 was complied
by the division.
Ms. Shalvi Mehta, Junior Research Assistant, won first prize for oral presentation in 32nd
Annual Conference of Gujarat Pathologists & Microbiologists, Vadodara, on February 3, 2008.
Ms. Birva Brahmbhatt, Junior Research Fellow, won fourth prize in National Symposium
on Apoptosis and Cancer at MS University, Vadodara, during December 28-29, 2007.
Seminar Organised: As a part of Dr. TB Patel Centenary Year and Research Wing Silver
Jubilee Celebrations, 'Seminar on Current Trends in Molecular Biology and Clinical Drug Trials'
was organised by Dr. Hemangini Vora and her team on October 3, 2007. In this seminar 450
students from various universities of Gujarat State participated.
Complementary Training Programme:
No. Programme Students
1 PhD 3
2 Observership 200
3 Dissertation (completed) 6
4 Dissertation (on-going) 5
(I6) Medicinal Chemistry & Pharmacogenomics
Staff Pattern: The staffs include one Junior Scientific Officer and one Junior Research
Fellow.
Services: The division is equipped with computer and scanner for bioinformatics work.
Service Output: NABL accreditation documentation and co-ordination.
No. Details of Work Done Number
1 IL-1, IL-3, IL-5, IL-6, G-CSF, TNFalpha, TGF 48
beta, EPO
2 Cow Urine fractionation, protein, 16
electrophoresis
3 Natural Compound Scaffold Design – 15
Docking studies, MLL, Hsp70, LDH, Bcr-abl
4 Data Mining – Journal Back Volume 60
Downloading
5 e-books 346
Professional Contribution and Recognition: Dr. Rakesh Rawal, Junior Scientific
Officer, elected as Judge in Bioinformatics for Science Excellence 2008 (SCIXL-2008) event held
at Gujarat University on January 5, 2008.
Seminar Organised: Symposium on 'Natural compounds in the management of cancer'
was organised by Dr. Rakesh Rawal on December 3, 2007
Complementary Training Programme:
No. Programme Students
1 Dissertation 1
34
(I7) Joint Activities of Research Wing (Cancer Biology)
Educational Meeting: The staff members of the Research Divisions conduct a weekly
presentation on friday and discuss topics related to basic and clinical cancer research and its
utility to Cancer Clinics. Total forty-two presentations were made in this year. Dr. Prabhudas
Patel, Senior Scientific Officer, is the coordinator of this meeting.
Silver Jubilee Celebration of GCRI Research Wing
As a part of Silver Jubilee Celebrations of Department of Cancer Biology (Research
Wing), the department has organised 8 academic events. The Research Wing is carrying out
clinical and applied research activities on all possible biomedical resources available at GCRI. Its
function may be described aptly in the following words of wisdom which may now onwards
become its motto also.
On this occasion, series of books (i) Archives of Publications (Volume I-III), compiled by
Dr. Neelam Shah, and (ii) Archival Vistas (projects/publications/presentations compiled by
Dr. Hemangini Vora, awards/honours/achievements compiled by Dr. Prabhudas Patel and
Dr. Sonal Bakshi were released. They represent most of the work and contribution of the
scientists of the institute. It also gives self-confidence that in the coming years we shall be able to
meet the challenges and expectations that future has stored in its hidden basket.
May 17-25, 2007 - 2nd launch Multi-institutional Training Programme in Molecular Biology
and Bioinformatics for Teachers and Researchers of Gujarat: This training programme was
organised by GSBTM on May 17-25, 2007. This programme was carried out at Biochemistry
Research Division and co-ordinator was Dr. Prabhudas Patel. GCRI was a network partner for
the programme along with Forensic Science Laboratory, Gandhinagar, and Anand Agriculture
University, Anand. The programme aimed at human resource development to ensure that the
teachers and researchers of Gujarat have the capacity and capability to carry out the activities
assigned to them. The faculty members were from various research departments of GCRI. A total
of 32 trainees from various institutes and colleges of Gujarat participated in the programme and
learnt various techniques in molecular biology.
July 9, 2007 - Symposium on Lysosomal Storage Disorders: Helping Patients with Rare
Genetic Diseases: GCRI was chosen by the Government of Gujarat to host a symposium on
'Lysosomal storage disorders: Helping patients with rare genetic diseases'. The one day event
was jointly organised with Genzyme CEE, GmbH; a company with major contribution in LSD
patient care with local support from the Biocare Research (I) Pvt. Ltd.
October 3, 2007 - Current Trends in Molecular Biology and Clinical Drug Trials: This
seminar was hosted under the patronage of GCRI, GCS, GSBTM and Indian Association for
Cancer Research-Gujarat Chapter on October 3, 2007. The programme was mainly for the post-
graduate students of science and pharmacy faculties. In the seminar, 425 students participated
from 25 different institutions/colleges of Gujarat. The students were postgraduates of science and
pharmacy faculties. Also, 20 renowned faculties from 15 institutions shared their knowledge with
bright students of Gujarat. This was organised by Immunohistochemistry Division and Dr.
Hemangini Vora was the Organising Secretary.
October 3, 2007 - Poster Competition on Nanotechnology: 1) Basis for next revolution in
cancer and 2) Stem cells: A cure to cancer?: A poster presentation competition coordinated by
Dr. Neelam Shah, Division of Molecular Endocrinology II, was organised on October 3, 2007, in
company with a seminar on ‘Current Trends in Molecular Biology and Clinical Drug Trials’, the
main event of the day. The total student participation was 69 and the posters displayed were 45,
which included 26 on Stem Cells: A cure to cancer?, and 19 on Nanotechnology: Basis for next
revolution in cancer.
35
November 27, 2007 - One Day Workshop on ‘Real Time PCR’ in Collaboration with
Foundation for Research in Genetics and Endocrinology (FRIGE): The workshop was
conceived as a part of training programme which FRIGE has launched for training of the 20
faculty from various places in the country in molecular genetics. Since our institute has a facility
for Real Time PCR in RGFL Lab they sought a help of the institute which was accepted by the
Director, GCRI, and conducted by Dr. Sunil Trivedi.
December 3, 2007 - Natural Compounds in Management of Cancer: A symposium on ‘Natural
compounds in the management of cancer’ was organised by GCRI, GCS and Indian Association
for Cancer Research (Gujarat Chapter) on December 3, 2007, with a generous support from
GUJCOST. There were 250 participants including medical oncologists, research scholars,
masters degree students (pharmacy, biotechnology, biochemistry), MD (Ayur & Homeopath). All
the delegates appreciated the symposium and interacted with the speakers. The symposium also
included a poster competition for students on ‘Herbal medicine in cancer management’.
Dr. Rakesh Rawal was the Organising Secretary of this symposium.
December 18-31, 2007 - GenDioT, Training Programme for Genetic Diagnostics: Cell Biology
Division was one of the three resource laboratories of Ahmedabad for the GenDioT. The genetic
diagnosis training was planned for 15 participants including basic research students, post
graduate and medical teachers, and clinicians from different parts of Gujarat. During December
18-31, 2007, two batches of participants for one week attended the laboratory for hands-on
training.
February 6–9, 2008 - 27th Annual Convention of Indian Association for Cancer Research -
Networking Research to Applications & International Symposium on Frontiers in
Functional Genomics: GCRI and GCS had organised the 27th Annual Convention of Indian
Association for Cancer Research & International Symposium on ‘Frontiers in Functional
Genomics’ on February 6-9, 2008. The pre-conference event ‘Continuing Cancer Research
Education’ (CCRE) was designed especially for the benefit of PhD students. A total of 200
participants from all over India participated in the convention. The masters of different areas in
cancer research from India as well as from around the globe were the resource faculty for
IACRCON-2008. Twenty-three eminent international speakers from USA, Switzerland, Finland,
Germany, Belgium, Austria and Netherlands working in various super-specialties of cancer
research were invited to share their knowledge. Twenty national resource faculties shared their
experiences along with them. Dr. Sunil Trivedi was the organising secretary of the event.
(J) EDUCATIONAL ACTIVITIES
The Institute is engaged in various types of educational and training programmes, like
(J1) Formal Educational Courses, (J2) Complementary Training Programme to Formal Education,
(J3) Professional Training to Doctors and Scientists (Conferences, Workshops), (J4) Professional
Training to Paramedics (Technological Courses), (J5) Community Education and Awareness
Programmes, (J6) Cancer Information Centre, (J7) Staff Training – Intramural and Extramural,
(J8) Hospital Day Celebration - Research and Educational Aspects, (J9) Clinical Meetings, (J10)
Activities of the Scientific Research Committee, and (J11) GCS Research Bulletin.
(J1) Formal Educational Courses
The Institute is affiliated to the B.J. Medical College and Gujarat University, Ahmedabad,
for subspeciality teaching in the subjects of Medical and Surgical Oncology (DM and MCh
courses) as well as postgraduate teaching in subjects like Pathology, Radiodiagnosis,
Gynaecological Oncology, Anaesthesiology and Radiotherapy (MD, DCP, DMRE, DA courses).
The Institute is also recognised for PhD degree from Gujarat University (Life Sciences and
Medical Microbiology) and MS University (Biochemistry). Hence, there are over 82 recognised
teachers and over 69 students. Details of the Formal Educational Courses during 2007-2008 are
as follows:
36
Department /Division Course Students Title of the Dissertation/Thesis
Radiodiagnosis DMRE 4 -
Pathology MD 7 1. Retrospective study of soft tissue sarcoma
2. Pattern of invasion in oral tongue cancer
as a prognostic parameter
3. Retrospective study of stereotactic brain
biopsy
4. Histopathological and FNAC correlation of
lung mass
5. Pathological prognostic parameters of soft
tissue sarcoma
6. ER and PR receptors in breast cancer
7. Study of GIST
Microbiology MD 1 1. The study of prevalence of Methicilin
resistance staphylococcus aureus (MRSA)
with particular mention of low level
Vancomycin resistance in infected patients
and constant surveillance, control and
treatment measures
Medical PhD 1 1. Detection of high risk human papilloma
Microbiology virus in cancerous and non-cancerous
cervical lesions by polymerase chain
reaction
Radiodiagnosis MD 8 1. Role of CT in large bowel pathologies
2. Role of mammography and intervention in
non-palpable breast lesion
3. Imaging in characterisation and staging of
pancreatic malignancy
4. Role of CT scan in diagnosis and staging
of cancer of the larynx
5. Role of MRI in brain tumor
6. Role of MRI in bone tumor
7. MRI evaluation of maxillary mass
8. Role of MRI in staging of cancer of the
cervix
Surgical Oncology MCh 12 1. Sentinel node biopsy in carcinoma of
penis
2. Tumour thickness in tongue in relation
with neck node metastasis
37
Department /Division Course Students Title of the Dissertation/Thesis
Surgical Oncology MCh 3. Near total laryngectomy in laryngeal and
pyriform fossa cancers
4. Methylene blue dye for validation study of
sentinel node in carcinoma of breast
5. Clinical study of malignant salivary gland
tumour
6. Prospective study of neoadjuvant CT in
locally advanced buccal mucosa cancers
7. Comparative study of open vs minimal
invasive surgery for carcinoma of
oesophagus
8. Treatment outcome in tumor of
hypopharynx except post cricoid
concurrent chemoradiation vs total
laryngectomy
9. A study of management extremity for soft
tissue sarcoma
10. Study of conventional vs total laparoscopic
stomach pull up in TPLO for post cricoid
cancers
11. Impact of neoadjuvant CT in locally
advanced operable buccal mucosa
cancers
12. Study to compare the results of cases of
oesophageal cancer treated by transhiatal
vs total three stage oesophagectomy
(THE vs TTE)
Gynaecological Oncology MD 8 1. Pre-operative and histo-pathological
evaluation in mangement of adnexal
masses
2. RMI in management of ovarian cancer
3. Our experience with carcinoma of
endometrium
4. Clinical profile of patients with ovarian
mass
5. Managenent of gestational trophoblastic
disease
6. Intraoperative management of pelvic mass
based on frozen section and final clinical
outcome
7. Role of VILI in detection of precancerous
lesion of cervix at community level and at
GCRI
8. Urological complications in oncogynaec
38
Department /Division Course Students Title of the Dissertation/Thesis
Medical Oncology DM 12 1. Carcinoma of nasopharynx: Role of CT-RT
versus RT in locally advanced carcinoma
of nasopharynx
2. Clinical profile and induction outcome of
paediatric B cell NHL
3. PAIF chemotherapy in unresectable
hepatocellular carcinoma
4. Impact of growth factors in induction
treatment of acute leukemias
5. Study of MVP vs Carboplatin Gemcitabine
in advanced carcinoma stage NSCLC
6. Study comparing melphalan, thalidomide
and prednisolone versus melphalan,
prednisolone in newly diagnosed patients
of multiple myeloma
7. Neoadjuvant chemotherapy in locally
advanced carcinoma of esophagus
8. A clinical profile of GIST with special
reference to imatinib
9. Randomised study comparing sequential
therapy with or without gefitinib in patients
with locally advanced oral cavity cancers
10. Clinical profile of non small cell carcinoma
lung in nonsmokers
11. Clinical profile of patients with imatinib
resistance in CML-CP
12. Clinical profile, cytogenetics and induction
outcome in paediatric AML with BFM 93
protocol
Anaesthesiology MD 3 1. Study of effect of succinylcholine and
rocuronium during intubating and
laryngoscopy
2. Comparative study of effect of pre-
emptive analgesia with epidural
buprenorphine alone in lower limb
amputation
3. Study of ondansetron, dexamethasone
and propofol in prevention of nausea and
vomiting following thyroidectomy
Radiotherapy MD 5 1. Comparison of concurrent chemotherapy
using carboplatin and radiotherapy in
patients with locally advanced
oropharyngeal cancers
2. Comparison of concurrent chemoradiation
using paclitaxel versus radiotherapy alone
in locally advanced Head and Neck
cancers
3. IMRT in Head and Neck Cancer
4. Effect of chemoradiation on the levels of
IGF-1 and IGF-2 in patients of carcinoma
cervix stage III B
39
Department /Division Course Students Title of the Dissertation/Thesis
Radiotherapy MD 5. Comparison of concomitant boost
accelerated fractionation versus
concurrent chemoradiation with weekly
docetaxel in locally advanced head and
neck cancers
Cell Biology PhD 2 1. Role of cytogenetic studies in AML
2. Role of cytogenetic studies in ALL
Receptor and Growth PhD 1 1. Study of transforming growth factor beta
Factor Lab axis in breast carcinoma
Biochemistry Research PhD 2 1. Significance of protein changes in cancer
2. Insight into molecular mechanism of oral
cancer
Immunohistochemistry PhD 3 1. Significance of molecular markers in
breast carcinoma
2. Genetic and epigenetic changes in benign
and malignant breast diseases
3. Evaluation of molecular markers in acute
myeloid leukemia
Total Theses and Dissertations = 69 (PG Courses: 36; Speciality (DM, MCh): 24; PhD: 9)
(J2) Complementary Training Programme to Formal Education
GCRI allows its infrastructural facilities and educative talent to be used by other educational
institutions to give professional training to their students, who come for observership, fellowship,
project work, dissertation work, PhD work, apprenticeship, etc. Total 953 students from 101
institutions had taken benefit of learning and training facility and opportunity provided by us.
Observers:
No. Institution Observers GCRI Department Duration
Medical Institutions
1 Arogya Hospital, Indore 1 Gynaecological 31 Days
Oncology
2 BJ Medical College, Ahmedabad 1 Blood Bank 30 Days
3 2 Gynaecological 90 Days
Oncology
4 15 Medical Oncology 30 Days
5 4 105 Days
6 8 Pathology 30 Days
7 13 Surgical Oncology 30 Days
8 12 Gynaecological 90 Days
Oncology
9 City Hospital, Rajkot 1 Pathology 30 Days
10 Civil Hospital, Ahmedabad 2 Blood Bank 15 Days
11 Darsh Gastroenterology & Surgical 1 IVTC 10 Days
Hospital, Ahmedabad
40
No. Institution Observers GCRI Department Duration
12 Dietetic Department, Civil Hospital, 1 RMO Office 13 Days
Ahmedabad
13 Dr. Pallavi Dixit, Ahmedabad 1 Neurosurgery 25 Days
Anaesthesiology
14 Dr. Pankaj Mahesh, Technologist, 1 Radiotherapy 120 Days
Raipur, Chhatisgarh
15 Dr. Ripal Sharma, Ahmedabad 1 Physiotherapy 30 Days
16 Dr. Bhupendra Sharma, SP Medical 1 Urosurgery 180 Days
College, Bikaner, Rajasthan Surgical Oncology
17 Dr. Devdutt Dabholkar, Bombay 1 Gynecological 30 Days
Oncology
18 Dr. Kanjani Shukla, MN, USA 1 Gynecological 24 Days
Oncology
Surgical Oncology
19 Dr. MI Laxmidhar, COC, Vasna 1 Surgical Oncology 3 Days per
week
20 Dr. Naveen Singh, Ghaziabad 1 30 Days
21 Dr. Saumin Shah 1 30 Days
22 Dr. Shailesh Patel, Ahmedabad 1 90 Days
23 Gautam Hospital, Deesa 1 Urology 31 Days
24 Ghevariya Hospital, Bhavnagar 1 Pathology 30 Days
25 Govt. Dental College & Hospital, 98 Surgical Oncology 3 - 10 Days
26 Ahmedabad 4 12 - 16
Days
27 4 Pathology 14 - 31
Research Divisions Days
28 2 Surgical Oncology 30 Days
29 HM Patel Centre for Medical Care & 3 Surgical Oncology 30 Days
30 Education, (Pramukhswami Medical 1 Gynaecological 30 Days
College), Karamsad Oncology
31 KM Shah Dental College & Hospital, 3 Pathology 93 Days
Piparia, Baroda Research Divisions
32 Kakatiya Medical Co, Warangal, AP 1 Radiodiagnosis 90 Days
33 MP Shah Medical College, Jamnagar 8 Radiodiagnosis 15 Days
Nuclear Medicine
34 Medical College, Bhavnagar 1 Surgical Oncology 25 Days
35 1 Medical Oncology 30 Days
36 Medical College, Vadodara 21 Radiodiagnosis 15 Days
37 Mr. Ameya Boprikar, McMaster 1 Musculoskeletal 40 Days
University, Canada Surgery
38 MS General Surgery, Gollala 2 Surgical Oncology 30 Days
Mammidada, East Godavari, AP
39 Muni. Institute of Medical & Research, 2
Surat
41
No. Institution Observers GCRI Department Duration
40 Nahrain University, Medical College, 1 Gynaecological 60 Days
Iraq, Baghdad Oncology
41 Pacific Detnal College & Hospital, 4 Surgical Oncology 28 Days
Udaipur Pathology
42 Prathma Blood Centre, Ahmedabad 3 Anaesthesiology 3 - 12 Days
Pathology
43 Rajkot Cancer Society, Rajkot 1 Gynaecological 1 Day
Oncology
44 Sardar Smarak Hospital, Bardoli 1 IVTC 15 Days
45 Trimurthy Hospital, Bavla 1 18 Days
46 VS Hospital, Ahmedabad 3 16 - 22
Days
Colleges
47 Ahmedabad Academy of Paramedical 81 Physiotherapy 5 Days
Sciences, Ahmedabad
48 Amity University, Noida 6 Research Divisions 28 Days
49 Bharati Vidyapeeth University, Rajiv 1 15 Days
Gandhi Institute of IT & BT, Pune
50 Biochemistry Dept., School of Sciences, 5 20 Days
Gujarat University, Ahmedabad
51 Biomedical Technology Dept., School of 37 Research Divisions 27 Days
Sciences, Gujarat University, Pathology
Ahmedabad
52 Biotechnology Dept., School of 2 Research Divisions 15 - 26
Sciences, Gujarat University, Days
Ahmedabad
53 BRD School of Biosciences, Sardar 3 28 - 35
Patel University, Vallabh Vidyanagar Days
54 BV Patel Pharmaceutical Education & 1 2 Days
Research Development (PERD) Centre,
Ahmedabad
55 Community Medicine Department, BJ 25 COC, Vasna 10 Days
Medical College, Ahmedabad
56 Computer Science Dept., Veer Narmad 4 Research Divisions 4 Days
South Gujarat University, Surat
57 CU Shah College of Engineering & 15 Research Divisions 30 Days
Technology, Wadhwan Nuclear Medicine
Radiodiagnosis
Radiotherapy
Physiotherapy
Operation Theatre
58 Dept. of Chemistry, Saurashtra 2 Research Divisions 13 - 14
University, Rajkot Days
59 Dept. of Pathology, BJ Medical College, 1 Endocrinology 1 Day
Ahmedabad
42
No. Institution Observers GCRI Department Duration
60 Dept. of Pharmacology & Toxicology, 1 Pathology 6 Days
Zydus Research Centre, Ahmedabad
61 Dr. Dinesh Rathod, VS General 1 Research Divisions 12 Days
Hospital, Ahmedabad
62 Dr. MGR Deemed University, Chennai 1 15 Days
63 Dr. Nighat Tirmizi 1 Research Division 25 Days
64 Government Engineering College, 3 Research Divisions 27 Days
Gandhinagar Nuclear Medicine
65 Government Polytechnic, Gandhinagar 3 Radiodiagnosis
Radiotherapy
Physiotherapy
Operation Theatre
66 Human Genetics Dept., School of 9 Research Divisions 13 Days
Sciences, Gujarat University,
Ahmedabad
67 Industrial Training Institute, 17 Research Divisions 13 Days
Gandhinagar Nuclear Medicine
Radiodiagnosis
Radiotherapy
Physiotherapy
Operation Theatre
Pathology
68 Institute of Research in Biotechnology & 8 Research Divisions 30 Days
Allied Sciences, New Vallabh
Vidyanagar
69 Kadi Sarva Vishwavidyalaya, 18 6 Days
Gandhinagar
70 Karunya University, Coimbatore 1 17 Days
71 KM Shah Dental College and Hospital, 3 Microbiology 56 - 90
Vadodara Research Divisions Days
72 Life Science Dept., School of Sciences, 8 Research Divisions 20 Days
Gujarat University, Ahmedabad
73 Medical Officers 22 COC, Vasna 1 Day
74 Mahadev Desai Social Work College, 3 OPD and other 72 - 110
Gujarat Vidyapith, Ahmedabad Departments Days
75 Maharshi Dayanand Saraswati 6 Research Divisions 26 Days
University, Ajmer
76 Mehsana Urban Bank Institute of Bio- 12 23 - 27
sciences, Ganpat University, Kherva Days
77 MG Science Institute, Ahmedabad 22 15 -17
Days
78 Microbiology Dept., School of Sciences, 1 20 Days
Gujarat University, Ahmedabad
79 Mr. Yashpalsinh Raj 1 30 Days
80 Ms. Priti Solanki 1 31 Days
43
No. Institution Observers GCRI Department Duration
81 Netaji Subhash Institute of Technology, 1 Research Divisions 30 Days
Delhi
82 Nirma University of Science & 5 28 Days
Technology, Ahmedabad
83 PS Science College, Kadi 8 16 Days
84 Science College, Visnagar 50 1 Day
85 Sheth MN Science College, Patan 1 20 Days
86 St Xavier’s College, Ahmedabad 13 12 - 31
Days
87 Swami Vivekanand College of 1 Research Divisions 29 Days
Engineering, Indore Nuclear Medicine
88 UV Patel College of Engineering, 3 Radiodiagnosis 49 Days
Kherva Radiotherapy
Physiotherapy
Operation Theatre
89 VVP Engineering College, Rajkot 6 Visit 1 Day
90 Zoology Dept., School of Sciences, 4 Research Divisions 27 Days
Gujarat University, Ahmedabad
Nursing Institutions
91 School of Nursing, LG Hospital, 20 ICUs, OTs, OPDs, 1 Day
Ahmedabad Wards,
92 College of Nursing, Civil Hospital, 20 Physiotherapy 30 Days
Ahmedabad
93 FHW School, RR General Hospital, 20 1 Day
Limbadi
94 School of Nursing, Civil Hospital, 66 30 Days
Ahmedabad
95 Sindhi Institute of Nursing, The Gujarat 40 ICUs, OTs, OPDs, 30 Days
Research & Medical Institute, Wards,
(Rajasthan Hospital), Ahmedabad Physiotherapy
96 School of Nursing, Civil Hospital, 79 1 Day
Ahmedabad
97 School of Nursing, General Hospital, 18 30 Days
Nadiad
98 School of Nursing, Smt SCl General 1 Day
Hospital, Saraspur, Ahmedabad
99 School of Nursing, ESIS, Bapunagr 1 1 Day
100 Govt. General Hospital, Surendranagar 13 7 Days
101 General School of Nursing, 20 6 Days
General Hospital, Mehsana
Total Institutions = 101 Observers = 953
44
Dissertation Work:
Thirty-one students from sixteen institutions did dissertation for MSc/ MPharm/ MPhil/
BTech/ MTech/ BE degree at our institute.
Department / Programme Subject Institute
Division (Students)
Microbiology MSc Identification of candida MB Patel Science College,
Dissertation albicans and other candida SP University, Vallabh
species from cancer patients Vidyanagar
(6)
Study of Klebsiella Spp.
Emergence of non-lactose
fermenting bacilli causing
hospital acquired infection
Comparison of AST by disc Bio-technology Dept.,
diffusion and MIC among the SP University, Vallabh
isolates of Vidyanagar
enterobacteriaceae group
causing infection in cancer
patients
Study of urinary tract
infection
Study of staphylococcus Dept. of BioSciences, SP
Spp. from the cancer patient University, Vallabh
Vidyanagar
Cell Biology MSc Study of genetic Dept. of Biotechnology,
Dissertation (1) rearrangements in chronic M & N Virani Science
myeloid leukemia with College, Saurashtra
molecular cytogenetic tools University, Rajkot
MPhil Cytogenetic analysis in Dept. of Biomedical
Dissertation (2) clinical management of Technology, Gujarat
chronic myeloid leukemia University, Ahmedabad
patients
Cytogenetic study of Dept. of Zoology, Gujarat
leukemia University, Ahmedabad
Molecular MPharm Tumor markers CA 19-9 and SK Patel College of
Endocrinology I Dissertation (2) CEA in serum as well as Pharmaceutical Education
pancreatic juice in pancreatic and Research, Ganpat
carcinoma Vidyanagar, Kherva
p27 in breast carcinoma
Molecular MSc Stat1 mRNA expression in
Endocrinology II Dissertation (2) breast cancer
Stat3 mRNA expression in DY Patil Institute of
breast cancer Biotechnology &
Bioinformatics, Belapur,
Navi Mumbai
Biochemistry MSc A study on GSTM1 null Biochemistry Dept., Institute
Research Dissertation (3) genotype in oral cancer of Science, Nirma
patients University
45
Department / Programme Subject Institute
Division (Students)
Biochemistry Clinical significance of Biochemistry Dept., Institute
Research protein profiling in multiple of Science, Nirma
myeloma patients University
Role of MMPs in metastasis
of cervical cancer
MTech Study of molecular markers DY Patil Institute of
Dissertation (1) in oral cancer Biotechnology &
Bioinformatics, Belapur,
Navi Mumbai
MSc Role of LDH in leukemia Biotechnology Dept.,
Dissertation (1) patients Vikram Univrersity, Ujjain,
MP
Receptor & Growth MPhil IGF-I: A marker in human Dept. of Life Sciences,
Factor Lab Dissertation (1) breast cancers Gujarat University,
Ahmedabad
MSc ER PR in breast carcinoma Biotechnology Dept.,
Dissertation (3) Vikram University, Ujjain,
MP
MMP-9 in human Biotechnology Dept., SP
meningioma University, Vallabh
Vidyanagar
MMP-2 in human glioma Biotechnology Dept., Rajiv
Gandhi College, Satna, MP
BTech MMP-2 as a prognosticator Biotechnology Dept.,
Dissertation (1) in breast carcinoma SBCBE, VTT University,
Vellore
BE Role of IGFBP-3 in breast Biotechnology Dept., VVP
Dissertation (1) cancer Engineering College, Rajkot
Immunohisto- BTech Expression of p53 protein in Dept. of Biotechnology,
chemistry Dissertation (1) head and neck cancer Sathyabhama University,
Chennai
MSc A study of markers of Dept. of Biosciences, SP
Dissertation (1) proliferation and University, Vallabh
angiogenesis in breast Vidhyanagar
cancer by
immunohistochemical
localisation
MPharm A study of vimentin and SK Patel College of
Dissertation (4) cytokeratin expression in Pharmaceutical Education
breast cancer by and Research, Ganpat
immunohistochemistry Vidyanagar, Kherva
A study of Her-2 neu
expression in breast cancer
by immunohistochemistry
46
Department / Programme Subject Institute
Division (Students)
Immunohisto- A study of p53 expression in SK Patel College of
chemistry leukemia by flow cytometry Pharmaceutical Education
Clinical significance of and Research, Ganpat
immunophenotyping features Vidyanagar, Kherva
of blasts in acute leukemia
by flow cytometry
Medicinal MSc Bioinformatics Laboratory of
Chemistry & Dissertation (1) Analysis of catalytic activity Bioinformatics, Dept., of
Pharmacogenomics of MMP-1: A bioinformatics Botany, Gujarat University,
approach Ahmedabad
(J3) Professional Training to Doctors and Scientists (Conferences, Workshops):
As a part of professional training efforts several scientific meets were organised during
the year. Some of them are joint efforts with the professional bodies.
No. Conference/Workshop/Seminar Organisers Date
Organised
1 2nd launch multi-institutional training Dr. Pankaj Shah May 17-25,
programme in Molecular Biology and Dr. Shilin Shukla 2007
Bioinformatics for teachers and Dr. Prabhudas Patel
researchers of Gujarat Biochemistry Research
2 Symposium on Lysosomal Storage Dr. Pankaj Shah July 9, 2007
Disorders: Helping Patients with Rare Dr. Shilin Shukla
Genetic Diseases co-organised with Dr. Sonal Bakshi
Genzyme CEE, Germany Cell Biology
3 GCRI ASCO Highlights 2007 Dr. Pankaj Shah July 21 and 28,
Dr. Kirti Patel 2007
Dr. Shilin Shukla
Dr. Apurva Patel
Dr. Sonia Parikh
Medical Oncology
4 Clinical Excellence Programme Dr. Pankaj Shah July 31, 2007
Dr. Kirti Patel
Dr. Shilin Shukla
Dr. Bharat Parikh
Medical Oncology
5 CME on Surgical Pathology – 2007 and Dr. Pankaj Shah September 8,
Launching of Gujarat Cancer Atlas Dr. Kirti Patel 2007
Project Dr. Manoj Shah
Dr. Priti Trivedi
Dr. Dhaval Jetly
Pathology
6 CME on Retinoblastoma Dr. Pankaj Shah September 22,
Dr. Kirti Patel 2007
Dr. Shilin Shukla
Dr. Harsha Panchal
Medical Oncology
7 Seminar on Current Trends in Molecular Dr. Pankaj Shah October 3, 2007
Biology and Clinical Drug Trials & Dr. Shilin Shukla
Poster Competition Dr. Hemangini Vora
Dr. Neelam Shah
Immunohistochemistry &
Molecular Endocrinology II
47
No. Conference/Workshop/Seminar Organisers Date
Organised
8 International Standards for Infection Dr. Pankaj Shah October 7, 2007
Prevention Focusing on Surgery Dr. Kirti Patel
Related Infections Dr. Parijath Goswami
Microbiology
9 Workshop on ‘Real Time PCR’ in Dr. Pankaj Shah November 27,
collaboration with Foundation for Dr. Shilin Shukla 2007
Research in Genetics and Dr. Sunil Trivedi
Endocrinology (FRIGE) Receptor and Growth
Factor Lab
10 Natural compounds in the management Dr. Pankaj Shah December 3,
of cancer Dr. Shilin Shukla 2007
Dr. Rakesh Rawal
Medicinal Chemistry &
Pharmacogenomics
11 GenDioT, Training Programme in Dr. Pankaj Shah December 18 –
Genetic Diagnostics Dr. Shilin Shukla January 7, 2008
Dr. Sonal Bakshi
Cell Biology
12 Pre-conference event CCRE Dr. Pankaj Shah February 6-8,
(Continuing Cancer Research Dr. Shilin Shukla 2007
Education) and 27th Annual Convention Dr. Sunil Trivedi
of Indian Association for Cancer Receptor and Growth
Research Factor Lab
(J4) Professional Training to Paramedics (Technological Courses)
Diploma in Medical Laboratory Technologists course was carried out for MLT students
of the batch 2007-2008, by Course Coordinators Dr. Priti Trivedi, Associate Professor of
Pathology; Dr. Shilin Shukla, Hon. Deputy Director (Research & Education Services); Dr.
Pankaj Shah, Hon. Director, GCRI; Shri Prashant Kinarivala, General Secretary, GCS; Dr.
Manoj Shah, Professor of Pathology; Dr. Parijath Goswami, Professor of Microbiology; and Dr.
Dhaval Jetly, Associate Professor of Pathology.
A similar Medical Radiology Technologists course is also carried out by Course Co-
ordinator Dr. Kirti Goswami, Professor of Radiodiagnosis, under the guidance of Dr. Pankaj
Shah, Hon. Director, and Dr. Shilin Shukla, Hon. Deputy Director (Research & Education
Services).
(J5) Community Education and Awareness Programmes
Regular Community Educational Programmes are arranged with the joint efforts of the
Gujarat Cancer Society on the occasion of Anti-Tobacco Day, Cancer Victory Day, Tobacco Holi
Day, Rakshabandhan, Uttarayan (Kite Flying) etc. Moreover, a free visit to permanent exhibition
for public and students is housed at COC, Vasna. All these efforts help to promote concepts of
good health in the society and strengthen the fight against cancer.
(J6) Cancer Information Centre
During the year, books on general information about cancer, treatment of cancer and for
public awareness were either sold or distributed free of charge at the above centre.
No. Books Total
1 Gujarati Books 4390
2 Hindi Books 1393
48
No. Books Total
3 English Books 988
(J7) Staff Training - Intramural and Extramural
As a part of staff training, nursing and other staff was also exposed to systemic training
programme that related to hospital infection control. This year 12 doctors and 5 other staff
members of our Institute were given support and encouraged for training. The training areas
included Review Course and Scientific Workshops.
No. Name, Designation, Date Event
Division/ Department
1 Dr. Geeta Joshi, Professor, April 9-14, 2007 PGDHHM, BJ Medical College,
Anaesthesiology June 25-30, 2008 Ahmedabad
October 1-10,
2007
2 Dr. Dhruti Desai, RMO April 16-21, 2007 Workshop on Right to
Information Act, Ahmedabad
Management Association,
Ahmedabad
3 August 27-31, Hospital Management
2007 Programme, IIM, Vastrapur,
Ahmedabad
4 Dr. Dipak Rathod, RMO April 23-29, 2007 Leadership Training for
Community - Based Cancer
Control Programme, New Delhi
5 Dr. Parimal Jivrajani, Assistant March 1-10, 2008 Fourth Short Course in Health
Professor, Community Oncology & Data Management and
Medical Records Statistical Software, Dept. of
Biostatistics, Christian Medical
College, Vellore
6 Dr. Chaitanya Shroff, Assistant June 6-July 30, Gen. Bilimoria - ICON
Professor, Surgical Oncology 2007 Fellowship 2007, Liverpool
Hospital, Liverpool, UK, under
Dr. Postan
January 24-25, Hands on training in post-
2008 laryngectomy voice
rehabilitation including provox
system, TMH, Mumbai
7 Dr. Shankar Reddy, Resident, June 21-23, 2007 6th MRI Teaching Course,
Radiodiagnosis Nanavati Hospital, Mumbai
8 Dr. Murali Krishnan, Resident,
Radiodiagnosis
9 Dr. Prakash Vasani, Resident,
Radiodiagnosis
10 Dr. Shikha Pandhi, Assistant June 21-23, 2007 6th MRI Teaching Course,
Professor, Radiodiagnosis Nanavati Hospital, Mumbai
11 Mrs. Rekha Patel, X-ray August 20-25, Training Course on
Technician 2007 Radiological Safety for
Radiation Therapy Technologist
BARC, Mumbai
49
No. Name, Designation, Date Event
Division/ Department
12 Dr. Mudit Agarwal, Assistant November 1-30, UICC - ICRETT Fellowship
Professor, Surgical Oncology 2007
13 Mr. Tushar Bopche, Radiophysicist September 28-29, Quality Assurance in High
14 Dr. Jaiprakash Neema, Professor, 2007 Precision Radiotherapy for
Radiotherapy Clinicians, Physicists and
Technologies, TMH, Mumbai
15 Dr. Tarak Patel, Medical Officer December 14-19, Training Programme of NACO,
(Blood Bank) 2007 BJ Medical College,
Ahmedabad
March 14, 2008 State Level Workshop about
16 Dr. Rima Kusumgar, Medical NABH accreditation, SIHFW,
Officer (Transfusion Medicine) Sola, Ahmedabad
17 Mr. Bharat Patel, Electronic July 9-14, 2007 Training-Switchgear
Assistant (Supervisor Electrical) Maintenance Workshop, Larsen
18 Mr. Ashok Joshi, Wireman & Toubro Limited, Pune
19 Mr. Narendrasinh Chavda, February 26-28, Human & Institution
Hospital Administrator 2008 Development Programme,
Ahmedabad
March 26-28, 2008 Management Development
Programme, Bangalore
(J8) Hospital Day – Research and Educational Aspects
Eminent National Scientists were honoured with Dr. T. B. Patel Oration Award and Shri
Ramniklal J. Kinarivala Cancer Research Award. Young Scientists, Clinical Departments and
Research Divisions were encouraged with Dr. T.B. Patel Research Medals, Smt. Vibha Mehta
and Smt. Vimla Agrawal Rotating Trophies.
The Hospital Day celebrated on April 19, 2008 with a festive and jubilant mood. The main
events included scientific awards, orations and felicitations in the field of Cancer Research
followed by cultural programme by the staff members. Dr. Nathubhai Patel, Founder Director of
Cardiology Institute, and Dr. JN Patel, Former Dean of BJ Medical College, were the Guests of
Honour for this occasion. The following were the awardees:
1) Dr. T. B. Patel Oration awarded to Dr. KS Gopinath, Director HCG, Bangalore Institute of
Oncology, Bangalore. He delivered a lecture on ‘Beyound mere feasibility challenges in oncology
to oncologists’.
2) Late Shri Ramniklal J. Kinarivala Cancer Research Award conferred to Dr. T. Rajkumar,
Director & Scientific Director, Cancer Institute (WIA), Adiyar, Chennai. He delivered a lecture on
‘Recent advances in molecular oncology - Cancer Institute (WIA) experience’.
3) Dr. T. B. Patel Research Medals awarded to Junior Scientists
Medal Clinical Wing Research Wing
Gold Medal Dr. Pooja Nandwani Patel -
(Radiotherapy)
Silver Medal Dr. Anjana Chauhan Ms. Hetvi Patel
(Gynaecological Oncology) (Biochemistry Research)
50
4) Vimla Agrawal Trophy (Clinical Department) for maximum publications
Surgical Oncology Department
5) Vibha Mehta Trophy (Research Division) for maximum publications
Biochemistry Research Division
(J9) Clinical Meetings
Regular bimonthly academic and scientific clinical meetings are arranged at Cama Hall,
GCRI, on 2nd and 4th Saturdays. Dr. Neelam Shah, Senior Scientific Officer, is the coordinator of
this activity and during the year, a large number of clinical and research subjects are discussed.
Total 38 Clinical and Journal presentations were discussed at the Clinical Meetings from April
2007 to March 2008.
(J10) Activities of the Scientific Research Committee
The Scientific Research Committee (SRC) functions throughout the year to promote,
facilitate and maintain the basic and applied research in the field of cancer under the
chairmanship of Dr. Pankaj Shah (Chairman, SRC), Hon. Director, Gujarat Cancer & Research
Institute, and Dr. Shilin Shukla, Hon. Deputy Director (Research & Education Services) and
Member-Secretary of the Scientific Research Committee. All the research activities were
scrutinised, approved and monitored by the Scientific Research Committee and also by the Ethics
Committee, both of which met regularly every alternate months or earlier, if needed. At the SRC
meeting, scientific details and other routine issues are discussed. The office bearers of Scientific
Research Committee also met in the year several times as and when required.
At the annual meeting, in the presence of invited experts, all the new proposals as well as
the on-going projects were discussed and were approved with budgetary recommendations. At
the 6 monthly meeting, new and ongoing projects were also discussed and approved for
continuation.
Annual Meeting of the Scientific Research Committee was held once. However, there
were as a part of scientific review committee, 4 scientific meetings (April 13 and August 11, 2007,
January 25 and February 15, 2008) and 4 ethics committee meetings (April 28, August 18 and
October 13, 2007, and February 6, 2008) were held. The Ethics Committee Meetings were held
under the chairmanship of Hon’ble retired Justice Shri AP Ravani and Member-Secretary Dr.
NL Patel. Invited Members were Shri Naranbhai Patel, Dr. Pankaj Shah, Dr. Shilin Shukla, Dr.
Kirti Patel, Dr. Rajendra Dave, Smt. Bhartiben Sunderbhai, Shri Madhav Ramanuj, and Shri
Bharatbahi Kshtriya.
(J11) GCS Research Bulletin
As GCS Research Bulletin, academic and research work of Research Divisions and
Clinical Departments of the Gujarat Cancer and Research Institute regularly published by GCS.
Dr. Sunil Trivedi, Dr. Bharat Parikh and Dr. Pariseema Dave were the editors of the bulletin.
(K) LIBRARY
Staff Pattern: It has one Librarian, one Assistant Librarian and one Clerk.
Services: GCRl Library caters to the needs of staff members with its resources. The
regular and selective addition of books and journals to this library has enriched its collection and
made it a good reference centre particularly in the field of oncology. Through this, library has a
vast collection of books and journals of oncology. Library covers area about 4,450 Square Feet.
The library provides following services: Lending, Reference Services, Xerox Services and
Interlibrary Loan. Workshop, Conference and Training details are displayed on the Notice Board.
Library introduced free BSNL Broadband Internet Services with Static IP, 10 terminals to
their faculty members. Database search facility involving the CD Rom and online database were
used extensively during the report year. We provide more service including article search on
various subject to the postgraduate medical students, researchers and also outside members of
this library. The Library met entire professional, official and project photocopying requirements of
all divisions.
51
Service Output: Library is equipped with modern books on various subjects on oncology.
During the report year, collection of books and journals were increased. Total numbers of the
books are 2650 and 100 subscribed Journals. Total holding of the bound volumes are about
25,000 from the year 1965 onwards. The library is being utilized by the faculty members of GCRl
and as reference library of the P.G. students of various medical institutes of the State,
Ahmedabad city and scientific community. The number of library users is continuously increasing.
Digital Library: GCRl library has taken up initiative towards archiving the Open Access
Journals related to cancer available on net digital media for offline browsing for staff and visiting
students from other colleges and universities. During reporting year digital collection of books and
journals is about 265.
Wifi facility is installed in library and research wing for internet and data sharing. Library
have purchased “SOUL” Software for automation and work is under progress.
Library Committee
Chairman Dr. Pankaj Shah, Hon. Director, GCRI
In-charge Co-Chairman Dr. Shilin Shukla, Hon. Dy. Director (Research & Education
Services)
Co-Chairmen Dr. Rajendra Dave, Hon. Dy. Director (Surgical Services)
Dr. Kirti Patel, Hon. Dy. Director (Medical Services)
Professor In-charge Dr. Rakesh Vyas, Professor & Head, Radiotherapy
Member Secretary Dr. Asha Anand, Additional Professor, Medical Oncology – I
Members Dr. Ava Desai, Additional Professor, Gynaecological Oncology – I
Dr. Kiran Kothari, Professor, Surgical Oncology – III
Dr. Manoj Shah, Professor, Pathology
Dr. Geeta Joshi, Professor, Anaesthesiology
Dr. Kirti Goswami, Professor & Head Radiodiagnosis
Dr. Sunil Trivedi, Senior Scientific Officer, Receptor and Growth
Factor Lab
Dr. Rakesh Rawal, Junior Scientific Officer, Medicinal Chemistry &
Pharmacogenomics
Shri Narendrasinh Chavda, Hospital Administrator
Shri Naresh Shah, Librarian
(L) EDUCATIONAL GRAPHICS & MEDICAL PHOTOGRAPHY
Staff Pattern: Department has two well-experienced staff members one Chief Artist and
one Photographer cum Darkroom Technician.
Services: The department plays an important role in catering all the needs of Medical
Photography and Educational Graphics of the institute for the purpose of clinical, educational and
public awareness activities. Publication and printing designs are the main stay of this department.
This is in the form of graphic designing, photographs, video, posters, folders, etc. Besides this,
the department is preparing the presentation materials and handouts for scientific meets. The
department is equipped with digital in-house production facility of educational material in CD form.
Service Output:
No. Details of Work Done Number
1 Clinical Photographs 2480
2 Photographs (General/Scientific Events) 4300
Public Services: Participation in all the GCRI/GCS public awareness campaigns.
52
IV. CANCER EPIDEMIOLOGY & COMMUNITY ONCOLOGY
(M) DEPARTMENT OF CANCER EPIDEMIOLOGY & COMMUNITY ONCOLOGY
GENERAL STATISTICS OF REGISTERED CASES
No. Details of Work Done Year Year
2006 2007
1 Total new cases registered (Cancer & Non-cancer) 20,381 21,488
Adult cases 19,476 11,705
Paediatric cases 905 999
2 Total number of outdoor patients visited 2,06,503 2,12,813
3 New admissions during the year 20,027 20,187
4 Inpatient days 1,80,578 1,83,481
5 Average inpatient stay 9.02 9.09
6 Strength of beds 650 650
7 Death during the year 1,008 1,041
8 Haematological investigations 6,32,159 7,21,675
9 Biochemical investigations 4,25,638 4,72,793
10 Bacteriology investigations including serology 7,006 7,341
11 Cytological investigations 12,899 12,438
12 Histological examinations 71,923 79,729
13 Bone marrow examinations 3,234 3,290
14 Biopsy procedures (Other than endoscopies & BM Bx) 3,632 3,472
15 Total BT given to the patients 13,875 14,409
16 Total Plasma/PRP given to the patients 10,433 9,667
17 Imaging & Radiological Investigation
(i) MMR Barium Swallow and other X-rays 48,060 44,564
(ii) Ultrasound examinations 15,391 15,037
(iii) CT Scan 6,739 8,816
(iv) MRI 1,138 1,684
(v) Mammograms 2,446 2,742
18 Radiation Treatment
(i) Brachytherapy 1,387 1,162
(ii) Cesium Teletherapy - -
(iii) Cobalt Teletherapy 1,710 2,033
(iv) Linear Accelerator 4,229 3,997
(v) Mould prepared for planning 1,962 1,865
(vi) Simulator treatment planning 6,322 5,662
19 Surgical Operations
(i) Major 3,289 3,472
(ii) Minor 9,358 10,433
(iii) IVTC 3,219 3,266
20 Neurosurgical operations 529 491
21 Nuclear Medicine (Isotope)
53
No. Details of Work Done Year Year
2006 2007
(i) Thyroid Scan 184 228
(ii) Bone Scan 1,179 1,464
(iii) Liver Scan 7 3
(iv) Kidney scan 246 405
(v) RI Therapy 46 108
22 RIA investiations 14,923 17,368
23 Immunohistochemistry and Immunophenotyping 7,114 16,242
24 Biochemical investigations (Research wing) 1,796 1,966
25 Karyotyping and FISH (Research wing) 1,187 1,487
26 Physiotherapy treatment 18,275 18,838
27 Total number of chemotherapeutic procedures 22,836 25,818
28 Bone Marrow Transplants 10 13
29 Total FFP/SDP given to the patient 5,681 6,354
30 ECG 5,766 6,822
Staff Pattern: There are one Assistant Professor, one Medical Record Officer, one
Medical Record Keeper, two Statistical Assistants, one Photographer cum Artist, one Store
Keeper cum Cashier, three Senior Clerks, six Junior Clerks, three Case Writers, two Record
Clerks, two Junior Data Entry Operators, and three Field Workers.
Services: This department is a very important section of the institute. It maintains the
records of newly registered cases as well as old (follow-up) cases.
Service Output:
No. OPD cases Number
1 New 21,488
2 Old 2,12,813
Activities: Research: (a) Hospital Based Cancer Registry: The department has been
maintaining Hospital Based Cancer Registry since long. (b) ICMR Project: Rural Cancer
Registry – Ahmedabad District under the network of National Cancer Registry Programme has
started from January 2004. (c) ICMR Project: Department has started the project 'Patterns of
care and survival studies of Cancer Cervix, Cancer Breast, and Head & Neck Cancer from
January 2006 under the network of National Cancer Registry Programme. (d) Government of
India Project (Ministry of Health & Family Welfare): Under National Cancer Control
Programme, Ahmedabad District Cancer Control Programme has been started from 2006.
(e) ICMR Project: Population Based Cancer Registry - Ahmedabad Urban Agglomeration Area
has started from January 2007 under the network of National Cancer Registry Programme.
(f) Government of Gujarat Project: Development of an Atlas of Cancer in Gujarat has started
from 2007.
Under the banner of National Cancer Control Programme of Govt. of India, the
department had orgainsed a conference on June 7, 2007 and total 21 delegates attended the
same.
54
Meeting / Seminar / Workshop / Event Organised:
Title of the Meeting Date Under the banner of which No. of
Organisation/Association delegates
National Cancer Control June 7, National Cancer Control 21
Programme 2007 Programme
Seminar on Detection of Common July 15, Ahmedabad District Cancer 76
Cancer in Women in India- 2007 Control Programme
Orientation of Gynaecologist on
VILI Test
Workshop on Common Cancer in January 74
Women 11, 2008
Gram Mitra Arogya Shibir May 5, 146
2007
World No Tobacco Day May 31, 254
2007
Training Organised: Depatment had organised cancer awareness training for Medical
and Paramedical personnel under Ahmedabad District Cancer Control Programme and National
Cancer Control Programme of Government of India. The first step towards the control of any
disease is to create awareness by educating health care provider about the risk factors, early
symptoms, signs and preventive steps to be undertaken. The health care provider i.e. Health
Workers, Health Supervisors, Gram Mitra Arogya, Anganwadi and Teda Ghar Workers, and Link
Workers work in the community literally at the door step and are trained how to effectively
communicate about cancer at grass root level.
There is a need to increase awareness among community regarding prevention and early
detection of cancers. This can be addressed by proper training and sensitisation of health care
providers. Thus Cancer Awareness Training was initiated to achieve following objectives.
1. Creating common cancer awareness among health professionals and thereby in the
community.
2. Early detection of common cancers through capacity building and technical
assistance at district level (PHCs, CHCs and District Hospitals), and up gradation of every
health care provider on an ongoing basis is necessary to achieve the ultimate objective of
every PHC as a cancer control clinic to:
i. Advise for tobacco habit cessation
ii. Propagate screening and cancer related check-up and
iii. Palliative care
Training attended by various health personnel is shown in the table below.
No. Taluka Health Gram Mitra Anganwadi Teda Ghar/ Link
Worker Arogya Worker Worker
1 Viramgam 39 30 145 0
2 Detroj 27 31 77 0
3 Mandal 24 10 67 0
4 Sanand 64 17 136 0
5 Bavla 23 10 115 5
6 Urban(Unnat) 0 0 7 90
7 Dholaka 45 26 210 1
8 Dhandhuka 35 11 - 4
9 Barvala 13 3 33 10
55
No. Taluka Health Gram Mitra Anganwadi Teda Ghar/ Link
Worker Arogya Worker Worker
10 Ranpur 13 4 32 -
11 Daskroi - - - -
12 Urban - - 926 -
Total 283 142 1748 110
IEC (Information, Education, Communication) activities:
IEC activities were commenced to achieve the following objectives:-
1. Informing people at village level about cancer, its causes and natural history.
2. Promoting common cancer screening for women in the target group.
3. Promoting screening among tobacco users.
4. Increasing awareness of signs and symptoms of cancer.
5. Reducing ignorance, fear, embarrassment and stigma related to cancer.
To achieve the above objectives IEC activity work plan included.
1. Street play on tobacco by TV Artist Mr. Archan Trivedi,
2. Group discussion on cancer by gathering villagers at a common place in a village and,
3. Meeting of important local leaders like Sarpanch of the village and School Principals.
During each IEC activity on an average 4-5 villages were covered. A total of 152 villages
were covered for IEC in the 2nd year of ADCCP. The visit consisted essentially of creation of
awareness on risk factors, and early warning signals, thus empowering the population to seek
good life styles and health related examination to detect and diagnose the disease in early stages
and undergo treatment.
Increased knowledge is associated with greater participation rates in cancer screening
activities. So, public education was the ardently pursued activity. Self examination methods were
emphasized, particularly of oral cavity with need for quitting tobacco. A method of Breast Self
Examination was also propagated among women group.
Awareness about cancer was created by personal discussion, group discussion, and
distribution of publicity material like pamphlets, posters, flip charts, exhibition and audio-visual
programmes, especially targeted to the more vulnerable sections of the society.
As a part of project activity, TV artist Mr. Archan Trivedi and his team performed street
plays in the village covered of IEC. The theme of this play was to create awareness about
tobacco related cancers and effectively convey message of tobacco hazards amongst general
population.
Cancer Detection Programme:
Following IEC activity Cancer Detection Camp was organised at PHC level of each
Taluka. This cancer screening and detection programmes addressed normal people and were
undertaken in a campaign mode i.e. IEC activities preceded screening camps. It was found that a
cancer screening camp is most productive if conducted on following day after IEC.
The objectives of Cancer Detection Camp were:-
1. Early detection of common cancers in women: Breast and Cervix cancers
2. Early detection of common cancers in men: Head and Neck cancer
3. Counseling of suspicious patients detected in camp
4. Tobacco cessation counseling of people attending camp
5. Educating villagers through cancer exhibition
Follow-up work of camp patients at GCRI:
56
This included mainly counseling of:
1. Suspicious patients attending GCRI for diagnostic confirmation of the disease.
2. Confirmed cancer diagnosed patients to comply with the treatment.
Any suspicious or precancerous condition were motivated and counseled to attend GCRI
for diagnostic confirmation. Once the patient attends GCRI hospital is re-counseled.
Counseling of confirmed cancer patient to complete treatment: Due to lack of awareness
about cancer paucity of information regarding early signs and symptoms of the disease and
ignorance about the treatment modalities amongst lay people causes fear and feeling of
helplessness. As cancer hospitals are based only in big cities a person coming from a rural area
faces many problems in a big city. Consuming of such people is essential. It is also true that at
times treatment. Often patients do not complete treatment for various reasons especially if
symptomatic relief is obtained by the patient. Thus counseling of patient is an important aspect to
help patient cure his cancer.
Public Services: Department is actively involved in various GCRI events like Anti
Tobacco day, Kite flying day, Hospital day, National Cancer Awareness day etc. Under the
Ahmedabad District Cancer Control Programme, a programme 'Sangeet Sandhya' was
organised. This programme was held at Gujarat Law Society – Auditorium, Law Garden,
Ellisbridge, Ahmedabad, on September 24, 2007. Hemant Chauhan was the main attraction of
this programme. He sang songs particularly on tobacco – alcohol deaddiction and cancer
awareness. These songs were written by Shri Vitthalbhai. Whole programme was recorded for
preparation of CDs and these CDs will help in community based IEC activities. Along with
'Sangeet Sandhya', blood donation camp, anti-tobacco and cancer awareness exhibition also held
at programme site. Department has participated in 95 cancer awareness exhibitions and camps
as well as in three public lectures.
(N) COMMUNITY ONCOLOGY CENTRE (COC)
The COC, Vasna, houses several activities. Prominent among them are the (1) Hospice
Service, (2) Permanent cancer as well as tobacco-de-addiction related exhibition, (3) Cancer
related health check-up and, (4) Medicinal plantation.
(N1) Hospice Service
At COC, terminally ill patients with cancer are given shelter, warmth and palliative care as
a part of Hospice service. The details are given in (H5) – vide supra.
(N2) Cancer Awareness & Anti-Tobacco Exhibition
It houses permanent exhibition for cancer education and awareness. This year 6,179
visitors including students and teachers from schools, colleges and other oraganisations visited
COC.
(N3) Health Check-up Plan
Regular Health Check-ups are carried out for early detection of cancer at this centre.
Different diagnostic facilities for Cancer Screening are also available i.e. Mammography, X-Rays,
Sonography, Pap smear, FNAC, Biopsy etc. During this year, total 2,023 males and 3,688
females (total 5711) were screened at Vasna Centre.
57
Service Output:
Procedure Parameter Number Procedure Parameter Number
Cases Male 2023 FNAC Total 25
Screened Female 3688 Normal 6
Total 5711 Abnormal 10
Normal 4573 Positive 9
Abnormal 417 Sonography Total cases 5711
Mammo- Total 3536 Pap Smears Total 3745
Graphy Normal 3054 Normal 1933
Fibroadenoma 139 Inflammation 1787
Fibrocystic 295 Dysplasia 13
Disease Positive 2
Ref. to GCRI 10
Nipple Discharge Total cases 24
Malignancy 48 Positive Cases 48
of Malignancy
(N4) Development of Medicinal Plant Park
From VIKSAT Group, a Garden with 130 plantations was developed. These plants are
having some Herbal Medicinal importance, which might be useful in treatment of the cancer or its
manifestation.
58
V. OUT-REACH ACTIVITIES
(O) CANCER DETECTION CAMPS, BLOOD DONATION CAMPS, AND CANCER
AWARENESS EXHIBITION
The Institute along with the Gujarat Cancer Society organises regular cancer detection camps
and cancer awareness exhibition in various parts of the State. Many a times they are coupled with
blood donation camps. The Institute had attended 95 camps at following places. There were 83
voluntary blood donation camps and collection of 3430 blood bags.
Cancer Detection Camps: 63 places and 95 camps
Military Hospital, Ahmedabad Cantonment, Ahmedabad (8/4/07); Yogini Vasanti Devi Smarak
Trust, Vadodara (21/04/07, 14/07/07, 20/10/07, 19/01/08); Smt. Santokba Bhagwati General
Hospital, Dholka (26/04/07, 26/07/07, 25/10/07, 24/01/08); Govt. Hospital, Dhragandhra
(28/04/07, 16/6/07, 23/6/07); Kathavada High School, Kathavada, Daskroi (29/04/07); Dawoodi
Bohra Jamaat, Aligadh, Viramgam (06/05/07); Rukmaniben Prasutigruha, Ahmedabad (09/05/07,
13/06/07, 11/07/07, 08/08/07, 05/09/07, 08/09/07, 10/10/07, 07/11/07, 05/12/07, 09/01/08,
06/02/08/, 05/03/08); Nagar Heatlh Service Centre, Kapdiwad, Hospital, Sarangpur, Ahmedabad
(12/05/07, 09/06/07, 14/07/07, 11/08/07, 08/09/07, 13/10/07, 10/11/07, 08/12/07, 12/01/08,
09/02/08, 08/03/08); Champa Vijaya General Hospital, Rampura (Bhankoda), Detroj, Ahmedabad
(26/05/07); Giriraj Complex, Ahmedabad (22/07/07, 23/07/07); Savaliya Hospital, New
Bapunagar, Ahmedabad (05/08/07, 02/09/07); Super Surgical Hospital, Navrangpura,
Ahmedabad (15/08/07); Samta Hospital, Chandlodiya, Ahmedabad (19/08/07); HQ11, Military
Station, Chiloda (25/08/07); LIC of India, Main Office, Gandhinagar (03/09/07); Karakthal
Prathmik Arogya Kendra, Karakthal, Viramgam, Ahmedabad (15/09/07); Kumarkhan Prathmik
Arogya Kendra, Kumarkhan, Viramgam (17/09/07); Manipur Prathmik Arogya Kendra, Manipur,
Viramgam (22/09/07); Aga Khan Health Service, Balwa, Amreli (22/09/07); Ansuya General
Hospital, Maninagar, Ahmedabad (23/09/07); Trent Prathmik Arogya Kendra, Mandal (24/09/07);
Prathmik Arogya Kendra, Sitapur, Mandal (29/09/07, 01/10/07); Hospital Saraswati Mandir
Complex, Junagadh (30/09/07); Shri Jalaram Arogyadham, Vasantpura, Nadod, Narmada
(30/09/07); Prathmik Arogya Kendra, Dalod, Mandal (01/10/07); Prathmik Arogya Kendra,
Rampura, Ahmedabad (06/10/07); Prathmik Arogya Kendra, Katosan Road, Ahmedabad
(08/10/07); Air Force Station, Makarpura, Vadodara (12/10/07); PHC Santhal, Sanand,
Ahmedabad (13/10/07); PHC, Jholapur, Sanand, Ahmedabad (15/10/07); PHC, Nadiad and
Vadodara (20/10/07); PHC, Upardal, Ahmedabad (20/10/07); PHC, Modasar (22/10/07); PHC,
Chekhla, Sanand (27/10/07); Agakhan Health Service, Kankariya, Ahmedabad (31/10/07);
Prathmik Arogya Kendra, Kavitha, Bavla, Ahmedabad (17/11/07); Prathmik Arogya Kendra,
Nanodara, Bavla, Ahmedabad (19/11/07); Prathmik Arogya Kendra, Bagodara, Bavla,
Ahmedabad (26/11/07); PHC, Noblenagar, Ahmedabad (08/12/07); PHC, Hansol, Ahmedabad
(10/12/07); PHC, Khodiyarnagr, Ahmedabad (17/12/07); PHC, Saraspur, Ahmedabad (22/12/07);
PHC, Ramol, Ahmedabad (29/12/07); PHC, Vastral, Ahmedabad (31/12/07); PHC, Prathmic
Arogya Kendra, Chaloda, Dholaka, Ahmedabad (19/01/08); Prathmik Arogya Kendra, Gam-
Ambaliara, Dholaka, Ahmedabad (21/01/08); Prathmik Arogya Kendra, Transad, Dholaka,
Ahmedabad (28/01/08); Prathmik Arogya Kendra, Koth, Dholaka, Ahmedabad (02/02/08);
Prathmik School, Kathada, Dasada, Surendranagar (03/02/08); Prathmik Arogya Kendra,
Vataman, Dholaka, Ahmedabad (04/02/08); Kathwada Primary School, Kathwada, Dascroi,
Ahmedabad (08/02/08); Primary Health Centre, Piple, Ahmedabad (16/02/08); Mahavir
International, Red Cross Bhavan, Dahod (17/02/08); Primary Health Centre, Dholera, Ahmedabad
(18/02/08); Primary Health Centre, Bhadiyad, Ahmedabad (23/02/08); Primary Health Centre,
Vagad, Ahmedabad (25/02/08); Primary Health Centre, Jalila, Ahmedabad (01/03/08); Primary
Health Centre, Baravala, Ahmedabad (03/03/08); Primary Health Centre, Bhimnath, Ahmedabad
(08/03/08); Air Force Station, Wadsar, Kalol, Gandhinagar (13/03/08); Primary School, Malanpur,
Patdi, Surendranagar (15/03/08); Aga Khan Health Service, Aga Khan Hostel, Botad, Bhavnagar
(19/03/08); English Medium School, Maninagar, Ahmedabad (19/03/08)
59
Blood Donation Camps: 80 places and 83 camps
National Institute of Fashion Technology, Gandhinagar (11/04/07); Pritampura Society 1, Section-
1, Girdharnagar, Ahmedabad (15/04/07); Varmora Prathmik Vidhyalaya, Mandal, Ahmedabad
(15/04/07); Motiff India Pvt Ltd, Ahmedabad (18/04/07); Raj Academy, Ambavadi, Ahmedabad
(22/04/07); Shivanand Aashram, Jodhpur Tekra, Ahmedabad (29/04/07); Ashish School, Vatva,
Ahmedabad (29/04/07); CHC Training Center, Prathmik Shala No.2, Mansa (04/05/07); Uma
Sanskar Tirth, Chandrala, Prantij (06/05/07); Shanidev Temple, Shahibaug, Ahmedabad
(12/05/07); Sun City Shopping Center, Bopal, Ahmedabad (27/05/07); Sandipani Ashram,
Porbandar (3/6/07); LIC of India, Relief Road, Ahmedabad (4/6/07); Gujarat Institute of Radio
Vibhash, Gandhinagar (10/6/07); Ramaji Mandir, Paldi, Ahmedabad (10/6/07); Municipal
Transport Service, Jamalpur, AMTS, Ahmedabad (14/06/07); GCRI Hospital Donor Day, Asarwa,
Ahmedbad (14/6/07); IDBI Bank, CG Road, Ahmedabad (02/07/07); Jaldhara Shopping Centre,
Gandhinagar (11/07/07); Jan Kalyan Sewa Trust, State Bank of India, Shahibaug, Ahmedabad
(15/07/07); Jamsanu Bandhol Gram Panchayat, Bhartiya Kishan Sungh, HH Patel High School,
Kalol, Nardipur (22/07/07); Bhartiya Kisan Sangh, Jamva Gram Panchayat, Kalol (25/07/07); MN
Shukla College of Education, Thaltej, Ahmedabad (28/07/07); Pavitrakunj Society, CTM,
Ahmedabad (29/07/07); Sadhna Ashram, Koba, Gandhinagar (29/07/07); All India Insurance
Local Self, Barfiwala Bhavan, Khanpur, Ahmedabad (14/08/07); Radhe Bunglows, Khokhara,
Ahmedabad (15/08/07); Sachin Tower, Satellite, Ahmedabad (15/08/07); Shrimali Swarnajayanti,
Brahamseva Samaj Hall, Paldi, Ahmedabad (15/08/07); Sardar Patel Seva Samaj Hall,
Ahmedabad (19/08/07); Salyasi Seva Samiti, Varjdham Haveli, Satellite, Ahmedabad (19/08/07);
Dr. Vishwas Amin, Ahmedabad (21/08/07); Ahmedabad Management Association, Ahmedabad
(21/08/07, 22/08/07, 23/08/07); L&C Mehta Arts college, Ahmedabad (24/08/07, 25/08/07); LA
Shah Low College, Ahmedabad (25/08/07); Pravin Sintex Pvt Ltd, Kalol (25/08/07); Shrinand
Nagar Vibhag-2, Vejalpur, Ahmedabad (26/08/07); LIC of India, Gandhinagar (03/09/07); HL
Institute of Computer Application, Navrangpura, Ahmedabad (06/09/07); HDFC Bank, Maninagar,
Ahmedabad (10/09/07); Kameshwar Hall, Naranpura, Ahmedabad (14/09/07); Govt. Engineering
College, Gandhinagar (22/09/07); Town Hall, Gandhinagar (25/09/07); Shree Jalaram
Arogyadham, Vasantpura, Nadod, Narmada (30/09/07); Upmanya Education College,
Ahmedabad (30/09/07); Hiraba School, Mahadev Nagar Tekra, Vastral, Ahmedabad (01/10/07);
Community Health Centre, Nardipur, Gandhinagar (02/10/07); Chuwal Gam Vikas Trust,
Sarangpur, Ahmedabad (04/10/07); Community Health Centre, Kasturbanagar, Saraspur,
Ahmedabad (07/10/07); Community Health Centre, Naranpura, Ahmedabad (10/10/07);
Community Health Centre, Lions Ground, Gandhinagar (18/10/07); Jagatdarshan Society,
Chhatral Road, Kadi (18/10/07); Shri Narayan Banglows, Thaltej Shilaj road, Ahmedabad
(21/10/07); HDFC Bank, Sarangpur, Ahmedabad (27/10/07); Indian Institute of Management,
Ahmedabad (28/10/07); Mahavit Maradge Dom, Krishnnagar, Ahmedabad (17/11/07); Lal
Bahadur Shastri Stadium, Bapunagar, Ahmedabad (21/11/07); LD Arts College, Navrangpura,
Ahmedabad (29/12/07); Kalyanpura Gam, Achara road, Viramgam (30/12/07); Subhavan
Prarthna Bhavan and Party Plot, Gulbai Tekra, Ahmedabad (30/12/07); Anjana Society Campus,
Matru Shakti Society, Bapunagar, Ahmedabad (06/01/08); Arbudgiri Society, Sabarmati,
Ahmedbad (06/01/08); Malanpur, Dashada, Surendranagar (12/01/08); Rotary Hall, Sabarmati,
Ahmedabad (26/01/08); Chandisar Prathmik School, Chandisar, Dholka, Ahmedabad (27/01/08);
Bhaleshwar Mahadev Vadi, Bapunagar, Ahmedabad (27/01/08); IIM Students Jose, Vastrapur,
Ahmedabad (02/02/08); Tatsat Society, Ambawadi, Ahmedabad (03/02/08); Home Guards,
Laldarwaja, Ahmedabad (03/02/08); Girdharnagar Secondary School, Shahibaug, Ahmedabad
(09/02/08); Bapa Sitaram Sayog Sarita Mandal, Nikol Naroda Road, Ahmedabad (10/02/08);
Sardar Patel Smark Bhavan, Shahibaug, Ahmedabad (10/02/08); Bapunagar Ahmedabad
(17/02/08); Daskoshi Kadwa Patidar Hall, Sola, Ahmedabad (28/02/08); Nima Vidhyalaya, Nava
Vadaj, Ahmedabad (02/03/08); Gurjar Kartikey Kadia Samaj, Nirnay Nagar Garnala , Chandlodiya
(02/03/08); Sector - 1 Gandhinagar (08/03/08); Navshakti Yuvak Mandal, Malanpur, Patdi,
60
Surendranagar (15/03/08); Rashtriya Blood Sewa Mandal, Khanjan Darwaja Dargah, Jamalpur,
Ahmedabad (16/03/08); Mahesana Prajapati Yuva Sansthan, Mahesana (30/3/08)
Cancer Awareness Exhibition: 57 Places and 90 Camps: Pritampura Society Section-1,
Girdharnagar, Ahmedabad (15/04/07); Shri Santram Mandir Dairy, Nadiad (19/04/07, 19/07/07,
18/10/07, 17/01/08); Yogini Vasanti Devi Smarak Trust, Geeta Mandir, Pratapnagar Vadodara
(21/04/07); Diwan Ballubhai School, Kankaria, Ahmedabad (21/04/07, 22/04/07); Kathvada High
School, Kathwada, Daskroi (29/04/07); Champa Vijaya General Hospital, Rampura, Detroj,
Ahmedabad (26/05/07); Nagar Health Service Centre, Sarangpur, Raipur, Ahmedabad (12/05/07,
09/06/07, 14/07/07, 11/08/07, 08/09/07, 13/10/07, 10/11/07, 08/12/07, 12/01/08, 09/02/08,
08/03/08); Government Hospital, Dhrangandhra, Surendranagar (23/06/07); Rukmaniben
Prasutigruha, Khokhara, Ahmedabad (09/05/07, 13/06/07, 11/07/07, 08/08/07, 05/09/07,
08/09/07, 10/10/07, 07/11/07, 05/12/07, 09/01/08, 06/02/08, 5/03/08); Savaliya Hospital, New
Bapunagar, Ahmedabad (05/08/07); HQ II Military Station, Gandhinagar (25/08/07); Kumarkhan
Prathmik Arogya Kendra, Viramgam, Ahmedabad (17/09/07); Manipur Prathmik Arogya Kendra,
Manipur, Viramgam, Ahmedabad (22/09/07); Aga Khan Health Centre, Babra, Amreli (22/09/07);
Trent Prathmik Arogya Kendra, Trent, Mandal, Ahmedabad (24/09/07); Prathmik Arogya Kendra,
Sitapur, Mandal, Ahmedabad (29/09/07); Shri Jalaram Arogyadham, Vastrapur, Nadod, Narmada
(30/09/07); Mandal Prathmik Arogya Kendra, Mandal, Ahmedabad (1/10/07); Rampura Prathmik
Arogya Kendra, Rampura, Detroj, Ahmedabad (06/10/07); Prathmik Arogya Kendra, Katosan,
Detroj, Ahmedabad (08/10/07); Kapdiwad Hospital, Raipur, Ahmedabad (13/10/07); Nadiad -
Vadodara Camp (20/10/07); Sheth P&R High School, Bhakhariya Pratij, Sabarkantha (23/10/07);
Agakhan Health Service, Kankariya, Ahmedabad (31/10/07); Prathmik Arogya Kendra, Kavitha,
Bavla, Ahmedabad (17/11/07); Prathmic Arogya Kendra, Nanodara, Bavla, Ahmedabad
(19/11/07); Prathmik Arogya Kendra, Ganfadi, Bavla, Ahmedabad (24/11/07); Prathmic Arogya
Kendra, Bagodara, Balva, Ahmedabad (26/11/07); PHC Nobal Nagar, Ahmedabad (08/12/07);
PHC Hansol, Ahmedabad (10/12/07); PHC Khodiyar Nagar, Ahmedabad (17/12/07); PHC
Saraspur, Ahmedabad (22/12/07, 24/12/07); PHC Ramol, Ahmedabad (29/12/07); PHC Vastral,
Ahmedabad (31/12/07); PHC Pitahi, Kathlal, Kheda (06/01/08); Dhandhuka Cotton Sale,
Shakhazin, Bhavnagar (09/01/08); Prathmik Arogya Kendra, Chaloda, Dholaka, Ahmedabad
(19/01/08); Prathmik Arogya Kendra, Ambaliara, Dholaka, Ahmedabad (21/01/08); Atmiya Amrut
Mahotsav Samiti, Gujarat University Ground, Ahmedabad (26/01/08); Prathmic Arogya Kendra,
Transad, Dholaka, Ahmedabad (28/01/08); Prathmik Arogya Kendra, Koth, Dholaka, Ahmedabad
(02/02/08); Prathmik Arogya Kendra, Vataman, Dholaka, Ahmedabad (04/02/08); Kathwada
Primary School, Kathwada, Dascroi, Ahmedabad (08/02/08); Primary Health Centre, Piple,
Ahmedabad (16/02/08); Primary Health Centre, Dholera, Ahmedabad (18/02/08); Primary Health
Centre, Bhadiyad, Ahmedabad (23/02/08); Primary Health Centre, Vagad, Ahmedabad
(25/02/08); Primary Health Centre, Jalila, Ahmedabad (01/03/08); Primary School, Koth, Dholka,
Ahmedabad (01/03/08); Primary Health Centre, Baravala, Ahmedabad (03/03/08); Torrent
Pharmaceuticals Ltd, Indrad, Kadi, Mahesana (07/03/08); Primary Health Centre, Bhimnath,
Ahmedabad (08/03/08); Air Force Station, Vadsar, Gandhinagar (13/03/08); Primary School,
Malanpur, Patdi, Surendranagar (15/03/08); General Hospital, Gandhinagar (15/03/08 to
17/03/08); Chaklasi, Nadiad, Kheda (24/03/08 to 26/03/08); Shree Karunasagar Seva Samaj
Trust, Satkaival Ashram, Vasad, Anand (26/03/08); Fagvel, Kathalal, Kheda (29/03/08 to
31/03/08)
(P) COMMUNITY LECTURES BY STAFF
At Cancer Detection Camps, the staff of GCRI also delivers Public Lectures. They are
often invited by the Social Organisations also. At COC, Vasna, the visiting school/college
students, Mahila Mandals and other Social and Cultural Organisations arranged meetings where
the faculty of the Institute address and interact with people.
61
No. Name of Place Topic Date
Speaker
1 Kalpana Dave CME on Oncology, Management of gynaec July 29,
Mahesana cancers 2007
2 Obstetrics and Gynaec Management of GTN August
Society, Ahmedabad 2007
3 Ava Desai Obstetrics and Gynaec Hereditary ovarian cancer April 29,
Society, Bhavnagar 2007
4 Practical Obstetrics & Surgical technique of November
Gynaecological Congress, Wertheim’s hysterectomy 2007
Chennai
5 Symposium on Ovarian tumours in young August 12,
Gynaecological Cancer, women 2007
Obstetrics and Gynaec
Society, Rajkot
6 FOCUS Post-Graduate Cervical cancer & ovarian August 21-
Teaching Programme, cancer 22, 2007
Thrissur
7 West Zone YUVA FOGSI Post menopausal bleeding October 13-
Conference, Ahmedabad 14, 2007
8 Gujarat Sarvar Mandal, Menopause – The change October 6,
AMA Hall, Ahmedabad of life 2007
9 AOGS PG Training Cervical cancer August
Programme, Ahmedabad 2007
10 Obstetrics and Gynaec Early diagnosis of gynaec December
Society, Bharuch malignancies 16, 2007
11 PG Lecture at Pulse Gestational trophoblastic December
Hospital, Ahmedabad disease 22, 2007
12 Regional Provident Fund Women’s Health March 7,
Office, Ahmedabad 2008
13 Meeta Mankad AOGS, Ahmedabad Lecture on recent December
advances in detection of 2007
cervical cancers
14 Anjana Chauhan CME jointly organised with HPV vaccine in prevention April 29,
SOGOG, Bhavnager of cancer cervix 2007
15 Yuva FOGSI West Zone HPV infection of cervix October 13,
Conference, Ahmedabad 2007
16 Ruchi Arora Kadvasan Camp Pap Smear January 26,
2007
17 Kamlesh Mishra Camp at Mahavir VILI and Pap smear for February
International Society, detection of preinvasive 2008
Dahod, Gujarat and early cancer cervix
18 Army Hospital, Ahmedabad lesions March 12,
2008
62
(Q) PATIENT CARE EVALUATION COMMITTEE
The first meeting of Patient Care Evaluation Committee was held on July 25, 2003. Dr.
Pankaj Shah, Dr. NL Patel, Shri Prashant Kinarivala, Dr. Rajendra Dave, Dr. Kirti Patel, Dr.
Shilin Shukla, Dr. BG Pandya, Mr. NT Chavda, Smt. Jayaben Panchal and Smt. Ashaben
Desai are the permanent members of the committee. The committee randomly called the patients
from different wards and asked them about their experiences regarding hospital. Patient’s
suggestions are followed. A questioner has been made with a mention of duration of admission in
the hospital, experiences on admission and during their stay in the hospital, information received
about the disease, suggestions regarding treatment expense, opinion about the behaviour of
Doctors, Nurses and other staff members and other important remarks of the patients.
Date of Meeting Chief Guest
April 21, 2007 Office bearers of GCRI and GCS
May 5, 2007 Office bearers of GCRI
May 19, 2007 Office bearers of GCRI and GCS
June 30, 2007 Dr. Girish Parmar, Dean Dental College; Office bearers of GCRI
and GCS
August 4, 2007 Office bearers of GCRI
August 18, 2007 Office bearers of GCRI and GCS
September 1, 2007 Dr. Ramesh Mehta, Invited Guest; and Office bearers of GCRI
September 15, 2007 Office bearers of GCRI
September 22, 2007 Office bearers of GCRI
November 3, 2007 Office bearers of GCRI
December 1, 2007 Dr. Chirag Desai and Office bearers of GCRI
December 15, 2007 Office bearers of GCRI
December 29, 2007 Smt. Sadhanaben Bhatt, Director, Akashvani;
Shri Tarunbhai Shukla, Akashvani; and Office bearers of GCRI
January 19, 2008 Office bearers of GCRI
February 9, 2008 Shri Ajay Upadhyay and Office bearers of GCRI
February 23, 2008 Smt. Amitaben Shah, Patient’s relative; Shri Prafulbhai Patel,
Donor; and Office bearers of GCRI and GCS
March 29, 2008 Office bearers of GCRI
63
VI. GCRI RESEARCH ACTIVITIES
APRIL 2007 – MARCH 2008
RESEARCH PROJECTS - SUMMARY TABLE
DEPARTMENT/ DIVISION PROJECTS PUBLICATIONS PRESENTATIONS
Pathology 01 00 02
Blood Bank 00 00 01
Microbiology 01 00 01
Radiodiagnosis 00 02 01
Surgical Oncology 02 05 02
Gynaecological Oncology 02 00 12
Medical Oncology 00 04 10
Anaesthesiology 00 01 06
Radiotherapy – Medical Physics 00 03 08
Cell Biology 07 01 04
Molecular Endocrinology I 06 00 03
Molecular Endocrinology II 05 00 07
Receptor & Growth Factor Lab 05 01 05
Biochemistry Research 07 06 12
Immunohistochemistry 07 00 11
Medicinal Chemistry & 03 00 01
Pharmacogenomics
Community Oncology 05 00 00
Total 51 23 86
Funding Agencies:
Gujarat Cancer Society : 24
Department of Biotechnology (DBT) : 01
Department of Atomic Energy (DAE) : 01
Government of India : 01
Indian Council of Medical Research (ICMR) – IndoGerman Collaboration : 01
Indian Council of Medical Research (ICMR) : 03
Government of Gujarat : 01
Gujarat State Biotechnology Mission (GSBTM) : 02
Directorate of Medical Education & Research (DMER), Gujarat State : 16
Gujarat Council of Science and Technology (GCST) : 01
CLINICAL TRIALS
sponsored by Pharmaceutical Companies
Department Clinical Trials
Medical Oncology 19
64
RESEARCH PROJECTS
APRIL 2007 – MARCH 2008
Pathology: identify patients who are at risk of developing
1. Project Title: Angiogenesis, p53, ER, PR local recurrence and aggressive adjuvant
and bcl-2 expression as prognostic treatment can be instituted to decrease the
indicator in endometrial carcinoma: 100 incidence of locoregional relapse in these
patients. Number of patients (100); Number of
cases study. PI: Dr. Kaushambi Shukla;
Tests (300); Name of Parameters: MMP9,
CO-PI: Dr. Kirti Patel, Dr. Manoj Shah, Dr.
elF4E and p53; Status: On-going.
Priti Trivedi, Dr. Biren Parikh, Dr. Birwa
Shah, Dr. Lopa Modi; Funding: The Gujarat 4. Project Title: Assessment of molecular
Cancer Society; Aim: The purpose of the study predictors of response to neoadjuvant
was to determine molecular markers in chemotherapy in locally advanced head
and neck squamous cell carcinoma
endometrial carcinoma to identify patients at
patients. PI: Dr. Kiran Kothari, Dr. Modit
high recurrence or metastasis. Number of
Agarwal; CO-PI: Dr. Hemangini Vora, Dr.
Patients (100); Number of Tests (450); Name
Manoj Shah, Dr. Shilin Shukla, Dr. Mahesh
of Parameters: p53, ER, PR and bcl-2; Patel; Funding: The Directorate of Medical
Inference: Hormone receptor negativity, p53 Education & Research; Aim: To identify
expression and Bcl2 expression as well as molecular markers which will help us to identify
high microvessel count identifies aggressive patients who are likely to respond to
phenotype of endometrioid carcinoma. Status: chemotherapy and these patient should be
th
Completed; Presentations (2): 1) 25 IACR, offered upfront chemotherapy so that organ
February 2005, Navi Mumbai; 2) 27th IACR, preservation can be achieved. Number of
February 2008, Ahmedabad. patients (100); Number of Tests (300); Name
Microbiology: of Parameters: GST-p, p53, bcl-2, bax and
EGFR; Status: On-going.
2. Project Title: Detection of high and low
risk human papilloma virus (HPV) subtypes Gynaecological Oncology:
prevalent in cancerous and non-cancerous 5. Project Title: Concurrent radiotherapy &
lesions of the uterine cervix in Indian chemotherapy (Cisplatin) vs radiotherapy
women. PI: Dr. Parijath Goswami; CO-PI: for locally advanced cancer cervix. PI:
Dr. Kalpana Dave, Dr. Ava Desai; Funding: Dr. Pariseema Dave; CO-PI: Dr. Anjana
The Gujarat Cancer Society; Aim: Study was Chauhan, Dr. Kalpana Dave, Dr. Ava Desai,
conducted to detect the HPV subtypes in Dr. Mita Mankad, Dr. Shilpa Patel, Dr. Ronak
clinically diagnosed cervical lesions using Bhansali, Dr. Rakesh Vyas, Dr. Jayprakash
multiplex PCR. Number of Patients (263); Neema, Dr. Asha Anand, Dr. Apurva Patel,
Number of Tests (263); Name of Parameters: Dr. Harsha Panchal; Funding: The Gujarat
multiplex PCR and histopathology; Inference: Cancer Society; Aim: To analyze the effects of
HPV 16 is more than 18, though other types of chemoradiotherapy on: (i) overall and
HPV like 45,31,35,39,52,59,33 were also progression free survival, (ii) local and distant
detected in the cervical lesions. Status: On- control, and (iii) side effect profile in patients
going; Presentations (2): 1) Update for with locally advanced cancer cervix. Number of
Paramedical Techniques in Pathology, Patients: (Arm A: 55, Arm B: 53); Number of
October 2006, Ahmedabad; 2) AGOICON Tests: (1080); Name of Parameters: biopsy of
2006, November 2006, New Delhi. the cervix, radiological examination - chest X-
Surgical Oncology: ray, USG abdomen-pelvis, blood tests-CBC,
LFT, RFT, HIV, HBsAg, urine-routine and
3. Project Title: Molecular assessment of
surgical margins in head and neck microscopy, clinical and radiological evidence
squamous cell carcinoma patients. PI: Dr. of disease, treatment related toxicity; Status:
Kiran Kothari, Dr. Hemangini Vora; CO-PI: Completed; Publication/Presentation:-
Dr. Manoj Shah, Dr. Modit Agarwal, Dr. 6. Project Title: Role of neoadjuvant
Shilin Shukla; Funding: The Directorate of chemotherapy in advanced epithelial
Medical Education & Research; Aim: To ovarian cancer. PI: Dr. Shilpa Patel; CO-PI:
identify molecular markers which will help us to Dr. Ronak Bhansali, Dr. Kalpana Dave, Dr.
65
Ava Desai, Dr. Mita Mankad, Dr. Pariseema BCR-ABL dual color dual fusion/ 9q34/ or other
Dave, Dr. Anjana Chauhan, Dr. Bharat relevant probes (Vysis, USA) as per the case;
Parikh, Dr. Apurva Patel, Dr. Harsha Status: On-going; Publication (1): 1) Journal of
Panchal, Dr. Shreedevi Patel; Funding: The Association of Genetic Technologists, 32:162-
Gujarat Cancer Society; Aim: To evaluate 167, 2006; Title: Atypical D-FISH patterns of
neoadjuvant chemotherapy in advanced BCR/ABL gene rearrangements in chronic
epithelial ovarian cancer with respect to myeloid leukemia patients. Abstract: The
response rate, the rate of optimal debulking, Philadelphia (Ph) chromosome, a hallmark
surgical morbidity and quality of life. Number of chromosomal anomaly observed in 95 percent
Patients: (30); Number of Tests: (360); Name of chronic myeloid leukemia (CML) cases, is
of Parameters: CBC, BT, CT, PT, RFT, LFT, known to involve the Abelson (ABL) proto-
HBSAg, HIV, CA125, X-ray Chest, USG, CT oncogene on chromosome 9 and the
Scan; response to chemotherapy and toxicity, breakpoint cluster region (BCR) gene on
rate of resectibility, surgical morbidity, quality chromosome 22, producing BCR/ABL mRNA
of life; Status: Completed; encoding an abnormal tyrosine kinase protein.
Publication/Presentation:- In the process of generating BCR-ABL fusion,
Cell Biology: the deletion of residual BCR or ABL occurs in
15-30 percent of CML patients. In addition,
7. Project Title: Characterization of
some rearrangements are complex, and do not
chromosome rearrangements of malignant
yield the ABL/BCR fusion due to the
effusions with multiplex-FISH. PI: Dr. Sonal
involvement of a third chromosome in the
Bakshi; CO-PI: Dr. Shilin Shukla, Dr. Pankaj
rearrangement. The possible role of these
Shah; Funding: The Gujarat State
deletions and complex rearrangements in
Biotechnology Mission; Aim: To study
disease outcome is an on-going topic of
malignant effusion cells for Karyotype analysis
research. We report our results of cytogenetic
aided with FISH and m-FISH in patients with
analysis with GTG banding and fluorescence
various malignancies having ascitic or pleural
in situ hybridization using dual color dual
effusion. Number of Patients: (30); Number of
fusion probe (D-FISH) from Vysis Inc, USA in
Tests: (60); Name of Parameters: GTG
169 (109 males and 60 females) CML patients
banded karyotyping; Multiplex-FISH
registered at The Gujarat Cancer & Research
karyotyping; Status: On-going.
Institute (GC & RI) from April 2004 to
8. Project Title: A conventional and December 2005. GTG banding was carried out
molecular cytogenetic analysis of in 123 cases having analyzable metaphases.
philadelphia chromosome and variants in Of these 123 cases, D-FISH revealed atypical
chronic myeloid leukemia patients. PI: Dr. signal patterns in 57 patients (46%), and 12
Beena Patel; CO-PI: Ms. Manisha cases revealed additional complex
Brahmbhatt, Dr. Sonal Bakshi, Dr. Shilin translocations indicative of disease
Shukla, Dr. Pankaj Shah; Funding: The progression. Out of 57 cases with atypical
Gujarat Council of Science and Technology; FISH patterns, 22 included metaphase FISH
Aim: To study the bone marrow and/or blood results, and the rest had only interphase FISH
lymphocytes for karyotype analysis aided with performed. In addition to the hallmark
FISH in CML patients. The status of the Philadelphia chromosome, other chromosomal
additional chromosomal anomaly other than aberrations in CML revealed heterogeneity of
the known philadelphia chromosome will be molecular events. Pooling of more data may
correlated clinically in terms of response to lead to identification of new CML sub-groups
therapy, duration of chronic phase, and overall and hence help in the analysis of clinical trials.
survival. Number of Patients: (150); Number of Patients enrolled in our prospective study of
Tests: (150 at diagnosis and during follow-up); prognostic significance will be followed up for
Name of Parameters: (i) Philadelphia disease free and overall survival in correlation
chromosome and other variants by with ABL-BCR deletion status. Presentations
conventional cytogenetics, (ii) BCR-ABL th
(2): 1) 27 IACR, February 2008, Ahmedabad;
fusion by the FISH and, (iii) Deletion status of 2) Human Health Care: Redefined 2008,
der(9)t(9;22) by FISH using LSI BCR/ABL-ES/ March 2008, Ahmedabad.
66
9. Project Title: Acute lymphocytic Number of Patients: (75); Number of Tests: (75
leukemia: A cytogenetic exploration. PI: Dr. at diagnosis and during follow-up); Name of
Sonal Bakshi; CO-PI: Ms. Manisha Parameters: Karyotyping and FISH using
Brahmbhatt, Dr. Bharat Parikh, Dr. Kirti commercially available and custom made
Patel, Dr. Shilin Shukla, Dr. Pankaj Shah; probes; Status: On-going; Presentation (1): 1)
th
Funding: The Gujarat Cancer Society; Aim: To 27 IACR, February 2008, Ahmedabad.
record cytogenetic anomalies in ALL patients 12. Project Title: Cloning of novel and rare
at diagnosis, and during treatment; to analyse chromosomal translocations in acute
retrospectively the effect of different variables myeloid and lymphoblastic leukemia (AML
like type of anomaly, treatment given etc.; to and ALL). PI: Dr. Sonal Bakshi, Dr. Stefan
characterize complex chromosomal anomalies Bohlander; Funding: ICMR, Indo-German
with advanced cytogenetic approaches like collaboration; Aim: To characterize rare
FISH; and to establish a consortium of BAC balanced chromosomal translocations and
FISH probes for routine use for GCRI patients. other rearrangements in acute myeloid and
Number of Patients: (75); Number of Tests: (75 acute lymphoblastic leukemias. Number of
at diagnosis and during follow-up); Name of Patients: (15 to 20); Number of Tests: (60 to
Parameters: Karyotyping and FISH using 80); Name of Parameters: GTG banded
commercially available and custom-made karyotyping, FISH, M-FISH, and BAC-FISH;
probes; Status: On-going. Status: On-going.
10. Project Title: Acute myeloid leukemia: A 13. Project Title: Detection of BCR-ABL
cytogenetic exploration. PI: Dr. Sonal gene by polymerase chain reaction in
Bakshi; CO-PI: Ms. Manisha Brahmbhatt, chronic myeloid leukemia (CML) and
Dr. Bharat Parikh, Dr. Kirti Patel, Dr. Shilin differential diagnosis of lymphoid
Shukla, Dr. Pankaj Shah; Funding: The leukaemia. PI: Dr. Beena Patel; CO-PI: Dr.
Gujarat Cancer Society; Aim: To record Sonal Bakshi, Dr. Shilin Shukla, Dr. Pankaj
cytogenetic anomalies in AML patients at Shah; Funding: Directorate of Medical
diagnosis, and during treatment; to analyse Education and Research; Aim: The PCR
retrospectively the effect of different variables based detection of p210 and p190 sequences
like type of anomaly, treatment given etc.; to are the only test for the differentiation of acute
characterize complex chromosomal anomalies lymphocytic leukemia (ALL) from chronic
with advanced cytogenetic approaches like myeloid leukemia (CML) as well as detection
FISH; to establish a consortium of BAC FISH of minimal residual disease and monitoring
probes for routine use for GCRI patients. CML patients following transplantation. The
Number of Patients: (75); Number of Tests: (75 sensitivity of PCR allows detection of as few as
at diagnosis and during follow-up); Name of 1-10 bcr-abl positive cells in million cells, which
Parameters: Karyotyping and FISH using makes PCR methods ideal for early detection
commercially available and custom-made of relapse. Number of Patients (55); Number of
probes; Status: On-going; Presentation (1): 1) Tests (75); Name of Parameters: p210 and
th
27 IACR, February 2008, Ahmedabad. p190 sequence; Inference: The first year report
11. Project Title: Chronic myeloid leukemia: consists of the standardization of the PCR
A cytogenetic exploration. PI: Dr. Sonal reaction using positive cell line k562 (for p210)
Bakshi; CO-PI: Ms. Manisha Brahmbhatt, and SupB15 (for p190). cDNA samples from
Dr. Bharat Parikh, Dr. Kirti Patel, Dr. Shilin these cell lines were received as generous gift
Shukla, Dr. Pankaj Shah; Funding: The from Dr. Hany Ariffin (University of Malaya,
Gujarat Cancer Society; Aim: To record Paediatric Hematology Oncology Unit,
cytogenetic anomalies in CML patients at Malaysia). cDNA from SupB15 showed 298 bp
diagnosis, and during treatment; to analyse fragment using specific primers for p190
retrospectively the effect of different variables sequence. While cDNA of K562 cell line is
like type of anomaly, treatment given etc.; to under process for the identification of p210
characterize complex chromosomal anomalies sequence. Blood samples from 6 CML and 3
with advanced cytogenetic approaches like ALL patients were drown. WBC were
FISH; and to establish a consortium of BAC separated from the blood samples and RNA
FISH probes for routine use for GCRI patients.
67
was extracted from these samples. Status: On- Dr. Premal Thakor, Dr. Shilin Shukla, Dr.
going. Manas Mayank, Dr. Pankaj Shah; Funding:
Molecular Endocrinology I: The Gujarat Cancer Society; Aim: To evaluate
circulating levels of Thyroglobulin, anti-
14. Project Title: Immunohistochemical
Thyroglobulin Ab, TPO Ab, and TSH-R in
studies in thyroid malignancies. PI: Dr.
patients with thyroid abnormality and thyroid
Girish Patel; CO-PI: Dr. Premal Thakor, Dr.
cancer. Number of Patients (200); Number of
Manoj Shah, Dr. Shilin Shukla; Funding: The
Tests: (1000; pretreatment and follow-up blood
Gujarat Cancer Society; Aim: To study the
samples); Name of Parameters: Thyroglobulin,
expression of Thyroglobulin, TPO, EMA, Leu7
Anti-thyroglobulin Ab, TPO Ab and TSH-R;
Ag in thyroid carcinoma patients. Number of
Status: On-going.
Patients (60); Number of Tests (240); Name of
Parameters: Thyroglobulin, TPO, EMA, Leu7 18. Project Title: Understanding
Ag; Status: On-going. involvement of several molecules in thyroid
tumorigenesis. PI: Dr. Girish Patel; CO-PI:
15. Project Title: Tumor markers in
Dr. Sunil Trivedi, Dr. Premal Thakor, Dr.
pancreatic carcinoma. PI: Dr. Girish Patel;
Shilin Shukla, Dr. Pankaj Shah; Funding:
CO-PI: Dr. Yatin Patel, Dr. Rajan Tankshali;
Directorate of Medical Education and
Funding: The Gujarat Cancer Society; Aim: To
Research; Aim: To determine TNF, Interleukin,
study usefulness of CA 19-9, CEA and CA
Interferone, TGF & TSH-R in suspected cases
72.4 in pancreatic carcinoma patients. Number
of thyroid malignancies. Number of Patients
of Patients (100); Number of Tests: (600; blood
(200); Number of Tests: (1000; pretreatment
and pancreatic juice samples of pancreatic
blood and follow-up samples); Name of
cancer patients); Name of Parameters: CA 19-
Parameters: TNF, Interleukin, Interferone,
9, CEA, CA 72-4; Inference: CA19-9 in
TGF, TSH-R; Status: On-going.
pancreatic juice was significantly higher in
patients with pancreatic cancer. No correlation 19. Project Title: Clinical utility of p27 in
with CA19-9 and CEA in pancreatic juice and colorectal carcinoma. PI: Dr. Girish Patel;
serum were found. Rise in the levels of both CO-PI: Dr. Sunil Trivedi, Dr. Rajendra Dave,
CEA and CA 19-9 were correlated with clinical Dr. Shilin Shukla, Dr. Pankaj Shah; Funding:
disease status. Status: On-going; Presentation Directorate of Medical Education and
th
(1): 1) 27 IACR, February 2008, Ahmedabad. Research; Aim: To evaluate the level of p27 in
malignant tissues of colorectal carcinoma
16. Project Title: Clinical utility of p27 in
patients by enzyme immunoassay (EIA)
breast carcinoma. PI: Dr. Girish Patel; CO-
technique. Number of Patients (200); Number
PI: Dr. Sunil Trivedi, Dr. Shashank Pandya,
of Tests: (400; tumor and normal adjacent
Dr. Shilin Shukla, Dr. Manoj Shah; Funding:
tissue samples); Name of Parameters: Total
Directorate of Medical Education and
protein and p27 protein; Status: On-going.
Research; Aim: To evaluate the level of p27 in
pre-therapeutic primary breast cancer patients Molecular Endocrinology II:
and in patients with secondaries in bones. 20. Project Title: Clinical significance of
Number of Patients (40); Number of Tests Stat1 and Stat3 expression in breast
(160; tumor and adjacent normal tissue cancer. PI: Dr. Neelam Shah; CO-PI: Dr.
samples); Name of Parameters: p27 protein; Trupti Trivedi, Dr. Jignesh Goswami, Dr.
Inference: The present study conclusively Shilin Shukla, Dr. Pankaj Shah; Funding:
supports implication of p27 expression in the Directorate of Medical Education and
prognostication of breast cancer. It signifies Research; Aim: To study one of the signals
the important role of p27 in breast essential for upregulation of cell-cycle
tumorigenesis. Status: On-going; Presentation regulatory genes. Thus, the present study
th
(1): 1) 27 IACR, February 2008, Ahmedabad. aimed to examine the protein and mRNA
17. Project Title: Immunochemical expression of Stat1 and Stat3 in primary breast
substances in thyroid disorders and tumors of patients with early and advanced
thyroid malignancies. PI: Dr. Girish Patel; breast cancer. Number of Patients: (100);
CO-PI: Dr. Sunil Trivedi, Dr. Urvi Parekh, Number of Tests: (400); Name of Parameters:
68
Stat1 and Stat3 protein and mRNA expression; (APC) and D3S1283 (hMLH1) instability;
Status: On-going. Status: On-going.
21. Project Title: Role of Stat5 and Stat6 in 24. Project Title: Expression of EGFR, c erb
oral squamous cell carcinoma. PI: Dr. B2, STAT-3, Bcl-2 and cyclin D1 in pre-
Neelam Shah; CO-PI: Dr. Trupti Trivedi, Dr. malignant and malignant lesions of the
Rajan Tankshali, Dr. Jignesh Goswami, Dr. buccal mucosa. PI: Dr. Neelam Shah; CO-
Shilin Shukla, Dr. Pankaj Shah; Funding: PI: Dr. Trupti Trivedi, Dr. Jignesh Goswami,
Directorate of Medical Education and Dr. Shakuntala Shah, Dr. Shilin Shukla, Dr.
Research; Aim: Future advances in the Pankaj Shah; Funding: The Gujarat Cancer
treatment and prognosis of OSCC rely upon a Society; Aim: Studies have shown the
better understanding of the molecular events importance of cell cycle regulatory pathways
that underlie tumor development and (Rb and p53) in oral carcinogenesis but there
progression, allowing specific targeting of the is paucity of data on the clinical relevance of
involved molecules and pathways. In this STAT-3 and EGFR (gene products of the
context, lack of data on the clinical relevance mitogenic signaling pathway and involved in up
of Stat5 and Stat6 prompted us to determine regulation of cell cycle regulatory pathway) in
their role in oral squamous cell carcinoma. oral carcinogenesis. Hence, the present study
Number of Patients: (125; 25 premalignant and aimed to evaluate the significance of EGFR, c
100 malignant); Number of Tests (250); Name erb B2, STAT-3, Bcl-2 and cyclin D1
of Parameters: Stat5 and Stat6; Status: On- expression in normal oral mucosa, and pre-
going. malignant and malignant lesions of the buccal
22. Project Title: Expression of Fas mucosa. Number of patients (122); Number of
receptor mRNA and Fas ligand mRNA in Tests (600); Name of Parameters: EGFR, c
patients with colorectal carcinoma. PI: Dr. erb B2, STAT-3, Bcl-2 and cyclin D1;
Nandita Ghosh; CO-PI: Dr. Neelam Shah, Inference: Amongst the five markers studied,
Dr. Shilin Shukla, Dr. Shakuntala Shah, Dr. cyclin D1 an important cell cycle regulatory
Rajendra Dave, Dr. Pankaj Shah; Funding: pathway protein was an independent predictor
Directorate of Medical Education and of risk for hyperplasia and early stage disease
Research; Aim: To study the expression of Fas from normal and dysplasia conditions,
and Fas ligand (FasL) mRNA by RT-PCR in respectively. On the otherhand, the significant
patients with colorectal cancer to examine its risk predicators for transition to dysplasia from
relationship with several prognostic hyperplasia and to progressive disease from
pathological features, to evaluate its early stage were STAT-3 at step 1 followed by
correlation if any with treatment response and EGFR. Thus, STAT-3 and EGFR associated
to correlate it with survival. Number of Patients with the mitogenic signalling pathway play an
(50); Number of Tests (100); Name of equally significant role in oral carcinogenesis
Parameters: Fas ligand mRNA and Fas as cyclin D1 which is an important cell cycle
receptor; Status: On-going. regulatory pathway protein. Status: Completed;
Publication (1): 1) International Journal of
23. Project Title: Role of microsatellite
Biological Markers, 22:132-143, 2007; Title:
markers in patients with adenomatous
Molecular alterations in oral carcinogenesis:
polyps and colorectal carcinoma. PI: Dr.
significant risk predictors in malignant
Nandita Ghosh; CO-PI: Dr. Neelam Shah,
transformation and tumor progression.
Dr. Shilin Shukla; Dr. Yatin Patel, Dr.
Abstract: In this study an attempt was made to
Shakuntala Shah, Dr. Jignesh Goswami, Dr.
address significance of a battery of molecular
Pankaj Shah; Funding: The Gujarat Cancer
alterations and thereby identify risk predictors
Society; Aim: To evaluate the usefulness of
in oral carcinogenesis. For this, EGFR, Stat3,
microsatellite instability status in patients with
H-ras, c-myc, p53, cyclin D1, p16, Rb, Ki-67
adenomatous polyps and colorectal cancer.
and Bcl-2 were localized
Number of patients: (25 adenomatous polyps
immunohistochemically in normal mucosa
and 50 adenocarcinoma); Number of Tests:
(N=12), hyperplasia (N=35), dysplasia (N=25),
(375); Name of Parameters: hMSH2 and
early stage carcinoma (N=65) and advanced
hMLH1 protein and BAT-26 (hMSH1), D5S346
stage carcinoma (N=70). Deregulation
69
occurred at an early stage and number of Bhubaneswar; 2) International symposium on
alterations increased with disease progression. translational Research, December
Using multivariate logistic regression analysis, 2004,Thiruvananthapuram.
the significant risk predictor for hyperplasia 26. Project Title: Insights into basic biology
from normal mucosa was Ki-67 (OR=5.75, of oral cancer. PI: Dr. Prabhudas Patel; CO-
P=0.021), for dysplasia from hyperplasia, they PI: Dr. Rakesh Rawal, Dr. Devendra Patel;
were EGFR (OR=12.96, P=0.002), Stat3 Funding: Department of Biotechnology; Aim:
(OR=17.16, P=0.0001), p16 (OR=5.50, Evaluation of (i) telomerase activation (ii)
P=0.039) and c-myc (OR=5.99, P=0.052), for evaluation of telomere length alterations and
early stage carcinoma from dysplasia, they expression of telomere repeat binding factors,
were p53 (OR=6.63, P=0.0001) and Rb TRF-1 and TRF-2 (iii) expression of
(OR=3.81, P=0.056), and with further telomerase components including hTR (RNA
progression, they were EGFR (OR=5.50, component), hTERT (catalytic subunit) and
P=0.0001), Stat3 (OR=4.49, P=0.0001), H-ras hTLP (protein component) (iv) mutation in
(OR=4.05, P=0.001) and c-myc (OR=2.99, important cell cycle regulatory genes including
P=0.015). Cyclin D1 holds a key position p53, Rb, ras and c-myc in oral scrapping
linking upstream signaling pathways to cell samples. Number of Patients: (200); Number
cycle regulation. Gene products of mitogenic of Tests: (2000); Name of Parameters:
signaling pathway play an equally significant Telomerase activation, telomerase repeat
role as cell cycle regulatory proteins in binding factors, TRF-1, TRF-2, hTERT, hTLP,
hyperplasia- dysplasia- early- advanced- p53, Rb, ras and c-myc; Status: Ongoing;
carcinoma sequence and together may provide Publication (1): 1) Biomarker Insights 2: 12–22,
a reference panel of markers for use in 2007; Title: Clinical significance of telomere
defining premalignant lesions and predicting length and associated proteins in oral cancer.
risk of malignant transformation and tumor Abstract: Telomere shortening is an important
progression. Presentations (3): 1) International event during carcinogenesis. Although studies
Symposium on Translational Research, suggest role of multiple proteins in telomere
December 2005, Trivendrum; 2) 26th IACR, length regulation, there is dearth of reports in
th
January 2007, Bhuvneshwar; 3) 27 IACR, oral cancer which is a leading malignancy in
February 2008, Ahmedabad. Asian countries especially in India. Thus the
Biochemistry Research: present study was carried out to study these
25. Project Title: Multi-parametric approach mechanisms and explore the pathways
to predict treatment outcome in patients involved in telomere - telomerase regulation
with malignant solid tumors undergoing and identify possible prognostic markers to
primary radiotherapy. PI: Dr. Prabhudas understand the biology of oral tumors for better
Patel; CO-PI: Dr. Rakesh Rawal, Dr. Shilin treatment approaches. Telomere length was
Shukla, Dr. Pankaj Shah; Funding: determined by southern hybridisation method,
Department of Atomic Energy; Aim: To assess telomeric repeat binding factor (TRF) 1 and 2
the clinical usefulness of molecular and expression was detected by western blot
biochemical markers in patients with head and method and telomerase activation by telomeric
neck cancer and cervix cancer undergoing repeat amplifi cation protocol. Statistical
radiotheraphy as primary anti cancer analysis was done using SPSS (Version 10)
treatment. Number of Patients: (200); Number software. Significant shortening of telomeres
of Tests: (2800); Name of Parameters: was seen in the tumor tissues as compared to
Glutathione S-transerase, Glutathion normal tissues. Poor prognosis was observed
Reductase, Glutathione Peroxidase, in the patients with higher telomere length in
Superoxide Dismutase, Catalase, Lipid malignant tissue, higher tumor to normal
Peroxidation, Total and Lipid bound Sialic acid, telomere length ratio (T/N TRF LR).
Seromucoid Fraction, p53, p21, NFK-B, DNA Expression of TRF-2 but not TRF-1 protein
damage and repair by comet assay (Single was significantly higher in the malignant
Cell Gel electrphoresis); Status: On-going; tissues. We also observed telomerase
th
Presentations (2): 1) 26 IACR, January 2007, activation in 75 malignant tissues. Our results
70
reveal significant clinical usefulness of 30. Project Title: E-cadherin expression as
telomere length, T/N TRF LR and telomerase marker for invasion and metastasis in
activation in the prognosis of oral cancer breast cancer. PI: Dr. Franky Shah; CO-PI:
patients. TRF-2 overexpression in malignant Dr. Prabhudas Patel, Dr. Shilin Shukla, Dr.
tissues appears to play an important role in Pankaj Shah; Funding: The Directorate of
telomere length shortening in oral cancer. Medical Education and Research; Aim: Breast
Presentations (2): 1) 26th IACR, January 2007, cancer is a leading female malignancy and
Bhubaneswar; 2) 24th IACR, February 2005, invasion and metastasis is the major problem
Noida. in these patients. The expression of E-
27. Project Title: Study of GST-T1, GST-M1 cadherin, which is directly related to cell to cell
and CYP1A1 polymorphisms in oral cancer. cohesion, is inversely correlated with tumor
PI: Dr. Prabhudas Patel; CO-PI: Dr. Shilin progression and metastasis. Therefore, this
Shukla, Dr. Pankaj Shah; Funding: The project work is proposed to study E-cadherin in
Directorate of Medical Education & Research; breast cancer patients, which may be
Aim: Analysis of the polymerphisms in GST significantly useful in prognostication and early
T1, GST-M1 and CYP1A1 genes in patients detection of metastasis in breast cancer
with oral cancer and patients with oral patients. Number of Patients: (150); Number of
precancers. Number of Patients: (150); Tests: (150); Name of Parameters: E-cadherin;
Number of Tests: (450); Name of Parameters: Status: On-going.
GST-M1, GST-T1 and CYP1A1 genotype; 31. Project Title: Role of Nitric Oxide and its
Status: On-going; Presentation (1): 1) National associated biomarkers in oral cancer. PI:
Symposium on Apoptosis and Cancer, Dr. Jayendra Patel; CO-PI: Dr. Prabhudas
December 2007, Vadodara. Patel, Dr. Shilin Shukla, Dr. Pankaj Shah;
28. Project Title: Evaluation of NF-kB Funding: The Directorate of Medical Education
activation pathway in oral cancer. PI: Dr. and Research; Aim: Oral cancer is a leading
Prabhudas Patel; CO-PI: Dr. Beena Patel, malignancy in India. It is a multi-step process
Dr. Hemant Shukla; Funding: The Gujarat progressing through various stages including
Cancer Society; Aim: (i) To study role of NF-Kb hyperplasia, dysplasia and carcinoma in situ.
activation pathways including activation of NF- Free radicals and antioxidant enzymes play an
KB dissociation of NF-KB inhibitory proteins, important role in development of oral cancer.
IKBs, up regulation of interlukin-8 (IL-8) and Therefore, aims of project are to (i) evaluate
activation of matrix metalloproteins, MMP-2 plasma nitrite+nitrate (NO2+NO3) in healthy
and MMP-9 (ii) to study clinical usefulness of individuals without habit (NHT), healthy
the status of the NF-KB pathways in early individuals with tobacco habits (WHT) and oral
diagnosis and management of oral cancer cancer patients, (ii) study of expression of
patients. Number of Patients: (150), Number of inducible nitric oxide (iNOS) in oral cancer
Tests: (450); Name of Parameters: NF-kB, patients, (iii) estimate antioxidant enzymes in
IKBs, IL-8, MMP-2, MMP-9; Status: On-going; NHT, WHT, and oral cancer patients, (iv) study
Presentation (1): 1) International Symposium association of plasma NO2+NO3 with
on Translational Research, December 2004, antioxidant enzymes. Number of Patients:
Thiruvananthapuram. (150); Number of Tests: (600); Name of
Parameters: NO2+NO3, Superoxide
29. Project Title: Study of molecular
dismutase, catalase, Inducible Nitric oxide;
mechanism in head and neck cancer. PI:
Status: On-going.
Dr. Prabhudas Patel; CO-PI: Dr. Shilin
Shukla, Dr. Pankaj Shah, Dr. Shakuntala Receptor and Growth Factor Lab:
Shah, Dr. Rakesh Rawal; Funding: The 32. Project Title: Progesterone receptor
Gujarat Cancer Society; Aim: Study of isoforms in breast cancer. PI: Dr. Sunil
differential protein expression profiles between Trivedi; CO-PI: Dr. Manoj Shah; Funding:
tumor and adjacent normal tissues from head The Gujarat Cancer Society; Aim: (i) To detect
and neck cancer patients. Number of Patients: progesterone receptor (PR) in human breast
(150); Number of Tests: (150); Name of tumors, (ii) To estimate the progesterone
Parameters: Protein Profile; Status: On-going. receptor (PR) protein isoforms in breast tumor
tissues, malignant lymph nodes and
71
macroscopically normal breast tissue in was seen in ~90% tumors. (v) TBRI was
synchronous tissues (obtained at the same highest in positive LN and lowest in normal
surgery), (iii) To correlate PR protein isoforms tissues. Further, TβRI expression was reduced
to established prognosticators (PR DCC levels; to half in 30% early and 40% advanced
TNM stage; node positivity; various histologic tumors. Amongst the tumors with TβRI
parameters [histologic type, histologic grade, expression, the magnitude of rise was higher
vascular permeation, lymphatic permeation, for advanced (1.49 fold) as compared to early
lymphocytic infiltration]), (iv) To evaluate these tumors (0.80 fold). (vi) TβRII was highest in
parameters for prognostication in a short normal tissues than tumors. Majority of tumors
follow-up of 2 years (and compute overall- and exhibited reduced TβRII expression. (vii)
relapse – free survival). Number of Patients: TβRIII was lowest in LNs than tumors and
(100); Number of Tests: (250); Name of normal. TβRIII expression was reduced in 48%
Parameters: Progesterone receptor isoforms, early- and 88% advanced primaries; extent of
PR – DCC; Inference: PR isoforms were expression was higher (5.02 fold) in advanced
detectable in around 40% of primary tumors, tumors with increased expression as
malignant lymph nodes and around 20 compared to only 1.83 fold for early tumors.
macroscopically normal tissues. Status: On- Status: On-going; Presentation (1): 1) 27
th
going. IACR, February 2008, Ahmedabad.
33. Project Title: Receptors for 34. Project Title: Study of estrogen receptor
transforming growth factor β and their system in human breast cancer. PI: Dr.
coactivators in breast carcinoma. PI: Dr. Sunil Trivedi; CO-PI: Dr. Shilin Shukla;
Sunil Trivedi; CO-PI: Dr. Manoj Shah; Funding: Gujarat State Biotechnology Mission;
Funding: The Gujarat Cancer Society; Aim: (i) Aim: (i) To evaluate co-expression of ER α and
Estimation of TGFβ (1,2,3) RNA levels in ER β at RNA levels in the prognostication of
breast carcinoma tissues, (ii) To correlate operable human breast cancers, (ii) To
TGFβ RNA levels to clinico-pathologic correlate these levels to clinicopathologic
variables in breast cancers, (iii) To estimate prognosticators; Number of Patients: (100);
levels of TβR (I, II, III) levels (Protein, RNA) Number of Tests: (200); Name of Parameters:
and correlate them with other prognosticators (i) m RNA ERα, (ii) mRNA ER β. Inference: (i)
in breast cancers, (iv) Correlation of all these we have been able to detect ERα and ER β
likely prognostic variables to other known mRNA in primary tumors, malignant LN and
histologic variables in breast cancers in a adjacent normal tissues, (ii) Incidence of ER β
follow-up study of 2 years. Number of Patients: RNA expression was significantly lesser than
(200); Number of Tests: (600); Name of ERα. Their relationship with other
Parameters: mRNA levels of (i) TGF β-1, (ii) prognosticators is being analyzed. Status: On-
TGF β-2, (ii) TGF β-3, (iv) TβR-I, (v) TβR-II, (vi) going.
TβR-III, (vii) GAPDH as house keeping gene; 35. Project Title: Expression of co-activator
Inference: The transcript levels exhibited a SMAD-4 in human breast carcinoma. PI: Dr.
unique pattern in each group. (i) Expression of Sunil Trivedi; CO-PI: Heena Dave; Funding:
GAPDH was maximum as compared to all set Directorate of Medical Education and
of genes and all tissues; (ii) Tumor TGF-β1 Research; Aim: (i) To determine expression of
was higher than adjacent normal tissues and common mediator SMAD-4 in breast
lower than malignant LN. Further, TGF-β1 carcinoma, (ii) To correlate SMAD-4
expression was less (50%) than adjacent expression profiles with clinico-pathological
normal tissues in 80% early tumors while in prognosticators, (iii) To evaluate the
20%, it was 2.5 fold higher. (iii) Tumor TGF-β2 usefulness of SMAD-4 estimation in predicting
was highest than both (positive LN and normal treatment response. Number of Patients:
tissue). Further, TGF-β2, showed an increased (150); Number of Tests: (150); Name of
expression (1.95 fold) in 40% early tumors and Parameters: m RNA SMAD-4; Inference: (i) we
(4.29 fold) in advanced tumors. (iv) A similar have been able to detect SMAD-4 mRNA in
expression of TGF-β3 was seen in all sample primary tumors, malignant LN and adjacent
types. Further, reduced TGF-β3 expression normal tissues, (ii) Half of the tumors showed
72
~61% reduction of SMAD-4 RNA as compared leukemogenesis. The study aimed to
to the synchronous normal tissues, (iii) determine role of FLT3 in AML. Number of
Similarly, synchronous malignant lymph nodes Patients (100); Number of Tests (375); Name
exhibited a reduction in SMAD-4 RNA by of Parameters: FLT3 mutation and protein;
th
~64%. Their relationship with other Status: On-going; Presentation (1): 1) 27
prognosticators is being analyzed. Status: On- IACR, February 2008, Ahmedabad.
going. 39. Project Title: A study of apoptosis-
36. Project Title: Estimation of insulin like related proetin expression in minimal
growth factors in human cervical residual disease in acute myeloid leukemia
carcinoma. PI: Dr. Sunil Trivedi; CO-PI: Dr. by flow cytometry. PI: Dr. Hemangini Vora,
Rakesh Vyas, Ms. Heena Dave; Funding: Dr. Shilin Shukla; CO-PI: Ms. Nilima Desai,
Directorate of Medical Education and Dr. Sonia Parikh, Dr. Shailesh Talati, Dr.
Research; Aim: (i) To estimate the Insulin like Manoj Shah, Dr. Swapan Desai, Dr. Pankaj
Growth Factors (-I, -II) and their binding protein Shah; Funding: Gujarat Cancer Society; Aim:
(IGFBP-3) in human cervical carcinoma, (ii) To In acute myeloid leukemia (AML), the complete
correlate their levels with clinico-pathological remission rate has been reported in 70-80%
prognosticators, (iii) To assess the utility of patients, however; approximately 60-70% of
IGF-I, IGF-II and IGFBP-3 in predicting the patients will eventually relapse because of
treatment response and survival. Number of the presence of residual leukemia cells.
Patients: (100); Number of Tests: (300); Name Measuring apoptosis parameters in MRD cells
of Parameters: (i) IGF-I, IGF-II, IGFBP-3; will help to unravel the importance of apoptosis
Inference: We have analyzed these molecules resistance in AML. Therefore, the study aimed
from 42 patients before start of any treatment to determine apoptosis related proteins to
(Pre-therapeutic values) till date. (i) The detect MRD in AML by Flow Cytometry.
median IGF-I, IGF-II and IGFBP-3 were 144 Number of Patients (50); Number of Tests
ng/ml, 994 ng/ml and 3187.50 ng/ml serum (200); Name of Parameters: apoptotic
respectively. Their relationship with other markers; Status: On-going.
prognosticators is being analyzed. Status: On- 40. Project Title: Detection of truncated
going. Her-2 neu protein in patients with breast
Immunohistochemistry: cancer. PI: Dr. Hemangini Vora; Dr. Shilin
37. Project Title: Study of Her-2 neu Shukla; CO-PI: Dr. Harsha Panchal, Dr.
expression in breast cancer and its Manoj Shah, Dr. Pankaj Shah; Funding:
correlation with ER, PR, clinicopathological Directorate of Medical Education and
parameters and treatment. PI: Dr. Shilin Research; Aim: In earlier study on Her-2 neu
Shukla, Dr. Hemangini Vora; CO-PI: Dr. mRNA in breast cancer, splice variant of Her-2
Manoj Shah, Dr. Harsha Panchal, Ms. Nilima neu mRNA was detected which correlated with
Desai, Dr. Pankaj Shah; Funding: The early tumor recurrence. The hypothesis made
Gujarat Cancer Society; Aim: To study role of that is protein translated by variant HER-2 neu
Her-2 neu signalling in breast cancer. Number mRNA truncated? The study aimed to detect
of Patients (100); Number of Tests (300); the role of truncated HER-2 neu protein in
Name of Parameters: Her-2 neu mutation and breast cancer. Number of Patients (60);
protein; Status: On-going; Presentation (1): 1) Number of Tests (75); Name of Parameters:
th
27 IACR, February 2008, Ahmedabad. Her-2 neu extracellular and intracellular
domain protein; Status: On-going; Presentation
38. Project Title: FLT3 Expression in acute th
(1): 1) 27 IACR, February 2008, Ahmedabad.
myeloid leukaemia. PI: Dr. Hemangini
Vora; Dr. Shilin Shukla; CO-PI: Ms. Nilima 41. Project Title: A study of PRR1 and PRR2
Desai, Dr. Sonia Parikh, Dr. Shailesh Talati, proteins expression in AML and ALL
Dr. Manoj Shah, Dr. Swapan Desai, Dr. patients by flow cytometry. PI: Dr.
Pankaj Shah; Funding: The Gujarat Cancer Hemangini Vora, Dr. Shilin Shukla; CO-PI:
Society; Aim: FLT3 tyrosine kinase receptor is Dr. Sonia Parikh, Dr. Manoj Shah, Dr.
highly expressed in most acute leukemia and Pankaj Shah; Funding: Directorate of Medical
frequently mutated and might contribute to the Education and Research; Aim: Poliovirus
altered signalling that characterizes receptor-related (PRR1 and PRR2) proteins
73
belong to the Nectin-adhesion molecules expression of cytokeratin (a cytoskeletal
group, are expressed on endothelial cells and marker) and vimentin (a mesenchymal marker)
on CD34+ stem cells and mediate the was studied which indicated that gain of
organization of endothelial and epithelial vimentin expression and loss of cytokeratin
junctions. Both may participate not only in expression are indicators of biologically
adhesive reactions but also in transendothelial aggressive breast carcinomas. In light of these
migration of monocytes or in regulation of findings, the study aimed to answer – Does
intracellular functions through signal PRL-3 driven PI3K-AKT signaling pathway has
transduction. These molecules might also play a role in mediating EMT in breast cancer?
a role in the pathogenesis of leukemia. The Number of Patients (100); Number of Tests
goal is to study expression of PRR1 and PRR2 (1200); Name of Parameters: PRL-3, Snail,
on blasts of AML and ALL at initial diagnosis to Her-2 neu, fibronectin, vimentin, N-cadherin,
determine their diagnostic and prognostic E-cadherin, cytokeratin, alpha and gamma
relevance. Number of Patients (100); Number catenin; Status: On-going.
of Tests (230); Name of Parameters: PRR1 Medicinal Chemistry and
and PRR2 protein; Status: On-going; Pharmacogenomics:
th
Presentation (1): 1) 27 IACR, February 2008,
44. Project Title: To assess the medicinal
Ahmedabad.
value of wheatgrass as nutritional
42. Project Title: A study of methylation of supplement for rectification of anemia in
tumor suppressor gene PTEN in patients patients with solid tumour receiving
with breast cancer. PI: Dr. Hemangini Vora, platinum based chemotherapy. PI: Dr.
Dr. Shilin Shukla, Dr. Manoj Shah, Dr. Rakesh Rawal; CO-PI: Dr. Shilin Shukla;
Pankaj Shah; Funding: The Gujarat Cancer Funding: The Gujarat Cancer Society; Aim: To
Society; Aim: PTEN, the lipid phosphatase and assess the medicinal value of wheatgrass.
tensin homologue, is a key tumor suppressor. Number of Patients (25); Number of Tests
PTEN not only antagonizes tumorigenesis but (250; pretreatment blood samples + follow-up
also sensitizes breast cancer to targeted samples); Name of Parameters: IL5,6, TNF-a,
therapy with trastuzumab. The loss of PTEN TGF-b, hEPO; Status: On-going.
predicts resistance to trastuzumab treatment
45. Project Title: Assessment of LDH as a
and chemo/endocrine therapy. The goal of this
potential drug target. PI: Dr. Rakesh Rawal;
proposal is to study the role of PTEN and
CO-PI: Dr. Shilin Shukla; Funding: The
PI3K-AKT pathway in breast cancer. Number
Gujarat Cancer Society; Aim: Insilico analysis
of Patients (150; Malignant and Benign);
of LDH molecule using bioinformatics tools for
Number of Tests (700); Name of Parameters:
identification of putative binding sites and
PTEN gene, PTEN and AKT protein; Status:
designing of small molecule ligand for docking
On-going.
studies. Invitro analysis of the same designed
43. Project Title: Epithelial mesenchymal ligand to check its anticancer potentiality.
transition in breast cancer: Role of PRL-3 Number of Patients (NA); Number of Tests
mediated PI3K-AKT pathway. PI: Dr. (NA; pretreatment blood samples + follow-up
Hemangini Vora, Dr. Shilin Shukla, Dr. samples); Name of Parameters: Insilico study;
Manoj Shah, Dr. Pankaj Shah; Funding: The Status: On-going.
Gujarat Cancer Society; Aim: Epithelial–
46. Project Title: To evaluate the molecular
mesenchymal transition (EMT) is an important
mechanism of Imatinib resistance in
process during development by which
patients with CML. PI: Dr. Rakesh Rawal;
epithelial cells acquire mesenchymal,
CO-PI: Dr. Shilin Shukla; Dr. Sonia Parikh;
fibroblast-like properties and show reduced
Funding: The Gujarat Cancer Society; Aim:
intercellular adhesion and increased motility.
Gene expression and biochemical profiling to
Accumulating evidence points to a critical role
predict molecular mechanism that is
of EMT-like events during tumor progression
associated with cytogenetic response in
and malignant transformation, endowing the
chronic phase CML patients after 12 months of
incipient cancer cell with invasive and
Imatinib therapy. Number of Patients (100);
metastatic properties. In a preliminary work,
Number of Tests (300; pretreatment blood
74
samples + follow-up samples); Name of 49. Project Title: Population based cancer
Parameters: alpha-1 acid glycoprotein, serum registry - Ahmedabad Urban Agglomeration
Imatinib Insilico study; Status: On-going. Area. PI: Dr. Pankaj Shah, CO-PI: Dr. Shilin
Community Oncology & Medical Records: Shukla, Dr. Parimal Jivrajani; Funding:
National Cancer Registry Programme, ICMR;
47. Project Title: Rural Cancer Registry
Aim: (i) To study cancer patterns in the male
Project, Ahmedabad District. PI: Dr. Pankaj
and female population of all in the Ahmedabad
Shah; CO-PI: Dr. Shilin Shukla, Dr. Parimal
Urban Agglomeration Area, (ii) To have a valid
Jivrajani; Funding: National Cancer Registry
estimate of annual incidence of cancer cases
Programme, ICMR; Aim: (i) To study cancer
in the Ahmedabad Urban Agglomeration Area,
patterns in the male and female population of
(iii) To study cancer related mortality through
all ages in the rural district of Ahmedabad, (ii)
death records from the Municipal Corporation
To have a valid estimate of annual incidence of
and Municipality Offices, (iv) To initiate
cancer cases in the Ahmedabad District, (iii)
appropriate Epidemiological studies on specific
To study cancer related mortality through
problems which emerge as important and
death records from Village/Nagar Panchayat
relevant to the population of the Ahmedabad
Offices and from the information collected by
Urban Agglomeration Area, (v) To have a
health workers during home visits, (iv) To
valid estimate of time trends in the incidence of
initiate appropriate epidemiological studies on
cancer in the Ahmedabad Urban
specific problems which emerge as important
Agglomeration Area. Status: On-going;
and relevant to the population of the district.
Presentation: 1) Progress report of year 2007
Status: On-going; Presentation (1): 1) Report
for Population Based Cancer Registry –
of year 2004-2005 for Rural Cancer Registry in
Ahmedabad Urban Agglomeration Area in
XXIII Annual Review Meeting, NCRP, ICMR,
XXIII Annual Review Meeting, NCRP, ICMR,
Aizwal, November 2007; 2) Progress report of
November 2007, Aizwal.
year 2005-2006 for Rural Cancer Registry in
XXIII Annual Review Meeting, NCRP, ICMR, 50. Project Title: Development of an Atlas
November 2007, Aizwal. of Cancer in Gujarat. PI: Dr. Pankaj Shah;
CO-PI: Dr. Shilin Shukla, Dr. Parimal
48. Project Title: Ahmedabad District
Jivrajani; Funding: Government of Gujarat;
Cancer Control Programme. PI: Dr. Pankaj
Aim: (i) To obtain the overview of patterns of
Shah, CO-PI: Dr. Shilin Shukla, Dr. Parimal
cancer in different part of the Gujarat State, (ii)
Jivrajani; Funding: National Cancer Control
To calculate estimate of cancer incidence, (iii)
Programme, Government of India (MOHFW);
To strengthen the pathology department of
Aim: The ADCCP has been designed with a
major Government Hospitals and Medical
focus on: (i) prevention of cancer, (ii) early
Colleges in the field of oncopathology. Status:
detection, (iii) minimal treatment of common
On-going.
cancers, (iv) provision of supportive care in the
district. Inference: The important components 51. Project Title: Patterns of care and
of this project are 1) Intensive public survival studies of cancer cervix, cancer
education, particularly about prevention and breast and head & neck cancers. PI: Dr.
early diagnosis and identifying increasing risk Pankaj Shah; CO-PI: Dr. Shilin Shukla, Dr.
population, 2) Spreading cancer knowledge Parimal Jivrajani; Funding: National Cancer
through IEC and detection camps and mobile Registry Programme, ICMR; Aim: (i) To obtain
exhibition camps, 3) A total of 152 villages core identifying and diagnostic information in
nd
were covered in the 2 year ADCCP, 4) all patients with cancer cervix/ cancer breast/
Around 6000 patients were screened for head and neck cancers, (ii) To record details
common cancer, 5) Approximately patients of clinical stage and types of treatment in all
referred as suspicious at GCRI are Head & patients commenced on cancer directed
Neck and others – 45, Breast – 50 and Cervix treatment, (iii) To have periodic follow-up and
(VILI positive) – 141, 6) 8 patients have been record the patient and disease status in all
diagnosed with cancer and precancerous patients so as to have clinical stage and
cases (LSI9L/HSIL) are 3 and ASCUS are 27. treatment based survival on these sites of
Status: On-going. cancer. Status: On-going.
75
CLINICAL TRIALS
APRIL 2007 – MARCH 2008
Medical Oncology: response between Arm A (Paclitaxel plus AMG
1. Project Title: A phase III, multicenter, 706/placebo) and Arm B (Paclitaxel plus AMG
randomized, placebo-controlled, double- 706), to estimate the differences in objective
blind trial of AMG 706 in combination with response rate, progression-free survival time,
Paclitaxel and Carboplatin for advanced clinical benefit, overall survival and duration of
non-small cell lung cancer. PI: Dr. Kirti response between Arm B (Paclitaxel plus AMG
Patel; CO-PI: Dr. Shilin Shukla, Dr. Bharat 706) and Arm C (Paclitaxel plus Bevacizumab),
Parikh, Dr. Asha Anand, Dr. Shailesh Talati, to evaluate safety and tolerability in the three
Dr. Sandip Shah, Dr. Harsha Panchal, Dr. treatment arms. Number of Patients: (20);
Apurva Patel, Dr. Sonia Parikh; Funding Number of Tests: (168); Name of Parameters:
agency: Amgen Tech Pvt Ltd; Aim: To Response Rate: CT scan of chest, abdomen,
determine if treatment with AMG 706 in pelvis, brain, whole body bone scintigraphy;
combination with Paclitaxel and Carboplatin tumour responses will be measured and
improves overall survival compared to recorded by using the RECIST guidelines;
treatment with placebo in combination with toxicity: haematology (complete blood count
Paclitaxel and Carboplatin in subjects with including differential), coagulation factors (PTT,
advanced NSCLC. Number of Patients: (62); INR), blood chemistry (creatinine, total
Number of Tests: (2180); Name of Parameters: bilirubin, AST, ALT, alkaline phosphatase, free
response rate: CT or MRI of head, chest, T4, TSH, lipase, amylase), dipstic urine
abdomen and pelvis, bone scan; tumour analysis, pregnancy test (serum or urine),
responses will be measured and recorded by HER2 status; survival: OS, DFS by statistical
using the RECIST guidelines; toxicity: analyses; Status: On-going.
haematology panels: Hb, haematocrit, RBC, 3. Project Title: A randomized phase III trial
MCV, WBC, DC, platelets, ANC, chemistry of ALIMTA® (Pemetrexed) and Carboplatin
panels: total bilirubin, alkaline phosphatase, versus Etoposide and Carboplatin in
ALT, AST, BUN or urea, creatinine, glucose, extensive stage small cell lung cancer. PI:
bicarbonate, sodium, potassium, chloride, uric Dr. Kirti Patel; CO-PI: Dr. Shilin Shukla, Dr.
acid, LDH, albumin, s.amylase and s.lipase, Bharat Parikh, Dr. Asha Anand, Dr. Shailesh
free T4 and TSH , PTT, INR, urine analysis, Talati, Dr. Sandip Shah, Dr. Harsha Panchal,
survival: OS, DFS by statistical analyses; Dr. Apurva Patel, Dr. Sonia Parikh; Funding
Status: On-going. agency: Eli-lilly; Aim: To compare the overall
2. Project Title: A randomized phase II Trial survival of previously untreated patients with
of double-blind, placebo-controlled AMG ED-SCLC after treatment with Pemetrexed
706 in combination with Paclitaxel, or open- plus Carboplatin versus Etoposide plus
label Bevacizumab in combination with Carboplatin. Number of Patients: (100);
Paclitaxel, as first line therapy in women Number of Tests: (1400); Name of Parameters:
with HER2 negative locally recurrent or Response Rate: CT Scan and MRI, tumour
metastatic breast cancer. PI: Dr. Asha responses will be measured and recorded by
Anand; CO-PI: Dr. Kirti Patel, Dr. Shilin using the RECIST guidelines; toxicity:
Shukla, Dr. Bharat Parikh, Dr. Shailesh haematology (Hb, WBC, platelets, neutrophils),
Talati, Dr. Sandip Shah, Dr. Harsha Panchal, chemistry (total bilirubin, alkaline phosphatase,
Dr. Apurva Patel, Dr. Sonia Parikh; Funding ALT, AST, s.creatinine, LDH), serum and urine
agency: Amgen Tech Pvt Ltd; Aim: The pregnancy test, creatinine clearance, survival:
primary objective of the study is to determine if OS, DFS by statistical analyses; Status:
treatment with Paclitaxel and AMG 706 is Enrollment stopped.
superior to Paclitaxel plus AMG 706 /placebo 4. Project Title: A phase III randomized
in patients with HER2 negative locally recurrent controlled trial of Myocet, Trastuzumab and
or metastatic breast cancer based on objective Paclitaxel versus Trastuzumab and
response rates, Secondary: to estimate the Paclitaxel for first line therapy of metastatic
differences in progression-free survival time, breast cancer. PI: Dr. Harsha Panchal; CO-
clinical benefit, overall survival and duration of PI: Dr. Kirti Patel, Dr. Shilin Shukla, Dr.
76
Bharat Parikh, Dr. Asha Anand, Dr. Shailesh chemistry: (sodium, potassium, chloride,
Talati, Dr. Sandip Shah, Dr. Apurva Patel, bicarbonate, BUN, creatinine, uric acid,
Dr. Sonia Parikh; Funding agency: Sopherion glucose, AST(SGOT), ALT(GTP), total
Therapeutics Inc; Aim: Primary: Progression bilirubin, magnesium, calcium, phosphorus,
free survival (PFS) in the final analysis and alkaline phosphatase, total protein, albumin,
objective response rate in the interim analysis, LDH, CK, urine analysis, pregnancy test, ECG;
Secondary: overall survival objective response Survival: OS, DFS by statistical analyses;
rate (complete and partial) in the final analysis Status: On-going.
safety profile. Number of Patients: (56); 6. Project Title: A phase II safety and
Number of Tests: (1848); Name of Parameters: efficacy study of bavituximab plus
CT Scan and MRI of chest/abdomen/pelvis, paclitaxel and carboplatin in patients with
bone scan, MUGA scan or echocardiogram; previously untreated locally advanced or
tumour responses will be measured and metastatic NSCLC. PI: Dr. Apurva Patel;
recorded by using the RECIST guidelines; CO-PI: Dr. Kirti Patel, Dr. Shilin Shukla, Dr.
toxicity: haematology (CBC), chemistry: Bharat Parikh, Dr. Asha Anand, Dr. Shailesh
(sodium, potassium, chloride, bicarbonate, Talati, Dr. Sandip Shah, Dr. Harsha Panchal,
BUN, creatinine, uric acid, glucose, Dr. Sonia Parikh, Dr. Ashish Gupta; Funding
AST(SGOT), ALT(GTP), total bilirubin, agency: Clinigene International Pvt Ltd; Aim:
magnesium, calcium, phosphorus, alkaline Primary objective: To determine the overall
phosphatase, total protein, albumin, LDH, CK, response rate to a combination of Bavituximab
urine analysis, pregnancy test, ECG, HER2 plus Carboplatin and Paclitaxel in patients with
status, survival: OS, DFS by statistical locally advanced or metastatic NSCLC;
analyses; Status: On-going. Secondary objective: To determine time to
5. Project Title: Protocol EFC 10339: progression, duration of response, overall
International randomized study to evaluate survival and safety; Number of Patients: (49);
the addition of docetaxel to the Number of Tests: (392); Name of Parameters:
combination of Cisplatin-5-Fluorouracil CT scan chest and abdomen, tumour
(TCF) vs Cisplatin 5-Fluorouracil (CF) in the responses will be measured and recorded by
induction treatment of nasopharyngeal using the RECIST; toxicity: haematology,
carcinoma (NPC) in children and coagulation, d-dimer and serum chemistries,
adolescents. PI: Dr. Shailesh Talati; CO-PI: blood for anti chimeric antibodies, pregnancy
Dr. Kirti Patel, Dr. Shilin Shukla, Dr. Bharat test; Survival: OS, DFS by statistical analyses;
Parikh, Dr. Asha Anand, Dr. Shailesh Talati, Status: On-going.
Dr. Sandip Shah, Dr. Harsha Panchal, Dr. 7. Project Title: A phase II, open label,
Apurva Patel, Dr. Sonia Parikh, Dr. Amit randomized, multicenter trial of Pazopanib
Joshi; Funding agency: Sanofi Aventis; Aim: (GW786034) in combination with Lapatinib
To estimate the complete response (CR) rate (GW 572016) compared to Pazopanib
of TCF compared to CF in the induction monotherapy and Lapatinib monotherapy in
treatment of NPC, to determine the safety of subjects with FIGO Stage IV B or recurrent
TCF in comparisons to CF after induction or persistent cervical cancer with zero or
treatment of NPC, to determine overall one prior chemotherapy regimen for
response of TCF and CF on completion of advanced/recurrent disease. PI: Dr. Apurva
induction and consolidation, treatment of NPC: Patel; CO-PI: Dr. Kirti Patel, Dr. Shilin
to compare overall survival between TCF and Shukla, Dr. Bharat Parikh, Dr. Asha Anand,
CF, to characterize the role of EBV in the Dr. Shailesh Talati, Dr. Sandip Shah, Dr.
pathogenesis of NPC and investigate the Harsha Panchal, Dr. Sonia Parikh, Dr.
predictive value of the detection of the EBV- Ashish Gupta; Funding agency: The Glaxo
DNA in the peripheral blood of children with SmithKline group of Companies; Aim: To
NPC. Number of Patients: (100); Number of evaluate progression-free survival (PFS) of the
Tests: (2600); Name of Parameters: Response combination regimen versus each of the
Rate: CT Scan and MRI of head and neck, in monotherapy arm in subjects with FIGO Stage
addition CT/MRI scan of chest, abdomen, IV B or recurrent or persistent cervical cancer
pelvis, bone scan; tumour responses will be with zero or one prior chemotherapy regimen
measured and recorded by using the RECIST for advanced/recurrent disease. Number of
guidelines; toxicity: haematology (CBC), Patients: (180; 60 subjects/arm will be enrolled
77
in a 12 month period all over world [(40 (130); Number of Tests: (520), Name of
patients in India over 4 centers)]; Number of Parameters: Toxicity: routine haematology
Tests: (370); Name of Parameters: CT assessment, routine blood chemistry,
Scan/MRI chest and abdomen, pelvis, immunological assessment, urine analysis,
echocardiogram; tumour responses will be survival: OS, DFS by statistical analyses;
measured and recorded by using the RECIST Status: On-going.
guidelines; toxicity: haematology (HCT, HGB, 10. Project Title: A randomized, controlled
PT, WBC, DC), coagulation test: (PT, PTT, phase III trial of Picoplatin and Best
INR), chemistry: alkaline phosphatase, ALT, Supportive Care (BSC) versus BSC alone in
AST, bicarbonate, bilirubin patients with small cell lung cancer (SCLC),
(total/direct/indirect), BUN, chloride, creatinine, refractory or progressive within six months
calculated creatinine clearance, albumin, urea, of completing first-line, platinum containing
uric acid, calcium, magnesium, phosphate, chemotherapy. PI: Dr. Shailesh Talati; CO-
potassium, sodium, glucose, lactase PI: Dr. Kirti Patel, Dr. Shilin Shukla, Dr.
dehydrogenase (LDH), protein (total), urine Bharat Parikh, Dr. Asha Anand, Dr. Sandip
analysis, TFT; survival: OS, DFS by statistical Shah, Dr. Harsha Panchal, Dr. Apurva
analyses; Status: Completed. Patel, Dr. Sonia Parikh; Aim: Primary:
8. Project Title: An open label multicentric Overall survival, Secondary: The duration of
study to assess the efficacy and safety of response, progression free survival; Safety:
Recombinant Human Granulocyte Colony Safety will be evaluated by the incidence of
Stimulating Factor (Filgrastim) injections in laboratory and non-laboratory adverse events,
patients undergoing myelosuppressive including serious adverse events. Funding
chemotherapy. PI: Dr. Asha Anand; CO-PI: agency: Sopherion Therapeutics Inc; Number
Dr. Kirti Patel, Dr. Harsha Panchal, Dr. of Patients (20); Number of Tests: (540); Name
Apurva Patel, Dr. Sonia Parikh; Funding of Parameters: CT scan chest and abdomen;
agency: Cadila Healthcare Ltd; Aim: To assess tumour responses will be measured and
the efficacy and safety of Recombinant Human recorded by using the RECIST guidelines;
Granulocyte Colony Stimulating Factor toxicity: haematology (Hb, WBC, platelets,
(Filgrastim) injections in patients undergoing neutrophils), chemistry: alkaline phosphatase,
myelosuppressive chemotherapy. Number of ALT, AST, bicarbonate, bilirubin
Patients: (10); Number of Tests: (90); Name of (total/direct/indirect), BUN, chloride, creatinine,
Parameters: toxicity: haematology, blood calculated creatinine clearance, albumin, urea,
glucose, blood urea, s.creatinine, s.bilirubin, uric acid, calcium, magnesium, phosphate,
SGPT, alkaline phosphatase, urine analysis: potassium, sodium, glucose, lactase
protein, sugar; survival: OS, DFS by statistical dehydrogenase (LDH), protein (total), urine
analyses; Status: On-going. analysis, survival: OS, DFS by statistical
9. Project Title: An open lable dose finding analyses; Status: On-going.
prospective multicenter randomized parallel 11. Project Title: A randomized, open label
group study to asses the efficacy and multi-center study of XRP6258 at 25 mg/m2
safety of three different dose levels of AVI- in combination with Prednisone every 3
014 (G-CSF) compared with a standard weeks compared to Mitoxantrone in
dose of NEUPOGEN in breast cancer combination with Prednisone for the
patients at high (>20%) risk for treatment of hormone refractory metastatic
chemotherapy induced Neutropenia. PI: Dr. prostate cancer previously treated with a
Kirti Patel; CO-PI: Dr. Shilin Shukla, Dr. Taxotere- containing regimen. PI: Dr. Bharat
Bharat Parikh, Dr. Asha Anand, Dr. Shailesh Parikh; CO-PI: Dr. Kirti Patel, Dr. Shilin
Talati, Dr. Sandip Shah, Dr. Harsha Panchal, Shukla, Dr. Asha Anand, Dr. Shailesh Talati,
Dr. Apurva Patel, Dr. Sonia Parikh; Funding Dr. Sandip Shah, Dr. Harsha Panchal, Dr.
agency: AviGenics Inc; Aim: To assess the Apurva Patel, Dr. Sonia Parikh; Funding
dose response, efficacy and safety of three agency: Sanofi-Aventis; Aim: The aim of this
different dose levels of AVI-014 in breast study is to determine whether XRP6258 in
cancer patients at high risk for chemotherapy combination with Prednisone improves overall
induced Neutropenia. Number of Patients: survival when compared to Mitoxantrone in
78
combination with Prednisone; This study will pregnancy test (serum or urine), HER2 status,
also compare between the two treatment survival: OS, DFS by statistical analyses;
groups, prostate specific antigen response / Status: Completed.
progression, progression free survival, overall 13. Project Title: Protocol No: EPO-ANE-
response rate, pain response, pain 3010/Amendment INT-5: A randomized
progression, and safety. Number of Patients: open-label, multicenter, phase III study of
(720; patients will be participating in the trial Epoetin Alfa plus standard supportive care
worldwide at approximately 150 study centers versus standard supportive care in anemic
i.e. 5 patients per centre); Number of Tests: patients with metastatic breast cancer
(95), Name of Parameters: CT scan pelvis, receiving first-line standard chemotherapy.
thorax and abdomen, bone scan, X-ray PI: Dr. Shilin Shukla; CO-PI: Dr. Kirti Patel,
(pelvis), echocardiogram, tumour responses Dr. Bharat Parikh, Dr. Asha Anand, Dr.
will be measured and recorded by using the Shailesh Talati, Dr. Sandip Shah, Dr. Harsha
RECIST guidelines; toxicity: haematology Panchal, Dr. Apurva Patel, Dr. Sonia Parikh,
(complete blood count including differential, Dr. Ashish Gupta; Funding agency: Johnson
and platelets), blood chemistry (creatinine, total & Johnson; Aim: Primary: Progression free
bilirubin, AST, ALT, alkaline phosphatase, survival; Secondary: response rate, duration of
glucose, serum electrolytes, PSA, PK blood response, time to tumor progression (TTP),
draw, pain assessment by McGill-Melzack overall survival and thrombotic vascular event.
present pain intensity scale, survival: OS, DFS Number of Patients: (250); Number of Tests:
by statistical analyses; Status: On-going. (8250); Name of Parameters: CT Scan of
12. Project Title: An open label randomised abdomen, pelvis and chest, MRI/CT of brain,
phase II study of two different dosing echocardiography, bone scan, tumour
regimens of Capecitabine in combination responses will be measured and recorded by
with intravenous Docetaxel (Q3 W) in using the RECIST criteria; toxicity:
patients with locally advanced and/or haematology (Hb, RBC, WBC, platelets, DC),
metastatic breast cancer. PI: Dr. Shilin chemistry: alkaline phosphatase, ALT, AST,
Shukla; CO-PI: Dr. Kirti Patel, Dr. Bharat bicarbonate, bilirubin (total/direct/indirect),
Parikh, Dr. Asha Anand, Dr. Shailesh Talati, BUN, chloride, creatinine, albumin, cholesterol
Dr. Sandip Shah, Dr. Harsha Panchal, Dr. and triglycerides, GGT, uric acid, calcium,
Apurva Patel, Dr. Sonia Parikh, Dr. Ashish magnesium, phosphate, potassium, sodium,
Gupta; Funding agency: HoffMann-LaRoche- glucose, lactase dehydrogenase (LDH), protein
Inc; Aim: Primary: to demonstrate that the (total), urine analysis, serum beta-HCG;
combination of Capecitabine (825 mg/m2 BID survival: OS, DFS by statistical analyses;
daily d1-14) and Docetaxel (75mg/m2 iv d1 Status: Completed.
every 3 weeks) is at least equivalent to the 14. Project Title: To evaluate safety and
combination of capecitabine (1250 mg/m2 BID efficacy of G-CSF in treatment of
daily d1-14) and docetaxel (75mg/m2 iv d1 chemotherapy induced neutropenia in
every 3 weeks) in terms of time to disease patients with at least one episode of
progression or death due to any cause, clinically significant neutropenia (ANC
Secondary: Overall response rate, complete <1500) in past 3 months prior to enrollment
and partial responders, time to response and in the study. PI: Dr. Kirti Patel; CO-PI: Dr.
duration of overall response, time to treatment Shilin Shukla, Dr. Bharat Parikh, Dr. Asha
failure, and overall survival to evaluate effect of Anand, Dr. Shailesh Talati, Dr. Sandip Shah,
age on efficacy, toxicity, dose and Dr. Harsha Panchal, Dr. Apurva Patel, Dr.
pharmacokinetics. Number of Patients: (155); Sonia Parikh; Funding agency: Reliance Life
Number of Tests: (2635); Name of Parameters: Sciences; Aim: To study duration of
CT Scan /MRI, Bone scan, X-Ray, tumor neutropenia (ANC <1500/mm); to study
responses will be measured and recorded by duration of grade 4 neutropenia; to study time
using the RECIST criteria, toxicity: to ANC recovery, to determine safety. Number
haematology (complete blood count including of Patients: (100); Number of Tests: (1500);
differential), blood chemistry (creatinine, Name of Parameters: haematology (Hb,
creatinine clearance, total bilirubin, conjugated platelets, TLC, neutrophils, lymphocytes,
bilirubin, ASAT, ALAT, alkaline phosphatase, monocytes, eosinophils, basophils, absolute
LDH, serum electrolytes, serum folate level, neutrophil count), LFT chemistry (alkaline
79
phosphatase, ALT, AST, bilirubin, albumin); survival: OS, DFS by statistical analyses;
survival: OS, DFS by statistical analyses; Status: On-going.
Status: On-going. 17. Project Title: A phase II study of
15. Project Title: An open label multicentric Mycobacterium w in combination with
phase III study to access the efficacy and Etoposide in platinum refractory, advanced
safety of Pegylated form of recombinant or relapsed carcinoma ovary. PI: Dr. Asha
Human Granulocyte Colony Stimulating Anand; CO-PI: Dr. Kirti Patel, Dr. Shilin
Factor (Pegfilgrastim) injection in patients Shukla, Dr. Bharat Parikh, Dr. Shailesh
undergoing myelosuppressive Talati, Dr. Sandip Shah, Dr. Harsha Panchal,
chemotherapy. PI: Dr. Kirti Patel; CO-PI: Dr. Dr. Apurva Patel, Dr. Sonia Parikh; Funding
Shilin Shukla, Dr. Bharat Parikh, Dr. Asha agency: Cadila Pharmaceutical Pvt Ltd; Aim:
Anand, Dr. Shailesh Talati, Dr. Sandip Shah, Primary: To determine and compare the effect
Dr. Harsha Panchal, Dr. Apurva Patel, Dr. of this treatment on quality of life of the patients
Sonia Parikh; Funding agency: Cadila in the two arms; To determine and compare
Healthcare Limited; Aim: To assess the safety median survival in both the arms; Secondary:
and efficacy of pegylated form of Recombinant To determine and compare the response rate;
Human Granulocyte Colony Stimulating Factor To assess and compare the toxicity in both
(Pegfilgrastim) injection in patients undergoing arms; To study the bone marrow protective
myelosuppressive chemotherapy. Number of effect of Mw if any; Number of Patients: (21);
Patients: (100); Number of Tests: (1000); Number of Tests: (483); Name of Parameters:
Name of Parameters: hematology (HB, WBC, toxicity: CBC (WBC, RBC, haemoglobin,
platelets, DC), chemistry (blood urea nitrogen, haematocrit, MCV, MCH, MCHC, platelet
creatinine, bilirubin, ALT, alkaline phosphatase, count) urine routine/microscopic examination,
RBS), survival: OS, DFS; Status: On-going. alanine aminotransferase (ALT)/SGPT,
16. Project Title: A study of Mycobacterium aspartate aminotransferase (AST)/SGOT,
w in combination with Etoposide plus alkaline phosphatase, bilirubin, creatinine,
Cisplatin in advanced NSCLC. PI: Dr. Bharat BUN, electrolytes, HIV, HBsAg, ascites fluid
Parikh; CO-PI: Dr. Kirti Patel, Dr. Shilin cytology, response rate: X-ray chest, CT scan
Shukla, Dr. Asha Anand, Dr. Shailesh Talati, abdomen and pelvis, sonography abdomen
Dr. Sandip Shah, Dr. Harsha Panchal, Dr. and pelvis, FNAC; tumour responses will be
Apurva Patel, Dr. Sonia Parikh; Funding measured and recorded by using the RECIST
agency: Cadila Pharmaceutical Pvt. Ltd.; Aim: guidelines; survival: OS, DFS by statistical
Primary: To determine and compare the analyses; Status: Completed.
median survival time of patients in the two 18. Project Title: A phase III double blind,
arms; To determine and compare the effect of randomized study to evaluate the safety
this treatment on quality of life of the patients in and efficacy of BAL8557 vs a Caspofugin
the two arms; Secondary: To determine and followed by Voriconazole regimen in the
compare the response rate; To study the bone treatment of candidemia and other invasive
marrow protective effect of Mw if any. Number candida infections. PI: Dr. Kirti Patel; CO-PI:
of Patients: (50); Number of Tests: (1250); Dr. Shilin Shukla, Dr. Shailesh Talati, Dr.
Name of Parameters: CBC (WBC, RBC, Sandip Shah, Dr. Parijath Goswami, Dr.
hemoglobin, haematocrit, MCV, MCH, MCHC, Harsha Panchal, Dr. Apurva Patel, Dr. Sonia
platelet count) urine routine/microscopic Parikh; Funding agency: Basilea
examination, alanine aminotransferase Pharmaceutical Pvt Ltd; Aim: Primary: To
(ALT)/SGPT aspartate aminotransferase compare safety and efficacy of treatment with
(AST)/SGOT, alkaline phosphatase, bilirubin, Isavuconazole (WSA) vs a Caspofugin (CAS)
creatinine, BUN, electrolytes, HIV, HBsAg, – Voriconazole (VRC) regimen in patients with
ascites fluid cytology response rate: X-ray candidemia or other invasive candida
chest, CT scan abdomen and pelvis, infections; Secondary: To compare the effects
sonography abdomen and pelvis, CA 125; of the treatment on the response rate; time to
tumour responses will be measured and first negative blood culture; All cause 14 and
recorded by using the RECIST guidelines; 90 day mortality; To characterise the safety of
treatment with Isavuconazole; To characterise
80
the pharmacokinetics of Isavuconazole; and Joshi; Funding agency: GlaxoSmithkline; Aim:
cleavage product in the relevant patient Primary: To demonstrate the clinical efficacy of
population; Number of Patients: (46); Number recMAGE-A3+AS15 versus Placebo in NSCLC
of Tests: (1150); Name of Parameters: CBC after complete surgical resection; two co-
(WBC, RBC, haemoglobin, platelet count), primary objectives, efficacy in overall
chemistry: alkaline phosphatase, ALT, AST, population, efficacy in population of patients
bicarbonate, bilirubin (total/direct), chloride, who did not receive adjuvant chemotherapy,
creatinine, albumin, creatinine phosphokinase, Secondary: To evaluate and compare
GGT, uric acid, calcium, magnesium, recMAGE-A3+AS15 ASCI versus placebo with
phosphate, potassium, sodium, glucose, respect to other clinical and biological
lactase dehydrogenase (LDH), urine analysis, indicators of safety and efficacy; Translational
pregnancy testing in females at baseline; research: to examine the gene expression
survival: OS, DFS by statistical analyses; profile of primary tumour by microarray as
Status: On-going. defined prospectively in protocol and
19. Project Title: A double-blind randomized correlation to clinical outcome to treatment;
placebo-controlled phase III study to Number of Patients: (10); Number of Tests:
access the efficacy of recMAGE-A3 +AS15 (130); Name of Parameters: haematology (Hb,
antigen-specific cancer immunotherapeutic WBC, platelets, neutrophils), chemistry: (total
as adjuvant therapy in pts with resectable bilirubin, alkaline phosphatase, ALT, AST,
MAGE-3 positive NSCLC. PI: Dr. Kirti Patel; s.creatinine), anti-MAGE-A3, anti protd
CO-PI: Dr. Shilin Shukla, Dr. Bharat Parikh, antibody response, anti cpg antibody response,
Dr. Asha Anand, Dr. Shailesh Talati, Dr. 2-D gel electrophoresis; survival: OS, DFS by
Sandip Shah, Dr. Harsha Panchal, Dr. statistical analyses; Status: On-going.
Apurva Patel, Dr. Sonia Parikh, Dr. Amit
81
PUBLICATIONS
APRIL 2007 – MARCH 2008
No. Department/Division Authors Title Journal Citation
1 Radiodiagnosis Prakash Odedra Radiological quiz (Head and Neck): Cavernous Indian J Radiology and
Shreedevi Patel haemangioma of the tongue and oral cavity Imaging, 17:138; 2007
Kirti Goswami
Dhara Patel
2 Himanshu Soni Intraabdominal gossypiboma Gujarat Medical J,
Shreedevi Patel 3:67-68; 2008
Kirti Goswami
Kavita Patel
Himanshu Vadodaria
THE GUJARAT CANCER & RESEARCH INSTITUTE
3 Surgical Oncology Bhavna Parikh Liposarcoma of breast: A case report Eur J Gyneconcology,
A Ohri 28:425-427; 2007
Mittal Desai
V Proof
Shashank Pandya
82
Rajendra Dave
4 Mittal Desai Malignant melanoma of rectum: A rare entity The Internet J of
Bhavna Parikh Surgery, 10:1-7; 2007
Jayesh Prajapati
Phulkumari Talukdar
Rajendra Dave
5 Bhavna Parikh Primary retroperitoneal hydatid cyst Nigerian J Surgery,
Mittal Desai 29:29-31; 2008
Phulkumari Talukdar
Jayesh Prajapati
Shashank Pandya
Rajendra Dave
6 Rajen Tankshali Carcinoid of ampulla of vater - A case report Indian J Cancer,
Jayesh Patel 44:90-92; 2007
Narendra H
Rohan Vinayak
Abhinandan H
THE GUJARAT CANCER & RESEARCH INSTITUTE
No. Department/Division Authors Title Journal Citation
7 Surgical Oncology Narendra H Bipaddle PMMC vs deltopectoral flap for Gujarat J
Rohan Vinayak reconstruction of skin defects in cancer of Otorhinolaryngology: An
Abhinandan H buccal mucosa Head and Neck
Jayesh Patel Surgery,
Rajen Tankshali 4:11-12; 2007
8 Medical Oncology Kirti Patel Myasthenia gravis with imatinib Gujarat Medical J,
Sandip Shah 3:75-76; 2008
Apurva Patel
Ratnesh Shrivastav
Kiran Kattimani
Abhishek Kakroo
9 Bharat Vasvani Non-hodgkin’s lymphoma of tongue – Case report Indian J of Medical
Mithun Shah & Paediatric
Pankaj Shah Oncology, 29:59-61;
Bharat Parikh 2008
V Proof
83
Asha Anand
Gopal Sharma
10 Sandip Shah Reduced intensity stem cell transplantation Hematology Today 2008,
Silky Chotai 63:501; 2008
11 Purvish Parikh Role of imatinib mesylate in chronic myeloid CML - An Update with
Tapan Saikia leukemia Indian Experience,
AK Tripathi 11:89; 2008
Sandip Shah
Apurva Sheth
Pankaj Shah
12 Anaesthesiology Sachin Mittal Intraoperative complication in a case of Gujarat Medical J,
Dipika Patel paraganglioma 3:81-83; 2008
Madhuri Bhade
Bipin Patel
No. Department/Division Authors Title Journal Citation
13 Radiotherapy Rakesh Vyas Role of interstitial brachytherapy using MUPIT in Int J Radiation Oncology
Jayprakash Neema locally advanced gynaecological malignancies Biology Physics,
U Suryanarayan 69:5406; 2007 (abstract)
Chirag Amin
Kinjal Jani
14 Pooja Nandwani Patel Retrospective analysis of role of interstitial J Cancer Research and
Rakesh Vyas brachytherapy using template (MUPIT) in locally Therapeutics, 3:111-115;
Jayprakash Neema advanced gynaecological malignancies 2007
U Suryanarayan
Devang Bhavsar
Kinjal Jani
15 Phulkumari Talukdar Skin metastasis from head and neck cancer Gujarat J
THE GUJARAT CANCER & RESEARCH INSTITUTE
Bhavna Parikh Otorhinolaryngology: An
Rimpi Sarin Head and Neck
Rakesh Vyas Surgery, 4:10-12; 2008
V Proof
84
Rajendra Dave
16 Cell Biology Sonal Bakshi Characterisation of a small familial supernumerary Cancer Genetics &
Bhavna Dave marker chromosome in a patient with adult-onset Genome Research (In
Warren Sanger tongue cancer press)
Shailesh Patel
Pina Trivedi
Manisha Brahmbhatt
17 Biochemistry Jayendra Patel Utility of urinary biomarkers in oral cancer Asian Pacific J
Research Shilin Shukla Cancer Prevention,
Hiten Patel 8:229-235; 2007
Kiran Kothari
Pankaj Shah
Prabhudas Patel
18 Franky Shah Significance of alterations in plasma lipid profile Integrative Cancer
Shilin Shukla levels in breast cancer Therapies, 7:33-41;
Pankaj Shah 2008
Hiten Patel
Prabhudas Patel
THE GUJARAT CANCER & RESEARCH INSTITUTE
No. Department/Division Authors Title Journal Citation
19 Biochemistry Manisha Shah Tissue and serum α-2-3 and α-2-3 linkage specific Glycoconjugates J,
Research Shaila Telang sialylation changes in oral carcinogenesis 3:279-290; 2008
Pankaj Shah
Prabhudas Patel
20 Beena Patel Lipid peroxidation, total antioxidant status and total Integrative Cancer
Upendra Rawal thiol levels predict overall survival in patients with Therapies, 6:365-371;
Tina Dave oral squamous cell carcinoma 2007
Rakesh Rawal
Shilin Shukla
Pankaj Shah
Prabhudas Patel
21 Beena Patel Association of antioxidant enzymes, GST-μ and American J Clinical
Upendra Rawal tobacco habits with oral cancer Oncology, 2008 (In
Shilin Shukla Press)
V Proof
Pankaj Shah
85
Prabhudas Patel
22 Beena Patel Tobacco, antioxidant enzymes, oxidative stress Free Radicals and
Pankaj Shah in oral cancer Antioxidants in Health
Upendra Rawal and Disease, 129-146;
Prabhudas Patel 2007
23 Receptor & Growth Dave Heena Circulating levels of transforming growth factor GCS Research Bulletin,
Factor Lab Sunil Trivedi β1 (TGF-β1) in breast cancer patients 9–10:70–77; 2007
Trupti Trivedi
Rohini Shah
Manoj Shah
CONFERENCE PRESENTATIONS
APRIL 2007 – MARCH 2008
No. Department/ Presenting Title Conference (Presentation Mode)
Division Author
1 Pathology Priti Trivedi Accuracy of squash preparation in frozen 6th Evidence Base Management
diagnosis of CNS tumor in CNS Tumor, Mumbai,
February 2008 (Oral)
2 Biren Parikh Immunophenotyping of acute leukemia - A Advanced Techniques in
GCRI experience Haematological Malignancies,
Mumbai, October 2007 (Poster)
3 Blood Bank Jayshree Shukla Maximizing the yield stem cell harvest ISBTI Conference, Bhopal,
November 2007 (Oral)
THE GUJARAT CANCER & RESEARCH INSTITUTE
4 Microbiology Parijath Goswami Antibiotics resistance pattern in the bacterial 3rd International Congress of
isolates causing infections in the Asia Pacific Society of Infection
cancer patients Control, Kuala Lumpur, Malaysia,
V Proof
July 2007 (Oral)
86
5 Radiodiagnosis Himanshu Soni Retinoblastoma in developing country – USG Radiological Society of North
Doppler and CT findings America – 2007 Educational
Exhibit, Chicago, USA,
November 2007 (Oral)
6 Surgical Oncology Narendra H Pattern of nodal metastasis in T4 buccal NATCON IASO 2007,
mucosal cancer Ludhiana, September 2007 (Poster)
7 Gopal Gajjar Total laryngectomy NATCON IASO 2007,
Ludhiana, September 2007 (Oral)
8 Gynaecological Ava Desai Surgical pelvic anatomy 51st AICOG, New Delhi,
Oncology February 2008 (Oral)
9 Meeta Mankad Screening for cervical cancer and preinvasive National CME on Obstetrics and
lesions of the cervix Gynaecology, New Delhi,
November 2007 (Oral)
10 Ronak Bhanshali Preservation of ovarian function in malignant International Conference of
ovarian germ cell tumors in adolescent girls - Association of Paediatric
The GC & RI experience Oncologists, Mumbai, November
2007 (Poster)
THE GUJARAT CANCER & RESEARCH INSTITUTE
No. Department/ Presenting Title Conference (Presentation Mode)
Division Author
11 Gynaecological Sonali Garg Sarcoma of uterus – Six years experience at YUVA FOGSI West Zone
Oncology GC & RI Conference, Ahmedabad,
October 2007 (Oral)
12 Bijal Patel Borderline epithelial ovarian tumor: Six years
experience at GC & RI
13 Ruchi Arora Conservative surgery in stage IC epithelial
ovarian cancer: A case report
14 Carcinoma ovary
15 Vishal Dave Our experience of bulky cervical cancer stage
IB2 and IIA (FIGO): Treated with radical
hysterectomy and pelvic node dissection and
role of adjuvant radiotherapy
16 Hiten Arye Colposcopic prediction in patients having normal Annual Conference of AGOI,
V Proof
pap’s smear Madurai, November 2007 (Oral)
87
17 Kamlesh Mishra Retrospective analysis of 117 patients of
carcinoma endometrium treated at GC & RI,
Ahmedabad: A regional cancer institute
18 Facts about carcinoma endometrium - FOGSI, New Delhi, February
A retrospective study at GC & RI, Ahmedabad: 2008 (Oral)
A regional cancer institute
19 Apurva Gupta Vaginal delivery of breech still a role after FOGSI, Calcutta, 2007 (Oral)
Hannah trial - A study of 361 patients
20 Medical Oncology Kirti Patel Cefipime monotherapy in paediatric patients SIOP, Mumbai, October 2007
in febrile neutropenia (Poster)
21 Sandip Shah Experience of peripheral blood stem cell
collection in paediatric patients
22 A retrospective review of allogenic BMT at ESO Conference, Mumbai,
GC & RI March 2008 (Poster)
23 Ratnesh Single institute review of Hodgkin’s disease SIOP, Mumbai, October 2007
Shrivastav in children at GCRI (Poster)
No. Department/ Presenting Title Conference (Presentation Mode)
Division Author
24 Medical Oncology Kiran Kattimani Teratoid Wilms tumour experience at a SIOP, Mumbai, October 2007
regional cancer center in India (Poster)
25 Gopal Sharma Paediatric brain tumours experience at a
regional cancer centre in India - GCRI
26 Solitary extramedullary lymphoid blast crisis ESO Conference, Mumbai,
(B cell) in chronic myeloid leukemia : An March 2008 (Poster)
unusual presentation
27 Tushar Patil An overview of primary extra nodal non- ESO Conference, Mumbai,
hodgkin’s lymphoma cases presenting September 2007 (Poster)
at GC & RI
THE GUJARAT CANCER & RESEARCH INSTITUTE
28 Bharat Vasvani Ph +ve AML and their outcome
29 Cytogenetics in denovo AML - GC & RI ESO Conference, Mumbai,
V Proof
experience September 2007 (Oral)
88
30 Anaesthesiology Vinay Solanki Anaesthetic management of bilateral carotid body GISACON, Rajkot, October
tumor - A case report 2007 (Oral)
31 Bhavna Shah Chronic pain syndrome in women ISSPCON, Vellore, January
2008 (Oral)
32 Palliative care in cancer patients Advancement in Cancer
Treatment - A Workshop for
Surgeons, Mahesana, March
2008 (Oral)
33 Priti Sanghavi Cancer chemotherapy and its anaesthetic GISACON, Rajkot, October
implications 2007 (Oral)
34 Dipika Patel Management of neuropathic pain syndrome GIMACON, Visnagar, October
2007 (Oral)
35 Pain and palliative care Training Programme of District
Medical Officers, Ahmedabad,
November 2007 (Oral)
THE GUJARAT CANCER & RESEARCH INSTITUTE
No. Department/ Presenting Title Conference (Presentation Mode)
Division Author
36 Radiotherapy Rakesh Vyas Live workshop on MUPIT AROICON, Chennai, December
2007 (Oral)
37 Devang Bhavsar Role of radiotherapy in carcinoma of prostate Indo-American Collaborative
Workshop on Radiotherapy,
Ahmedabad, November 2007 (Oral)
38 Maitrik Mehta Comparison of hypofractionated SRT 5th West Zone Chapter of AROI,
versus SRS in patients with brain metastasis Padhar, Betul, February 2008
(Oral)
39 Prognostic factors and survival assessment by Evidence Based Management of
recursive partitioning analysis criteria in patients CNS Tumors in India, Mumbai,
of carcinoma breast with brain metastasis March 2008 (Poster)
40 Pooja Nandwani Patel Comparison of hypofractionated SRT versus International Conference on
SRS in patients with brain metastasis Oncology – Oncology Current
V Proof
Trends, Pune, August 2007
89
(Oral)
41 Comparison of X-Knife versus surgery in AROICON, Chennai, December
patients of arteriovenous malformation of brain 2007 (Oral)
(AVM)
42 Rushi Panchal IMRT in head and neck cancer 5th West Zone Chapter of AROI,
Padhar, Betul, February 2008
(Poster)
43 Mayur Munshi Measurement of neutron dose in 18 MV Association of Medical Physicists
photons and various energies of electrons in of India, Srinagar, November
SL20 LINAC 2007 (Poster)
44 Cell Biology Pina Trivedi AML with complex karyotype: A subtype 27th IACR, Ahmedabad, February
candidate for M- FISH 2008 (Poster)
45 Manisha Brahmbhatt Complex chromosomal rearrangements in CML
patients: Making simple with M-FISH
46 Sejal Purani Clinical implication of BCR-ABL fusion gene
detection in CML by FISH
No. Department/ Presenting Title Conference (Presentation Mode)
Division Author
47 Cell Biology Ramesh Iyer Targeted therapy in cancer: The chronic myeloid Healthcare: Redefined 2008,
leukemia model Gujarat University, Ahmedabad,
March 2008 (Oral)
48 Molecular Dhara Gajjar Nanotechnology: A basis for next revolution in Poster Competition, GC&RI,
Endocrinology I cancer Ahmedabad, October 2007
(Poster)
49 p27 as a prognostic factor in breast carcinoma 27th IACR, Ahmedabad, February
2008 (Poster)
50 Rachana Shah Clinical usefulness of CEA and CA19-9 in
pancreatic carcinoma
THE GUJARAT CANCER & RESEARCH INSTITUTE
51 Molecular Nandita Ghosh Role of cell cycle regulatory proteins in patients
Endocrinology II with colorectal adenocarcinoma
52 Trupti Trivedi Stat3: An early event in oral carcinogenesis
V Proof
90
53 Toral Kobawala Stem cells: A cure to cancer? Poster Competition, GC & RI,
Ahmedabad, October 2007
(Poster)
54 Molecular alterations in oral carcinogenesis: 27th IACR, Ahmedabad, February
Significant risk predictors in malignant 2008 (Poster)
transformation and tumor progression
55 Kinjal Patel Role of telomerase and its subunits in breast
cancer
56 Nanotechnology: A basis for next revolution in Poster Competition, GC & RI,
57 Bindu Yagnik cancercancer Ahmedabad, October 2007
(Poster)
58 Biochemistry Prabhudas Patel Tobacco usage and antioxidant status: 2nd International Symposium on
Research The major culprits for oral cancer? Translation Research - Natural
Products and Cancer, Lonavla,
December 2007 (Oral)
THE GUJARAT CANCER & RESEARCH INSTITUTE
No. Department/ Presenting Title Conference (Presentation Mode)
Division Author
59 Biochemistry Prabhudas Patel Emerging trends in molecular biology of human National Conference on
Research oral cancer Apoptosis and Cancer,
Vadodara, December 2007 (Oral)
60 Contemporary issues in molecular biology of Dia-Can 2007, Annamalai
oral cancer in India University, Annamalai Nagar,
December 2008 (Oral)
61 Jayendra Patel Study of nitric oxide and antioxidant enzymes 27th IACR, Ahmedabad, February
in oral pre-cancers and oral cancer 2008 (Poster)
62 Franky Shah Significance of alterations in plasma non- 2nd International Symposium on
enzymatic antioxidants in breast cancer Translational Cancer Research,
Lonavala, December 2007
(Poster)
63 Clinical relevance of MMP-2 and MMP-9, 27th IACR, Ahmedabad, February
V Proof
TIMP-1 and TIMP-2 in breast cancer 2008 (Poster)
91
α
64 Vandana Patel Significance of Sialyl Lewis-X and E-cadherin 34th Association of Clinical
in oral cancer and oral pre-cancer Biochemists of India, New Delhi,
December 2007 (Poster)
65 GST isoenzymes and GST GR levels in National Conference on
oral cancer Apoptosis and Cancer,
Vadodara, December 2007
(Poster)
66 Significance of sialylation changes in oral 27th IACR, Ahmedabad, February
cancer and oral pre-cancer 2008 (Poster)
67 Hetvi Patel Tissue and serum α -2,3 and -2,6 linkage 34th Association of Clinical
specific sialylation changes in oral Biochemists of India, New Delhi,
carcinogenesis December 2007 (Poster)
68 Significance of alterations in plasma non- Healthcare: Redefined 2008,
enzymatic antioxidants in breast cancer Gujarat University, Ahmedabad,
March 2008 (Poster)
No. Department/ Presenting Title Conference (Presentation Mode)
Division Author
69 Biochemistry Hetvi Patel Interplay between antioxidants: Role in 27th IACR, Ahmedabad, February
Research breast cancer 2008 (Poster)
70 Receptor & Growth Heena Dave TGF-α signaling in early versus advanced
Factor Lab human breast cancers
71 Trupti Trivedi MMP-2 (Gelatinase A) and its activity in 27th IACR, Ahmedabad, February
human meningioma 2008 (Oral)
72 Apexa Raval Insulin like growth factor-I: Implication in 27th IACR, Ahmedabad, February
breast cancer prognostication 2008 (Poster)
73 Pankil Bhatt Vascular endothelial growth factor in
breast cancer: Influence of sample type
THE GUJARAT CANCER & RESEARCH INSTITUTE
74 Poonam Mehta Retinoic acid receptors in breast cancer
75 Immunohisto- Nilima Desai Regulators of apoptosis in human breast National Conference on
V Proof
chemistry cancer Apoptosis and Cancer,
92
Vadodara, December 2007
(Poster)
76 P53 exon 5 and 7 and p53 protein analysis 27th IACR, Ahmedabad, February
in breast cancer 2008 (Poster)
77 Kruti Rajvik Investigation of Her-2 neu protein, Her-2 codon 32nd Conference of Gujarat
655 SNP frequency and PTEN protein Pathologists and Microbiologists,
alterations in breast cancer Vadodara, February 2008 (Oral)
78 A study of expression of PTEN protein in 27th IACR, Ahmedabad, February
benign and malignant breast diseases 2008 (Poster)
79 Shalvi Mehta Epithelial mesenchymal transition in breast 32nd Conference of Gujarat
carcinoma Pathologists and Microbiologists,
Vadodara, February 2008 (Oral)
80 Loss of Her-2 neu ECD predicts worse 27th IACR, Ahmedabad, February
clinical outcome in Her-2 neu ICD positive 2008 (Poster)
breast cancer
THE GUJARAT CANCER & RESEARCH INSTITUTE
No. Department/ Presenting Title Conference (Presentation Mode)
Division Author
81 Immunohisto- Birva Brahmbhatt Herbal medicine in cancer management Seminar on Natural Compounds
chemistry in Management of Cancer,
Ahmedabad, December 2007
(Poster)
82 BAG-1, an antiapoptotic protein: Down National Symposium on
regulation in chewing tobacco mediated Apoptosis and Cancer,
tongue carcinogenesis Vadodara, December 2007
(Poster)
83 Expression of markers of apoptosis, 27th IACR, Ahmedabad, February
angiogenesis and hormone receptors in 2008 (Poster)
endometrial carcinoma
84 Nupur Patel FLT3 and PRR2 protein expression in acute
myeloid leukemia
V Proof
85 Himanshi Trivedi Herbal medicine in cancer management Seminar on Natural Compounds
93
in Management of Cancer,
Ahmedabad, December 2007
(Poster)
86 Medicinal Chemistry Rakesh Rawal Role of bioinformatics in drug discovery UGC sponsored Seminar on
& Pharmaco- Bioinformatics: Leads in
genomics Gujarat, Gujarat University,
March 2008 (Oral)
CONFERENCE ATTENDED
APRIL 2007– MARCH 2008
Department / Name Conference
Division
Pathology Dhaval Jetly International CME in Surgical Pathology & Cytopathology, Mumbai, November 2007
Priti Trivedi 32nd Conference of Gujarat Association of Pathologists and Microbiologists, Vadodara,
August 2007
Priti Trivedi Update in Surgical Pathology 2007, Mumbai, August 2007
Lopa Mody
Priti Trivedi Evidence Based Management of Cancers in India, Mumbai, February 2008
Kaushambi Shukla National Meeting on Guidelines for Immunophenotyping of Haematolymphoid Neoplasms and
THE GUJARAT CANCER & RESEARCH INSTITUTE
Biren Parikh Workshop on Detection of Minimal Residual Disease & Analysis of Flow Cytometric Data,
Mumbai, March 2007
Biren Parikh Advanced Techniques in Haematological Malignancies, Mumbai, October 2007
V Proof
94
14th National CME in Haematology and Haemato-Oncology, Mumbai, January 2008
Microbiology Parijath Goswami 2nd National Conference of Infectious Diseases Society of India, Hyderabad, January 2008
Blood Bank Jayshree Shukla MAPCON 2007 - Pre Conference Workshop on Transfusion Medicine, Apheresis and PBSC
Harvest, Navi Mumbai, October 2007
The Regional Thalassemia Conference, Ahmedabad, October 2007
Ketki Meghiawala ISBTI Conference, Bhopal, November 2007
Radiodiagnosis Kirti Goswami Evidence Based Management of Cancer in India, Mumbai, March 2008
Saumil Desai
Ajay Upadhyay
Himanshu Vadodaria Radiological Society of North America, Chicago, USA, November 2007
Saumil Desai CME of ICRI and Annual Conference of IRIA, Bhopal, April 2008
Shikha Pandhi 2nd MR Spectroscopy Workshop, Mumbai, June 2007
Kavita Patel
Shikha Pandhi Color Doppler Workshop, Ahmedabad, March 2008
Surgical Oncology Shakuntala Shah Bleeding Management in General Surgery, Mumbai, August 2007
THE GUJARAT CANCER & RESEARCH INSTITUTE
Department / Name Conference
Division
Surgical Oncology Shakuntala Shah National Conference ACRSICON 2007, Ahmedabad, September 2007
Kiran Kothari
Mukul Trivedi
Kiran Kothari CME on Conservative Breast Surgery, Diu, April 2007
39th Annual Meeting of ASCO, Chicago, USA, May 2007
Kiran Kothari NATCON IASO 2007, Ludhiana, September 2007
Mukul Trivedi
Kiran Kothari ASIMANICON 2007, Imphal, October 2007
Symposium on Recent Trends in Cancer Research & Treatment, Kolkata, October 2007
Excellence in Oncology 2007, Kolkata, November 2007
1st CME/Operative Workshop in Head and Neck Oncology, Miraj, February 2008
8th World Congress - IHPBA 2008, Mumbai, February 2008
V Proof
95
Jayesh Patel Cancer CI – 2008, Hyderabad, February 2008
Jayesh Prajapati Workshop on Laparoscopy Surgery in Oncology, Coimbatore, November 2007
Mukul Trivedi
Paediatric Surgery Sudhir Chandna SIOP Conference, Mumbai, November 2007
Nitin Joshi
A Kiran
Neurosurgery Navin Patel 4th International Symposium of Psychiatry, Vienna, Austria, October 2007
Dipak Patel 9th National Skull Base Surgery Conference, New Delhi, October 2007
Parimal Tripathi
Tejas Patel
Dipen Patel
Tejas Patel 56th Annual Conference of Neurological Society of India, Agra, December 2007
Dipen Patel
Gynaecological Kalpana Dave CME jointly organised with SOGOG, Bhavnagar, April 2007
Oncology
Kalpana Dave Ahmedabad Forum of Infection Prevention, Hospital Infection Society on India, Gujarat
Anjana Chauhan Chapter, Ahmedabad, October 2007
Department / Name Conference
Division
Gynaecological Kalpana Dave YUVA FOGSI West Zone Conference, Ahmedabad, October 2007
Oncology Ava Desai
Meeta Mankad
Pariseema Dave
Anjana Chauhan
Ronak Bhanshali
Kalpesh Prajapati
Kalpana Dave 2nd International Conference of BJMC Alumni Association, Ahmedabad, December 2007
Anjana Chauhan
Ava Desai 1st International Conference on Ovarian Cancer, Bangalore, April 2007
Meeta Mankad
THE GUJARAT CANCER & RESEARCH INSTITUTE
Ava Desai 5th TMH-WCI Conference on Advanced Breast and Ovarian Cancers, Mumbai, October 2007
Pariseema Dave
Hiten Arye
V Proof
Kamlesh Mishra
96
Ava Desai Annual Conference of AGOI, Madurai, November 2007
Pariseema Dave
Shilpa Patel
Hiten Arye
Kamlesh Mishra
Ava Desai Annual Conference of Indian Association of Gynaecological Endoscopists, Ahmedabad,
June 2007
Anjana Chauhan Workshop of Endoscopic Laparoscopic Surgeries & Annual Conference of Indian
Association of Gynaecological Endoscopists, Ahmedabad, June 2008
Kamlesh Mishra Workshop on Gynaec Oncology of FOGSI, New Delhi, February 2008
Medical Oncology Kirti Patel Indian Society of Nuclear Medicine Conference, Udaipur, October 2007
Shilin Shukla Breast Cancer Conference, Mumbai, October 2007
International Conference of Clinical Oncology, Hyderabad, November 2007
Bharat Parikh GI Expert Forum, Goa, July 2007
ISMPO Meeting on Febrile Neutropenia, Bhutan, August 2007
Empiric Antibiotic Therapy in Febrile Neutropenia, IDSA Guidelines, Gurgaon, September 2007
THE GUJARAT CANCER & RESEARCH INSTITUTE
Department / Name Conference
Division
Medical Oncology Bharat Parikh SIOP Conference, Mumbai, November 2007
Mithun Shah
Suman Mittal
Bharat Vasvani
Kiran Kattimani
Bharat Parikh Second Meeting of the Task Force on National Retinoblastoma Registry, New Delhi,
November 2007
National Haematology CME Programme, Mumbai, January 2008
1st Asian Conference on Breast Cancer, New Delhi, February 2008
Bharat Parikh ESO - Leukemias Molecular Insights to Treatment Paradigms, Mumbai, March 2008
Sandip Shah
Sonia Parikh
Tushar Patil
Gopal Sharma
V Proof
Bharat Vasvani
97
Abhishek Kakroo
Bharat Parikh 18th Conference of Asian Pacific Association for the Study of the Liver, Seoul, South
Korea, March 2008
Asha Anand Haematopoietic Stem Cell Transplant Meeting, CMC, Vellore, March 2008
Sandip Shah
Sandip Shah 43rd ASCO Meeting, Chicago, IL, USA, June 2007
Sonia Parikh
Apurva Patel MAGRIT (1.9493) Investigator’s and Monitor’s Meeting, Singapore, July 2007
Apurva Patel INDOX Training on Phase 1 Clinical Trial, Oxford University, Oxford, UK,
Sonia Parikh September 2007
Sonia Parikh Principal Investigator Meeting by Elli Lilly for protocol H3E-MC-S103, New Delhi,
November 2007
Dinesh Sheth CME on CML, Mumbai, April 2007
Mithun Shah
Suman Mittal
Bharat Vasvani
Gopal Sharma
Department / Name Conference
Division
Medical Oncology Gopal Sharma One day Symposium on Leukemia and Management of Colorectal Cancer, Mumbai,
Bharat Vasvani July 2007
Tushar Patil
Tushar Patil ASH UPDATE, Mumbai, December 2007
Gopal Sharma
Bharat Vasvani
Abhishek Kakroo
Mithun Shah Haematology Update, Mumbai, January 2008
Kiran Kattimani
Gopal Sharma
Kamlesh Shah
THE GUJARAT CANCER & RESEARCH INSTITUTE
Anaesthesiology Geeta Joshi 23rd National Conference of Indian Society Study of Pain, Vellore, January 2008
Bhavna Shah
Priti Sanghavi
V Proof
98
Bhavna Shah GISACON, Rajkot, October 2007
Priti Sanghavi
Bijal Shah
Dipika Patel GIMACON, Visnagar, October 2007
Bipin Patel Advanced Regional Anaesthesia and Ultrasound Workshop, Ahmedabad, March 2008
Geeta Joshi
Bhavna Shah
Dipika Patel
Vaibhavi Javeri Anaesthesia Review Course, Mumbai, April 2007
Bhumika Pathak
Sachin Mittal National CME on Emergency and Trauma, New Delhi, August 2007
Radiotherapy Rakesh Vyas AROICON, Chennai, December 2007
Mainank Patel
Chirag Amin
Rakesh Vyas Association of Medical Physicists of India, Hyderabad, Andhra Pradesh, July 2007
Association of Medical Physicists of India, Tamilnadu, August 2007
American Society of Radiotherapy and Oncology (ASTRO), LA, USA, October 2007
THE GUJARAT CANCER & RESEARCH INSTITUTE
Department / Name Conference
Division
Radiotherapy Rakesh Vyas 5th West Zone Chapter of AROI, Betul, Madhya Pradesh, February 2008
Jaiprakash Neema
Maitrik Mehta
Rushi Mehta
Jaiprakash Neema Evidence based management of CNS tumors in India, Mumbai, February 2008
Devang Bhavsar
Maitrik Mehta
Devang Bhavsar RTOG IGRT Workshop, Florida, April 2007
Frameless SRS & SRT Workshop, Mobil, August 2007
Medical Physics Om Prakash 5th Annual Nuclear Medicine Conference, Udaipur, September 2007
Mayur Munshi Association of Medical Physicists of India, Srinagar, November 2007
Cell Biology Sonal Bakshi Healthcare: Redefined 2008, Gujarat University, Ahmedabad, March 2008
V Proof
Receptor & Growth Sunil Trivedi International Course in Molecular Epidemiology, Mumbai, September 2007
99
Factor Lab
Immunohistochemistry Hemangini Vora National Meeting on Guidelines for Immunophenotyping of Hematolymphoid Neoplasms and
Nilima Desai Workshop on Detection of Minimal Residual Disease & Analysis of Flow Cytometric Data,
Mumbai, March 2007
Community Parimal Jivrajani Pre Annual Review Meeting Workshop of NE Region and XXIII Annual Review Meeting of
Oncology & RD Patel National Cancer Registry Programme, Aizawl, Mizoram, November 2007
Medical Records Jayesh Solanki
Parimal Jivrajani Short course on Health Data Management and Statistical Software, Department of
Biostatistics Christian Medical College, Vellore, Tamilnadu, March 2008
Himanshu Patel CME on Research Methodology & Application of Biostatistics in Health Sciences,
Jayesh Solanki Ahmedabad, January 2008
Vishruti Pandya
Aarti Vasani
LECTURES BY GUEST FACULTIES
APRIL 2007 - MARCH 2008
Name of the Guest Speaker Country Topic Date
Dr. Lakshmi Madabusi India RNA interference in 2007 July 10, 2007
Dr. Lakshmi Iyer USA Angiogenesis in cancer research July 24, 2007
Dr. Girish Shah USA Recent advances in prostate cancer November 11, 2007
THE GUJARAT CANCER & RESEARCH INSTITUTE
V Proof
100
VII. LIST OF INSTRUMENTS
No. Name of the Instruments Year of Cost in Rs.
Purchase
HISTOPATHOLOGY
1. Cryocut Microtome 1980 45,403
2. Automatic Tissue Processor 1985 2,37,247
3. Cryostat Bench Standing Microtome 1987 86,010
4. Baush & Lomb Galen III Microscope 1989 81,716
5. Nikon Japan Binocular Research Microscope 1994 3,46,317
6. Rotary Microtome BRIGHT 5040 1995 3,97,988
7. Nikon Japan Bionocular Research Microscope LABOPHOT - 1995 4,84,096
Y2 45
8. Cryostat Bench Model BM/FAS-001 'BRIGHT' 1995 4,30,954
9. Leitz Binocular Microscope Model LABORRUX-5 1995 6,40,026
10. Shandon Laboratory Equipment (Histocentre, pathcentre, 1997 23,18,185
Autosharp Microtome, knife, slide stainer, cytospine)
11. Leica Teaching Microscope DMLB 1997 2,94,429
12. Trinocular Phase Contrast Microscope with computer & 2002 15,40,950
Networking – 5 Nos “AXIOSTAR”
13. Yorco Automatic Tissue Processor YSI-103 – 2 Nos. 2003 2,82,891
14. Rotary Microtome Leica RM-2125 – 2 Nos. 2004 4,79,066
15. Tissue Floatation Bath - 2 Nos. 2004 11,000
16. Paraffin Dispenser - 2 Nos. 2004 21,000
17. Slide Warming Table - 1 No. 2004 5,500
18. Hot Air Oven - 1 No. 2004 11,000
19. Cryocut Frozen Section, Leica CM 1510S 2007 6,36,738
BIOCHEMISTRY
20. Fully Automatic Batch Analyzer Clinical System 700 1992 11,13,213
21. ABL 510 Computerized Blood Gas Analyzer 1994 9,40,241
22. Beckman Synchron CX-7 Delta Automatic Chemistry Analyzer 1997 61,99,909
CYTOLOGY
23. Cytocentrifuge 'Shandon' 1982 26,198
HAEMATOLOGY
24. Nikon Binocular Research Microscope - 2 sets. 1984 40,730
25. STIKS COULTER Automatic Cell Counter 1997 31,20,000
26. Sartorius Electronic Balance 1998 1,06,907
27. Blood Cell Counter with Three Parts Differential Count 2002 3,70,000
28. Blood Cell Counter Coulter ACT– 2 Nos 2004 8,00,000
29. Fully Blood Coagulation Analyzer ACL – 100 – 1 No. 2004 6,00,000
BLOOD BANK
30. Forma Scientific Platelet Incubator & Platelet Agitator 1997 3,29,775
31. CODA Automated EIA Analyser 1997 10,61,810
32. Baxter Optipress System 1997 5,90,000
33. Heavy duty refrigerated Centrifuge 1997 5,90,000
34. Blood Cell Separator Baxter 1997 14,50,000
35. Cell Saver Equipment 1998 1,06,600
36. Nikon Japan Trinocular lnverted Microscope Model TS-100 F 2000 3,58,054
37. Laminar Air Flow System AHL-16 2000 39,000
38. Blood Bank Refrigerated Centrifuge 2001 15,51,000
39. Blood Bag Refrigerated ‘Best’ 2001 64,790
101
No. Name of the Instruments Year of Cost in Rs.
Purchase
40. Hemo Pharm Blood Bag Tube Sealer BT-200 2001 1,26,000
41. Blood Irradiator-BARC 2001 15,00,000
42. Sterile Connecting Device for Sterile Tubing welder 2002 5,00,000
43. Biochemistry Analyzer BTR-830 – 2 Nos 2004 4,00,000
44. Remi Ultra Low Vertical -80 deg.C freezer 185 Ltr. 2004 2,90,503
45. Blood Collection Monitor - 2 Nos. 2007 2,34,963
46. Baxter's Donor Chair 4R4213 - 2 Nos. 2007 2,74,040
MICROBIOLOGY
47. Dias UV fast Automatic Micro plate Elisa Reader 1995 10,40,898
(Dynatech)
48. Horizontal High pressure Cylindrical Steam Sterilizer 1997 1,11,720
49. Bactec 9050 Blood Culture System 1999 4,77,000
50. Perkin Elmer PCR System (Thermal Cycler) - 9700 2000 6,25,455
51. Gel Electrophoresis GTH-15 2000 87,041
52. Millipore Water System 2000 50,000
53. Heraeus "Biofuge Primo R" Micro Centrifuge 2000 1,87,560
54. BOD Incubator -ATCIL 2000 61,000
55. Laminar Flow 2001 2,15,201
56. Ultra Low Deep Freezer 2001 3,30,000
57. Mediquip Horizontal High Pressure 1,35,000
Cylindrical Steam Sterilizer, Model HPS - II
IMAGING SERVICE
58. CT Scan Equipment CTW 4-40 1984 1,00,00,000
59. Panex EC Panaromic X-ray Equipment (Orthopenzograph) 1991 3,62,201
60. Diacam Gamma Camera 1994 1,03,67,987
61. Mammomat 3 stereo Mammography - 2 Nos. 1994 48,17,811
62. Automatic x-ray Film Processor 1995 1,54,976
63. Hitachi CT Scanner Model CT-W-2000 1995 1,73,28,181
64. Ultrasound Equipment & Portable Ultrasound 1997 13,30,000
65. Siemens I.I.T.V. Sireskop 5.45 X-ray Machine 1998 1,64,97,622
66. Sonography Machine – Logiq-200 Prodigital 2002 11,00,000
67. Hitachi Permanent MRI Magnet Aperto - 0.4 Tesla 2005 2,61,59,753
68. Anclilary for MRI 2005 10,12,040
69. CCTV with Camera and Moniter 2005 6,25,000
70. SS Stracher Trolly and SS wheel chair 2005 41,040
71. Anesthesia Machine 2005 2,20,000
72. Pulse oximeter 2005 26,000
73. BPL Defrillaor with Monitors 2005 1,00,000
74. CR System (Fuji Computed radiography system-FCR XG-1 2005 32,00,000
(Single Cassettle Reader)-2 Nos.
75. Shimadzu high frequency X ray system 2 Red-50 2005 8,25,000
76. C.T. Scanner with C.T. Simulation 2005 2,00,00,000
77. Radio Frequency Tissue Ablation System - 1 No. 2007 10,04,000
78. Mobile X-Ray unit Model : 6010 FR - 2 Nos. 2007 2,58,750
NUCLEAR MEDICINE
79. 1) Mobile Barrier – Saxsons – 4 Nos. 2003 16,64,103
2) S.S. Lead Lined Waste Container Saxsons – 4 Nos.
3) Shielded Syringe Carrier Saxsons – 4 Nos.
4) Multiple Syringe Holder for unshielded syringe
102
No. Name of the Instruments Year of Cost in Rs.
Purchase
5) Saxsons – 4 Nos. 2005 12,25,000
6) L Beta Shield – 1 No.
7) Scintimamo Graphy Prone Breast Cushion –1 No.
8) ION Chamber Survey Meter – 1 No.
9) Fume Free Radiation Fume Hood ‘GAMMA SONIC’
10) Narrow Drawmed chair W / Molded Seat - 1 No.
11) Decontamination Kit Complete. – 1 No.
12) Primdent-35 Area Radiation Monitor – 2 Nos.
13) Isotop CAL / RAD mark-V - Dose Calibrator – 1 No.
14) Molydenum break - 1 No.
15) Label Printer for Dose Calibrator – 1 No.
16) Tech Mark Reusable Shielded Marker – 1 No.
17) Allvue vial shield – 2 Nos.
18) Cylindrical vial shield – 2
19) Radiation Resistant Lead Gloves – 7 Pairs
20) Pocket Dosimeter - 1 No.
21) Calibrator Reference Set
22) Radioiodine Therapy Facility Equipment
80. Infinia - Dual Head Spect Gamma Camera - 1 No. 2007 2,00,00,000
81. CRC-15 Beta Dose Calibrator 2007 5,50,147
Model : 5130-3097 (S/N : 510211) - 1 No.
OPERATION THEATRE
82. Operating Microscope 1979 1,75,644
83. Electro Surgical Generator / Diathermy 'DAVOL' 1981 36,418
84. Trolley Mounted Nova-II 1982 60,000
85. Cold Lights for Operation Theatre 1983 1,79,751
86. Leg Operated Sink Sterilizer 1983 72,910
87. Electrosurgical Generator 'HONDA' 1983 36,419
88. French make Angenisur Operting Theatres Light AX 14 1984 1,25,753
plus AX 4 & Accessories
89. Halogen Millian OT Light 1984 64,359
90. Cyto-Urethroscope 1986 27,253
91. Karl Storz Cystoscope 1986 58,106
92. Balmont Operating Table 1987 1,60,782
91. Valley Lab Force-4 Electro Surgical Generator 1988 1,17,040
92. Hospilight Halogen Million Light 1990 2,73,914
93. Operating Table DR 7700 B ‘BELMONT’ – 2 sets 1990 9,02,010
94. Spiro Analyzer ST 300 C 1990 1,43,900
95. National Panasonic TV Camera System for D.K.K. 1991 4,07,800
Operating Light
96. Infasomate Secure Pump 1993 89,200
97. Operating Table DR 7700 B ‘BELMONT’ 1993 9,99,903
98. Halogen Million O.T. light HA 4FL – 6 sets 1994 7,41,407
99. Rectangular Steam Sterilizer Auto Sliding Door 1994 1,70,572
100. Rectangular Steam Sterilizer 600 x 600 x 1200 mm 1994 4,54,860
single Door, No. 289
101. Lawton Vascular & Endoscopic Instruments 1994 9,38,296
102. Table Sterilizer small High speed Autoclave, No. 116 1995 37,905
103. Lawton Vascular & Endoscopic Surgical Instrument 1996 6,63,520
104. Operation Theatre Light ‘PHILIPS’ – 2 sets 1996 3,80,000
105. Horizontal H.P. Sterilizer 2x2x4 mm, No. 289 1997 6,46,800
106. Instrumental washer and disinfector No. 111 1997 74,480
103
No. Name of the Instruments Year of Cost in Rs.
Purchase
107. Hydraulic O.T. Table 1997 1,82,000
108. Horizontal H.P. Sterilizer 2x2x4mm No.291 1997 6,46,800
109. Horizontal High pressure cum Low Pressure ETO Sterilizer 2000 95,000
No. 514
110. Vital Sign Cardiac Monitor – 6 Nos. 2002 14,00,000
111. Portable Pulmonary Function Test (SPIROMETER) 2002 1,15,000
112. Anaesthesia Ventilator with Battery Backup MX-10AL – 3 Nos. 2003 2,40,000
113. Operating Laryngoscope with accessories “Karl Strorz” 2003 4,31,000
114. CO2 Laser PDR-30 JZ 2003 12,48,560
115. Therapeutical Laproscopic Set for MIS Surgery –1 set (Indian 2003 5,64,020
make)
116. Therapeutical Laproscopic Set for MIS Surgery – 1set 2003 5,24,520
(Germany)
117. Microclean Ceiling Suspended Laminar Airflow connected with 2003 1,94,750
Operation Light – 1 set
118. Fogaster-ULV Fogging Machine – 2nos. 2003 44,063
119. Ultrasonic Harmonic Scalpel (Gen-04) 2004 10,45,000
120. Ceiling Halogen Light Single Dome with 4X4 Reflector 2004 1,49,890
Model: AG 4 (Twin)
121. Laproscopic Instruments of Karl Storz Germany – 1set 2004 13,27,827
122. Leica Surgical Operating Zoom Microscope Model 2001 24,15,563
MS-1 with CCTV Camera
123. Manman New Mini Simple Burr Hand Piece (electronic) 2005 43,031
1 No.
124. Manman Driving Unit-1No. 2005 21,835
125. Manman pen type drill with 4 mm check 2005 10,241
New Mini Salttal saw Handpiece (electronic) 1No.
126. Under water Electro Surgical Unit 2005 1,08,000
HM-400 H with all Standard Accessories serial No. 183
2 No.
127. Sterrad Nx Hydrogen Peroxide Low temperature Gas Plasma 2005 2,00,000
Strilization system
128. Bronchscope Tube universal 2005 61,600
6.5×43 cm-7010318 A
8.5×43cm-7010318 B-2 No.
129. Fogstar- ULV Machine Formaldehyde Free Fumigation 2005 20,736
130. ECG Machine (Cardiograph) - 2 Nos. 2005 40,800
131. Manman Bone Cutting Drilling & 2005 1,80,580.80
Reaming Sys.
132. Orthopaedic Instruments 2005 2,43,000
133. General Surgical Instruments (Main OT, DSU, Neuro ward, 2005
CSSD) 9,79,864
134. Baxter's Syringe Pump Model- SEP-10S- 1 No. 2007 29,120
135. Drager Ventilator Model-Oxylog 3000 - 2 Nos. 2007 11,48,470
136. Philips Sure Sign VM6 Monitor - 4 Nos. & 2007 14,00,000
Philips MP20J Monitor - 2 Nos.
137. Horizontal Rectangular Type Steam Sterilizer Pressure type - 2008 6,43,500
1
138. Under Water Electro Surgical Unit HM-400H - 1 No. 2007 54,000
139. Baxter's Syringe Pump Model- SP-12S PRO - 2 Nos. 2007 58,240
104
No. Name of the Instruments Year of Cost in Rs.
Purchase
140. Halogen Ceiling Light 1) Sunlite 2001 C-GL - 4 Nos. 2007 5,60,000
2) Sunlite 2001-1 C-GL - 2 Nos.
INTERVENTIONAL THERAPEUTIC CENTRE
141. Peritoneoscope,Cystoscope Cholangiography Sigmoidoscopy 1984 2,35,693
with Accessories
142. Karl Storz Endoscopes with Accessories 1986 8,39,227
143. Diagnost-5 Compact Image Intensifier Integrated X-ray 1988 10,11,111
System
144. Tracheal Intubation Fiber scope 'Olympus' 1992 2,23,168
145. Colonovideoscope CFIT 100 'Olympus'. 1994 8,94,321
146. Video Olympus Endoscopes TJF 200 GIF 2T 200 1996 37,41,297
BFIT 200
147. PENTEX Fiberoptic Gastroscope with standard accessories. 2003 3,19,500
Model FG-29V
148. PENTEX Fiberoptic Colonoscope with standard accessories & 2003 4,49,000
light source Model FC-38LV
149. Video Endoscopic System “PENTEX” 2003 18,50,500
1) Gastroscope with accessories EG-2930 K
2) Duodenoscope with accessories ED-3430TK
3) Colonoscope with accessories EC-3830 LK
150. Fiber Optic Bronchoscope BF-TE2 2004 4,07,000
SURGICAL ONCOLOGY
151. Urolose Fibre 1995 2,32,203
152. 1) Compact drainage pump 1996 7,30,297
2) Universal Secretion
153. Lawton Vascular & Endoscopic surgical Instruments. 1996 2,25,526
154. Micro Processor Controlled solid state electro surgical unit 1997 10,43,000
Bovie X-10 - 2 Sets
155. Surgical Diatherapy 1997 2,25,000
156. Biopty Biopsy Inst. with Needle BARD 2000 88,950
NEUROSURGERY
157. 1) Siemens Siremobil compact economic IITV 1997 59,31,400
System with C-Arm
2) Siemens Siremobil 1000-2 Mobile X-ray I.I. with
C-Arm D.S.A.
158. M 1205 A, Omicare 14 - 4 channel LCD Modular Monitoring 1997 7,78,724
System
159. HP Medical M.1166 A - 6 channel color Anesthesia, 1997 30,77,100
component monitoring System
160. Excel 2lose Ohmeda Anesthesia System - 2 sets 1997 19,46,966
161. Bear 1000 Micro Processor Ventilator - 2 sets 1997 23,85,846
162. System 6000 Argon Beam Coagulator - 2 sets 1997 14,83,741
163. Carl Zeiss Surgical Operating zoom microscope OPMI Pro- 1997 15,77,623
magic
164. Lawton Microsurgical Instruments & Endoscopic 1997 18,43,517
Surgical Instruments
165. Hilan High Speed Motor System 1997 10,16,800
166. Maquet ALPHASTAR 1132.01 Universal Mobile Operating 1997 23,62,718
Table - 2 sets
167. Valleylab CUSA System 200 1997 26,31,000
168. Philips O.T. Light for Neurosurgery - 2 sets 1997 4,18,000
169. Radionics Linear Accelerator Stereotactic Radiation System 1998 1,50,18,345
105
No. Name of the Instruments Year of Cost in Rs.
Purchase
170. Multi Purpose Head Frame Type II set 1998 6,89,216
171. Mizuho Sugita Neuro Surgical Instruments 1998 3,75,281
172. Horizontal H.P. Cylindrical Steam Sterilizer 20 x 48 1998 1,78,752
173. H.P. cum regular speed ETO Sterilizer Single Door 20x48 1998 2,01,096
174. Gloves Processing Unit 1998 1,91,520
1) Gloves Inspecting Machine
2) Gloves Washing Machine
3) Gloves Drying
175. Table Top Sterilizer 24W x 16L x 20D 1998 44,688
176. Table Top ETO Sterilizer 1998 78,800
177. Various Neuro Surgical Instruments 2000 6,33,920
178. Intra Cranial Pressure Monitoring System – 2 2001 5,86,992
179. High Speed Pneumatic Craniotome with Drill 2002 10,42,608
“MIDAS REX”
180. CRW Target Calculations software Stereocalc 2003 2,20,000
SC-SW-1CD – Radionics
181. Micro Surgical Instruments & Instruments for Spinal Fusion 2003 97,073
“SISCO” – 24 items – 69 Nos.
182. Manman Cranitome complete 1 No. 2005 1,11,937
183. Q cutler CRANITOME 2005 13,417
5 No. (set)
184. Fogstar- ULV Machine Formaldehyde Free Fumigation Denice 2005 20,736
1 No.
GYNAECOLOGICAL ONCOLOGY
185. Carl Zeiss Colposcope OPMI IFC 1989 3,33,600
186. Leisgang Standard Colposcope Model ID 1991 1,05,134
187. Colposcope OPMI 1-FC-2 Nos. 1994 16,03,854
MEDICAL ONCOLOGY
188. BEAR 1000 Ventilator 1993 15,36,405
189. BCI 9100 Series Multigas Monitor 1994 20,35,952
190. Anaesthesia Apparatus Excel '80' - 2 sets 1997 9,00,000
191. Volumetric Infusion pump - 12 sets 1998 7,48,800
192. Revco Ultra Low Temp Deep Freezer - 140°C 1999 10,31,056
193. Computer Controlled Rate Freezer Ice cute 181°C 1999 8,02,515
194. Liquid Nitrogen Ultra Deep Freezer 10K Cry storage 1999 5,35,260
System -180°C
195. 153013 HAMILTON AMADEUS Ventilator 1999 6,84,856
196. Blood Cell Separator C.S. 3000 Plus "BAXTER" 1999 20,85,300
197. Baxter SPS-1550-Hemodialysis machine 1999 7,22,228
198. S.S. scrub machine 1999 5,70,145
199. Volumetric Infusion Pump Infutec 520 S (4 Nos) 1999 2,06,000
200. Cardiac Resuscitation System 1999 3, 48,732
201. Concept Multipara Monitor with printer - 5 Nos 1999 8,55,625
202. Cardiac Resuscitation System 1999 3, 48,732
203. Concept Multipara Monitor with printer - 5 Nos 1999 8,55,625
204. BPL Defibrillator with cardiac Monitor Model DF-2509 - 2 Nos 2004 2,00,000
205. Pulse Oximeter Model - OXI-SAT 2060 - 2 Nos. 2007 71,370
206. Baxter's Syringe Pump Model- SEP-10S- 2 Nos. 2007 58,240
207. Pulse Oximeter Model - OXI-SAT 2060 - 1 No. 2007 35,685
106
No. Name of the Instruments Year of Cost in Rs.
Purchase
RADIOTHERAPY
208. Linear Accelerator SL 75-5 Sr.No. 327 'PHILIPS' 1980 67,41,653
209. Selectron Equipment 1983 12,50,000
210. Simulator Equipment 'PHILIPS' 1983 31,00,000
211. Linear Accelerator SL-75-5 Sr.No. 3021 'PHILIPS' 1989 75,24,243
212. 'Nucletron' Treatment Planning System 1993 14,06,150
213. Linear Accelerator 20 MEV Sr.No.5232 ‘PHILIPS’ 1993 2,53,19,708
214. Micro Selectron HDR Brachytherapy 1995 18,72,624
215. Varian Ximatron CX Radiotherapy Simulator 1997 1,54,46,200
216. Digital Plate Film Recorder 1997 3,74,293
217. Siemens or Doppler Ultrasound G-50 1998 20,00,000
218. 'Nucletron' Plato Treatment Planning System 2000 2 9,43,769
219. 15 MEV Precise Digital Linear Accelerator 2001 5,13,00,000
220. Plato 3D Radiotherapy Treatment Planning System & 2003 4,03,711
accessories for LA-4.
Networking TPS to Precise Digital Linear Accelerator
221. ION chamber Based Survey Meter (451P-RyR Inovision) 2004 1,30,890
222. ICRT Applicator Set for Selectron LDR 2004 3,04,395
223. CVC Applicator Set for Micro-HDR 2004 1,34,450
224. E-Class Hopkins II Telescope 70o with Fiber Optic Light Cable 2005 83,100
& Light Source
225. Q. A. Equipment Blue Phantom Dosimetry system with 2005 61,63,722
Accessories
226. Upgrade of Precise Digital Linear Accelerator with MLC 2005 2,08,84,000
Hardware and IMRT Software
227. Digital cold Light Source 24 V, 252W twin 2005 12,000
228. E-Class Itopkins II Telescope 70° 4mm (Sr.No.6218435) 2005 51,300
Cat No.7230 (WACS) -1No.
229. Fiber Optic Light Cable 3.5 (Lot:MF) Cat.No.495NL 2005 19,800
230. Fogstar- ULV Machine Formaldehyde Free Fumigation 2005 20,736
231. (1) MicroSelectron HDR V3 Remote Afterloading 2007 1,75,44,000
Brachytherapy unit
232. (2) Microselectron HDR GENIE Brachytherapy system
233. Gamma Zone Monitor Model - PAM - 452 - 2 Nos. 2007 49,634
234. Low Energy Linear Accelerator (6MV) 2008 2,76,03,570
MEDICAL PHYSICS
235. PTW Dosimeter Aspirator 1996 4,11,196
CELL BIOLOGY
236. Photo Microscope-III ‘Zeiss’ 1980 2,24,069
237. Research Microscope 'Zeiss’ 1980 1,80,000
238. Vacuum Pump & Nova-II 1982 31,038
239. Photomicrographic Exposer 1982 10,200
240. Nikon Binocular Research Microscope - 4 1984 1,02,638
241. Sartorious Electronic Balance 1984 8,321
242. Lyophiliser 1989 2,27,893
243. Laboratory Microscope Olympus BHT 112 1991 64,562
244. Binocular Res. Microscope Nikon - 3 No 1992 2,41,581
245. Confocal Microscopy MRC - 1000 Biorad 1995 38,62,651
246. CO2 Incubator 2000 2,64,325.00
247. Automatic Karyotyping System with Fluorescence Microscope 2000 37,74,000
107
No. Name of the Instruments Year of Cost in Rs.
Purchase
248. ISIS Software for up gradation of Automatic Karyotyping 2004 5,98,758
IKAROS-3
249. Multicolor Karytyping system with compatible CCD Camera 2004 26,36,888
computer and Laser Colour Printer
250. LG-366 DMQ Capacity 350 Liters 2004 52,500
LG-454 TM Capacity 430 Liters
MOLECULAR ENDOCRINOLOGY
251. Brinkman Polytron Homogenizer 1981 28,315
252. Micro Rapid System Electrophoresis 1986 6,709
253. Automatic Gamma Counter H.P. COBRA 1991 6,39,000
254. Ultra Centrifuge 'Beckman' L7-65. 1992 16,23,810
255. Fotodyne System with MP 4 Camera 1993 2,51,000
256. GNA 200 Gel Electrophoresis 1993 2,43,641
257. Ultra Low Temperature Deep Freezer -80°C ULT-1386 1993 3,92,000
258. Mini Protein-II Cell Biorad 1993 33,802
259. Table Top Refrigerated Centrifuge Beckman GS-6R 1994 3,81,578
260. Elgastat Prima water purification system 1994 3,88,285
261. SLAB Gel Dryer 'Biorad' 1994 57,255
262. VCX-400 Microprocessor based Vibra-Cell Ultrasonic 1994 1,27,465
Processor
263. Refrigerated Centrifuge Avanti – 30 1995 6,67,737
264. Gene Amp PCR System 9600 Perkin - Elmer Cetsus 1995 5,71,366
265. Hybridization Oven Amersham RPN 2510 1995 84,731
266. Rotary Microtome Leica 2035-2 1995 4,51,789
267. D Gene Complete System, mini protean cell, Gel Dryer. 1996 3,54,000
'BIORAD'
268. High Speed Micro Centrifuge 'Sigma 113’ 1996 47,358
269. Rotor for Beckmann Centrifuge 1996 6,00,448
270. Liquid Scintillation Counter Wallac 1409 1996 8,76,400
271. Amersham Contamination Monitor 1997 42,574
272. Centrifugal Evaporator RC 10.10 1997 2,61,379
273. Ultima series Ultra Low temp. Deep Freezer - 860C 1997 9,09,357
ULT 2186 9V 'REVCO'
274. Milli Q plus System 1997 2,15,129
275. Spectrophotometer 2001 5,50,644
276. Water Purification System ZIXS 5010Y ELIX-10 2004 1,75,972
277. Microcentrifuge (RC-4815D Eltek) 2004 62,700
278. Tissue Microdismembratorl 2001 3,03,522
279. Multigas 3 S-R Refrigerated Table Top Centrifuge 2001 4,63,961
280. Liquid Nitrogen Cryostorage System 2001 3,64,750
281. Thermolab System Multiscan Spectrum UV 2002 12,36,200
Spectrophotometer with computer
282. Power Pack for Electrophoresis 2002 1,30,000
283. Real Time PCR System ABI Prisam - 7000 2004 24,44,352
284. Master Cycler CP Gradient with Manual Lid inclusive of control 2004 3,02,762
Panel (5340002.000) equipment
285. AIRTECH’ make Laminar Air flow cabinets. 2004 61,750
Size 4’×2’×2’ (Horizontal) Model: ATH 1200
108
No. Name of the Instruments Year of Cost in Rs.
Purchase
BIOCHEMISTRY RESEARCH
286. Microzone Electrophoresis System. 1980 28,069
287. HPLC DFB System & Electrophoresis System 1993 15,63,000
288. Ultima series Ultra Low temp. Deep Freezer - 860C ULT 1997 9,09,357
2186 9V 'REVCO'
289. Bio-Rad Densitometer 1997 19,80,847
integrated System
290. Beckman DU-640 Spectrophotometer 1997 9,36,869
291. Fluorescence Spectrophotomer 2001 15,21,237
292. Systronics Double Beam UV-VIS Spectrophotometer 2003 3,03,441
Type 2201
293. Proteomic Work Station (Protean IEF System) 2004 16,04,805
IMMUNOHISTOCHEMISTRY
294. Hyper Cut Rotary Microtome 'Shandon' 1985 61,867
295. Rotary Microtome Leica 2035-2 1995 4,51,789
296. Facsort Flow Cytometer System 1995 41,26,490
297. LeitzAdvanceresearch Microscope Model DMRB with Micro 1995 7,10,844
Pathology
298. Electro Transfer System Blotting Apparatus 2005 26,180
PHYSIOTHERAPY
299. Intermittent Compresion Therapy Unit 2007 1,35,169
(Pression Compression 6 Chamber) - 1 No.
WARDS
300. Servoventilator 900 C – Siemens (ICU) 1989 4,46,500
301. Air Sterilizer 2002 2,55,368
4 Nos (Leukemia F. Ward)
2 Nos (Leukemia M. Ward)
2 Nos(Paediatric Leukemia)
2 Nos(BonemarrowspWard)
2 Nos (Special Ward)
302. Pulse oximeter with Alrams 2005 1,04,000
Model: TOP SAT-DX
1 No (PostOp Ward)
1 No. (ICU)
2 Nos (BMT unit / Medical Ward)
303. Fire extinguishers 2005 1,86,500
ABC MAP 90 (SP) FE 2 Kg- 34 Nos.
ABC MAP 90 (SP) FE 5 Kg-13 Nos.
CleanAgent HCFC 123 FE 2 Kg-6 Nos.
Clinical Meetings, Conferences, Workshops, Seminar & Video Conference
304. Multimedia Projector - 3 Nos 1,96,620
COC, Vasna
305. LCD Projector 2004 79,178
306. Olympus Binocular Microscope 2004 73,000
Total Cost 50,49,01,991=00
109
THE GUJARAT CANCER & RESEARCH INSTITUTE
VIII. ACCOUNTS
BALANCE SHEET
2007-2008
The Gujarat Cancer & Research Institute
Civil Hospital Campus, Asarwa, Ahmedabad-380 006
Tel : 079-22688000 • Fax : 079-22685490
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THE GUJARAT CANCER & RESEARCH INSTITUTE
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ACADEMIC ACTIVITIES INITIATED IN MEMORY OF DR. T.B. PATEL
DR. T. B. PATEL ORATION AWARD
In the memory of Dr. T. B. Patel, Oration Award is given every year to an individual who has
substantially contributed for more than ten years in the field of cancer. Dr. T. B. Patel Award was
instituted in 1991. The list of recipients of the Oration Award is as follows:
1991-1992: Dr. M. R. Das, Director, Centre for Cellular Molecular Biology, Hyderabad.
1992-1993: Dr. John Leuis, Leeds, U. K.
1993-1994: Dr. Ashok Khar, Centre for Cellular Molecular Biology, Hyderabad.
1994-1996: Dr. N. Anantha, Director & HOD, Dept. of Radiation Therapy, Kidwai Memorial
Institute, Bangalore
1997-1998: Dr. Bhanu Iyenger, HOD, Institute of Pathology (ICMR), New Delhi.
1998-1999: Dr. Mamen Chandy, Christian Medical College, Vellore, Tamil Nadu.
1999-2000: Dr. Sanat Bhagwati, Consultant Neuro Surgeon, Bombay Hospital, Mumbai.
2001-2002: Dr. G. K. Rath, Prof. & Head, Dept. of Radiation Oncology, AIIMS, New Delhi.
2002-2003: Dr. Vinod Kochupillai, Prof. & Head, Dept. of Medical Oncology, AIIMS, New Delhi.
2003-2004: Padmavibhushan Dr. Praful Desai, Ex-Director Tata Memorial Hospital, Mumbai.
2004-2005: Dr. Rajendra A. Badve, Professor and Head, Surgical Oncology, Tata Memorial
Hospital, Mumbai.
2005-2006: Dr. V. Shanta, RCC, Chennai.
2006-2007: Dr. M. B. Agarwal, Haematologist, Bombay Hospital, Institute of Medical Sciences,
Mumbai.
2007-2008: Dr. K. S. Gopinath, Director, HCG Bangalore Institute of Oncology, Bangalore.
Special Oration Award:
2000-2001: Dr. Sen Pathak, Prof. Cell Biology, University of Texas, M.D. Anderson Cancer
Center, USA.
DR. T. B. PATEL TRAVEL FELLOWSHIP 2007 - 2008
No. Name Department / Division
1 Mr. Gaurav Pancholi Biochemistry Research
2 Ms. Vandana Patel Biochemistry Research
3 Dr. Mithun Shah Medical Oncology
4 Dr. Kiran A.K. Medical Oncology
5 Dr. Nitin Joshi Pediatric Oncology
6 Dr. Bharat Parikh Medical Oncology
7 Ms. Birva Brahmbhatt Immunohistochemistry
8 Ms. Nilima Desai Immunohistochemistry
9 Dr. Ronak Bhansali Gynaecological Oncology
10 Ms. Kruti Rajvik Immunohistochemistry
11 Ms. Shalvi Mehta Immunohistochemistry
12 Dr. Pariseema Dave Gynaecological Oncology
13 Dr. Shilpa Patel Gynaecological Oncology
14 Dr. Dhaval Jetly Pathology
15 Dr. Parijath Goswami Microbiology
16 Dr. Biren Parikh Pathology
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DR. T. B. PATEL YOUNG SCIENTIST RESEARCH MEDALS
Gold, Silver and Bronze medals are awarded to young scientists for their outstanding published
research work. For the purpose of this felicitation, only the Research Fellows, Residents,
Research Assistants are considered. The medals are given as a mark of appreciation of the
enthusiastic research workers, at the same time it is hoped that it may also encourage the
budding brilliance to turn into a full-blown scientist some day in the future. These Medals were
instituted in 1991-92. For the first two years, only gold medals were given. From 1997, Gold,
Silver and Bronze Medals are being given.
Year Recipient Medal Department / Division
1991-1992 Dr. Prabhudas Patel Gold Biochemistry Research
Dr. Neelam Shah Gold Molecular Endocrinology
Dr. Amit Trivedi Gold Cell Biology
1992-1993 Dr. Hemangini Vora Gold Molecular Endocrinology
Dr. Nandita Ghosh Gold Molecular Endocrinology
Ms. Rina Jaju Gold Cell Biology
1993-1994 Dr. Neelkamal Karelia Gold Molecular Endocrinology
Mrs. Rashmi Patel Silver Cell Biology
Ms. Gira Raval Bronze Biochemistry Research
1994-1996 Ms. Tejal Suthar Gold Molecular Endocrinology
Ms. Sonal Bakshi Silver Cell Biology
Mr. Rakesh Rawal Bronze Biochemistry Research
1997-1998 Ms. Mintoo Patel Gold Biochemistry Research
Ms. Priya Chikhlikar Silver Molecular Endocrinology II
1998-1999 Ms. Trupti Trivedi Gold Molecular Endocrinology II
Ms. Nilima Desai Silver Immunohistochemistry
1999-2000 Dr. Sonal Bakshi Gold Cell Biology
Ms. Beena Patel Silver Biochemistry Research
2001-2002 Ms. Harshini Mehta Gold Immunohistochemistry
Ms. Rachana Sainger Silver Biochemistry Research
Ms. Pina Trivedi Bronze Cell Biology
2002-2003 Ms. Franky Jha Gold Biochemistry Research
Ms. Hiral Broker Silver Molecular Endocrinology II
2003-2004 Ms. Rupa Dalal Gold Molecular Endocrinology II
Ms. Kruti Shah Silver Immunohistochemistry
Mr. Jayendra Patel Bronze Biochemistry Research
2004-2005 Ms. Manisha Brahmbhatt Gold Cell Biology
Dr. Ahsish Gupta Gold Medical Oncology
Ms. Amisha Desai Silver Biochemistry Research
Dr. Sonali Garg Bronze Gynaecological Oncology
2005-2006 Ms. Shalvi Mehta Silver Immunohistochemistry
Ms. Tina Dave Silver Biochemistry Research
Dr. Biren Parikh Bronze Pathology
2006-2007 Ms. Vandana Patel Gold Biochemistry Research
Dr. Bhavna Parikh Gold Surgical oncology
Ms. Birva Brahmbhatt Silver Immunohistochemistry
Dr. Madhuri Bhade Silver Anaesthesiology
Ms. Pina Trivedi Bronze Cell Biology
2007-2008 Dr. Pooja Nandvani Patel Gold Radiotherapy
Ms. Hetvi K. Patel Silver Biochemistry Research
Dr. Anjana Chauhan Silver Gynaecological Oncology
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ACKNOWLEDGEMENTS
Our sincere thanks and gratitude to:
Shri Nawal Kishore Sharma, His Excellency, The Governor of Gujarat
Shri Narendra Modi, Hon’ble Chief Minister, Gujarat State
Shri Jaynarayan Vyas, Hon’ble Health Minister, Gujarat State
Shri Sudhir Mankad, IAS, Chief Secretary, Govt. of Gujarat
Sushri Rita Teotia, Additional Chief Secretary, Health & Family Welfare Dept., GOG
Dr. Amarjeet Singh, IAS, Commissioner of Health, Govt. of Gujarat
Shri V.L. Joshi, IAS, Chairman & Managing Director, GMDC
Shri A.K. Joti, IAS, Secretary, Finance Dept. (Exp), Govt. of Gujarat
Shri K. Ramamoorthy, IAS, Joint Secretary, Ministry of Health & Family Welfare, Govt. of India
Addl. Director General, Dept. of General of Health Services, Govt. of India
Shri S.D. Jha, Director (IF), Ministry of Health & Family Welfare, Govt. of India
Shri Kanaji Thakor, Mayor, Ahmedabad Municipal Corporation
Shri I.P. Gautam, IAS, Municipal Commissioner, Ahmedabad
Dr. M.M. Prabhakar, Superintendent, Civil Hospital, Ahmedabad
Dean, Govt. Dental College, Ahmedabad
Dean, B.J. Medical College, Ahmedabad
Director General, Indian Council for Medical Research, New Delhi
Dr. A. Nandakumar, Officer-Incharge, ICMR, NCRP, Bangalore
Director, NIOH, Ahmedabad
Dr. Parimal Trivedi, Vice Chancellor, Gujarat University, Ahmedabad
Department of Health & Family Welfare, Govt. of Gujarat
Ministry of Health & Family Welfare, Govt. of India
Director General of Department of Science & Technology, New Delhi
Director General of Department of Biotechnology, New Delhi
Additional Director of Medical Education & Research, Gandhinagar
Shri K.R. Kaushik, IPS, Commissioner of Police, Ahmedabad
Gujarat Cancer Society, Ahmedabad
Social Organisations providing helping hand to our day today activities
All staff members of Gujarat Cancer & Research Institute and Gujarat Cancer Society Parivar
Annual Report Preparation Committee
Heads of Departments/ Units/ Services/ Research Divisions
Dr. Shilin Shukla (Convenor)
Dr. Hemangini Vora, Mr. Mahendra Kumpavat, Mr. Bankim Desai,
Mr. Dharmesh Panchal,
Heads of Administrative Sections
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